Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
PathwayWP_EDA_SIGNALING_IN_HAIR_FOLLICLE_DEVELOPMENT

BMP1 PTCH1

2.14e-0413242M39558
PathwayWP_OSTEOCLAST_SIGNALING

TNFRSF11B IFNAR1

2.50e-0414242MM15987
PathwayWP_OSTEOCLAST_SIGNALING

TNFRSF11B IFNAR1

3.29e-0416242M39694
PathwayREACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS

PTCH1 ADGRE3 WNT11

5.25e-0494243M797
Pubmed

IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection.

ICOS IFNAR1

1.16e-06238227812214
Pubmed

No association between selected candidate gene polymorphisms and severe chronic periodontitis.

ICOS TNFRSF11B

4.16e-05938216512757
Pubmed

Tissue specific requirements for WNT11 in developing outflow tract and dorsal mesenchymal protrusion.

PTCH1 WNT11

5.20e-051038228669819
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

MON2 MED24 COP1 BMP1 HELZ LLGL2 ZBED4 TMEM151B

7.74e-05132738832694731
Pubmed

Fgf8 is required for anterior heart field development.

PTCH1 WNT11

1.05e-041438216720880
Pubmed

Functional screening of FxxLF-like peptide motifs identifies SMARCD1/BAF60a as an androgen receptor cofactor that modulates TMPRSS2 expression.

MED24 MDN1

1.21e-041538219762545
Pubmed

Kif3a controls murine nephron number via GLI3 repressor, cell survival, and gene expression in a lineage-specific manner.

PTCH1 WNT11

1.38e-041638223762375
Pubmed

The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.

PTCH1 TNFRSF11B IFNAR1

1.76e-049938319730683
Pubmed

Villification in the mouse: Bmp signals control intestinal villus patterning.

BMP1 PTCH1

1.76e-041838226721501
Pubmed

GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells.

PTCH1 WNT11

1.76e-041838219809516
Pubmed

Dermal β-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation.

PTCH1 WNT11

2.41e-042138222434869
Pubmed

Conditional Deletion of Indian Hedgehog in Limb Mesenchyme Results in Complete Loss of Growth Plate Formation but Allows Mature Osteoblast Differentiation.

PTCH1 TNFRSF11B

2.65e-042238226094741
Pubmed

KLF13 is a genetic modifier of the Holt-Oram syndrome gene TBX5.

BMP1 NOS3

2.90e-042338228164238
Pubmed

Primary cilia in murine palatal rugae development.

PTCH1 WNT11

2.90e-042338231226309
Pubmed

Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta3-catenin signaling.

PTCH1 WNT11

3.16e-042438219165927
Pubmed

Atmin mediates kidney morphogenesis by modulating Wnt signaling.

PTCH1 WNT11

3.16e-042438224852369
Pubmed

A cluster of three long-range enhancers directs regional Shh expression in the epithelial linings.

PTCH1 WNT11

3.43e-042538219369396
Pubmed

A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney.

PTCH1 WNT11

3.72e-042638219060336
Pubmed

Analysis of multiple candidate genes in association with phenotypes of multiple sclerosis.

HELZ IFNAR1

3.72e-042638220378664
Pubmed

Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme.

PTCH1 WNT11

4.32e-042838218367557
Pubmed

Role of inflammation gene polymorphisms on pain severity in lung cancer patients.

NOS3 IFNAR1

6.01e-043338219773451
Pubmed

Hox5 Genes Regulate the Wnt2/2b-Bmp4-Signaling Axis during Lung Development.

PTCH1 WNT11

7.15e-043638226235626
Pubmed

Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.

NOS3 IFNAR1

7.15e-043638220811626
Pubmed

Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium.

LLGL2 PTCH1

7.56e-043738223266329
Pubmed

High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.

PTCH1 TNFRSF11B WNT11 IFNAR1

7.95e-0438338419453261
Pubmed

Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development.

HIP1R IFNAR1

7.97e-043838229799838
Pubmed

Expansion of the renal capsular stroma, ureteric bud branching defects and cryptorchidism in mice with Wilms tumor 1 gene deletion in the stromal compartment of the developing kidney.

PTCH1 WNT11

7.97e-043838232715478
Pubmed

Systematic identification of NF90 target RNAs by iCLIP analysis.

MED24 PTCH1

9.28e-044138235013429
Pubmed

Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.

HIP1R LLGL2 ACADSB

1.06e-0318338331932471
GeneFamilyProteases, serine

KLK8 TMPRSS13

3.40e-0363252738
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-5|TCGA-Stomach / Sample_Type by Project: Shred V9

SLC5A12 TMPRSS13 DNAH14 TMEM151B

3.07e-06121374392700c5032b83d4d4e191fea9bcd170e4567b9d
ToppCellBL-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TMPRSS13 NXPH2 TNFRSF11B WNT11

1.18e-05170374b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGB ICOS PTCH1 TMPRSS13

1.21e-051713746f49537f8d3cf18e65aa999fec32ed347ce2da3e
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGB ICOS PTCH1 TMPRSS13

1.21e-05171374ab97ae2b127a585f170f028f1c475cdd1b0cdea5
ToppCelldroplet-Fat-Mat-18m-Lymphocytic-lymphocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLK8 PIGB MDN1 ICOS

1.23e-05172374226de1a5d4a360d3ae01b0235fea19521ec623a0
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIGB POPDC2 ICOS TMPRSS13

1.38e-0517737444c38e572a9e9678c2dbb3e8b4748e7e28d404b7
ToppCellNS-critical-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TMPRSS13 NXPH2 TNFRSF11B WNT11

1.57e-05183374ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCellcritical-Epithelial-Ionocyte|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TMPRSS13 NXPH2 TNFRSF11B WNT11

1.61e-0518437458d36577eff814d46d72f031f3533d71549e3d6e
ToppCellmoderate-Epithelial-Ionocyte|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TMPRSS13 NXPH2 TNFRSF11B WNT11

1.71e-051873743e3fe2d5712a0ac477cddefe56705d4b8d8f7eac
ToppCellcritical-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TMPRSS13 NXPH2 TNFRSF11B WNT11

1.82e-0519037405a2c3549b68f49081723bf35db14974274419d5
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLK8 MDN1 ICOS

2.55e-0414937365778f19599b4955c0a16f0121237656449431fb
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DDHD2 MDN1 TNFRSF11B

2.81e-0415437316fdafb5c64d2db321554f87129a962d113f1668
ToppCellPND07-28-samps-Lymphocyte-T_cells|PND07-28-samps / Age Group, Lineage, Cell class and subclass

KLK8 ICOS TMEM151B

2.97e-04157373f3b4cde52423246ae6fc4924cd1ee502cf6c009c
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

IGSF1 PTCH1 WNT11

2.97e-04157373b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MED24 POPDC2 NEB

3.14e-041603735cc1b75e3c20d83112b3aa2f3c749a6c73910a2d
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma|TCGA-Brain / Sample_Type by Project: Shred V9

HIP1R NCR3LG1 TMEM151B

3.20e-041613735f6b2d7f80a8ee16651e304481d2da3fae313824
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATG4A RNF10 POPDC2

3.25e-0416237308ee7ae56e4927874515c47adc86dd845bf29a26
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

TCAF2 ICOS NEB

3.56e-04167373c0c944eae0514dc8e00d0c2892a0792e157695ec
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POPDC2 ICOS NEB

3.56e-04167373eed22d1a17aab84dacb1a488528bae9389644cb9
ToppCelldroplet-Lung-nan-3m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLK8 ICOS NEB

3.62e-041683731df3c8c7a6dceb901805eaba7f86f9943f4f1a9d
ToppCelldroplet-Lung-nan-3m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLK8 ICOS NEB

3.62e-041683731586451d437b70b2dffe41d782b694702dcaf50b
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D23 NEB TMPRSS13

3.68e-04169373befb9b1618ea30fbf8983bcc493853da53b809c3
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D23 NEB TMPRSS13

3.68e-04169373d18b823836ca6fba79a2d2f10cb9966fa2623af2
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLK8 ICOS TMPRSS13

3.75e-04170373d74fbd995a8a37fc237f7147d398357b811d6452
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ICOS NEB TMPRSS13

3.88e-04172373ce444463f69bbb05c933615a0f1f43ddde3eee1c
ToppCelldroplet-Lung-LUNG-1m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ICOS NEB TMPRSS13

3.88e-041723732c993a93ac91dcf6061eec001f51f8cccb6ee264
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLK8 ICOS TMPRSS13

3.88e-041723731aecc98a3eadabae0f1f328091a9733d916017ec
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

NEB ZBED4 NOS3

3.94e-0417337342c911ed16fabdabef063830e8407192d8bde950
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLK8 ICOS TMPRSS13

3.94e-0417337315a77f6aac968b7a1afea4f60aedbb95b9d0f765
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ICOS NEB TMPRSS13

4.01e-0417437333386750842c47ad7e7286d0f26a556da1a2de02
ToppCellfacs-Lung-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MED24 ICOS TMPRSS13

4.01e-041743731c073177c1753e3b91ef8fd9e95230a1d13c82f3
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-regulatory_T_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ICOS NEB TMPRSS13

4.01e-041743739344d4e76d7d9429aea87d3c0b98246200d16014
ToppCellfacs-Lung-nan-3m-Lymphocytic-CD8+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MED24 ICOS TMPRSS13

4.01e-041743735491ad5c144baf2ef9b1c58eb720c872d14feb15
ToppCellNS-moderate-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TMPRSS13 NXPH2 WNT11

4.08e-04175373a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ICOS NEB TMPRSS13

4.08e-041753739de288c338cee67be0e9b836c87799bbc1db1c38
ToppCellNS-moderate-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TMPRSS13 NXPH2 WNT11

4.22e-0417737399500aed584f793aaf308f8afbf5d1c6a9b4ee55
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLK8 ICOS NEB

4.22e-0417737336da06ca9577cdb7c7b5114e604f6546b9765c08
ToppCell10x3'2.3-week_17-19-Lymphocytic_T-T_NK-NK_T_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ICOS PTCH1 NOS3

4.29e-04178373a34bb693b72684cbd97ac9efff77d2d14e41be75
ToppCellNS-moderate-d_16-33-Epithelial-Ionocyte|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NXPH2 TNFRSF11B WNT11

4.43e-041803738af8b4af2dc72223ac71fc027e0d4280c5dd81f8
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BMP1 TNFRSF11B WNT11

4.43e-04180373c4068fe47408cfd899131a85fa4b7e5908926f94
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BMP1 PIGB NOS3

4.50e-04181373136b0c60680068838d184d32aa99d7bea8718dbc
ToppCelldroplet-Marrow-BM-1m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF10 COP1 MPND

4.50e-0418137389c551de26de047c316c91ac1d97bdf728a33d9e
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-Ionocyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IGSF1 TMPRSS13 NXPH2

4.57e-041823736e7dac78dc030f74e546b9f6db07556e9bb13ac2
ToppCellcellseq-Epithelial-Epithelial_Neuro-Secretory-Ionocyte-Ionocyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IGSF1 TMPRSS13 NXPH2

4.57e-04182373cd972d30519db706477c6b0c901165b81b74abed
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_3|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

IGSF1 PTCH1 WNT11

4.65e-04183373f4ea7113ce9099222743d9ff02388d3d8a9e987b
ToppCelldroplet-Marrow-BM-1m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF10 COP1 MPND

4.72e-0418437369348c9237e44f7752ac01f60e733ad41580fdb8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LLGL2 NRK TNFRSF11B

4.72e-04184373d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-CD45____T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLK8 ICOS NEB

4.72e-041843732c8e9ddce3e60302965dcf9dee77c4fe33e4071d
ToppCellfacs-Heart-LA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCAF2 LLGL2 TMPRSS13

4.87e-04186373246503fd4e6ae24041c606b069eb5fb313e60f73
ToppCellfacs-Heart-LA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCAF2 LLGL2 TMPRSS13

4.87e-04186373ef93ac469eb4f63db036f14b442c1503b8c6de38
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

IGSF1 PTCH1 WNT11

4.95e-04187373387cb27c8a20031cd87381a9e1172f1f62e1488b
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEB TMPRSS13 NXPH2

5.02e-041883731f912ea015f50570e848259d948a0ba682d64bb4
ToppCellwk_08-11-Mesenchymal-Mesothelial-Early_mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

KLK8 SLC5A12 NXPH2

5.02e-041883736151051c027c7ff7d5d4bf5f1e11d7fe58eb22ed
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GYG2 IGSF1 NEB

5.02e-04188373b01cb642f8b2d83235706fec7477c15005094161
ToppCellmoderate-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NXPH2 TNFRSF11B WNT11

5.10e-041893736011b747e27d61d222380a7bffdd921a68e9b657
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

IGSF1 PTCH1 WNT11

5.10e-04189373f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LLGL2 NRK TNFRSF11B

5.10e-04189373e059be2965cca70ff5576df055d0af1775b76e00
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

IGSF1 PTCH1 WNT11

5.10e-041893730abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

IGSF1 PTCH1 WNT11

5.18e-04190373d24af6af3271e34afab744352afd28be8a7cc5c3
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BMP1 TCAF2 NOS3

5.18e-041903733cf464664d6aa22b212e60b70885953887e92483
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

IGSF1 PTCH1 WNT11

5.18e-0419037371a00f63fdd4eb4cc6f190d37e7a0417cdaafacb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LLGL2 DNAH14 TNFRSF11B

5.18e-041903733fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellCOVID-19-Heart-CM_4|Heart / Disease (COVID-19 only), tissue and cell type

RNF10 POPDC2 TNFRSF11B

5.18e-041903733729648a17093b438398b82e32bbccc3af7b8c5d
ToppCellcontrol-Myeloid-Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

COP1 JMJD1C ADGRE3

5.26e-04191373db1b3cd07d7d190155b2d14e82e1d124975fbd0b
ToppCell18-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

IGSF1 PTCH1 WNT11

5.26e-0419137386ce98d2c90c196474b06869de888cf5d1eed196
ToppCellControl-Lymphoid-T|World / Disease state, Lineage and Cell class

TCAF2 ICOS ZBED4

5.34e-04192373253cf4d2cf88ad8c45b73779336180840bef054b
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

IGSF1 PTCH1 WNT11

5.34e-04192373c4efc170852abbcf0c53c2b0f8a0cc9fe7f116c8
ToppCell343B-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

LLGL2 MPND ACADSB

5.34e-04192373445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NEB NRK WNT11

5.34e-04192373ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

IGSF1 PTCH1 WNT11

5.34e-041923734c9d748f209cc1e13d28c8c7f5180ab8522e0fbf
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TCAF2 NOS3 TNFRSF11B

5.42e-04193373c0f0052c24b7fe9e21d2bc6c38047a8e755f87b6
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-goblet|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HIP1R LLGL2 TNFRSF11B

5.42e-04193373402aad2f9e789ad1f2e1536cdc9ce61de7625427
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TCAF2 NOS3 TNFRSF11B

5.42e-04193373682ce63b73a7d02eef240673db67058d7507f744
ToppCellControl-Lymphoid-T|Control / Disease state, Lineage and Cell class

TCAF2 ICOS ZBED4

5.42e-04193373af928046ccd1ca874be1534aef6ca7f27d90bc46
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEB TNFRSF11B WNT11

5.42e-041933735bee7abc550ddaa28cbb3b9ecaf6b924ab175de0
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

IGSF1 PTCH1 WNT11

5.42e-041933732f203f6f0c2135acb046c9351a633c3b5b254a46
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HIP1R LLGL2 TNFRSF11B

5.42e-041933737ee3b1ef5c455f321b4e154ae62c69543fe9b30e
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LLGL2 TMPRSS13 NXPH2

5.51e-04194373ea5b7727ffef6cb454c501979a51bc1d4108d0e4
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TCAF2 NOS3 TNFRSF11B

5.59e-0419537353b83e16b350100b1d5791a9c42bd98e37cbc0af
ToppCelldroplet-Marrow-BM-1m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF10 COP1 MPND

5.59e-04195373637b06ef3967b03f7165d102d316e8b7161a817d
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW12-Neuronal-GABAergic_neurons|GW12 / Sample Type, Dataset, Time_group, and Cell type.

PIGB MPND NXPH2

5.59e-04195373efdea22118d5be46c5abfe8e3fbe39503390665d
ToppCell15-Distal-Mesenchymal-Airway_Smooth_Muscle|Distal / Age, Tissue, Lineage and Cell class

IGSF1 PTCH1 WNT11

5.67e-041963730e45817625b96d21a8cc4dfbbd465ee6403b6802
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TMPRSS13 NXPH2 WNT11

5.67e-0419637395544097577f20ed7f4144bd940471cde0617554
ToppCellproximal-Epithelial-Ionocyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IGSF1 TMPRSS13 NXPH2

5.76e-04197373e5d5accefaacea5ed2e22f906f5bcbc75083f287
ToppCellproximal-mesenchymal-Myofibroblast|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PTCH1 NRK WNT11

5.76e-04197373ab21baea931ff134cf5a7ee369c091230988108b
ToppCellproximal-mesenchymal-Myofibroblast-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PTCH1 NRK WNT11

5.76e-0419737315f2f169758a07143fc7d1bdb58d0b4d750a0be4
ToppCellParenchymal-10x5prime-Stromal-Mesofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KLK8 NRK TNFRSF11B

5.76e-0419737388a86286b9c3ea3b076d7464faec42d0392ee7f8
ToppCellParenchymal-10x5prime-Stromal-Mesofibroblastic-Mesothelia|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KLK8 NRK TNFRSF11B

5.76e-041973732773d2eb5f232a7e49da116efffcb6bf5eb90810
ToppCellproximal-Epithelial-Ionocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IGSF1 TMPRSS13 NXPH2

5.76e-04197373f65c35761da7c168d5c6e4d7edf5dafa26652fe4
ToppCellproximal-3-Epithelial-Ionocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IGSF1 TMPRSS13 NXPH2

5.76e-04197373288492fc67d8e81349d38e82caf1f1890276b299
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

BMP1 GYG2 TNFRSF11B

5.76e-041973732ca5ebb708935a90b12b8e98a22ae2d664ed002e
ToppCellproximal-3-mesenchymal-Myofibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PTCH1 NRK WNT11

5.76e-04197373c59b64674fb4aaa945c1df7e4a9a3605c7cd2b75
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KLK8 ICOS TMPRSS13

5.76e-041973739ee927d005eb17843e2516c8006eb192c6ad2af8
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KLK8 ICOS TMPRSS13

5.84e-041983733371276410dba693c238b383d990b89371b14d8d
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

IGSF1 NEB NRK

5.84e-0419837355e583321f60c95898d93cd0d2615c6692db52ec
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

BMP1 PTCH1 NRK

5.84e-041983730c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BMP1 LLGL2 DNAH14

5.93e-041993738587bd98de7767a575088afbea07a1feb4516b9b
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

IGSF1 NEB NRK

5.93e-04199373e19b296d583f8bad3b66ee998a8153634d6fe09e
ToppCellBiopsy_Control_(H.)-Mesenchymal-Mesothelial_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

KLK8 NRK TNFRSF11B

5.93e-04199373ca970114b5aef4518ce580897a62ac88688b2671
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

IGSF1 NEB NRK

5.93e-04199373801887db51ac5dc5b068808ff75e3a46643398e9
DiseaseUremia

NOS3 TNFRSF11B

1.95e-0417362C0041948
Diseasemacrophage inflammatory protein 1a measurement

SLC5A12 ICOS

7.01e-0432362EFO_0008218
DiseaseCleft upper lip

PTCH1 NOS3

1.04e-0339362C0008924
DiseaseCleft palate, isolated

PTCH1 NOS3

1.21e-0342362C1837218
Diseasecolitis (biomarker_via_orthology)

ICOS NOS3

1.21e-0342362DOID:0060180 (biomarker_via_orthology)
Diseasefeeling emotionally hurt measurement

ICOS PTCH1

2.14e-0356362EFO_0009599

Protein segments in the cluster

PeptideGeneStartEntry
SKISCISWSSYHKNL

COP1

471

Q8NHY2
KGTSAYCSAWKPLLL

ATG4A

211

Q8WYN0
TCLSSWKIPPHVSKS

ACADSB

21

P45954
KYPSKKECTWAISST

BMP1

766

P13497
TQSHVSWLCSKPFKV

NXPH2

216

O95156
AWSHFLLTYKPKCLG

MDN1

2146

Q9NU22
TYLKDSSRHCPSLWA

LLGL2

721

Q6P1M3
SSSAYTPLKCILKHW

NCR3LG1

291

Q68D85
NKLYSDIPHSWICEK

JMJD1C

2151

Q15652
HLSPESSRKAYCKTW

KIAA1109

4306

Q2LD37
LLTSWKIGVYSPVHC

IFNAR1

206

P17181
SPHWFYCKIIDSKET

DDHD2

41

O94830
FNSPSAWATHCKKLV

MPND

121

Q8N594
PLSLKYSCPSESTWK

MON2

1446

Q7Z3U7
KSHQTWTFALTCKPA

HELZ

276

P42694
LHYGVCSTWLSQLKP

NOS3

971

P29474
ICWLTKKKYSSSVHD

ICOS

161

Q9Y6W8
TLTKLHCWTLTHYSK

GYG2

116

O15488
LPSSSILSWKFCHVL

HIP1R

76

O75146
SCHYLLTWKTSIRMP

IGSF1

391

Q8N6C5
TLWQKHAYRSCKPLS

DNAH14

3246

Q0VDD8
SVYLSTKKPPSHWIT

DNAH14

3481

Q0VDD8
NWVLTAAHCKKPKYT

KLK8

66

O60259
LSLWSIKTPSHIFCT

SDIM1

41

Q6ZPB5
ALKSSIHLYAWAPKS

NRK

1331

Q7Z2Y5
YSLTHLKTWKKPALS

PIGB

376

Q92521
PSFTKSLCRESHWKC

TMEM151B

51

Q8IW70
WTCSSSLYPSKHPIT

TCAF2

516

A6NFQ2
KLAVWCALSSYSSHK

MED24

811

O75448
PCTKWTLSSFAEKHY

PTCH1

726

Q13635
TPSTKKVFCVYWKST

ADGRE3

296

Q9BY15
PGTYLKQHCTAKWKT

TNFRSF11B

46

O00300
LKIYSGSSHQWLPIC

TMPRSS13

236

Q9BYE2
HYLSLSEKTWSKCPI

RNF10

251

Q8N5U6
KYSTSLSWIHLLKPL

TBC1D23

121

Q9NUY8
ETSCSYISWPRKSLH

POPDC2

206

Q9HBU9
VCYGIKWLALSKTPS

WNT11

21

O96014
KSCFPHLSDKLSTWI

SLC5A12

366

Q1EHB4
HSCDPLTYWNLKKAS

ZBED4

1096

O75132
CYVWDTPQILHAKKS

NEB

4611

P20929