Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionoligosaccharide binding

SELP ITLN1

3.30e-0420272GO:0070492
GeneOntologyCellularComponentbrush border membrane

SLC34A2 ITLN1 SLC6A14

1.47e-0483263GO:0031526
GeneOntologyCellularComponentcluster of actin-based cell projections

CEACAM16 SLC34A2 ITLN1 SLC6A14

1.57e-04223264GO:0098862
GeneOntologyCellularComponentbrush border

SLC34A2 ITLN1 SLC6A14

8.67e-04152263GO:0005903
DomainSushi

SELP CFH PAPPA CR2

7.63e-0752264PF00084
DomainCCP

SELP CFH PAPPA CR2

8.90e-0754264SM00032
DomainSUSHI

SELP CFH PAPPA CR2

1.03e-0656264PS50923
DomainSushi_SCR_CCP_dom

SELP CFH PAPPA CR2

1.11e-0657264IPR000436
DomainKeratin_B2_2

KRTAP9-7 KRTAP9-8

1.34e-0339262PF13885
DomainKAP

KRTAP9-7 KRTAP9-8

2.94e-0358262IPR002494
PathwayWP_EXTRAFOLLICULAR_AND_FOLLICULAR_B_CELL_ACTIVATION_BY_SARSCOV2

CR2 PTCRA EBI3

1.73e-0474213M45517
PathwayWP_COMPLEMENT_SYSTEM

SELP CFH CR2

3.72e-0496213M39581
PathwayREACTOME_SLC_TRANSPORTER_DISORDERS

SEH1L SLC34A2 SLC6A14

4.08e-0499213M27474
Pubmed

Targeted inhibition of the complement alternative pathway with complement receptor 2 and factor H attenuates collagen antibody-induced arthritis in mice.

CFH CR2

1.74e-06327219828624
Pubmed

A complement receptor locus: genes encoding C3b/C4b receptor and C3d/Epstein-Barr virus receptor map to 1q32.

CFH CR2

1.74e-0632723782802
Pubmed

Molecular cloning of rat and mouse membrane cofactor protein (MCP, CD46): preferential expression in testis and close linkage between the mouse Mcp and Cr2 genes on distal chromosome 1.

CFH CR2

5.80e-0652729799332
Pubmed

Complement-dependent P-selectin expression and injury following ischemic stroke.

SELP CR2

5.80e-06527217082645
Pubmed

Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation.

CFH CR2

5.80e-06527220962256
Pubmed

Genetic organization of complement receptor-related genes in the mouse.

CFH CR2

1.62e-0582722564419
Pubmed

An ultra-high sulfur keratin gene is expressed specifically during hair growth.

KRTAP9-7 KRTAP9-8

1.62e-0582722465353
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

SELP CR2 ITLN1

6.61e-0510127323382219
Pubmed

Aurora B opposes PP1 function in mitosis by phosphorylating the conserved PP1-binding RVxF motif in PP1 regulatory proteins.

SEH1L RIF1

6.92e-051627229764992
Pubmed

Genetic influences on the end-stage effector phase of arthritis.

SELP CFH

6.92e-051627211489951
Pubmed

Genetic contributions of nonautoimmune SWR mice toward lupus nephritis.

CFH CR2

1.59e-042427211739537
Pubmed

Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium.

KRTAP9-7 KRTAP9-8

1.86e-042627215454262
Pubmed

Risk of non-Hodgkin lymphoma in association with germline variation in complement genes.

CFH CR2

2.66e-043127219344414
Pubmed

Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21.

KRTAP9-7 KRTAP9-8

3.80e-043727211279113
Pubmed

Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense.

SLC34A2 SLC6A14

5.88e-044627219190083
Pubmed

Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins.

SH3TC2 SGSM1

7.23e-045127211853319
Cytoband1q32

CFH CR2

3.85e-04492721q32
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

SELP CFH PAPPA CR2

4.14e-07572041179
GeneFamilyComplement system|Sushi domain containing

CFH CR2

7.16e-0436202492
GeneFamilyKeratin associated proteins

KRTAP9-7 KRTAP9-8

6.37e-03109202619
GeneFamilyAdenosine receptors|V-set domain containing

CEACAM16 TREML4

1.38e-02163202590
CoexpressionGSE45365_WT_VS_IFNAR_KO_BCELL_MCMV_INFECTION_DN

ESCO2 SELP CFH HIVEP3 TROAP

1.57e-06196275M9989
CoexpressionGSE25088_WT_VS_STAT6_KO_MACROPHAGE_IL4_STIM_DN

SELP ERI2 CR2 TROAP

4.93e-05199274M8029
CoexpressionGSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_UP

CFH SEH1L ERI2 PTCRA

4.93e-05199274M3439
CoexpressionSENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP

ESCO2 CFH SEH1L PAPPA RIF1

5.18e-05404275M19488
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Tall_Cell|TCGA-Thryoid / Sample_Type by Project: Shred V9

SLC34A2 SH3TC2 EBI3 SLC6A14

3.46e-061732742e9dc137f3675eee07f941eb4cfcaf24a83ab0fb
ToppCellIPF-Epithelial-Mesothelial|IPF / Disease state, Lineage and Cell class

CFH PAPPA SH3TC2 ITLN1

4.05e-061802741fa54bf4dba72866b2295639d991af639341bc08
ToppCellPBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_1|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SELP SH3TC2 AGBL5 PTCRA

4.05e-061802743c605d6adb4199963532f3639f2c768f7e575152
ToppCellPBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_1|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SELP SH3TC2 AGBL5 PTCRA

4.05e-061802743d52ca0568f9c0d6359b302ff5ff41b075f78597
ToppCellIPF-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

CFH PAPPA SH3TC2 ITLN1

4.32e-061832747df20e3172a1220ff427f30181f4f0c3b7fe2d42
ToppCellASK428-Epithelial-Transformed_epithelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

CFH PAPPA SH3TC2 ITLN1

4.91e-0618927487189275234b5d59484c58acbb14a09903f2b578
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|356C / Donor, Lineage, Cell class and subclass (all cells)

ESCO2 PTCRA TROAP ITLN1

5.12e-06191274a2c235a55094e4fd5273d764c9e2967116b48c23
ToppCell(3)_Macrophage_Dividing|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

ESCO2 ERI2 TROAP ITLN1

5.12e-06191274b42f0b89bb94fd43786ff50f1caeb3ebfbbb43fd
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFH SLC34A2 PAPPA ITLN1

5.55e-061952748a9d05f7a5397836b7dfb8ae4f7c4896042ac0fe
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFH SLC34A2 PAPPA ITLN1

5.67e-06196274147dc1ca5942df48a083cce39a9a7541430f8365
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Papillary_Muscle_Invasive_Urothelial_Carcinoma-10|TCGA-Bladder / Sample_Type by Project: Shred V9

KRTAP9-7 PAPPA KRTAP9-8

6.40e-051292736a201c6344a015e5cf2f79ccf397fd7ad66b6768
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ESCO2 PTCRA TROAP

8.52e-051422737bd05d0c0ac2dee0e6cc0f3c531f9154bf300c75
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ESCO2 PTCRA TROAP

8.52e-0514227392bf826827b3e3387ad326566556fc90c5c2f4d5
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P4|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ESCO2 PTCRA TROAP

8.52e-05142273328d08ba2712cd42bb9846ac4d7453ae165b75e2
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ESCO2 PTCRA TROAP

8.52e-0514227394774d3e598d074f48146b0b094705dc48af5a1f
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-6|TCGA-Skin / Sample_Type by Project: Shred V9

KRTAP9-7 P2RY4 KRTAP9-8

9.25e-05146273522c32103c24fc26836bb5b642083904682d9292
ToppCellPCW_05-06-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte2_(17)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SELP SH3TC2 PTCRA

1.00e-041502736d65df8c0937b498585d1e79919ec73daa354e21
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SELP PAPPA SH3TC2

1.06e-0415327365641cc82883716dba0fefb749a30174a63f4da5
ToppCell390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

AGBL5 EBI3 TROAP

1.19e-041592730fbfdb18b7ed4bde077add13f2b3636e144b254f
ToppCellPBMC-Mild-Hematopoietic-Platelet-Platelet-plt_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SELP SH3TC2 PTCRA

1.24e-04161273bfb79277889142133ce86492a808f3083a7547e8
ToppCellPBMC-Mild-Hematopoietic-Platelet-Platelet-plt_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SELP SH3TC2 PTCRA

1.24e-04161273d6f4b0e4e3b2a4e6232a6de3d67b210e24f8c89d
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ESCO2 SH3TC2 TROAP

1.24e-041612732165897924c790fec43502283f1df221c56c1e9f
ToppCellfacs-Lung-Endomucin-24m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEACAM16 TREML4 ITLN1

1.28e-0416327304152557aae230e9587fcc16cbabf1247cc5b419
ToppCellfacs-Lung-Endomucin-24m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEACAM16 TREML4 ITLN1

1.28e-041632730644eb8a66d4e944063125c423de66d2393388b1
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 CEACAM16 EBI3

1.33e-04165273953c8242a81a39ade63ac8e5b34fe58575771746
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte2_(17)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SELP SH3TC2 PTCRA

1.33e-04165273d2ab667ff53f538b12ee4e07ea4b4d118600a228
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 SH3TC2 TROAP

1.33e-04165273eec2d327c94832d1390314c93ef6a2be4648478b
ToppCellnormal_Pleural_Fluid-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

ERI2 SLC6A14 CAPN15

1.35e-04166273d16af6570806ed2880bd0efb5298932fd2a89cf5
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 SH3TC2 TROAP

1.38e-0416727350c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 SH3TC2 TROAP

1.40e-04168273d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCellmetastatic_Brain-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

SGSM1 PTCRA CAPN15

1.40e-041682734bf3f85aac4b335efa93d22c9ce7b153cb5ce152
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 SH3TC2 TROAP

1.43e-04169273b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ESCO2 ERI2 TROAP

1.43e-04169273e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCellwk_15-18-Hematologic-Meg-ery-Megakaryocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SELP SH3TC2 PTCRA

1.43e-04169273d571e84e01e3316748d4407ed98881b17484e035
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 SH3TC2 TROAP

1.45e-0417027321bfe070e63722672176052b386167ea4c3dc4e5
ToppCellwk_20-22-Hematologic-Meg-ery-Megakaryocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SELP SH3TC2 PTCRA

1.45e-04170273eace4dd09cdbde0fa40a6aa0f3dba1114d0ce475
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

ESCO2 ERI2 TROAP

1.45e-041702735319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ESCO2 EBI3 TROAP

1.48e-0417127341932c9e70829ee3d55ca5fdb74d290fc8229416
ToppCellCOVID-19-lung-RBC|lung / Disease (COVID-19 only), tissue and cell type

SELP SH3TC2 PTCRA

1.48e-041712730e8d63c8fbccdda4f1ef00de00667a50464b104b
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

ESCO2 TROAP SLC6A14

1.48e-041712734ede6e916e593f208f2f8ccf82ef2335e061fc86
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 CEACAM16 EBI3

1.48e-04171273bf475a69db04d4a886e442704955c6a96ff0de46
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 RIF1 TROAP

1.50e-041722732b6cd84c946b1e800caba452ae70145ea285fec1
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 ERI2 TROAP

1.50e-041722731171e754fd503a0c1152162fcc12a115088a08c7
ToppCell5'-Adult-LargeIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CR2 EBI3 TROAP

1.53e-04173273b7e0193fd4983cb38d1bee441f608f73ee8743b9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 SH3TC2 TROAP

1.55e-0417427384da9faff088d05233183b425385beb054c92d1b
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Myeloid-new-cluster|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC34A2 TREML4 TROAP

1.55e-04174273718e14d9a4264456459bec4c062c94c3a848d43a
ToppCellASK428-Immune-B_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

ESCO2 SEH1L PTCRA

1.55e-04174273b5a7a612a515736cf3489afd0f6ad2054d54526f
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ESCO2 TROAP SLC6A14

1.58e-041752730b1aaa028ba844d4bcb4509fdab8bee648373935
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

ESCO2 TROAP SLC6A14

1.58e-04175273fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Myeloid-macrophage|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC34A2 TREML4 TROAP

1.58e-0417527361fdafba120fbda063d4dc05263d6f8d1dcab1e1
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

ESCO2 TROAP SLC6A14

1.58e-0417527336c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Myeloid|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC34A2 TREML4 TROAP

1.58e-041752738de8031fdf2af187642833feb80caa64932897cf
ToppCellnormal_Lung-Fibroblasts-Mesothelial_cells|normal_Lung / Location, Cell class and cell subclass

CFH PAPPA ITLN1

1.61e-04176273f31d7234053085a82cf9d55aeedd1e04d34789c3
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ESCO2 ERI2 TROAP

1.61e-041762738813c01ea080f373fe3970c5e1ba4c2dca0f7f02
ToppCellfacs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESCO2 ERI2 TROAP

1.63e-04177273e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCell356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CFH EBI3 ITLN1

1.63e-04177273709235694cc711b9b79690e23c94577b2ae06811
ToppCellfacs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESCO2 ERI2 TROAP

1.63e-041772738a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCell368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ESCO2 ERI2 TROAP

1.63e-04177273844017225e9039d1bc621a9630a30c2e9a51b36d
ToppCell356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CFH EBI3 ITLN1

1.63e-041772737f9c2a45a994b32f15e5693f7cb873716a4eb568
ToppCell368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ESCO2 ERI2 TROAP

1.63e-0417727326c25d10aa511b64cc7db43a8deea7b5d31bca96
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CEACAM16 HIVEP3 SLC34A2

1.66e-04178273a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ESCO2 ERI2 TROAP

1.72e-04180273334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SELP CFH ITLN1

1.72e-041802735861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ESCO2 ERI2 TROAP

1.77e-04182273336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell3'_v3-bone_marrow-Hematopoietic_Erythro-Mega-Megakaryocyte_early|bone_marrow / Manually curated celltypes from each tissue

SELP SH3TC2 PTCRA

1.77e-041822731a755ea44daf8447a3a1c30de7fdb9c3888bcbde
ToppCellremission-Platelet|remission / disease stage, cell group and cell class

SELP SH3TC2 PTCRA

1.77e-0418227365e2798aacd670cbc3a8c8e9d1a2f7768513bb70
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 ERI2 TROAP

1.83e-04184273d1e0e3b0eed2db8a5b7e3d6f81294667e4ba64e5
ToppCellcontrol-Others-Megakaryocytes|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SELP SH3TC2 PTCRA

1.83e-04184273213915f2889ce8ecbe5f7b19bc2b24ed8c5efe1d
ToppCelltumor_Lung-Fibroblasts-Mesothelial_cells|tumor_Lung / Location, Cell class and cell subclass

CFH PAPPA ITLN1

1.83e-04184273b0a251030d127858e68cf164be158f209a4d720f
ToppCellcontrol-Others|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SELP SH3TC2 PTCRA

1.83e-04184273a63b39fcc570b554cf10e8e47c2c1e079034768f
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

ESCO2 CR2 TROAP

1.86e-041852739766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CFH SH3TC2 ITLN1

1.86e-04185273492529121cb9e88bd3c0db6b54af3cd2979572bc
ToppCellDividing_Macrophages-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ESCO2 TROAP ITLN1

1.89e-041862730067eb78d4c7e32b9563550d9fcaf13445ee6a48
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFH PAPPA ITLN1

1.89e-041862737812ed80d2378aca9957ef22fc3c8fb7fb58434b
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SLC34A2 PAPPA ITLN1

1.92e-041872738e8f1f2a78ac5f13a414fd448af7d7ff1ea86f0f
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CFH ITLN1 SLC6A14

1.95e-0418827307705bed928683470a52c8ccfa40ffb9a0971318
ToppCell367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ESCO2 ERI2 TROAP

1.95e-04188273f5102e8d95506c25c675094b86162a6a50087b64
ToppCellHealthy/Control-Platelet|World / Disease group and Cell class

SELP SH3TC2 PTCRA

1.95e-04188273552077e4597d0956f4d8c40c9de8f109e87cb857
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ESCO2 ERI2 TROAP

1.95e-0418827395d0a796d62ce6d121e2028c378faffc14b35275
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH PAPPA ITLN1

1.95e-04188273e82104f71bcdab7392fdb076dc3560255964fd9e
ToppCellHealthy/Control-Platelet|Healthy/Control / Disease group and Cell class

SELP SH3TC2 PTCRA

1.98e-041892733de7f8d8b8451ed9a146cce499552e9a060e9099
ToppCell3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SELP CFH ITLN1

2.01e-0419027392fdfed12061ee9f6c7171cf8a7f3344921f2d40
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-B|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TREML4 PTCRA EBI3

2.04e-04191273a4200717672e2358eb649eae2553f293b4fd8f7e
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFH HIVEP3 PAPPA

2.04e-0419127308720998aa55131d7377c4c67c4c935865bd7d79
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SLC34A2 PAPPA ITLN1

2.04e-041912734c4eb61e6179d2f8fc524d2f813db9cba84f67a2
ToppCellControl-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

SELP CFH SH3TC2

2.08e-041922737e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIAA0408 SLC34A2 SLC6A14

2.11e-04193273136775166ecc38399091f262279180dbe5a1dcd7
ToppCellsevere_COVID-19|World / disease group, cell group and cell class (v2)

SELP TREML4 PTCRA

2.11e-041932739012cadd138be775fb167a5bc895e512619f8a95
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibro-meso|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH PAPPA ITLN1

2.14e-04194273f4286ae7bb8350c42d50727ee8688b80129714f6
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH PAPPA ITLN1

2.14e-0419427379baee8b35b7707bbeb07c73b5e17b68bcd7bbc2
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibro-meso|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH PAPPA ITLN1

2.14e-04194273f6e348f1f35c526cad6c349f1fdd0bd92d18aa3c
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH PAPPA ITLN1

2.14e-0419427387461bd6d7f702c0a0f5e0c8ace3049125a51f9a
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH PAPPA ITLN1

2.14e-04194273c578cf7c6b4d6f31f87dde8845de5b3891f16822
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH PAPPA ITLN1

2.14e-04194273421344cc4b601d9745fa72d0af3124dab11d1d27
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Polychromatic_Erythroblast|World / Lineage, cell class and subclass

ESCO2 ERI2 TROAP

2.14e-04194273008bb0072f414a48d052429101bdc990ee4f80c2
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|367C / Donor, Lineage, Cell class and subclass (all cells)

ESCO2 TROAP ITLN1

2.14e-04194273a12b64945e10f00aa983678a02586c59badc1570
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH PAPPA ITLN1

2.14e-04194273ce599ed0dc181aea0584e426636de5098f34ebe6
ToppCell(7)_Epithelial-J_(AT1-AT2_progenitors)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

ESCO2 SLC34A2 TROAP

2.17e-0419527370e6b58c502a2abeb4e36bed179020c675468bd4
ToppCellParenchymal-NucSeq-Stromal-Mesofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFH PAPPA ITLN1

2.17e-04195273a52685f76eca269a7d2de8dfc317439483e233fa
ToppCellASK428-Epithelial-Transformed_epithelium|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CFH PAPPA ITLN1

2.17e-04195273c750602c765a51075ba6ede78e3ba80b62374481
ComputationalGenes in the cancer module 58.

CFH CR2

3.26e-0421142MODULE_58
ComputationalComplement.

CFH CR2

3.92e-0423142MODULE_130
ComputationalGenes in the cancer module 119.

SELP CR2 PTCRA

7.54e-04143143MODULE_119
ComputationalNeighborhood of IGFBP1

PAPPA EBI3

9.15e-0435142GNF2_IGFBP1
ComputationalNeighborhood of MMP11

PAPPA EBI3

1.32e-0342142GNF2_MMP11
ComputationalNeighborhood of TIMP2

PAPPA EBI3

1.58e-0346142GNF2_TIMP2
ComputationalNeighborhood of KISS1

PAPPA EBI3

1.79e-0349142GNF2_KISS1
DrugKetoconazole [65277-42-1]; Up 200; 7.6uM; PC3; HT_HG-U133A

SELP PAPPA RIF1 EBI3

5.62e-051942544624_UP
DrugCimetidine [51481-61-9]; Up 200; 15.8uM; PC3; HT_HG-U133A

RIF1 PTCRA EBI3 P2RY4

5.73e-051952544063_UP
DrugEvoxine [522-11-2]; Up 200; 11.6uM; PC3; HT_HG-U133A

SELP CFH PTCRA P2RY4

5.96e-051972543681_UP
DrugArcaine sulfate [14923-17-2]; Up 200; 14.8uM; HL60; HT_HG-U133A

SELP SLC34A2 RIF1 PTCRA

6.08e-051982543010_UP
DrugKetoprofen [22071-15-4]; Up 200; 15.8uM; MCF7; HT_HG-U133A

HIVEP3 PAPPA RIF1 PTCRA

6.08e-051982544751_UP
DrugImipenem [74431-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A

HIVEP3 PTCRA EBI3 P2RY4

6.20e-051992545997_UP
Diseasemediator of RNA polymerase II transcription subunit 1 measurement

CFH PTCRA

8.70e-066232EFO_0008228
DiseaseT-cell surface glycoprotein CD3 epsilon chain measurement

SELP CFH

4.51e-0513232EFO_0802114
DiseaseSLAM family member 7 measurement

CFH ITLN1

7.85e-0517232EFO_0008287
Diseasehuman immunodeficiency virus infectious disease (is_marker_for)

SELP CR2

3.60e-0436232DOID:526 (is_marker_for)
Diseaseairway imaging measurement

HIVEP3 SEH1L

4.02e-0438232EFO_0007627
Diseasecomplement factor H measurement

CFH HIVEP3

4.68e-0441232EFO_0008097

Protein segments in the cluster

PeptideGeneStartEntry
SPISCSLSDSPSWNC

AGBL5

846

Q8NDL9
KPTSSDCSPVRSSSW

ERI2

556

A8K979
TSLTLWCVSRSCPEP

CEACAM16

246

Q2WEN9
TAKCTSTGWIPAPRC

CFH

306

P08603
PSSPDFTTWSCAKCT

CAPN15

336

O75808
FTTWSCAKCTLRNPT

CAPN15

341

O75808
SSYPTCPAQAWCSRS

PTCRA

241

Q6ISU1
FKEWTCSSSPSLPRS

ITLN1

26

Q8WWA0
RSPSTSWFQKTCSTP

KIAA0408

371

Q6ZU52
QPCKSSVRTWSPNSA

PAPPA

751

Q13219
CSPCTTIKATPWNQS

MAGEA13P

71

A6NCF6
CRWAATPQDSSCSTP

P2RY4

346

P51582
NCLSSGKWSAVPPTC

CR2

196

P20023
SWPCLQQTPTSTSCT

EBI3

76

Q14213
ESPSSTECPRAWQCS

ESCO2

511

Q56NI9
CTTSGRWSATPPTCK

SELP

616

P16109
PTCCRTTCWKPTTVT

KRTAP9-7

11

A8MTY7
PTCCRTTCWKPTTVT

KRTAP9-8

11

Q9BYQ0
CKLSCSCISWNPSSS

SEH1L

161

Q96EE3
QTRCVWSPLASPSTS

RIF1

2166

Q5UIP0
CQSPLWHSRPSGCSS

SH3TC2

1261

Q8TF17
VPSTANCTSPSLCWT

SLC34A2

316

O95436
PKSWCQQTSPSRCTL

TREML4

51

Q6UXN2
CASPWQKAESRSPSC

HIVEP3

2131

Q5T1R4
SSLPPCCSQWAPATT

TROAP

656

Q12815
LWQPSPRKSSCSSCS

SGSM1

501

Q2NKQ1
SAKFPNGSPSSWCCS

USP3

16

Q9Y6I4
CSSWSDKNCSRSPIV

SLC6A14

156

Q9UN76