Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessanimal organ morphogenesis

TGFB1 IGF1R DLC1 PRICKLE1 WNT3 INPPL1 ITGA6 LRP6 DLG1 CLDN5 TSHZ1 ATG9A GRHL3 SHROOM2 CCDC39 PLXNA1 TNFRSF11B AGTPBP1 HTT JHY DNAH11

1.23e-0812698121GO:0009887
GeneOntologyBiologicalProcesshead morphogenesis

TGFB1 PRICKLE1 WNT3 LRP6 CLDN5 CRISPLD1

3.27e-0848816GO:0060323
GeneOntologyBiologicalProcesshead development

TGFB1 IGF1R ATP7A DLC1 PRICKLE1 WNT3 LRP6 CLDN5 SHROOM2 CRISPLD1 HYDIN CCDC39 PLXNA1 AGTPBP1 HTT JHY EPHA7

8.10e-089198117GO:0060322
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

TGFB1 NPHP1 IGF1R ATP7A DLC1 PRICKLE1 LRP6 DLG1 GRHL3 CCDC39 PLXNA1 HTT JHY EPHA7

1.19e-076198114GO:0002009
GeneOntologyBiologicalProcessbody morphogenesis

TGFB1 PRICKLE1 WNT3 LRP6 CLDN5 CRISPLD1

1.90e-0764816GO:0010171
GeneOntologyBiologicalProcesstissue morphogenesis

TGFB1 NPHP1 IGF1R ATP7A DLC1 PRICKLE1 WNT3 LRP6 DLG1 GRHL3 CCDC39 PLXNA1 HTT JHY EPHA7

1.95e-077508115GO:0048729
GeneOntologyBiologicalProcessface morphogenesis

TGFB1 PRICKLE1 LRP6 CLDN5 CRISPLD1

5.53e-0741815GO:0060325
GeneOntologyBiologicalProcesscell junction organization

TGFB1 NPHP1 IGF1R DLC1 PRICKLE1 FRRS1L DNER ITGA6 SNX27 DLG1 DLG4 CLDN5 CHD4 MARVELD3 SHROOM2 EPHA7

1.01e-069748116GO:0034330
GeneOntologyBiologicalProcessface development

TGFB1 PRICKLE1 LRP6 CLDN5 CRISPLD1

4.85e-0663815GO:0060324
GeneOntologyBiologicalProcessregulation of AMPA glutamate receptor clustering

FRRS1L SNX27 DLG4

6.86e-0610813GO:1904717
GeneOntologyBiologicalProcessregulation of glutamate receptor clustering

FRRS1L SNX27 DLG4

6.86e-0610813GO:0106104
GeneOntologyBiologicalProcesscell junction assembly

NPHP1 DLC1 PRICKLE1 DNER ITGA6 DLG1 DLG4 CLDN5 CHD4 MARVELD3 EPHA7

1.35e-055698111GO:0034329
GeneOntologyBiologicalProcesscentral nervous system development

TGFB1 IGF1R ATP7A DLC1 WNT3 LRP6 GRHL3 SHROOM2 SHC3 HYDIN CCDC39 PLXNA1 AGTPBP1 HTT JHY EPHA7

1.41e-0511978116GO:0007417
GeneOntologyBiologicalProcessAMPA glutamate receptor clustering

FRRS1L SNX27 DLG4

2.06e-0514813GO:0097113
GeneOntologyBiologicalProcessglutamate receptor clustering

FRRS1L SNX27 DLG4

2.06e-0514813GO:0097688
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

ISLR2 RAP1GAP IGF1R ATP7A WNT3 INPPL1 ITGA6 LRP6 DLG4 PLD1 PLXNA1 HTT EPHA7

2.41e-058468113GO:0120035
GeneOntologyBiologicalProcessestablishment of planar polarity

NPHP1 LRP6 GRHL3 JHY

2.66e-0544814GO:0001736
GeneOntologyBiologicalProcessbrain development

IGF1R ATP7A DLC1 WNT3 LRP6 SHROOM2 HYDIN CCDC39 PLXNA1 AGTPBP1 HTT JHY EPHA7

2.82e-058598113GO:0007420
GeneOntologyBiologicalProcessestablishment of tissue polarity

NPHP1 LRP6 GRHL3 JHY

2.91e-0545814GO:0007164
GeneOntologyBiologicalProcessregulation of cell projection organization

ISLR2 RAP1GAP IGF1R ATP7A WNT3 INPPL1 ITGA6 LRP6 DLG4 PLD1 PLXNA1 HTT EPHA7

2.96e-058638113GO:0031344
GeneOntologyBiologicalProcesscamera-type eye development

TGFB1 NPHP1 LPCAT1 PRICKLE1 LRP6 DLG1 GRHL3 SHROOM2 AGTPBP1

4.41e-05426819GO:0043010
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

TGFB1 NPHP1 WASH6P RAP1GAP ATP7A DLC1 PRICKLE1 DLG1 DLG4 CLDN5 CHD4 PLD1 HTT EPHA7 SORL1

5.30e-0511898115GO:0044087
GeneOntologyBiologicalProcessregulation of establishment of planar polarity

LRP6 GRHL3 JHY

5.40e-0519813GO:0090175
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

RAP1GAP ATP7A PRICKLE1 PIERCE1 INPPL1 ITGA6 PLD1 HYDIN CCDC39 HTT JHY

6.01e-056708111GO:0120031
GeneOntologyBiologicalProcessregulation of animal organ morphogenesis

TGFB1 LRP6 GRHL3 TNFRSF11B JHY

7.31e-05110815GO:2000027
GeneOntologyBiologicalProcesscell projection assembly

RAP1GAP ATP7A PRICKLE1 PIERCE1 INPPL1 ITGA6 PLD1 HYDIN CCDC39 HTT JHY

7.33e-056858111GO:0030031
GeneOntologyBiologicalProcessregulation of anatomical structure morphogenesis

TGFB1 ISLR2 DDAH1 DLC1 WNT3 LRP6 DLG1 DLG4 CLDN5 GRHL3 PLXNA1 TNFRSF11B JHY EPHA7

8.05e-0510908114GO:0022603
GeneOntologyBiologicalProcessneural tube closure

TGFB1 DLC1 PRICKLE1 LRP6 GRHL3

8.30e-05113815GO:0001843
GeneOntologyBiologicalProcessneurotransmitter-gated ion channel clustering

FRRS1L SNX27 DLG4

8.51e-0522813GO:0072578
GeneOntologyBiologicalProcesstube closure

TGFB1 DLC1 PRICKLE1 LRP6 GRHL3

8.66e-05114815GO:0060606
GeneOntologyBiologicalProcessmorphogenesis of embryonic epithelium

TGFB1 DLC1 PRICKLE1 LRP6 GRHL3 HTT

1.03e-04190816GO:0016331
GeneOntologyBiologicalProcesseye development

TGFB1 NPHP1 LPCAT1 PRICKLE1 LRP6 DLG1 GRHL3 SHROOM2 AGTPBP1

1.10e-04480819GO:0001654
GeneOntologyBiologicalProcessprimary neural tube formation

TGFB1 DLC1 PRICKLE1 LRP6 GRHL3

1.10e-04120815GO:0014020
GeneOntologyBiologicalProcessendosome to plasma membrane protein transport

WASH6P SNX27 SORL1

1.11e-0424813GO:0099638
GeneOntologyBiologicalProcessvisual system development

TGFB1 NPHP1 LPCAT1 PRICKLE1 LRP6 DLG1 GRHL3 SHROOM2 AGTPBP1

1.15e-04483819GO:0150063
GeneOntologyBiologicalProcesshindbrain morphogenesis

ATP7A DLC1 LRP6 AGTPBP1

1.17e-0464814GO:0021575
GeneOntologyBiologicalProcesssensory system development

TGFB1 NPHP1 LPCAT1 PRICKLE1 LRP6 DLG1 GRHL3 SHROOM2 AGTPBP1

1.30e-04491819GO:0048880
GeneOntologyBiologicalProcesspositive regulation of cell projection organization

ISLR2 IGF1R ATP7A WNT3 ITGA6 LRP6 DLG4 PLXNA1 HTT

1.36e-04494819GO:0031346
GeneOntologyBiologicalProcesscellular component disassembly

TGFB1 DPP4 IGF1R PRICKLE1 PIK3C3 ADAMTS15 ATG9A SHROOM2 HTT DHX8

1.48e-046178110GO:0022411
GeneOntologyBiologicalProcessregulation of dephosphorylation

TGFB1 DLC1 CMYA5 CHRM5 HTT

1.49e-04128815GO:0035303
GeneOntologyBiologicalProcesspositive regulation of AMPA glutamate receptor clustering

SNX27 DLG4

1.51e-045812GO:1904719
GeneOntologyBiologicalProcesspositive regulation of postsynaptic membrane organization

SNX27 DLG4

1.51e-045812GO:1901628
GeneOntologyBiologicalProcessepithelium development

TGFB1 NPHP1 IGF1R ATP7A DLC1 PRICKLE1 LRP6 DLG1 CLDN5 GRHL3 HYDIN CCDC39 PLXNA1 HTT JHY EPHA7

1.63e-0414698116GO:0060429
GeneOntologyBiologicalProcessdevelopmental growth involved in morphogenesis

TGFB1 ISLR2 PRICKLE1 WNT3 LRP6 PLXNA1 EPHA7

1.74e-04299817GO:0060560
GeneOntologyBiologicalProcessneural tube formation

TGFB1 DLC1 PRICKLE1 LRP6 GRHL3

1.85e-04134815GO:0001841
GeneOntologyBiologicalProcessmorphogenesis of a polarized epithelium

NPHP1 LRP6 GRHL3 JHY

1.96e-0473814GO:0001738
GeneOntologyBiologicalProcessregulation of receptor clustering

FRRS1L SNX27 DLG4

1.98e-0429813GO:1903909
GeneOntologyBiologicalProcessregulation of cell junction assembly

NPHP1 DLC1 PRICKLE1 DLG4 CLDN5 CHD4 EPHA7

2.13e-04309817GO:1901888
GeneOntologyBiologicalProcesspattern specification process

PRICKLE1 PIERCE1 WNT3 LRP6 TSHZ1 GRHL3 CCDC39 HTT DNAH11

2.18e-04526819GO:0007389
GeneOntologyBiologicalProcessestablishment of blood-retinal barrier

LRP6 CLDN5

2.26e-046812GO:1990963
GeneOntologyBiologicalProcesspostsynapse organization

IGF1R PRICKLE1 FRRS1L SNX27 DLG1 DLG4 EPHA7

2.31e-04313817GO:0099173
GeneOntologyBiologicalProcessepithelial tube morphogenesis

TGFB1 DLC1 PRICKLE1 LRP6 DLG1 GRHL3 CCDC39 EPHA7

2.47e-04421818GO:0060562
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

TGFB1 NPHP1 ISLR2 RAP1GAP IGF1R ATP7A WNT3 ITGA6 SNX27 LRP6 DLG1 DLG4 CLDN5 PLXNA1 HTT

2.47e-0413668115GO:0051130
GeneOntologyBiologicalProcessheart morphogenesis

TGFB1 DLC1 PRICKLE1 LRP6 CLDN5 CCDC39 DNAH11

2.69e-04321817GO:0003007
GeneOntologyBiologicalProcessbicellular tight junction assembly

NPHP1 DLG1 CLDN5 MARVELD3

2.92e-0481814GO:0070830
GeneOntologyBiologicalProcessregulation of postsynaptic membrane organization

SNX27 DLG4

3.16e-047812GO:1901626
GeneOntologyBiologicalProcessestablishment of left/right asymmetry

PIERCE1 CCDC39

3.16e-047812GO:0061966
GeneOntologyBiologicalProcessreceptor clustering

FRRS1L SNX27 DLG1 DLG4

3.20e-0483814GO:0043113
GeneOntologyBiologicalProcessregulation of phosphate metabolic process

TGFB1 LPCAT1 FNDC1 IGF1R DLC1 ITGA6 LRP6 DLG1 DLG4 CMYA5 HSPA4 CHRM5 HTT EEF1A1 EPHA7

3.77e-0414218115GO:0019220
GeneOntologyBiologicalProcessregulation of phosphorus metabolic process

TGFB1 LPCAT1 FNDC1 IGF1R DLC1 ITGA6 LRP6 DLG1 DLG4 CMYA5 HSPA4 CHRM5 HTT EEF1A1 EPHA7

3.83e-0414238115GO:0051174
GeneOntologyBiologicalProcesstight junction assembly

NPHP1 DLG1 CLDN5 MARVELD3

4.01e-0488814GO:0120192
GeneOntologyBiologicalProcessembryonic epithelial tube formation

TGFB1 DLC1 PRICKLE1 LRP6 GRHL3

4.09e-04159815GO:0001838
GeneOntologyBiologicalProcesscell-cell junction organization

TGFB1 NPHP1 DLG1 CLDN5 MARVELD3 SHROOM2

4.16e-04246816GO:0045216
GeneOntologyBiologicalProcessregulation of microvillus assembly

RAP1GAP PLD1

4.20e-048812GO:0032534
GeneOntologyBiologicalProcessdephosphorylation

TGFB1 DLC1 INPPL1 STYXL2 CMYA5 CHRM5 HTT

4.30e-04347817GO:0016311
GeneOntologyBiologicalProcessapical junction assembly

NPHP1 DLG1 CLDN5 MARVELD3

4.36e-0490814GO:0043297
GeneOntologyBiologicalProcessaxis elongation

TGFB1 PRICKLE1 LRP6

4.46e-0438813GO:0003401
GeneOntologyBiologicalProcessembryonic morphogenesis

TGFB1 DLC1 PRICKLE1 WNT3 LRP6 DLG1 TSHZ1 GRHL3 CCDC39 HTT

4.70e-047138110GO:0048598
GeneOntologyBiologicalProcesstight junction organization

NPHP1 DLG1 CLDN5 MARVELD3

5.15e-0494814GO:0120193
GeneOntologyBiologicalProcessestablishment or maintenance of cell polarity

IGF1R PRICKLE1 SNX27 DLG1 DLG4 HTT

5.25e-04257816GO:0007163
GeneOntologyBiologicalProcesscitrulline metabolic process

DDAH1 HTT

5.39e-049812GO:0000052
GeneOntologyBiologicalProcesspositive regulation of bicellular tight junction assembly

NPHP1 CLDN5

5.39e-049812GO:1903348
GeneOntologyBiologicalProcessmaintenance of postsynaptic density structure

PRICKLE1 DLG1

5.39e-049812GO:0099562
GeneOntologyBiologicalProcesssensory organ development

TGFB1 NPHP1 LPCAT1 PRICKLE1 LRP6 DLG1 TSHZ1 GRHL3 SHROOM2 AGTPBP1

5.64e-047308110GO:0007423
GeneOntologyBiologicalProcessregionalization

PRICKLE1 PIERCE1 WNT3 LRP6 TSHZ1 CCDC39 HTT DNAH11

5.74e-04478818GO:0003002
GeneOntologyBiologicalProcessepithelial tube formation

TGFB1 DLC1 PRICKLE1 LRP6 GRHL3

6.00e-04173815GO:0072175
GeneOntologyBiologicalProcessregulation of neuron projection development

ISLR2 IGF1R WNT3 INPPL1 ITGA6 LRP6 DLG4 PLXNA1 EPHA7

6.55e-04612819GO:0010975
GeneOntologyBiologicalProcessnegative regulation of extracellular matrix disassembly

TGFB1 DPP4

6.72e-0410812GO:0010716
GeneOntologyBiologicalProcesscellular component maintenance

IGF1R PRICKLE1 DLG1 SHROOM2

6.75e-04101814GO:0043954
GeneOntologyBiologicalProcessmicrotubule-based movement

PIERCE1 DNAI7 HYDIN CCDC39 AGTPBP1 HTT JHY DNAH11

7.03e-04493818GO:0007018
GeneOntologyBiologicalProcesscell morphogenesis

TGFB1 ISLR2 IGF1R ATP7A DLC1 PRICKLE1 WNT3 LRP6 DLG1 DLG4 SHROOM2 PLXNA1 EPHA7

7.30e-0411948113GO:0000902
GeneOntologyBiologicalProcessroof of mouth development

LRP6 DLG1 CLDN5 TSHZ1

7.53e-04104814GO:0060021
GeneOntologyBiologicalProcessregulation of nervous system development

TGFB1 ISLR2 WNT3 LRP6 DLG1 DLG4 PLXNA1 EPHA7 SORL1

7.60e-04625819GO:0051960
GeneOntologyBiologicalProcesspositive regulation by host of viral genome replication

PIK3C3 EEF1A1

8.19e-0411812GO:0044829
GeneOntologyBiologicalProcessnail development

PRICKLE1 ITGA6

8.19e-0411812GO:0035878
GeneOntologyBiologicalProcessmicrotubule-based process

WASH6P CDC42BPA PRICKLE1 PIERCE1 DLG1 DNAI7 HYDIN CCDC39 AGTPBP1 HTT JHY DNAH11

8.35e-0410588112GO:0007017
GeneOntologyBiologicalProcessodontogenesis of dentin-containing tooth

TGFB1 ITGA6 LRP6 TNFRSF11B

8.38e-04107814GO:0042475
GeneOntologyBiologicalProcesstube formation

TGFB1 DLC1 PRICKLE1 LRP6 GRHL3

8.52e-04187815GO:0035148
GeneOntologyBiologicalProcessaxoneme assembly

PIERCE1 HYDIN CCDC39 JHY

8.98e-04109814GO:0035082
GeneOntologyBiologicalProcesshindlimb morphogenesis

ATP7A WNT3 LRP6

9.44e-0449813GO:0035137
GeneOntologyBiologicalProcessresponse to nutrient

TGFB1 IGF1R LRP6 PLD1 TNFRSF11B

9.59e-04192815GO:0007584
GeneOntologyBiologicalProcesscell-cell adhesion

TGFB1 NPHP1 DPP4 RHOH RAP1GAP PRICKLE1 ITGA6 LRP6 DLG1 DLG4 CLDN5 EPHA7

9.75e-0410778112GO:0098609
GeneOntologyBiologicalProcessprotein localization to organelle

TGFB1 TAF8 PRICKLE1 PIK3C3 DLG1 DLG4 ATG9A HSPA4 CCDC39 HTT SORL1 DNAH11

1.09e-0310918112GO:0033365
GeneOntologyBiologicalProcessprimitive streak formation

PRICKLE1 LRP6

1.16e-0313812GO:0090009
GeneOntologyBiologicalProcesscellular response to insulin-like growth factor stimulus

TGFB1 IGF1R

1.16e-0313812GO:1990314
GeneOntologyBiologicalProcessactin cytoskeleton organization

TGFB1 NPHP1 WASH6P RHOH DLC1 CDC42BPA INPPL1 DLG1 GRHL3 SHROOM2

1.17e-038038110GO:0030036
GeneOntologyBiologicalProcessneural tube development

TGFB1 DLC1 PRICKLE1 LRP6 GRHL3

1.20e-03202815GO:0021915
GeneOntologyBiologicalProcessWnt signaling pathway, planar cell polarity pathway

PRICKLE1 LRP6 GRHL3

1.32e-0355813GO:0060071
GeneOntologyBiologicalProcessnegative regulation of macrophage cytokine production

TGFB1 ATG9A

1.34e-0314812GO:0010936
GeneOntologyBiologicalProcessprotein localization to cell periphery

TGFB1 WASH6P SNX27 LRP6 DLG1 DLG4 SORL1

1.35e-03422817GO:1990778
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

PIK3C3 PIERCE1 DLG4 DNAI7 HYDIN CCDC39 AGTPBP1 HTT DNAH11

5.14e-06317849GO:0032838
GeneOntologyCellularComponentcytoplasmic region

PIK3C3 PIERCE1 DLG4 DNAI7 HYDIN CCDC39 AGTPBP1 HTT DNAH11

1.42e-05360849GO:0099568
GeneOntologyCellularComponentcytoplasmic vesicle membrane

WASH6P LPCAT1 ATP7A SYTL4 PIK3C3 WNT3 SNX27 LRP6 DLG1 DLG4 ATG9A PLD1 FRMPD3 HTT CYB5R1 SORL1

5.59e-0513078416GO:0030659
GeneOntologyCellularComponentvesicle membrane

WASH6P LPCAT1 ATP7A SYTL4 PIK3C3 WNT3 SNX27 LRP6 DLG1 DLG4 ATG9A PLD1 FRMPD3 HTT CYB5R1 SORL1

6.57e-0513258416GO:0012506
GeneOntologyCellularComponentcell-cell junction

NPHP1 DPP4 FNDC1 CDC42BPA ITGA6 DLG1 DLG4 CLDN5 MARVELD3 SHROOM2

1.27e-045918410GO:0005911
GeneOntologyCellularComponentcortical cytoskeleton

DLC1 DLG4 CLDN5 SHROOM2 EEF1A1

1.73e-04129845GO:0030863
GeneOntologyCellularComponentcell leading edge

WASH6P DPP4 ATP7A DLC1 CDC42BPA DPP9 INPPL1 PLD1 EEF1A1

1.79e-04500849GO:0031252
GeneOntologyCellularComponentbicellular tight junction

NPHP1 DLG1 CLDN5 MARVELD3 SHROOM2

1.86e-04131845GO:0005923
GeneOntologyCellularComponentaxoneme

PIK3C3 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.88e-04207846GO:0005930
GeneOntologyCellularComponentciliary plasm

PIK3C3 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.93e-04208846GO:0097014
GeneOntologyCellularComponenttight junction

NPHP1 DLG1 CLDN5 MARVELD3 SHROOM2

2.45e-04139845GO:0070160
GeneOntologyCellularComponentapical junction complex

NPHP1 DLG1 CLDN5 MARVELD3 SHROOM2

4.42e-04158845GO:0043296
GeneOntologyCellularComponentneuronal cell body

TGFB1 RAP1GAP IGF1R ATP7A DNER LRP6 DLG1 SHROOM2 HTT EPHA7 SORL1

5.02e-048358411GO:0043025
GeneOntologyCellularComponentlate endosome

WASH6P ATP7A PIK3C3 ATG9A PLD1 HTT SORL1

5.04e-04348847GO:0005770
GeneOntologyCellularComponentcortical actin cytoskeleton

DLC1 CLDN5 SHROOM2 EEF1A1

5.40e-0493844GO:0030864
GeneOntologyCellularComponentplatelet alpha granule

TGFB1 SYTL4 F8 CYB5R1

5.40e-0493844GO:0031091
GeneOntologyCellularComponentearly endosome

WASH6P RAP1GAP ATP7A DNER SNX27 LRP6 HTT SORL1

7.00e-04481848GO:0005769
GeneOntologyCellularComponentactin-based cell projection

TGFB1 WASH6P ATP7A INPPL1 ITGA6 DLG1

8.95e-04278846GO:0098858
GeneOntologyCellularComponentimmunological synapse

RHOH SNX27 DLG1

1.01e-0349843GO:0001772
GeneOntologyCellularComponentsomatodendritic compartment

TGFB1 RAP1GAP IGF1R ATP7A DNER LRP6 DLG1 DLG4 SHROOM2 CHRM5 HTT EPHA7 SORL1

1.18e-0312288413GO:0036477
GeneOntologyCellularComponentcell body

TGFB1 RAP1GAP IGF1R ATP7A DNER LRP6 DLG1 SHROOM2 HTT EPHA7 SORL1

1.20e-039298411GO:0044297
GeneOntologyCellularComponentsecretory vesicle

TGFB1 LPCAT1 ATP7A MAN2B1 SYTL4 DLG1 DLG4 ATG9A PLD1 FRMPD3 F8 CYB5R1 EEF1A1

1.35e-0312468413GO:0099503
GeneOntologyCellularComponentautophagosome

WASH6P PIK3C3 ATG9A HTT

1.36e-03119844GO:0005776
GeneOntologyCellularComponentglutamatergic synapse

IGF1R PRICKLE1 PIK3C3 SNX27 DLG1 DLG4 CHD4 PLXNA1 HTT EPHA7

1.59e-038178410GO:0098978
GeneOntologyCellularComponentWASH complex

WASH6P SNX27

1.62e-0315842GO:0071203
GeneOntologyCellularComponentearly endosome membrane

WASH6P ATP7A SNX27 LRP6 SORL1

1.65e-03212845GO:0031901
GeneOntologyCellularComponentadherens junction

NPHP1 ITGA6 DLG1 DLG4 SHROOM2

1.65e-03212845GO:0005912
GeneOntologyCellularComponentanchoring junction

NPHP1 DPP4 FNDC1 DLC1 CDC42BPA ITGA6 DLG1 DLG4 CLDN5 MARVELD3 SHROOM2

1.78e-039768411GO:0070161
GeneOntologyCellularComponentWnt signalosome

WNT3 LRP6

1.85e-0316842GO:1990909
GeneOntologyCellularComponentparanode region of axon

DLG1 CLDN5

2.09e-0317842GO:0033270
GeneOntologyCellularComponentplatelet alpha granule membrane

SYTL4 CYB5R1

2.09e-0317842GO:0031092
GeneOntologyCellularComponentlamellipodium

WASH6P DPP4 CDC42BPA INPPL1 PLD1

2.35e-03230845GO:0030027
GeneOntologyCellularComponentendosome

WASH6P RAP1GAP ATP7A SYTL4 PIK3C3 DNER SNX27 LRP6 ATG9A PLD1 HTT SORL1

2.37e-0311678412GO:0005768
GeneOntologyCellularComponentpostsynapse

IGF1R ATP7A PRICKLE1 PIK3C3 FRRS1L SNX27 DLG1 DLG4 CHRM5 HTT EPHA7

2.48e-0310188411GO:0098794
GeneOntologyCellularComponentapical plasma membrane

DPP4 ATP7A SYTL4 DLG1 SI PLD1 SHROOM2

3.45e-03487847GO:0016324
GeneOntologyCellularComponentcell cortex

WASH6P DLC1 DLG4 CLDN5 SHROOM2 EEF1A1

3.82e-03371846GO:0005938
GeneOntologyCellularComponentendocytic vesicle

DPP4 ATP7A PIK3C3 WNT3 DLG4 PLD1

4.51e-03384846GO:0030139
GeneOntologyCellularComponentpostsynaptic endosome

PIK3C3 SNX27

4.87e-0326842GO:0098845
GeneOntologyCellularComponentmain axon

DLG1 DLG4 CLDN5

5.54e-0389843GO:0044304
MousePhenoabnormal respiratory motile cilium physiology

PIERCE1 HYDIN CCDC39 DNAH11

1.39e-0529724MP:0011055
MousePhenolethality during fetal growth through weaning, complete penetrance

TGFB1 LPCAT1 IGF1R ATP7A DPP9 PRICKLE1 INPPL1 ITGA6 SNX27 LRP6 DLG1 CLDN5 TSHZ1 CHD4 ATG9A GRHL3 HYDIN CCDC39 HTT

1.53e-0512697219MP:0011111
MousePhenoright-sided stomach

PIERCE1 C2orf74 CCDC39 DNAH11

1.83e-0531724MP:0010808
MousePhenoabnormal stomach position or orientation

PIERCE1 C2orf74 CCDC39 DNAH11

3.36e-0536724MP:0010807
MousePhenoabnormal craniofacial morphology

TGFB1 IGF1R DLC1 DPP9 PRICKLE1 INPPL1 ITGA6 SNX27 LRP6 DLG1 TSHZ1 GRHL3 HYDIN CCDC39 TNFRSF11B HTT JHY SORL1 DNAH11

4.55e-0513727219MP:0000428
MousePhenocraniofacial phenotype

TGFB1 IGF1R DLC1 DPP9 PRICKLE1 INPPL1 ITGA6 SNX27 LRP6 DLG1 TSHZ1 GRHL3 HYDIN CCDC39 TNFRSF11B HTT JHY SORL1 DNAH11

4.55e-0513727219MP:0005382
MousePhenoabdominal situs ambiguus

C2orf74 CCDC39 DNAH11

6.99e-0516723MP:0011250
MousePhenoabnormal primitive streak morphology

DDX59 PRICKLE1 PIK3C3 PIERCE1 WNT3 HTT DNAH11

7.65e-05201727MP:0002231
MousePhenoblind uterus

DLG1 TNFRSF11B

7.82e-053722MP:0009084
MousePhenoabnormal extraembryonic endoderm formation

PRICKLE1 WNT3 HTT

1.01e-0418723MP:0001724
MousePhenoabnormal axial skeleton morphology

TGFB1 PRSS35 ZNF106 IGF1R ATP7A PRICKLE1 LRP6 DLG1 TSHZ1 MARVELD3 C2orf74 RAD54L2 GRHL3 HYDIN CCDC39 TNFRSF11B HTT JHY DNAH11

1.04e-0414587219MP:0002114
MousePhenoabnormal motile cilium physiology

PIERCE1 HYDIN CCDC39 DNAH11

1.35e-0451724MP:0013209
MousePhenoabnormal respiratory epithelium physiology

PIERCE1 HYDIN CCDC39 DNAH11

1.35e-0451724MP:0014200
MousePhenodextrocardia

PIERCE1 C2orf74 CCDC39 DNAH11

1.35e-0451724MP:0000644
MousePhenoabnormal cilium physiology

PIERCE1 HYDIN CCDC39 DNAH11

1.57e-0453724MP:0013208
MousePhenoabdominal situs abnormality

C2orf74 CCDC39 DNAH11

1.63e-0421723MP:0031284
MousePhenoabnormal brainstem morphology

IGF1R ATP7A MAN2B1 LRP6 HYDIN AGTPBP1 HTT

1.63e-04227727MP:0005277
MousePhenoabnormal germ layer morphology

PRICKLE1 PIK3C3 PIERCE1 WNT3 LRP6 GRHL3

1.77e-04161726MP:0014138
MousePhenoabnormal digestive organ placement

PIERCE1 C2orf74 CCDC39 DNAH11

2.08e-0457724MP:0003283
MousePhenositus inversus totalis

PIERCE1 CCDC39 DNAH11

2.15e-0423723MP:0011252
MousePhenoabnormal telencephalon morphology

ISLR2 ATP7A MAN2B1 PRICKLE1 ITGA6 LRP6 DLG4 TSHZ1 HYDIN CCDC39 AGTPBP1 HTT JHY

2.27e-048127213MP:0000787
MousePhenoperinatal lethality, complete penetrance

LPCAT1 IGF1R ATP7A DPP9 ITGA6 LRP6 DLG1 CLDN5 TSHZ1 ATG9A GRHL3 HTT

2.56e-047127212MP:0011089
MousePhenospina bifida cystica

LRP6 GRHL3

2.59e-045722MP:0012547
MousePhenoabnormal forebrain morphology

ISLR2 ATP7A DLC1 MAN2B1 PRICKLE1 SYTL4 ITGA6 LRP6 DLG4 TSHZ1 HYDIN CCDC39 AGTPBP1 HTT JHY

3.07e-0410727215MP:0000783
MousePhenoabnormal primitive node morphology

DDX59 PIERCE1 WNT3 HTT DNAH11

3.37e-04117725MP:0004066
MousePhenoabnormal inferior vena cava morphology

PIERCE1 C2orf74 CCDC39 DNAH11

4.11e-0468724MP:0006063
MousePhenopostnatal lethality, complete penetrance

TGFB1 ATP7A DPP9 PRICKLE1 INPPL1 SNX27 CHD4 HYDIN CCDC39

4.45e-04445729MP:0011085
MousePhenoabnormal brain ependyma motile cilium morphology

HYDIN CCDC39 JHY

4.81e-0430723MP:0011056
MousePhenoright-sided isomerism

PIERCE1 CCDC39 DNAH11

4.81e-0430723MP:0000508
MousePhenoabnormal mesoderm morphology

PRICKLE1 PIK3C3 PIERCE1 WNT3 LRP6

4.92e-04127725MP:0014141
MousePhenodisorganized embryonic tissue

PIK3C3 WNT3 HTT

5.31e-0431723MP:0003988
MousePhenoleft pulmonary isomerism

PIERCE1 CCDC39 DNAH11

5.31e-0431723MP:0003178
MousePhenoperinatal lethality

ISLR2 LPCAT1 IGF1R ATP7A DPP9 ITGA6 LRP6 DLG1 CLDN5 TSHZ1 CHD4 ATG9A GRHL3 HTT DNAH11

5.38e-0411307215MP:0002081
MousePhenoabnormal globus pallidus morphology

MAN2B1 HTT

5.40e-047722MP:0004081
MousePhenosuperior-inferior ventricles

CCDC39 DNAH11

5.40e-047722MP:0011254
MousePhenoabnormal heart position or orientation

PIERCE1 C2orf74 CCDC39 DNAH11

5.67e-0474724MP:0006065
MousePhenoabnormal olfactory bulb morphology

TSHZ1 HYDIN CCDC39 AGTPBP1 HTT

6.07e-04133725MP:0000819
MousePhenoabnormal vertebral column morphology

TGFB1 PRSS35 ZNF106 ATP7A PRICKLE1 LRP6 TSHZ1 MARVELD3 C2orf74 GRHL3 HYDIN DNAH11

6.32e-047877212MP:0004703
MousePhenoabnormal ependyma motile cilium morphology

HYDIN CCDC39 JHY

6.40e-0433723MP:0011059
MousePhenoabnormal respiratory system morphology

TGFB1 DPP4 LPCAT1 IGF1R ATP7A PRICKLE1 PIERCE1 LRP6 DLG1 TSHZ1 DNAI7 HYDIN CCDC39 DNAH11

6.54e-0410277214MP:0002132
MousePhenoabnormal vena cava morphology

PIERCE1 C2orf74 CCDC39 DNAH11

6.59e-0477724MP:0006062
MousePhenoembryonic lethality before implantation, incomplete penetrance

DDAH1 LRP6 DHX8

6.99e-0434723MP:0011104
MousePhenoleft-sided isomerism

PIERCE1 CCDC39 DNAH11

6.99e-0434723MP:0000542
MousePhenoleft atrial isomerism

CCDC39 DNAH11

7.18e-048722MP:0008461
MousePhenoabnormal cranium morphology

TGFB1 IGF1R PRICKLE1 LRP6 DLG1 TSHZ1 HYDIN CCDC39 TNFRSF11B HTT JHY DNAH11

8.41e-048137212MP:0000438
MousePhenoabnormal brain ependyma morphology

HYDIN CCDC39 JHY

8.98e-0437723MP:0010152
MousePhenoenlarged lateral ventricles

PRICKLE1 CCDC39 HTT JHY

9.15e-0484724MP:0008535
MousePhenodouble outlet right ventricle, ventricular defect committed to aorta

PRICKLE1 DNAH11

9.20e-049722MP:0011666
MousePhenoabdominal situs inversus

CCDC39 DNAH11

9.20e-049722MP:0011249
MousePhenodomed cranium

DLG1 HYDIN HTT JHY

9.56e-0485724MP:0000440
MousePhenoabnormal craniofacial bone morphology

TGFB1 IGF1R PRICKLE1 LRP6 DLG1 TSHZ1 HYDIN CCDC39 TNFRSF11B HTT JHY DNAH11

9.76e-048277212MP:0002116
MousePhenoabnormal olfactory lobe morphology

TSHZ1 HYDIN CCDC39 AGTPBP1 HTT

1.01e-03149725MP:0009944
DomainMAGUK_N_PEST

DLG1 DLG4

1.08e-044802PF10608
DomainPDZ_assoc

DLG1 DLG4

1.08e-044802PF10600
DomainDLG1_PEST_dom

DLG1 DLG4

1.08e-044802IPR019590
DomainPDZ_assoc

DLG1 DLG4

1.08e-044802IPR019583
DomainMAGUK_N_PEST

DLG1 DLG4

1.08e-044802SM01277
DomainDLG1

DLG1 DLG4

1.08e-044802IPR016313
DomainFN3

FNDC1 IGF1R IL20RA CMYA5 EPHA7 SORL1

2.12e-04199806PS50853
Domain-

DPP4 DPP9

2.69e-0468022.140.10.30
DomainDPPIV_N

DPP4 DPP9

2.69e-046802PF00930
DomainPeptidase_S9B_N

DPP4 DPP9

2.69e-046802IPR002469
DomainFN3_dom

FNDC1 IGF1R IL20RA CMYA5 EPHA7 SORL1

2.76e-04209806IPR003961
DomainPDZ

SNX27 DLG1 DLG4 FRMPD3 SHROOM2

3.49e-04141805PF00595
DomainPDZ

SNX27 DLG1 DLG4 FRMPD3 SHROOM2

4.35e-04148805SM00228
Domain-

SNX27 DLG1 DLG4 FRMPD3 SHROOM2

4.63e-041508052.30.42.10
DomainPDZ

SNX27 DLG1 DLG4 FRMPD3 SHROOM2

4.77e-04151805PS50106
DomainPDZ

SNX27 DLG1 DLG4 FRMPD3 SHROOM2

4.92e-04152805IPR001478
Domainfn3

FNDC1 IGF1R CMYA5 EPHA7 SORL1

6.57e-04162805PF00041
DomainSAM_2

DLC1 INPPL1 EPHA7

8.25e-0443803PF07647
DomainPeptidase_S9

DPP4 DPP9

9.72e-0411802PF00326
DomainPeptidase_S9

DPP4 DPP9

9.72e-0411802IPR001375
DomainHelicase_C

DDX59 CHD4 RAD54L2 DHX8

1.15e-03107804PF00271
DomainHELICc

DDX59 CHD4 RAD54L2 DHX8

1.15e-03107804SM00490
DomainFN3

FNDC1 IGF1R CMYA5 EPHA7 SORL1

1.19e-03185805SM00060
DomainHelicase_C

DDX59 CHD4 RAD54L2 DHX8

1.19e-03108804IPR001650
DomainHELICASE_CTER

DDX59 CHD4 RAD54L2 DHX8

1.23e-03109804PS51194
DomainHELICASE_ATP_BIND_1

DDX59 CHD4 RAD54L2 DHX8

1.23e-03109804PS51192
DomainDEXDc

DDX59 CHD4 RAD54L2 DHX8

1.23e-03109804SM00487
DomainHelicase_ATP-bd

DDX59 CHD4 RAD54L2 DHX8

1.28e-03110804IPR014001
Domain-

RHOH DDX59 DLG1 DLG4 CHD4 RAD54L2 HYDIN DHX8 EEF1A1 DNAH11

1.28e-0374680103.40.50.300
DomainuDENN

DENND2C DENND2D

1.59e-0314802SM00800
DomainLdl_recept_b

LRP6 SORL1

1.59e-0314802PF00058
DomainLDLRB

LRP6 SORL1

1.59e-0314802PS51120
Domain-

DPP4 DPP9 BAAT ABHD3

1.71e-031198043.40.50.1820
DomainAB_hydrolase

DPP4 DPP9 BAAT ABHD3

1.71e-03119804IPR029058
DomainuDENN

DENND2C DENND2D

1.83e-0315802PF03456
DomainLY

LRP6 SORL1

1.83e-0315802SM00135
DomainLDLR_classB_rpt

LRP6 SORL1

1.83e-0315802IPR000033
Domain-

ISLR2 FNDC1 IGF1R IL20RA CMYA5 LY9 PLXNA1 EPHA7 SORL1

2.08e-036638092.60.40.10
DomainUDENN

DENND2C DENND2D

2.09e-0316802PS50946
DomainDDENN

DENND2C DENND2D

2.09e-0316802PS50947
DomainDENN

DENND2C DENND2D

2.09e-0316802SM00799
DomainGuanylate_kinase_CS

DLG1 DLG4

2.09e-0316802IPR020590
DomaindDENN

DENND2C DENND2D

2.09e-0316802SM00801
DomainDENN

DENND2C DENND2D

2.09e-0316802PF02141
DomaindDENN_dom

DENND2C DENND2D

2.09e-0316802IPR005112
DomainuDENN_dom

DENND2C DENND2D

2.09e-0316802IPR005113
DomaindDENN

DENND2C DENND2D

2.09e-0316802PF03455
DomainDENN

DENND2C DENND2D

2.09e-0316802PS50211
DomainDENN_dom

DENND2C DENND2D

2.09e-0316802IPR001194
DomainGal_mutarotase_SF_dom

MAN2B1 SI

2.36e-0317802IPR011013
DomainIg-like_fold

ISLR2 FNDC1 IGF1R IL20RA CMYA5 LY9 PLXNA1 EPHA7 SORL1

3.17e-03706809IPR013783
DomainP-loop_NTPase

RHOH DDX59 DLG1 DLG4 CHD4 RAD54L2 HYDIN DHX8 EEF1A1 DNAH11

3.27e-038488010IPR027417
DomainMAGE_N

MAGEA1 MAGEA11

3.27e-0320802SM01392
DomainMAGE_N

MAGEA1 MAGEA11

3.96e-0322802PF12440
DomainMAGE_N

MAGEA1 MAGEA11

3.96e-0322802IPR021072
DomainGUANYLATE_KINASE_2

DLG1 DLG4

4.32e-0323802PS50052
DomainGUANYLATE_KINASE_1

DLG1 DLG4

4.32e-0323802PS00856
DomainEphrin_rec_like

TNFRSF11B EPHA7

5.10e-0325802SM01411
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

TGFB1 MAGEA1 RAP1GAP ATP7A DLC1 SYTL4 LRP6 DLG4 CHD4 MARVELD3 DENND2D ATG9A CRISPLD1 HYDIN

2.51e-061293841415342556
Pubmed

The SAM domain of the RhoGAP DLC1 binds EF1A1 to regulate cell migration.

DLC1 EEF1A1

5.76e-06284219158340
Pubmed

Igf1r as a therapeutic target in a mouse model of basal-like breast cancer.

IGF1R EEF1A1

5.76e-06284219174523
Pubmed

Exercise blood pressure response is related to asymmetric dimethylarginine and osteoprotegerin in hypertension.

DDAH1 TNFRSF11B

5.76e-06284221975354
Pubmed

[Expression and significance of TGF-beta1 and HSP70 in human laryngeal squamous cell carcinoma].

TGFB1 HSPA4

5.76e-06284217802821
Pubmed

Intragenic integration in DLC1 sustains factor VIII expression in primary human cells without insertional oncogenicity.

DLC1 F8

5.76e-06284224553346
Pubmed

[TGF-beta and HSP70 expression in human skin fibroblasts after ultraviolet B irradiation].

TGFB1 HSPA4

5.76e-06284221179807
Pubmed

Interaction between SAP97 and PSD-95, two Maguk proteins involved in synaptic trafficking of AMPA receptors.

DLG1 DLG4

5.76e-06284216332687
Pubmed

Polyglutamine-expanded huntingtin promotes sensitization of N-methyl-D-aspartate receptors via post-synaptic density 95.

DLG4 HTT

5.76e-06284211319238
Pubmed

Bidirectional control of postsynaptic density-95 (PSD-95) clustering by Huntingtin.

DLG4 HTT

5.76e-06284224347167
Pubmed

Expression of sucrase-isomaltase and dipeptidylpeptidase IV in human small intestine and colon.

DPP4 SI

5.76e-0628421677636
Pubmed

Role of a propeller loop in the quaternary structure and enzymatic activity of prolyl dipeptidases DPP-IV and DPP9.

DPP4 DPP9

5.76e-06284222001206
Pubmed

MEL4B3, a novel mRNA is induced in skin tumors and regulated by TGF-beta and pro-inflammatory cytokines.

TGFB1 FNDC1

5.76e-06284216098131
Pubmed

Calcium and osteoprotegerin regulate IGF1R expression to inhibit vascular calcification.

IGF1R TNFRSF11B

5.76e-06284221447702
Pubmed

Interaction of postsynaptic density protein-95 with NMDA receptors influences excitotoxicity in the yeast artificial chromosome mouse model of Huntington's disease.

DLG4 HTT

5.76e-06284219726651
Pubmed

Isoforms of dipeptidyl aminopeptidase IV from Pseudomonas sp. WO24: role of the signal sequence and overexpression in Escherichia coli.

DPP4 DPP9

1.73e-05384215866709
Pubmed

Low bone mineral density in patients with type 1 diabetes: association with reduced expression of IGF1, IGF1R and TGF B 1 in peripheral blood mononuclear cells.

TGFB1 IGF1R

1.73e-05384226663878
Pubmed

The effect of CD26-deficiency on dipeptidyl peptidase 8 and 9 expression profiles in a mouse model of Crohn's disease.

DPP4 DPP9

1.73e-05384229693275
Pubmed

Clustering and enhanced activity of an inwardly rectifying potassium channel, Kir4.1, by an anchoring protein, PSD-95/SAP90.

DLG1 DLG4

1.73e-0538429148889
Pubmed

GAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila discs large tumor suppressor in T lymphocytes.

DLG1 DLG4

1.73e-05384210859302
Pubmed

A specific N-terminal residue in Kv1.5 is required for upregulation of the channel by SAP97.

DLG1 DLG4

1.73e-05384216466689
Pubmed

Altered DNA methylation profile in idiopathic pulmonary fibrosis.

DDAH1 CLDN5

1.73e-05384222700861
Pubmed

TGF-β-induced expression of IGFBP-3 regulates IGF1R signaling in human osteosarcoma cells.

TGFB1 IGF1R

1.73e-05384223831640
Pubmed

Core2 O-glycan structure is essential for the cell surface expression of sucrase isomaltase and dipeptidyl peptidase-IV during intestinal cell differentiation.

DPP4 SI

1.73e-05384220841351
Pubmed

Extraenzymatic functions of the dipeptidyl peptidase IV-related proteins DP8 and DP9 in cell adhesion, migration and apoptosis.

DPP4 DPP9

1.73e-05384216704418
Pubmed

Tyrosine phosphorylation of VE-cadherin and claudin-5 is associated with TGF-β1-induced permeability of centrally derived vascular endothelium.

TGFB1 CLDN5

1.73e-05384221168935
Pubmed

Osteoprotegerin Expression in Liver is Induced by IL13 through TGFβ.

TGFB1 TNFRSF11B

1.73e-05384235060690
Pubmed

IGF1R-α6 integrin-S100A4 network governs the organ-specific metastasis of chemoresistant epithelial ovarian cancer cells.

IGF1R ITGA6

1.73e-05384234600083
Pubmed

The cytoplasmic domain of NrCAM binds to PDZ domains of synapse-associated proteins SAP90/PSD95 and SAP97.

DLG1 DLG4

1.73e-05384216882004
Pubmed

Targeting of PKA to glutamate receptors through a MAGUK-AKAP complex.

DLG1 DLG4

1.73e-05384210939335
Pubmed

DLC-1 tumor suppressor regulates CD105 expression on human non-small cell lung carcinoma cells through inhibiting TGF-β1 signaling.

TGFB1 DLC1

1.73e-05384231770531
Pubmed

Expression of MAGE-A1, -A9, -A11 in laryngeal squamous cell carcinoma and their prognostic significance: a retrospective clinical study.

MAGEA1 MAGEA11

1.73e-05384226766421
Pubmed

TGFβ1 exacerbates blood-brain barrier permeability in a mouse model of hepatic encephalopathy via upregulation of MMP9 and downregulation of claudin-5.

TGFB1 CLDN5

1.73e-05384226006017
Pubmed

von Willebrand factor and transforming growth factor-beta modulate immune response against coagulation factor VIII in FVIII-deficient mice.

TGFB1 F8

1.73e-05384217376515
Pubmed

Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis.

DPP4 DPP9

1.73e-05384223608773
Pubmed

SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein.

SNX27 SORL1

1.73e-05384227466343
Pubmed

Differential interaction of the tSXV motifs of the NR1 and NR2A NMDA receptor subunits with PSD-95 and SAP97.

DLG1 DLG4

1.73e-05384210336672
Pubmed

Intramolecular interactions regulate SAP97 binding to GKAP.

DLG1 DLG4

1.73e-05384211060025
Pubmed

BEGAIN (brain-enriched guanylate kinase-associated protein), a novel neuronal PSD-95/SAP90-binding protein.

DLG1 DLG4

1.73e-0538429756850
Pubmed

Osteoprotegerin promotes vascular fibrosis via a TGF-β1 autocrine loop.

TGFB1 TNFRSF11B

1.73e-05384221679949
Pubmed

Heat Shock Factor 1 Directly Regulates Postsynaptic Scaffolding PSD-95 in Aging and Huntington's Disease and Influences Striatal Synaptic Density.

DLG4 HTT

1.73e-05384234884918
Pubmed

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.

LPCAT1 CDC42BPA SYTL4 ITGA6 LRP6 ATG9A PLXNA1 CYB5R1

1.78e-0546784830194290
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

KARS1 MAN2B1 SNX27 CHD4 HSPA4 HTT EEF1A1

2.05e-0534484730333137
Pubmed

Molecular mechanisms regulating the differential association of kainate receptor subunits with SAP90/PSD-95 and SAP97.

DLG1 DLG4

3.45e-05484211279111
Pubmed

Expression of dipeptidyl peptidase-IV activity and/or structure homologs in human meningiomas.

DPP4 DPP9

3.45e-05484220043068
Pubmed

Whole exome sequencing identifies mutations in 10% of patients with familial non-syndromic cleft lip and/or palate in genes mutated in well-known syndromes.

LRP6 GRHL3

3.45e-05484229500247
Pubmed

Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling.

WNT3 LRP6

3.45e-05484218606139
Pubmed

Lano, a novel LAP protein directly connected to MAGUK proteins in epithelial cells.

DLG1 DLG4

3.45e-05484211440998
Pubmed

Early mouse development: lessons from gene targeting.

TGFB1 HTT

3.45e-0548428791525
Pubmed

Cypin: a cytosolic regulator of PSD-95 postsynaptic targeting.

DLG1 DLG4

3.45e-05484210595517
Pubmed

Downregulation of Rap1GAP Expression Activates the TGF-β/Smad3 Pathway to Inhibit the Expression of Sodium/Iodine Transporter in Papillary Thyroid Carcinoma Cells.

TGFB1 RAP1GAP

3.45e-05484234840979
Pubmed

A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis.

DLG1 DLG4

3.45e-05484215657400
Pubmed

Class III PI-3-kinase activates phospholipase D in an amino acid-sensing mTORC1 pathway.

PIK3C3 PLD1

3.45e-05484222024166
Pubmed

Alpha 6 integrins participate in pro-T cell homing to the thymus.

ITGA6 F8

3.45e-0548427621877
Pubmed

Lack of association between FXIII-Val34Leu, FVII-323 del/ins, and transforming growth factor beta1 (915G/T) gene polymorphisms and bronchopulmonary dysplasia: a single-center study.

TGFB1 F8

3.45e-05484219778283
Pubmed

Postsynaptic targeting of alternative postsynaptic density-95 isoforms by distinct mechanisms.

DLG1 DLG4

3.45e-05484212151521
Pubmed

Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein.

DLG1 DLG4

3.45e-0548429326658
Pubmed

Clustering of Genetic Anomalies of Cilia Outer Dynein Arm and Central Apparatus in Patients with Transposition of the Great Arteries.

HYDIN DNAH11

3.45e-05484236140829
Pubmed

Polyglutamine expansion of huntingtin impairs its nuclear export.

HSPA4 HTT

3.45e-05484215654337
Pubmed

LRP6 enhances glucose metabolism by promoting TCF7L2-dependent insulin receptor expression and IGF receptor stabilization in humans.

IGF1R LRP6

3.45e-05484223395167
Pubmed

Conditional mutagenesis in mice with heat shock promoter-driven cre transgenes.

IGF1R HTT

3.45e-05484210723724
Pubmed

Ggamma13 interacts with PDZ domain-containing proteins.

DLG1 DLG4

3.45e-05484216473877
Pubmed

Transforming growth factor-β, insulin-like growth factor I/insulin-like growth factor I receptor and vascular endothelial growth factor-A: prognostic and predictive markers in triple-negative and non-triple-negative breast cancer.

TGFB1 IGF1R

3.45e-05484225824321
Pubmed

Muscarinic-induced recruitment of plasma membrane Ca2+-ATPase involves PSD-95/Dlg/Zo-1-mediated interactions.

DLG1 DLG4

3.45e-05484219017653
Pubmed

GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering molecules.

DLG1 DLG4

3.45e-0548429024696
Pubmed

Expression pattern of membrane-associated guanylate kinases in interneurons of the visual cortex.

DLG1 DLG4

3.45e-05484221031555
Pubmed

Synaptic scaffold evolution generated components of vertebrate cognitive complexity.

DLG1 DLG4

3.45e-05484223201973
Pubmed

Association of the kinesin superfamily motor protein KIF1Balpha with postsynaptic density-95 (PSD-95), synapse-associated protein-97, and synaptic scaffolding molecule PSD-95/discs large/zona occludens-1 proteins.

DLG1 DLG4

3.45e-05484212097473
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ZNF106 RAP1GAP IGF1R DLC1 CDC42BPA PIK3C3 TEX2 PPP1R3E INPPL1 EEF1A1

4.34e-05861841036931259
Pubmed

Sema4c, a transmembrane semaphorin, interacts with a post-synaptic density protein, PSD-95.

DLG1 DLG4

5.74e-05584211134026
Pubmed

High prevalence of respiratory ciliary dysfunction in congenital heart disease patients with heterotaxy.

CCDC39 DNAH11

5.74e-05584222499950
Pubmed

Selective interaction of megalin with postsynaptic density-95 (PSD-95)-like membrane-associated guanylate kinase (MAGUK) proteins.

DLG1 DLG4

5.74e-05584212713445
Pubmed

alpha4beta1- and alpha6beta1-integrins are functional receptors for midkine, a heparin-binding growth factor.

ITGA6 LRP6

5.74e-05584215466886
Pubmed

SAP97 increases Kv1.5 currents through an indirect N-terminal mechanism.

DLG1 DLG4

5.74e-05584212860415
Pubmed

SAP90 binds and clusters kainate receptors causing incomplete desensitization.

DLG1 DLG4

5.74e-0558429808460
Pubmed

A global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transport.

ATP7A SNX27

5.74e-05584223563491
Pubmed

VPS34 K29/K48 branched ubiquitination governed by UBE3C and TRABID regulates autophagy, proteostasis and liver metabolism.

PIK3C3 UBE3C

5.74e-05584233637724
Pubmed

Localization of postsynaptic density-93 to dendritic microtubules and interaction with microtubule-associated protein 1A.

DLG1 DLG4

5.74e-0558429786987
Pubmed

Glutamatergic neurons induce expression of functional glutamatergic synapses in primary myotubes.

DLG1 DLG4

5.74e-05584222347480
Pubmed

Expression and prognostic assessment of dipeptidyl peptidase IV and related enzymes in B-cell chronic lymphocytic leukemia.

DPP4 DPP9

5.74e-05584220534982
Pubmed

Regulation of dipeptidyl peptidase 8 and 9 expression in activated lymphocytes and injured liver.

DPP4 DPP9

5.74e-05584223704821
Pubmed

High frequency of loss of allelic integrity at Wilms' tumor suppressor gene-1 locus in advanced breast tumors associated with aggressiveness of the tumor.

TGFB1 IGF1R

5.74e-05584219749460
Pubmed

Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases.

DLG1 DLG4

5.74e-0558428601796
Pubmed

Pancreatic islet and progenitor cell surface markers with cell sorting potential.

DPP4 DNER CLDN5 EPHA7

5.78e-058684421947380
Pubmed

Primary Ciliary Dyskinesia

HYDIN CCDC39 DNAH11

6.41e-053284320301301
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

NPHP1 IGF1R ATP7A SYTL4 INPPL1 ITGA6 DLG1

7.36e-0542184736976175
Pubmed

Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation.

SNX27 DLG4 SHROOM2

7.70e-053484330726710
Pubmed

Guanylyl cyclase/PSD-95 interaction: targeting of the nitric oxide-sensitive alpha2beta1 guanylyl cyclase to synaptic membranes.

DLG1 DLG4

8.59e-05684211572861
Pubmed

Impaired TrkB-mediated ERK1/2 activation in huntington disease knock-in striatal cells involves reduced p52/p46 Shc expression.

SHC3 HTT

8.59e-05684220442398
Pubmed

Huntingtin regulates RE1-silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) nuclear trafficking indirectly through a complex with REST/NRSF-interacting LIM domain protein (RILP) and dynactin p150 Glued.

PRICKLE1 HTT

8.59e-05684218922795
Pubmed

Disruption of the NMDA receptor-PSD-95 interaction in hippocampal neurons with no obvious physiological short-term effect.

DLG1 DLG4

8.59e-05684214529713
Pubmed

Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis.

DLG1 DLG4

8.59e-05684219118189
Pubmed

Direct integrin binding to insulin-like growth factor-2 through the C-domain is required for insulin-like growth factor receptor type 1 (IGF1R) signaling.

IGF1R ITGA6

8.59e-05684228873464
Pubmed

Plasma membrane Ca2+-atpase isoforms 2b and 4b interact promiscuously and selectively with members of the membrane-associated guanylate kinase family of PDZ (PSD95/Dlg/ZO-1) domain-containing proteins.

DLG1 DLG4

8.59e-05684211274188
Pubmed

Ferric Chelate Reductase 1 Like Protein (FRRS1L) Associates with Dynein Vesicles and Regulates Glutamatergic Synaptic Transmission.

FRRS1L DLG4

8.59e-05684229276473
Pubmed

Huntingtin-interacting protein HIP14 is a palmitoyl transferase involved in palmitoylation and trafficking of multiple neuronal proteins.

DLG4 HTT

8.59e-05684215603740
Pubmed

Differential K+ channel clustering activity of PSD-95 and SAP97, two related membrane-associated putative guanylate kinases.

DLG1 DLG4

8.59e-0568428938729
Pubmed

Quantifying domain-ligand affinities and specificities by high-throughput holdup assay.

SNX27 DLG1 DLG4

9.16e-053684326053890
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

PRICKLE1 C2orf74 CCDC39 DNAH11

1.04e-0410084425807483
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

CDC42BPA PRICKLE1 SNX27 DLG1 DLG4

1.19e-0419784536604605
InteractionLYN interactions

DPP4 RHOH IGF1R ATP7A CDC42BPA INPPL1 DENND2C DLG1 DLG4 PLD1 PLXNA1 HTT EPHA7

6.38e-067208213int:LYN
InteractionLYZL1 interactions

TGFB1 IGF1R MAN2B1 LRP6 PLXNA1 SORL1

8.64e-06118826int:LYZL1
InteractionDUSP10 interactions

IGF1R DLG1 DLG4 HTT SORL1

1.04e-0571825int:DUSP10
InteractionSRC interactions

DPP4 KARS1 IGF1R INPPL1 BAAT DLG4 CHD4 ATG9A PLD1 SHROOM2 HSPA4 SHC3

1.49e-056648212int:SRC
InteractionARF6 interactions

DPP4 CDC42BPA SYTL4 ITGA6 SNX27 DLG1 DLG4 PLD1 PLXNA1 HTT EPHA7

2.39e-055848211int:ARF6
InteractionMAPK12 interactions

IGF1R ITGA6 SNX27 DLG1 DLG4

2.65e-0586825int:MAPK12
InteractionSLURP1 interactions

TGFB1 IGF1R MAN2B1 PLXNA1 EEF1A1 SORL1

2.69e-05144826int:SLURP1
InteractionLAMTOR1 interactions

RHOH IGF1R ATP7A CDC42BPA PIK3C3 SNX27 DLG1 ATG9A PLD1 HTT EEF1A1 EPHA7

3.39e-057228212int:LAMTOR1
InteractionPEAK1 interactions

RHOH IGF1R INPPL1 DLG4 ATG9A EPHA7

4.37e-05157826int:PEAK1
InteractionPIK3R1 interactions

TGFB1 DPP4 RHOH IGF1R INPPL1 IL20RA SHC3 HTT EPHA7

4.48e-05412829int:PIK3R1
InteractionWNT3A interactions

WNT3 LRP6 DLG1 DLG4

4.69e-0549824int:WNT3A
InteractionGUCY1A2 interactions

DLG1 DLG4 HSPA4

5.07e-0518823int:GUCY1A2
InteractionEEF1A1 interactions

TGFB1 NPHP1 MAGEA1 KARS1 IGF1R INPPL1 DLG4 CHD4 UBE3C PLXNA1 HTT EEF1A1

5.72e-057628212int:EEF1A1
InteractionKIF1B interactions

MAGEA1 PIK3C3 DLG1 DLG4 HTT EEF1A1

7.49e-05173826int:KIF1B
InteractionFCHO2 interactions

NPHP1 IGF1R PRICKLE1 ATG9A EPHA7

8.27e-05109825int:FCHO2
InteractionRHOA interactions

TGFB1 RHOH LPCAT1 ATP7A DLC1 CDC42BPA PIK3C3 TEX2 ITGA6 DLG1 ATG9A PLD1 PLXNA1 HTT EPHA7

8.76e-0511998215int:RHOA
InteractionACBD3 interactions

RHOH IGF1R WDR12 CHD4 ATG9A HSPA4 EPHA7

8.93e-05259827int:ACBD3
InteractionDIRAS3 interactions

TGFB1 ATP7A CDC42BPA PIK3C3 ITGA6 DLG1 EPHA7

9.60e-05262827int:DIRAS3
InteractionSLITRK5 interactions

RHOH SNX27 DLG4 ATG9A

9.77e-0559824int:SLITRK5
InteractionKCNA5 interactions

NPHP1 DLG1 DLG4 CYB5R1

1.04e-0460824int:KCNA5
InteractionRAB35 interactions

NPHP1 ATP7A CDC42BPA TEX2 ITGA6 DLG1 PLD1 PLXNA1 HTT EPHA7

1.09e-045738210int:RAB35
InteractionNRAS interactions

ATP7A CDC42BPA SYTL4 ITGA6 LRP6 DLG1 ATG9A PLXNA1 CYB5R1 EEF1A1 EPHA7

1.20e-046998211int:NRAS
InteractionCENPV interactions

DPP4 SNX27 CHD4 HTT EPHA7

1.35e-04121825int:CENPV
InteractionYWHAG interactions

ZNF106 RAP1GAP IGF1R DLC1 CDC42BPA PIK3C3 PPP1R3E DENND2C SNX27 DLG4 ATG9A SHROOM2 HSPA4 HTT EEF1A1

1.37e-0412488215int:YWHAG
InteractionANKRD10 interactions

DPP9 ATG9A SHC3

1.40e-0425823int:ANKRD10
InteractionKCNAB1 interactions

DLG1 DLG4 HTT

1.40e-0425823int:KCNAB1
InteractionTHRSP interactions

TGFB1 IGF1R INPPL1 CHD4

1.43e-0465824int:THRSP
InteractionRHOB interactions

LPCAT1 IGF1R ATP7A CDC42BPA INPPL1 DENND2C ITGA6 LRP6 DLG1 PLD1 PLXNA1 EPHA7

1.44e-048408212int:RHOB
InteractionEPHA2 interactions

TGFB1 NPHP1 RHOH IGF1R ATP7A SYTL4 INPPL1 ITGA6 DLG1 HSPA4 EPHA7

1.54e-047198211int:EPHA2
InteractionFRMPD3 interactions

DLG4 FRMPD3

1.62e-045822int:FRMPD3
InteractionCAV1 interactions

RHOH LPCAT1 IGF1R DLC1 CDC42BPA ITGA6 LRP6 DLG1 PLD1 CHRM5 EPHA7

1.64e-047248211int:CAV1
InteractionCNP interactions

DPP4 RHOH IGF1R SNX27 DLG4 HTT

1.80e-04203826int:CNP
InteractionFIBIN interactions

TGFB1 IGF1R MAN2B1 PLXNA1

2.01e-0471824int:FIBIN
InteractionELFN2 interactions

RHOH DPP9 DLG4

2.20e-0429823int:ELFN2
InteractionMRAP2 interactions

ISLR2 TEX2 SNX27 EPHA7

2.75e-0477824int:MRAP2
InteractionC11orf52 interactions

IGF1R ATP7A CDC42BPA ITGA6 DLG1 PLXNA1 EPHA7

2.75e-04311827int:C11orf52
InteractionDKK1 interactions

DPP4 WNT3 LRP6

2.96e-0432823int:DKK1
InteractionOPTN interactions

MAGEA1 DDX59 PIK3C3 WDR12 ATG9A CMYA5 HSPA4 HTT

3.19e-04422828int:OPTN
InteractionCACNG2 interactions

DLG1 DLG4 EPHA7

3.24e-0433823int:CACNG2
InteractionSTEAP3 interactions

DPP4 RHOH SNX27 ATG9A EPHA7

3.25e-04146825int:STEAP3
InteractionFER1L6 interactions

EEF1A1 EEF1A1P5

3.39e-047822int:FER1L6
InteractionNLGN4X interactions

SNX27 DLG4

3.39e-047822int:NLGN4X
InteractionPIK3R2 interactions

DPP4 RHOH IGF1R INPPL1 EEF1A1 EPHA7

3.52e-04230826int:PIK3R2
InteractionPI15 interactions

MAN2B1 LRP6 PLXNA1 SORL1

3.66e-0483824int:PI15
InteractionAP3M1 interactions

RHOH SNX27 ATG9A PLD1 HTT

3.68e-04150825int:AP3M1
InteractionUNC5B interactions

RHOH IGF1R ATG9A EPHA7

3.84e-0484824int:UNC5B
InteractionKCNA1 interactions

DLG1 DLG4 HTT

3.87e-0435823int:KCNA1
CytobandXq28

MAGEA1 WASH6P MAGEA11 F8

3.17e-04176844Xq28
CytobandEnsembl 112 genes in cytogenetic band chrXq28

MAGEA1 WASH6P MAGEA11 F8

6.50e-04213844chrXq28
Cytoband16q22.2

MARVELD3 HYDIN

7.46e-042284216q22.2
GeneFamilyPDZ domain containing

SNX27 DLG1 DLG4 FRMPD3 SHROOM2

1.26e-041525851220
GeneFamilyFibronectin type III domain containing

FNDC1 IGF1R CMYA5 EPHA7 SORL1

1.60e-04160585555
GeneFamilyCD molecules|DASH family

DPP4 DPP9

2.10e-0475821205
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

DENND2C DENND2D

2.89e-0325582504
GeneFamilyCalcium voltage-gated channel subunits|Membrane associated guanylate kinases

DLG1 DLG4

3.13e-0326582904
CoexpressionGSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_UP

IGF1R MGAT4A ITGA6 TSHZ1 LY9 PLXNA1 SORL1

2.92e-06195837M3319
CoexpressionKONDO_EZH2_TARGETS

PRSS35 PIERCE1 DNER ITGA6 LY9 CRISPLD1 SORL1

8.38e-06229837M5301
CoexpressionGSE28783_CTRL_ANTI_MIR_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_DN

TGFB1 RHOH IGF1R LY9 TNFRSF11B HTT

4.12e-05199836M8356
CoexpressionGSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_6H_IFNA_STIM_UP

DPP4 IGF1R WNT3 LRP6 CCDC39 SORL1

4.12e-05199836M7414
CoexpressionCHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN

DPP4 PRICKLE1 PIK3C3 IL20RA DLG1 MARVELD3 HYDIN JHY

4.51e-05407838M2214
ToppCellSevere-MAIT|World / Disease group and Cell class

PRSS35 DPP4 PRICKLE1 PLD1 LY9 EEF1A1 SORL1

7.38e-081908477a92e0d6a021be23125495927b8571e25c83204a
ToppCellSevere-MAIT|Severe / Disease group and Cell class

PRSS35 DPP4 PRICKLE1 PLD1 LY9 EEF1A1 SORL1

7.38e-081908471c063dc1b62d9f9912aaf8d0297555a6545f5550
ToppCellHealthy/Control-CD4+_T_naive|World / Disease group and Cell class

DPP4 RHOH IGF1R MGAT4A ITGA6 LRP6 EEF1A1

8.21e-081938476218e6cbe44d92bb98d42ef2f5e18ab7a683b100
ToppCellHealthy_donor-CD4+_T_naive|Healthy_donor / disease group, cell group and cell class (v2)

DPP4 RHOH IGF1R MGAT4A ITGA6 LRP6 EEF1A1

8.51e-08194847a8a0368a4e0eb5654fdffc8a779b08ad402aa2eb
ToppCellCOVID_vent-Lymphocytic-T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

DPP4 RHOH MGAT4A ITGA6 LY9 EEF1A1 SORL1

9.44e-08197847ad702e440a74d54cfdcb8bb1c66bd8e0e71ab04e
ToppCell10x5'v1-week_12-13-Hematopoietic-MK-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TGFB1 PRICKLE1 SYTL4 DENND2C ITGA6 CLDN5

1.30e-061838466cbc88c27dc957d182526e84824f70c8e860bf74
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DPP4 IGF1R MGAT4A ITGA6 EEF1A1 SORL1

1.30e-06183846f2ef110bf29b1a8276ef216238363e542db262c1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MARVELD3 DNAI7 HYDIN TNFRSF11B EPHA7 DNAH11

1.43e-061868465c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DPP4 IGF1R MGAT4A ITGA6 EEF1A1 SORL1

1.43e-06186846c793a3d5709ad504c12fc3b2337746d90236d3ca
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIERCE1 DNAI7 HYDIN CCDC39 JHY DNAH11

1.48e-0618784604dba2ed09ee4180830bdf0191921696697ea234
ToppCellfacs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIERCE1 DNAI7 HYDIN CCDC39 JHY DNAH11

1.48e-06187846805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCelltumor_Lung-Epithelial_cells-tS3|tumor_Lung / Location, Cell class and cell subclass

NPHP1 PIERCE1 DNER DNAI7 HYDIN CCDC39

1.52e-0618884626326b4e298e33f9ba393fc632238aa8c54b1ea3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS15 MARVELD3 HYDIN TNFRSF11B EPHA7 DNAH11

1.57e-06189846904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellMulticiliated|World / shred by cell class for nasal brushing

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.57e-0618984634b110aef839376228c5a403a6b5047a945f472b
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.62e-061908469ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.62e-06190846833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.72e-06192846be592e661367affced9ebe80849b466e6adb3a34
ToppCellFetal_29-31_weeks-Immune-T_lymphocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RHOH MGAT4A ITGA6 DENND2D LY9 SORL1

1.72e-0619284669a2b04f03a1b82d067018379f7b8a116e954040
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DPP4 RHOH IGF1R MGAT4A ITGA6 EEF1A1

1.72e-0619284678546a6e077076834fd717607610ab6df3b6e7ba
ToppCellmoderate-Lymphoid-Treg|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TGFB1 DPP4 RHOH MGAT4A DENND2D LY9

1.72e-06192846e370ff5aaff7b7042ba9aaf93de43aa563b8b9f9
ToppCellmulticiliated|World / shred by cell class for turbinate

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.72e-061928460f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.72e-061928461b6cac8156e608061e1405e36e18d185b6fa8f6f
ToppCellASK452-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.77e-06193846c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCellBronchial_Brush|World / Tissue, Lineage and Cell class of Lung Cells from 10X

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.77e-061938463e693ac4c92576e3f2c9efdd3f1d96d3d336e260
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.77e-06193846e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellHealthy/Control-CD4+_T_naive|Healthy/Control / Disease group and Cell class

DPP4 IGF1R MGAT4A ITGA6 LRP6 EEF1A1

1.77e-06193846f5face746df3517c86d72e31ba8f1b78c4c6b481
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.77e-061938460b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellASK440-Epithelial-Ciliated|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.77e-06193846a0baa8be6f590b2031fede22be588715ae458e93
ToppCell10x3'2.3-week_12-13-Hematopoietic-MK-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TGFB1 PRICKLE1 SYTL4 DENND2C ITGA6 CLDN5

1.77e-061938463d4411b3c1cb160dec5db29f0c126d8827dfe185
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.83e-061948463cd90d01ed5a5ce65aad8284dab2537ec16e3d7c
ToppCellASK440-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.83e-06194846c84a7fa94fb06e08aae04db56c8c313b0afde1d7
ToppCell10x5'v1-week_12-13-Hematopoietic-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TGFB1 DLC1 PRICKLE1 SYTL4 DENND2C ITGA6

1.83e-06194846245a3eb6db9c862b73ad34a8cd2898a3688c16f6
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.83e-06194846b4ce60c06568123008b1081d644733cb91c28f51
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.83e-061948467a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCellASK452-Epithelial-Ciliated|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.83e-061948465aeb44657ab6f61b1abf98af28d3397d8e44c1aa
ToppCell10x3'2.3-week_14-16-Hematopoietic-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TGFB1 DLC1 PRICKLE1 SYTL4 DENND2C ITGA6

1.83e-06194846216cba1a04b1a24b080322bc950e7fa2dade5ff1
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.83e-06194846a46238514bca920c3e3713d23c18ba24a09e2a29
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DPP4 RHOH IGF1R MGAT4A ITGA6 EEF1A1

1.88e-06195846497d4bfbc38bcafab37e8a9c20bc9141f2e78d2a
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.88e-06195846649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DPP4 RHOH ITGA6 CLDN5 DENND2D EEF1A1

1.88e-0619584607035a5972a78b98e4ab2167e3a5000f9f3b0826
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.88e-06195846d211a836cf711fdb91b10d512f09d462be937cc5
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.88e-061958460e763f36786515698b593e5c93f6a56619c1242d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.88e-06195846581b04220587e1d5198b1abd6965965ace7803e7
ToppCell10x3'2.3-week_12-13-Hematopoietic-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TGFB1 DLC1 PRICKLE1 SYTL4 DENND2C ITGA6

1.88e-061958461e794839a251fbc6e6ce419b4c457ead35a04735
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.88e-0619584693b1559382a12cfb158aa5fac7386e38b4f87989
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.88e-06195846db4270c135c392ed443670981656e3cd5b95939d
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.88e-0619584634e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.88e-06195846129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.88e-061958463e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.88e-061958466365e3893e38231090ec2dbef010dec71dea3d07
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.88e-061958469651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.88e-0619584607a6bcef6af93ed87df455dee624037cb75e011a
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-T_lymphocytic-CD4-positive,_alpha-beta_T_cell|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DPP4 RHOH DENND2D LY9 EEF1A1 EEF1A1P5

1.94e-061968466bf68f7b7c5f40b4bccb40deff10b4194d114ece
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated-diff|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.94e-061968469a91a6e5f93ce3bb5a0fc63677553f4c2df95c43
ToppCellNS-critical-d_07-13-Epithelial-Ciliated-diff|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 EEF1A1

2.00e-0619784632484fb5dde0a4525dd8028dde01ca5a4e51e4b6
ToppCellCOVID-19_Severe-Lymphoid_T/NK-CD4+_T_naive|COVID-19_Severe / Disease group, lineage and cell class

DPP4 RHOH IGF1R MGAT4A ITGA6 EEF1A1

2.00e-0619784607f74bdadfd28e1d55b3f4a3bf87d5dd65a2e9c5
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

2.00e-061978466865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

2.00e-0619784691637bdeab85024b5a02d1066f76cb803a2d6420
ToppCellNS-critical-d_0-4-Epithelial-Ciliated-diff|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

2.00e-0619784662e20ef825b92908d7732aa625dcff7b95ef6ca8
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

2.00e-0619784622c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DPP4 RHOH IGF1R MGAT4A ITGA6 EEF1A1

2.00e-061978469f0d91bb7aec4f2442259eca1ddf7905f8d40e9b
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

2.00e-061978463bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

2.00e-06197846e453d085182364ca347cbcc9dc995c62c3353016
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

2.00e-0619784687db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DPP4 RHOH IGF1R MGAT4A ITGA6 EEF1A1

2.00e-06197846258dfe69b5faeaee709422f873b144ca5e4a6452
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

2.00e-06197846d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DPP4 RHOH IGF1R MGAT4A ITGA6 EEF1A1

2.00e-06197846bf80e39cd68fd5bb85c8726d4f82648391de74ad
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DPP4 RHOH IGF1R MGAT4A ITGA6 EEF1A1

2.00e-06197846296b27348ca7e9acf746f752cf810e4e5baea76c
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-CD8+_T_naive|Int-URO / Disease, condition lineage and cell class

DPP4 RHOH PPP1R3E DENND2C ITGA6 DENND2D

2.06e-061988468c7d00d8c27fb47954d8ac53eebc4582e92b970c
ToppCelldistal-Epithelial-Ciliated-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PIERCE1 DNER DNAI7 HYDIN CCDC39 DNAH11

2.12e-061998462de1fe124737a6cca4b3805ab3056f9d9d7c16c7
ToppCelldistal-1-Epithelial-Ciliated|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PIERCE1 DNER DNAI7 HYDIN CCDC39 DNAH11

2.12e-061998464120e4a2bc05adebe1e1e9670ed7ea55142eb83d
ToppCellBiopsy_Control_(H.)-Epithelial-Ciliated|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

2.18e-062008469ae434c78e08adf95da49c85616e3ca72d1227bf
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD4+_T_naive|COVID-19_Severe / Disease, condition lineage and cell class

DPP4 RHOH IGF1R MGAT4A ITGA6 EEF1A1

2.18e-062008461fb96090b5205e95ec21378bf4b88eec7257cf7e
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Mesenchymal-Cilia-bearing_cell|3m / Sample Type, Dataset, Time_group, and Cell type.

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39 JHY

2.18e-062008460d14a950172a56b11fdebee8f4e13b0c10e0d592
ToppCellmild-CD4+_T_naive|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DPP4 RHOH IGF1R MGAT4A ITGA6 EEF1A1

2.18e-06200846f63fa394093e93a2e3d186dd37bcfa9d2901218e
ToppCellInt-URO-Lymphocyte-T_NK-CD8_Naive|Int-URO / Disease, Lineage and Cell Type

DPP4 PPP1R3E DENND2C ITGA6 DENND2D

1.03e-0515284552d6f9cf1f4637c922f582705d625b4cbe3dc0c2
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PRSS35 ISLR2 DDAH1 DLC1 CMYA5

1.40e-0516284558da6bc04cdac0002b0e6a751c96ff95e1a7f70f
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PRSS35 ISLR2 DDAH1 DLC1 CMYA5

1.40e-051628454d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCellCiliated_cells-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

1.48e-05164845fd30c55d0d75ef8b9396435d836187168095152b
ToppCellsystemic_lupus_erythematosus-treated-Hematopoietic-Progen-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RHOH ITGA6 CLDN5 DENND2D EEF1A1

1.81e-0517184561d622153b91702ef21b0efc7b9581e592b7ccea
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10|TCGA-Brain / Sample_Type by Project: Shred V9

TEX2 IL20RA DNAI7 CMYA5 JHY

1.81e-0517184574be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCellsystemic_lupus_erythematosus-treated-Hematopoietic-Progen|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

RHOH ITGA6 CLDN5 DENND2D EEF1A1

1.81e-0517184509b3fa120f63c411f8a0dd6bd230a9720ce83fb1
ToppCellCiliated_cells-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

NPHP1 PIERCE1 DNAI7 HYDIN CCDC39

1.86e-05172845187ae91148d293537afc77e10da2b64302322224
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TGFB1 DPP4 RHOH DENND2D SORL1

2.14e-05177845f1efd9c3074d5635700fe7fbebf3dd0b1e0a84f1
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_naive-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DPP4 RHOH MGAT4A ITGA6 EEF1A1

2.14e-05177845db6de487ef7976b444afadbf3ac60b3259925566
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS15 HYDIN TNFRSF11B EPHA7 DNAH11

2.20e-05178845c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCellLPS-antiTNF-Lymphocytic_NKT|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TGFB1 DPP4 RHOH DENND2D SORL1

2.26e-05179845ecea75c568911ff56939c9f67ab901497bd4356c
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPHP1 PIERCE1 DNAI7 HYDIN DNAH11

2.32e-051808451f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS15 HYDIN TNFRSF11B EPHA7 DNAH11

2.38e-051818456a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCellLPS_only-Lymphocytic_NKT-T_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TGFB1 DPP4 RHOH ITGA6 SORL1

2.38e-05181845a4347ae554e6dcf03c7001a2b69332b377c7c034
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS15 HYDIN TNFRSF11B JHY EPHA7

2.38e-051818456956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS15 HYDIN TNFRSF11B EPHA7 DNAH11

2.44e-051828455e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell21-Trachea-Epithelial-Multiciliated_precursor|Trachea / Age, Tissue, Lineage and Cell class

NPHP1 DDAH1 PIERCE1 DNAI7 JHY

2.44e-051828456e35892fa959ee31591850ded8f1088195ddeb01
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

2.44e-05182845e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCellfacs-Skin-Telogen-3m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT3 ITGA6 IL20RA GRHL3 HSPA4

2.51e-0518384526b18d1cc5d98f185176e100bafb9bc9081c66f7
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)-|367C / Donor, Lineage, Cell class and subclass (all cells)

PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

2.51e-05183845b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS15 HYDIN TNFRSF11B EPHA7 DNAH11

2.51e-05183845cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)|367C / Donor, Lineage, Cell class and subclass (all cells)

PIERCE1 DNAI7 HYDIN CCDC39 DNAH11

2.51e-05183845cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS15 HYDIN TNFRSF11B EPHA7 DNAH11

2.57e-05184845da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIERCE1 DNAI7 HYDIN CCDC39 JHY

2.57e-05184845797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
Diseasedevelopmental and epileptic encephalopathy 33 (implicated_via_orthology)

EEF1A1 EEF1A1P5

2.07e-053782DOID:0080463 (implicated_via_orthology)
DiseaseParkinson's disease (biomarker_via_orthology)

DLG1 DLG4 HSPA4

6.85e-0530783DOID:14330 (biomarker_via_orthology)
DiseasePrimary ciliary dyskinesia

HYDIN CCDC39 DNAH11

1.19e-0436783cv:C0008780
Diseasevisceral heterotaxy (implicated_via_orthology)

C2orf74 CCDC39 DNAH11

1.29e-0437783DOID:0050545 (implicated_via_orthology)
Diseasebenign neoplasm (implicated_via_orthology)

DLG1 DLG4

1.91e-048782DOID:0060072 (implicated_via_orthology)
Diseaseage at onset, coronary stenosis

DLC1 PLD1

2.45e-049782EFO_0004847, MONDO_0006715
DiseasePrimary Ciliary Dyskinesia

HYDIN CCDC39 DNAH11

2.65e-0447783C4551720
Diseasefactor VIII deficiency (is_implicated_in)

TGFB1 F8

3.74e-0411782DOID:12134 (is_implicated_in)
Diseasetype 2 diabetes mellitus (is_marker_for)

TGFB1 HSPA4 F8 TNFRSF11B

4.73e-04136784DOID:9352 (is_marker_for)
DiseaseKartagener syndrome (implicated_via_orthology)

CCDC39 DNAH11

6.15e-0414782DOID:0050144 (implicated_via_orthology)
DiseaseUremia

TGFB1 TNFRSF11B

9.14e-0417782C0041948
Diseaseepilepsy (implicated_via_orthology)

PRICKLE1 ITGA6 EEF1A1 EEF1A1P5

9.32e-04163784DOID:1826 (implicated_via_orthology)
DiseaseMood Disorders

TGFB1 DLG4 HSPA4 HTT

1.04e-03168784C0525045
Diseasebipolar disorder (is_marker_for)

RAP1GAP TNFRSF11B

1.15e-0319782DOID:3312 (is_marker_for)
Diseasecarotid artery disease (is_marker_for)

TGFB1 TNFRSF11B

1.15e-0319782DOID:3407 (is_marker_for)
Diseasehydrocephalus (implicated_via_orthology)

HYDIN CCDC39

1.15e-0319782DOID:10908 (implicated_via_orthology)
DiseaseLung diseases

TGFB1 IGF1R DNAH11

1.17e-0378783C0024115
Diseasedilated cardiomyopathy (implicated_via_orthology)

DNER EEF1A1 EEF1A1P5

1.26e-0380783DOID:12930 (implicated_via_orthology)
Diseasehaptoglobin measurement

DLC1 HYDIN

1.40e-0321782EFO_0004640
DiseaseHepatitis, Chronic

TGFB1 ATP7A

1.54e-0322782C0019189
DiseaseChronic active hepatitis

TGFB1 ATP7A

1.54e-0322782C0520463
DiseaseChronic Persistent Hepatitis

TGFB1 ATP7A

1.54e-0322782C0149519
DiseaseBronchiectasis

CCDC39 DNAH11

1.54e-0322782C0006267
DiseaseCryptogenic Chronic Hepatitis

TGFB1 ATP7A

1.54e-0322782C0524611
Diseasecolon adenocarcinoma (is_implicated_in)

TGFB1 CHD4

2.15e-0326782DOID:234 (is_implicated_in)
Diseasewhite matter integrity, age at assessment

WNT3 WDR12

2.15e-0326782EFO_0004641, EFO_0008007
DiseaseSchizophrenia

TGFB1 PIK3C3 DLG1 DLG4 CLDN5 CHD4 CMYA5 CHRM5

2.30e-03883788C0036341
Diseasepancreatic ductal adenocarcinoma (is_marker_for)

TGFB1 PLD1

2.32e-0327782DOID:3498 (is_marker_for)
Diseasepancreatic cancer (is_marker_for)

TGFB1 RAP1GAP MGAT4A

2.46e-03101783DOID:1793 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
YEDLPRKPEVTDLEY

BAAT

196

Q14032
EKYRYQDEDTPPQEH

DLG1

106

Q12959
QLSPGEDYYETENPK

C13orf42

296

A0A1B0GVH6
ENVPSDSPKEVYEVY

DNAH11

2391

Q96DT5
QTIDDYYTDASPSPR

ABHD3

316

Q8WU67
SYEEDKRTSVPYTRP

RAD54L2

971

Q9Y4B4
NTKSVPEYSEVAYPD

AGTPBP1

636

Q9UPW5
YSFYLPKEPREDKSS

ADAMTS15

796

Q8TE58
RKPTYESYELPARSQ

ATP7A

1411

Q04656
PPEGEEEKTQAYYVI

CCDC39

651

Q9UFE4
DPRASYLESEKSYPA

ISLR2

646

Q6UXK2
PESYYPDLTNLKETF

MGAT4A

211

Q9UM21
KATAPPERTSDYYRV

PIERCE1

16

Q5BN46
VYSPSEEEKRNPALY

LPCAT1

276

Q8NF37
EKYLEYRQVPDSDPA

MAGEA1

246

P43355
PTSYPSLYEDALREE

MAGEA11

411

P43364
RKEPFTLEAYYSSPQ

HSPA4

436

P34932
QQPIEDKYSDLRYDP

JHY

116

Q6NUN7
SEPESPLNASYVYKE

DDX59

156

Q5T1V6
EVSFYYSEENKLPEP

IGF1R

1276

P08069
TNPEVKYNYTEDPTI

PLXNA1

1036

Q9UIW2
KYNYTEDPTILRIDP

PLXNA1

1041

Q9UIW2
PTPRSQYLSAEENYE

LRP6

1571

O75581
YSDESLQYPKTVRVP

DPP4

241

P27487
PLVLAPDDRSYKSQY

F8

416

P00451
VSYTDPDQFVYKTRP

ITGA6

266

P23229
KTYIDPETYEDPNRA

EPHA7

606

Q15375
TIPPDKTVIEYEYDV

IL20RA

391

Q9UHF4
SPKDRLRLYTPDNYE

PRICKLE1

696

Q96MT3
KVPLDTTEYPEEQYV

HTT

736

P42858
RPTTAYIYITEENKP

HYDIN

3536

Q4G0P3
PEDYPSLKSDFEYTL

GRHL3

221

Q8TE85
PSPALEERKTDSYRY

DPP9

291

Q86TI2
DRYYPPREEETNEIE

CRISPLD1

246

Q9H336
EARAPKPYVSQISEY

FRMPD3

1646

Q5JV73
SPPASERVVSIYKYE

FRRS1L

246

Q9P0K9
YDEDYEFETSRPPTT

FNDC1

1561

Q4ZHG4
DSTEPPYSQKRYEEI

EEF1A1

156

P68104
TEYQRLEASYSDSPP

ATG9A

6

Q7Z3C6
RPTTPEATETYTLEY

CMYA5

3826

Q8N3K9
NEYPTPRSYTREHKE

C2orf74

171

A8MZ97
EGLQKYTYPPETTEE

DNAI7

411

Q6TDU7
YTYPPETTEEFETEN

DNAI7

416

Q6TDU7
EDIIYPTKENPYEDI

DENND2C

311

Q68D51
KYRYQDEDTPPLEHS

DLG4

11

P78352
STPRPGREEVEYYQS

MARVELD3

166

Q96A59
ADYDPVTPYVTEVES

LY9

581

Q9HBG7
DPRSPEYNAKELVDY

MAN2B1

281

O00754
DSTEPPYSQKRYEEI

EEF1A1P5

156

Q5VTE0
KNPEVSRPYVCTYED

KLF18

956

A0A0U1RQI7
VDPTVKYERQPEYLD

CHD4

706

Q14839
IAYEDYSPDDKPLVT

DNER

716

Q8NFT8
HRTPEEYPESAKVYE

DDAH1

236

O94760
TYPVEILYTKEPETD

DHX8

741

Q14562
RSEDDYEPIITYQFP

DENND2D

66

Q9H6A0
LVPRTYLEPYSEEEE

NPHP1

201

O15259
NPLYDETLRYEIPES

SYTL4

421

Q96C24
KTPTYREPVSDYQVL

TAF8

161

Q7Z7C8
DPYDKPNTIYIERHE

SORL1

256

Q92673
PEEESVDPNQYYKIR

KARS1

66

Q15046
DYDVSPSDPKIQEVY

PLD1

41

Q13393
SETFPEAYKPTVYEN

RHOH

26

Q15669
YYRSQRPSLEEEPEE

PPP1R3E

26

Q9H7J1
SYPPTKQLTYEEQDL

PIK3C3

301

Q8NEB9
LKTEEDYIPYPSVHE

RAP1GAP

21

P47736
PDTTDYVAYVAKDPV

SHC3

261

Q92529
SEEEISFPPTYRYER

INPPL1

651

O15357
PRDYRYSEESTPADL

SHROOM2

1016

Q13796
PTTPISTYEDRLYDV

SI

1051

P14410
RPYTPVTSDEDQGYV

CYB5R1

96

Q9UHQ9
RSVYVPKEAYDSTLP

CDC42BPA

1211

Q5VT25
KNRESYPEDTVFYIP

DLC1

796

Q96QB1
TEKSDYDTPNYLLSP

CHRM5

351

P08912
EFYDPSVPVSQKYEL

CLDN5

146

O00501
QETFPPKYLHYDEET

TNFRSF11B

21

O00300
YNETSSSREESPEPY

STYXL2

1026

Q5VZP5
PTPSLSELEDYLSYE

PRSS35

71

Q8N3Z0
EPEPEADYYAKEVTR

TGFB1

96

P01137
FKPPTERDLVYYENS

WNT3

266

P56703
DYTEKQAVPISVPRY

SNX27

156

Q96L92
VEIEYVEKYTAPQPE

WDR12

81

Q9GZL7
RASYNEPKPEVTYIS

TEX2

591

Q8IWB9
FSSAKYPAPERLQEY

WASH6P

71

Q9NQA3
EDRIPYQDRESYSQP

ZNF106

106

Q9H2Y7
EDSLEKFEPSTLYPY

TSHZ1

521

Q6ZSZ6
YPETKPEVREEYITA

UBE3C

561

Q15386