Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	HOXB3 HHEX GSX1 KMT2D HIVEP1 ERFL NFE2 SOX30 ZBTB22 SKOR1 SHOX MECOM DMRTB1 EVX1 NR5A1 TBX20 LYL1 BHLHE40 GLIS1 NOTCH1 NPAS1 PRDM1 TBX6	5.13e-09	1412	81	23	GO:0000981
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	HOXB3 HHEX GSX1 HIVEP1 SLC2A4RG NFE2 SOX30 ZBTB22 SKOR1 MECOM DMRTB1 ZNF683 EVX1 NR5A1 TBX20 LYL1 BHLHE40 GLIS1 NOTCH1 PRDM1 TBX6	2.21e-08	1271	81	21	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HOXB3 HHEX GSX1 HIVEP1 SLC2A4RG NFE2 SOX30 ZBTB22 SKOR1 MECOM DMRTB1 ZNF683 EVX1 NR5A1 TBX20 LYL1 BHLHE40 GLIS1 PRDM1 TBX6	8.11e-08	1244	81	20	GO:0000978
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	HOXB3 HHEX GSX1 HIVEP1 SLC2A4RG NFE2 SOX30 ZBTB22 SKOR1 MECOM DMRTB1 ZNF683 EVX1 NR5A1 TBX20 LYL1 BHLHE40 GLIS1 NPAS1 PRDM1 TBX6	2.31e-07	1459	81	21	GO:0000977
GeneOntologyMolecularFunction	transcription factor binding	ZNF703 SETD1A NCOR2 HHEX LATS1 PPRC1 TLE4 NR5A1 ZFPM1 TBX20 BHLHE40 TBX6	4.92e-05	753	81	12	GO:0008134
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	HOXB3 HHEX GSX1 KMT2D SOX30 SHOX MECOM TBX20 GLIS1 NOTCH1	8.73e-05	560	81	10	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	HOXB3 HHEX GSX1 KMT2D SOX30 SHOX MECOM TBX20 GLIS1 NOTCH1	9.53e-05	566	81	10	GO:0001216
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	ZNF703 SETD1A NCOR2 HHEX LATS1 TLE4 ZFPM1 TBX20 BHLHE40 TBX6	1.20e-04	582	81	10	GO:0140297
GeneOntologyMolecularFunction	transcription coregulator activity	NCOR2 KMT2D ATN1 PPRC1 TLE4 ZFPM1 RERE DCC NOTCH1	4.48e-04	562	81	9	GO:0003712
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	SETD1A KMT2D	4.48e-04	8	81	2	GO:0140945
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	SETD1A KMT2D	7.16e-04	10	81	2	GO:0140999
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	SRRT NCOR2 IGF2BP2 KMT2D ATN1 MAVS PPRC1 TLE4 FBXO7 ZFPM1 RERE DCC NOTCH1	7.53e-04	1160	81	13	GO:0030674
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	SETD1A KMT2D MECOM	7.55e-04	44	81	3	GO:0140938
GeneOntologyMolecularFunction	molecular adaptor activity	SRRT NCOR2 IGF2BP2 KMT2D ATN1 MAVS PPRC1 TLE4 FBXO7 OTUD4 ZFPM1 RERE DCC NOTCH1	1.03e-03	1356	81	14	GO:0060090
GeneOntologyMolecularFunction	transcription coactivator activity	KMT2D ATN1 PPRC1 RERE DCC NOTCH1	1.45e-03	303	81	6	GO:0003713
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	SETD1A NCOR2 LATS1 ZFPM1 TBX20 BHLHE40 TBX6	1.52e-03	417	81	7	GO:0061629
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	HHEX HIVEP1 SOX30 BHLHE40 GLIS1 PRDM1	1.91e-03	320	81	6	GO:0001227
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	HHEX HIVEP1 SOX30 BHLHE40 GLIS1 PRDM1	2.10e-03	326	81	6	GO:0001217
GeneOntologyMolecularFunction	transcription corepressor activity	NCOR2 ATN1 TLE4 ZFPM1 RERE	2.40e-03	229	81	5	GO:0003714
GeneOntologyMolecularFunction	protein-lysine N-methyltransferase activity	SETD1A KMT2D MECOM	2.67e-03	68	81	3	GO:0016279
GeneOntologyMolecularFunction	lysine N-methyltransferase activity	SETD1A KMT2D MECOM	2.78e-03	69	81	3	GO:0016278
GeneOntologyMolecularFunction	protein domain specific binding	HHEX HIVEP1 KIDINS220 ATN1 MAVS NFE2 PKD1 ADGRB1 SRP68 BHLHE40	2.79e-03	875	81	10	GO:0019904
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	SETD1A KMT2D	2.94e-03	20	81	2	GO:0042800
GeneOntologyMolecularFunction	chromatin binding	NCOR2 HHEX TLE4 ZNF683 NR5A1 RERE NOTCH1 BAHCC1 PRDM1	3.00e-03	739	81	9	GO:0003682
GeneOntologyMolecularFunction	histone methyltransferase activity	SETD1A KMT2D MECOM	3.01e-03	71	81	3	GO:0042054
GeneOntologyMolecularFunction	HMG box domain binding	HHEX HIVEP1	3.89e-03	23	81	2	GO:0071837
GeneOntologyMolecularFunction	Notch binding	NCOR2 NOTCH1	5.34e-03	27	81	2	GO:0005112
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	HOXB3 HHEX GSX1 KMT2D HIVEP1 MAVS PPRC1 SOX30 PKD1 SHOX MECOM EVX1 NR5A1 ZFPM1 TBX20 CCNK GLIS1 NOTCH1 TBX6	1.62e-06	1390	82	19	GO:0045944
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	ZNF703 NCOR2 HOXB3 HHEX HIVEP1 ATN1 TLE4 SOX30 SKOR1 MECOM ZFPM1 RERE TBX20 BHLHE40 GLIS1 NOTCH1 NPAS1 PRDM1 TBX6	1.79e-06	1399	82	19	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	ZNF703 NCOR2 HOXB3 HHEX HIVEP1 ATN1 TLE4 SOX30 SKOR1 MECOM ZFPM1 RERE TBX20 BHLHE40 GLIS1 NOTCH1 NPAS1 PRDM1 TBX6	2.07e-06	1413	82	19	GO:1902679
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	NCOR2 HOXB3 HHEX HIVEP1 ATN1 TLE4 SOX30 SKOR1 ZFPM1 TBX20 BHLHE40 GLIS1 NOTCH1 NPAS1 PRDM1 TBX6	3.29e-06	1053	82	16	GO:0000122
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	NCOR2 HOXB3 HHEX KMT2D LATS1 KIDINS220 LATS2 NFE2 PKD1 MECOM EVX1 CCNK NOTCH1 PRDM1 TBX6	3.36e-06	929	82	15	GO:0009792
GeneOntologyBiologicalProcess	in utero embryonic development	NCOR2 HHEX KMT2D LATS1 KIDINS220 LATS2 NFE2 PKD1 MECOM CCNK NOTCH1 PRDM1	3.97e-06	596	82	12	GO:0001701
GeneOntologyBiologicalProcess	negative regulation of cyclin-dependent protein serine/threonine kinase activity	HHEX LATS1 LATS2 FBXO7	5.11e-06	29	82	4	GO:0045736
GeneOntologyBiologicalProcess	negative regulation of cyclin-dependent protein kinase activity	HHEX LATS1 LATS2 FBXO7	5.88e-06	30	82	4	GO:1904030
GeneOntologyBiologicalProcess	cell fate commitment	GSX1 LATS1 LATS2 ZFPM1 TBX20 GLIS1 NOTCH1 PRDM1 TBX6	7.85e-06	338	82	9	GO:0045165
GeneOntologyBiologicalProcess	chordate embryonic development	NCOR2 HOXB3 HHEX KMT2D LATS1 KIDINS220 LATS2 NFE2 PKD1 MECOM CCNK NOTCH1 PRDM1 TBX6	1.22e-05	906	82	14	GO:0043009
GeneOntologyBiologicalProcess	regulation of extrathymic T cell differentiation	ZNF683 PRDM1	1.56e-05	2	82	2	GO:0033082
GeneOntologyBiologicalProcess	heart valve formation	ZFPM1 TBX20 NOTCH1	3.96e-05	17	82	3	GO:0003188
GeneOntologyBiologicalProcess	regulation of cyclin-dependent protein serine/threonine kinase activity	HHEX LATS1 LATS2 FBXO7 CCNK	4.04e-05	96	82	5	GO:0000079
GeneOntologyBiologicalProcess	embryo development	NCOR2 HOXB3 HHEX KMT2D LATS1 KIDINS220 LATS2 NFE2 PKD1 MECOM EVX1 ZFPM1 TBX20 CCNK NOTCH1 PRDM1 TBX6	4.13e-05	1437	82	17	GO:0009790
GeneOntologyBiologicalProcess	inner cell mass cell fate commitment	LATS1 LATS2	4.67e-05	3	82	2	GO:0001827
GeneOntologyBiologicalProcess	inner cell mass cellular morphogenesis	LATS1 LATS2	4.67e-05	3	82	2	GO:0001828
GeneOntologyBiologicalProcess	regulation of cyclin-dependent protein kinase activity	HHEX LATS1 LATS2 FBXO7 CCNK	4.92e-05	100	82	5	GO:1904029
GeneOntologyBiologicalProcess	regulation of Wnt signaling pathway	ZNF703 HHEX LATS1 LATS2 TLE4 SOX30 NOTCH1 WNK2	1.07e-04	368	82	8	GO:0030111
GeneOntologyBiologicalProcess	regulation of canonical Wnt signaling pathway	ZNF703 HHEX LATS1 LATS2 TLE4 NOTCH1 WNK2	1.40e-04	285	82	7	GO:0060828
GeneOntologyBiologicalProcess	mitral valve formation	ZFPM1 NOTCH1	1.55e-04	5	82	2	GO:0003192
GeneOntologyBiologicalProcess	extrathymic T cell differentiation	ZNF683 PRDM1	1.55e-04	5	82	2	GO:0033078
GeneOntologyBiologicalProcess	definitive hemopoiesis	HOXB3 ZFPM1 LYL1	1.65e-04	27	82	3	GO:0060216
GeneOntologyBiologicalProcess	pericardium development	MECOM TBX20 NOTCH1	1.85e-04	28	82	3	GO:0060039
GeneOntologyBiologicalProcess	Wnt signaling pathway	ZNF703 HHEX LATS1 LATS2 TLE4 SOX30 PKD1 NOTCH1 WNK2	2.08e-04	516	82	9	GO:0016055
GeneOntologyBiologicalProcess	heart valve development	ZFPM1 TBX20 NOTCH1 PRDM1	2.65e-04	78	82	4	GO:0003170
GeneOntologyBiologicalProcess	atrioventricular valve development	ZFPM1 TBX20 NOTCH1	2.76e-04	32	82	3	GO:0003171
GeneOntologyBiologicalProcess	negative regulation of developmental process	NCOR2 HHEX EIF4ENIF1 NFE2 HYAL3 ADGRB1 FBXO7 NR5A1 ZFPM1 DCC CCNK GLIS1 NOTCH1 TBX6	2.99e-04	1220	82	14	GO:0051093
GeneOntologyBiologicalProcess	regulation of NK T cell differentiation	ZNF683 PRDM1	3.24e-04	7	82	2	GO:0051136
GeneOntologyBiologicalProcess	cardiac atrium morphogenesis	ZFPM1 TBX20 NOTCH1	3.62e-04	35	82	3	GO:0003209
GeneOntologyBiologicalProcess	gland development	ZNF703 NCOR2 HOXB3 HHEX GSX1 LATS1 PKD1 NR5A1 NOTCH1	3.69e-04	558	82	9	GO:0048732
GeneOntologyBiologicalProcess	embryonic organ development	HOXB3 HHEX NFE2 PKD1 ZFPM1 TBX20 NOTCH1 PRDM1 TBX6	3.84e-04	561	82	9	GO:0048568
GeneOntologyBiologicalProcess	inner cell mass cell differentiation	LATS1 LATS2	4.30e-04	8	82	2	GO:0001826
GeneOntologyBiologicalProcess	mesenchymal cell development	TBX20 NOTCH1	4.30e-04	8	82	2	GO:0014031
GeneOntologyBiologicalProcess	canonical Wnt signaling pathway	ZNF703 HHEX LATS1 LATS2 TLE4 NOTCH1 WNK2	4.40e-04	344	82	7	GO:0060070
GeneOntologyBiologicalProcess	tricuspid valve development	ZFPM1 TBX20	5.52e-04	9	82	2	GO:0003175
GeneOntologyBiologicalProcess	atrioventricular valve formation	ZFPM1 NOTCH1	5.52e-04	9	82	2	GO:0003190
GeneOntologyBiologicalProcess	pericardium morphogenesis	TBX20 NOTCH1	5.52e-04	9	82	2	GO:0003344
GeneOntologyBiologicalProcess	morphogenesis of a branching structure	HHEX PKD1 RERE TBX20 NOTCH1 PRDM1	5.72e-04	258	82	6	GO:0001763
GeneOntologyBiologicalProcess	protein localization to nucleus	HHEX LATS1 LATS2 EIF4ENIF1 MAVS NR5A1 NOTCH1	5.95e-04	362	82	7	GO:0034504
GeneOntologyBiologicalProcess	cardiac atrium development	ZFPM1 TBX20 NOTCH1	6.22e-04	42	82	3	GO:0003230
GeneOntologyBiologicalProcess	embryonic heart tube development	HHEX TBX20 NOTCH1 TBX6	7.61e-04	103	82	4	GO:0035050
GeneOntologyBiologicalProcess	nuclear transport	CASC3 HHEX EIF4ENIF1 SMG7 MAVS PKD1 NOTCH1	7.68e-04	378	82	7	GO:0051169
GeneOntologyBiologicalProcess	nucleocytoplasmic transport	CASC3 HHEX EIF4ENIF1 SMG7 MAVS PKD1 NOTCH1	7.68e-04	378	82	7	GO:0006913
GeneOntologyBiologicalProcess	heart development	NCOR2 HHEX PKD1 MECOM ZFPM1 TBX20 MMP13 NOTCH1 PRDM1 TBX6	8.23e-04	757	82	10	GO:0007507
GeneOntologyBiologicalProcess	central nervous system development	SETD1A NCOR2 HOXB3 HHEX GSX1 ATN1 MECOM RERE DCC TBX20 MYO16 NOTCH1 NPAS1	8.41e-04	1197	82	13	GO:0007417
GeneOntologyBiologicalProcess	nuclear export	CASC3 HHEX EIF4ENIF1 SMG7 PKD1	8.59e-04	185	82	5	GO:0051168
GeneOntologyBiologicalProcess	negative regulation of protein serine/threonine kinase activity	HHEX LATS1 LATS2 FBXO7	1.04e-03	112	82	4	GO:0071901
GeneOntologyBiologicalProcess	negative regulation of Wnt signaling pathway	LATS1 LATS2 TLE4 SOX30 NOTCH1	1.09e-03	195	82	5	GO:0030178
GeneOntologyBiologicalProcess	venous blood vessel morphogenesis	TBX20 NOTCH1	1.18e-03	13	82	2	GO:0048845
GeneOntologyBiologicalProcess	regulation of cell development	SRRT SETD1A HOXB3 THPO FBXO7 ZNF683 ZFPM1 DCC BHLHE40 NOTCH1 PRDM1 TBX6	1.26e-03	1095	82	12	GO:0060284
GeneOntologyBiologicalProcess	vasculogenesis	HHEX TBX20 NOTCH1 TBX6	1.26e-03	118	82	4	GO:0001570
GeneOntologyBiologicalProcess	regulation of cellular response to growth factor stimulus	ZNF703 HHEX LATS1 LATS2 SKOR1 TBX20 NOTCH1	1.27e-03	412	82	7	GO:0090287
GeneOntologyBiologicalProcess	spinal cord development	GSX1 DCC TBX20 NOTCH1	1.30e-03	119	82	4	GO:0021510
GeneOntologyBiologicalProcess	regulation of stem cell proliferation	SETD1A THPO MECOM NOTCH1	1.30e-03	119	82	4	GO:0072091
GeneOntologyBiologicalProcess	cardiac chamber formation	TBX20 NOTCH1	1.38e-03	14	82	2	GO:0003207
GeneOntologyBiologicalProcess	NK T cell differentiation	ZNF683 PRDM1	1.38e-03	14	82	2	GO:0001865
GeneOntologyCellularComponent	nuclear body	SRRT CASC3 SETD1A NCOR2 HHEX HIVEP1 SLC2A4RG EIF4ENIF1 NFE2 MECOM NHS INAVA RERE BHLHE40	7.54e-06	903	80	14	GO:0016604
GeneOntologyCellularComponent	chromatin	SETD1A NCOR2 HOXB3 HHEX GSX1 NFE2 SOX30 ZBTB22 SHOX DMRTB1 EVX1 NR5A1 ZFPM1 TBX20 LYL1 BHLHE40 NPAS1 TBX6	9.38e-06	1480	80	18	GO:0000785
MousePheno	abnormal pharyngeal arch morphology	HHEX LATS2 MECOM RERE TBX20 NOTCH1 PRDM1	1.39e-05	171	65	7	MP:0002884
MousePheno	abnormal vertebral articular process morphology	MECOM TBX6	2.13e-05	2	65	2	MP:0004602
MousePheno	abnormal megakaryocyte morphology	NCOR2 THPO NFE2 ZFPM1 DCC	4.84e-05	86	65	5	MP:0002417
MousePheno	abnormal bone marrow hematopoietic cell morphology	NCOR2 THPO NFE2 ZFPM1 DCC	1.09e-04	102	65	5	MP:0013660
MousePheno	abnormal megakaryocyte physiology	NFE2 DCC	1.27e-04	4	65	2	MP:0020397
MousePheno	abnormal megakaryocyte emperipolesis	NFE2 DCC	1.27e-04	4	65	2	MP:0020398
MousePheno	enhanced megakaryocyte emperipolesis	NFE2 DCC	1.27e-04	4	65	2	MP:0020399
MousePheno	abnormal craniofacial development	HHEX LATS2 PKD1 MECOM RERE TBX20 NOTCH1 MMACHC PRDM1	1.44e-04	425	65	9	MP:0003935
MousePheno	embryonic lethality during organogenesis	CASC3 HHEX KMT2D LATS2 PKD1 MECOM PDCD2L ZFPM1 RERE TBX20 NOTCH1 PRDM1 TBX6	1.64e-04	876	65	13	MP:0006207
Domain	HTH_motif	HOXB3 HHEX GSX1 SHOX EVX1	1.15e-05	69	80	5	IPR000047
Domain	Atrophin-like	ATN1 RERE	1.81e-05	2	80	2	IPR002951
Domain	Atrophin-1	ATN1 RERE	1.81e-05	2	80	2	PF03154
Domain	LH2	PKD1 PKD1L2 ALOX12B	5.90e-05	18	80	3	SM00308
Domain	PLAT	PKD1 PKD1L2 ALOX12B	9.52e-05	21	80	3	PS50095
Domain	-	PKD1 PKD1L2 ALOX12B	9.52e-05	21	80	3	2.60.60.20
Domain	PLAT	PKD1 PKD1L2 ALOX12B	9.52e-05	21	80	3	PF01477
Domain	PLAT/LH2_dom	PKD1 PKD1L2 ALOX12B	9.52e-05	21	80	3	IPR001024
Domain	REJ	PKD1 PKD1L2	1.08e-04	4	80	2	PS51111
Domain	REJ_dom	PKD1 PKD1L2	1.08e-04	4	80	2	IPR014010
Domain	PKD/REJ-like	PKD1 PKD1L2	2.69e-04	6	80	2	IPR002859
Domain	REJ	PKD1 PKD1L2	2.69e-04	6	80	2	PF02010
Domain	TF_Brachyury	TBX20 TBX6	2.69e-04	6	80	2	IPR002070
Domain	GPS	PKD1 ADGRB1 PKD1L2	4.11e-04	34	80	3	SM00303
Domain	GPS	PKD1 ADGRB1 PKD1L2	4.49e-04	35	80	3	PF01825
Domain	UBA	LATS1 UBAP2 LATS2	4.88e-04	36	80	3	PF00627
Domain	GPS	PKD1 ADGRB1 PKD1L2	4.88e-04	36	80	3	PS50221
Domain	GPS	PKD1 ADGRB1 PKD1L2	5.29e-04	37	80	3	IPR000203
Domain	Homeodomain-like	NCOR2 HOXB3 HHEX GSX1 SHOX EVX1 RERE	5.51e-04	332	80	7	IPR009057
Domain	Homeobox_metazoa	HOXB3 HHEX GSX1 EVX1	6.03e-04	90	80	4	IPR020479
Domain	SET	SETD1A KMT2D PRDM1	7.17e-04	41	80	3	PF00856
Domain	UBA	LATS1 UBAP2 LATS2	8.83e-04	44	80	3	IPR015940
Domain	BAH	RERE BAHCC1	9.72e-04	11	80	2	SM00439
Domain	BAH	RERE BAHCC1	9.72e-04	11	80	2	PF01426
Domain	BAH	RERE BAHCC1	9.72e-04	11	80	2	PS51038
Domain	PKD_channel	PKD1 PKD1L2	9.72e-04	11	80	2	PF08016
Domain	BAH_dom	RERE BAHCC1	9.72e-04	11	80	2	IPR001025
Domain	PKD1_2_channel	PKD1 PKD1L2	9.72e-04	11	80	2	IPR013122
Domain	SET	SETD1A KMT2D PRDM1	1.01e-03	46	80	3	SM00317
Domain	UBA	LATS1 UBAP2 LATS2	1.07e-03	47	80	3	PS50030
Domain	Homeobox_CS	HOXB3 HHEX GSX1 SHOX EVX1	1.22e-03	186	80	5	IPR017970
Domain	SET_dom	SETD1A KMT2D PRDM1	1.28e-03	50	80	3	IPR001214
Domain	SET	SETD1A KMT2D PRDM1	1.28e-03	50	80	3	PS50280
Domain	-	NCOR2 HOXB3 HHEX GSX1 SHOX EVX1	1.35e-03	283	80	6	1.10.10.60
Domain	Post-SET_dom	SETD1A KMT2D	2.09e-03	16	80	2	IPR003616
Domain	PostSET	SETD1A KMT2D	2.09e-03	16	80	2	SM00508
Domain	POST_SET	SETD1A KMT2D	2.09e-03	16	80	2	PS50868
Domain	TF_T-box	TBX20 TBX6	2.36e-03	17	80	2	IPR001699
Domain	TBOX	TBX20 TBX6	2.36e-03	17	80	2	SM00425
Domain	TF_T-box_CS	TBX20 TBX6	2.36e-03	17	80	2	IPR018186
Domain	-	TBX20 TBX6	2.36e-03	17	80	2	2.60.40.820
Domain	TBOX_3	TBX20 TBX6	2.36e-03	17	80	2	PS50252
Domain	T-box	TBX20 TBX6	2.36e-03	17	80	2	PF00907
Domain	TBOX_1	TBX20 TBX6	2.36e-03	17	80	2	PS01283
Domain	TBOX_2	TBX20 TBX6	2.36e-03	17	80	2	PS01264
Domain	UBA-like	LATS1 UBAP2 LATS2	2.61e-03	64	80	3	IPR009060
Domain	Znf_C2H2/integrase_DNA-bd	ZNF703 HIVEP1 SLC2A4RG ZBTB22 MECOM ZNF683 ZFPM1 GLIS1 PRDM1	2.83e-03	694	80	9	IPR013087
Domain	Homeobox	HOXB3 HHEX GSX1 SHOX EVX1	3.32e-03	234	80	5	PF00046
Domain	HOMEOBOX_1	HOXB3 HHEX GSX1 SHOX EVX1	3.44e-03	236	80	5	PS00027
Domain	HOX	HOXB3 HHEX GSX1 SHOX EVX1	3.50e-03	237	80	5	SM00389
Domain	HOMEOBOX_2	HOXB3 HHEX GSX1 SHOX EVX1	3.63e-03	239	80	5	PS50071
Domain	Homeobox_dom	HOXB3 HHEX GSX1 SHOX EVX1	3.63e-03	239	80	5	IPR001356
Domain	SANT_dom	NCOR2 RERE	5.51e-03	26	80	2	IPR017884
Domain	ZINC_FINGER_C2H2_2	ZNF703 HIVEP1 SLC2A4RG ZBTB22 MECOM ZNF683 ZFPM1 GLIS1 PRDM1	5.81e-03	775	80	9	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF703 HIVEP1 SLC2A4RG ZBTB22 MECOM ZNF683 ZFPM1 GLIS1 PRDM1	5.90e-03	777	80	9	PS00028
Domain	SANT	NCOR2 RERE	6.37e-03	28	80	2	PS51293
Domain	Znf_C2H2-like	ZNF703 HIVEP1 SLC2A4RG ZBTB22 MECOM ZNF683 ZFPM1 GLIS1 PRDM1	6.88e-03	796	80	9	IPR015880
Domain	Znf_C2H2	ZNF703 HIVEP1 SLC2A4RG ZBTB22 MECOM ZNF683 ZFPM1 GLIS1 PRDM1	7.39e-03	805	80	9	IPR007087
Domain	ZnF_C2H2	ZNF703 HIVEP1 SLC2A4RG ZBTB22 MECOM ZNF683 ZFPM1 GLIS1 PRDM1	7.56e-03	808	80	9	SM00355
Domain	-	ZNF703 HIVEP1 ZBTB22 MECOM ZNF683 ZFPM1 GLIS1 PRDM1	8.50e-03	679	80	8	3.30.160.60
Pubmed	A census of human transcription factors: function, expression and evolution.	HOXB3 HHEX GSX1 KMT2D HIVEP1 NFE2 SOX30 SKOR1 SHOX DMRTB1 EVX1 NR5A1 ZFPM1 RERE TBX20 LYL1 BHLHE40 GLIS1 NPAS1 PRDM1 TBX6	2.40e-15	908	83	21	19274049
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	GSX1 NFE2 SOX30 ZBTB22 SKOR1 SHOX EVX1 NR5A1 TBX20 BHLHE40 GLIS1 PRDM1 TBX6	5.67e-10	544	83	13	28473536
Pubmed	Interaction network of human early embryonic transcription factors.	ZNF703 SETD1A NCOR2 KMT2D HIVEP1 ATN1 TLE4 FBRS MECOM RERE BAHCC1	7.99e-10	351	83	11	38297188
Pubmed	Human transcription factor protein interaction networks.	SRRT ZNF703 SETD1A NCOR2 IGF2BP2 KMT2D HIVEP1 UBAP2 ATN1 EIF4ENIF1 SMG7 TLE4 FBRS OTUD4 MECOM SRP68 RERE PRRC2A PRDM1	8.49e-10	1429	83	19	35140242
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MST1R SETD1A NCOR2 KMT2D SLC2A4RG LATS2 EIF4ENIF1 MORN1 PPRC1 PKD1 FBRS ZFPM1 NOTCH1 WNK2 ARHGAP33 BAHCC1	6.79e-09	1105	83	16	35748872
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SETD1A NCOR2 LATS1 UBAP2 ATN1 EIF4ENIF1 SPATA31E1 INAVA NOTCH1 WNK2	8.19e-08	430	83	10	35044719
Pubmed	Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators.	HHEX NFE2 ZFPM1 LYL1	8.99e-08	18	83	4	20887958
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SRRT NCOR2 KMT2D HIVEP1 LATS1 ATN1 TLE4 OTUD4 ZFPM1 RERE PRRC2A CCNK	3.10e-07	774	83	12	15302935
Pubmed	Histone deacetylase-associating Atrophin proteins are nuclear receptor corepressors.	NCOR2 ATN1 RERE	4.56e-07	7	83	3	16481466
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	HIVEP1 ATN1 EIF4ENIF1 DMRTB1 RERE PRRC2A CCNK NOTCH1 WNK2 PRDM1	1.92e-06	608	83	10	16713569
Pubmed	Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells.	LATS1 LATS2 MAP3K14	2.13e-06	11	83	3	29849151
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	KMT2D HIVEP1 ATN1 TLE4 FBRS RERE CCNK	3.76e-06	268	83	7	33640491
Pubmed	SOX9 modulates the expression of key transcription factors required for heart valve development.	MECOM TBX20 BHLHE40	4.68e-06	14	83	3	26525672
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	NCOR2 KRBA1 KMT2D SMG7 MECOM NOTCH1	5.44e-06	184	83	6	32908313
Pubmed	Mutation analysis of large tumor suppressor genes LATS1 and LATS2 supports a tumor suppressor role in human cancer.	LATS1 LATS2	5.63e-06	2	83	2	25482410
Pubmed	Blimp-1 Rather Than Hobit Drives the Formation of Tissue-Resident Memory CD8+ T Cells in the Lungs.	ZNF683 PRDM1	5.63e-06	2	83	2	30899267
Pubmed	Lats1/2-Mediated Alteration of Hippo Signaling Pathway Regulates the Fate of Bone Marrow-Derived Mesenchymal Stem Cells.	LATS1 LATS2	5.63e-06	2	83	2	30671453
Pubmed	Protein binding of a DRPLA family through arginine-glutamic acid dipeptide repeats is enhanced by extended polyglutamine.	ATN1 RERE	5.63e-06	2	83	2	10814707
Pubmed	Notch1 regulates hepatic thrombopoietin production.	THPO NOTCH1	5.63e-06	2	83	2	38603632
Pubmed	A single copy of large tumor suppressor 1 or large tumor suppressor 2 is sufficient for normal hematopoiesis.	LATS1 LATS2	5.63e-06	2	83	2	32826458
Pubmed	AICAR Antiproliferative Properties Involve the AMPK-Independent Activation of the Tumor Suppressors LATS 1 and 2.	LATS1 LATS2	5.63e-06	2	83	2	29730476
Pubmed	N-terminal truncation of Lats1 causes abnormal cell growth control and chromosomal instability.	LATS1 LATS2	5.63e-06	2	83	2	23230145
Pubmed	LATS1 but not LATS2 represses autophagy by a kinase-independent scaffold function.	LATS1 LATS2	5.63e-06	2	83	2	31848340
Pubmed	Expression of LATS family proteins in ovarian tumors and its significance.	LATS1 LATS2	5.63e-06	2	83	2	25841306
Pubmed	Evidence for a tumor suppressor role for the large tumor suppressor genes LATS1 and LATS2 in human cancer.	LATS1 LATS2	5.63e-06	2	83	2	24026096
Pubmed	Association analysis between SNPs in LATS1 and LATS2 and non-cardia gastric cancer.	LATS1 LATS2	5.63e-06	2	83	2	32423384
Pubmed	Deletion of Lats1/2 in adult kidney epithelia leads to renal cell carcinoma.	LATS1 LATS2	5.63e-06	2	83	2	34060480
Pubmed	Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma.	LATS1 LATS2	5.63e-06	2	83	2	17049657
Pubmed	Lats1 and Lats2 are required for ovarian granulosa cell fate maintenance.	LATS1 LATS2	5.63e-06	2	83	2	31268774
Pubmed	Hobit- and Blimp-1-driven CD4+ tissue-resident memory T cells control chronic intestinal inflammation.	ZNF683 PRDM1	5.63e-06	2	83	2	30692620
Pubmed	The Hippo pathway regulates human megakaryocytic differentiation.	LATS1 LATS2	5.63e-06	2	83	2	27786336
Pubmed	Hobit and Blimp-1 regulate TRM abundance after LCMV infection by suppressing tissue exit pathways of TRM precursors.	ZNF683 PRDM1	5.63e-06	2	83	2	35389518
Pubmed	Cell type-dependent function of LATS1/2 in cancer cell growth.	LATS1 LATS2	5.63e-06	2	83	2	30531839
Pubmed	Zeppo1 is a novel metastasis promoter that represses E-cadherin expression and regulates p120-catenin isoform expression and localization.	ZNF703 TLE4	5.63e-06	2	83	2	21317240
Pubmed	Nuclear Factor Erythroid 2 Regulates Human HSC Self-Renewal and T Cell Differentiation by Preventing NOTCH1 Activation.	NFE2 NOTCH1	5.63e-06	2	83	2	28648895
Pubmed	Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers.	LATS1 LATS2	5.63e-06	2	83	2	15746036
Pubmed	Identification of LATS transcriptional targets in HeLa cells using whole human genome oligonucleotide microarray.	LATS1 LATS2	5.63e-06	2	83	2	19799973
Pubmed	LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control.	LATS1 LATS2	5.63e-06	2	83	2	32015438
Pubmed	Blimp-1 induces and Hobit maintains the cytotoxic mediator granzyme B in CD8 T cells.	ZNF683 PRDM1	5.63e-06	2	83	2	30051906
Pubmed	A novel immuno-competitive capture mass spectrometry strategy for protein-protein interaction profiling reveals that LATS kinases regulate HCV replication through NS5A phosphorylation.	LATS1 LATS2	5.63e-06	2	83	2	25044019
Pubmed	The bHLH transcription factor DEC1 promotes thyroid cancer aggressiveness by the interplay with NOTCH1.	BHLHE40 NOTCH1	5.63e-06	2	83	2	30158530
Pubmed	Dysplastic definitive hematopoiesis in AML1/EVI1 knock-in embryos.	NFE2 MECOM ZFPM1	7.18e-06	16	83	3	15914564
Pubmed	A 5' untranslated region containing the IRES element in the Runx1 gene is required for angiogenesis, hematopoiesis and leukemogenesis in a knock-in mouse model.	NFE2 MECOM ZFPM1	7.18e-06	16	83	3	20647008
Pubmed	Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks.	HHEX EVX1 TBX6	7.18e-06	16	83	3	12431380
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	NCOR2 KMT2D HIVEP1 EIF4ENIF1 TLE4 FBRS MECOM RERE	7.31e-06	418	83	8	34709266
Pubmed	A FUS-LATS1/2 Axis Inhibits Hepatocellular Carcinoma Progression via Activating Hippo Pathway.	LATS1 LATS2	1.69e-05	3	83	2	30308519
Pubmed	Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomas.	KMT2D NOTCH1	1.69e-05	3	83	2	27566587
Pubmed	Peripheral and systemic antigens elicit an expandable pool of resident memory CD8+ T cells in the bone marrow.	ZNF683 PRDM1	1.69e-05	3	83	2	30891737
Pubmed	Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2.	LATS1 LATS2	1.69e-05	3	83	2	24012335
Pubmed	Atrophin proteins interact with the Fat1 cadherin and regulate migration and orientation in vascular smooth muscle cells.	ATN1 RERE	1.69e-05	3	83	2	19131340
Pubmed	LATS kinases and SLUG regulate the transition to advanced stage in aggressive oral cancer cells.	LATS1 LATS2	1.69e-05	3	83	2	35859006
Pubmed	The Inhibitory Receptor GPR56 (Adgrg1) Is Specifically Expressed by Tissue-Resident Memory T Cells in Mice But Dispensable for Their Differentiation and Function In Vivo.	ZNF683 PRDM1	1.69e-05	3	83	2	34685654
Pubmed	Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway.	LATS1 LATS2	1.69e-05	3	83	2	18413746
Pubmed	Tumor suppressor LATS1 is a negative regulator of oncogene YAP.	LATS1 LATS2	1.69e-05	3	83	2	18158288
Pubmed	Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo.	HHEX EVX1 TBX6	1.69e-05	21	83	3	10421635
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	ZNF703 SETD1A KMT2D HIVEP1 ATN1 FBRS FBXO7 RERE	2.47e-05	495	83	8	27705803
Pubmed	Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse.	LATS1 LATS2 TBX6	2.90e-05	25	83	3	19786569
Pubmed	Homeostatic and tumourigenic activity of SOX2+ pituitary stem cells is controlled by the LATS/YAP/TAZ cascade.	LATS1 LATS2 NR5A1	2.90e-05	25	83	3	30912742
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	ZNF703 NCOR2 ATN1 FBRS CCNK	3.29e-05	152	83	5	38360978
Pubmed	Src Inhibits the Hippo Tumor Suppressor Pathway through Tyrosine Phosphorylation of Lats1.	LATS1 LATS2	3.37e-05	4	83	2	28754671
Pubmed	Interleukin-1beta up-regulates the expression of thrombopoietin and transcription factors c-Jun, c-Fos, GATA-1, and NF-E2 in megakaryocytic cells.	THPO NFE2	3.37e-05	4	83	2	14966463
Pubmed	Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP.	LATS1 LATS2	3.37e-05	4	83	2	21041411
Pubmed	Hippo signalling maintains ER expression and ER+ breast cancer growth.	LATS1 LATS2	3.37e-05	4	83	2	33658690
Pubmed	Heat shock protein 90 inhibition depletes LATS1 and LATS2, two regulators of the mammalian hippo tumor suppressor pathway.	LATS1 LATS2	3.37e-05	4	83	2	20841485
Pubmed	WWC1 and NF2 Prevent the Development of Intrahepatic Cholangiocarcinoma by Regulating YAP/TAZ Activity through LATS in Mice.	LATS1 LATS2	3.37e-05	4	83	2	32451369
Pubmed	Wnt5a controls Notch1 signaling through CaMKII-mediated degradation of the SMRT corepressor protein.	NCOR2 NOTCH1	3.37e-05	4	83	2	22888005
Pubmed	Presomitic mesoderm-specific expression of the transcriptional repressor Hes7 is controlled by E-box, T-box, and Notch signaling pathways.	NOTCH1 TBX6	3.37e-05	4	83	2	29895619
Pubmed	SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function.	NCOR2 NOTCH1	3.37e-05	4	83	2	10713164
Pubmed	Phosphorylation of CHO1 by Lats1/2 regulates the centrosomal activation of LIMK1 during cytokinesis.	LATS1 LATS2	3.37e-05	4	83	2	25786116
Pubmed	Hippo signaling instructs ectopic but not normal organ growth.	LATS1 LATS2	3.37e-05	4	83	2	36395225
Pubmed	Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity.	LATS1 LATS2	3.37e-05	4	83	2	15343267
Pubmed	LncRNA HCG11 mediated by METTL14 inhibits the growth of lung adenocarcinoma via IGF2BP2/LATS1.	IGF2BP2 LATS1	3.37e-05	4	83	2	34624573
Pubmed	Inactivation of the Hippo tumor suppressor pathway promotes melanoma.	LATS1 LATS2	3.37e-05	4	83	2	35768444
Pubmed	KIBRA regulates Hippo signaling activity via interactions with large tumor suppressor kinases.	LATS1 LATS2	3.37e-05	4	83	2	21233212
Pubmed	The tumor suppressor Lats2 is pivotal in Aurora A and Aurora B signaling during mitosis.	LATS1 LATS2	3.37e-05	4	83	2	21822051
Pubmed	Functional architecture of atrophins.	ATN1 RERE	3.37e-05	4	83	2	17150957
Pubmed	RASSF1A-Mediated Suppression of Estrogen Receptor Alpha (ERα)-Driven Breast Cancer Cell Growth Depends on the Hippo-Kinases LATS1 and 2.	LATS1 LATS2	3.37e-05	4	83	2	34831091
Pubmed	Binding of Kif23-iso1/CHO1 to 14-3-3 is regulated by sequential phosphorylations at two LATS kinase consensus sites.	LATS1 LATS2	3.37e-05	4	83	2	25658096
Pubmed	Thrombopoietin/MPL signaling confers growth and survival capacity to CD41-positive cells in a mouse model of Evi1 leukemia.	THPO MECOM	3.37e-05	4	83	2	25298035
Pubmed	Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight.	HHEX IGF2BP2 NOTCH1	3.68e-05	27	83	3	20490451
Pubmed	Tbx20 acts upstream of Wnt signaling to regulate endocardial cushion formation and valve remodeling during mouse cardiogenesis.	TBX20 MMP13 NOTCH1	3.68e-05	27	83	3	23824573
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	ZNF703 NCOR2 KMT2D HIVEP1 FBRS MECOM BAHCC1	4.79e-05	398	83	7	35016035
Pubmed	HAND2 Target Gene Regulatory Networks Control Atrioventricular Canal and Cardiac Valve Development.	HHEX TBX20 NOTCH1	5.08e-05	30	83	3	28538179
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SETD1A KMT2D LATS1 UBAP2 SMG7 SRP68 PRRC2A CCNK	5.12e-05	549	83	8	38280479
Pubmed	Phosphorylation of angiomotin by Lats1/2 kinases inhibits F-actin binding, cell migration, and angiogenesis.	LATS1 LATS2	5.60e-05	5	83	2	24106267
Pubmed	The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα.	LATS1 LATS2	5.60e-05	5	83	2	28068668
Pubmed	Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway.	LATS1 LATS2	5.60e-05	5	83	2	26045165
Pubmed	The Hippo pathway links adipocyte plasticity to adipose tissue fibrosis.	LATS1 LATS2	5.60e-05	5	83	2	36229481
Pubmed	Control of skeletal morphogenesis by the Hippo-YAP/TAZ pathway.	LATS1 LATS2	5.60e-05	5	83	2	32994166
Pubmed	Differential NDR/LATS interactions with the human MOB family reveal a negative role for human MOB2 in the regulation of human NDR kinases.	LATS1 LATS2	5.60e-05	5	83	2	20624913
Pubmed	Myofibroblast YAP/TAZ activation is a key step in organ fibrogenesis.	LATS1 LATS2	5.60e-05	5	83	2	35191398
Pubmed	Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP.	LATS1 LATS2	5.60e-05	5	83	2	26109051
Pubmed	Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis.	LATS1 LATS2	5.60e-05	5	83	2	29438698
Pubmed	Mint represses transactivation of the type II collagen gene enhancer through interaction with alpha A-crystallin-binding protein 1.	NCOR2 HIVEP1	5.60e-05	5	83	2	15778499
Pubmed	The Hippo Pathway Blocks Mammalian Retinal Müller Glial Cell Reprogramming.	LATS1 LATS2	5.60e-05	5	83	2	31067451
Pubmed	Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes.	ZNF683 PRDM1	5.60e-05	5	83	2	27102484
Pubmed	Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse.	LATS1 LATS2	5.60e-05	5	83	2	31474569
Pubmed	Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP).	LATS1 LATS2	5.60e-05	5	83	2	18640976
Pubmed	Cloning and characterization of mCtBP2, a co-repressor that associates with basic Krüppel-like factor and other mammalian transcriptional regulators.	MECOM ZFPM1	5.60e-05	5	83	2	9724649
Pubmed	Grg3, a murine Groucho-related gene, is expressed in the developing nervous system and in mesenchyme-induced epithelial structures.	TLE4 NOTCH1	5.60e-05	5	83	2	8989517
Interaction	ALG13 interactions	ZNF703 NCOR2 IGF2BP2 KMT2D LATS1 ATN1 EIF4ENIF1 SMG7 FBRS OTUD4 DMRTB1 RERE PRRC2A CCNK	1.68e-14	183	81	14	int:ALG13
Interaction	TLE3 interactions	SRRT ZNF703 NCOR2 HHEX KMT2D HIVEP1 ATN1 SMG7 TLE4 FBRS FBXO7 OTUD4 RERE TBX20 NOTCH1 PRDM1	1.75e-12	376	81	16	int:TLE3
Interaction	GSC interactions	ZNF703 NCOR2 KMT2D HIVEP1 ATN1 TLE4 FBRS MECOM RERE BAHCC1	1.93e-12	87	81	10	int:GSC
Interaction	SMG7 interactions	ZNF703 NCOR2 IGF2BP2 KMT2D HIVEP1 LATS1 EIF4ENIF1 SMG7 TLE4 OTUD4 MECOM PRRC2A NPAS1	4.39e-10	319	81	13	int:SMG7
Interaction	FXR2 interactions	HIVEP1 LATS1 UBAP2 ATN1 EIF4ENIF1 SMG7 MAP3K14 ZBTB22 OTUD4 MECOM SRP68 DMRTB1 INAVA PRRC2A	1.63e-09	430	81	14	int:FXR2
Interaction	TBR1 interactions	MST1R ZNF703 NCOR2 KMT2D HIVEP1 LATS1 TLE4 FBRS	1.74e-08	113	81	8	int:TBR1
Interaction	RBM47 interactions	CASC3 IGF2BP2 HIVEP1 UBAP2 EIF4ENIF1 SMG7 OTUD4 SRP68 PRRC2A	1.30e-07	204	81	9	int:RBM47
Interaction	TLE5 interactions	HHEX UBAP2 ATN1 SMG7 TLE4 MECOM DMRTB1 BHLHE40 CCNK NPAS1 PRDM1 TBX6	1.97e-07	443	81	12	int:TLE5
Interaction	RBFOX2 interactions	UBAP2 ATN1 EIF4ENIF1 FBXO7 OTUD4 MECOM SRP68 DMRTB1 RERE PRRC2A	2.05e-07	284	81	10	int:RBFOX2
Interaction	TOP3B interactions	MST1R SETD1A NCOR2 IGF2BP2 KMT2D UBAP2 SLC2A4RG LATS2 EIF4ENIF1 SMG7 MORN1 PPRC1 PKD1 FBRS OTUD4 ZFPM1 PRRC2A NOTCH1 WNK2 ARHGAP33 BAHCC1	2.25e-07	1470	81	21	int:TOP3B
Interaction	SP7 interactions	SRRT ZNF703 NCOR2 HHEX KMT2D HIVEP1 ATN1 TLE4 FBRS RERE	3.84e-07	304	81	10	int:SP7
Interaction	TBXT interactions	ZNF703 NCOR2 KMT2D HIVEP1 ATN1 TLE4 FBRS	4.27e-07	116	81	7	int:TBXT
Interaction	EGR2 interactions	NCOR2 KMT2D HIVEP1 ATN1 FBRS MECOM RERE BAHCC1	4.33e-07	171	81	8	int:EGR2
Interaction	PRRC2A interactions	CASC3 IGF2BP2 UBAP2 ATN1 EIF4ENIF1 SMG7 FBXO7 OTUD4 SRP68 RERE PRRC2A	4.35e-07	389	81	11	int:PRRC2A
Interaction	SECISBP2 interactions	IGF2BP2 EIF4ENIF1 SMG7 OTUD4 DMRTB1 PRRC2A	7.12e-07	78	81	6	int:SECISBP2
Interaction	KRTAP6-2 interactions	CASC3 HHEX ATN1 ZNF683 RERE BHLHE40 CCNK TBX6	8.54e-07	187	81	8	int:KRTAP6-2
Interaction	R3HDM2 interactions	CASC3 IGF2BP2 UBAP2 EIF4ENIF1 SMG7 OTUD4 PRRC2A	8.77e-07	129	81	7	int:R3HDM2
Interaction	R3HDM1 interactions	IGF2BP2 LATS1 EIF4ENIF1 SMG7 OTUD4 PRRC2A	1.11e-06	84	81	6	int:R3HDM1
Interaction	BAG2 interactions	ZNF703 SETD1A FKBP15 UBAP2 LATS2 EIF4ENIF1 MAVS TLE4 MAP3K14 FBXO7 OTUD4 MECOM NPAS1	1.11e-06	622	81	13	int:BAG2
Interaction	PRRC2B interactions	IGF2BP2 ATN1 EIF4ENIF1 SMG7 FBXO7 OTUD4 DMRTB1 RERE PRRC2A	1.17e-06	265	81	9	int:PRRC2B
Interaction	GATA2 interactions	ZNF703 NCOR2 HHEX KMT2D HIVEP1 TLE4 FBRS ZFPM1	1.36e-06	199	81	8	int:GATA2
Interaction	FEV interactions	ZNF703 SETD1A NCOR2 KMT2D HIVEP1 TLE4 FBRS MECOM	1.58e-06	203	81	8	int:FEV
Interaction	PRR20B interactions	HIVEP1 EIF4ENIF1 ZNF683 BHLHE40 CCNK TBX6	1.66e-06	90	81	6	int:PRR20B
Interaction	PRR20C interactions	HIVEP1 EIF4ENIF1 ZNF683 BHLHE40 CCNK TBX6	1.66e-06	90	81	6	int:PRR20C
Interaction	PRR20D interactions	HIVEP1 EIF4ENIF1 ZNF683 BHLHE40 CCNK TBX6	1.66e-06	90	81	6	int:PRR20D
Interaction	DAZL interactions	CASC3 IGF2BP2 UBAP2 EIF4ENIF1 SMG7 OTUD4 PRRC2A	1.92e-06	145	81	7	int:DAZL
Interaction	NFIC interactions	NCOR2 KMT2D HIVEP1 LATS2 FBRS FBXO7 GLIS1 PRDM1	2.04e-06	210	81	8	int:NFIC
Interaction	CPEB4 interactions	IGF2BP2 UBAP2 EIF4ENIF1 SMG7 FBXO7 OTUD4 PRRC2A	3.13e-06	156	81	7	int:CPEB4
Interaction	PRR20E interactions	HIVEP1 EIF4ENIF1 ZNF683 BHLHE40 CCNK TBX6	3.27e-06	101	81	6	int:PRR20E
Interaction	PRR20A interactions	HIVEP1 EIF4ENIF1 ZNF683 BHLHE40 CCNK TBX6	5.09e-06	109	81	6	int:PRR20A
Interaction	LARP4B interactions	CASC3 IGF2BP2 UBAP2 EIF4ENIF1 OTUD4 DMRTB1 PRRC2A NPAS1	5.48e-06	240	81	8	int:LARP4B
Interaction	TLX1 interactions	ZNF703 NCOR2 KMT2D HIVEP1 ATN1 TLE4 FBRS	6.69e-06	175	81	7	int:TLX1
Interaction	HDAC1 interactions	SRRT NCOR2 KMT2D HIVEP1 LATS2 EIF4ENIF1 TLE4 FBRS SKOR1 MECOM ZFPM1 RERE BHLHE40 NOTCH1 BAHCC1 PRDM1	7.14e-06	1108	81	16	int:HDAC1
Interaction	CRX interactions	NCOR2 KMT2D ATN1 FBRS MECOM RERE BAHCC1 TBX6	8.29e-06	254	81	8	int:CRX
Interaction	HELZ interactions	NCOR2 IGF2BP2 EIF4ENIF1 SMG7 FBRS OTUD4 PRRC2A NPAS1	9.04e-06	257	81	8	int:HELZ
Interaction	PAX7 interactions	ZNF703 NCOR2 KMT2D HIVEP1 TLE4 FBRS	1.07e-05	124	81	6	int:PAX7
Interaction	PAX9 interactions	ZNF703 NCOR2 KMT2D ATN1 TLE4 FBRS	1.40e-05	130	81	6	int:PAX9
Interaction	TNRC6B interactions	IGF2BP2 LATS1 LATS2 EIF4ENIF1 SMG7 FBRS OTUD4 PRRC2A	1.77e-05	282	81	8	int:TNRC6B
Interaction	RBMS1 interactions	CASC3 IGF2BP2 UBAP2 EIF4ENIF1 SMG7 OTUD4 PRRC2A	1.99e-05	207	81	7	int:RBMS1
Interaction	CELF1 interactions	ZNF703 IGF2BP2 UBAP2 EIF4ENIF1 SMG7 OTUD4 PRRC2A NOTCH1	2.06e-05	288	81	8	int:CELF1
Interaction	MOB3A interactions	LATS1 LATS2 FBXO7	2.21e-05	14	81	3	int:MOB3A
Interaction	SMG5 interactions	IGF2BP2 EIF4ENIF1 SMG7 OTUD4 PRRC2A	2.23e-05	84	81	5	int:SMG5
Interaction	TDRD3 interactions	CASC3 IGF2BP2 LATS1 EIF4ENIF1 SMG7 OTUD4 PRRC2A	2.32e-05	212	81	7	int:TDRD3
Interaction	USP54 interactions	LATS1 LATS2 ATN1 BHLHE40 PRRC2A CCNK TBX6	2.32e-05	212	81	7	int:USP54
Interaction	CREBBP interactions	SETD1A NCOR2 HOXB3 KMT2D HIVEP1 LATS1 EIF4ENIF1 SMG7 NFE2 MECOM NR5A1	2.68e-05	599	81	11	int:CREBBP
Interaction	CPEB1 interactions	IGF2BP2 UBAP2 EIF4ENIF1 SMG7 OTUD4 PRRC2A	2.71e-05	146	81	6	int:CPEB1
Interaction	YTHDF1 interactions	IGF2BP2 UBAP2 EIF4ENIF1 SMG7 OTUD4 DMRTB1 PRRC2A NPAS1	2.89e-05	302	81	8	int:YTHDF1
Interaction	MEX3B interactions	CASC3 IGF2BP2 UBAP2 EIF4ENIF1 SMG7 OTUD4 PRRC2A	3.12e-05	222	81	7	int:MEX3B
Interaction	SAV1 interactions	IGF2BP2 LATS1 LATS2 EIF4ENIF1 INAVA NPAS1	3.27e-05	151	81	6	int:SAV1
Interaction	FOXI1 interactions	ZNF703 NCOR2 KMT2D TLE4 FBRS	3.46e-05	92	81	5	int:FOXI1
Interaction	YTHDF2 interactions	CASC3 IGF2BP2 UBAP2 EIF4ENIF1 SMG7 MAP3K14 OTUD4 PRRC2A	3.64e-05	312	81	8	int:YTHDF2
Interaction	ZNF608 interactions	SETD1A ATN1 SMG7 RERE PRDM1	3.65e-05	93	81	5	int:ZNF608
Interaction	OTUD4 interactions	IGF2BP2 LATS1 EIF4ENIF1 SMG7 MAVS OTUD4 PRRC2A	4.60e-05	236	81	7	int:OTUD4
Interaction	FMR1 interactions	CASC3 NCOR2 IGF2BP2 UBAP2 EIF4ENIF1 SMG7 TLE4 OTUD4 INAVA PRRC2A	5.62e-05	536	81	10	int:FMR1
Interaction	YTHDF3 interactions	IGF2BP2 UBAP2 EIF4ENIF1 SMG7 OTUD4 DMRTB1 PRRC2A	5.98e-05	246	81	7	int:YTHDF3
Interaction	CEP85 interactions	LATS1 LATS2 EIF4ENIF1 SMG7 OTUD4 PRRC2A	6.14e-05	169	81	6	int:CEP85
Interaction	GATA1 interactions	NCOR2 KMT2D ZBTB22 FBRS MECOM ZFPM1	6.55e-05	171	81	6	int:GATA1
Interaction	TAF1 interactions	KMT2D ATN1 EIF4ENIF1 FBRS RERE NOTCH1 NPAS1	8.46e-05	260	81	7	int:TAF1
Interaction	PAX8 interactions	ZNF703 NCOR2 KMT2D HIVEP1 TLE4	8.50e-05	111	81	5	int:PAX8
Interaction	KRTAP19-7 interactions	GSX1 RNF44 OTUD4 BHLHE40 CCNK	1.09e-04	117	81	5	int:KRTAP19-7
Interaction	SMAP2 interactions	UBAP2 EIF4ENIF1 SMG7 OTUD4 BHLHE40 PRRC2A	1.14e-04	189	81	6	int:SMAP2
Interaction	PHIP interactions	NCOR2 IGF2BP2 EIF4ENIF1 SMG7 MECOM RERE	1.43e-04	197	81	6	int:PHIP
Interaction	PUM1 interactions	IGF2BP2 LATS1 UBAP2 EIF4ENIF1 SMG7 OTUD4 PRRC2A	1.56e-04	287	81	7	int:PUM1
Interaction	TLX3 interactions	ZNF703 NCOR2 KMT2D HIVEP1 TLE4 FBRS RERE	1.70e-04	291	81	7	int:TLX3
Interaction	TENT5B interactions	HIVEP1 UBAP2 BHLHE40 TBX6	1.72e-04	69	81	4	int:TENT5B
Interaction	MAGED1 interactions	HIVEP1 FBXO7 BHLHE40 PRRC2A NOTCH1 NPAS1 TBX6	1.85e-04	295	81	7	int:MAGED1
Interaction	CXXC1 interactions	SETD1A KMT2D ATN1 NR5A1 RERE	1.92e-04	132	81	5	int:CXXC1
Interaction	NUP43 interactions	SRRT ZNF703 SETD1A NCOR2 KMT2D HIVEP1 ATN1 EIF4ENIF1 MAVS RERE	1.98e-04	625	81	10	int:NUP43
Interaction	EIF4ENIF1 interactions	IGF2BP2 LATS2 EIF4ENIF1 SMG7 OTUD4 PRRC2A NPAS1	2.05e-04	300	81	7	int:EIF4ENIF1
Interaction	TLE1 interactions	HHEX ATN1 SMG7 TLE4 TBX20 PRDM1	2.18e-04	213	81	6	int:TLE1
Interaction	ZC3H7A interactions	IGF2BP2 UBAP2 EIF4ENIF1 SMG7 OTUD4 PRRC2A	2.29e-04	215	81	6	int:ZC3H7A
Interaction	SETD1B interactions	SETD1A KMT2D ATN1 RERE	2.37e-04	75	81	4	int:SETD1B
Interaction	CHST15 interactions	CASC3 HIVEP1 SLC35E1	2.59e-04	31	81	3	int:CHST15
Interaction	ATXN2 interactions	CASC3 IGF2BP2 EIF4ENIF1 SMG7 OTUD4 SRP68 PRRC2A	2.60e-04	312	81	7	int:ATXN2
Interaction	CRABP2 interactions	SRRT GSX1 HIVEP1 LATS1	2.76e-04	78	81	4	int:CRABP2
Interaction	ERG interactions	ZNF703 NCOR2 KMT2D HIVEP1 FBRS RERE	2.79e-04	223	81	6	int:ERG
Interaction	WWTR1 interactions	KMT2D LATS1 UBAP2 LATS2 SMG7 SRP68 PRRC2A NOTCH1	2.93e-04	422	81	8	int:WWTR1
Interaction	ANKRD17 interactions	UBAP2 EIF4ENIF1 SMG7 OTUD4 PDCD2L PRRC2A	3.00e-04	226	81	6	int:ANKRD17
Interaction	NUP35 interactions	NCOR2 GSX1 KMT2D ATN1 EIF4ENIF1 SMG7 MAVS FBRS	3.02e-04	424	81	8	int:NUP35
Interaction	KLF3 interactions	SETD1A NCOR2 KMT2D HIVEP1 FBRS MECOM	3.14e-04	228	81	6	int:KLF3
Interaction	RUNX1 interactions	NCOR2 RNF44 PKD1 SRP68 PRRC2A CCNK NOTCH1	3.27e-04	324	81	7	int:RUNX1
Interaction	SOX7 interactions	NCOR2 KMT2D FBRS BAHCC1	3.34e-04	82	81	4	int:SOX7
Interaction	KLF8 interactions	SETD1A NCOR2 KMT2D HIVEP1 FBRS MECOM PRRC2A	3.58e-04	329	81	7	int:KLF8
Interaction	KDM1A interactions	NCOR2 KMT2D HIVEP1 EIF4ENIF1 SMG7 TLE4 FBRS MECOM ZFPM1 RERE NOTCH1 PRDM1	3.62e-04	941	81	12	int:KDM1A
Interaction	TENT5A interactions	RNF44 SLC35E1 DMRTB1 BHLHE40	3.66e-04	84	81	4	int:TENT5A
Interaction	PRDM1 interactions	ZNF703 NCOR2 TLE4 PRDM1	3.66e-04	84	81	4	int:PRDM1
Interaction	PAX2 interactions	ZNF703 NCOR2 KMT2D HIVEP1	3.83e-04	85	81	4	int:PAX2
Interaction	IRF4 interactions	NCOR2 KMT2D FBRS PRDM1	3.83e-04	85	81	4	int:IRF4
Interaction	FXR1 interactions	NCOR2 HIVEP1 UBAP2 ATN1 EIF4ENIF1 SMG7 OTUD4 INAVA BHLHE40 PRRC2A	3.84e-04	679	81	10	int:FXR1
Interaction	STXBP4 interactions	LATS1 LATS2 ATN1 NPAS1	4.00e-04	86	81	4	int:STXBP4
Interaction	SOX6 interactions	ZNF703 NCOR2 FBRS MECOM PRRC2A	4.28e-04	157	81	5	int:SOX6
Interaction	RBPMS interactions	HIVEP1 UBAP2 ATN1 DMRTB1 BHLHE40 CCNK TBX6	4.36e-04	340	81	7	int:RBPMS
Interaction	PRMT2 interactions	SETD1A KRBA1 DMRTB1 PRRC2A	4.96e-04	91	81	4	int:PRMT2
Interaction	SOX10 interactions	NCOR2 HHEX KMT2D HIVEP1	5.17e-04	92	81	4	int:SOX10
Interaction	C6orf141 interactions	ZNF703 KRBA1 SMG7 FBXO7	5.17e-04	92	81	4	int:C6orf141
Interaction	HCFC2 interactions	SETD1A KMT2D ATN1 RERE	5.17e-04	92	81	4	int:HCFC2
Interaction	TLE4 interactions	SMG7 TLE4 TBX20 PRDM1	5.17e-04	92	81	4	int:TLE4
Interaction	RBFOX1 interactions	ATN1 DMRTB1 BHLHE40 PRRC2A	5.17e-04	92	81	4	int:RBFOX1
Interaction	CNOT6L interactions	EIF4ENIF1 SMG7 DCC PRRC2A	5.39e-04	93	81	4	int:CNOT6L
Interaction	RERE interactions	SETD1A ATN1 RERE PRRC2A	5.39e-04	93	81	4	int:RERE
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SETD1A KMT2D MECOM	1.26e-04	34	52	3	487
GeneFamily	HOXL subclass homeoboxes	HOXB3 GSX1 EVX1	4.49e-04	52	52	3	518
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	MECOM PRDM1	1.07e-03	17	52	2	1197
GeneFamily	T-boxes	TBX20 TBX6	1.21e-03	18	52	2	766
GeneFamily	Ataxins\|Trinucleotide repeat containing	NCOR2 KMT2D	2.33e-03	25	52	2	775
GeneFamily	Basic helix-loop-helix proteins	LYL1 BHLHE40 NPAS1	3.90e-03	110	52	3	420
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	HIVEP1 ZBTB22 MECOM ZNF683 ZFPM1 GLIS1 PRDM1	4.27e-03	718	52	7	28
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	PKD1 PKD1L2	6.19e-03	41	52	2	1298
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	NCOR2 RERE	1.02e-02	53	52	2	532
Coexpression	GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	SRRT SETD1A KMT2D ATN1 SMG7 PPRC1 INTS15 PRRC2A	9.99e-06	338	81	8	M17094
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF703 NCOR2 ATN1 INAVA PRRC2A NOTCH1	1.33e-06	186	83	6	bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF703 NCOR2 ATN1 INAVA PRRC2A NOTCH1	1.46e-06	189	83	6	965e0e388251e7318f8b463816dc96ccb4658677
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZNF703 IGF2BP2 THPO BHLHE40 ALOX12B	6.49e-06	140	83	5	7cc891d676555609add6fc7880735d948a2ad801
ToppCell	10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-HSC/MPP\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	HOXB3 HHEX MECOM ZNF683 NPAS1	1.81e-05	173	83	5	34357f0e22c4b6d84582492c82c1ea733ca8477d
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGF2BP2 THPO NFE2 DMRTB1 NR5A1	1.91e-05	175	83	5	9a96794df049d8228fea57c1584c160191d36b56
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GSX1 THPO EVX1 INAVA	2.44e-05	90	83	4	3817a5b0235e632d976ea565175bdbebbd959bf0
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P3\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GSX1 SOX30 DMRTB1 INAVA	2.44e-05	90	83	4	a0baaf2b3cf07d457f0d242fc213689cba6fd449
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	GSX1 THPO EVX1 INAVA	2.44e-05	90	83	4	a528f5dcee1a356dea89ff2588d2e0f276f2d5fc
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P3-Tnr\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GSX1 SOX30 DMRTB1 INAVA	2.44e-05	90	83	4	ab4b08c6ac8695b38f841c0ecf2bb2c032111d04
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SYNDIG1L CDH24 NHS MYO16 NPAS1	2.49e-05	185	83	5	79cff4f3c6ae8e5ea60e8eae082b9275f2679ee9
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	HHEX LYL1 BHLHE40 PCDH1 PRDM1	2.62e-05	187	83	5	29b2e2be26a9d72b154760e47acf61cfe2f45fa7
ToppCell	PCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating1_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	HHEX LYL1 BHLHE40 PCDH1 NOTCH1	3.05e-05	193	83	5	643f992dbce639e7d147924d8b8f455fcebf215a
ToppCell	Megakaryocytic-erythropoietic-Erythro-cells-Basophilic_Erythroblast\|World / Lineage, cell class and subclass	IGF2BP2 NFE2 HYAL3 MECOM LYL1	3.13e-05	194	83	5	f054d78429364622d402ce1d9bf6ad13a1a1bf7e
ToppCell	PCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating1_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	HHEX LYL1 BHLHE40 PCDH1 NOTCH1	3.29e-05	196	83	5	b826dce5b3daa8eb3d4a530b9564de58d9ce3767
Drug	Sulfabenzamide [127-71-9]; Up 200; 14.4uM; PC3; HT_HG-U133A	HOXB3 LATS1 ATN1 SMG7 MORN1 RERE DCC NPAS1	5.51e-07	199	81	8	6634_UP
Drug	Cefsulodin sodium salt [52152-93-9]; Down 200; 7.2uM; PC3; HT_HG-U133A	SETD1A NCOR2 SMG7 FBRS RERE NOTCH1 BAHCC1	5.77e-06	193	81	7	4067_DN
Disease	dentatorubral-pallidoluysian atrophy (implicated_via_orthology)	ATN1 RERE	7.82e-06	2	83	2	DOID:0060162 (implicated_via_orthology)
Disease	mean reticulocyte volume	SETD1A IGF2BP2 PPRC1 NFE2 FBXO7 OTUD4 NR5A1 ZFPM1 LYL1 MYO16 TBX6	1.47e-05	799	83	11	EFO_0010701
Disease	Cerebral Astrocytoma	LATS1 LATS2 NOTCH1	4.72e-05	25	83	3	C0750935
Disease	Intracranial Astrocytoma	LATS1 LATS2 NOTCH1	4.72e-05	25	83	3	C0750936
Disease	Pilocytic Astrocytoma	LATS1 LATS2 NOTCH1	4.72e-05	25	83	3	C0334583
Disease	Astrocytoma	LATS1 LATS2 NOTCH1	4.72e-05	25	83	3	C0004114
Disease	Juvenile Pilocytic Astrocytoma	LATS1 LATS2 NOTCH1	4.72e-05	25	83	3	C0280783
Disease	Diffuse Astrocytoma	LATS1 LATS2 NOTCH1	4.72e-05	25	83	3	C0280785
Disease	Grade I Astrocytoma	LATS1 LATS2 NOTCH1	4.72e-05	25	83	3	C1704230
Disease	Subependymal Giant Cell Astrocytoma	LATS1 LATS2 NOTCH1	4.72e-05	25	83	3	C0205768
Disease	Mixed oligoastrocytoma	LATS1 LATS2 NOTCH1	4.72e-05	25	83	3	C0547065
Disease	Childhood Cerebral Astrocytoma	LATS1 LATS2 NOTCH1	4.72e-05	25	83	3	C0338070
Disease	Gemistocytic astrocytoma	LATS1 LATS2 NOTCH1	5.32e-05	26	83	3	C0334581
Disease	Protoplasmic astrocytoma	LATS1 LATS2 NOTCH1	5.32e-05	26	83	3	C0334580
Disease	Fibrillary Astrocytoma	LATS1 LATS2 NOTCH1	5.32e-05	26	83	3	C0334582
Disease	Anaplastic astrocytoma	LATS1 LATS2 NOTCH1	5.98e-05	27	83	3	C0334579
Disease	Lymphoid leukemia	MECOM LYL1	2.16e-04	8	83	2	C0023448
Disease	benign neoplasm (implicated_via_orthology)	LATS1 LATS2	2.16e-04	8	83	2	DOID:0060072 (implicated_via_orthology)
Disease	household income	MST1R CASC3 TLE4 DCC LYL1 PCDH1	2.21e-04	304	83	6	EFO_0009695
Disease	mean corpuscular hemoglobin concentration	KRBA1 SLC2A4RG ATN1 MORN1 NFE2 FBXO7 OTUD4 MECOM ZFPM1 MYO16 TBX6	2.65e-04	1105	83	11	EFO_0004528
Disease	nicotine use	DMRTB1 GLIS1	2.78e-04	9	83	2	EFO_0005430
Disease	platelet crit	KRBA1 IGF2BP2 THPO TLE4 MAP3K14 OTUD4 MECOM ZFPM1 RERE LYL1	3.37e-04	952	83	10	EFO_0007985
Disease	forced expiratory volume	SETD1A SYNDIG1L NCOR2 HOXB3 IGF2BP2 SLC2A4RG OTUD4 MECOM DCC	3.75e-04	789	83	9	EFO_0004314
Disease	kidney cancer (implicated_via_orthology)	LATS1 LATS2	4.23e-04	11	83	2	DOID:263 (implicated_via_orthology)
Disease	intracranial aneurysm (is_implicated_in)	KMT2D PKD1	5.07e-04	12	83	2	DOID:10941 (is_implicated_in)
Disease	Connective Tissue Diseases	PKD1 NOTCH1	5.98e-04	13	83	2	C0009782
Disease	autosomal dominant polycystic kidney disease (implicated_via_orthology)	LATS1 PKD1	6.96e-04	14	83	2	DOID:898 (implicated_via_orthology)
Disease	eosinophil count	NCOR2 HHEX HIVEP1 NFE2 MAP3K14 SLC35E1 ZFPM1 RERE MYO16 NOTCH1 BAHCC1 TBX6	9.07e-04	1488	83	12	EFO_0004842
Disease	bipolar disorder, sex interaction measurement	TLE4 ADGRB1	1.16e-03	18	83	2	EFO_0008343, MONDO_0004985
Disease	noggin measurement	HHEX NFE2	1.16e-03	18	83	2	EFO_0021995
Disease	feeling miserable measurement	MST1R RERE DCC	1.45e-03	79	83	3	EFO_0009598
Disease	Glioblastoma	SRRT BHLHE40 NOTCH1	1.45e-03	79	83	3	C0017636
Disease	ankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis	SETD1A HHEX INAVA NOTCH1 PRDM1	1.48e-03	295	83	5	EFO_0000384, EFO_0000676, EFO_0000729, EFO_0003898, EFO_0004268
Disease	Ovarian Failure, Premature	EIF4ENIF1 NR5A1	1.59e-03	21	83	2	C0085215
Disease	Giant Cell Glioblastoma	SRRT BHLHE40 NOTCH1	1.74e-03	84	83	3	C0334588
Disease	Splenomegaly	MECOM NOTCH1	1.74e-03	22	83	2	C0038002
Disease	balding measurement	NCOR2 TLE4 MAP3K14 INAVA RERE BHLHE40 GLIS1 PRDM1	1.74e-03	792	83	8	EFO_0007825
Disease	colorectal cancer, hormone replacement therapy	IGF2BP2 HIVEP1 MYO16	1.98e-03	88	83	3	EFO_0003961, MONDO_0005575
Disease	congenital heart disease (is_implicated_in)	TBX20 NOTCH1	2.07e-03	24	83	2	DOID:1682 (is_implicated_in)
Disease	beta-aminoisobutyric acid measurement	BHLHE40 PCDH1	2.07e-03	24	83	2	EFO_0010464

Protein segments in the cluster

Peptide	Gene	Start	Entry
KLPPSLYPPHFYPNP	ERFL	241	A0A1W2PQ73
PKLGRPLPSPSYVHP	BAHCC1	2266	Q9P281
IHYPLPLPYQGKPDP	CCDC61	131	Q9Y6R9
SPRYPGGPLPDFPNH	ADGRB1	1291	O14514
PHQPPFCLPFYLIPP	BHLHE40	316	O14503
AGGLPYPFPSHLPLP	EVX1	266	P49640
LSQGPARPYHPPPLF	ATN1	151	P54259
FQAPPGAPPPHPQLY	ATN1	206	P54259
LGSLRPYPPGPAHLP	ATN1	536	P54259
LPPAYGPPAHLPYHP	CCNK	461	O75909
PFLGPVPIAPPFFPH	OTUD4	846	Q01804
LPPGFYPHIHTPPLG	INTS15	401	Q96N11
PGPALPEAFYPPLGL	NPAS1	561	Q99742
FPGLFPSGLYHRPPL	MECOM	491	Q03112
LLGPPPPGYHPFLFL	MORN1	371	Q5T089
DPSAFSYAPPGHPLP	NCOR2	1071	Q9Y618
GYPHPQFTLRPVPFP	DCC	1271	P43146
GLAYPPLPLHEGPPR	KIDINS220	1076	Q9ULH0
PLPLHEGPPRAPSGY	KIDINS220	1081	Q9ULH0
PGYLLTPPPHPDLGA	KRBA1	311	A5PL33
PHGYLSDVASPPLLP	NOTCH1	2206	P46531
RPGPPTPAAAHSIPY	MAVS	116	Q7Z434
NYQGPPPPYPKHLLH	LATS1	551	O95835
GLAFPPPAAGLYVPH	LATS2	301	Q9NRM7
GPPPAPYRPCAHLAF	MYO16	1581	Q9Y6X6
PLYAPTPLLQPAHPT	HHEX	16	Q03014
NPPIFPLGPYHATVP	CDH24	146	Q86UP0
PSGLLAHAFPPGPNY	MMP13	181	P45452
PGDSPRIHLPLNYPP	PCDH1	946	Q08174
HPVPPGLPLFLPYYI	PDCD2L	176	Q9BRP1
PLYPAPLSQPPHFQG	FKBP15	486	Q5T1M5
LYELHAAGAPPPPPP	ZFPM1	746	Q8IX07
EQPHGLYLLPPGAPF	GHDC	306	Q8N2G8
PPLFPYAVPPPHALH	GSX1	26	Q9H4S2
GPRGAPPAAPYHPFT	IGF2BP2	386	Q9Y6M1
YNELLPPAFHLPLPG	MMACHC	31	Q9Y4U1
PPAFHLPLPGPTLAF	MMACHC	36	Q9Y4U1
VAPLPGHLLGPDPYA	PKD1L2	1896	Q7Z442
PPLHRSPDFLLSYPP	ARHGAP33	1126	O14559
AHPLLYSRLAPPPPP	FBRS	401	Q9HAH7
HPHQTPAPLPNPGLY	CASC3	586	O15234
FPGTPYPEPSKLPHT	GFY	61	I3L273
PGYLSALHFLPPPPP	DMRTB1	286	Q96MA1
TIPFYPNPLHPRPFP	FBXO7	421	Q9Y3I1
LFPSIYLPPRLPPAH	HYAL3	241	O43820
PLPPPAGPSLYGLNH	HOXB3	361	P14651
PGLPSYVHIPSYRPP	ALOX12B	151	O75342
PHPFLNSVYIGPAGP	LYL1	106	P12980
LFGPHQQGLPPPYPL	GLIS1	156	Q8NBF1
SYAPGLPPPHPTTKA	DVL1P1	611	P54792
HHPKLLLPPGYFPAG	INAVA	506	Q3KP66
YPHVSPSGYPCLPPP	PPRC1	926	Q5VV67
PALDSYFHPPGTPAP	IL17RC	761	Q8NAC3
PAPGHPGPRAPYLSA	PKD1	731	P98161
GRPVTFYPHPLPSPG	PKD1	1141	P98161
QDGGPLPLPTHPFPY	MAP3K14	246	Q99558
HPDSGFPLPPPPYEL	NFE2	71	Q16621
PAHLHGPYPYPETPP	SYNDIG1L	16	A6NDD5
QKLPPPLFPHPYGFP	SKOR1	386	P84550
PDYVLPPSLHGPEPK	NR5A1	136	Q13285
LSIAAPPLPAYPPAH	NHS	256	Q6T4R5
FIPIHHPGAFPPLPS	SMG7	646	Q92540
LDFYPPGVHPSGLVP	PRRC2A	741	P48634
LHPYRSQPLYLPPGP	PRRC2A	1871	P48634
HLAAHAPYLMFPPPP	SHOX	231	O15266
LLLLYVHSDPPSPPP	SPATA31E1	81	Q6ZUB1
LGSYPGYAPLPHLPP	PRDM1	386	O75626
GYAPLPHLPPAFIPS	PRDM1	391	O75626
ARFPYPPGTLPNPLL	RERE	1466	Q9P2R6
HPSSGPLLPPRFYPR	SLC35E1	96	Q96K37
VLLPPSSPGPPHRVY	PROB1	916	E7EW31
PYLASLPLGYPPHQP	SETD1A	616	O15047
LPLGYPPHQPAYLLP	SETD1A	621	O15047
HFPPGFQPIPCKPLF	SRP68	576	Q9UHB9
VYQPPPLGHPATLFG	SOX30	591	O94993
ILPPGLTPGLPYPHQ	SRRT	776	Q9BXP5
GQPFYPLPAASHPLL	EIF4ENIF1	871	Q9NRA8
APGYAPPPFLHILPA	UBAP2	1056	Q5T6F2
VSPYKPGHSVFPLPP	ZNF703	296	Q9H7S9
PSPPLPPEAAHFLFG	SLC2A4RG	171	Q9NR83
VPCPYPTPFGIVPHA	TLE4	366	Q04727
PGPALSPSVPLHYLP	RNF44	241	Q7L0R7
SGYPAAPPAVPFAPH	TBX6	396	O95947
PFAPHFLQGGPFPLP	TBX6	406	O95947
ATPIPHPIQGSLPPY	TBX20	376	Q9UMR3
PPHLPPYLAPASQVG	WNK2	756	Q9Y3S1
GFTLPGFRFLPPPHP	MST1R	851	Q04912
GYSAVPANIIPPPHP	HIVEP1	846	P15822
SYAPSHPPRPLLPLD	ZBTB22	406	O15209
AFYPGYPLLLPPPHL	ZNF683	191	Q8IZ20
PTHPPTGQYTLFPLP	THPO	296	P40225
LPPPAPDGSLPYLSH	KMT2D	2616	O14686