Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	motor neuron migration	RELN CELSR1 CELSR2	1.52e-05	15	68	3	GO:0097475
GeneOntologyCellularComponent	somatodendritic compartment	DAB2IP MAF1 NELL2 RELN PDE2A CLSTN3 ABL2 CSF1R ABITRAM DNER SPG11 GRIN3A GRIN3B USH2A	3.99e-05	1228	69	14	GO:0036477
GeneOntologyCellularComponent	AIM2 inflammasome complex	CASP1 CARD16	6.42e-05	4	69	2	GO:0097169
GeneOntologyCellularComponent	IPAF inflammasome complex	CASP1 CARD16	6.42e-05	4	69	2	GO:0072557
GeneOntologyCellularComponent	protease inhibitor complex	CASP1 CARD16	2.97e-04	8	69	2	GO:0097179
GeneOntologyCellularComponent	NLRP3 inflammasome complex	CASP1 CARD16	2.97e-04	8	69	2	GO:0072559
GeneOntologyCellularComponent	NMDA selective glutamate receptor complex	GRIN3A GRIN3B	3.81e-04	9	69	2	GO:0017146
GeneOntologyCellularComponent	dendrite	DAB2IP MAF1 NELL2 RELN PDE2A CLSTN3 ABL2 ABITRAM DNER SPG11	4.87e-04	858	69	10	GO:0030425
GeneOntologyCellularComponent	dendritic tree	DAB2IP MAF1 NELL2 RELN PDE2A CLSTN3 ABL2 ABITRAM DNER SPG11	4.96e-04	860	69	10	GO:0097447
GeneOntologyCellularComponent	postsynaptic specialization membrane	CLSTN3 RAPSN SLITRK5 GRIN3A GRIN3B	5.34e-04	201	69	5	GO:0099634
GeneOntologyCellularComponent	peptidase inhibitor complex	CASP1 CARD16	5.79e-04	11	69	2	GO:1904090
GeneOntologyCellularComponent	canonical inflammasome complex	CASP1 CARD16	1.59e-03	18	69	2	GO:0061702
GeneOntologyCellularComponent	postsynaptic density membrane	CLSTN3 SLITRK5 GRIN3A GRIN3B	1.81e-03	157	69	4	GO:0098839
Domain	EGF_1	NELL2 RELN CELSR1 CELSR2 DNER TENM1 LTBP3 USH2A SSPOP	2.69e-07	255	66	9	PS00022
Domain	EGF_3	NELL2 RELN CELSR1 CELSR2 DNER TENM1 LTBP3 SSPOP	1.71e-06	235	66	8	PS50026
Domain	EGF_2	NELL2 RELN CELSR1 CELSR2 DNER TENM1 LTBP3 SSPOP	4.17e-06	265	66	8	PS01186
Domain	Laminin_G_2	NELL2 CELSR1 CELSR2 USH2A	1.18e-05	40	66	4	PF02210
Domain	LamG	NELL2 CELSR1 CELSR2 USH2A	1.74e-05	44	66	4	SM00282
Domain	EGF	NELL2 RELN CELSR1 CELSR2 DNER TENM1 LTBP3	1.89e-05	235	66	7	SM00181
Domain	-	NELL2 CLSTN3 CELSR1 CELSR2 USH2A	2.14e-05	95	66	5	2.60.120.200
Domain	EGF-like_dom	NELL2 RELN CELSR1 CELSR2 DNER TENM1 LTBP3	2.74e-05	249	66	7	IPR000742
Domain	ASX_HYDROXYL	NELL2 CELSR1 CELSR2 DNER LTBP3	2.74e-05	100	66	5	PS00010
Domain	zf-RING_2	RNF167 RAPSN RCHY1 RNF13	3.39e-05	52	66	4	PF13639
Domain	EGF-type_Asp/Asn_hydroxyl_site	NELL2 CELSR1 CELSR2 DNER LTBP3	3.63e-05	106	66	5	IPR000152
Domain	EGF-like_CS	NELL2 RELN CELSR1 CELSR2 DNER TENM1 LTBP3	3.70e-05	261	66	7	IPR013032
Domain	Laminin_G	NELL2 CELSR1 CELSR2 USH2A	5.23e-05	58	66	4	IPR001791
Domain	EGF_extracell	NELL2 RELN DNER TENM1	5.98e-05	60	66	4	IPR013111
Domain	EGF_2	NELL2 RELN DNER TENM1	5.98e-05	60	66	4	PF07974
Domain	EGF_CA	NELL2 CELSR1 CELSR2 DNER LTBP3	7.12e-05	122	66	5	SM00179
Domain	EGF-like_Ca-bd_dom	NELL2 CELSR1 CELSR2 DNER LTBP3	7.69e-05	124	66	5	IPR001881
Domain	hEGF	CELSR2 DNER LTBP3	1.30e-04	28	66	3	PF12661
Domain	EGF_LAM_2	CELSR1 CELSR2 USH2A	1.60e-04	30	66	3	PS50027
Domain	EGF_LAM_1	CELSR1 CELSR2 USH2A	1.60e-04	30	66	3	PS01248
Domain	Tyr_kinase_CSF1/PDGF_rcpt	CSF1R KIT	1.83e-04	6	66	2	IPR016243
Domain	Growth_fac_rcpt_	NELL2 CELSR1 CELSR2 DNER LTBP3	2.26e-04	156	66	5	IPR009030
Domain	Laminin_EGF	CELSR1 CELSR2 USH2A	2.54e-04	35	66	3	PF00053
Domain	EGF_Lam	CELSR1 CELSR2 USH2A	2.54e-04	35	66	3	SM00180
Domain	LAM_G_DOMAIN	CELSR1 CELSR2 USH2A	3.25e-04	38	66	3	PS50025
Domain	Laminin_EGF	CELSR1 CELSR2 USH2A	3.25e-04	38	66	3	IPR002049
Domain	Tyr_kinase_rcpt_3_CS	CSF1R KIT	3.40e-04	8	66	2	IPR001824
Domain	RECEPTOR_TYR_KIN_III	CSF1R KIT	3.40e-04	8	66	2	PS00240
Domain	ZF_RING_1	RNF167 RNF166 RAPSN RCHY1 RNF13 DCST1	5.64e-04	291	66	6	PS00518
Domain	ZF_RING_2	RNF167 RNF166 RAPSN RCHY1 RNF13 DCST1	6.38e-04	298	66	6	PS50089
Domain	GAIN_dom_N	CELSR1 CELSR2	6.63e-04	11	66	2	IPR032471
Domain	GAIN	CELSR1 CELSR2	6.63e-04	11	66	2	PF16489
Domain	RING	RNF167 RNF166 RAPSN RCHY1 RNF13 DCST1	7.21e-04	305	66	6	SM00184
Domain	Znf_RING	RNF167 RNF166 RAPSN RCHY1 RNF13 DCST1	1.02e-03	326	66	6	IPR001841
Domain	ConA-like_dom	NELL2 CLSTN3 CELSR1 CELSR2 USH2A	1.06e-03	219	66	5	IPR013320
Domain	zf-C3HC4	RNF167 RNF166 RAPSN RCHY1 RNF13	1.15e-03	223	66	5	PF00097
Domain	CARD	CASP1 CARD16	1.43e-03	16	66	2	SM00114
Domain	Iontro_rcpt	GRIN3A GRIN3B	1.81e-03	18	66	2	IPR001320
Domain	Lig_chan-Glu_bd	GRIN3A GRIN3B	1.81e-03	18	66	2	PF10613
Domain	Iono_rcpt_met	GRIN3A GRIN3B	1.81e-03	18	66	2	IPR001508
Domain	Glu/Gly-bd	GRIN3A GRIN3B	1.81e-03	18	66	2	IPR019594
Domain	Lig_chan-Glu_bd	GRIN3A GRIN3B	1.81e-03	18	66	2	SM00918
Domain	Lig_chan	GRIN3A GRIN3B	1.81e-03	18	66	2	PF00060
Domain	PBPe	GRIN3A GRIN3B	1.81e-03	18	66	2	SM00079
Domain	VWC_out	NELL2 SSPOP	2.02e-03	19	66	2	SM00215
Domain	PA	RNF167 RNF13	2.02e-03	19	66	2	PF02225
Domain	PA_domain	RNF167 RNF13	2.02e-03	19	66	2	IPR003137
Domain	Znf_C3HC4_RING-type	RNF167 RNF166 RCHY1 RNF13	3.21e-03	172	66	4	IPR018957
Domain	HormR	CELSR1 CELSR2	3.50e-03	25	66	2	SM00008
Pathway	WP_IMATINIB_AND_CHRONIC_MYELOID_LEUKEMIA	CSF1R KIT NOP2	4.06e-05	20	48	3	M39381
Pubmed	Abl family kinases regulate endothelial barrier function in vitro and in mice.	ABL2 CSF1R KIT	4.16e-07	8	69	3	24367707
Pubmed	Ethanol potentiates HIV-1 gp120-induced apoptosis in human neurons via both the death receptor and NMDA receptor pathways.	CASP1 GRIN3A GRIN3B	2.68e-06	14	69	3	15749123
Pubmed	Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus.	CELSR1 CELSR2 SSPOP	3.34e-06	15	69	3	20473291
Pubmed	Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family--oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.	CSF1R KIT	3.88e-06	2	69	2	2456920
Pubmed	Nucleotide sequence, genomic organization, and chromosomal localization of genes encoding the human NMDA receptor subunits NR3A and NR3B.	GRIN3A GRIN3B	3.88e-06	2	69	2	11735224
Pubmed	Differential effects of CSF-1R D802V and KIT D816V homologous mutations on receptor tertiary structure and allosteric communication.	CSF1R KIT	3.88e-06	2	69	2	24828813
Pubmed	Drosophila ATP6AP2/VhaPRR functions both as a novel planar cell polarity core protein and a regulator of endosomal trafficking.	CELSR1 CELSR2	3.88e-06	2	69	2	23292348
Pubmed	Activating mutation in the catalytic domain of c-kit elicits hematopoietic transformation by receptor self-association not at the ligand-induced dimerization site.	CSF1R KIT	3.88e-06	2	69	2	9949175
Pubmed	Tumour-associated mutations of PA-TM-RING ubiquitin ligases RNF167/RNF13 identify the PA domain as a determinant for endosomal localization.	RNF167 RNF13	3.88e-06	2	69	2	24387786
Pubmed	Distinct actions of testicular endocrine and lumicrine signaling on the proximal epididymal transcriptome.	NELL2 KIT	3.88e-06	2	69	2	38600586
Pubmed	Genetic variation in N-methyl-D-aspartate receptor subunit NR3A but not NR3B influences susceptibility to Alzheimer's disease.	GRIN3A GRIN3B	3.88e-06	2	69	2	20016182
Pubmed	Sequence analysis of two genomic regions containing the KIT and the FMS receptor tyrosine kinase genes.	CSF1R KIT	1.16e-05	3	69	2	9027509
Pubmed	The Steel/W transduction pathway: kit autophosphorylation and its association with a unique subset of cytoplasmic signaling proteins is induced by the Steel factor.	CSF1R KIT	1.16e-05	3	69	2	1710023
Pubmed	CSF-1-induced Src signaling can instruct monocytic lineage choice.	CSF1R KIT	1.16e-05	3	69	2	28159742
Pubmed	The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development.	CELSR1 CELSR2	1.16e-05	3	69	2	11677057
Pubmed	Geleophysic Dysplasia	LTBP3 ADAMTSL2	1.16e-05	3	69	2	20301776
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	GREB1L TLK2 MAF1 RNF167 CLSTN3 ARMCX6 MIEF1 LTBP3 DPP3 NOP2	1.39e-05	925	69	10	28986522
Pubmed	Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death.	PLA2G4A GRIN3A GRIN3B	1.88e-05	26	69	3	9745929
Pubmed	Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing.	CASP1 CARD16	2.32e-05	4	69	2	11432859
Pubmed	Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors.	CASP1 KIT	2.32e-05	4	69	2	22948816
Pubmed	NR2 to NR3B subunit switchover of NMDA receptors in early postnatal motoneurons.	GRIN3A GRIN3B	2.32e-05	4	69	2	15813953
Pubmed	Cooperating mutations of receptor tyrosine kinases and Ras genes in childhood core-binding factor acute myeloid leukemia and a comparative analysis on paired diagnosis and relapse samples.	CSF1R KIT	2.32e-05	4	69	2	17960171
Pubmed	Expression of CSF-1/c-fms and SF/c-kit mRNA during preimplantation mouse development.	CSF1R KIT	2.32e-05	4	69	2	1374350
Pubmed	Lack of KIT or FMS internal tandem duplications but co-expression with ligands in AML.	CSF1R KIT	2.32e-05	4	69	2	14654075
Pubmed	The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.	CELSR1 CELSR2	2.32e-05	4	69	2	37224017
Pubmed	Platelets trigger perivascular mast cell degranulation to cause inflammatory responses and tissue injury.	PLA2G4A KIT	2.32e-05	4	69	2	32206714
Pubmed	Developmental expression profiles of Celsr (Flamingo) genes in the mouse.	CELSR1 CELSR2	2.32e-05	4	69	2	11850187
Pubmed	A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.	CLSTN3 DNER TENM1 KIT	3.33e-05	91	69	4	28558017
Pubmed	Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins.	CASP1 CARD16	3.86e-05	5	69	2	11536016
Pubmed	Dab2ip regulates neuronal migration and neurite outgrowth in the developing neocortex.	DAB2IP RELN	3.86e-05	5	69	2	23056358
Pubmed	KIT Is Required for Fetal Liver Hematopoiesis.	CSF1R KIT	3.86e-05	5	69	2	34395414
Pubmed	A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility.	NELL2 KIT	3.86e-05	5	69	2	37095084
Pubmed	Expression pattern and neurotrophic role of the c-fms proto-oncogene M-CSF receptor in rodent Purkinje cells.	RELN CSF1R	3.86e-05	5	69	2	9852586
Pubmed	NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility.	NELL2 KIT	3.86e-05	5	69	2	32499443
Pubmed	Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity.	CELSR1 CELSR2	5.79e-05	6	69	2	36712970
Pubmed	CNS macrophages differentially rely on an intronic Csf1r enhancer for their development.	CSF1R KIT	5.79e-05	6	69	2	33323375
Pubmed	Interleukin-1α controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33.	CASP1 CRLF2	5.79e-05	6	69	2	22802353
Pubmed	INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation.	CASP1 CARD16	5.79e-05	6	69	2	15383541
Pubmed	Biochemical and genetic characterization of multiple splice variants of the Flt3 ligand.	CSF1R KIT	5.79e-05	6	69	2	8896402
Pubmed	The murine form of TXK, a novel TEC kinase expressed in thymus maps to chromosome 5.	RFC1 KIT	5.79e-05	6	69	2	7579892
Pubmed	HIV-1 Tat causes apoptotic death and calcium homeostasis alterations in rat neurons.	GRIN3A GRIN3B	8.09e-05	7	69	2	11606043
Pubmed	Early embryonic expression patterns of the mouse Flamingo and Prickle orthologues.	CELSR1 CELSR2	8.09e-05	7	69	2	17937400
Pubmed	The human immunodeficiency virus type-1 transcription factor Tat produces elevations in intracellular Ca2+ that require function of an N-methyl-D-aspartate receptor polyamine-sensitive site.	GRIN3A GRIN3B	8.09e-05	7	69	2	14644469
Pubmed	Human immunodeficiency virus type 1 Tat protein directly activates neuronal N-methyl-D-aspartate receptors at an allosteric zinc-sensitive site.	GRIN3A GRIN3B	8.09e-05	7	69	2	12775422
Pubmed	Role of the inflammasome in defense against venoms.	CASP1 KIT	8.09e-05	7	69	2	23297192
Pubmed	Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95.	GRIN3A GRIN3B	8.09e-05	7	69	2	7569905
Pubmed	HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors.	GRIN3A GRIN3B	8.09e-05	7	69	2	22940423
Pubmed	HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity.	GRIN3A GRIN3B	8.09e-05	7	69	2	11483648
Pubmed	Tat, a human immunodeficiency virus-1-derived protein, augments excitotoxic hippocampal injury in neonatal rats.	GRIN3A GRIN3B	8.09e-05	7	69	2	10197777
Pubmed	Neurotoxic effects of the human immunodeficiency virus type-1 transcription factor Tat require function of a polyamine sensitive-site on the N-methyl-D-aspartate receptor.	GRIN3A GRIN3B	8.09e-05	7	69	2	12414113
Pubmed	Direct cytotoxicity of HIV-1 envelope protein gp120 on human NT neurons.	GRIN3A GRIN3B	1.08e-04	8	69	2	8804048
Pubmed	HIV-1 Tat induces neuronal death via tumor necrosis factor-alpha and activation of non-N-methyl-D-aspartate receptors by a NFkappaB-independent mechanism.	GRIN3A GRIN3B	1.08e-04	8	69	2	9651389
Pubmed	Loss of Bladder Epithelium Induced by Cytolytic Mast Cell Granules.	CASP1 KIT	1.08e-04	8	69	2	27939674
Pubmed	The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid.	GRIN3A GRIN3B	1.08e-04	8	69	2	8845955
Pubmed	HIV-1 envelope proteins gp120 and gp160 potentiate NMDA-induced [Ca2+]i increase, alter [Ca2+]i homeostasis and induce neurotoxicity in human embryonic neurons.	GRIN3A GRIN3B	1.08e-04	8	69	2	8563977
Pubmed	HIV-1 gp120-induced neurotoxicity to midbrain dopamine cultures.	GRIN3A GRIN3B	1.08e-04	8	69	2	8821747
Pubmed	Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity.	GRIN3A GRIN3B	1.08e-04	8	69	2	7695237
Pubmed	Human brain N-methyl-D-aspartate receptors regulating noradrenaline release are positively modulated by HIV-1 coat protein gp120.	GRIN3A GRIN3B	1.08e-04	8	69	2	8724036
Pubmed	The human immunodeficiency virus-1 protein transactivator of transcription up-regulates N-methyl-D-aspartate receptor function by acting at metabotropic glutamate receptor 1 receptors coexisting on human and rat brain noradrenergic neurones.	GRIN3A GRIN3B	1.08e-04	8	69	2	16489129
Pubmed	Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine.	GRIN3A GRIN3B	1.08e-04	8	69	2	8822372
Pubmed	Glucocorticoid modulation of gp120-induced effects on calcium-dependent degenerative events in primary hippocampal and cortical cultures.	GRIN3A GRIN3B	1.08e-04	8	69	2	10448428
Pubmed	Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase.	GRIN3A GRIN3B	1.08e-04	8	69	2	8955056
Pubmed	Evidence of HIV type 1 glycoprotein 120 binding to recombinant N-methyl-D-aspartate receptor subunits expressed in a baculovirus system.	GRIN3A GRIN3B	1.08e-04	8	69	2	10555109
Pubmed	Cleavage of human cytosolic phospholipase A2 by caspase-1 (ICE) and caspase-8 (FLICE).	CASP1 PLA2G4A	1.08e-04	8	69	2	9875225
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	NELL2 CLSTN3 CELSR1 CELSR2 ABCE1 DNER SLITRK5 LTBP3 DDX55 MTCH2	1.24e-04	1201	69	10	35696571
Pubmed	Protective role of Cop in Rip2/caspase-1/caspase-4-mediated HeLa cell death.	CASP1 CARD16	1.38e-04	9	69	2	16920334
Pubmed	D1/NMDA receptors and concurrent methamphetamine+ HIV-1 Tat neurotoxicity.	GRIN3A GRIN3B	1.38e-04	9	69	2	22552781
Pubmed	Cutting edge: nitrogen bisphosphonate-induced inflammation is dependent upon mast cells and IL-1.	CASP1 KIT	1.38e-04	9	69	2	22387558
Pubmed	Physical mapping of the Tec and Gabrb1 loci reveals that the Wsh mutation on mouse chromosome 5 is associated with an inversion.	RFC1 KIT	1.38e-04	9	69	2	8589683
Pubmed	Human immunodeficiency virus type 1 clade B and C gp120 differentially induce neurotoxin arachidonic acid in human astrocytes: implications for neuroAIDS.	GRIN3A GRIN3B	1.38e-04	9	69	2	21491143
Pubmed	Mast cells are required for full expression of allergen/SEB-induced skin inflammation.	KIT CRLF2	1.38e-04	9	69	2	23752044
Pubmed	Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity.	CASP1 KIT	1.73e-04	10	69	2	19734227
Pubmed	N-methyl-D-aspartate receptors mediate the phosphorylation and desensitization of muscarinic receptors in cerebellar granule neurons.	GRIN3A GRIN3B	1.73e-04	10	69	2	19332541
Pubmed	CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis.	CASP1 CARD16	1.73e-04	10	69	2	11821383
Pubmed	Death of cultured human neuroblastoma cells induced by HIV-1 gp120 is prevented by NMDA receptor antagonists and inhibitors of nitric oxide and cyclooxygenase.	GRIN3A GRIN3B	2.11e-04	11	69	2	8581564
Pubmed	HIV-1 Tat-mediated apoptosis in human blood-retinal barrier-associated cells.	GRIN3A GRIN3B	2.11e-04	11	69	2	24739951
Pubmed	A dual role for planar cell polarity genes in ciliated cells.	CELSR1 CELSR2	2.11e-04	11	69	2	25024228
Pubmed	Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells.	KIT CRLF2	2.11e-04	11	69	2	23603794
Pubmed	Effects of SDF-1alpha and gp120IIIB on apoptotic pathways in SK-N-SH neuroblastoma cells.	GRIN3A GRIN3B	2.11e-04	11	69	2	16481105
Pubmed	Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network.	RNF167 RNF166 RAPSN RCHY1	2.25e-04	149	69	4	19549727
Pubmed	Differential expression of the seven-pass transmembrane cadherin genes Celsr1-3 and distribution of the Celsr2 protein during mouse development.	CELSR1 CELSR2	2.53e-04	12	69	2	11891983
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVFC1 ERVK-19	2.53e-04	12	69	2	14557543
Pubmed	Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice.	CELSR1 CELSR2	2.53e-04	12	69	2	20631168
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	TLK2 THRB MBTPS2 NR5A2 SPG11 NAA40 TAF6 DDX55 OGA NOP2	2.77e-04	1327	69	10	32694731
Pubmed	A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure.	CELSR1 CELSR2	2.98e-04	13	69	2	26989192
Pubmed	Mesenchymal Vangl1 and Vangl2 facilitate airway elongation and widening independently of the planar cell polarity complex.	CELSR1 CELSR2	3.48e-04	14	69	2	39225402
Pubmed	Fli-1 is required for murine vascular and megakaryocytic development and is hemizygously deleted in patients with thrombocytopenia.	CSF1R KIT	3.48e-04	14	69	2	10981960
Pubmed	Erythro-myeloid progenitors contribute endothelial cells to blood vessels.	CSF1R KIT	3.48e-04	14	69	2	30258231
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	NOP9 EXOSC8 DPP3 FANCM OGA USH2A NOP2	3.66e-04	670	69	7	22990118
Pubmed	Molecular cloning of murine STAP-1, the stem-cell-specific adaptor protein containing PH and SH2 domains.	CSF1R KIT	4.01e-04	15	69	2	10679268
Pubmed	Directional neuronal migration is impaired in mice lacking adenomatous polyposis coli 2.	RELN APC2	4.01e-04	15	69	2	22573669
Pubmed	Neurotoxicity of human immunodeficiency virus-1: viral proteins and axonal transport.	GRIN3A GRIN3B	4.01e-04	15	69	2	21948112
Pubmed	A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.	CELSR1 KIT	4.57e-04	16	69	2	10932191
Pubmed	A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells.	CASP1 CARD16	4.57e-04	16	69	2	37225719
Pubmed	Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation.	CSF1R KIT	4.57e-04	16	69	2	10022833
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	DAB2IP NUP133 PLA2G4A RFC1 TAF6 NOP2	4.93e-04	503	69	6	16964243
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ABCE1 NUP133 NAA40 RFC1 TAF6 OGA NOP2 MTCH2	5.16e-04	934	69	8	33916271
Pubmed	Chemokine co-receptor CCR5/CXCR4-dependent modulation of Kv2.1 channel confers acute neuroprotection to HIV-1 glycoprotein gp120 exposure.	GRIN3A GRIN3B	5.18e-04	17	69	2	24086760
Pubmed	Inhaled Fine Particles Induce Alveolar Macrophage Death and Interleukin-1α Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation.	CASP1 CRLF2	5.18e-04	17	69	2	28002730
Pubmed	Genome-wide meta-analysis of systolic blood pressure in children with sickle cell disease.	THRB TENM1	5.81e-04	18	69	2	24058526
Cytoband	11p11.2	OR4C3 RAPSN MTCH2	2.62e-04	83	68	3	11p11.2
Cytoband	Ensembl 112 genes in cytogenetic band chr11p11	OR4C3 RAPSN MTCH2	1.55e-03	153	68	3	chr11p11
Cytoband	Xq25	TENM1 DCAF12L2	1.71e-03	41	68	2	Xq25
Cytoband	Ensembl 112 genes in cytogenetic band chrXq25	TENM1 DCAF12L2	2.33e-03	48	68	2	chrXq25
Cytoband	11q13.1	NAA40 LTBP3	3.98e-03	63	68	2	11q13.1
Cytoband	1q41	USH2A RPS6KC1	4.36e-03	66	68	2	1q41
Cytoband	Ensembl 112 genes in cytogenetic band chr11q13	PDE2A NAA40 LTBP3 DPP3	4.67e-03	454	68	4	chr11q13
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR2	1.66e-05	3	43	2	913
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR2	1.66e-05	3	43	2	1189
GeneFamily	Glutamate ionotropic receptor NMDA type subunits	GRIN3A GRIN3B	1.15e-04	7	43	2	1201
GeneFamily	Ring finger proteins	RNF167 RNF166 RAPSN RCHY1 RNF13	4.71e-04	275	43	5	58
GeneFamily	WD repeat domain containing\|Caspase recruitment domain containing\|Apoptosome	CASP1 CARD16	2.30e-03	30	43	2	959
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	CSF1R KIT	4.07e-03	40	43	2	321
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	APC2 ARMCX6	4.69e-03	43	43	2	409
GeneFamily	Nuclear hormone receptors	THRB NR5A2	6.05e-03	49	43	2	71
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_1000	GREB1L TLK2 RNF167 ABL2 MBTPS2 PEG3 NR5A2 DNER MSH4 RFC1 KIT	2.31e-05	770	66	11	gudmap_developingGonad_P2_ovary_1000
ToppCell	wk_08-11-Epithelial-PNS-FGFBP2+_Neural_progenitor\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	NELL2 PDE2A RAPSN APC2 TENM1	7.06e-06	177	67	5	15a5c96ea840376e54933ebe7a8334a11d9ce411
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER TENM1 GRIN3A KIT	7.66e-06	180	67	5	b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_GGT8P\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT SSPOP	7.87e-06	181	67	5	9842537f9a607d8557c43790008d175edab1f32c
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN OTOGL TENM1 USH2A SSPOP	8.52e-06	184	67	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN OTOGL TENM1 USH2A SSPOP	8.52e-06	184	67	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN OTOGL TENM1 USH2A SSPOP	8.52e-06	184	67	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GREB1L RELN DNER GRIN3A KIT	8.98e-06	186	67	5	310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GREB1L RELN DNER GRIN3A KIT	9.45e-06	188	67	5	0501a8aa850bd2e347020abd1cac4d8075738189
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GREB1L RELN DNER GRIN3A KIT	9.45e-06	188	67	5	433a25fe52914e07e7ba695881f9bcca2d9467ff
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GREB1L RELN DNER GRIN3A KIT	9.70e-06	189	67	5	f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GREB1L RELN DNER GRIN3A KIT	1.02e-05	191	67	5	7b386512284dfaa0e95358b28ee82632ee965e64
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GREB1L RELN DNER GRIN3A KIT	1.02e-05	191	67	5	fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER TENM1 GRIN3A KIT	1.05e-05	192	67	5	bf1943715085c4124b1675888b0615c9500ec888
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER TENM1 GRIN3A KIT	1.10e-05	194	67	5	02a9cc821c2b14aa7d0e55661a5fab66364474e1
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER TENM1 GRIN3A KIT	1.16e-05	196	67	5	7af6c5147ac859353504d19727dbe24f63a29dd4
ToppCell	367C-Myeloid-Dendritic-cDC2\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	ABL2 CSF1R CASP1 RNF13 CARD16	1.24e-05	199	67	5	4faf4ed555dac1e1d40f9a1e586a22656974436f
ToppCell	Neuronal-Inhibitory\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN DNER TENM1 GRIN3A KIT	1.27e-05	200	67	5	9ff8647e2de0b538e15929dca88ebb20ff7ab043
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GREB1L RELN DNER GRIN3A KIT	1.27e-05	200	67	5	862db57d043bdf3cb059fbfc8b29bc1eafdf64ec
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR--L1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GREB1L RELN DNER GRIN3A KIT	1.27e-05	200	67	5	a91345f268f13170c27309333603eb82400c9947
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GREB1L RELN DNER GRIN3A KIT	1.27e-05	200	67	5	d416a7be1a4e6232fb58a9687774da24821f1fdd
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Car10\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RELN DNER CASP1 GRIN3A	4.04e-05	127	67	4	f808c727c0817ed10e76eaffa9493a516e9a6b50
ToppCell	facs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR2 OTOGL NUF2 GRIN3B	6.08e-05	141	67	4	4aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCell	facs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR2 OTOGL NUF2 GRIN3B	6.08e-05	141	67	4	e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCell	facs-Heart-Unknown-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR2 OTOGL NUF2 GRIN3B	6.25e-05	142	67	4	759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RELN DNER GRIN3A KIT	7.33e-05	148	67	4	5e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RELN DNER GRIN3A KIT	8.13e-05	152	67	4	8ff5a178a8f3550d89a003c0858820aab3773386
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ARMCX6 TAF6 FANCM ADAMTSL2	8.99e-05	156	67	4	14e2f693a75f1075f40cc7b16ee430262a5de016
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_GGT8P\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	9.68e-05	159	67	4	72678dfedc152f524fac14ddb31d4fed1528d52a
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	GREB1L NELL2 RELN USH2A	1.07e-04	163	67	4	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	343B-Myeloid-Dendritic-cDC_proliferating_2\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	CELSR1 THRB MBTPS2 DDX55	1.09e-04	164	67	4	d7053de88ef8e42cac6726a40e72f212659ee034
ToppCell	facs-Lung-EPCAM-24m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN PDE2A CELSR1 NR5A2	1.17e-04	167	67	4	961e722442d786ab15d1e490941d2be265a9057a
ToppCell	facs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN PDE2A CELSR1 NR5A2	1.17e-04	167	67	4	3760efc35d4e7e9c2da1a20f9795ddea397e2206
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l48\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PDE2A ABCE1 MIEF1 RPS6KC1	1.25e-04	170	67	4	070d8683d1a5cc7d594ff0453c961a9bf982c2d0
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	1.34e-04	173	67	4	af85fb9f6e26a044ca4d23e5872039b1a7b73b1b
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-skeletal_muscle_satellite_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAPSN OTOGL PEG3 USH2A	1.37e-04	174	67	4	f230d23618a6487f2664efb2c677e0a4559e2bf4
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Lymphoid_DC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN MSH4 GRIN3B CRLF2	1.37e-04	174	67	4	16204ff504b7b382b4d90ca35003ad5336020e07
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLSTN3 PEG3 MIEF1 GRIN3A	1.40e-04	175	67	4	a5db428b078938627e61b7e944c1e0c1d61ac2da
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLSTN3 PEG3 MIEF1 GRIN3A	1.40e-04	175	67	4	8b498eea1ec1c1f27b171025c3d08adf3687bafc
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-Myeloid-Mast_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MSH4 KIT DCAF12L2 CRLF2	1.46e-04	177	67	4	0176ffa5e66fa684d0a8264af0db8f77fc391afd
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	1.53e-04	179	67	4	c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCell	tumor_Lymph_Node_/_Brain-Endothelial_cells\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	RELN PDE2A NR5A2 ADAMTSL2	1.63e-04	182	67	4	d7cce5dd7046f06bf40f00c9dbfa610722b03333
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DNER GRIN3A KIT SSPOP	1.70e-04	184	67	4	ae0a77e3e520a246b17776bb19503519636b02ee
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER TENM1 GRIN3A	1.70e-04	184	67	4	7f6c8912677764d438ab0555faca344d74c2f483
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2IP PDE2A DCST1 KIT	1.73e-04	185	67	4	742350093d90f96735dc73e3360cdd749bae63fd
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	1.73e-04	185	67	4	bdfa8c284bbc5e85c806327fbb7778cf16242a38
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RELN DNER GRIN3A KIT	1.73e-04	185	67	4	739260f8abebaf10a5cc49d91726278579e26170
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 CELSR2 LTBP3 CRLF2	1.77e-04	186	67	4	bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GREB1L DNER GRIN3A KIT	1.77e-04	186	67	4	77592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER TENM1 GRIN3A	1.81e-04	187	67	4	85f1678338a47d91e296f0620d4887f057eb7e70
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RNF167 CLSTN3 SSPOP RPS6KC1	1.81e-04	187	67	4	8c69fd469df2915c56ede534cee3ef23d5f64ebf
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GREB1L RELN DNER GRIN3A	1.81e-04	187	67	4	d2ffb2f34f07b0dd5d3cb3ee0275f46ebecf4146
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 CELSR2 LTBP3 CRLF2	1.88e-04	189	67	4	965e0e388251e7318f8b463816dc96ccb4658677
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	1.88e-04	189	67	4	979b7fa947538aa7ca4a219263da2575869a2caa
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	1.92e-04	190	67	4	3b8d1e66ae68c1eee64095e75195d76d97e24026
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	1.92e-04	190	67	4	56cc761e50fddfb5366391518b4d8e16589b6b42
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	1.92e-04	190	67	4	25d4b591f75c26e404a34c42f1742d580af6598d
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN PDE2A CELSR1 NR5A2	1.92e-04	190	67	4	a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	1.92e-04	190	67	4	be2b184a3559da41ba387ae0fdbeb9ae532868a5
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN PDE2A CELSR1 NR5A2	1.92e-04	190	67	4	0bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	1.92e-04	190	67	4	dc655e4782aab274f0c9b6e36a5ce315e3a1a4b9
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN PDE2A CELSR1 NR5A2	1.92e-04	190	67	4	26e2237f65cb43723c5da853831b40df2982d6e4
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CLSTN3 CELSR1 GPR68 KIT	1.96e-04	191	67	4	f1935e8f8467a2bc30588b7f2cc3b94e9c83b268
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CLSTN3 CELSR1 GPR68 KIT	1.96e-04	191	67	4	1161e465c50c2071764279e01cf08b1048cce0e3
ToppCell	facs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN PDE2A CELSR1 NR5A2	1.96e-04	191	67	4	48823a97c38263f2c6e58348214f5b62773a6368
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CLSTN3 CELSR1 GPR68 KIT	1.96e-04	191	67	4	7a4fe96989f72159385270c712342ba3e1ca6fc3
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ16 DNER SLITRK5 GRIN3A	1.96e-04	191	67	4	ece87127f85939e61b1048d968ed96f0e87c3a79
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNJ16 DNER SLITRK5 GRIN3A	1.96e-04	191	67	4	478e8341ee03b05501e2233e02cef5f97492c95d
ToppCell	PBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CLSTN3 CELSR1 GPR68 KIT	1.96e-04	191	67	4	c023ca893ceae19b54967096f6e2588dc39fa268
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN PDE2A CELSR1 NR5A2	1.96e-04	191	67	4	0eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	2.00e-04	192	67	4	f6ec683b2133b3095a1fcc06ca8605cf38f774b5
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	2.00e-04	192	67	4	63d1b3efe93e5ff939278ebe40bacb38218ea09b
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	2.00e-04	192	67	4	342842378c20267c5044bdd622515e8b9f895623
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	2.00e-04	192	67	4	bd3fa6c8fcb618db64d11f25cabaf08608957c35
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	2.00e-04	192	67	4	690b3d17c481159bc96b8bc7f6a66b51343ee858
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	2.00e-04	192	67	4	67d6230e32d446dcb12047fae2c3f1faa80dd720
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER TENM1 GRIN3A	2.04e-04	193	67	4	d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	2.04e-04	193	67	4	9f9eb241b0b82a6f12de6921c3acf6fed7cf65bb
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	2.04e-04	193	67	4	294cb5b580bb83fe0eb04f112d5507aac35d4d44
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	2.04e-04	193	67	4	3d3c45d5ff6f3396a1990615aae9fe176e799994
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER TENM1 GRIN3A	2.04e-04	193	67	4	e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCell	severe-B_cell\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CELSR1 THRB FANCM DCST1	2.08e-04	194	67	4	2fee6083fb56b16d1f04fd0b92ec622fd26ba3fa
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	2.08e-04	194	67	4	52aebb0b563e2c2058e7f0554ae870e47692b163
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	2.08e-04	194	67	4	6ac759828c41ffa974ee82842162caa959351dd1
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	2.08e-04	194	67	4	5d0b0d8e96f0e0297a4dba70a05d87081a4eb323
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	2.08e-04	194	67	4	bd06e2b8d8c06cddf2e4f58849b86e09013acae1
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	2.08e-04	194	67	4	4f758718a1233c25c25d99fc1b7b06f906b8b0a2
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Cajal_Retzius-36\|World / Primary Cells by Cluster	RELN DNER TENM1 GRIN3A	2.12e-04	195	67	4	bc76a0586cc78f013cb96a2444e63e3c5daa3bc7
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Cajal_Retzius\|World / Primary Cells by Cluster	RELN DNER TENM1 GRIN3A	2.12e-04	195	67	4	424d8e2bc7f7e68f74219de06dbbb671c8b4c24c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DNER GRIN3A KIT	2.12e-04	195	67	4	98ca9f3aa36211dde1e6f7f3817b9418c95e583e
ToppCell	severe-B_cell\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CELSR1 THRB FANCM DCST1	2.12e-04	195	67	4	0fc3c605609c9e6bdea15d73c45def2188ae5fb1
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-midbrain/hindbrain_cells\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	GREB1L DNER TENM1 GRIN3A	2.16e-04	196	67	4	0767581b69bc7e6334d580ca02ed1e831b7b55da
ToppCell	facs-Brain_Myeloid-Cortex_-18m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A RAPSN CSF1R RNF13	2.20e-04	197	67	4	e73ca8c8f42cbcc56eaa5fe3d69abd1ce7b7bbca
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ABL2 CSF1R SSPOP ADAMTSL2	2.20e-04	197	67	4	b597c292fc1cb381a4325fed15a32966c38def28
ToppCell	facs-Brain_Myeloid-Cortex_\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A RAPSN CSF1R RNF13	2.20e-04	197	67	4	81379fe6bd14a1ba26f4a159497262adcb600b18
ToppCell	facs-Brain_Myeloid-Cortex_-18m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A RAPSN CSF1R RNF13	2.20e-04	197	67	4	271c75f491d03bd248c7ec037ef02e39456f3ac0
ToppCell	systemic_lupus_erythematosus-flare-Myeloid-non-classical_monocyte-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CSF1R CASP1 RNF13 CARD16	2.20e-04	197	67	4	1463522df1b6358cbe3b5022a3e153878e9c9e43
ToppCell	facs-Brain_Myeloid-Cortex_-18m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A RAPSN CSF1R RNF13	2.20e-04	197	67	4	9db329c6fea532dd1afb624f4c29c92407f45568
ToppCell	facs-Brain_Myeloid-Cortex_-18m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE2A RAPSN CSF1R RNF13	2.20e-04	197	67	4	173c0c8de4e69882a9f91189deeb4a651fefe551
ToppCell	systemic_lupus_erythematosus-treated-Myeloid\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CSF1R CASP1 RNF13 CARD16	2.25e-04	198	67	4	f37578f156e8aed2ce30cfa837ae04dd18de05d0
ToppCell	wk_15-18-Endothelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	RELN PDE2A NR5A2 KIT	2.25e-04	198	67	4	dcf453e22dba90c0ae349fa6c3d4c20758bb95af
Drug	CpMn	DNER CASP1 CARD16	2.02e-06	9	67	3	CID000146199
Drug	1rww	CASP1 CARD16	8.53e-06	2	67	2	CID005289080
Drug	Diphenyl Ether Sulfonamide 10	CASP1 CARD16	8.53e-06	2	67	2	CID009887536
Drug	Biphenyl Sulfonamide 1	CASP1 CARD16	8.53e-06	2	67	2	CID010449481
Drug	1rwx	CASP1 CARD16	8.53e-06	2	67	2	CID005289610
Drug	Diphenyl Ether Sulfonamide 2	CASP1 CARD16	8.53e-06	2	67	2	CID015888281
Drug	Diphenyl Ether Sulfonamide 9	CASP1 CARD16	8.53e-06	2	67	2	CID015888283
Drug	Diphenyl Ether Sulfonamide 5	CASP1 CARD16	8.53e-06	2	67	2	CID015888282
Drug	arylsulfonamide analogue 16	CASP1 CARD16	8.53e-06	2	67	2	CID015888284
Drug	Diphenyl Ether Sulfonamide 7	CASP1 CARD16	8.53e-06	2	67	2	CID015888286
Drug	arylsulfonamide analogue 11	CASP1 CARD16	8.53e-06	2	67	2	CID015888279
Drug	Diphenyl Ether Sulfonamide 12	CASP1 CARD16	8.53e-06	2	67	2	CID010070710
Drug	AC1NR9V6	CASP1 CARD16	8.53e-06	2	67	2	CID005287535
Drug	AAF-cmk	CASP1 CARD16	8.53e-06	2	67	2	CID006610326
Drug	Cyclo(lys-pro)	CASP1 CARD16	8.53e-06	2	67	2	CID000194922
Drug	AC1NRAF8	CASP1 CARD16	8.53e-06	2	67	2	CID005287849
Drug	zinc oxide	MBTPS2 DNER CASP1 CARD16	1.21e-05	48	67	4	CID000014806
Drug	AC1L1B45	DNER CASP1 CARD16	1.93e-05	18	67	3	CID000001275
Drug	Tocainide hydrochloride; Down 200; 17.4uM; PC3; HT_HG-U133A	GREB1L MBTPS2 RCHY1 CASP1 OGA KLHL22	2.43e-05	196	67	6	4256_DN
Drug	Dabcyl-ice-edans	CASP1 CARD16	2.55e-05	3	67	2	CID005748518
Drug	AC1NBJ9O	CASP1 CARD16	2.55e-05	3	67	2	CID004468934
Drug	Beta-sistosterol [83-46-5]; Up 200; 9.6uM; PC3; HT_HG-U133A	PDE2A CSF1R ZNF155 RCHY1 CASP1 KLHL22	2.72e-05	200	67	6	4073_UP
Drug	AC1ODTZD	CASP1 CARD16	5.10e-05	4	67	2	CID007020821
Drug	AC1NUKW9	CASP1 CARD16	5.10e-05	4	67	2	CID005481610
Drug	cinchomeronate	CASP1 CARD16	5.10e-05	4	67	2	CID000010273
Drug	N1-33	NR5A2 DNER	8.48e-05	5	67	2	CID000062449
Drug	hqc	CASP1 CARD16	8.48e-05	5	67	2	CID005288581
Drug	Oxeclosporin	CASP1 CARD16	8.48e-05	5	67	2	CID006436153
Drug	Ac-YVAD-pNA	CASP1 CARD16	8.48e-05	5	67	2	CID000004338
Drug	AC1N3S5K	CASP1 CARD16	8.48e-05	5	67	2	CID004117381
Drug	LY293558	CASP1 CARD16 GRIN3B	9.34e-05	30	67	3	CID000127894
Drug	AC1L32TU	CASP1 CARD16 GRIN3B	9.34e-05	30	67	3	CID000107831
Drug	DTSSP	ABCE1 CASP1 CARD16	1.76e-04	37	67	3	CID000123933
Drug	rupintrivir	CASP1 CARD16	1.77e-04	7	67	2	CID006440352
Drug	Tenocyclidine	GRIN3A GRIN3B	1.77e-04	7	67	2	DB01520
Drug	Isatin analog 1	CASP1 CARD16	1.77e-04	7	67	2	CID000515950
Drug	Orphenadrine	GRIN3A GRIN3B	1.77e-04	7	67	2	DB01173
Drug	F1-G	CASP1 CARD16	1.77e-04	7	67	2	CID006852193
Drug	Inhibitor 47c	CASP1 CARD16	1.77e-04	7	67	2	CID005327301
Drug	Inhibitor 66b	CASP1 CARD16	1.77e-04	7	67	2	CID005327309
Drug	catalpol	CASP1 CARD16	1.77e-04	7	67	2	CID000091520
Drug	Disulfiram [97-77-8]; Up 200; 13.4uM; MCF7; HT_HG-U133A	GREB1L THRB RCHY1 CASP1 OGA	2.16e-04	185	67	5	2215_UP
Drug	AC1L1DN5	DNER CASP1 EXOSC8 CARD16	2.34e-04	102	67	4	CID000002423
Drug	AC1N0FHX	CASP1 CARD16	2.36e-04	8	67	2	CID003916227
Drug	bestatin methyl ester	CASP1 CARD16	2.36e-04	8	67	2	CID009927170
Drug	Ac-wehd-cho	CASP1 CARD16	2.36e-04	8	67	2	CID005311140
Drug	hydrochalcone	CASP1 CARD16	2.36e-04	8	67	2	CID000064802
Drug	Sunitinib	CSF1R KIT	2.36e-04	8	67	2	DB01268
Drug	Isatin Sulfonamide 26	CASP1 CARD16	2.36e-04	8	67	2	CID009800285
Drug	M-IBDET	CASP1 CARD16	2.36e-04	8	67	2	CID005464042
Drug	4-cyano-N-(2-(1-cyclohexen-1-yl)-4-(1-((dimethylamino)acetyl)-4-piperidinyl)phenyl)-1H-imidazole-2-carboxamide	CSF1R KIT	2.36e-04	8	67	2	ctd:C549569
Drug	denitro-nipradilol	CASP1 CARD16	2.36e-04	8	67	2	CID000135168
Drug	Isatin analog 2	CASP1 CARD16	2.36e-04	8	67	2	CID010826725
Drug	Imatinib	CSF1R KIT	2.36e-04	8	67	2	DB00619
Drug	Ethynodiol diacetate [297-76-7]; Up 200; 10.4uM; PC3; HT_HG-U133A	GREB1L ATXN7L3B HKDC1 KIT KLHL22	2.62e-04	193	67	5	6678_UP
Drug	(1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Down 200; 11.8uM; PC3; HT_HG-U133A	ZNF155 RCHY1 ATXN7L3B OGA KLHL22	2.62e-04	193	67	5	3810_DN
Drug	Leflunomide [75706-12-6]; Up 200; 14.8uM; MCF7; HT_HG-U133A	CSF1R GPR68 TENM1 OGA KLHL22	2.62e-04	193	67	5	7238_UP
Drug	Cephalosporanic acid, 7-amino [957-68-6]; Down 200; 14.6uM; PC3; HT_HG-U133A	RAPSN PEG3 CASP1 OGA KLHL22	2.68e-04	194	67	5	4242_DN
Drug	DEANO	PDE2A CASP1 CARD16	2.76e-04	43	67	3	CID000163608
Drug	Gentamicine sulfate [1405-41-0]; Up 200; 2.6uM; MCF7; HT_HG-U133A	CLSTN3 THRB APC2 CASP1 OGA	2.81e-04	196	67	5	2245_UP
Drug	Nialamide [51-12-7]; Down 200; 13.4uM; PC3; HT_HG-U133A	CLSTN3 THRB CELSR2 RCHY1 PEG3	2.81e-04	196	67	5	3790_DN
Drug	Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; MCF7; HT_HG-U133A	GREB1L CLSTN3 CELSR2 CASP1 OGA	2.81e-04	196	67	5	1494_UP
Drug	CP-320650-01 [172079-28-6]; Down 200; 1uM; PC3; HT_HG-U133A	CLSTN3 ZNF155 CELSR2 SLITRK5 OGA	2.88e-04	197	67	5	3825_DN
Drug	Dydrogesterone [152-62-5]; Up 200; 12.8uM; PC3; HT_HG-U133A	CSF1R ZNF155 APC2 NR5A2 KIT	2.88e-04	197	67	5	4254_UP
Drug	Tranexamic acid [1197-18-8]; Up 200; 25.4uM; MCF7; HT_HG-U133A	GREB1L NELL2 THRB APC2 CASP1	2.88e-04	197	67	5	2248_UP
Drug	2-vinyl benzaldehyde	DNER CASP1 CARD16 DPP3	2.92e-04	108	67	4	CID000039391
Drug	Diclofenac sodium [15307-79-6]; Up 200; 12.6uM; PC3; HT_HG-U133A	CLSTN3 THRB CSF1R CELSR2 TENM1	2.95e-04	198	67	5	5861_UP
Drug	Lorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; MCF7; HT_HG-U133A	RELN ABL2 CSF1R ZNF155 NR5A2	2.95e-04	198	67	5	5254_UP
Drug	Napelline [5008-52-6]; Up 200; 11.2uM; PC3; HT_HG-U133A	CLSTN3 THRB RCHY1 APC2 KLHL22	2.95e-04	198	67	5	4486_UP
Drug	Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A	GREB1L RELN ZNF155 OGA KIT	2.95e-04	198	67	5	4745_UP
Drug	Glipizide [29094-61-9]; Up 200; 9uM; PC3; HT_HG-U133A	CLSTN3 CSF1R CASP1 KIT KLHL22	2.95e-04	198	67	5	6645_UP
Drug	(S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; MCF7; HT_HG-U133A	MBTPS2 GPR68 PEG3 CASP1 KIT	3.02e-04	199	67	5	6444_UP
Drug	Anabasine [494-52-0]; Down 200; 24.6uM; MCF7; HT_HG-U133A	ABL2 CSF1R MBTPS2 CASP1 KLHL22	3.02e-04	199	67	5	6074_DN
Drug	thiazepine	CASP1 CARD16	3.03e-04	9	67	2	CID012444276
Drug	Isatin Sulfonamide 29	CASP1 CARD16	3.03e-04	9	67	2	CID009821545
Drug	Ho Chi	CASP1 CARD16	3.03e-04	9	67	2	CID000128142
Drug	caprolactam	CASP1 CARD16	3.03e-04	9	67	2	CID000007768
Drug	Inhibitor 69b	CASP1 CARD16	3.03e-04	9	67	2	CID005327310
Drug	inhibitor 59	CASP1 CARD16	3.03e-04	9	67	2	CID005327305
Drug	Inhibitor 66a	CASP1 CARD16	3.03e-04	9	67	2	CID005327308
Drug	Inhibitor 64b	CASP1 CARD16	3.03e-04	9	67	2	CID005327307
Drug	AC1NS22C	CASP1 CARD16	3.03e-04	9	67	2	CID005327306
Drug	SA981	CASP1 CARD16	3.03e-04	9	67	2	CID000054805
Drug	3-Nitrobenzaldoxime	RCHY1 DNER CASP1 CARD16	3.58e-04	114	67	4	CID000219132
Drug	malonate	NOP9 CASP1 NUP133 CARD16 GRIN3B	3.78e-04	209	67	5	CID000000867
Drug	Dasatinib	ABL2 KIT	3.78e-04	10	67	2	DB01254
Drug	CGP 31362	CASP1 CARD16	3.78e-04	10	67	2	CID006540671
Drug	AC1L1EG5	THRB CASP1 CARD16	4.07e-04	49	67	3	CID000002779
Drug	R x A	CASP1 CARD16	4.61e-04	11	67	2	CID000010640
Drug	merbarone	CASP1 CARD16	4.61e-04	11	67	2	CID004990817
Disease	Geleophysic dysplasia	LTBP3 ADAMTSL2	4.91e-05	5	66	2	C3489726
Disease	Acromicric Dysplasia	LTBP3 ADAMTSL2	4.91e-05	5	66	2	C0265287
Disease	gastrointestinal stromal tumor (is_implicated_in)	CSF1R KIT	2.68e-04	11	66	2	DOID:9253 (is_implicated_in)
Disease	1-myristoyl-2-arachidonoyl-GPC (14:0/20:4) measurement	GREB1L RAPSN	3.21e-04	12	66	2	EFO_0800453
Disease	level of Phosphatidylcholine (16:1_18:1) in blood serum	GREB1L RAPSN	3.78e-04	13	66	2	OBA_2045082
Disease	CD209 antigen measurement	CELSR2 ADAMTSL2	4.41e-04	14	66	2	EFO_0008077
Disease	renal cell carcinoma (is_implicated_in)	THRB CSF1R KIT	5.04e-04	69	66	3	DOID:4450 (is_implicated_in)
Disease	Malignant neoplasm of breast	PDE2A NOP9 CSF1R OTOGL APC2 TENM1 NUP133 PLA2G4A KIT	6.23e-04	1074	66	9	C0006142
Disease	Inborn Errors of Metabolism	PLA2G4A ADAMTSL2	6.56e-04	17	66	2	C0025521
Disease	hyperglycemia (implicated_via_orthology)	HKDC1 PLA2G4A	6.56e-04	17	66	2	DOID:4195 (implicated_via_orthology)
Disease	sodium-coupled monocarboxylate transporter 1 measurement	RAPSN CELSR2	8.22e-04	19	66	2	EFO_0802076
Disease	lung adenocarcinoma (is_marker_for)	CSF1R ABCE1 NUF2	9.26e-04	85	66	3	DOID:3910 (is_marker_for)
Disease	Mammary Carcinoma, Human	PDE2A NOP9 CSF1R APC2 PLA2G4A KIT	1.14e-03	525	66	6	C4704874
Disease	Mammary Neoplasms, Human	PDE2A NOP9 CSF1R APC2 PLA2G4A KIT	1.14e-03	525	66	6	C1257931
Disease	Mammary Neoplasms	PDE2A NOP9 CSF1R APC2 PLA2G4A KIT	1.16e-03	527	66	6	C1458155
Disease	Breast Carcinoma	PDE2A NOP9 CSF1R APC2 PLA2G4A KIT	1.29e-03	538	66	6	C0678222
Disease	peptide measurement	ABL2 THRB PLA2G4A	1.89e-03	109	66	3	EFO_0010520
Disease	aortic stenosis	RAPSN CELSR2	2.20e-03	31	66	2	EFO_0000266

Protein segments in the cluster

Peptide	Gene	Start	Entry
EVIECLYACREGLDY	CLSTN3	541	Q9BQT9
LLDYCSGYVDCIPQT	ABL2	1116	P42684
IYVDLIEDSCLGFCF	ATXN7L3B	21	Q96GX2
IYCSDGEEYTVSSCV	ABITRAM	101	Q9NX38
TGDYCETEIDLCYSD	CELSR1	1356	Q9NYQ6
TGDYCETEVDLCYSR	CELSR2	1281	Q9HCU4
CYCVYKLTIGRDDSE	ARMCX6	21	Q7L4S7
ESKYCGLCDSIITIY	MTCH2	156	Q9Y6C9
VEETELYCGLCGESI	RAPSN	356	Q13702
YCDLICLDYDGNILD	EXOSC8	136	Q96B26
YLCELCLDDVLYART	DAB2IP	231	Q5VWQ8
CLIYYSLITIEDNGC	NUP133	366	Q8WUM0
LAAEVCDDFLVYCGD	NOP9	186	Q86U38
EEICLAECDIYSYNP	MAF1	156	Q9H063
CICKTGYIRIDDYSC	NELL2	466	Q99435
TLVITEYCCYGDLLN	KIT	666	P10721
EECTTSYLTLCNEYG	RPS6KC1	506	Q96S38
EEGECSYELEVESYL	FANCM	771	Q8IYD8
CLTYCDELSLYAVGS	DCAF12L2	311	Q5VW00
TCACVEYYGKALEVL	DDX55	276	Q8NHQ9
YEIYGDSVDCLPSCQ	NUF2	276	Q9BZD4
VYTYLLDGESQLVCE	PDE2A	81	O00408
CVRYDGVEVDDSYCD	ADAMTSL2	591	Q86TH1
YEECRAESVGLYLCL	DPP3	506	Q9NY33
EEIDELGYTLYCSLS	MIEF1	441	Q9NQG6
VTCSDLSYGDLLYEV	CRLF2	136	Q9HC73
DCYLNIGPEVAICYI	GREB1L	1816	Q9C091
FDVECGDEVLYCYEV	NAA40	126	Q86UY6
IYECEDCGLGFVDLT	PEG3	1106	Q9GZU2
CSVTDSCYAIELEYS	RELN	2386	P78509
SCYAIELEYSVDLGL	RELN	2391	P78509
CYGYCIDLLEKIAED	GRIN3A	576	Q8TCU5
LSVLDYLSDFICCLY	ABCE1	276	P61221
LCLTTPTEEAVYCFY	APC2	1496	O95996
VITEYCCYGDLLNFL	CSF1R	661	P07333
EVSCETEVYEGALLY	KLHL22	206	Q53GT1
ICITYICEEDSYLAG	CASP1	71	P29466
ESYVCRTLDCEAVYC	DCST1	656	Q5T197
YYDGNLLECVDVDEC	LTBP3	1026	Q9NS15
CLDTIAYEPQIGYCI	MBTPS2	296	O43462
RDLVNGYECVCLAEY	DNER	521	Q8NFT8
EECCYYINESGLVET	ERVFC1	471	P60507
ICITYICEEDSYLAE	CARD16	71	Q5EG05
EYLSGEVIATPCYTC	OTOGL	916	Q3ZCN5
ALYESGILDCATYVA	PLA2G4A	211	P47712
YISVGFLCCISVDRY	GPR68	106	Q15743
ADSLYEGRTISYECC	OR4C3	81	Q8NH37
YSYDEDLEELCPVCG	NR5A2	76	O00482
CYGYCIDLLERLAED	GRIN3B	476	O60391
QLYYKEITEACVGSC	TAF6	221	P49848
YYAVDEITISGRCQC	USH2A	506	O75445
TKGTCYLDQVEVSYC	SSPOP	5066	A2VEC9
TCAYDDPYCEVGVII	HKDC1	216	Q2TB90
YCFVLEDEDGICGYA	OGA	766	O60502
ASLVCQELGYSYVEL	RFC1	661	P35251
GLEAQYTCPICLEVY	RNF166	26	Q96A37
QYDVCAICLDEYEDG	RNF167	226	Q9H6Y7
EYDVCAICLDEYEDG	RNF13	236	O43567
VCYSLIDILLAYCYE	SHQ1	271	Q6PI26
LAEALVSVGYEYETC	TENM1	1096	Q9UKZ4
NTEEGIGICYAVCEY	MSH4	766	O15457
YLVYCTCSITVEENE	NOP2	511	P46087
CTVLEYCEGNDLDFY	TLK2	541	Q86UE8
CLYDLAKELGCSYTD	SPG11	1996	Q96JI7
SCAETIDYYGEICDN	SLITRK5	36	O94991
YIPSYLDKDELCVVC	THRB	96	P10828
TIGYGYRCVTEECSV	KCNJ16	131	Q9NPI9
YTCDECGKSICYISA	ZNF155	176	Q12901
EECSTLFGEYYCDIC	RCHY1	76	Q96PM5
SDCYIIHYIDDILCA	ERVK-19	191	Q9WJR5