Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransporter activity

ATP5MC3 SLC12A6 GJD2 SLC17A3 SLC35D2 SLC10A4 SLC19A2 ATP10B TMC4 SLCO6A1 ABCA9 SLC35D1 SLC6A1 ATP6V0D1 PKD2L2 SLC22A16 SLC15A2 SV2B SLC15A4 SLC22A13 SLC10A5 SCN5A SCN8A SCN9A LRP2 TRPV4 ATP13A3 SLC45A1 RFT1 SLC33A1

2.08e-08128914930GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

ATP5MC3 SLC12A6 GJD2 SLC17A3 SLC35D2 SLC10A4 SLC19A2 TMC4 SLCO6A1 ABCA9 SLC35D1 SLC6A1 ATP6V0D1 PKD2L2 SLC22A16 SLC15A2 SV2B SLC15A4 SLC22A13 SLC10A5 SCN5A SCN8A SCN9A TRPV4 ATP13A3 SLC45A1 SLC33A1

1.69e-07118014927GO:0022857
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC12A6 SLC17A3 SLC10A4 SLC6A1 SLC15A2 SLC15A4 SLC10A5 SLC45A1

3.10e-061191498GO:0015294
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC17A3 SLC35D2 SLC10A4 SLC19A2 SLCO6A1 SLC35D1 SLC6A1 SLC15A4 SLC22A13 SLC10A5 SLC33A1

1.29e-0529314911GO:0008514
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC12A6 SLC17A3 SLC35D2 SLC10A4 SLCO6A1 ABCA9 SLC35D1 SLC6A1 ATP6V0D1 SLC15A2 SLC15A4 SLC10A5 ATP13A3 SLC45A1

1.40e-0547714914GO:0022804
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC12A6 SLC17A3 SLC35D2 SLC10A4 SLCO6A1 SLC35D1 SLC6A1 SLC15A2 SLC15A4 SLC10A5 SLC45A1

1.42e-0529614911GO:0015291
GeneOntologyMolecularFunctionsymporter activity

SLC12A6 SLC17A3 SLC10A4 SLC6A1 SLC15A2 SLC15A4 SLC10A5 SLC45A1

1.71e-051501498GO:0015293
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

ATP5MC3 SLC12A6 SLC17A3 SLC10A4 SLC6A1 ATP6V0D1 PKD2L2 SLC15A2 SLC15A4 SLC10A5 SCN5A SCN8A SCN9A TRPV4 ATP13A3 SLC45A1

3.78e-0566414916GO:0008324
GeneOntologyMolecularFunctionUDP-glucuronic acid transmembrane transporter activity

SLC35D2 SLC35D1

5.53e-0521492GO:0005461
GeneOntologyMolecularFunctionUDP-N-acetylgalactosamine transmembrane transporter activity

SLC35D2 SLC35D1

5.53e-0521492GO:0005463
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

ATP5MC3 SLC12A6 SLC17A3 SLC10A4 SLC6A1 ATP6V0D1 PKD2L2 SLC15A2 SLC15A4 SLC10A5 SCN5A SCN8A SCN9A TRPV4 SLC45A1

7.24e-0562714915GO:0022890
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC12A6 SLC17A3 SLC10A4 SLC6A1 ATP6V0D1 SLC15A2 SLC15A4 SLC10A5 ATP13A3 SLC45A1

9.01e-0530114910GO:0022853
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

ATP5MC3 SLC12A6 SLC17A3 SLC10A4 TMC4 SLC6A1 ATP6V0D1 PKD2L2 SLC15A2 SLC15A4 SLC10A5 SCN5A SCN8A SCN9A TRPV4 ATP13A3 SLC45A1

9.10e-0579314917GO:0015075
GeneOntologyMolecularFunctionprotein serine/threonine phosphatase activity

CPPED1 DUSP8 LRRIQ4 PPP5C DUSP16 PHLPP1

1.68e-041091496GO:0004722
GeneOntologyMolecularFunctionmonocarboxylate:sodium symporter activity

SLC10A4 SLC6A1 SLC10A5

1.73e-04151493GO:0140161
GeneOntologyMolecularFunctionamide transmembrane transporter activity

SLC19A2 SLC15A2 SLC15A4 SLC33A1

2.67e-04421494GO:0042887
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC17A3 SLC10A4 SLC6A1 SLC10A5 SCN5A SCN8A SCN9A

3.02e-041711497GO:0015081
GeneOntologyMolecularFunctionpeptide:proton symporter activity

SLC15A2 SLC15A4

3.29e-0441492GO:0015333
GeneOntologyMolecularFunctionsecondary active monocarboxylate transmembrane transporter activity

SLC10A4 SLC6A1 SLC10A5

3.61e-04191493GO:0015355
GeneOntologyMolecularFunctionmyosin phosphatase activity

CPPED1 DUSP8 PPP5C DUSP16 PHLPP1

4.39e-04851495GO:0017018
GeneOntologyMolecularFunctioncalcium ion binding

CRACR2A PCDHGB1 CDHR1 FAT3 ADGRV1 FAT2 PKD2L2 GUCA1A ANKEF1 RHBDL3 LRP2 NECAB3 SYT5 PLCG1 EFCAB7

4.93e-0474914915GO:0005509
GeneOntologyMolecularFunctionUDP-N-acetylglucosamine transmembrane transporter activity

SLC35D2 SLC35D1

5.45e-0451492GO:0005462
GeneOntologyMolecularFunctiondipeptide transmembrane transporter activity

SLC15A2 SLC15A4

5.45e-0451492GO:0071916
GeneOntologyMolecularFunctionphosphoprotein phosphatase activity

CPPED1 DUSP8 LRRIQ4 MDP1 PPP5C DUSP16 PHLPP1

5.52e-041891497GO:0004721
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

ATP5MC3 SLC12A6 SLC17A3 SLC10A4 SLC6A1 ATP6V0D1 PKD2L2 SLC15A2 SLC15A4 SLC10A5 SCN5A SCN8A SCN9A TRPV4 SLC45A1

5.57e-0475814915GO:0015318
GeneOntologyMolecularFunctionphosphoric ester hydrolase activity

CPPED1 PLCXD1 ACP5 DUSP8 LRRIQ4 MDP1 PPP5C DUSP16 PHLPP1 PLCG1

6.55e-0438614910GO:0042578
GeneOntologyMolecularFunctionbile acid:sodium symporter activity

SLC10A4 SLC10A5

8.13e-0461492GO:0008508
GeneOntologyMolecularFunctionsolute:proton symporter activity

SLC15A2 SLC15A4 SLC45A1

8.30e-04251493GO:0015295
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN5A SCN8A SCN9A

9.33e-04261493GO:0005248
GeneOntologyMolecularFunctioncarbohydrate derivative transmembrane transporter activity

SLC35D2 SLC35D1 SLC15A4 SLC33A1

9.85e-04591494GO:1901505
GeneOntologyMolecularFunctionphosphatase activity

CPPED1 ACP5 DUSP8 LRRIQ4 MDP1 PPP5C DUSP16 PHLPP1

1.43e-032871498GO:0016791
GeneOntologyMolecularFunctionurate transmembrane transporter activity

SLC17A3 SLC22A13

1.92e-0391492GO:0015143
GeneOntologyMolecularFunctionpeptide transmembrane transporter activity

SLC15A2 SLC15A4

1.92e-0391492GO:1904680
GeneOntologyMolecularFunctionsalt transmembrane transporter activity

SLC17A3 SLC22A13

1.92e-0391492GO:1901702
GeneOntologyMolecularFunctionacid phosphatase activity

ACP5 MDP1

1.92e-0391492GO:0003993
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC10A4 SLC6A1 SLC10A5

2.24e-03351493GO:0005343
GeneOntologyMolecularFunctionphosphorylation-dependent protein binding

TOPBP1 VAV1

2.39e-03101492GO:0140031
GeneOntologyMolecularFunctionMAP kinase tyrosine phosphatase activity

DUSP8 DUSP16

2.39e-03101492GO:0033550
GeneOntologyMolecularFunctionSUMO transferase activity

ZMIZ1 UHRF2 PML

2.43e-03361493GO:0019789
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC12A6 SLC17A3 SLC10A4 SLC6A1 PKD2L2 SLC10A5 SCN5A SCN8A SCN9A TRPV4

2.62e-0346514910GO:0046873
GeneOntologyMolecularFunctionpolyamine transmembrane transporter activity

SLC22A16 ATP13A3

2.91e-03111492GO:0015203
GeneOntologyMolecularFunctionpyrimidine nucleotide-sugar transmembrane transporter activity

SLC35D2 SLC35D1

2.91e-03111492GO:0015165
GeneOntologyMolecularFunctionprotein tyrosine/threonine phosphatase activity

DUSP8 DUSP16

2.91e-03111492GO:0008330
GeneOntologyMolecularFunctioninositol phosphate kinase activity

ITPKA IP6K2

2.91e-03111492GO:0180030
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC17A3 SLC10A4 SLC6A1 SLC10A5

3.17e-03811494GO:0015370
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC19A2 SLC22A16 SLC15A4 ATP13A3

3.47e-03831494GO:0015101
GeneOntologyMolecularFunctionG-protein alpha-subunit binding

ADGRV1 PPP5C GPSM2

4.04e-03431493GO:0001965
GeneOntologyMolecularFunctionMAP kinase tyrosine/serine/threonine phosphatase activity

DUSP8 DUSP16

4.09e-03131492GO:0017017
GeneOntologyBiologicalProcessmaintenance of animal organ identity

ADGRV1 PKP2 USH2A

3.73e-0651503GO:0048496
GeneOntologyBiologicalProcesscarbohydrate derivative transport

SLC17A3 SLC35D2 SLC35D1 SLC15A2 SLC15A4 RFT1 SLC33A1

6.49e-06961507GO:1901264
GeneOntologyBiologicalProcessmonoatomic ion transport

ATP5MC3 SLC12A6 CXCR3 CRACR2A SLC17A3 SLC10A4 TMC4 SLC6A1 ATP6V0D1 PKD2L2 SLC22A16 SLC15A2 MTOR SLC15A4 SLC10A5 GNB5 SCN5A SCN8A SCN9A LRP2 PKP2 TRPV4 ATP13A3 PLCG1 PML

1.90e-05137415025GO:0006811
GeneOntologyBiologicalProcessmonoatomic cation transport

ATP5MC3 SLC12A6 CXCR3 CRACR2A SLC17A3 SLC10A4 SLC6A1 ATP6V0D1 PKD2L2 SLC15A2 SLC15A4 SLC10A5 GNB5 SCN5A SCN8A SCN9A LRP2 PKP2 TRPV4 ATP13A3 PLCG1 PML

3.32e-05115715022GO:0006812
GeneOntologyBiologicalProcessUDP-N-acetylgalactosamine transmembrane transport

SLC35D2 SLC35D1

5.25e-0521502GO:0015789
GeneOntologyBiologicalProcessUDP-glucuronic acid transmembrane transport

SLC35D2 SLC35D1

5.25e-0521502GO:0015787
GeneOntologyBiologicalProcessneuronal action potential

GJD2 MTOR SCN5A SCN8A SCN9A

9.52e-05631505GO:0019228
GeneOntologyBiologicalProcesspeptidoglycan transport

SLC15A2 SLC15A4

1.57e-0431502GO:0015835
GeneOntologyBiologicalProcesstransmission of nerve impulse

GJD2 CNTNAP1 MTOR SCN5A SCN8A SCN9A

1.70e-041121506GO:0019226
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

ATP5MC3 SLC12A6 CXCR3 CRACR2A SLC17A3 TMC4 SLC6A1 ATP6V0D1 PKD2L2 SLC15A2 MTOR SLC15A4 GNB5 SCN5A SCN8A SCN9A TRPV4 ATP13A3 PLCG1 PML

1.72e-04111515020GO:0034220
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

ATP5MC3 SLC12A6 CXCR3 CRACR2A SLC17A3 SLC6A1 ATP6V0D1 PKD2L2 SLC15A2 SLC15A4 GNB5 SCN5A SCN8A SCN9A TRPV4 ATP13A3 PLCG1 PML

1.73e-0494215018GO:0098655
GeneOntologyCellularComponentpostsynaptic density membrane

ITGA8 LRRC4B LRRC4C SLITRK1 ELFN1 SCN8A ANP32E

1.36e-041571497GO:0098839
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN5A SCN8A SCN9A

2.24e-04171493GO:0001518
GeneOntologyCellularComponentUSH2 complex

ADGRV1 USH2A

3.00e-0441492GO:1990696
GeneOntologyCellularComponentpiP-body

TDRKH MAEL

4.98e-0451492GO:0071547
GeneOntologyCellularComponentpostsynaptic specialization membrane

ITGA8 LRRC4B LRRC4C SLITRK1 ELFN1 SCN8A ANP32E

6.08e-042011497GO:0099634
GeneOntologyCellularComponentstereocilia ankle link

ADGRV1 USH2A

7.43e-0461492GO:0002141
GeneOntologyCellularComponentstereocilia ankle link complex

ADGRV1 USH2A

7.43e-0461492GO:0002142
GeneOntologyCellularComponentstereocilium membrane

ADGRV1 USH2A

7.43e-0461492GO:0060171
GeneOntologyCellularComponentpericiliary membrane compartment

ADGRV1 USH2A

7.43e-0461492GO:1990075
GeneOntologyCellularComponentglutamatergic synapse

DLG5 CNTNAP1 ITGA8 LRRC4B LRRC4C SLITRK1 ITPKA SV2B MTOR ELFN1 SCN8A ANP32E ELAVL1 LPAR2 PLCG1

7.53e-0481714915GO:0098978
GeneOntologyCellularComponentapical part of cell

SLC12A6 MGAM SLC17A3 ITGA8 ATP6V0D1 FRMD6 SLC15A2 SLC22A13 LRP2 GPSM2 TRPV4 USH2A

1.12e-0359214912GO:0045177
GeneOntologyCellularComponentsodium channel complex

SCN5A SCN8A SCN9A

1.13e-03291493GO:0034706
GeneOntologyCellularComponentstereocilia coupling link

ADGRV1 USH2A

1.37e-0381492GO:0002139
DomainMFS_dom

SLC17A3 SLC19A2 SLCO6A1 SLC22A16 SLC15A2 SV2B SLC15A4 SLC22A13 SLC33A1

1.36e-061341509IPR020846
DomainTPR_REGION

P3H3 IFT172 TTC27 TTC6 WDR19 TMTC1 PPP5C GPSM2 ZC3H7B

7.54e-061651509PS50293
DomainTPR

P3H3 IFT172 TTC27 TTC6 WDR19 TMTC1 PPP5C GPSM2 ZC3H7B

7.54e-061651509PS50005
DomainNa_trans_cytopl

SCN5A SCN8A SCN9A

9.98e-0661503PF11933
DomainNa_trans_cytopl

SCN5A SCN8A SCN9A

9.98e-0661503IPR024583
DomainTPR-like_helical_dom

P3H3 IFT172 TTC27 TTC6 WDR19 TMTC1 PPP5C MTOR GPSM2 ZC3H7B

1.92e-0523315010IPR011990
DomainTPR-contain_dom

P3H3 TTC27 TTC6 WDR19 TMTC1 PPP5C GPSM2 ZC3H7B

2.88e-051501508IPR013026
DomainLRR

LRRC4B LRRIQ4 LRRC4C CPN2 SLITRK1 LRR1 ELFN1 PHLPP1 ANP32E

3.63e-052011509PS51450
DomainNa_channel_asu

SCN5A SCN8A SCN9A

5.85e-05101503IPR001696
DomainNa_trans_assoc

SCN5A SCN8A SCN9A

5.85e-05101503IPR010526
DomainNa_trans_assoc

SCN5A SCN8A SCN9A

5.85e-05101503PF06512
DomainCompl_C2_B

CFB C2

6.41e-0521502IPR011360
DomainLRR_TYP

LRRC4B LRRIQ4 LRRC4C CPN2 SLITRK1 LRR1 ELFN1 PHLPP1

9.31e-051771508SM00369
DomainLeu-rich_rpt_typical-subtyp

LRRC4B LRRIQ4 LRRC4C CPN2 SLITRK1 LRR1 ELFN1 PHLPP1

9.31e-051771508IPR003591
Domain-

FAT3 CNTNAP1 ADGRV1 FAT2 LRBA USH2A

1.17e-049515062.60.120.200
DomainPTR2_symporter_CS

SLC15A2 SLC15A4

1.91e-0431502IPR018456
DomainLAM_G_DOMAIN

FAT3 CNTNAP1 FAT2 USH2A

2.39e-04381504PS50025
Domain-

P3H3 TTC27 WDR19 TMTC1 PPP5C MTOR GPSM2 ZC3H7B

2.73e-0420715081.25.40.10
DomainLaminin_G_2

FAT3 CNTNAP1 FAT2 USH2A

2.92e-04401504PF02210
DomainLeu-rich_rpt

LRRC4B LRRIQ4 LRRC4C CPN2 SLITRK1 LRR1 ELFN1 PHLPP1 ANP32E

3.49e-042711509IPR001611
DomainPTR2_2

SLC15A2 SLC15A4

3.80e-0441502PS01023
DomainLRR_1

LRRC4B LRRIQ4 LRRC4C CPN2 SLITRK1 LRR1 PHLPP1 ANP32E

3.98e-042191508PF00560
DomainLamG

FAT3 CNTNAP1 FAT2 USH2A

4.23e-04441504SM00282
DomainLRR_8

LRRC4B LRRIQ4 LRRC4C CPN2 SLITRK1 ELFN1 PHLPP1

4.68e-041711507PF13855
DomainIQ

MYH11 LRRIQ4 SCN5A SCN8A SCN9A

4.90e-04811505SM00015
DomainEF-hand-dom_pair

CRACR2A GUCA1A ANKEF1 RHBDL3 SCN8A SCN9A NECAB3 PLCG1 EFCAB7

5.29e-042871509IPR011992
DomainTPR

TTC27 TTC6 TMTC1 PPP5C GPSM2 ZC3H7B

6.14e-041291506SM00028
DomainPOT_fam

SLC15A2 SLC15A4

6.31e-0451502IPR000109
DomainPTR2

SLC15A2 SLC15A4

6.31e-0451502PF00854
DomainTPR_1

TTC6 TMTC1 PPP5C GPSM2 ZC3H7B

7.94e-04901505IPR001440
DomainCys-rich_flank_reg_C

LRRC4B LRRC4C CPN2 SLITRK1 ELFN1

7.94e-04901505IPR000483
DomainTPR_1

TTC6 TMTC1 PPP5C GPSM2 ZC3H7B

7.94e-04901505PF00515
DomainLRRCT

LRRC4B LRRC4C CPN2 SLITRK1 ELFN1

7.94e-04901505SM00082
DomainIQ_motif_EF-hand-BS

MYH11 LRRIQ4 SCN5A SCN8A SCN9A

7.94e-04901505IPR000048
DomainIQ

MYH11 LRRIQ4 SCN5A SCN8A SCN9A

9.21e-04931505PS50096
DomainFAT

TMTC1 MTOR

9.41e-0461502PF02259
DomainPIK-rel_kinase_FAT

TMTC1 MTOR

9.41e-0461502IPR003151
Domain-

LRRC4B LRRIQ4 LRRC4C CPN2 SLITRK1 LRR1 ELFN1 PHLPP1 ANP32E

1.17e-0332115093.80.10.10
DomainLaminin_G

FAT3 CNTNAP1 FAT2 USH2A

1.21e-03581504IPR001791
DomainSBF

SLC10A4 SLC10A5

1.31e-0371502PF01758
DomainBilAc:Na_symport/Acr3

SLC10A4 SLC10A5

1.31e-0371502IPR002657
DomainIPK

ITPKA IP6K2

1.31e-0371502PF03770
DomainIPK

ITPKA IP6K2

1.31e-0371502IPR005522
DomainL_dom-like

LRRC4B LRRIQ4 LRRC4C CPN2 SLITRK1 LRR1 ELFN1 PHLPP1 ANP32E

1.36e-033281509IPR032675
DomainMetallophos

CPPED1 ACP5 PPP5C

1.44e-03281503PF00149
DomainCalcineurin-like_PHP_ApaH

CPPED1 ACP5 PPP5C

1.44e-03281503IPR004843
DomainARM-type_fold

IFT172 PSMD1 PPP6R1 ECPAS FMNL3 URB1 MTOR PKP2 LRBA

1.70e-033391509IPR016024
DomainMetallo-depent_PP-like

CPPED1 ACP5 PPP5C

1.76e-03301503IPR029052
Domain-

CPPED1 ACP5 PPP5C

1.76e-033015033.60.21.10
DomainConA-like_dom

FAT3 CNTNAP1 ADGRV1 MEP1A FAT2 LRBA USH2A

1.98e-032191507IPR013320
DomainEF_HAND_2

CRACR2A GUCA1A ANKEF1 RHBDL3 NECAB3 PLCG1 EFCAB7

2.67e-032311507PS50222
DomainEF_hand_dom

CRACR2A GUCA1A ANKEF1 RHBDL3 NECAB3 PLCG1 EFCAB7

2.73e-032321507IPR002048
DomainLeu-rich_rpt_4

LRRIQ4 LRR1

2.76e-03101502IPR025875
DomainSugar_P_trans_dom

SLC35D2 SLC35D1

2.76e-03101502IPR004853
DomainMKP

DUSP8 DUSP16

2.76e-03101502IPR008343
DomainLRR_4

LRRIQ4 LRR1

2.76e-03101502PF12799
DomainTPT

SLC35D2 SLC35D1

2.76e-03101502PF03151
DomainMFS_sugar_transport-like

SLC22A16 SV2B SLC22A13

2.99e-03361503IPR005828
DomainSugar_tr

SLC22A16 SV2B SLC22A13

2.99e-03361503PF00083
DomainMFS_1

SLC17A3 SV2B SLC22A13 SLC45A1

3.43e-03771504PF07690
DomainMFS

SLC17A3 SV2B SLC22A13 SLC45A1

3.43e-03771504IPR011701
DomainTPR_repeat

TTC27 TMTC1 PPP5C GPSM2 ZC3H7B

4.41e-031331505IPR019734
DomainEF-hand_7

CRACR2A GUCA1A RHBDL3 EFCAB7

4.89e-03851504PF13499
Domain-

CRACR2A GUCA1A ANKEF1 RHBDL3 NECAB3 PLCG1 EFCAB7

5.20e-0326115071.10.238.10
DomainTUDOR

TDRKH RNF17

5.47e-03141502PF00567
Pubmed

Early development of electrical excitability in the mouse enteric nervous system.

SCN5A SCN8A SCN9A

8.13e-075152322875929
Pubmed

Simultaneous mutation detection in 90 retinal disease genes in multiple patients using a custom-designed 300-kb retinal resequencing chip.

ADGRV1 PRPF8 CFB GUCA1A C2 USH2A

2.38e-0687152620801516
Pubmed

The collagen derived dipeptide hydroxyprolyl-glycine promotes C2C12 myoblast differentiation and myotube hypertrophy.

SLC15A2 MTOR SLC15A4

2.83e-067152327553280
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN5A SCN8A SCN9A

6.74e-069152316382098
Pubmed

Significance of C2/CFB variants in age-related macular degeneration and polypoidal choroidal vasculopathy in a Japanese population.

CFB C2

1.90e-052152222232432
Pubmed

The molecular genetics and polymorphism of C2 and factor B.

CFB C2

1.90e-05215223315100
Pubmed

PML colocalizes with and stabilizes the DNA damage response protein TopBP1.

TOPBP1 PML

1.90e-052152212773567
Pubmed

A targeted disruption of the murine complement factor B gene resulting in loss of expression of three genes in close proximity, factor B, C2, and D17H6S45.

CFB C2

1.90e-05215229430715
Pubmed

dCK expression correlates with 5-fluorouracil efficacy and HuR cytoplasmic expression in pancreatic cancer: a dual-institutional follow-up with the RTOG 9704 trial.

DCK ELAVL1

1.90e-052152224618665
Pubmed

HuR-mediated SCN5A messenger RNA stability reduces arrhythmic risk in heart failure.

SCN5A ELAVL1

1.90e-052152229454929
Pubmed

Associations of complement factor B and complement component 2 genotypes with subtypes of polypoidal choroidal vasculopathy.

CFB C2

1.90e-052152224965207
Pubmed

Vav1 oncogenic mutation inhibits T cell receptor-induced calcium mobilization through inhibition of phospholipase Cγ1 activation.

PLCG1 VAV1

1.90e-052152222474331
Pubmed

mTOR-dependent regulation of PHLPP expression controls the rapamycin sensitivity in cancer cells.

MTOR PHLPP1

1.90e-052152221177869
Pubmed

NGL-3 in the regulation of brain development, Akt/GSK3b signaling, long-term depression, and locomotive and cognitive behaviors.

LRRC4B LRRC4C

1.90e-052152231166939
Pubmed

Restriction fragment length polymorphism analysis of factor B and C2 genes in H-2 recombinant mouse strains.

CFB C2

1.90e-05215221970336
Pubmed

Murine complement C2 and factor B genomic and cDNA cloning reveals different mechanisms for multiple transcripts of C2 and B.

CFB C2

1.90e-05215222229060
Pubmed

The involvement of complement factor B and complement component C2 in an Indian cohort with age-related macular degeneration.

CFB C2

1.90e-052152219696172
Pubmed

SCP phosphatases suppress renal cell carcinoma by stabilizing PML and inhibiting mTOR/HIF signaling.

MTOR PML

1.90e-052152225293974
Pubmed

Protective effect of complement factor B and complement component 2 variants in age-related macular degeneration.

CFB C2

1.90e-052152217576744
Pubmed

Sodium channel slow inactivation interferes with open channel block.

SCN8A SCN9A

1.90e-052152227174182
Pubmed

Disease expression in Usher syndrome caused by VLGR1 gene mutation (USH2C) and comparison with USH2A phenotype.

ADGRV1 USH2A

1.90e-052152215671307
Pubmed

Characteristics of Retinitis Pigmentosa Associated with ADGRV1 and Comparison with USH2A in Patients from a Multicentric Usher Syndrome Study Treatrush.

ADGRV1 USH2A

1.90e-052152234638692
Pubmed

Molecular cloning, structural analysis and expression of complement component Bf/C2 genes in the nurse shark, Ginglymostoma cirratum.

CFB C2

1.90e-052152217482263
Pubmed

The association between complement component 2/complement factor B polymorphisms and age-related macular degeneration: a HuGE review and meta-analysis.

CFB C2

1.90e-052152222869612
Pubmed

SLC15A2 and SLC15A4 Mediate the Transport of Bacterially Derived Di/Tripeptides To Enhance the Nucleotide-Binding Oligomerization Domain-Dependent Immune Response in Mouse Bone Marrow-Derived Macrophages.

SLC15A2 SLC15A4

1.90e-052152229784761
Pubmed

Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5.

SCN5A SCN9A

1.90e-052152226861708
Pubmed

Usher's Syndrome Type II: A Comparative Study of Genetic Mutations and Vestibular System Evaluation.

ADGRV1 USH2A

1.90e-052152228653555
Pubmed

Divergent developmental expression and function of the proton-coupled oligopeptide transporters PepT2 and PhT1 in regional brain slices of mouse and rat.

SLC15A2 SLC15A4

1.90e-052152224548120
Pubmed

Upstream sequence elements enhance poly(A) site efficiency of the C2 complement gene and are phylogenetically conserved.

CFB C2

1.90e-05215227641699
Pubmed

Analysis of rare variants in the complement component 2 (C2) and factor B (BF) genes refine association for age-related macular degeneration (AMD).

CFB C2

1.90e-052152218806293
Pubmed

A circular RNA derived from FAT atypical cadherin 3 promotes lung cancer progression via forming a regulatory loop with oncogenic ELAV like RNA binding protein 1.

FAT3 ELAVL1

1.90e-052152234647573
Pubmed

ZDHHC22-mediated mTOR palmitoylation restrains breast cancer growth and endocrine therapy resistance.

MTOR ZDHHC22

1.90e-052152235541896
Pubmed

Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration.

CFB C2

1.90e-052152216518403
Pubmed

Cell-specific expression of the human complement protein factor B gene: evidence for the role of two distinct 5'-flanking elements.

CFB C2

1.90e-05215223643061
Pubmed

PML mediates glioblastoma resistance to mammalian target of rapamycin (mTOR)-targeted therapies.

MTOR PML

1.90e-052152223440206
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN5A SCN8A SCN9A

2.27e-0513152315123669
Pubmed

Congenital hypomyelinating neuropathy with lethal conduction failure in mice carrying the Egr2 I268N mutation.

NAB1 CNTNAP1 SCN8A

2.88e-0514152319244508
Pubmed

Enoyl-CoA hydratase-1 regulates mTOR signaling and apoptosis by sensing nutrients.

PSMD1 ECPAS MTOR

2.88e-0514152328878358
Pubmed

PML nuclear bodies contribute to the basal expression of the mTOR inhibitor DDIT4.

MTOR PML

5.68e-053152228332630
Pubmed

Prognostic effect of hENT1, dCK and HuR expression by morphological type in periampullary adenocarcinoma, including pancreatic cancer.

DCK ELAVL1

5.68e-053152226362587
Pubmed

The Role of Deoxycytidine Kinase (dCK) in Radiation-Induced Cell Death.

DCK MTOR

5.68e-053152227879648
Pubmed

Complement C4bC2 complex formation: an investigation by surface plasmon resonance.

CFB C2

5.68e-053152211341920
Pubmed

PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome.

ADGRV1 USH2A

5.68e-053152220440071
Pubmed

Essential role of factor B of the alternative complement pathway in complement activation and opsonophagocytosis during acute pneumococcal otitis media in mice.

CFB C2

5.68e-053152221502587
Pubmed

Complement C3, C2, and factor B gene polymorphisms and age-related macular degeneration in a Greek cohort study.

CFB C2

5.68e-053152224519512
Pubmed

Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes.

FAT3 FAT2

5.68e-053152215744052
Pubmed

Decreased ZMIZ1 suppresses melanogenesis in vitiligo by regulating mTOR/AKT/GSK-3β-mediated glucose uptake.

ZMIZ1 MTOR

5.68e-053152238117454
Pubmed

CENP-C and CENP-I are key connecting factors for kinetochore and CENP-A assembly.

CENPC CENPI

5.68e-053152226527398
Pubmed

Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C.

PLCG1 VAV1

5.68e-053152211956228
Pubmed

Germline TYMS genotype is highly predictive in patients with metastatic gastrointestinal malignancies receiving capecitabine-based chemotherapy.

DPYD GSTP1

5.68e-053152225677447
Pubmed

Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα).

CHUK MTOR

5.68e-053152224990947
Pubmed

Expression profile and functional activity of peptide transporters in prostate cancer cells.

SLC15A2 SLC15A4

5.68e-053152222950754
Pubmed

Targeting the NF-κB and mTOR pathways with a quinoxaline urea analog that inhibits IKKβ for pancreas cancer therapy.

CHUK MTOR

5.68e-053152223444213
Pubmed

Nuclear phospholipase C gamma: punctate distribution and association with the promyelocytic leukemia protein.

PLCG1 PML

5.68e-053152217419608
Pubmed

Non-USH2A mutations in USH2 patients.

ADGRV1 USH2A

5.68e-053152222147658
Pubmed

Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-gamma1-driven activation of mTOR/p70S6-kinase pathway.

MTOR PLCG1

5.68e-053152219881535
Pubmed

Accelerated nephrotoxic nephritis is exacerbated in C1q-deficient mice.

CFB C2

5.68e-053152211359841
Pubmed

Next-generation sequencing to solve complex inherited retinal dystrophy: A case series of multiple genes contributing to disease in extended families.

PRPF8 USH2A

5.68e-053152228761320
Pubmed

Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity.

PPP5C MTOR

5.68e-053152215218033
Pubmed

Cutting edge: C1q protects against the development of glomerulonephritis independently of C3 activation.

CFB C2

5.68e-053152210229798
Pubmed

Pml represses tumour progression through inhibition of mTOR.

MTOR PML

5.68e-053152221387562
Pubmed

Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents.

SCN5A SCN9A

5.68e-053152220038812
Pubmed

RNA Binding Protein, HuR, Regulates SCN5A Expression Through Stabilizing MEF2C transcription factor mRNA.

SCN5A ELAVL1

5.68e-053152229678826
Pubmed

Enhanced susceptibility to acute pneumococcal otitis media in mice deficient in complement C1qa, factor B, and factor B/C2.

CFB C2

5.68e-053152220065024
Pubmed

Targeted next generation sequencing in Italian patients with Usher syndrome: phenotype-genotype correlations.

ADGRV1 USH2A

5.68e-053152229142287
Pubmed

Association of polymorphisms in C2, CFB and C3 with exudative age-related macular degeneration in a Korean population.

CFB C2

5.68e-053152222273503
Pubmed

The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1.

ADGRV1 USH2A

5.68e-053152216434480
Pubmed

The proton-coupled oligopeptide transporters PEPT2, PHT1 and PHT2 mediate the uptake of carnosine in glioblastoma cells.

SLC15A2 SLC15A4

5.68e-053152231073693
Pubmed

Expression of alternatively spliced sodium channel alpha-subunit genes. Unique splicing patterns are observed in dorsal root ganglia.

SCN8A SCN9A

5.68e-053152215302875
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

DPYD ACACA ECPAS PRPF8 DDB1 SLITRK1 TTC6 SCN9A COPS7B LRBA

7.14e-054971521036774506
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ACACA TTC27 PSMD1 PPP6R1 ZMIZ1 ECPAS ZFHX4 LRP2 LRBA

9.93e-05418152934709266
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

DLG5 ZNF862 URB1 PHLPP1 AQR

1.01e-0410515259628581
Pubmed

Association between polymorphisms of complement pathway genes and age-related macular degeneration in a Chinese population.

CFB C2

1.13e-044152223233260
Pubmed

Usher syndromes due to MYO7A, PCDH15, USH2A or GPR98 mutations share retinal disease mechanism.

ADGRV1 USH2A

1.13e-044152218463160
Pubmed

Ablation of whirlin long isoform disrupts the USH2 protein complex and causes vision and hearing loss.

ADGRV1 USH2A

1.13e-044152220502675
Pubmed

Differential involvement of IkappaB kinases alpha and beta in cytokine- and insulin-induced mammalian target of rapamycin activation determined by Akt.

CHUK MTOR

1.13e-044152218490760
Pubmed

Association Between Complement Factor C2/C3/CFB/CFH Polymorphisms and Age-Related Macular Degeneration: A Meta-Analysis.

CFB C2

1.13e-044152230179527
Pubmed

Usher Syndrome Type II

ADGRV1 USH2A

1.13e-044152220301515
Pubmed

Reduced AMPK-ACC and mTOR signaling in muscle from older men, and effect of resistance exercise.

ACACA MTOR

1.13e-044152223000302
Pubmed

The underlying mechanism of proinflammatory NF-κB activation by the mTORC2/Akt/IKKα pathway during skin aging.

CHUK MTOR

1.13e-044152227486771
Pubmed

The proton oligopeptide cotransporter family SLC15 in physiology and pharmacology.

SLC15A2 SLC15A4

1.13e-044152212905028
Pubmed

Subdivision of the S region of the mouse major histocompatibility complex by identification of genomic polymorphisms of the class III genes.

CFB C2

1.13e-04415226088393
Pubmed

PPDPF alleviates hepatic steatosis through inhibition of mTOR signaling.

DDB1 MTOR

1.13e-044152234031390
Pubmed

Divergent outer retinal circuits drive image and non-image visual behaviors.

GJD2 ELFN1

1.13e-044152235767957
Pubmed

Impaired opsonization with C3b and phagocytosis of Streptococcus pneumoniae in sera from subjects with defects in the classical complement pathway.

CFB C2

1.13e-044152218541650
Pubmed

C2 and CFB genes in age-related maculopathy and joint action with CFH and LOC387715 genes.

CFB C2

1.13e-044152218493315
Pubmed

[Polymorphisms of complement factor genes and age-related macular degeneration in a German population].

CFB C2

1.13e-044152219399715
Pubmed

Adenylyl cyclase 6 plays a minor role in the mouse inner ear and retina.

ADGRV1 USH2A

1.13e-044152237127773
Pubmed

Individual USH2 proteins make distinct contributions to the ankle link complex during development of the mouse cochlear stereociliary bundle.

ADGRV1 USH2A

1.13e-044152226401052
Pubmed

Deafness-Associated ADGRV1 Mutation Impairs USH2A Stability through Improper Phosphorylation of WHRN and WDSUB1 Recruitment.

ADGRV1 USH2A

1.13e-044152237066759
Pubmed

Further assessment of the complement component 2 and factor B region associated with age-related macular degeneration.

CFB C2

1.13e-044152218806297
Pubmed

Proton-coupled oligopeptide transporter (POT) family expression in human nasal epithelium and their drug transport potential.

SLC15A2 SLC15A4

1.13e-044152221366347
Pubmed

The mRNA-stabilizing factor HuR protein is targeted by β-TrCP protein for degradation in response to glycolysis inhibition.

CHUK ELAVL1

1.13e-044152223115237
Pubmed

Localization of PDZD7 to the stereocilia ankle-link associates this scaffolding protein with the Usher syndrome protein network.

ADGRV1 USH2A

1.13e-044152223055499
Pubmed

PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR.

MTOR PML

1.13e-044152216915281
Pubmed

Role of RDBP and SKIV2L variants in the major histocompatibility complex class III region in polypoidal choroidal vasculopathy etiology.

CFB C2

1.13e-044152219556007
Pubmed

Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells.

ACACA MTOR

1.13e-044152217631500
Pubmed

Whirlin and PDZ domain-containing 7 (PDZD7) proteins are both required to form the quaternary protein complex associated with Usher syndrome type 2.

ADGRV1 USH2A

1.13e-044152225406310
Pubmed

Nuclear association of tyrosine-phosphorylated Vav to phospholipase C-gamma1 and phosphoinositide 3-kinase during granulocytic differentiation of HL-60 cells.

PLCG1 VAV1

1.13e-04415229891995
Pubmed

Orientation and molecular map position of the complement genes in the mouse MHC.

CFB C2

1.13e-04415223034587
CytobandEnsembl 112 genes in cytogenetic band chr15q14

SLC12A6 GJD2 PGBD4 AQR

5.20e-05611524chr15q14
GeneFamilySolute carriers

SLC12A6 SLC17A3 SLC35D2 SLC10A4 SLC19A2 SLCO6A1 SLC35D1 SLC6A1 SLC22A16 SLC15A2 SLC15A4 SLC22A13 SLC10A5 SLC45A1 SLC33A1

2.44e-0839511315752
GeneFamilySodium voltage-gated channel alpha subunits

SCN5A SCN8A SCN9A

1.94e-05911331203
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TTC27 TTC6 TMTC1 PPP5C GPSM2 ZC3H7B

8.44e-051151136769
GeneFamilyCadherin related

CDHR1 FAT3 FAT2

1.52e-0417113324
GeneFamilyFibronectin type III domain containing|USH2 complex

ADGRV1 USH2A

2.30e-04411321244
GeneFamilyEF-hand domain containing

CRACR2A GUCA1A ANKEF1 RHBDL3 NECAB3 PLCG1 EFCAB7

4.53e-042191137863
GeneFamilyTudor domain containing

TDRKH RNF17 UHRF2

1.58e-03371133780
GeneFamilyMAP kinase phosphatases

DUSP8 DUSP16

2.05e-03111132895
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM FAT3 LRRC4C ADGRV1 ZFHX4 SCN9A LRP2 USH2A

2.38e-0718415282cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM FAT3 LRRC4C ADGRV1 ZFHX4 SCN9A LRP2 USH2A

2.38e-071841528ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM FAT3 LRRC4C ADGRV1 ZFHX4 SCN9A LRP2 USH2A

2.38e-0718415282b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-Child09-12-SmallIntestine-Epithelial-epithelial_progenitor_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP5MC3 IFT172 CDHR1 ATP10B GSTP1 MGST2 PGAP1 PKP2

3.57e-07194152846e522ca59db545d1eb0c27cd4361f19d4f8f762
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Intermediate|GW23 / Sample Type, Dataset, Time_group, and Cell type.

SLC35D2 CDHR1 CNTNAP1 SEMA3G URB1 ANKRD13C ANKEF1 USH2A

4.49e-072001528fe772d98c461c973dfc082e1fc50117c27ced804
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM CPN2 CFB MEP1A CHPT1 SLC15A2 SLC22A13

1.83e-061681527b14fd50232887b6dca1f39014d43c6f66e5c3b5c
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AGPAT5 PLCXD1 PPP6R1 URB1 GUCA1A VAV1 NCKAP1L

1.91e-061691527305cedbd97059029d7d2a248a8a4b6cfe281aa54
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP5MC3 FAT3 ADGRV1 RNF17 SCN9A LRP2 USH2A

1.91e-06169152712bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellfacs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 MEP1A CHPT1 SLC15A2 SLC22A13 LRP2 SLC33A1

2.40e-061751527076ad81d6cbeea5512393d192af3ab5aa1f82975
ToppCellfacs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 MEP1A CHPT1 SLC15A2 SLC22A13 LRP2 SLC33A1

2.40e-061751527445ccb9744a3a9ff37164c532afbe769d306b6c8
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCK LRR1 ANP32E ATP13A3 PARPBP EFCAB7 RUFY4

3.12e-06182152721dcab170ffeef89faa9fee5008568cb6e15c694
ToppCellCOPD-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

SLC12A6 NAB1 PGAP1 DUSP16 PHLPP1 ATP13A3 UHRF2

4.28e-0619115273ae18bc4e3dff49b5d5958da8ebc3f747274b69c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANKRD29 CDHR1 SLC10A4 ITGA8 SLC6A1 ELFN1 PKP2

4.43e-0619215276a252e298f8a454623fa9c1c893a7a45a886d694
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP5MC3 IFT172 CDHR1 ATP10B GSTP1 PGAP1 PKP2

5.25e-061971527c0250509836f1be04f5e54386191d7bb1e1da652
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DLG5 SLCO6A1 TTC6 FAT2 FRMD6 PKP2 TRPV4

5.25e-0619715271e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCellCOVID-19-COVID-19_Severe-Myeloid-pDC|COVID-19_Severe / Disease, condition lineage and cell class

CXCR3 DCK MGST2 SLC15A4 UGCG SCN9A RUFY4

5.42e-061981527033ed362333e1d33f2aeea8da5865d2228d154dc
ToppCellSepsis-Leuk-UTI-Myeloid-pDC|Leuk-UTI / Disease, condition lineage and cell class

CXCR3 DCK FMNL3 MGST2 SLC15A4 UGCG SCN9A

5.61e-0619915272f8d297afd26ae1e9fb66d8573274452c4133b6c
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DLG5 CDHR1 SLCO6A1 FAT2 FRMD6 PGAP1 TRPV4

5.79e-0620015278827653738a931e4a4545e0c7d75be12bed40740
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP1 ITGA8 RNF17 FMNL3 TMTC1 RHBDL3

1.20e-051481526f85dc34f6a4a15ecffa4fbd5644dea12ce30089b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP1 ITGA8 RNF17 FMNL3 TMTC1 RHBDL3

1.20e-0514815264b1fdf90c585f89cee1cf521db4e3fafc9d74d9a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP1 ITGA8 RNF17 FMNL3 TMTC1 RHBDL3

1.20e-05148152655826b7e9f79ab78a93abd4fc662bc37aa121471
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH11 FAT3 ADGRV1 ZFHX4 LRP2 USH2A

1.86e-051601526c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellCOVID_non-vent-Lymphocytic-Dendritic-pDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

CXCR3 DCK SLC15A4 UGCG SCN9A RUFY4

1.86e-05160152661f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCellCOVID_non-vent-Lymphocytic-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

CXCR3 DCK SLC15A4 UGCG SCN9A RUFY4

1.86e-05160152634b4f710cfcb6ec370b8b074f3cbfe272f392cec
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH11 FAT3 ADGRV1 ZFHX4 LRP2 USH2A

1.86e-05160152625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 ACOX1 CFB MEP1A CHPT1 LRP2

2.21e-051651526082f62f759a0b16ab56fad6dd4c4dd70b4f18a5c
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 ACOX1 CFB MEP1A CHPT1 LRP2

2.29e-0516615268ab18c9d911eb3a9970bba7a769294b0927538f7
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 ACOX1 CFB MEP1A CHPT1 LRP2

2.29e-0516615260868f45d8d39ad39b5cee5e81ac3dd4dc512775d
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 MEP1A SLC15A2 SLC22A13 LRP2 USH2A

2.37e-051671526ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCelldroplet-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 ACOX1 CFB MEP1A CHPT1 LRP2

2.45e-051681526dd48da83c32d41a62f80cd7e5e5c64e42776fa27
ToppCelldroplet-Kidney-nan-18m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 MEP1A SLC15A2 SLC22A13 LRP2 USH2A

2.53e-051691526f00741203efa0b948db7223ee8c19bdd0918258a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A16 CENPI GPSM2 PARPBP VAV1 NCKAP1L

2.53e-05169152654b13ab02b4c187f4754045ecfcf409749e7ccc0
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TOPBP1 LRR1 URB1 NECAB3 PARPBP EFCAB7

2.62e-051701526badbe200e9d5003d23d115955b10b4ea767f6c26
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SECISBP2L ACACA ADGRV1 TTC6 CHPT1 NECAB3

2.62e-051701526a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCelldroplet-Kidney-nan-3m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 MEP1A CHPT1 SLC15A2 SLC22A13 LRP2

2.62e-051701526dd48fd3c5c67eb71183981f42975a538f12077c3
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYH11 ITGA8 TMC4 ABCA9 SLC6A1 CENPI

2.71e-051711526a4a2c5dc995589fbe3d4ca6ee1df888807e4ae34
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 ACOX1 CFB MEP1A CHPT1 LRP2

2.71e-05171152648fc4eca18b102b5ec5050f758281292ee8e10c6
ToppCelldroplet-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 ACOX1 CFB MEP1A CHPT1 LRP2

2.71e-05171152605fcc72df50a380a913821b5781d9621df37d328
ToppCellmetastatic_Lymph_Node-Myeloid_cells-pDCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

CNTNAP1 GUCA1A SLC15A4 UGCG SCN9A RUFY4

2.71e-0517115261f8e66073088fc1969782e443bf00f8c1877ea91
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD29 ATP5MC3 RNF17 GSTP1 LRP2 USH2A

2.89e-05173152666f37c1437705734b20601656fa4aa1d92ca30be
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKRD29 ATP5MC3 RNF17 GSTP1 LRP2 USH2A

2.89e-051731526649b08a409095592cccf31883be69c754411280d
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 ACOX1 CFB MEP1A CHPT1 LRP2

3.08e-05175152613843bfc8efe7c01f19ebb6735609c1eec09c698
ToppCellfacs-BAT-Fat-3m-Epithelial|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC6 AGBL3 SLC10A5 GNB5 PKP2 SYT5

3.28e-0517715263e42f6236962dd9bb23dc0d09b460ec8347d1056
ToppCellfacs-BAT-Fat-3m-Epithelial-epithelial_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC6 AGBL3 SLC10A5 GNB5 PKP2 SYT5

3.28e-051771526128186bc996784e670194c07c5352e69af5f6d68
ToppCellMild/Remission-B_memory-6|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CXCR3 SLC35D2 ACP5 CDC42EP3 ATP6V0D1 TMEM238

3.28e-0517715268f2ce5ffc94ca90412cb6899629f322dc778215c
ToppCellfacs-BAT-Fat-3m-Epithelial-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC6 AGBL3 SLC10A5 GNB5 PKP2 SYT5

3.28e-0517715267480e522cfae3f5c6c62720083750f8273725ab5
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MYH11 LRRC4C RGL1 ZFHX4 MGST2 UGCG

3.50e-05179152614fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellICU-NoSEP-Myeloid-tDC|ICU-NoSEP / Disease, Lineage and Cell Type

CXCR3 ZNF862 MGST2 FRMD6 UGCG SCN9A

3.61e-051801526be665e801512f6aaf6b3ecb26153bbdeb24619ac
ToppCellControl-Lymphoid-T_Regulatory|World / Disease state, Lineage and Cell class

CXCR3 NAB1 PGAP1 DUSP16 LRBA UHRF2

3.61e-05180152647036eee4c128fbb443d1fc767b4de5cced93f0e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANKRD29 SLC10A4 ITGA8 SLC6A1 ELFN1 PKP2

3.72e-05181152635bcdcd2651149692e5b150e887c0f450c81d2d4
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ITGA8 SLC6A1 TMTC1 ELFN1 SCN5A SCN9A

3.72e-051811526153709b4dd3d81e09f251fa8765b58bed1932fda
ToppCellmetastatic_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

CXCR3 CNTNAP1 GUCA1A SLC15A4 UGCG SCN9A

3.84e-05182152602e04294fce12591c32d7bd0e866a000ad1f836e
ToppCellControl-Lymphoid-T_Regulatory|Control / Disease state, Lineage and Cell class

CXCR3 NAB1 PGAP1 DUSP16 LRBA UHRF2

3.84e-05182152631bb838cc2900f3c9da9f835d79d557a08abb928
ToppCell(7)_DC_plasmacytoid|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

CXCR3 GUCA1A MGST2 SLC15A4 UGCG SCN9A

3.95e-0518315262c6475c935b5a90931be6b3c53f1f707cfcd11f4
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANKRD29 FAT3 LRRC4C SV2B RHBDL3 SCN9A

4.08e-0518415266475a43201b136dcc9b113d2ca4cfa154ed9d65d
ToppCellControl-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

SLC12A6 NAB1 PGAP1 DUSP16 PHLPP1 ATP13A3

4.20e-051851526e481cacda0b6b25f5f0062b962df9a442053ac30
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANKRD29 SLC10A4 ITGA8 SLC6A1 ELFN1 PKP2

4.60e-0518815266ee3f8f94ea7bdf652c9575fc65bff08070093a4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANKRD29 GJD2 SEMA3G FMNL3 TMTC1 ATP13A3

4.60e-051881526c2c51c6526defe2600302901159b8abbb58d7595
ToppCellmyeloid-pDC|myeloid / Lineage and Cell class

CXCR3 DCK FMNL3 SLC15A4 UGCG SCN9A

4.60e-051881526a2dc4bbeca2bdc00c51825dd65a699c54c72f241
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

AGPAT5 CENPC PGAP1 LPAR2 LRBA UHRF2

4.87e-05190152691ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma-erythroid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FAT3 CFB RGL1 ZFHX4 RHBDL3 C2

4.87e-051901526cf463b2f227f3cc7d3fd296c810c0cbe51cbee72
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANKRD29 SLC10A4 SLC6A1 ELFN1 SCN5A PKP2

5.02e-051911526764c3a8829ae1253a0790744138266e81fc075ec
ToppCellControl-Myeloid-pDC|Control / Disease, Lineage and Cell Type

CXCR3 DCK MGST2 SLC15A4 UGCG SCN9A

5.02e-051911526473f904fe244d919ce561139591a2be12cc9fa6b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANKRD29 SLC10A4 ITGA8 SLC6A1 ELFN1 PKP2

5.17e-0519215263abee376c37c3646da33ac381aa63d50a01607a6
ToppCellrenal_papilla_nuclei-Adult_normal_reference|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

MGAM FAT3 ITGA8 TMTC1 CHPT1 LRBA

5.17e-0519215266c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ANKRD29 ADGRV1 TTC6 LRP2 SYT5 TMEM238

5.17e-0519215268898332387e5d746feb346ce1dabd6b2218fc6e5
ToppCell(5)_Fibroblasts-(5)_Fibroblast-J_(Lipofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

CFB UGCG SCN9A LRP2 PKP2 C2

5.47e-051941526784b15119c91ace33d34bfb3d68c182566a3e9a8
ToppCell3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IFT172 CDHR1 ATP10B MGST2 PGAP1 PKP2

5.63e-051951526b67d4f34cae729c18275486d3b20c9dd7d5cbe79
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IFT172 CDHR1 ATP10B GSTP1 PGAP1 PKP2

5.79e-05196152697324c9e93f833e1f218e81fb53066d44c6892df
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CRACR2A SLC6A1 FAT2 SLC15A2 SCN8A TRPV4

6.13e-05198152628ada093cec552262731194a04a4b9ff93186c3b
ToppCell(5)_Dendritic_cell-(54)_pDC|(5)_Dendritic_cell / shred on Cell_type and subtype

CXCR3 GUCA1A SLC15A4 GNB5 UGCG SCN9A

6.13e-051981526fc6c6b60dddd7f2f997af0f87fae33f1c23f34a8
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

CENPC LRR1 CENPI ANP32E GPSM2 PARPBP

6.13e-051981526629d674a9c9108c1acb3f7af57bbdbf34bb0528e
ToppCellTracheal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MYH11 FAT3 LRRC4B PKD2L2 SCN5A SLC45A1

6.13e-051981526cbb63b255bdc92a557c5db1f08f7766ed9346607
ToppCellSepsis-Leuk-UTI-Others|Leuk-UTI / Disease, condition lineage and cell class

CXCR3 DCK FMNL3 SLC15A4 UGCG SCN9A

6.30e-051991526e45fe91f1d1c47a305b0f39d808730723852af00
ToppCellSepsis-ICU-NoSEP-Myeloid-tDC|ICU-NoSEP / Disease, condition lineage and cell class

CXCR3 ZNF862 MGST2 FRMD6 UGCG SCN9A

6.30e-05199152690ddd686b8f39c6f6134b9b048396cebcf8d0448
ToppCellMS-IIF-Myeloid-pDC|IIF / Disease, condition lineage and cell class

CXCR3 FMNL3 MGST2 SLC15A4 UGCG SCN9A

6.30e-051991526e262ee854e64d87460bee810c14d6cbe744460e8
ToppCellSepsis-Leuk-UTI-Others-RBC|Leuk-UTI / Disease, condition lineage and cell class

CXCR3 DCK FMNL3 SLC15A4 UGCG SCN9A

6.30e-051991526d9b517199a646c9461c615412ad5b58cf4bed7c8
ToppCell356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ACP5 CFB ZFHX4 UGCG PKP2 C2

6.30e-051991526f4fdf94c561dca35bb17766d908c5030655f43eb
ToppCellControl-Control-Myeloid-pDC|Control / Disease, condition lineage and cell class

CXCR3 DCK MGST2 SLC15A4 UGCG SCN9A

6.30e-0519915268e9cac53fabe497ffa27fca0627eafe883af2534
ToppCellCOVID-19-COVID-19_Mild-Myeloid-pDC|COVID-19_Mild / Disease, condition lineage and cell class

CXCR3 DCK MGST2 SLC15A4 UGCG SCN9A

6.30e-0519915269de61e5189d907cc969ac3043d68204f70acc0bf
ToppCell356C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ACP5 CFB ZFHX4 UGCG PKP2 C2

6.30e-051991526c0fe99ed906d0eb99cccdab9a1fa32c17b3542e7
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ITGA8 ABCA9 FMNL3 RGL1 TMTC1 ZFHX4

6.48e-052001526a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ACACA CRACR2A TMC4 ADGRV1 TTC6 TRPV4

6.48e-052001526d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANKRD29 SLC10A4 ITGA8 SLC6A1 ELFN1 PKP2

6.48e-0520015267e51715525fdb001b7042b2bfcb9de81ecb5e4ee
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SECISBP2L ADGRV1 GOLT1A LRP2 C2 TMEM238

6.48e-052001526acc771a902cf2f060c3eb9aedb72a256f5778a6c
ToppCellParenchyma_COVID-19-Epithelial-TX-AT2-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

SECISBP2L ADGRV1 GOLT1A LRP2 C2 TMEM238

6.48e-052001526ceb613ac6cdf0e3e6bb3f04d89034e18a524cefb
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_2|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANKRD29 SLC10A4 ITGA8 SLC6A1 ELFN1 PKP2

6.48e-052001526913487e065dd580c9cbcbb3c3fc76a8d446f8856
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SECISBP2L ADGRV1 GOLT1A LRP2 C2 TMEM238

6.48e-052001526eb44d1f80ecaac3a022cd04ab16dc36151e45488
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)|Neuronal / cells hierarchy compared to all cells using T-Statistic

ANKRD29 SLC10A4 ITGA8 SLC6A1 ELFN1 PKP2

6.48e-05200152675649534a98bc738fca62d071de0978dc61eb24f
ToppCell(54)_pDC|World / shred on Cell_type and subtype

CXCR3 GUCA1A MGST2 SLC15A4 UGCG SCN9A

7.03e-052031526b8ba3e51770ff7b45cd02472f3e63aa4d5816f6f
ToppCellfacs-Liver-Hepatocytes-3m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 ACOX1 SLC19A2 CPN2 GOLT1A

1.15e-04139152582bf5ba69a907fbd9b4e2b2dd1dd27b8c4c75f25
ToppCellfacs-Liver-Hepatocytes-3m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 ACOX1 SLC19A2 CPN2 GOLT1A

1.15e-041391525fc9ac09c2106e88104a52575832d71d17765eec8
ToppCellfacs-Liver-Hepatocytes-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 ACOX1 SLC19A2 CPN2 GOLT1A

1.15e-041391525fc4b39ac9a10cf0acacfebbc4295edf324d930d5
ToppCellfacs-Liver-Hepatocytes-3m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 ACOX1 SLC19A2 CPN2 GOLT1A

1.15e-0413915254ddfbc36a0560fb70594627178bff652ab1ea3e9
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMC4 TMBIM1 CHUK SLC22A16 SYT5

1.31e-0414315258f897278f9ccc82ae35e4f30c5f930b2a3eb509d
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|390C / Donor, Lineage, Cell class and subclass (all cells)

CXCR3 CDHR1 SEMA3G CDC42EP3 SYT5

1.31e-041431525d877d914e4e74db2053baa310d318d6440e672bc
ToppCellfrontal_cortex-Non-neuronal-macrophage-Macrophage-PVM_Mrc1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CXCR3 ABCA9 C2 TRPV4 NCKAP1L

1.54e-041481525d3ea907f8f408e9bb97ed223a3089e403e35f911
ToppCellSubstantia_nigra-Hematopoietic-MICROGLIA|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GUCA1A CENPI PARPBP VAV1 NCKAP1L

1.64e-041501525d44c02402e59a45e40b8fffbe71284032b5e7c92
ToppCellSubstantia_nigra-Hematopoietic-MICROGLIA-MI2(C1qb)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GUCA1A CENPI PARPBP VAV1 NCKAP1L

1.64e-041501525e020dbcf85c0ba7ad667b8bbeb6bbcfc135c9bb7
ToppCellSubstantia_nigra-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GUCA1A CENPI PARPBP VAV1 NCKAP1L

1.64e-041501525edbc1d29d213bf5908592135700e0d80e123c923
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN5A SCN8A SCN9A

1.45e-05101483DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN5A SCN8A SCN9A

1.45e-05101483DOID:0080422 (implicated_via_orthology)
DiseaseMACULAR DEGENERATION, AGE-RELATED, 14

CFB C2

2.50e-0521482C3809653
DiseaseAge related macular degeneration 14

CFB C2

2.50e-0521482cv:C3809653
Diseaseage related macular degeneration 14 (is_implicated_in)

CFB C2

2.50e-0521482DOID:0110026 (is_implicated_in)
DiseaseMACULAR DEGENERATION, AGE-RELATED, 14

CFB C2

2.50e-0521482615489
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN5A SCN8A SCN9A

2.63e-05121483DOID:0060170 (implicated_via_orthology)
DiseaseB Virus Infection

SCN8A SCN9A

7.47e-0531482C0037140
DiseasePostherpetic neuralgia

SCN8A SCN9A

7.47e-0531482C0032768
DiseaseHerpesviridae Infections

SCN8A SCN9A

7.47e-0531482C0019372
DiseaseArrhythmogenic Right Ventricular Dysplasia

SCN5A PKP2

7.47e-0531482C0349788
Diseasealpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase measurement

LRR1 CHPT1

2.47e-0451482EFO_0801370
Diseaserevision of total knee arthroplasty

AGPAT5 MDH1B IP6K2

2.95e-04261483EFO_0020972
Diseasechildhood trauma measurement, alcohol consumption measurement

PCDHGB1 LRRC4C DCK SLCO6A1

4.55e-04711484EFO_0007878, EFO_0007979
DiseaseER membrane protein complex subunit 4 measurement

CFB C2

5.16e-0471482EFO_0801580
DiseaseSpondylometaphyseal dysplasia

ACP5 TRPV4

5.16e-0471482cv:C4759767
DiseaseType II Collagenopathies

ACP5 TRPV4

5.16e-0471482cv:CN043672
Diseasemuscular atrophy (implicated_via_orthology)

CHUK MTOR

5.16e-0471482DOID:767 (implicated_via_orthology)
Diseaselifestyle measurement, anxiety disorder measurement

TTC27 TTC6 URB1 LRBA USH2A

6.52e-041371485EFO_0007795, EFO_0010724
Diseaseresponse to vitamin

P3H3 SLC6A1

6.86e-0481482GO_0033273
Diseaseretinal detachment, retinal break

DLG5 FAT3 RGL1

7.19e-04351483EFO_0005773, EFO_0010698
Diseasecomplement factor B measurement

CFB C2

8.79e-0491482EFO_0008096
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

ADGRV1 SCN9A

8.79e-0491482C3502809
Diseaseperiodontitis

CRACR2A FAT3 ITGA8 TTC6 FMNL3 UHRF2

9.41e-042231486EFO_0000649
Diseaseretinitis pigmentosa (is_implicated_in)

PRPF8 WDR19 USH2A

1.15e-03411483DOID:10584 (is_implicated_in)
DiseaseJeune thoracic dystrophy

IFT172 WDR19

1.33e-03111482C0265275
Diseasequality of life during menstruation measurement, acne

FMNL3 NLN

1.33e-03111482EFO_0003894, EFO_0009366
DiseaseMyoclonic Astatic Epilepsy

SLC6A1 SCN9A

1.33e-03111482C0393702
DiseaseBrugada Syndrome 1

SCN5A PKP2

1.88e-03131482C4551804
DiseaseHereditary Motor and Sensory-Neuropathy Type II

SCN9A TRPV4

1.88e-03131482C0270914
DiseaseRetinitis Pigmentosa

IFT172 CDHR1 PRPF8 USH2A

1.89e-031041484C0035334
Diseasewet macular degeneration

CFB C2

2.19e-03141482EFO_0004683
DiseaseN-acetylglycine measurement

GSTP1 UHRF2

2.19e-03141482EFO_0021002
Diseaseautosomal dominant polycystic kidney disease (is_marker_for)

ITGA8 CFB

2.19e-03141482DOID:898 (is_marker_for)
DiseasePeripheral Nervous System Diseases

SLC12A6 DPYD GSTP1

2.54e-03541483C4721453
Diseaseacute lymphoblastic leukemia (is_implicated_in)

DPYD CFB GSTP1

2.68e-03551483DOID:9952 (is_implicated_in)
Diseaseneutrophil collagenase measurement

CFB C2

2.86e-03161482EFO_0008248
DiseaseDrug-induced agranulocytosis

SLITRK1 SCN8A

2.86e-03161482HP_0012235
DiseaseVaricose veins

AGPAT5 DUSP8 CNTNAP1 ADGRV1 FMNL3

2.95e-031931485HP_0002619
DiseaseAge-related macular degeneration

CFB C2

3.63e-03181482cv:C0242383
DiseaseX-11470 measurement

TTC27 C2

4.04e-03191482EFO_0021241
Diseasediet measurement, HOMA-B

FAT3 DUSP16

4.04e-03191482EFO_0004469, EFO_0008111
Diseasepolycystic kidney disease (biomarker_via_orthology)

CFB MTOR

4.04e-03191482DOID:0080322 (biomarker_via_orthology)
DiseaseDisorder of eye

CDHR1 ADGRV1 PRPF8 GUCA1A USH2A

4.40e-032121485C0015397
Diseasememory performance

DPYD MYH11 SLC19A2 TSPAN19 PPP6R1 PRPF8 GSTP1

4.70e-034091487EFO_0004874
Diseaseschizophrenia (implicated_via_orthology)

SLC6A1 MTOR ELFN1

4.88e-03681483DOID:5419 (implicated_via_orthology)
Diseasecerebellar cortex volume measurement

LRRC4C TTC6

4.93e-03211482EFO_0010291
Diseaseeye colour measurement

LRRC4C NUDCD3 SV2B LRP2 USH2A

4.95e-032181485EFO_0009764
Diseasetestosterone measurement

CPPED1 SLC17A3 NAB1 TTC27 ZMIZ1 URB1 ATP6V0D1 ZFHX4 PGAP1 DUSP16 UGCG C2 PLCG1 USH2A

5.00e-03127514814EFO_0004908

Protein segments in the cluster

PeptideGeneStartEntry
QTAGYFLGNVLFLAL

SLC33A1

221

O00400
VAGALFNINFYAGAL

CXCR3

126

P49682
GFLDYILGNSSDAQL

AGBL3

376

Q8NEM8
ILYSLVNGNDGAFEI

CDHR1

281

Q96JP9
NFTLDGYVQRFILNG

CNTNAP1

276

P78357
IGYIEDGAFSGQFNL

ELFN1

96

P0C7U0
LPEGIFDTNYNLFNL

CPN2

376

P22792
RNALEIGFLVGQYFL

GJD2

206

Q9UKL4
AEGANAAYLQLLNLF

COPS7B

56

Q9H9Q2
LYSILSNLGDFQFLF

ATP13A3

956

Q9H7F0
NFNFLGQLLEYERSL

DUSP8

286

Q13202
IVATDLNEYGFLGLF

ABCA9

1151

Q8IUA7
ALNGDAFGVFVIYNI

ADGRV1

2571

Q8WXG9
YLIFAENVFLGDQNS

ADGRV1

3466

Q8WXG9
NFLADFYLVNGLVLE

ANKRD13C

356

Q8N6S4
QLYDGATALFLAAQG

ANKRD29

141

Q8N6D5
QILADQYGNAISLFG

ACACA

361

Q13085
LLFAYNGDVGLISIN

ANKEF1

236

Q9NU02
DAIFQGLTQDQGFYT

DPYD

291

Q12882
GLGEQLATENNLIFY

CRACR2A

671

Q9BSW2
AGLLYDFQLINVEDF

AQR

1171

O60306
FELLQQITYLDGFDQ

ANP32E

136

Q9BTT0
DVFGDISFLQGNYEL

CDC42EP3

51

Q9UKI2
QQLFSYAILGFALSE

ATP5MC3

111

P48201
KLGQVFFLSNDLDLY

ATP10B

391

O94823
LLGQGYCVFLDNFNI

PGBD4

321

Q96DM1
FLNVLNFGDQGVYDI

RFT1

266

Q96AA3
DTALQDYIEGGLINF

RGL1

431

Q9NZL6
VDFSLSGRLLFAGYN

GNB5

331

O14775
QLLDFLSGKQYAVGD

PARPBP

131

Q9NWS1
GLLYLNDDFQGGDLF

P3H3

611

Q8IVL6
LYALFQSAEAGIFVL

SLC10A4

366

Q96EP9
GGSFRLLQEGQALEY

CFB

46

P00751
AVNLLGLLFYLIFGE

SLC17A3

391

O00476
SNLGNAYIFLGEFET

GPSM2

246

P81274
FTLFLAYDTQLVLGN

TMBIM1

261

Q969X1
GDQALLGGIFYFLNI

MAEL

106

Q96JY0
YLLGNLAAADLFAGV

LPAR2

66

Q9HBW0
GQDAGYIFGLQSLID

IP6K2

401

Q9UHH9
GNVQDFLRVLFGFLY

NUDCD3

21

Q8IVD9
GANQLLELFDLFRYF

MDP1

76

Q86V88
FRNLSLEYLDLFGNT

LRR1

291

Q96L50
LASLEKLYIGQDQGF

LRRIQ4

371

A6NIV6
ANLLSYFDAFIQQGG

NAB1

21

Q13506
FVGTLQYLAPELFEN

CHUK

181

O15111
NQGILEFYGDDIALL

C2

551

P06681
GTNLYGAQTFFLCLE

MGAM

296

O43451
ELQLEYLLGAFESLG

ECPAS

1686

Q5VYK3
ELQYFLRAGTGLAAF

FAT2

1066

Q9NYQ8
GLFLQLYLNGTDVLF

OR51T1

201

Q8NGJ9
YFNVSLESGDLLVNG

PCDHGB1

71

Q9Y5G3
AGLEYGDQLLEFNGI

DLG5

1386

Q8TDM6
AYIGFIQSLAQFLGA

NCKAP1L

746

P55160
LNAAQIFAIYQLGLG

LRBA

371

P50851
GAFEGLSNLRYLNLA

LRRC4C

191

Q9HCJ2
NLTIDGYFYSLILEG

LRP2

3211

P98164
GIILLTFGFILDQNY

MS4A5

131

Q9H3V2
IFIYNLGQDADEGIL

ELAVL1

246

Q15717
LLYSFRLFGIQGEAQ

IGHV8-51-1

6

P0DTE2
GLFVAGINLTENLQY

PLCXD1

246

Q9NUJ7
TLLYFDSVLLAFGNL

GOLT1A

26

Q6ZVE7
QAGFSLDFYKNGDLI

ITGA8

201

P53708
GFLLLAGTQDGNIYQ

PAAF1

291

Q9BRP4
IFNAGELTLVEYGNN

IFT172

411

Q9UG01
DGESYLQLQDLLDGF

ITPKA

241

P23677
AYFLLAAFALQADLG

FRMD6

151

Q96NE9
LYSLYGISQNAGDFL

ACOX1

561

Q15067
DLDGNGLLSLEEYNF

EFCAB7

416

A8K855
GQDILVFYVNFGDLL

CENPC

886

Q03188
IQAYLDNVFDVGGLL

FMNL3

371

Q8IVF7
ISPNFNFLGQLLDYE

DUSP16

281

Q9BY84
LNLEDGFLDFYSINR

FAT3

706

Q8TDW7
GDQISFADYNLLDLL

GSTP1

146

P09211
DQAGGLIAFAQYIAE

UGCG

221

Q16739
GGVLFLVLNSQFYEN

CPPED1

156

Q9BRF8
GLLLGGYNEFLEHAQ

MDH1B

76

Q5I0G3
SGQLTLYEFRQFFGL

GUCA1A

31

P43080
TFLENLLRYGLFLGA

MANBAL

16

Q9NQG1
FGQSLELDGIIYLQA

DCK

166

P27707
INLLYGFFFASLQDD

CENPI

181

Q92674
DYLFSQGLQGLKLFI

CENPI

721

Q92674
GDFGLDVYLTQLIFG

SLC22A13

356

Q9Y226
SNGDIYLLENGLNLF

SEC24C

976

P53992
IVGNFLENYGEALAA

SLC12A6

796

Q9UHW9
NLGLLDFGAAYLFVI

SLC15A2

571

Q16348
FYGITSNLVLFLNGA

SLC15A4

51

Q8N697
LYAQGLLAIQFLEFF

SLC19A2

116

O60779
LLFNGCILFGIEFSY

SLC45A1

121

Q9Y2W3
LGDGALFYFGLNIET

DDB1

606

Q16531
LFYFGLNIETGLLSD

DDB1

611

Q16531
AAFEGLVNLRYLNLG

LRRC4B

201

Q9NT99
LLAAIQLFGANLDDY

MTOR

1096

P42345
LGALGIANSFLDEYL

MGST2

121

Q99735
LDYDFQSGQLLVGIL

SYT5

116

O00445
NIFSDGFLEYSGLNR

USH2A

4101

O75445
LAFNLEGYIFVFLND

SLC35D2

166

Q76EJ3
GYLFGENSDLNFLGN

RNF157

51

Q96PX1
LDAATQIFFSYGLGL

SLC6A1

286

P30531
EQDNDFLIYLVSFLG

SV2B

531

Q7L1I2
LLEVAFFLYNGVSLG

RHBDL3

171

P58872
VNLGGNEYLNLFLLG

SLC22A16

381

Q86VW1
FNLQALGTYFEGLLE

PML

841

P29590
QFYDLLNIFELNGLP

PPP5C

246

P53041
NLGLNAKGAILYAFE

MEP1A

86

Q16819
ESLNYALGAGDLFNV

PSMD1

76

Q99460
LYALNGVAFELDLQQ

RUFY4

151

Q6ZNE9
NFDNVGAGYLALLQV

SCN5A

1401

Q14524
KVNFDNVGLGYLSLL

SCN9A

1386

Q15858
YNIFLLLEVGTFNAL

STRIP1

171

Q5VSL9
GASEFLPIYLENQFI

SLCO6A1

401

Q86UG4
NYFGAESLFNKLVEL

SECISBP2L

796

Q93073
VNFNEELVALYGGSL

PGAP1

126

Q75T13
FLQLGDYGSAIQFLV

WDR19

961

Q8NEZ3
LAFDLEGYAFILIND

SLC35D1

181

Q9NTN3
GYLFALLLDGDFTLA

SLC10A5

221

Q5PT55
GYFITQDSAFGNLIL

INIP

81

Q9NRY2
QAYVQFALSFLIAGD

URB1

196

O60287
AYLLGLLNSAGNEFT

ACTL7A

251

Q9Y615
ALGLFIYQSLDAIDG

CHPT1

101

Q8WUD6
RSDLLLEGFNNYTFL

MYH11

296

P35749
EGLLNTYQELLGLSF

NLN

391

Q9BYT8
GVLYNQFLSQVDFEL

GTF2H4

406

Q92759
GDFYLQLIEGLDILF

RNF17

691

Q9BXT8
LGNVDAFQLADGLQY

PRPF8

566

Q6P2Q9
QLENGYTLFDYDVGL

UHRF2

51

Q96PU4
ALLENFGFELVIQYN

ZFHX4

1866

Q86UP3
GALFLFLSANALGNY

ZDHHC22

51

Q8N966
LLAGALTELGYNVFF

TMEM60

116

Q9H2L4
FLLAFLSYNRSLDQG

TMTC1

176

Q8IUR5
QYGFALEDFKQAALI

TTC6

191

Q86TZ1
LGTLENGNLDLYFVD

TDRKH

376

Q9Y2W6
FLGLDDLEYLQADFN

SLITRK1

126

Q96PX8
ATQLFNLLSGEGYLE

TMC4

221

Q7Z404
FLLIEDQGAQGYELF

VAV1

471

P15498
LPEFQQFLLDYQGEL

PLCG1

251

P19174
ILSLGDNFYFTGVQD

ACP5

66

P13686
FDNVGAGYLALLQVA

SCN8A

1396

Q9UQD0
YAQLGFLVFGSQVDD

PKD2L2

421

Q9NZM6
LGADESLLNRLYGFL

PPP6R1

96

Q9UPN7
AAGYFQNLFLNTGLD

ZBTB39

51

O15060
LASFGNDDILNLARY

ZNF862

961

O60290
QIQNDYLFQLGFGEL

PHLPP1

491

O60346
FLGGLDALYSLRLDQ

SEMA3G

71

Q9NS98
DFGDLLIYSGALLVF

TMEM238

66

C9JI98
QSLGQGLEFLIYFQG

TRBV7-2

56

A0A1B0GXF2
FENYTGVQILLYGDL

AGPAT5

66

Q9NUQ2
SGSFLQLLLEGNYEA

TTC27

31

Q6P3X3
FLANLLGASVQEYFV

TOPBP1

666

Q92547
KYFLNLINGAFLVLG

TSPAN19

11

P0C672
ANGLLDFDIFYNVTG

PKP2

546

Q99959
NSLFIDGSFQLLYFI

TRPV4

541

Q9HBA0
QQGFDLDLGYRLLAV

ZMIZ1

66

Q9ULJ6
FGKYNFLLQEDGDLA

ZC3H7B

946

Q9UGR2
ELYFNVDNGYLEGLV

ATP6V0D1

6

P61421
FQNYFADGVLSLGEL

NECAB3

61

Q96P71