Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	keratohyalin granule	FLG HRNR	5.81e-05	5	51	2	GO:0036457
HumanPheno	Abnormal fear-induced behavior	TNIK BPTF BMPR1A SETBP1 MAMLD1 SMARCE1 THOC2 HNRNPA1 NIPBL	4.28e-06	538	15	9	HP:0100852
Domain	Cadherin_tail	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	2.59e-06	37	49	4	PF15974
Domain	Cadherin_CBD	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	2.59e-06	37	49	4	IPR031904
Domain	Cadherin_C_2	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	4.35e-06	42	49	4	PF16492
Domain	Cadherin_C	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	4.35e-06	42	49	4	IPR032455
Domain	Cadherin_N	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	2.52e-05	65	49	4	IPR013164
Domain	Cadherin_2	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	2.52e-05	65	49	4	PF08266
Domain	Cadherin_CS	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	1.90e-04	109	49	4	IPR020894
Domain	Cadherin	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	2.18e-04	113	49	4	PF00028
Domain	CADHERIN_1	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	2.18e-04	113	49	4	PS00232
Domain	CADHERIN_2	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	2.26e-04	114	49	4	PS50268
Domain	-	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	2.26e-04	114	49	4	2.60.40.60
Domain	CA	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	2.33e-04	115	49	4	SM00112
Domain	Cadherin-like	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	2.41e-04	116	49	4	IPR015919
Domain	Cadherin	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	2.58e-04	118	49	4	IPR002126
Domain	S100_CABP	FLG HRNR	2.27e-03	27	49	2	PS00303
Domain	S_100	FLG HRNR	2.27e-03	27	49	2	PF01023
Domain	S100_Ca-bd_sub	FLG HRNR	2.44e-03	28	49	2	IPR013787
Domain	S100/CaBP-9k_CS	FLG HRNR	2.44e-03	28	49	2	IPR001751
Domain	S_100	FLG HRNR	2.44e-03	28	49	2	SM01394
Domain	UBA	UBQLN1 SNRK	5.95e-03	44	49	2	IPR015940
Domain	UBA	UBQLN1 SNRK	6.76e-03	47	49	2	PS50030
Domain	Zinc_finger_PHD-type_CS	BPTF INTS12	1.26e-02	65	49	2	IPR019786
Domain	Homeobox_CS	LMX1A POU2F2 PBX3	1.28e-02	186	49	3	IPR017970
Domain	USP_CS	USP36 USP4	1.30e-02	66	49	2	IPR018200
Domain	LIM	LIMD1 LMX1A	1.41e-02	69	49	2	PF00412
Domain	-	LIMD1 LMX1A	1.45e-02	70	49	2	2.10.110.10
Domain	USP_1	USP36 USP4	1.45e-02	70	49	2	PS00972
Domain	LIM_DOMAIN_2	LIMD1 LMX1A	1.49e-02	71	49	2	PS50023
Domain	Znf_LIM	LIMD1 LMX1A	1.49e-02	71	49	2	IPR001781
Domain	LIM_DOMAIN_1	LIMD1 LMX1A	1.49e-02	71	49	2	PS00478
Domain	UCH	USP36 USP4	1.49e-02	71	49	2	PF00443
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	BPTF ZNF608 SMARCE1 MED1 NIPBL	1.63e-07	83	52	5	28794006
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	BPTF INTS12 LIMD1 LMX1A KCMF1 POU2F2 SMARCE1 PBX3 ZC3H6 PHC1	2.84e-07	808	52	10	20412781
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	BPTF NOL4L UBQLN1 INTS12 UBR5 SMARCE1 RAD54L2 MED1 THOC2 HNRNPA1 NIPBL	5.70e-07	1103	52	11	34189442
Pubmed	Human transcription factor protein interaction networks.	FLG BPTF NOL4L INTS12 LIMD1 ZNF608 KCMF1 SMARCE1 RAD54L2 HRNR NIPBL DCAF5	9.92e-07	1429	52	12	35140242
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	FLG BPTF BMPR1A INTS12 PCDHGC5 PCDHGB7 ZNF608 PCDHGB3 RAD54L2 HNRNPA1 PCDHGC3 NIPBL	1.09e-06	1442	52	12	35575683
Pubmed	Atopic Dermatitis Susceptibility Variants in Filaggrin Hitchhike Hornerin Selective Sweep.	FLG HRNR	2.19e-06	2	52	2	27678121
Pubmed	Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	3.37e-06	68	52	4	11230163
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	POM121 UBQLN1 TSPOAP1 SETBP1 RAD54L2 HRNR WTAP	3.48e-06	430	52	7	35044719
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	FLG BPTF SMARCE1 HRNR MED1 THOC2 ZC3H6 HNRNPA1 NIPBL WTAP	3.93e-06	1082	52	10	38697112
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	4.24e-06	72	52	4	10380929
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	4.73e-06	74	52	4	10817752
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	UBR5 SMARCE1 RAD54L2 MED1 THOC2 WTAP PHC1	4.90e-06	453	52	7	29656893
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	5.55e-06	77	52	4	10835267
Pubmed	Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration.	UBQLN1 UBR5 KCMF1 DCAF5	6.14e-06	79	52	4	27325702
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	6.46e-06	80	52	4	10716726
Pubmed	Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin.	FLG HRNR	6.57e-06	3	52	2	23403047
Pubmed	POM121 inhibits the macrophage inflammatory response by impacting NF-κB P65 nuclear accumulation.	POM121 POM121B	6.57e-06	3	52	2	30802453
Pubmed	The role of frontotemporal dementia associated genes in patients with Alzheimer's disease.	UBQLN1 HNRNPA1	6.57e-06	3	52	2	34172279
Pubmed	Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.	POM121 POM121B	6.57e-06	3	52	2	35507432
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	FLG CROCC2 RBMS2 USP4 ZC3H6 DCAF5 WTAP PHC1	7.95e-06	689	52	8	36543142
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	USP36 TNIK LIMD1 PAPOLA SMARCE1 MED1 THOC2 HNRNPA1 NIPBL	9.13e-06	934	52	9	33916271
Pubmed	Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes.	POM121 POM121B	1.31e-05	4	52	2	17900573
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	BMPR1A UBQLN1 PAPOLA ZNF608 KCMF1 MED1 THOC2 ZC3H6 HNRNPA1 WTAP	1.36e-05	1247	52	10	27684187
Pubmed	Interaction network of human early embryonic transcription factors.	BPTF ZNF608 SMARCE1 RAD54L2 HRNR NIPBL	1.39e-05	351	52	6	38297188
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	BPTF SMARCE1 MED1 THOC2 NIPBL PHC1 NOS1AP	1.41e-05	533	52	7	30554943
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FILIP1 BPTF NOL4L PAPOLA MED1 THOC2 NIPBL WTAP	1.84e-05	774	52	8	15302935
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	TNIK LIMD1 UBR5 RBMS2 KCMF1 SMARCE1 SNRK HNRNPA1 NOS1AP	2.11e-05	1038	52	9	26673895
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	TNIK ZNF608 UBR5 SETBP1 SNRK	2.20e-05	225	52	5	12168954
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TNIK UBR5 TSPOAP1 NAV3 DCAF5 NOS1AP	3.20e-05	407	52	6	12693553
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	BPTF SMARCE1 MED1 PBX3 HNRNPA1 PHC1	3.38e-05	411	52	6	35182466
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	USP36 BPTF BMPR1A ZNF608 UBR5 SMARCE1 TUBGCP5 DCAF5 NOS1AP	3.71e-05	1116	52	9	31753913
Pubmed	Differential expression of individual gamma-protocadherins during mouse brain development.	PCDHGC5 PCDHGC3	4.58e-05	7	52	2	15964765
Pubmed	Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.	LIMD1 LMX1A POU2F2 PBX3 PHC1	4.63e-05	263	52	5	20932939
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	ZNF608 TTLL5 KCMF1 MED1 THOC2 WTAP PHC1	4.74e-05	645	52	7	25281560
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	INTS12 ZNF608 SMARCE1 MED1 NIPBL	5.06e-05	268	52	5	33640491
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	USP36 BPTF MED1 THOC2 HNRNPA1	5.33e-05	271	52	5	32433965
Pubmed	EGFR suppresses p53 function by promoting p53 binding to DNA-PKcs: a noncanonical regulatory axis between EGFR and wild-type p53 in glioblastoma.	ZNF608 HRNR PHC1	7.41e-05	54	52	3	35474131
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	USP36 BPTF RBMS2 SMARCE1 MED1 THOC2 HNRNPA1 NIPBL	8.04e-05	954	52	8	36373674
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	UBQLN1 TTLL5 NAV3 SMARCE1 RAD54L2 PBX3 TUBGCP5 NIPBL DCAF5	1.10e-04	1285	52	9	35914814
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	PCDHGC5 PAPOLA SETBP1 HRNR TUBGCP5 HNRNPA1	1.15e-04	513	52	6	25798074
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	USP36 BPTF INTS12 SMARCE1 MED1 THOC2 HNRNPA1 NIPBL WTAP	1.16e-04	1294	52	9	30804502
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	BPTF SMARCE1 MED1 PHC1	1.16e-04	167	52	4	20362541
Pubmed	A neurogenomics approach to gene expression analysis in the developing brain.	BMPR1A SNRK THOC2 HNRNPA1	1.24e-04	170	52	4	15582152
Pubmed	LncRNA SAMD12-AS1 promotes cell proliferation and inhibits apoptosis by interacting with NPM1.	FLG HRNR	1.43e-04	12	52	2	31406141
Pubmed	BMI1-UBR5 axis regulates transcriptional repression at damaged chromatin.	UBR5 PHC1	1.69e-04	13	52	2	27647897
Pubmed	PRDM14 directly interacts with heat shock proteins HSP90α and glucose-regulated protein 78.	FLG HRNR	1.97e-04	14	52	2	29178343
Pubmed	Maturation of postnatally generated olfactory bulb granule cells depends on functional γ-protocadherin expression.	PCDHGC5 PCDHGC3	2.27e-04	15	52	2	23515096
Pubmed	Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.	POM121 POM121B	2.27e-04	15	52	2	14697343
Pubmed	Bmp5/7 in concert with the mid-hindbrain organizer control development of noradrenergic locus coeruleus neurons.	BMPR1A LMX1A	2.60e-04	16	52	2	20493948
Pubmed	Mutations in Hnrnpa1 cause congenital heart defects.	BMPR1A HNRNPA1	2.60e-04	16	52	2	29367466
Pubmed	TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN.	FLG BPTF NAV3 HRNR HNRNPA1	2.65e-04	382	52	5	37249651
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	BPTF INTS12 UBR5 POU2F2 SMARCE1 HRNR PBX3	2.74e-04	857	52	7	25609649
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	UBQLN1 UBR5 RBMS2 KCMF1 USP4 MED1	2.77e-04	604	52	6	38803224
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	BPTF INTS12 SMARCE1 MED1 NIPBL PHC1	2.86e-04	608	52	6	36089195
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	BPTF INTS12 NIPBL	2.96e-04	86	52	3	37253089
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	BPTF UBR5 HDHD5 KCMF1 PHC1	3.12e-04	396	52	5	26687479
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	UBQLN1 LIMD1 SMARCE1 MED1 HNRNPA1	3.23e-04	399	52	5	35987950
Pubmed	TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis.	FLG UBR5	3.30e-04	18	52	2	32924931
Pubmed	Analyses with double knockouts of the Bmpr1a and Bmpr1b genes demonstrate that BMP signaling is involved in the formation of precerebellar mossy fiber nuclei derived from the rhombic lip.	BMPR1A LMX1A	3.30e-04	18	52	2	31869353
Pubmed	Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling.	BMPR1A LIMD1 PBX3	3.49e-04	91	52	3	21194568
Pubmed	A conserved acetylation switch enables pharmacological control of tubby-like protein stability.	LIMD1 UBR5 RAD54L2 DCAF5	3.50e-04	223	52	4	33187986
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	FLG UBR5 SMARCE1 HRNR TUBGCP5 HNRNPA1	3.73e-04	639	52	6	23443559
Pubmed	Variation in genes of the epidermal differentiation complex in German atopic dermatitis patients.	FLG HRNR	4.52e-04	21	52	2	19601998
Pubmed	A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis.	USP36 NOL4L RBMS2 HNRNPA1	5.71e-04	254	52	4	28431233
Pubmed	SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.	USP36 MED1 NIPBL PHC1	6.14e-04	259	52	4	30404004
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	LIMD1 LMX1A POU2F2 SMARCE1 PBX3 PHC1	6.45e-04	709	52	6	22988430
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	USP36 LIMD1 RBMS2 MED1 HNRNPA1 NOS1AP	7.19e-04	724	52	6	36232890
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	NOL4L UBR5 KCMF1 MED1 TUBGCP5 HNRNPA1 SLC23A1 NIPBL	7.43e-04	1327	52	8	32694731
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	BPTF PAPOLA UBR5 SMARCE1 MED1 THOC2 NIPBL	7.48e-04	1014	52	7	32416067
Pubmed	In Vitro Identification of Histatin 5 Salivary Complexes.	FLG HRNR	7.51e-04	27	52	2	26544073
Pubmed	Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.	BPTF UBR5 NIPBL	7.64e-04	119	52	3	23508102
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	BPTF POM121 UBR5 HRNR THOC2 HNRNPA1 NIPBL	7.92e-04	1024	52	7	24711643
Pubmed	A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells.	POM121 PAPOLA HNRNPA1	8.02e-04	121	52	3	22412018
Pubmed	Cul3-KLHL20 E3 ubiquitin ligase plays a key role in the arms race between HIV-1 Nef and host SERINC5 restriction.	UBR5 KCMF1	8.08e-04	28	52	2	35474067
Pubmed	Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.	PCDHGC5 PCDHGC3	8.08e-04	28	52	2	15347688
Pubmed	Mediator and cohesin connect gene expression and chromatin architecture.	MED1 NIPBL	8.08e-04	28	52	2	20720539
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	BPTF PAPOLA MED1 THOC2	8.55e-04	283	52	4	30585729
Pubmed	Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.	BPTF HNRNPA1 NIPBL	8.61e-04	124	52	3	20850016
Pubmed	The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing.	POM121 NIPBL	8.67e-04	29	52	2	17577209
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	UBQLN1 UBR5 KCMF1 HNRNPA1	9.12e-04	288	52	4	23383273
Pubmed	Tangential Intrahypothalamic Migration of the Mouse Ventral Premamillary Nucleus and Fgf8 Signaling.	LMX1A PBX3	9.92e-04	31	52	2	34095148
Pubmed	Specification of dopaminergic subsets involves interplay of En1 and Pitx3.	LMX1A PBX3	9.92e-04	31	52	2	23863478
Pubmed	Ubiquitin-specific peptidase 2a (USP2a) deubiquitinates and stabilizes β-catenin.	USP36 USP4	1.12e-03	33	52	2	30323974
Pubmed	Functional significance of isoform diversification in the protocadherin gamma gene cluster.	PCDHGC5 PCDHGC3	1.19e-03	34	52	2	22884324
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	UBQLN1 UBR5 HDHD5 THOC2 WTAP	1.20e-03	534	52	5	35032548
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	BPTF C10orf143 BMPR1A KCMF1 NIPBL	1.22e-03	536	52	5	15840001
Pubmed	Large-scale analysis of the human ubiquitin-related proteome.	UBQLN1 USP4 TUBGCP5 DCAF5	1.24e-03	313	52	4	16196087
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	BPTF C10orf143 BMPR1A KCMF1 NIPBL	1.24e-03	538	52	5	10512203
Pubmed	Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors.	SMARCE1 PHC1	1.26e-03	35	52	2	22325351
Pubmed	Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase.	UBR5 DCAF5	1.26e-03	35	52	2	19287380
Pubmed	Fine-scale comparative mapping of the human 7q11.23 region and the orthologous region on mouse chromosome 5G: the low-copy repeats that flank the Williams-Beuren syndrome deletion arose at breakpoint sites of an evolutionary inversion(s).	POM121 POM121B	1.26e-03	35	52	2	11013070
Pubmed	Thioredoxin interacting protein (Txnip) forms redox sensitive high molecular weight nucleoprotein complexes.	FLG HRNR	1.34e-03	36	52	2	31669268
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	BPTF LIMD1 SMARCE1 MED1 THOC2	1.36e-03	549	52	5	38280479
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	USP36 UBR5 USP4	1.40e-03	147	52	3	29576527
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	BPTF SMARCE1 NIPBL	1.49e-03	150	52	3	28242625
Pubmed	Peering through the pore: nuclear pore complex structure, assembly, and function.	POM121 POM121B	1.49e-03	38	52	2	12791264
Pubmed	Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells.	BPTF BMPR1A	1.49e-03	38	52	2	18974875
Pubmed	Generation and comparative analysis of approximately 3.3 Mb of mouse genomic sequence orthologous to the region of human chromosome 7q11.23 implicated in Williams syndrome.	POM121 POM121B	1.49e-03	38	52	2	11779826
Pubmed	Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline.	BMPR1A LMX1A	1.49e-03	38	52	2	18579678
Interaction	TFIP11 interactions	POM121 UBR5 SMARCE1 USP4 MED1 PBX3 THOC2 HNRNPA1	1.09e-05	427	51	8	int:TFIP11
Interaction	LMNB1 interactions	USP36 TNIK BMPR1A POM121 UBQLN1 RAD54L2 THOC2 HNRNPA1 NIPBL	1.96e-05	610	51	9	int:LMNB1
Interaction	ERG interactions	ZNF608 UBR5 SMARCE1 RAD54L2 HNRNPA1 NIPBL	2.04e-05	223	51	6	int:ERG
Interaction	CEBPA interactions	BPTF NOL4L UBQLN1 INTS12 UBR5 SMARCE1 RAD54L2 MED1 THOC2 HNRNPA1 NIPBL WTAP	4.90e-05	1245	51	12	int:CEBPA
Interaction	PGR interactions	BPTF UBR5 POU2F2 SMARCE1	6.04e-05	84	51	4	int:PGR
Interaction	HNF4A interactions	BPTF ZNF608 SMARCE1 RAD54L2 MED1 NIPBL	6.58e-05	275	51	6	int:HNF4A
Interaction	MDK interactions	UBQLN1 KCMF1 PBX3 NOS1AP	8.26e-05	91	51	4	int:MDK
Interaction	PCDHGA4 interactions	POM121 PCDHGB7 PCDHGC3	8.64e-05	34	51	3	int:PCDHGA4
Cytoband	Ensembl 112 genes in cytogenetic band chr5q31	PCDHGC5 PCDHGB7 PCDHGB3 NRG2 PCDHGC3 SLC23A1	1.13e-06	298	52	6	chr5q31
Cytoband	5q31	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	9.22e-06	115	52	4	5q31
Cytoband	3p21.3	LIMD1 USP4	2.07e-03	59	52	2	3p21.3
Cytoband	7q11.23	POM121 POM121B	5.47e-03	97	52	2	7q11.23
Cytoband	Ensembl 112 genes in cytogenetic band chr3p21	LIMD1 USP4 RAD54L2	5.56e-03	316	52	3	chr3p21
GeneFamily	Clustered protocadherins	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	6.11e-06	64	34	4	20
GeneFamily	EF-hand domain containing\|S100 fused type protein family	FLG HRNR	7.17e-05	7	34	2	1350
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	BPTF SMARCE1 MED1 THOC2 NIPBL	3.53e-06	199	52	5	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	BPTF ZNF608 UBR5 SNRK NIPBL	3.62e-06	200	52	5	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
Computational	Neighborhood of RBBP6	BPTF PAPOLA THOC2 HNRNPA1	3.00e-05	70	28	4	GNF2_RBBP6
Drug	Mifepristone [84371-65-3]; Down 200; 9.4uM; PC3; HT_HG-U133A	TNIK DNAH3 RBMS2 NAV3 NRG2 NIPBL	4.92e-06	196	51	6	5827_DN
Disease	childhood trauma measurement, alcohol consumption measurement	PCDHGC5 PCDHGB7 PCDHGB3 PCDHGC3	7.06e-06	71	51	4	EFO_0007878, EFO_0007979
Disease	mean platelet volume	NOL4L PCDHGC5 PCDHGB7 PCDHGB3 SETBP1 HNRNPA1 PCDHGC3 DCAF5 NOS1AP	5.61e-05	1020	51	9	EFO_0004584
Disease	gastroesophageal reflux disease	NAV3 SNRK PBX3	7.19e-04	101	51	3	EFO_0003948
Disease	neuroimaging measurement, brain volume measurement	TNIK BPTF NAV3 POU2F2	1.51e-03	286	51	4	EFO_0004346, EFO_0006930
Disease	macrophage inflammatory protein 1b measurement	SNRK USP4 RAD54L2	1.70e-03	136	51	3	EFO_0008219
Disease	Craniofacial Abnormalities	BMPR1A SETBP1 NIPBL	2.51e-03	156	51	3	C0376634
Disease	childhood onset asthma	FLG SMARCE1 HRNR MED1	2.65e-03	334	51	4	MONDO_0005405
Disease	neutrophil measurement	TSPOAP1 HNRNPA1 SLC23A1	3.58e-03	177	51	3	EFO_0803548
Disease	substance-related disorder	NOL4L USP4	3.68e-03	52	51	2	MONDO_0002494
Disease	eosinophil count	BPTF DNAH3 NOL4L POU2F2 SMARCE1 THOC2 HNRNPA1 PHC1	3.78e-03	1488	51	8	EFO_0004842
Disease	white matter microstructure measurement	TNIK BPTF SETBP1 PBX3	4.60e-03	390	51	4	EFO_0005674
Disease	atopic asthma	FLG SMARCE1 MED1	4.96e-03	199	51	3	EFO_0010638

Protein segments in the cluster

Peptide	Gene	Start	Entry
NNDSPGSGSQSGRKA	ARHGEF26	181	Q96DR7
GQSSGPRTSRNQGSS	FLG	606	P20930
GQGQSSGPRTSRNQG	FLG	1901	P20930
SGQGQSAGPRTSRNQ	FLG	3521	P20930
SGSQGPSCESTSNGR	RAD54L2	1136	Q9Y4B4
IRPNTSGSGGTTSNS	BPTF	2161	Q12830
PSNSTPNSSSGSNGN	RBMS2	36	Q15434
GSSSGGQSSVGRSQP	TSPOAP1	751	O95153
SSLVPGSSSQLSGNG	INTS12	391	Q96CB8
GSSSQLSGNGNSGTS	INTS12	396	Q96CB8
SQAQRPGTSGSQNGD	PCDHGB7	816	Q9Y5F8
NQTNSPTTPNSGSSG	PBX3	326	P40426
SSRSSEGSLGGQNSG	LIMD1	236	Q9UGP4
NTQRLSSAQTNGGGS	LMX1A	266	Q8TE12
SQAQRPGTSGSQNGD	PCDHGC5	831	Q9Y5F6
FNSGLNSGGSTNSSP	NAV3	426	Q8IVL0
QGLVPAGGSSSNSTR	NRG2	136	O14511
SSRYGQQGSGSGQSP	HRNR	646	Q86YZ3
SSSYGQQGSGSGQSP	HRNR	1816	Q86YZ3
SSSYGQQGSGSGQSP	HRNR	2286	Q86YZ3
NRPASQETGSTGNGS	NIPBL	521	Q6KC79
SGSTLNSGSGNCPRT	DCAF5	801	Q96JK2
QGGAGTLPLSQASSS	POU2F2	381	P09086
ASASSGSDQGPSSRQ	TUBGCP5	531	Q96RT8
SQAQRPGTSGSQNGD	PCDHGB3	816	Q9Y5G1
SQAQRPGTSGSQNGD	PCDHGC3	821	Q9UN70
SESGSGNGSSTLNPS	NOL4L	41	Q96MY1
SNSQSTPGSSGQRKR	POM121B	76	A6NF01
PLNSSGSSQGRNSPA	PAPOLA	546	P51003
PRSSGNAATSGNAAT	PAPOLA	626	P51003
NSNSQSTPGSSGQRK	POM121	491	Q96HA1
RTGQGLPSSGNRSSS	DNAH3	141	Q8TD57
GSDSSQALPGQQGTS	CROCC2	1321	H7BZ55
DQSQSSGSGSGLPLL	BMPR1A	211	P36894
SSNTLSGSTLRGSPN	MAMLD1	371	Q13495
RSAGGQLNSSGPSAS	KCMF1	211	Q9P0J7
SRLTNGPSNGSSSRQ	WTAP	271	Q15007
GPSNGSSSRQRTSGS	WTAP	276	Q15007
NSNSSGDPGRQLTGA	NOS1AP	191	O75052
NGTSNSTLSGPGLDS	MED1	976	Q15648
LGGNPGTNSRVTASS	SMARCE1	41	Q969G3
GTQSVSGQDGSSQRP	FILIP1	1141	Q7Z7B0
GAGGTRQQQPSASQS	HDHD5	341	Q9BXW7
RGGSSSYGLQPSNSA	nan	46	Q6P435
PRQSSTSQAGTNQSG	SATL1	361	Q86VE3
GSGGNPTNTSGTTRR	SNRK	611	Q9NRH2
STGISQNGGRSSAQP	C10orf143	76	A0A1B0GUT2
SSQGGSQPGSQAGSS	TNIK	741	Q9UKE5
SGSSDGGTRPSSSQQ	USP4	936	Q13107
SNPGSSQPSGAGTSN	ZC3H6	1001	P61129
STTPKGNSSNGNSGS	THOC2	1246	Q8NI27
GLLGTGNGSTSSSPN	SLC23A1	371	Q9UHI7
GSSGTNGSNATPSEN	UBQLN1	496	Q9UMX0
STNGSSSSGGSSRPQ	PHC1	11	P78364
SVSSGGSGNPNSNST	ZNF608	156	Q9ULD9
PRNQGGYGGSSSSSS	HNRNPA1	351	P09651
TQLGGSNGNLSPAST	SETBP1	781	Q9Y6X0
QGLPGTSNSNSSRSG	USP36	551	Q9P275
NHSSSPGSRSLQTGG	TTLL5	1101	Q6EMB2
SNGPGNRAGSSSSRS	UBR5	971	O95071