Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

TTF2 CHD8 CHD3 INO80 SMARCA2 SMARCA4

5.09e-07371636GO:0140658
GeneOntologyMolecularFunctioncytoskeletal protein binding

FKBP15 TRPM7 SPTA1 PPP1R9A DPYSL4 EPS8L1 INO80 EPB41L4A CLSTN1 DYSF JAKMIP2 FARP2 TUBGCP6 TLNRD1 SLC8A1 PDLIM3 MYH14 SIPA1L1 MYO3B SYNE2 MAST1 KIF5C CROCC

3.08e-05109916323GO:0008092
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

TTF2 CHD8 CHD3 INO80 SMARCA2 MLH1 SMARCA4

8.35e-051271637GO:0008094
GeneOntologyMolecularFunctionactin binding

FKBP15 TRPM7 SPTA1 PPP1R9A EPS8L1 INO80 TLNRD1 PDLIM3 MYH14 SIPA1L1 MYO3B SYNE2 CROCC

1.59e-0447916313GO:0003779
GeneOntologyMolecularFunctionhistone binding

IPO7 ING1 CHD8 CHD3 INO80 SMARCA2 SMARCA4 KMT2A WDTC1

3.37e-042651639GO:0042393
GeneOntologyMolecularFunctionsynaptic receptor adaptor activity

SHANK1 SHANK2

3.93e-0441632GO:0030160
GeneOntologyMolecularFunctionATP-dependent activity

ATP8B3 TTF2 ATP7A CHD8 CHD3 INO80 MDN1 MYH14 MYO3B SMARCA2 MLH1 SMARCA4 KIF5C DNAH8

5.25e-0461416314GO:0140657
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL6A2 COL11A1 COL13A1 COL6A6

5.35e-04461634GO:0030020
GeneOntologyBiologicalProcessactin filament-based process

SHANK1 TRPM7 SPTA1 PPP1R9A MYOM3 EPB41L4A ARHGEF17 FARP2 PLEK2 PDLIM3 MYH14 PPM1F TESK2 SIPA1L1 MYO3B SYNE2 FZD10 ARHGAP25 PRKCQ BAIAP2 NOS1

9.86e-0691216221GO:0030029
GeneOntologyBiologicalProcessactin cytoskeleton organization

SHANK1 TRPM7 SPTA1 PPP1R9A MYOM3 EPB41L4A ARHGEF17 FARP2 PLEK2 PDLIM3 MYH14 PPM1F TESK2 SIPA1L1 MYO3B FZD10 ARHGAP25 PRKCQ BAIAP2

1.86e-0580316219GO:0030036
GeneOntologyCellularComponentcell leading edge

ERBB2 ATP7A TRPM7 PPP1R9A EPS8L1 GRIN1 PLXND1 DYSF TUBG1 PLEK2 SYNE2 BAIAP2 MCF2L GABRA4

3.41e-0550016114GO:0031252
GeneOntologyCellularComponentdendritic spine

SHANK1 PPP1R9A GRIN1 CLSTN1 SLC8A1 SHANK2 SIPA1L1 BAIAP2 NOS1

1.12e-042421619GO:0043197
GeneOntologyCellularComponentneuron spine

SHANK1 PPP1R9A GRIN1 CLSTN1 SLC8A1 SHANK2 SIPA1L1 BAIAP2 NOS1

1.30e-042471619GO:0044309
GeneOntologyCellularComponentpostsynaptic specialization

SHANK1 ATP7A PPP1R9A GRIN1 CLSTN1 CRHR1 CHRND SLC8A1 SHANK2 SIPA1L1 BAIAP2 NOS1 GABRA4

1.46e-0450316113GO:0099572
GeneOntologyCellularComponentgamma-tubulin complex

TUBG2 TUBG1 TUBGCP6

5.39e-04211613GO:0000930
GeneOntologyCellularComponentlamellipodium membrane

PLXND1 PLEK2 SYNE2

6.20e-04221613GO:0031258
GeneOntologyCellularComponentpostsynaptic density

SHANK1 ATP7A PPP1R9A GRIN1 CLSTN1 CRHR1 SLC8A1 SHANK2 SIPA1L1 BAIAP2 NOS1

7.66e-0445116111GO:0014069
GeneOntologyCellularComponentdendrite

SHANK1 ATP7A PPP1R9A GRIN1 CLSTN1 CRHR1 SLC8A1 SHANK2 SV2A SIPA1L1 MAST1 RABGEF1 KIF5C BAIAP2 NOS1 GABRA4

9.87e-0485816116GO:0030425
GeneOntologyCellularComponentdendritic tree

SHANK1 ATP7A PPP1R9A GRIN1 CLSTN1 CRHR1 SLC8A1 SHANK2 SV2A SIPA1L1 MAST1 RABGEF1 KIF5C BAIAP2 NOS1 GABRA4

1.01e-0386016116GO:0097447
GeneOntologyCellularComponentasymmetric synapse

SHANK1 ATP7A PPP1R9A GRIN1 CLSTN1 CRHR1 SLC8A1 SHANK2 SIPA1L1 BAIAP2 NOS1

1.21e-0347716111GO:0032279
GeneOntologyCellularComponentpostsynaptic membrane

SHANK1 ERBB2 COL13A1 GRIN1 CLSTN1 CRHR1 CHRND SLC8A1 SHANK2 GABRA4

1.21e-0340516110GO:0045211
GeneOntologyCellularComponentleading edge membrane

ERBB2 EPS8L1 GRIN1 PLXND1 PLEK2 SYNE2 GABRA4

1.24e-032101617GO:0031256
GeneOntologyCellularComponentfibrillar center

RERG RREB1 UTP15 RPS6KA6 SMARCA4 PLRG1

1.34e-031561616GO:0001650
HumanPhenoAbnormality of the shoulder girdle musculature

COL6A2 TBX3 COL13A1 MATR3 PLXND1 DYSF CHRND PTPN11 SYNE2

1.82e-05149539HP:0001435
HumanPhenoAbnormal shoulder morphology

COL6A2 TBX3 COL13A1 ATP7A MATR3 PLXND1 DYSF CHRND PTPN11 SYNE2 TBL2

3.34e-052465311HP:0003043
MousePhenoabnormal maternal behavior

SHANK1 ING1 CORT SPTA1 GRIN1 SHANK2 NEK8 NOS1

1.23e-051151318MP:0008779
MousePhenoabnormal maternal nurturing

SHANK1 ING1 CORT SPTA1 GRIN1 SHANK2 NEK8

5.74e-051051317MP:0001386
MousePhenodouble outlet right ventricle

DNAAF4 MATR3 ERMP1 PLXND1 PTPN11 ADAMTS6 NEK8 SMARCA4

8.28e-051501318MP:0000284
MousePhenoabnormal interventricular septum muscular part morphology

DNAAF4 MATR3 XPNPEP1 ADAMTS6 SMARCA4 BAIAP2

9.59e-05791316MP:0010498
MousePhenoabnormal heart ventricle wall morphology

ERBB2 RREB1 ARHGEF17 ANKLE2 SLC8A1 PTPN11 PDLIM3 ADAMTS6 CTCF BAIAP2 NOS1

1.06e-0429613111MP:0031532
MousePhenoabnormal parental behavior

SHANK1 ING1 CORT SPTA1 GRIN1 SHANK2 NEK8 NOS1

1.30e-041601318MP:0002068
MousePhenoatrioventricular septal defect

DNAAF4 PLXND1 PTPN11 ADAMTS6 NEK8 SMARCA4

1.35e-04841316MP:0010412
MousePhenoabnormal heart ventricle morphology

TBX3 ERBB2 COL11A1 DNAAF4 MATR3 XPNPEP1 PLXND1 RREB1 ARHGEF17 ANKLE2 SLC8A1 PTPN11 PDLIM3 ADAMTS6 CTCF NEK8 SMARCA4 BAIAP2 NOS1

1.46e-0479313119MP:0005294
MousePhenoabnormal atrioventricular septum morphology

DNAAF4 PLXND1 PTPN11 ADAMTS6 NEK8 SMARCA4

1.64e-04871316MP:0010592
DomainSNF2_N

TTF2 CHD8 CHD3 INO80 SMARCA2 SMARCA4

2.52e-07321586IPR000330
DomainSNF2_N

TTF2 CHD8 CHD3 INO80 SMARCA2 SMARCA4

2.52e-07321586PF00176
DomainBRK

CHD8 SMARCA2 SMARCA4

1.17e-0561583SM00592
DomainBRK_domain

CHD8 SMARCA2 SMARCA4

1.17e-0561583IPR006576
DomainBRK

CHD8 SMARCA2 SMARCA4

1.17e-0561583PF07533
DomainGln-Leu-Gln_QLQ

SMARCA2 SMARCA4

7.11e-0521582IPR014978
DomainSnAC

SMARCA2 SMARCA4

7.11e-0521582PF14619
DomainQLQ

SMARCA2 SMARCA4

7.11e-0521582SM00951
DomainQLQ

SMARCA2 SMARCA4

7.11e-0521582PS51666
DomainSnAC

SMARCA2 SMARCA4

7.11e-0521582SM01314
DomainSnAC

SMARCA2 SMARCA4

7.11e-0521582IPR029295
DomainQLQ

SMARCA2 SMARCA4

7.11e-0521582PF08880
DomainGamma_tubulin

TUBG2 TUBG1

7.11e-0521582IPR002454
DomainPDZ

SHANK1 PPP1R9A SHANK2 PDLIM3 SIPA1L1 MAST1 NOS1

1.99e-041411587PF00595
DomainPDZ

SHANK1 PPP1R9A SHANK2 PDLIM3 SIPA1L1 MAST1 NOS1

2.68e-041481587SM00228
Domain-

SHANK1 PPP1R9A SHANK2 PDLIM3 SIPA1L1 MAST1 NOS1

2.91e-0415015872.30.42.10
DomainHelicase_C

TTF2 CHD8 CHD3 INO80 SMARCA2 SMARCA4

2.98e-041071586PF00271
DomainHELICc

TTF2 CHD8 CHD3 INO80 SMARCA2 SMARCA4

2.98e-041071586SM00490
DomainPDZ

SHANK1 PPP1R9A SHANK2 PDLIM3 SIPA1L1 MAST1 NOS1

3.03e-041511587PS50106
DomainHelicase_C

TTF2 CHD8 CHD3 INO80 SMARCA2 SMARCA4

3.13e-041081586IPR001650
DomainPDZ

SHANK1 PPP1R9A SHANK2 PDLIM3 SIPA1L1 MAST1 NOS1

3.15e-041521587IPR001478
DomainHELICASE_CTER

TTF2 CHD8 CHD3 INO80 SMARCA2 SMARCA4

3.29e-041091586PS51194
DomainHELICASE_ATP_BIND_1

TTF2 CHD8 CHD3 INO80 SMARCA2 SMARCA4

3.29e-041091586PS51192
DomainDEXDc

TTF2 CHD8 CHD3 INO80 SMARCA2 SMARCA4

3.29e-041091586SM00487
DomainHelicase_ATP-bd

TTF2 CHD8 CHD3 INO80 SMARCA2 SMARCA4

3.46e-041101586IPR014001
DomainHSA

SMARCA2 SMARCA4

4.22e-0441582SM00573
DomainHSA

SMARCA2 SMARCA4

4.22e-0441582PS51204
DomainHSA_dom

SMARCA2 SMARCA4

4.22e-0441582IPR014012
DomainHSA

SMARCA2 SMARCA4

4.22e-0441582PF07529
DomainSH3_2

SHANK1 MACC1 SHANK2 BAIAP2 MCF2L

8.16e-04861585PF07653
DomainSH3_2

SHANK1 MACC1 SHANK2 BAIAP2 MCF2L

8.16e-04861585IPR011511
DomainSpectrin

SPTA1 SYNE2 MCF2L

9.29e-04231583PF00435
DomainPH_dom-like

ARHGEF28 EPS8L1 PLEKHA6 EPB41L4A ARHGEF17 FARP2 PLEK2 MTMR3 ARHGAP25 MCF2L PLEKHA7

1.02e-0342615811IPR011993
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

COL6A2 ERBB2 ARHGEF28 COL6A6 SPTA1 DPYSL4 GRIN1 PLXND1 FARP2 PTPN11 PRKCQ

1.62e-0526112211MM15676
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SHANK1 FKBP15 NES USP28 MATR3 PPP1R9A DPYSL4 CHD8 GRIN1 HUWE1 JAKMIP2 ITIH4 MDN1 SHANK2 UBR5 CTCF SIPA1L1 SYNE2 SMARCA4 RABGEF1 KIF5C BAIAP2 NOS1 UNC79 CEP170B GOLGA3 SH3BP5

1.00e-139631642728671696
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

MUC16 CHD3 XPNPEP1 HUWE1 MDN1 NEK8 SYNE2 DECR2 UNC79 HYDIN

9.16e-091701641023314748
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SMG1 ERBB2 EMC1 USP28 CEP162 MATR3 CHD8 ERMP1 PLXND1 INO80 ANKLE2 CWC22 TUBGCP6 PPM1F ANKS3

3.67e-085291641514621295
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SHANK1 NES SPTA1 MATR3 PPP1R9A DPYSL4 CHD3 GRIN1 PLEKHA6 ARHGEF17 SHANK2 MYH14 SV2A SIPA1L1 SMARCA4 MAST1 KMT2A KIF5C BAIAP2 CROCC PLEKHA7 NOS1 CEP170B GOLGA3

7.18e-0814311642437142655
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

SMG1 FBLN7 ERBB2 MUC16 PTPN11 SHANK2 UTP15 PPM1F NEK8 MTMR3 RABGEF1 PLEKHA7 DNAH8

1.14e-074201641328065597
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NES ERBB2 EMC1 ARHGEF28 TRPM7 CEP162 MATR3 ARHGEF17 MDN1 TESK2 SIPA1L1 SYNE2 KMT2A RABGEF1 KIF5C BAIAP2 PLEKHA7 CEP170B

1.52e-078611641836931259
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

MACC1 EMC1 ZNF652 PPP1R9A CHD8 ERMP1 INO80 FARP2 MED15 MDN1 SHANK2 UTP15 CTCF SIPA1L1 SMARCA2 MLH1 KMT2A DECR2 BAIAP2 CROCC PLEKHA7 TBL2 CEP170B STOM

1.64e-0714971642431527615
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

MATR3 CHD8 CHD3 INO80 CWC22 MED15 MDN1 CTCF SMARCA2 SMARCA4 NLRC5 KMT2A BAIAP2 CROCC

2.69e-075331641430554943
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TBX3 ERBB2 CHD8 CHD3 INO80 RREB1 TUBG1 ITIH4 TUBGCP6 THADA UBR5 CTCF SV2A SIPA1L1 SMARCA2 MLH1 SMARCA4 ANKS3 CEP170B WDTC1

3.48e-0711161642031753913
Pubmed

Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses.

SHANK1 GRIN1 SHANK2 BAIAP2

4.60e-0714164421795692
Pubmed

The essential role of centrosomal NDE1 in human cerebral cortex neurogenesis.

NES TUBG2 TUBG1

1.02e-065164321529752
Pubmed

WDR62 is associated with the spindle pole and is mutated in human microcephaly.

NES TUBG2 TUBG1

1.02e-065164320890279
Pubmed

The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42.

SHANK1 SHANK2 BAIAP2

1.02e-065164312504591
Pubmed

Insulin receptor substrate of 53 kDa links postsynaptic shank to PSD-95.

SHANK1 GRIN1 BAIAP2

1.02e-065164315255944
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

COL6A2 PRTG ERBB2 COL13A1 ZNF652 CYBC1 CC2D1B CHD8 ERMP1 WAC TUBGCP6 TLNRD1 PTPN11 VPS13A MLH1 RABGEF1 PLEKHA7 CEP170B CAVIN2 SH3BP5

1.30e-0612151642015146197
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

FKBP15 IPO7 USP28 MATR3 CHD8 CHD3 PSME2 INO80 MED15 GTF2E1 PTPN11 MDN1 UBR5 CTCF SMARCA2 SMARCA4 KMT2A PLRG1

1.60e-0610141641832416067
Pubmed

CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors.

TUBG2 TUBG1 CROCC

2.04e-066164336334595
Pubmed

DOCK7 interacts with TACC3 to regulate interkinetic nuclear migration and cortical neurogenesis.

NES TUBG2 TUBG1

2.04e-066164322842144
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SMG1 COL6A2 TBX3 EMC1 ARHGEF28 CC2D1B CHD8 CHD3 CLSTN1 CWC22 FARP2 MLH1 KMT2A PLRG1

2.79e-066501641438777146
Pubmed

Defining the membrane proteome of NK cells.

DCAKD FKBP15 ATP7A IPO7 MATR3 AGPAT3 ERMP1 PSME2 HUWE1 ANKLE2 MED15 TUBGCP6 MDN1 UBR5 MYH14 MLH1 SMARCA4 GOLGA3 STOM

2.89e-0611681641919946888
Pubmed

HIV-1 Vpr hijacks EDD-DYRK2-DDB1DCAF1 to disrupt centrosome homeostasis.

TUBG2 TUBG1 UBR5

3.55e-067164329724823
Pubmed

Asymmetric segregation of the double-stranded RNA binding protein Staufen2 during mammalian neural stem cell divisions promotes lineage progression.

NES TUBG2 TUBG1

3.55e-067164322902295
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FKBP15 PPP1R9A ARHGEF17 UBR5 SV2A SIPA1L1 MTMR3 MAST1 MCF2L CROCC CEP170B

4.09e-064071641112693553
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

DCAKD FKBP15 DNAAF4 AGPAT3 PPP1R11 RREB1 ANKLE2 TUBG1 MED15 THADA NEK8 TESK2 SIPA1L1 RABGEF1 KIF5C BAIAP2 PLEKHA7 ANKS3 STOM WDTC1

4.57e-0613211642027173435
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ERBB2 MYOM3 CHD8 PLXND1 INO80 HUWE1 DYSF TUBG1 TLNRD1 THADA TKFC MDN1 SHANK2 NEK8 MTMR3 NLRC5 MCF2L CEP170B

5.27e-0611051641835748872
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

ING1 USP28 CHD8 CHD3 WAC MED15 SMARCA2 SMARCA4 KMT2A

5.60e-06268164933640491
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DCAKD ERBB2 PPP1R9A AGPAT3 CHD3 HUWE1 FARP2 THADA USF3 SHANK2 MYH14 SMARCA2 NLRC5 MAST1 KIF5C BAIAP2 MCF2L CROCC POLK ZMAT1 CEP170B

7.68e-0614891642128611215
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

DNAAF4 ERMP1 PLXND1 ADAMTS6 NEK8 SMARCA4

8.29e-06100164625807483
Pubmed

Direct binding of NuMA to tubulin is mediated by a novel sequence motif in the tail domain that bundles and stabilizes microtubules.

TUBG2 TUBG1 TUBGCP6

8.47e-069164311956313
Pubmed

Dynamic changes of NuMA during the cell cycle and possible appearance of a truncated form of NuMA during apoptosis.

TUBG2 TUBG1 TUBGCP6

8.47e-06916438838651
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

SMG1 DDAH2 ERBB2 EMC1 ATP7A PPP1R9A AGPAT3 PLEKHA6 THADA SHANK2 UBR5 BAIAP2 PLEKHA7 CAVIN2

8.77e-067191641435337019
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

CEP162 ZNF652 PLEKHA6 SYNE2 VPS13A MAST1

9.29e-06102164610231032
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

TTF2 FKBP15 CEP162 PPP1R9A UBR5 SIPA1L1 MTMR3 RABGEF1 BAIAP2 PLEKHA7 CEP170B

9.67e-064461641124255178
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

TTF2 FKBP15 USP28 MATR3 DPYSL4 CHD3 PSME2 WAC GTF2E1 PTPN11 PDLIM3 CTCF MLH1 SMARCA4 KMT2A PLRG1

9.77e-069341641633916271
Pubmed

The functional interactome landscape of the human histone deacetylase family.

TTF2 ING1 CHD3 HUWE1 RREB1 MDN1 UBR5 SYNE2 CROCC

1.03e-05289164923752268
Pubmed

The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity.

SHANK1 GRIN1 SHANK2 BAIAP2

1.03e-0529164419208628
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

DCAKD EMC1 IPO7 CEP162 PPP1R9A PPP1R11 HUWE1 ANKLE2 GTF2E1 PTPN11 PPM1F SYNE2 VPS13A MTMR3 MLH1 BAIAP2 PLEKHA7

1.04e-0510491641727880917
Pubmed

A protein interaction landscape of breast cancer.

TBX3 ERBB2 USP28 MDN1 UBR5 CTCF SMARCA2 MLH1 SMARCA4 PLEKHA7 TBL2 CAVIN2 STOM

1.08e-056341641334591612
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

SMG1 IPO7 MUC16 MED15 MDN1 ADAMTS6 PPM1F SYNE2 VPS13A SMARCA2 MCF2L TBL2 CAVIN2

1.15e-056381641331182584
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

NES IPO7 CHD8 HUWE1 MDN1 UBR5 UTP15 CTCF MYH14 SYNE2 SMARCA2 SMARCA4 KMT2A

1.47e-056531641322586326
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

IPO7 ING1 CHD8 CHD3 HUWE1 DNAAF8 SMARCA4 KMT2A UNC79 PLRG1 HYDIN

1.54e-054691641127634302
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SMG1 MACC1 SPTA1 MATR3 PPP1R9A CC2D1B CHD3 ANKLE2 PLEK2 C4orf17 MDN1 SHANK2 MYH14 SYNE2 VPS13A KMT2A KIF5C MCF2L DNAH8 CAVIN2

1.64e-0514421642035575683
Pubmed

Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes.

CHD3 SMARCA2 SMARCA4

1.65e-0511164310204490
Pubmed

The spatio-temporal and subcellular expression of the candidate Down syndrome gene Mnb/Dyrk1A in the developing mouse brain suggests distinct sequential roles in neuronal development.

NES TUBG2 TUBG1

1.65e-0511164318364031
Pubmed

Gradual centriole maturation associates with the mitotic surveillance pathway in mouse development.

TUBG2 USP28 TUBG1

1.65e-0511164333410253
Pubmed

An RNA-binding protein, Qki5, regulates embryonic neural stem cells through pre-mRNA processing in cell adhesion signaling.

NES TUBG2 TUBG1

1.65e-0511164329021239
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

TTF2 IPO7 CCDC174 ZNF652 CHD8 CHD3 PSME2 RREB1 TUBG1 PRDM2 WAC MED15 UBR5 SMARCA2 SMARCA4 KMT2A PLRG1

1.98e-0511031641734189442
Pubmed

Novel embryonic neuronal migration and proliferation defects in Dcx mutant mice are exacerbated by Lis1 reduction.

NES TUBG2 TUBG1

2.20e-0512164320181597
Pubmed

Augmin deficiency in neural stem cells causes p53-dependent apoptosis and aborts brain development.

NES TUBG2 TUBG1

2.20e-0512164334427181
Pubmed

Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions.

NES TUBG2 TUBG1

2.20e-0512164333326788
Pubmed

Recapitulation of two genomewide association studies on blood pressure and essential hypertension in the Korean population.

TBX3 ZNF652 PLEKHA7

2.20e-0512164320414254
Pubmed

The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.

SMARCA2 SMARCA4

2.21e-05216428670841
Pubmed

Differential expression of alternatively spliced isoforms of neuronal nitric oxide synthase (nNOS) and N-methyl-D-aspartate receptors (NMDAR) in knockout mice deficient in nNOS alpha (nNOS alpha(Delta/Delta) mice).

GRIN1 NOS1

2.21e-052164211146102
Pubmed

Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features.

SMARCA2 SMARCA4

2.21e-052164223163725
Pubmed

Decreased phosphorylation of δ and ε subunits of the acetylcholine receptor coincides with delayed postsynaptic maturation in PKC θ deficient mouse.

CHRND PRKCQ

2.21e-052164220599977
Pubmed

CTCF-dependent chromatin insulator is linked to epigenetic remodeling.

CHD8 CTCF

2.21e-052164216949368
Pubmed

Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development.

SMARCA2 SMARCA4

2.21e-052164223076393
Pubmed

Genetic associations in PLEKHA7 and COL11A1 with primary angle closure glaucoma: a meta-analysis.

COL11A1 PLEKHA7

2.21e-052164225732101
Pubmed

The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.

SMARCA2 SMARCA4

2.21e-052164215576411
Pubmed

Molecular mechanism for SHP2 in promoting HER2-induced signaling and transformation.

ERBB2 PTPN11

2.21e-052164219261604
Pubmed

Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.

SMARCA2 SMARCA4

2.21e-052164215240517
Pubmed

Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type.

SMARCA2 SMARCA4

2.21e-052164226564006
Pubmed

SMARCA4/SMARCA2-deficient Carcinoma of the Esophagus and Gastroesophageal Junction.

SMARCA2 SMARCA4

2.21e-052164233027072
Pubmed

A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.

SMARCA2 SMARCA4

2.21e-052164223872584
Pubmed

Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.

SMARCA2 SMARCA4

2.21e-052164223088494
Pubmed

SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.

SMARCA2 SMARCA4

2.21e-052164220333683
Pubmed

SWI/SNF Complex-deficient Undifferentiated Carcinoma of the Gastrointestinal Tract: Clinicopathologic Study of 30 Cases With an Emphasis on Variable Morphology, Immune Features, and the Prognostic Significance of Different SMARCA4 and SMARCA2 Subunit Deficiencies.

SMARCA2 SMARCA4

2.21e-052164234812766
Pubmed

Targeting of BRM Sensitizes BRG1-Mutant Lung Cancer Cell Lines to Radiotherapy.

SMARCA2 SMARCA4

2.21e-052164230478150
Pubmed

MTOC reorientation occurs during FcgammaR-mediated phagocytosis in macrophages.

TUBG2 TUBG1

2.21e-052164217442887
Pubmed

Association of ADHD and the Protogenin gene in the chromosome 15q21.3 reading disabilities linkage region.

PRTG DNAAF4

2.21e-052164219076634
Pubmed

Assessing acute myeloid leukemia susceptibility in rearrangement-driven patients by DNA breakage at topoisomerase II and CCCTC-binding factor/cohesin binding sites.

CTCF KMT2A

2.21e-052164234405474
Pubmed

The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation.

SMARCA2 SMARCA4

2.21e-052164225808524
Pubmed

Overexpression of γ-tubulin in non-small cell lung cancer.

TUBG2 TUBG1

2.21e-052164222806905
Pubmed

Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation.

SMARCA2 SMARCA4

2.21e-052164219144648
Pubmed

High expression of SMARCA4 or SMARCA2 is frequently associated with an opposite prognosis in cancer.

SMARCA2 SMARCA4

2.21e-052164229391527
Pubmed

Expression of SMARCA2 and SMARCA4 in gastric adenocarcinoma and construction of a nomogram prognostic model.

SMARCA2 SMARCA4

2.21e-052164237634210
Pubmed

Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor.

SMARCA2 SMARCA4

2.21e-05216428208605
Pubmed

Allocation of gamma-tubulin between oocyte cortex and meiotic spindle influences asymmetric cytokinesis in the mouse oocyte.

TUBG2 TUBG1

2.21e-052164217287496
Pubmed

A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes.

SMARCA2 SMARCA4

2.21e-052164211163203
Pubmed

Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes.

SMARCA2 SMARCA4

2.21e-052164212620226
Pubmed

BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo.

SMARCA2 SMARCA4

2.21e-052164227039070
Pubmed

Partial Inactivation of the Chromatin Remodelers SMARCA2 and SMARCA4 in Virus-Infected Cells by Caspase-Mediated Cleavage.

SMARCA2 SMARCA4

2.21e-052164229848589
Pubmed

Disruption of a -35 kb Enhancer Impairs CTCF Binding and MLH1 Expression in Colorectal Cells.

CTCF MLH1

2.21e-052164229898989
Pubmed

Differential expression of human γ-tubulin isotypes during neuronal development and oxidative stress points to a γ-tubulin-2 prosurvival function.

TUBG2 TUBG1

2.21e-052164228119396
Pubmed

Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein.

SMARCA2 SMARCA4

2.21e-05216429603422
Pubmed

[NMDA receptor and NOS in morphine tolerance in mice with bone cancer].

GRIN1 NOS1

2.21e-052164220543469
Pubmed

Extended association study of PLEKHA7 and COL11A1 with primary angle closure glaucoma in a Han Chinese population.

COL11A1 PLEKHA7

2.21e-052164224854855
Pubmed

SWI/SNF gene variants and glioma risk and outcome.

SMARCA2 SMARCA4

2.21e-052164223276717
Pubmed

Differential Expression of SWI/SNF Chromatin Remodeler Subunits Brahma and Brahma-Related Gene During Drug-Induced Liver Injury and Regeneration in Mouse Model.

SMARCA2 SMARCA4

2.21e-052164227097303
Pubmed

SMARCA4 and SMARCA2 deficiency in non-small cell lung cancer: immunohistochemical survey of 316 consecutive specimens.

SMARCA2 SMARCA4

2.21e-052164228038711
Pubmed

Proinflammatory stimuli engage Brahma related gene 1 and Brahma in endothelial injury.

SMARCA2 SMARCA4

2.21e-052164223963727
Pubmed

SW13 cells can transition between two distinct subtypes by switching expression of BRG1 and Brm genes at the post-transcriptional level.

SMARCA2 SMARCA4

2.21e-052164212493776
Pubmed

Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4.

SMARCA2 SMARCA4

2.21e-052164231375262
Pubmed

Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers.

SMARCA2 SMARCA4

2.21e-052164217075831
Pubmed

USP28 promotes tumorigenesis and cisplatin resistance by deubiquitinating MAST1 protein in cancer cells.

USP28 MAST1

2.21e-052164238498222
Pubmed

Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non-Small Cell Lung Carcinoma.

SMARCA2 SMARCA4

2.21e-052164232855269
Pubmed

Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity.

SMARCA2 SMARCA4

2.21e-052164222721696
Pubmed

Chromatin remodeling complexes interact dynamically with a glucocorticoid receptor-regulated promoter.

SMARCA2 SMARCA4

2.21e-052164218508913
Pubmed

Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling.

SMARCA2 SMARCA4

2.21e-052164211719516
Pubmed

Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: a gradient of severity in cognitive impairments.

SHANK1 SHANK2

2.21e-052164225188300
InteractionTNIK interactions

SHANK1 FKBP15 NES MATR3 CHD8 GRIN1 HUWE1 SHANK2 SIPA1L1 SYNE2 KIF5C BAIAP2 NOS1 CEP170B

2.58e-0638116214int:TNIK
CytobandXq21

RPS6KA6 ZMAT1

7.57e-0541642Xq21
GeneFamilyPDZ domain containing

SHANK1 PPP1R9A SHANK2 PDLIM3 SIPA1L1 MAST1 NOS1

3.76e-0515210971220
GeneFamilyCollagens

COL6A2 COL11A1 COL13A1 COL6A6

1.68e-04461094490
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

FKBP15 COL11A1 COL6A6 PPP1R9A NUTM2A PGM2L1 CHD3 PLEKHA6 PRDM2 SLC8A1 MDN1 SHANK2 SV2A MAST1 C2CD6 KIF5C MCF2L UNC79 ZMAT1 HYDIN GOLGA3 SH3BP5 ZNF697

4.40e-07110616423M39071
CoexpressionMULLIGHAN_MLL_SIGNATURE_2_DN

MATR3 ANKLE2 FAH UBR5 SIPA1L1 MROH7 KMT2A PRKCQ MCF2L STOM

1.11e-0527916410M16867
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SMG1 ERBB2 MACC1 MUC16 EPS8L1 ANKLE2 CAPN8 MYH14 MCF2L

2.27e-0817916496e965e424eebef50f0202cff75f458be395cfca1
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

COL11A1 ARHGEF28 PPP1R9A SHANK2 ADAMTS6 MYO3B PRKCQ KIF5C ZMAT1

3.32e-081871649db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

IQANK1 MACC1 ARHGEF28 NEUROD4 PPP1R9A SHANK2 MYH14 KIF5C

4.26e-071841648fa4915b0498f3069fd5ef497286445528f75187e
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MACC1 ARHGEF28 SHANK2 MYH14 SYNE2 PRKCQ BAIAP2 PLEKHA7

4.81e-07187164858d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MACC1 ARHGEF28 PPP1R9A SHANK2 MYH14 MYO3B KIF5C ZMAT1

5.22e-0718916487659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

MACC1 ARHGEF28 PPP1R9A MUC16 CAPN8 SHANK2 MYH14 PLEKHA7

5.43e-07190164851ca9ef4df3220487152fcf684147730637c7cc1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MACC1 ARHGEF28 PPP1R9A PLEKHA6 EPB41L4A SHANK2 SYNE2 PLEKHA7

6.36e-0719416487002937e8903e037332a215d00fbc7c7843b33f2
ToppCellhealthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

COL6A2 CHD3 JAKMIP2 SYNE2 NLRC5 ARHGAP25 PRKCQ STOM

6.87e-071961648af00c31612e4fe068e5fccae05368edba46bbd20
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NES COL6A2 RERG TBX3 DPYSL4 ARHGEF17 JAKMIP2 ZNF697

7.14e-071971648f66945f9007d59d4208849c7fd727f8519713fbc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MACC1 PPP1R9A PLEKHA6 SHANK2 MYO3B SYNE2 PLEKHA7 HYDIN

7.14e-0719716487e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

EPS8L1 SHANK2 MYH14 SYNE2 SMARCA4 BAIAP2 PLEKHA7 ZMAT1

7.14e-0719716483d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCellParenchymal-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NES COL6A2 RERG TBX3 DPYSL4 ARHGEF17 JAKMIP2 ZNF697

7.14e-07197164841dd312f46a2b983c8d864adeb6970c0ca4a8048
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ERBB2 MACC1 EPS8L1 SHANK2 MYH14 SYNE2 BAIAP2 CAVIN2

7.70e-071991648a270630626df614f8605abddb7dee7c4d74f6149
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CORT PLXND1 DYSF PPM1F MCF2L CAVIN2 STOM SH3BP5

8.00e-072001648ae6cc5462a8a254682793fb8cc348b9721c729bf
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

ERBB2 EPS8L1 SHANK2 MYH14 SYNE2 BAIAP2 CEP170B CAVIN2

8.00e-0720016482dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ERBB2 EPS8L1 SHANK2 MYH14 SYNE2 SMARCA4 BAIAP2 CAVIN2

8.00e-072001648ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGEF28 PPP1R9A MUC16 EPB41L4A CAPN8 SHANK2 MCF2L PLEKHA7

8.00e-072001648d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ERBB2 EPS8L1 SHANK2 MYH14 SYNE2 SMARCA4 BAIAP2 CAVIN2

8.00e-0720016488683445ad5b70748c4a1f12eb77d47623085147e
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NES PLXND1 DYSF ADAMTS6 PPM1F CAVIN2 STOM SH3BP5

8.00e-0720016482e47888e041ec3d265425d1df97b6665c6da889c
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NES PLXND1 DYSF ADAMTS6 PPM1F CAVIN2 STOM SH3BP5

8.00e-07200164850fa0f8a3e490d5941b34e66a10158eba6c909d4
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NES TBX3 PLXND1 DYSF TLNRD1 PPM1F CAVIN2 SH3BP5

8.00e-072001648ced14d83222dbebca85c40540e76824e683354f3
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF28 SHANK2 MYH14 SYNE2 PRKCQ BAIAP2 PLEKHA7

4.61e-061791647fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellPericytes-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

COL6A2 RERG COL13A1 CCDC168 PDLIM3 SV2A KIF5C

5.33e-061831647d04deef7cd4e1738227a6593b84874ce0168c773
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

MACC1 ARHGEF28 PLEKHA6 SHANK2 SYNE2 PLEKHA7 HYDIN

5.33e-0618316476878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MACC1 SHANK2 MYH14 SYNE2 BAIAP2 PLEKHA7 CAVIN2

5.53e-06184164742ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MACC1 COL11A1 ARHGEF28 PPP1R9A SHANK2 PRKCQ KIF5C

5.93e-061861647bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MACC1 ARHGEF28 SHANK2 MYH14 PRKCQ BAIAP2 PLEKHA7

5.93e-061861647e83718fabb057100835d3357df407f283d23fe16
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)|Adult / Lineage, Cell type, age group and donor

NES TBX3 EPB41L4A DYSF ADAMTS6 MCF2L SH3BP5

7.55e-06193164739c6c96a2a100b1b290a779d36cc6bc17245720b
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TBX3 PPP1R9A EPB41L4A DYSF SMARCA2 MCF2L SH3BP5

7.55e-061931647e1d546165dcc2392f540162206852c4717d7306f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MACC1 ARHGEF28 PPP1R9A SHANK2 MYO3B PLEKHA7 HYDIN

7.81e-06194164793c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PLXND1 EPB41L4A TLNRD1 ADAMTS6 MCF2L STOM SH3BP5

7.81e-061941647fc2e0081005c0c496e41197a2d06e4a37708221f
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MACC1 COL11A1 ARHGEF28 PPP1R9A SHANK2 MYO3B KIF5C

8.08e-06195164798dd3b7d5ef587825dac052dea4d4ff883f6d4d6
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MACC1 COL11A1 ARHGEF28 PPP1R9A SHANK2 MYO3B KIF5C

8.08e-061951647ce1ba5911e8a6ddb07434acc37147c38e94245ff
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MACC1 ARHGEF28 PPP1R9A CAPN8 SHANK2 MYO3B PLEKHA7

8.35e-061961647c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellPCW_10-12-Epithelial|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MACC1 COL11A1 ARHGEF28 PPP1R9A SHANK2 MYO3B KIF5C

8.35e-0619616479bfb31ff3e4f2c0a9405c418c86bfec5dbca23e2
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A2 RERG FBLN7 COL13A1 PDLIM3 RPS6KA6 FZD10

8.35e-061961647614a07334707eafe238d5cb7b080a3ca796a1920
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MACC1 ARHGEF28 PPP1R9A SHANK2 MYO3B PLEKHA7 HYDIN

8.35e-0619616476ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 CHD3 SYNE2 VPS13A SMARCA2 KMT2A PRKCQ

8.63e-06197164757ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Deep_Layer|World / Primary Cells by Cluster

PGM2L1 CHD3 PLXND1 CLSTN1 SMARCA4 KIF5C SH3BP5

8.63e-06197164741e823b14697827f657b13adb3afa581bd91a9cb
ToppCellCOVID-19-lung-Capillary_1|lung / Disease (COVID-19 only), tissue and cell type

TBX3 EPB41L4A DYSF ADAMTS6 SYNE2 MCF2L SH3BP5

8.63e-0619716477e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCellCOVID_vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

USP28 CHD3 JAKMIP2 SYNE2 ARHGAP25 PRKCQ STOM

8.63e-061971647d4dfb3b561d0783cdbee4e8d27009ad81df695cb
ToppCellControl_saline-Epithelial_airway|Control_saline / Treatment groups by lineage, cell group, cell type

DNAAF4 EPS8L1 JAKMIP2 FHAD1 KIF5C CFAP44 HYDIN

8.92e-061981647e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCellControl_saline-Epithelial_airway-airway_epithelial|Control_saline / Treatment groups by lineage, cell group, cell type

DNAAF4 EPS8L1 JAKMIP2 FHAD1 KIF5C CFAP44 HYDIN

8.92e-061981647e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCellCOVID-19-lung-Capillary_2|lung / Disease (COVID-19 only), tissue and cell type

NES TBX3 EPB41L4A ADAMTS6 SYNE2 MCF2L SH3BP5

9.22e-061991647793ce71b78a68033ef4419ed571e1dd86b40124f
ToppCell343B-Endothelial_cells-Endothelial-E-|343B / Donor, Lineage, Cell class and subclass (all cells)

NES TBX3 DYSF ADAMTS6 MCF2L CAVIN2 SH3BP5

9.22e-061991647bff61a784ef8bc040f5c7baabccaf7a7cddd5a31
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ERBB2 EPS8L1 SHANK2 MYH14 SYNE2 BAIAP2 CAVIN2

9.22e-061991647d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLXND1 DYSF PPM1F SYNE2 CAVIN2 STOM SH3BP5

9.22e-06199164714e09eaa2335d4503de50250eb4258dd5b85b304
ToppCell343B-Endothelial_cells-Endothelial-E|343B / Donor, Lineage, Cell class and subclass (all cells)

NES TBX3 DYSF ADAMTS6 MCF2L CAVIN2 SH3BP5

9.22e-0619916473cb1d9d9de64ed0a56c4f8d5e2fa02a13a73d8ac
ToppCellKidney-Endothelial|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.

NES PLXND1 DYSF PPM1F CAVIN2 STOM SH3BP5

9.22e-061991647b543f0686522df43737e9ffa5c9733e42b8a9f4d
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PPP1R9A EPB41L4A UBR5 SYNE2 KMT2A MCF2L SH3BP5

9.53e-062001647dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellmild-CD8+_Tem|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 COL6A2 USP28 JAKMIP2 SYNE2 KMT2A N4BP1

9.53e-062001647d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NES PLXND1 DYSF ADAMTS6 CAVIN2 STOM SH3BP5

9.53e-062001647dba96cda5f3b780a3d4171b61bc8aaddc1f5d466
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NES PLXND1 DYSF ADAMTS6 CAVIN2 STOM SH3BP5

9.53e-0620016477a69ad5b6c84f1aebacea5cacb9bc5c63dfd1dac
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGEF28 PPP1R9A MUC16 CAPN8 SHANK2 MCF2L PLEKHA7

9.53e-0620016470eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP7A COL6A6 FARP2 MED15 C2CD6 GOLGA3

2.39e-051551646441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATP7A MYOM3 C4orf17 SYNE2 PRKCQ MCF2L

2.96e-0516116465fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCellmild_COVID-19_(asymptomatic)-B_intermediate|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

MACC1 MATR3 EPB41L4A PRDM2 ARHGAP25 DNAH8

3.51e-0516616468de8f388f24436b84e19ef460476fdbda4d16abf
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MACC1 MUC16 CHD3 EPS8L1 CAPN8 MYH14

3.88e-05169164640b557549fe08c5dc9dba359af35993d68d1640a
ToppCellT_cells-GNLY+GZMB+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

USP28 CAPN8 FHAD1 MYH14 MYO3B ARHGAP25

4.14e-05171164604c811817cfec45af5f2891793106cc7ddb0300e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF4 C2orf81 RPS6KA6 CROCC CFAP44 HYDIN

4.42e-051731646a7cc63bb3ab41feb9e4072700d44dbbbc62c47c6
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 CORT AGPAT3 DNAH8 GPANK1 TBL2

4.42e-0517316468bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 CORT AGPAT3 DNAH8 GPANK1 TBL2

4.42e-0517316463e3c61468e703330788a10d850ef41a85680f86d
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF4 C2orf81 RPS6KA6 CROCC CFAP44 HYDIN

4.42e-051731646e3e3a67a5a93ef4475224a256d45ae24526383cc
ToppCell3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DYSF PDLIM3 MYO3B CAVIN2 STOM SH3BP5

4.42e-051731646b57d14e2c2368304cb903562d06ce8228f53857c
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL11A1 COL6A6 MUC16 GDF2 SYNE2 KIF5C

4.56e-051741646a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCell(1)_T_regulatory|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

FBLN7 PGM2L1 RAB33A THADA SYNE2 DNAH8

5.02e-0517716465cda56b10df1ee8971ce8470d52062e01b703a4e
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-1|TCGA-Liver / Sample_Type by Project: Shred V9

COL11A1 COL13A1 DNAAF4 EPS8L1 EPB41L4A C2orf81

5.18e-05178164651c59dabf2d7aef1b1964f6f766d5ec07ef90f5a
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

RERG ARHGEF28 PLEKHA6 SHANK2 SYNE2 HYDIN

5.18e-051781646544379f5a6145429762258d426b876bb36c112f5
ToppCelldroplet-Fat-Gat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRTG CCDC174 DYSF TUBGCP6 MCF2L SH3BP5

5.34e-05179164608cf9986804a6417a9afb19b50c69a3554f71ec6
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLXND1 DYSF TLNRD1 PPM1F MCF2L CAVIN2

5.51e-05180164697e0dcb7cfbba60a782824c5e23995058609fcd4
ToppCellFetal_29-31_weeks-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TBX3 PLXND1 EPB41L4A DYSF TLNRD1 SH3BP5

5.51e-051801646d8ef44710a77ad0fc03243428e5e1dc4d41200cb
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MACC1 ARHGEF28 SHANK2 MYH14 PRKCQ BAIAP2

5.68e-0518116460513b9e6673ff7bf8e72ba123ca3794b65d10170
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(other)|COVID-19 / group, cell type (main and fine annotations)

TBX3 EPB41L4A ADAMTS6 SYNE2 MCF2L CAVIN2

5.68e-05181164626eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCellPericytes-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

COL6A2 RERG TBX3 DPYSL4 PDLIM3 FZD10

5.68e-051811646ff445a8e56522e57e27405184d123cf905caf8cc
ToppCell3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NES PLXND1 TUBG1 TLNRD1 PPM1F CAVIN2

5.68e-0518116464a225d9a6d113396c6b1d0a839bb4ca9c339a260
ToppCellNS-moderate-d_16-33-Lymphoid-NK|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NES COL6A2 TBX3 PRTG PDLIM3 NOS1

5.86e-051821646fb503f8ecd013f1f2161a5841572b57cfcddb6fa
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

ARHGEF28 MUC16 PLEKHA6 CAPN8 MYH14 MXD1

6.04e-05183164615d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NES PLXND1 MCF2L CAVIN2 STOM SH3BP5

6.04e-051831646a644258ba90acc62d571623e429d72ffc4b69203
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ERBB2 MACC1 SHANK2 MYH14 BAIAP2 PLEKHA7

6.04e-051831646ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PLXND1 EPB41L4A ADAMTS6 MCF2L CAVIN2 SH3BP5

6.04e-051831646c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MACC1 ARHGEF28 SHANK2 MYH14 PRKCQ BAIAP2

6.04e-051831646e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP8B3 NES PLXND1 DYSF PPM1F CAVIN2

6.22e-051841646fa38d6a8709f520a027ad7e3ff783c84187ec467
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL11A1 SPTA1 CAPN8 SLC8A1 UNC79 HYDIN

6.22e-0518416462cbed6462fea2622871bb7e49b0df3d984239281
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IPO7 EPB41L4A DYSF PTPN11 N4BP1 SH3BP5

6.22e-051841646c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A2 RERG COL6A6 ARHGEF17 FHAD1 SLC8A1

6.22e-051841646689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL11A1 SPTA1 CAPN8 SLC8A1 UNC79 HYDIN

6.22e-051841646ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL11A1 SPTA1 CAPN8 SLC8A1 UNC79 HYDIN

6.22e-0518416462b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MACC1 ARHGEF28 SHANK2 MYH14 PRKCQ BAIAP2

6.22e-051841646ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

ARHGEF28 MUC16 EPS8L1 PLEKHA6 CAPN8 MYH14

6.22e-051841646d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP8B3 TBX3 NEUROD4 EPS8L1 MAST1 KIF5C

6.41e-051851646ef996f4cdbc3971c6c0460d13df64b075ab22154
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MACC1 ARHGEF28 SHANK2 MYH14 PRKCQ PLEKHA7

6.41e-0518516460d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RREB1 NEU2 NEK8 CFAP44 PLEKHA7 HYDIN

6.41e-05185164605bc89a566b0db90ae06506e067190a4739a0974
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP8B3 TBX3 NEUROD4 EPS8L1 MAST1 KIF5C

6.41e-051851646d51342a3979bd728a80e04126059a3fd8a0dbe3b
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

ERBB2 PPP1R9A CAPN8 SHANK2 MYH14 PLEKHA7

6.41e-051851646cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellmoderate-Lymphoid-NK|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NES COL6A2 TBX3 PRTG COL13A1 PDLIM3

6.41e-0518516464979a787acbc9b4ca8defe91cc79b674e51af1bf
ToppCellLPS_only-Epithelial_alveolar|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MACC1 ARHGEF28 SHANK2 MYH14 BAIAP2 PLEKHA7

6.61e-051861646e0a2ea4b46af742bc7c9b2072bb85e27d5c92712
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MACC1 ARHGEF28 SHANK2 MYH14 PRKCQ PLEKHA7

6.61e-0518616464e94158db52df41d71e67b02b9895a358eebee0f
ToppCellSubstantia_nigra-Neuronal|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SHANK1 PGM2L1 GRIN1 CLSTN1 MAST1 UNC79

6.61e-0518616463f889083fcffe516388e9b03a5e23af2010ced33
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MACC1 COL11A1 ARHGEF28 PPP1R9A SHANK2 KIF5C

6.80e-051871646c2940aec30b3c2c113f6a65126dc6f1969cf301e
ToppCellLPS-antiTNF-Epithelial_alveolar|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MACC1 ARHGEF28 SHANK2 MYH14 PRKCQ BAIAP2

6.80e-051871646201ff693e4756ee3e44762885b3a303a77eb535b
DiseaseTodd Paralysis

ATP7A TRPM7 CHRND

1.28e-0591603C0234544
DiseaseParalysed

ATP7A TRPM7 CHRND

1.28e-0591603C0522224
Diseasecomplex cortical dysplasia with other brain malformations 4 (implicated_via_orthology)

TUBG2 TUBG1

2.92e-0521602DOID:0090138 (implicated_via_orthology)
Diseasereticulocyte count

ARHGEF28 SPTA1 PEX12 RREB1 PLEK2 THADA PTPN11 DCAF10 NEK8 TESK2 SYNE2 VPS13A MTMR3 MAST1 PCBD1 PLEKHA7 MXD1

5.66e-05104516017EFO_0007986
Diseaselevel of Sphingomyelin (d32:1) in blood serum

ERMP1 SYNE2 SMARCA4

1.01e-04171603OBA_2045173
DiseaseInfiltrating duct carcinoma of female breast

SMG1 TRPM7 TESK2

1.94e-04211603C3165106
Diseaseactivities of daily living score measurement

FARP2 FZD10 NOS1

1.94e-04211603EFO_0008451
Diseasefactor VII measurement

PRTG PRKCQ MCF2L TBL2

2.29e-04551604EFO_0004619
Diseasefactor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement

FARP2 MCF2L PLRG1 TBL2

2.46e-04561604EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 12

SMARCA2 SMARCA4

2.89e-0451602C3281201
Diseasetransient cerebral ischemia (implicated_via_orthology)

PPP1R9A PLXND1 KMT2A NOS1

4.11e-04641604DOID:224 (implicated_via_orthology)
DiseaseNeoplasm of uncertain or unknown behavior of ovary

ERBB2 MLH1 SMARCA4

5.15e-04291603C0496920
DiseaseProstatic Neoplasms

TBX3 ERBB2 USP28 CHD3 WAC PLEK2 CTCF MYH14 MLH1 KMT2A POLK

5.66e-0461616011C0033578
DiseaseOvarian Carcinoma

ERBB2 MLH1 SMARCA4

5.70e-04301603C0029925
Diseasepalmitoyl dihydrosphingomyelin (d18:0/16:0) measurement

SYNE2 SMARCA4

6.03e-0471602EFO_0800400
DiseaseAngle Closure Glaucoma

COL11A1 PLEKHA7

6.03e-0471602C0017605
Diseasealcohol use disorder (implicated_via_orthology)

ERBB2 EPS8L1 CHRND SMARCA2 SMARCA4 UNC79

7.04e-041951606DOID:1574 (implicated_via_orthology)
Diseasefemale breast cancer (is_implicated_in)

CTCF MAST1

8.01e-0481602DOID:0050671 (is_implicated_in)
Diseaseopportunistic bacterial infectious disease (implicated_via_orthology)

SMARCA2 SMARCA4

1.03e-0391602DOID:0050340 (implicated_via_orthology)
Diseasespinal muscular atrophy (implicated_via_orthology)

ATP7A KIF5C

1.03e-0391602DOID:12377 (implicated_via_orthology)
Diseasethoracic aortic calcification measurement

COL6A6 VPS13A

1.03e-0391602EFO_0010273
Diseaseprimary angle closure glaucoma

COL11A1 PLEKHA7

1.56e-03111602EFO_1001506
DiseaseMacrocephaly

CHD8 CHD3

1.56e-03111602C0221355
Diseaseage at menarche

IQANK1 COL11A1 ADCK1 ERMP1 INO80 PRDM2 PPM1F SMARCA2 PLEKHA7 UNC79

1.56e-0359416010EFO_0004703
Diseasereticulocyte measurement

ARHGEF28 SPTA1 PEX12 RREB1 PLEK2 NEK8 TESK2 SYNE2 VPS13A MTMR3 MAST1 ARHGAP25 PLEKHA7 MXD1

1.84e-03105316014EFO_0010700
DiseaseAdenocarcinoma of large intestine

ERBB2 UBR5 MLH1 PRKCQ

1.88e-03961604C1319315
Diseasefibrinogen measurement, tissue plasminogen activator measurement

PLXND1 FARP2 PLRG1

1.88e-03451603EFO_0004623, EFO_0004791
DiseaseMalignant neoplasm of prostate

TBX3 ERBB2 USP28 CHD3 WAC PLEK2 MYH14 MLH1 KMT2A POLK

2.03e-0361616010C0376358
DiseaseCoffin-Siris syndrome

SMARCA2 SMARCA4

2.19e-03131602C0265338
Diseaseattention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia

CWC22 SMARCA2 KMT2A KIF5C

2.26e-031011604EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090
DiseaseMalformations of Cortical Development

TUBG1 KIF5C

2.55e-03141602C1955869
Diseasetriacylglycerol 46:2 measurement

JAKMIP2 MYO3B

2.55e-03141602EFO_0010402
DiseaseCortical Dysplasia

TUBG1 KIF5C

2.55e-03141602C0431380
Diseaseasthma

ERBB2 ZNF652 MUC16 ERMP1 DYSF SLC8A1 SMARCA2 MROH7 PRKCQ UNC79 GPANK1

2.73e-0375116011MONDO_0004979
Diseasetriacylglycerol 46:0 measurement

CWC22 JAKMIP2

2.93e-03151602EFO_0010400
Diseaseosteoarthritis (implicated_via_orthology)

COL11A1 ATP7A

2.93e-03151602DOID:8398 (implicated_via_orthology)
DiseaseTremor, Rubral

ATP7A GABRA4

3.34e-03161602C0750940
DiseaseAtaxia, Appendicular

ATP7A GABRA4

3.34e-03161602C0750937
DiseaseMyasthenic Syndromes, Congenital, Slow Channel

COL13A1 CHRND

3.34e-03161602C0751885
DiseaseAtaxia, Motor

ATP7A GABRA4

3.34e-03161602C0278161
DiseaseAtaxia, Sensory

ATP7A GABRA4

3.34e-03161602C0240991
DiseaseAbnormal coordination

ATP7A GABRA4

3.34e-03161602C0520966
DiseaseAtaxia, Truncal

ATP7A GABRA4

3.34e-03161602C0427190
Diseaseprostate specific antigen measurement

SHANK1 TBX3 CHD3 DYSF THADA

3.69e-031881605EFO_0004624
DiseaseBenign neoplasm of stomach

ERBB2 UBR5

3.77e-03171602C0153943
DiseaseCongenital Myasthenic Syndromes, Postsynaptic

COL13A1 CHRND

3.77e-03171602C0751883
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ERBB2 UBR5

3.77e-03171602C0496905
DiseaseCarcinoma in situ of stomach

ERBB2 UBR5

3.77e-03171602C0154060
Diseasesphingomyelin 14:0 measurement

THADA SYNE2

3.77e-03171602EFO_0010390
DiseaseCocaine-Related Disorders

GRIN1 CRHR1 SMARCA4 DNAH8

3.84e-031171604C0236736
DiseaseCongenital Myasthenic Syndromes, Presynaptic

COL13A1 CHRND

4.70e-03191602C0751884
DiseaseCentral precocious puberty

PLEKHA8P1 PRKCQ

4.70e-03191602EFO_0009029
Diseaselaryngeal squamous cell carcinoma (is_marker_for)

ERBB2 MLH1

4.70e-03191602DOID:2876 (is_marker_for)
DiseaseHereditary Non-Polyposis Colon Cancer Type 2

MLH1 SMARCA4

4.70e-03191602C1333991
DiseaseCocaine Abuse

GRIN1 CRHR1 SMARCA4 DNAH8

5.13e-031271604C0009171
DiseaseOsteoarthritis of hip

COL11A1 CRHR1

5.21e-03201602C0029410
DiseaseSarcomatoid Renal Cell Carcinoma

SHANK1 ERBB2 CASP2 SYNE2

5.28e-031281604C1266043
DiseaseChromophobe Renal Cell Carcinoma

SHANK1 ERBB2 CASP2 SYNE2

5.28e-031281604C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

SHANK1 ERBB2 CASP2 SYNE2

5.28e-031281604C1266044
DiseasePapillary Renal Cell Carcinoma

SHANK1 ERBB2 CASP2 SYNE2

5.28e-031281604C1306837
DiseaseRenal Cell Carcinoma

SHANK1 ERBB2 CASP2 SYNE2

5.28e-031281604C0007134
Diseasesusceptibility to cold sores measurement

MUC16 DYSF DCAF10

5.34e-03651603EFO_0008402
Diseasebone density

TTF2 MACC1 EPS8L1 PLXND1 RREB1 SLC8A1 ARHGAP25

5.40e-033881607EFO_0003923

Protein segments in the cluster

PeptideGeneStartEntry
GMEHLREVRAVTSAN

ERBB2

346

P04626
RSDLMFEKQSERHGL

CHRND

396

Q07001
VARGKAMVRSHRVTT

BTNL10

106

A8MVZ5
EGRNAEKVSQMLRHF

ADCK1

236

Q86TW2
GHRRTESEMSARIAK

ANKLE2

786

Q86XL3
SHGRFKRRMTERDVE

CHD8

1466

Q9HCK8
DSEHMQEAAGIRKSS

CORT

31

O00230
GKTFTRRNTMARHAD

CTCF

561

P49711
HATQRVMEAEQTKTR

SH3BP5

161

O60239
RAREEHTSAVNKMFS

FBXO4

246

Q9UKT5
RATRDLVDDMGRHKS

ATP8B3

196

O60423
LVDDMGRHKSDRAIN

ATP8B3

201

O60423
DAHEMRTALRKAGFT

CAPN8

626

A6NHC0
HRRTMRDQDTGKENE

CLSTN1

886

O94985
MAEARAVSRKAANTA

CEP170B

1211

Q9Y4F5
DVDSQIRAEMHRKTA

CFAP44

981

Q96MT7
MTRTFHDLEGNAVKR

ERMP1

691

Q7Z2K6
GSVHIEVREVAMSKN

ADAMTS6

741

Q9UKP5
DFMTEHERKGRTAVL

ATP7A

1201

Q04656
LNDRSRSHSGKVEMK

CPXCR1

106

Q8N123
EKPMEGESRNRNVHS

ITIH4

606

Q14624
RRSPTHEKNTMGAQE

OPALIN

86

Q96PE5
MNSGKAHERARAVNT

MROH7

571

Q68CQ1
DTAGQERFRKSMVEH

RAB33A

91

Q14088
MSLKSERRGIHVDQS

RABGEF1

1

Q9UJ41
HSSGTKETRLELREM

GDF2

261

Q9UK05
AMDRAHRLGQTKQVT

INO80

1206

Q9ULG1
NGHVFRKQALMSEER

ARHGEF28

1071

Q8N1W1
DRRNSMKLQHAASVT

ARHGEF17

1761

Q96PE2
GQETRFAEGIRHMKS

FBLN7

46

Q53RD9
EDMRHPGSRKFNTTE

MUC16

13026

Q8WXI7
VHRMNSAEGRRKAFA

OR2T2

226

Q6IF00
HEQEMSRTVKVRDGE

JAKMIP2

96

Q96AA8
GSAINSRETMFHKER

PRKCQ

211

Q04759
NERSMGDHNERVHKR

MDN1

5106

Q9NU22
SERTKPRMHEFQSEV

KLHL6

306

Q8WZ60
SSRSTHNEMEKNRRA

MXD1

56

Q05195
TSRVVHIMDFQRGKN

MATR3

396

P43243
RHGQGRSLEAEDKMT

GPANK1

91

O95872
EMNRKHSGSRSDEDR

CWC22

856

Q9HCG8
SRRMVSSGLVHINDK

C2CD6

591

Q53TS8
TSRMHQRFLDGKDGD

CCDC97

286

Q96F63
SKKTRRHTEGMQADA

COL11A1

1551

P12107
EDAGARARHKMTIAA

MYH14

1821

Q7Z406
RSLKRTHDMFVADNG

PLRG1

16

O43660
MAGKAHRLSAEERDQ

PCBD1

1

P61457
QDHVTVEMSVRVNGR

PLXND1

676

Q9Y4D7
ATLADQRRAAHESKM

IPO7

996

O95373
AVAGVMITASHNRKE

PGM2L1

166

Q6PCE3
SSEKHMSRASQREGV

DCAF10

376

Q5QP82
FLTAMRQEVTRAHKG

DNAH8

4356

Q96JB1
EARQHNTEIRMAVSK

FKBP15

511

Q5T1M5
VHAGSAKAAVDAMTR

DECR2

176

Q9NUI1
SQIEDAMRKAGVAHS

MED15

21

Q96RN5
HTDVGSVRMRRAEKS

NEK8

266

Q86SG6
RVAHMETSLGQARER

NES

196

P48681
VLRAVEQAMGHSQDR

LRRC45

216

Q96CN5
EEMAKSSRASAARVG

LRRC45

271

Q96CN5
MRKRTNALVHSESDV

GABRA4

386

P48169
RMERVARHSSVSKEE

TUBGCP6

646

Q96RT7
RNDVSHVVKGAMVAT

RPS6KA6

696

Q9UK32
GVMRVRNVKESAAHD

PTPN11

381

Q06124
HRMNSAEGRRKAFAT

OR2T35

226

Q8NGX2
ETQHRSMKEKGRIAA

GOLGA3

626

Q08378
GRALAMAESTEKHAR

HUWE1

2161

Q7Z6Z7
SQHILLRGDKTSRDM

NLRC5

1071

Q86WI3
RARHQQMSGDVAVEK

MAST1

886

Q9Y2H9
RFGSKAHMERLEEVN

NOS1

376

P29475
IAATVAHRRKSMEAS

PRTG

206

Q2VWP7
QEVVAQARLDGHRSM

NEU2

71

Q9Y3R4
DTVDNEHMGRRSSKC

PPP1R11

46

O60927
FHIRRVMKTGGENTD

FZD10

421

Q9ULW2
ADDHIARRTAQKIMA

DPYSL4

546

O14531
QRLRDKTDGAMQAHE

CROCC

571

Q5TZA2
KDLTEAHSRMSDLRG

FHAD1

1016

B1AJZ9
AHSRMSDLRGELNEK

FHAD1

1021

B1AJZ9
EFDVVFHSQKVGRMR

HYDIN

3571

Q4G0P3
TDKARMARHVLDNSG

DCAKD

166

Q8WVC6
AFSRAHRIGQANKVM

CHD3

1166

Q12873
HRRNTSMEPAAETGK

C4orf17

231

Q53FE4
MTEQIRQDRSKGTVH

COL6A2

141

P12110
SAVMGHRSDVEAIAK

CYBC1

141

Q9BQA9
QARSGGDERKARMHE

CC2D1B

401

Q5T0F9
EDTAGSRTGRKQHMK

DNAAF8

466

Q8IYS4
NSMRRVKEDTAAHIA

CEP162

1206

Q5TB80
QDKHSIRARVARAMS

CRHR1

411

P34998
RKHFRSGRIAQSMSE

MACC1

6

Q6ZN28
ASMEEVFHRRQASLK

MCF2L

541

O15068
DARDHSGATARMLAK

ANKS3

196

Q6ZW76
NANARMKAHVRRGTA

DNAAF4

361

Q8WXU2
EHMGSSSRDRRQKGK

KMT2A

2416

Q03164
MAHEGSRQVRDRGVT

C2orf81

1

A6NN90
KRKEMEASGAHRDSQ

CCDC174

121

Q6PII3
RHVDKGTAEGAVDAM

EMC1

76

Q8N766
RQHATNVGIMFRDKE

FAH

131

P16930
VGRHSPASEEMKRQN

CCDC168

2636

Q8NDH2
MVAERTHKAAATGAR

COL13A1

1

Q5TAT6
AAQKAVRAMAVLTDH

DDAH2

191

O95865
GVHTVEDASRKLAVM

EPS8L1

51

Q8TE68
IRFHMASDREGTKIQ

FARP2

231

O94887
VSAHTRAVKERMDRQ

CAVIN2

121

O95810
TVHQRRNGSKDSLME

EPB41L4A

641

Q9HCS5
DHETMGRNRFLGEAK

DYSF

71

O75923
TFQHKELMAADRGRR

CASP2

11

P42575
DHMFTEARGSRLNKG

COL6A6

896

A6NMZ7
HVTSRFKNEVERMGF

MTMR3

156

Q13615
SNHRRRTADAEIKMQ

PRDM2

1511

Q13029
AARERGSHDNITVMV

PPM1F

396

P49593
RAHTGMARSKDSVVL

NUTM2A

686

Q8IVF1
HRKEAFSIGMQRDLS

PLEKHA8P1

361

O95397
MRVETAADGKTTRHN

GTF2E1

76

P29083
FATMRRKEGTSVLEH

UTP15

491

Q8TED0
HSVAKETARRRAMLD

SNAPIN

111

O95295
KDEHSKTNRMTGREF

THADA

1271

Q6YHU6
SMRVFDERHKKENGT

TBX3

321

O15119
AGMFDQKSSSHERRA

SMARCA2

1201

P51531
ENRTDTASRLKQMVH

SYNE2

6206

Q8WXH0
EAVRAKNMARRAHSA

KIF5C

906

O60282
VFRDNSRELHTMTKA

NKPD1

471

Q17RQ9
FSRETDGAQKRRMLH

ING1

201

Q9UK53
VQHGSRALATKDMRK

SMG1

121

Q96Q15
KMSSEERRAHRDGTV

PLEKHA7

506

Q6IQ23
SVQHGSRALATKDMR

nan

116

Q6P435
AGMFDQKSSSHERRA

SMARCA4

1231

P51532
SVGFMDTRKRHQSDG

SIPA1L1

1496

O43166
GTESMTHADAQDRIK

PDLIM3

56

Q53GG5
RGDAVAKASKETHVM

PSME2

171

Q9UL46
KQASRLREEAHNMGT

WAC

581

Q9BTA9
QRHKEAEAERCGSMT

IQANK1

301

A8MXQ7
HQMVRTDSREQKLDA

MLH1

381

P40692
RIVMGDTHKSQRLAS

PEX12

91

O00623
MAEKRHTRDSEAQRL

STOM

1

P27105
NMRAKGHPERVFSVT

SV2A

381

Q7L0J3
TAGQEDTIQREGHMR

RERG

61

Q96A58
GMTALHKAARARNQV

SHANK2

231

Q9UPX8
DFRARDGMTALHKAA

SHANK1

241

Q9Y566
RMRVKAIFSHAAGDN

BAIAP2

376

Q9UQB8
VEEQIDRMRRHQSGS

PLEKHA6

821

Q9Y2H5
GDHTNRVKRIATAPM

WDTC1

131

Q8N5D0
RIVDKMHDSNTGIRS

PLEK2

131

Q9NYT0
VKNSAESEGMRRAHI

XPNPEP1

321

Q9NQW7
ESEGMRRAHIKDAVA

XPNPEP1

326

Q9NQW7
RCRKSHGEVTQKDDM

VPS13A

2461

Q96RL7
EGTRFTETKHRVSME

AGPAT3

176

Q9NRZ7
KNVMVSTGRDRQTNH

TUBG1

301

P23258
HMAVTRSRKEGLASA

RREB1

1611

Q92766
AKAGEGHRRTMSQDL

ARHGAP25

476

P42331
HLTRDGERKSMSVER

POLK

406

Q9UBT6
GAKMSDHRERLRNSA

TLNRD1

316

Q9H1K6
NMQGRVDHTVASDIR

USF3

1716

Q68DE3
LEKTREERFTMGHSA

SPTA1

111

P02549
RDLNRMHEATSAETK

USP28

121

Q96RU2
EREMGSNPHDTNKRE

ZNF697

36

Q5TEC3
KNVMVSTGRDRQTNH

TUBG2

301

Q9NRH3
EVFKVRHRASGQVMA

TESK2

71

Q96S53
HGEAGVRRIKMATAD

TKFC

221

Q3LXA3
AVHVAGMAQEDSRRG

ZNF652

16

Q9Y2D9
EMQGHLKRASNESTR

TBL2

411

Q9Y4P3
VGHRDSMDLQRFKET

TRPM7

1441

Q96QT4
ENRKRHGSSRSVVDM

UBR5

2476

O95071
KQRMDLVEAFNHSRG

TTF2

1046

Q9UNY4
KIGDSSVETHRNREM

ZMAT1

416

Q5H9K5
MDISRGNHRDNKAVI

UNC79

2371

Q9P2D8
EMIQRKGSTFRPHDS

KIAA1522

131

Q9P206
RHAADQARKAVSMHE

SLC8A1

381

P32418
IADETGRVMHDITSK

MYO3B

561

Q8WXR4
RGSAEAVVMARSHIQ

N4BP1

121

O75113
EQKEERQHSLRMGSS

MYOM3

31

Q5VTT5
ETRKMFERSVHESGQ

PPP1R9A

141

Q9ULJ8
KANARERTRMHGLND

NEUROD4

91

Q9HD90
AVLSTRKHEQMFREA

GRIN1

31

Q05586