Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	thromboxane A2 receptor binding	RPGRIP1 RPGRIP1L	2.01e-05	2	90	2	GO:0031870
GeneOntologyMolecularFunction	prostanoid receptor binding	RPGRIP1 RPGRIP1L	6.01e-05	3	90	2	GO:0031862
GeneOntologyMolecularFunction	ABC-type bile acid transporter activity	ABCC4 ABCC11	1.20e-04	4	90	2	GO:0015432
GeneOntologyMolecularFunction	ATPase-coupled organic acid transmembrane transporter activity	ABCC4 ABCC11	1.20e-04	4	90	2	GO:0033283
GeneOntologyMolecularFunction	ATPase-coupled monocarboxylic acid transmembrane transporter activity	ABCC4 ABCC11	1.20e-04	4	90	2	GO:0033285
GeneOntologyMolecularFunction	ATPase-coupled carboxylic acid transmembrane transporter activity	ABCC4 ABCC11	1.20e-04	4	90	2	GO:0033284
GeneOntologyMolecularFunction	G protein-coupled receptor activity	DRD4 GPR17 FFAR3 GPR42 GPR78 F2RL2 OR10T2 OR10X1 ADRA1D LPAR6 RRH ADGRE1 OR8D4	1.61e-04	884	90	13	GO:0004930
GeneOntologyMolecularFunction	antigen binding	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-5 IGKV1D-39 IGKV1D-12	2.20e-04	190	90	6	GO:0003823
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	DRD4 GPR17 FFAR3 GPR42 GPR78 TMEM63B F2RL2 OR10T2 OR10X1 GHR ADRA1D LPAR6 CD44 RRH ADGRE1 OR8D4	3.28e-04	1353	90	16	GO:0004888
GeneOntologyMolecularFunction	xenobiotic transmembrane transporter activity	ABCC4 ABCC11 SLC22A8	4.79e-04	34	90	3	GO:0042910
GeneOntologyMolecularFunction	ABC-type glutathione S-conjugate transporter activity	ABCC4 ABCC11	5.53e-04	8	90	2	GO:0015431
GeneOntologyMolecularFunction	ATPase-coupled lipid transmembrane transporter activity	ABCC4 ABCC11	7.09e-04	9	90	2	GO:0034040
GeneOntologyMolecularFunction	ATPase-coupled inorganic anion transmembrane transporter activity	ABCC4 ABCC11	8.83e-04	10	90	2	GO:0043225
GeneOntologyMolecularFunction	CCR1 chemokine receptor binding	CCL4L1 CCL4	1.29e-03	12	90	2	GO:0031726
GeneOntologyMolecularFunction	CCR5 chemokine receptor binding	CCL4L1 CCL4	1.52e-03	13	90	2	GO:0031730
GeneOntologyMolecularFunction	prostaglandin transmembrane transporter activity	ABCC4 SLC22A8	1.76e-03	14	90	2	GO:0015132
GeneOntologyMolecularFunction	ABC-type xenobiotic transporter activity	ABCC4 ABCC11	2.03e-03	15	90	2	GO:0008559
GeneOntologyMolecularFunction	icosanoid transmembrane transporter activity	ABCC4 SLC22A8	2.03e-03	15	90	2	GO:0071714
GeneOntologyBiologicalProcess	immunoglobulin production	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 TCIRG1 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-13 IGKV1D-12	4.61e-12	241	94	14	GO:0002377
GeneOntologyBiologicalProcess	production of molecular mediator of immune response	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 FFAR3 GPR42 TCIRG1 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-13 IGKV1D-12	3.84e-11	403	94	16	GO:0002440
GeneOntologyBiologicalProcess	adaptive immune response	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 TCIRG1 IGKV1-5 PRF1 CD44 IGKV1D-43 IGKV1D-39 ADGRE1 IGKV1D-17 IGKV1D-13 IGKV1D-12	2.12e-07	838	94	17	GO:0002250
GeneOntologyBiologicalProcess	bilirubin conjugation	UGT1A4 UGT1A1	2.05e-05	2	94	2	GO:0006789
GeneOntologyBiologicalProcess	positive regulation of acute inflammatory response to non-antigenic stimulus	FFAR3 GPR42	6.15e-05	3	94	2	GO:0002879
GeneOntologyBiologicalProcess	regulation of acute inflammatory response to non-antigenic stimulus	FFAR3 GPR42	1.23e-04	4	94	2	GO:0002877
GeneOntologyBiologicalProcess	amide transport	ABCC4 FFAR3 GPR42 TCIRG1 F2RL2 ADCY8 MADD OSBP SLC22A8	1.28e-04	420	94	9	GO:0042886
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	CCL4L1 DRD4 GPR17 RPGRIP1L FFAR3 GPR42 GPR78 F2RL2 OR10T2 OR10X1 ADCY8 ADRA1D LPAR6 RRH CCL4 ADGRE1 OR8D4	1.71e-04	1395	94	17	GO:0007186
GeneOntologyBiologicalProcess	regulation of protein secretion	DRD4 FFAR3 GPR42 TCIRG1 F2RL2 ADCY8 MADD OSBP	1.99e-04	350	94	8	GO:0050708
GeneOntologyBiologicalProcess	acute inflammatory response to non-antigenic stimulus	FFAR3 GPR42	2.04e-04	5	94	2	GO:0002525
GeneOntologyBiologicalProcess	inflammatory response	CCL4L1 GPR17 FN1 FFAR3 GPR42 TCIRG1 ZEB2 ADCY8 UGT1A1 CD44 CCL4 TBC1D23 KLKB1 PLP1	2.60e-04	1043	94	14	GO:0006954
GeneOntologyBiologicalProcess	regulation of peptide hormone secretion	FFAR3 GPR42 TCIRG1 F2RL2 ADCY8 MADD OSBP	2.76e-04	277	94	7	GO:0090276
GeneOntologyBiologicalProcess	positive regulation of neuronal action potential	FFAR3 GPR42	3.05e-04	6	94	2	GO:1904457
GeneOntologyBiologicalProcess	regulation of peptide transport	FFAR3 GPR42 TCIRG1 F2RL2 ADCY8 MADD OSBP	3.08e-04	282	94	7	GO:0090087
GeneOntologyBiologicalProcess	regulation of peptide secretion	FFAR3 GPR42 TCIRG1 F2RL2 ADCY8 MADD OSBP	3.08e-04	282	94	7	GO:0002791
GeneOntologyBiologicalProcess	positive regulation of MAP kinase activity	DRD4 ERN1 ERN2 ZEB2 GHR	3.11e-04	129	94	5	GO:0043406
GeneOntologyBiologicalProcess	cilium organization	RPGRIP1 ABCC4 RPGRIP1L DYNC2H1 TTLL5 DNAH2 OCRL TBC1D32 TTC17	3.23e-04	476	94	9	GO:0044782
GeneOntologyBiologicalProcess	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	DRD4 FFAR3 GPR42 GPR78 ADCY8 ADRA1D ADGRE1	3.35e-04	286	94	7	GO:0007188
GeneOntologyBiologicalProcess	protein secretion	DRD4 FFAR3 GPR42 TCIRG1 F2RL2 ADCY8 MADD OSBP PRF1	3.43e-04	480	94	9	GO:0009306
GeneOntologyBiologicalProcess	icosanoid transport	ABCC4 DRD4 ABCC11 SLC22A8	3.46e-04	73	94	4	GO:0071715
GeneOntologyBiologicalProcess	establishment of protein localization to extracellular region	DRD4 FFAR3 GPR42 TCIRG1 F2RL2 ADCY8 MADD OSBP PRF1	3.59e-04	483	94	9	GO:0035592
GeneOntologyBiologicalProcess	protein localization to extracellular region	DRD4 FFAR3 GPR42 TCIRG1 F2RL2 ADCY8 MADD OSBP PRF1	3.99e-04	490	94	9	GO:0071692
GeneOntologyBiologicalProcess	retina development in camera-type eye	RPGRIP1 RPGRIP1L DLL4 TTLL5 TCIRG1 TBC1D32	4.11e-04	211	94	6	GO:0060041
GeneOntologyBiologicalProcess	leukotriene transport	ABCC4 ABCC11	4.25e-04	7	94	2	GO:0071716
GeneOntologyBiologicalProcess	non-motile cilium assembly	RPGRIP1 RPGRIP1L DYNC2H1 TBC1D32	4.46e-04	78	94	4	GO:1905515
GeneOntologyBiologicalProcess	acute inflammatory response	FN1 FFAR3 GPR42 UGT1A1 KLKB1	5.00e-04	143	94	5	GO:0002526
GeneOntologyCellularComponent	immunoglobulin complex	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-13 IGKV1D-12	9.31e-13	166	98	13	GO:0019814
GeneOntologyCellularComponent	apical plasma membrane	MGAM ABCC4 FN1 TCIRG1 ABCC11 F2RL2 ADCY8 SLC22A8 CD44 OTOG	9.63e-05	487	98	10	GO:0016324
GeneOntologyCellularComponent	apical part of cell	MGAM ABCC4 FN1 DYNC2H1 TCIRG1 ABCC11 F2RL2 ADCY8 SLC22A8 CD44 OTOG	1.03e-04	592	98	11	GO:0045177
GeneOntologyCellularComponent	IRE1-TRAF2-ASK1 complex	ERN1 ERN2	1.30e-04	4	98	2	GO:1990604
GeneOntologyCellularComponent	blood microparticle	IGKV1-39 IGKV1-17 FN1 IGKV1-5 IGKV1D-12	5.88e-04	144	98	5	GO:0072562
GeneOntologyCellularComponent	9+0 non-motile cilium	RPGRIP1 RPGRIP1L TTLL5 OCRL RRH	7.73e-04	153	98	5	GO:0097731
MousePheno	abnormal single cell response	DRD4 KCNH8 ADCY8 CACNA1G	2.13e-05	35	66	4	MP:0003463
MousePheno	decreased susceptibility to autoimmune diabetes	CCL4L1 GHR PRF1 CCL4	5.84e-05	45	66	4	MP:0004804
MousePheno	abnormal sympathetic neuron innervation pattern	FFAR3 GPR42	6.57e-05	3	66	2	MP:0009284
MousePheno	decreased circulating triiodothyronine level	TG GHR IGSF1	7.80e-05	18	66	3	MP:0005479
Domain	C2-C2_1	RPGRIP1 RPGRIP1L	2.10e-05	2	86	2	PF11618
Domain	RPGRIP1_fam	RPGRIP1 RPGRIP1L	2.10e-05	2	86	2	IPR031139
Domain	C2-C2_1	RPGRIP1 RPGRIP1L	2.10e-05	2	86	2	IPR021656
Domain	7tm_1	DRD4 GPR17 FFAR3 GPR42 GPR78 F2RL2 OR10T2 OR10X1 ADRA1D LPAR6 RRH OR8D4	6.12e-05	677	86	12	PF00001
Domain	K_chnl_volt-dep_ELK	KCNH8 KCNH4	6.27e-05	3	86	2	IPR003950
Domain	Ribonuc_2-5A	ERN1 ERN2	6.27e-05	3	86	2	PF06479
Domain	KEN	ERN1 ERN2	6.27e-05	3	86	2	PS51392
Domain	KEN_dom	ERN1 ERN2	6.27e-05	3	86	2	IPR010513
Domain	PQQ	ERN1 ERN2	6.27e-05	3	86	2	PF01011
Domain	G_PROTEIN_RECEP_F1_1	DRD4 GPR17 FFAR3 GPR42 GPR78 F2RL2 OR10T2 OR10X1 ADRA1D LPAR6 RRH OR8D4	6.85e-05	685	86	12	PS00237
Domain	G_PROTEIN_RECEP_F1_2	DRD4 GPR17 FFAR3 GPR42 GPR78 F2RL2 OR10T2 OR10X1 ADRA1D LPAR6 RRH OR8D4	7.45e-05	691	86	12	PS50262
Domain	GPCR_Rhodpsn	DRD4 GPR17 FFAR3 GPR42 GPR78 F2RL2 OR10T2 OR10X1 ADRA1D LPAR6 RRH OR8D4	7.55e-05	692	86	12	IPR000276
Domain	GPR40-rel_orph	FFAR3 GPR42	1.25e-04	4	86	2	IPR013312
Domain	PUG	ERN1 ERN2	2.08e-04	5	86	2	SM00580
Domain	GPCR_Rhodpsn_7TM	DRD4 GPR17 FFAR3 GPR78 F2RL2 OR10T2 OR10X1 ADRA1D LPAR6 RRH OR8D4	2.47e-04	670	86	11	IPR017452
Domain	PQQ	ERN1 ERN2	3.11e-04	6	86	2	SM00564
Domain	PQQ_beta_propeller_repeat	ERN1 ERN2	3.11e-04	6	86	2	IPR018391
Domain	-	ERN1 ERN2	3.11e-04	6	86	2	2.140.10.10
Domain	Quinoprotein_ADH-like_fam	ERN1 ERN2	3.11e-04	6	86	2	IPR027295
Domain	PUB_domain	ERN1 ERN2	3.11e-04	6	86	2	IPR018997
Domain	PQQ_repeat	ERN1 ERN2	3.11e-04	6	86	2	IPR002372
Domain	DHC_N1	DYNC2H1 DNAH2	5.76e-04	8	86	2	PF08385
Domain	Dynein_heavy_dom-1	DYNC2H1 DNAH2	5.76e-04	8	86	2	IPR013594
Domain	EGF_3	MUC3B DLL4 PRF1 ADGRE1 MUC3A OTOG	7.56e-04	235	86	6	PS50026
Domain	PAS_9	KCNH8 KCNH4	9.21e-04	10	86	2	PF13426
Domain	EGF-like_dom	MUC3B DLL4 PRF1 ADGRE1 MUC3A OTOG	1.02e-03	249	86	6	IPR000742
Domain	EGF_1	MUC3B FN1 DLL4 PRF1 ADGRE1 MUC3A	1.15e-03	255	86	6	PS00022
Domain	EGF-like_CS	MUC3B FN1 DLL4 PRF1 ADGRE1 MUC3A	1.30e-03	261	86	6	IPR013032
Domain	Sushi	APOH CSMD3 CSMD1	1.77e-03	52	86	3	PF00084
Domain	SEA	MUC3B MUC3A	1.84e-03	14	86	2	SM00200
Domain	Dynein_heavy_chain_D4_dom	DYNC2H1 DNAH2	1.84e-03	14	86	2	IPR024317
Domain	K_chnl_volt-dep_EAG/ELK/ERG	KCNH8 KCNH4	1.84e-03	14	86	2	IPR003938
Domain	Dynein_HC_stalk	DYNC2H1 DNAH2	1.84e-03	14	86	2	IPR024743
Domain	Dynein_heavy_dom-2	DYNC2H1 DNAH2	1.84e-03	14	86	2	IPR013602
Domain	DHC_N2	DYNC2H1 DNAH2	1.84e-03	14	86	2	PF08393
Domain	MT	DYNC2H1 DNAH2	1.84e-03	14	86	2	PF12777
Domain	AAA_8	DYNC2H1 DNAH2	1.84e-03	14	86	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DYNC2H1 DNAH2	1.84e-03	14	86	2	IPR011704
Domain	AAA_5	DYNC2H1 DNAH2	1.84e-03	14	86	2	PF07728
Domain	CCP	APOH CSMD3 CSMD1	1.97e-03	54	86	3	SM00032
Domain	DHC_fam	DYNC2H1 DNAH2	2.12e-03	15	86	2	IPR026983
Domain	Dynein_heavy_dom	DYNC2H1 DNAH2	2.12e-03	15	86	2	IPR004273
Domain	Dynein_heavy	DYNC2H1 DNAH2	2.12e-03	15	86	2	PF03028
Domain	SUSHI	APOH CSMD3 CSMD1	2.19e-03	56	86	3	PS50923
Domain	Sushi_SCR_CCP_dom	APOH CSMD3 CSMD1	2.31e-03	57	86	3	IPR000436
Domain	SAM_1	DDHD2 SAMD14 ARAP2	3.81e-03	68	86	3	PF00536
Domain	UDPGT	UGT1A4 UGT1A1	4.16e-03	21	86	2	PF00201
Domain	UDPGT	UGT1A4 UGT1A1	4.16e-03	21	86	2	PS00375
Domain	UDP_glucos_trans	UGT1A4 UGT1A1	4.16e-03	21	86	2	IPR002213
Domain	AAA+_ATPase	ABCC4 DYNC2H1 DNAH2 ABCC11	4.41e-03	144	86	4	IPR003593
Domain	AAA	ABCC4 DYNC2H1 DNAH2 ABCC11	4.41e-03	144	86	4	SM00382
Pathway	REACTOME_CD22_MEDIATED_BCR_REGULATION	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	9.22e-10	61	74	8	M27581
Pathway	REACTOME_FCGR3A_MEDIATED_IL10_SYNTHESIS	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 ADCY8 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	1.50e-09	95	74	9	M29842
Pathway	REACTOME_FCGR_ACTIVATION	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	2.53e-09	69	74	8	M27108
Pathway	REACTOME_SCAVENGING_OF_HEME_FROM_PLASMA	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	2.53e-09	69	74	8	M27150
Pathway	REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	3.19e-09	71	74	8	M1078
Pathway	REACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	3.19e-09	71	74	8	M27203
Pathway	REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	8.38e-09	80	74	8	M6121
Pathway	REACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	1.02e-08	82	74	8	M27110
Pathway	REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	1.50e-08	86	74	8	M601
Pathway	REACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	1.50e-08	86	74	8	M27206
Pathway	REACTOME_FCERI_MEDIATED_MAPK_ACTIVATION	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	1.64e-08	87	74	8	M27205
Pathway	REACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 ADCY8 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	3.17e-08	134	74	9	M29840
Pathway	REACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	4.22e-08	98	74	8	M27152
Pathway	REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 FN1 IGKV1-5 CD44 IGKV1D-39 IGKV1D-16 IGKV1D-12	6.46e-08	194	74	10	M16312
Pathway	REACTOME_COMPLEMENT_CASCADE	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	1.48e-07	115	74	8	M19752
Pathway	REACTOME_PARASITE_INFECTION	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	1.58e-07	116	74	8	M29843
Pathway	REACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	5.38e-07	136	74	8	M27207
Pathway	REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	7.89e-07	143	74	8	M27107
Pathway	REACTOME_POTENTIAL_THERAPEUTICS_FOR_SARS	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	1.38e-06	154	74	8	M39007
Pathway	REACTOME_LEISHMANIA_INFECTION	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 ADCY8 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	2.06e-06	219	74	9	M29836
Pathway	REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	2.43e-06	166	74	8	M608
Pathway	REACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	5.66e-06	186	74	8	M27175
Pathway	REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	6.62e-06	190	74	8	M8240
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	CCL4L1 DRD4 GPR17 FFAR3 GPR42 F2RL2 ADRA1D LPAR6 RRH CCL4	8.88e-06	333	74	10	MM14963
Pathway	REACTOME_HEMOSTASIS	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 ABCC4 FN1 APOH F2RL2 IGKV1-5 CD44 IGKV1D-39 IGKV1D-16 IGKV1D-12 KLKB1	9.84e-06	679	74	14	M8395
Pathway	WP_GPCRS_NONODORANT	DRD4 GPR17 FFAR3 GPR42 F2RL2 ADRA1D LPAR6 RRH ADGRE1	1.00e-05	266	74	9	MM15843
Pathway	REACTOME_GPCR_LIGAND_BINDING	CCL4L1 DRD4 GPR17 FFAR3 GPR42 F2RL2 ADRA1D LPAR6 RRH CCL4 ADGRE1	1.39e-05	430	74	11	MM15160
Pathway	REACTOME_SIGNALING_BY_GPCR	CCL4L1 DRD4 GPR17 FN1 FFAR3 GPR42 F2RL2 ADCY8 ADRA1D LPAR6 RRH CCL4 ADGRE1	2.76e-05	646	74	13	MM14962
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	DRD4 GPR17 FFAR3 GPR42 F2RL2 ADRA1D LPAR6 RRH	6.33e-05	260	74	8	M39397
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	DRD4 GPR17 FFAR3 F2RL2 ADRA1D LPAR6 RRH CCL4	3.26e-04	330	74	8	M18334
Pathway	REACTOME_METABOLISM_OF_PORPHYRINS	UGT1A4 UGT1A1 FECH	3.71e-04	27	74	3	M1088
Pathway	WP_CILIOPATHIES	RPGRIP1 RPGRIP1L DYNC2H1 TTLL5 OCRL TBC1D32	4.05e-04	184	74	6	M39880
Pathway	WP_PREGNANE_X_RECEPTOR_PATHWAY	ABCC4 UGT1A4 UGT1A1	6.17e-04	32	74	3	M39567
Pathway	REACTOME_METABOLISM_OF_PORPHYRINS	UGT1A4 UGT1A1 FECH	6.17e-04	32	74	3	MM14719
Pathway	REACTOME_GPCR_LIGAND_BINDING	DRD4 GPR17 FFAR3 F2RL2 ADRA1D LPAR6 RRH CCL4 ADGRE1	6.84e-04	463	74	9	M507
Pathway	REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS	GPR17 FFAR3 GPR42 F2RL2 ADRA1D LPAR6	8.12e-04	210	74	6	MM15043
Pathway	REACTOME_SIGNALING_BY_GPCR	DRD4 GPR17 FN1 FFAR3 F2RL2 ADCY8 ADRA1D LPAR6 RRH CCL4 ADGRE1	1.03e-03	702	74	11	M746
Pathway	KEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM	UGT1A4 UGT1A1 FECH	1.28e-03	41	74	3	M7399
Pathway	REACTOME_P2Y_RECEPTORS	GPR17 LPAR6	1.45e-03	11	74	2	MM15049
Pathway	REACTOME_P2Y_RECEPTORS	GPR17 LPAR6	1.73e-03	12	74	2	M10960
Pubmed	Variation in the crossover point of kappa immunoglobulin gene V-J recombination: evidence from a cryptic gene.	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-17 IGKV1D-13	9.28e-24	9	100	9	6777049
Pubmed	Characteristics of the immunoglobulin Vkappa genes, pseudogenes, relics and orphons in the mouse genome.	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-13	1.03e-23	20	100	11	10427970
Pubmed	Structure and implied functions of truncated B-cell receptor mRNAs in early embryo and adult mesenchymal stem cells: Cdelta replaces Cmu in mu heavy chain-deficient mice.	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-17 IGKV1D-13	1.04e-19	16	100	9	17124007
Pubmed	Human myeloperoxidase in innate and acquired immunity.	IGKV1-39 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-13 IGKV1D-12	4.42e-19	18	100	9	20399194
Pubmed	Amino acid sequence of the variable region of M149 mouse myeloma light chain: comparison with the nucleotide sequence of K2 and K3 clones.	IGKV1-39 IGKV1-13 IGKV1-9 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-13	4.29e-16	11	100	7	6795447
Pubmed	Multiple related immunoglobulin variable-region genes identified by cloning and sequence analysis.	IGKV1-39 IGKV1-13 IGKV1-9 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-13	4.29e-16	11	100	7	279004
Pubmed	Organization and complete sequence of identical embryonic and plasmacytoma kappa V-region genes.	IGKV1-39 IGKV1-13 IGKV1-9 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-13	4.29e-16	11	100	7	6767723
Pubmed	IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes.	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-17 IGKV1D-13	1.28e-12	77	100	9	15608191
Pubmed	The V kappa genes of the L regions and the repertoire of V kappa gene sequences in the human germ line.	IGKV1-17 IGKV1-12 IGKV1D-43 IGKV1D-17 IGKV1D-13 IGKV1D-12	5.85e-12	17	100	6	8223863
Pubmed	Evolutionary dynamics of the human immunoglobulin kappa locus and the germline repertoire of the Vkappa genes.	IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	8.82e-10	36	100	6	11298326
Pubmed	Organization and evolution of a gene cluster for human immunoglobulin variable regions of the kappa type.	IGKV1-13 IGKV1-12 IGKV1-9	2.30e-07	5	100	3	6086934
Pubmed	Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia.	FFAR3 GPR42	8.18e-06	2	100	2	25637492
Pubmed	Selective tracking of FFAR3-expressing neurons supports receptor coupling to N-type calcium channels in mouse sympathetic neurons.	FFAR3 GPR42	8.18e-06	2	100	2	30478340
Pubmed	The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule.	ERN1 ERN2	8.18e-06	2	100	2	22315414
Pubmed	Intestinal FFA3 mediates obesogenic effects in mice on a Western diet.	FFAR3 GPR42	8.18e-06	2	100	2	35858247
Pubmed	Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms.	FFAR3 GPR42	8.18e-06	2	100	2	22506074
Pubmed	Impaired 2',3'-dideoxy-3'-thiacytidine accumulation in T-lymphoblastoid cells as a mechanism of acquired resistance independent of multidrug resistant protein 4 with a possible role for ATP-binding cassette C11.	ABCC4 ABCC11	8.18e-06	2	100	2	12133003
Pubmed	The effects of propionate and valerate on insulin responsiveness for glucose uptake in 3T3-L1 adipocytes and C2C12 myotubes via G protein-coupled receptor 41.	FFAR3 GPR42	8.18e-06	2	100	2	24748202
Pubmed	The Cognitive Improvement and Alleviation of Brain Hypermetabolism Caused by FFAR3 Ablation in Tg2576 Mice Is Persistent under Diet-Induced Obesity.	FFAR3 GPR42	8.18e-06	2	100	2	36362376
Pubmed	Multiple transcripts of MUC3: evidence for two genes, MUC3A and MUC3B.	MUC3B MUC3A	8.18e-06	2	100	2	10973822
Pubmed	Phage display of a human antibody against Clostridium tetani toxin.	IGKV1-39 IGKV1D-39	8.18e-06	2	100	2	7926831
Pubmed	Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids.	FFAR3 GPR42	8.18e-06	2	100	2	20399779
Pubmed	Male mice that lack the G-protein-coupled receptor GPR41 have low energy expenditure and increased body fat content.	FFAR3 GPR42	8.18e-06	2	100	2	23110765
Pubmed	The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation.	FFAR3 GPR42	8.18e-06	2	100	2	26522986
Pubmed	Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress.	ERN1 ERN2	8.18e-06	2	100	2	11175748
Pubmed	Endoplasmic reticulum stress in the regulation of liver diseases: Involvement of Regulated IRE1α and β-dependent decay and miRNA.	ERN1 ERN2	8.18e-06	2	100	2	27774654
Pubmed	Characterization of two homologs of Ire1p, a kinase/endoribonuclease in yeast, in Arabidopsis thaliana.	ERN1 ERN2	8.18e-06	2	100	2	12020828
Pubmed	Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41.	FFAR3 GPR42	8.18e-06	2	100	2	27664183
Pubmed	A novel putative transporter maps to the osteosclerosis (oc) mutation and is not expressed in the oc mutant mouse.	TCIRG1 SLC22A8	8.18e-06	2	100	2	10087192
Pubmed	G protein coupled receptor 41 regulates fibroblast activation in pulmonary fibrosis via Gαi/o and downstream Smad2/3 and ERK1/2 phosphorylation.	FFAR3 GPR42	8.18e-06	2	100	2	37019194
Pubmed	3-(4-Hydroxy-3-methoxyphenyl) propionic acid contributes to improved hepatic lipid metabolism via GPR41.	FFAR3 GPR42	8.18e-06	2	100	2	38040866
Pubmed	Genetic Inactivation of Free Fatty Acid Receptor 3 Impedes Behavioral Deficits and Pathological Hallmarks in the APPswe Alzheimer's Disease Mouse Model.	FFAR3 GPR42	8.18e-06	2	100	2	35408893
Pubmed	FFAR3 modulates insulin secretion and global gene expression in mouse islets.	FFAR3 GPR42	8.18e-06	2	100	2	26091414
Pubmed	Initiation of transcription of the MUC3A human intestinal mucin from a TATA-less promoter and comparison with the MUC3B amino terminus.	MUC3B MUC3A	8.18e-06	2	100	2	12958310
Pubmed	GPR41 modulates insulin secretion and gene expression in pancreatic β-cells and modifies metabolic homeostasis in fed and fasting states.	FFAR3 GPR42	8.18e-06	2	100	2	27550964
Pubmed	Functional and non-functional joining in immunoglobulin light chain genes of a mouse myeloma.	IGKV1-12 IGKV1D-12	8.18e-06	2	100	2	6776411
Pubmed	Free fatty acid receptor 3 differentially contributes to β-cell compensation under high-fat diet and streptozotocin stress.	FFAR3 GPR42	8.18e-06	2	100	2	32073900
Pubmed	Variable region sequences of autoantibodies from mice with experimental systemic lupus erythematosus.	IGKV1-12 IGKV1D-12	8.18e-06	2	100	2	8325334
Pubmed	Lack of association of CD44-rs353630 and CHI3L2-rs684559 with pancreatic ductal adenocarcinoma survival.	CHI3L2 CD44	8.18e-06	2	100	2	33828170
Pubmed	Cloning and expression of a lymphocyte activation gene (LAG-1).	CCL4L1 CCL4	8.18e-06	2	100	2	2247088
Pubmed	Sequence polymorphisms provide a common consensus sequence for GPR41 and GPR42.	FFAR3 GPR42	8.18e-06	2	100	2	19630535
Pubmed	MUC3 human intestinal mucin. Analysis of gene structure, the carboxyl terminus, and a novel upstream repetitive region.	MUC3B MUC3A	8.18e-06	2	100	2	9334251
Pubmed	Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression.	ERN1 ERN2	8.18e-06	2	100	2	16581782
Pubmed	Molecular cloning of cDNAs derived from a novel human intestinal mucin gene.	MUC3B MUC3A	8.18e-06	2	100	2	2393399
Pubmed	Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease.	MUC3B MUC3A	8.18e-06	2	100	2	11289722
Pubmed	Founder genetic variants of ABCC4 and ABCC11 in the Japanese population are not associated with the development of subacute myelo-optico-neuropathy (SMON).	ABCC4 ABCC11	8.18e-06	2	100	2	34951141
Pubmed	Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41.	FFAR3 GPR42	8.18e-06	2	100	2	14722361
Pubmed	Cloning and characterization of 1116NS19.9 heavy and light chain cDNAs and expression of antibody fragments in Escherichia coli.	IGKV1-12 IGKV1D-12	8.18e-06	2	100	2	8372513
Pubmed	High levels of Notch intracellular cleaved domain are associated with stemness and reduced bevacizumab efficacy in patients with advanced colon cancer.	DLL4 CD44	8.18e-06	2	100	2	31578584
Pubmed	Cell type-specific regulation of ciliary transition zone assembly in vertebrates.	RPGRIP1 RPGRIP1L	8.18e-06	2	100	2	29650680
Pubmed	RNase domains determine the functional difference between IRE1alpha and IRE1beta.	ERN1 ERN2	8.18e-06	2	100	2	18242182
Pubmed	Human GPR42 is a transcribed multisite variant that exhibits copy number polymorphism and is functional when heterologously expressed.	FFAR3 GPR42	8.18e-06	2	100	2	26260360
Pubmed	The MUC3 gene encodes a transmembrane mucin and is alternatively spliced.	MUC3B MUC3A	8.18e-06	2	100	2	10405327
Pubmed	Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1.	ERN1 ERN2	8.18e-06	2	100	2	16950141
Pubmed	The human plasma proteome: a nonredundant list developed by combination of four separate sources.	FN1 APOH TG GHR CCL4 KLKB1	8.58e-06	165	100	6	14718574
Pubmed	cIAPs control RIPK1 kinase activity-dependent and -independent cell death and tissue inflammation.	CCL4L1 CCL4 ADGRE1	1.26e-05	16	100	3	37789765
Pubmed	IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response.	ERN1 ERN2	2.45e-05	3	100	2	11850408
Pubmed	Identification of two new members of the CSMD gene family.	CSMD3 CSMD1	2.45e-05	3	100	2	12906867
Pubmed	Novel interaction of apolipoprotein(a) with beta-2 glycoprotein I mediated by the kringle IV domain.	FN1 APOH	2.45e-05	3	100	2	9269765
Pubmed	Immunoglobulin genes of the kappa light chain type from two human lymphoid cell lines are closely related.	IGKV1-39 IGKV1D-39	2.45e-05	3	100	2	6091049
Pubmed	The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.	FFAR3 GPR42	2.45e-05	3	100	2	12496283
Pubmed	Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in mice.	FFAR3 GPR42	2.45e-05	3	100	2	23665276
Pubmed	A Novel Resolution of Diabetes: C-C Chemokine Motif Ligand 4 Is a Common Target in Different Types of Diabetes by Protecting Pancreatic Islet Cell and Modulating Inflammation.	CCL4L1 CCL4	2.45e-05	3	100	2	33968046
Pubmed	Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer.	FFAR3 GPR42	2.45e-05	3	100	2	34210970
Pubmed	Expression of mucin 3 and mucin 5AC in arthritic synovial tissue.	MUC3B MUC3A	2.45e-05	3	100	2	18163520
Pubmed	Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization.	ERN1 ERN2	2.45e-05	3	100	2	29511123
Pubmed	Critical role of CCL4 in eosinophil recruitment into the airway.	CCL4L1 CCL4	2.45e-05	3	100	2	30854716
Pubmed	Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client.	ERN1 GPR78	2.45e-05	3	100	2	28416388
Pubmed	Multiple products derived from two CCL4 loci: high incidence of a new polymorphism in HIV+ patients.	CCL4L1 CCL4	2.45e-05	3	100	2	15843566
Pubmed	Serum complement C4b, fibronectin, and prolidase are associated with the pathological changes of pulmonary tuberculosis.	FN1 PEPD	2.45e-05	3	100	2	24484408
Pubmed	Dietary short-chain fatty acid intake improves the hepatic metabolic condition via FFAR3.	FFAR3 GPR42	2.45e-05	3	100	2	31719611
Pubmed	Identification, cloning, and characterization of an immune activation gene.	CCL4L1 CCL4	2.45e-05	3	100	2	2462251
Pubmed	Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin.	MUC3B MUC3A	2.45e-05	3	100	2	10512748
Pubmed	The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response.	ERN1 ERN2	2.45e-05	3	100	2	16973740
Pubmed	An ATF/CREB-binding site is essential for cell-specific and inducible transcription of the murine MIP-1 beta cytokine gene.	CCL4L1 CCL4	2.45e-05	3	100	2	7835696
Pubmed	Isolation and characterization of a cDNA encoding a putative cytokine which is induced by stimulation via the CD2 structure on human T lymphocytes.	CCL4L1 CCL4	2.45e-05	3	100	2	2568930
Pubmed	The ciliopathy-associated protein homologs RPGRIP1 and RPGRIP1L are linked to cilium integrity through interaction with Nek4 serine/threonine kinase.	RPGRIP1 RPGRIP1L	2.45e-05	3	100	2	21685204
Pubmed	Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes.	FFAR3 GPR42	2.45e-05	3	100	2	25581519
Pubmed	Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8+ T Cells.	FFAR3 GPR42	2.45e-05	3	100	2	31272808
Pubmed	Co-localization of insulin-like growth factor binding protein 3 and fibronectin in human articular cartilage.	FN1 CD44	2.45e-05	3	100	2	12127836
Pubmed	Bone marrow-derived monocyte lineage cells recruited by MIP-1β promote physiological revascularization in mouse model of oxygen-induced retinopathy.	CCL4L1 CCL4	2.45e-05	3	100	2	21912378
Pubmed	GPR41 and GPR43 regulate CD8+ T cell priming during herpes simplex virus type 1 infection.	FFAR3 GPR42	2.45e-05	3	100	2	38524121
Pubmed	Synoviolin promotes IRE1 ubiquitination and degradation in synovial fibroblasts from mice with collagen-induced arthritis.	ERN1 ERN2	2.45e-05	3	100	2	18369366
Pubmed	Loss of RPGR glutamylation underlies the pathogenic mechanism of retinal dystrophy caused by TTLL5 mutations.	RPGRIP1 TTLL5	2.45e-05	3	100	2	27162334
Pubmed	Species difference in the inhibitory effect of nonsteroidal anti-inflammatory drugs on the uptake of methotrexate by human kidney slices.	ABCC4 SLC22A8	2.45e-05	3	100	2	17578901
Pubmed	Short-chain fatty acid receptor GPR41-mediated activation of sympathetic neurons involves synapsin 2b phosphorylation.	FFAR3 GPR42	2.45e-05	3	100	2	22673524
Pubmed	Inhibition of macrophage inflammatory protein-1β improves endothelial progenitor cell function and ischemia-induced angiogenesis in diabetes.	CCL4L1 CCL4	2.45e-05	3	100	2	29987448
Pubmed	The gene encoding the Act-2 cytokine. Genomic structure, HTLV-I/Tax responsiveness of 5' upstream sequences, and chromosomal localization.	CCL4L1 CCL4	2.45e-05	3	100	2	1894635
Pubmed	Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1.	ERN1 ERN2	2.45e-05	3	100	2	10650002
Pubmed	High-resolution solution structure of the beta chemokine hMIP-1 beta by multidimensional NMR.	CCL4L1 CCL4	2.45e-05	3	100	2	8134838
Pubmed	Knockdown of IRE1ɑ suppresses metastatic potential of colon cancer cells through inhibiting FN1-Src/FAK-GTPases signaling.	FN1 ERN1	2.45e-05	3	100	2	31326465
Pubmed	Distribution and functional properties of human KCNH8 (Elk1) potassium channels.	KCNH8 KCNH4	2.45e-05	3	100	2	12890647
Pubmed	Acetate and propionate short chain fatty acids stimulate adipogenesis via GPCR43.	FFAR3 GPR42	2.45e-05	3	100	2	16123168
Pubmed	GPR41 gene expression is mediated by internal ribosome entry site (IRES)-dependent translation of bicistronic mRNA encoding GPR40 and GPR41 proteins.	FFAR3 GPR42	2.45e-05	3	100	2	22493486
Pubmed	Cloning of mammalian Ire1 reveals diversity in the ER stress responses.	ERN1 ERN2	2.45e-05	3	100	2	9755171
Pubmed	The human MIP-1beta chemokine is encoded by two paralogous genes, ACT-2 and LAG-1.	CCL4L1 CCL4	2.45e-05	3	100	2	11685466
Pubmed	Involvement of CD4+ and CD8+ T-lymphocytes in the modulation of nociceptive processing evoked by CCL4 in mice.	CCL4L1 CCL4	2.45e-05	3	100	2	34999112
Pubmed	Extracellular ionic locks determine variation in constitutive activity and ligand potency between species orthologs of the free fatty acid receptors FFA2 and FFA3.	FFAR3 GPR42	2.45e-05	3	100	2	23066016
Pubmed	CCL4 protects from type 1 diabetes by altering islet beta-cell-targeted inflammatory responses.	CCL4L1 CCL4	2.45e-05	3	100	2	17327452
Pubmed	Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2.	FFAR3 GPR42	2.45e-05	3	100	2	22190648
Cytoband	2p12	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	9.29e-21	117	101	14	2p12
Cytoband	Ensembl 112 genes in cytogenetic band chr2p11	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	5.00e-17	213	101	14	chr2p11
Cytoband	19q13.1	FFAR3 GPR42 CATSPERG	2.49e-04	55	101	3	19q13.1
Cytoband	6q22.31	TBC1D32 SERINC1	1.62e-03	27	101	2	6q22.31
Cytoband	8q24	ADCY8 TG	1.75e-03	28	101	2	8q24
Cytoband	17q24.2	ERN1 APOH	2.00e-03	30	101	2	17q24.2
Cytoband	2q37	UGT1A4 UGT1A1	2.14e-03	31	101	2	2q37
Cytoband	7q22	MUC3B MUC3A	3.20e-03	38	101	2	7q22
Cytoband	Xq25	OCRL IGSF1	3.72e-03	41	101	2	Xq25
Cytoband	1q23.1	OR10T2 OR10X1	4.66e-03	46	101	2	1q23.1
GeneFamily	Immunoglobulin kappa locus at 2p11.2	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	3.90e-19	83	77	14	351
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RPGRIP1 RPGRIP1L PRF1	4.79e-04	36	77	3	823
GeneFamily	ATP binding cassette subfamily C	ABCC4 ABCC11	1.35e-03	13	77	2	807
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	APOH CSMD3 CSMD1	1.84e-03	57	77	3	1179
GeneFamily	CD molecules\|Mucins	MUC3B MUC3A	3.57e-03	21	77	2	648
GeneFamily	G protein-coupled receptors, Class A orphans	GPR17 GPR42 GPR78	4.49e-03	78	77	3	262
Coexpression	RASHI_RESPONSE_TO_IONIZING_RADIATION_6	IGKV1-39 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-13 IGKV1D-12	1.55e-09	132	97	9	MM996
CoexpressionAtlas	AravindRamakr_StemCell-HD_top-relative-expression-ranked_1000_k-means-cluster#3	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-39	8.82e-06	183	85	7	Arv_SC-HD_1000_K3
CoexpressionAtlas	AravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500_k-means-cluster#2	IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-9 IGKV1-5 IGKV1D-39	4.95e-05	163	85	6	Arv_SC-hpx_blastocyst_500_K2
CoexpressionAtlas	PP_HSC_top-relative-expression-ranked_2500_k-means-cluster#3	IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-9 IGKV1-6 CPAMD8 IGKV1D-39 ADGRE1	6.43e-05	339	85	8	PP_HSC_2500_K3
CoexpressionAtlas	AravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_500_k-means-cluster#3	IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-9 IGKV1-5 IGKV1D-39	7.34e-05	175	85	6	Arv_SC-H9hpx_500_K3
CoexpressionAtlas	AravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000_k-means-cluster#5	IGKV1-39 IGKV1-16 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-39	9.39e-05	183	85	6	Arv_SC_fibroblast_1000_K5
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 KCNH8 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	3.79e-19	197	99	15	9fe1b757f76c2d43d39aa9ac500eaba98723985c
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	9.80e-18	190	99	14	79ee6d10dfbb775da149a1104da5823cf63bbb46
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	9.80e-18	190	99	14	18762ce78ed0b206ade19e1c8ff76a2647489f68
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	1.32e-17	194	99	14	6ef4aeb8d8e35e4df58ff2a8256caa2113291de9
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	1.42e-17	195	99	14	f3f7f1a77a1edd2b50a8211c76fe289738eb04cf
ToppCell	5'-Adult-LargeIntestine-Hematopoietic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 CCL4L1 IGKV1-5 PRF1 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13	4.33e-16	191	99	13	d1d30279ed4612b4f62c225d9eabf0b8a7a09d11
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	4.96e-16	193	99	13	34f6c13884fdf7f8a87f942fcb36a58cfac3f65d
ToppCell	Biopsy_IPF-Immune-Plasma_cells\|Biopsy_IPF / Sample group, Lineage and Cell type	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13	6.07e-16	196	99	13	a1b6a8000b86efcb07843998aa3a49bb1f54bcda
ToppCell	IPF-Lymphoid-B_Plasma\|IPF / Disease state, Lineage and Cell class	IGKV1-39 IGKV1-17 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	6.04e-15	176	99	12	e4f33f6cd140dd4fa3002bcd65ac8005d27865d1
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	7.41e-15	179	99	12	494febe77c6d4e6a2c6f0928bbf4c84b0301f188
ToppCell	COPD-Lymphoid-B_Plasma\|World / Disease state, Lineage and Cell class	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-5 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13	2.10e-13	175	99	11	d73ee324479172501481b54967a0f3bd870fcf3a
ToppCell	Control-Lymphoid_P-Plasmablast\|Control / Disease group, lineage and cell class	IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	2.24e-13	176	99	11	4b4416f342b732d2cc60133838728880326257d8
ToppCell	Control-Lymphoid_P\|Control / Disease group, lineage and cell class	IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	2.24e-13	176	99	11	d895a6b295cd649273ff80ad7785a3e0ae4c728a
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	2.70e-13	179	99	11	837ed81f18257f444eaeadc4fac89deedd4e3061
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	2.70e-13	179	99	11	b6ee4f41d8fb5f047b7bdd8489dda0a89fc6d43f
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-43 IGKV1D-17 IGKV1D-13	3.05e-13	181	99	11	e47664a264a2c37390d1668ce04eef2e0172f4cb
ToppCell	healthy_donor-Lymphocytic-Plasma_cell-IgA_Plasmablast\|healthy_donor / Disease condition, Lineage, Cell class and subclass	IGKV1-17 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	4.11e-13	186	99	11	e2c050ba02e1f84f0b7258dc92e7ff6ab349ff67
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-13	4.90e-13	189	99	11	5a42be62552d912d0abf68f00d75ac80bbd69f2c
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_plasma\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-13 IGKV1D-12	6.16e-13	193	99	11	282b47dae6043eabb1e13d41d91c07b5ec21cd65
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12	7.30e-13	196	99	11	fec21383435779bf4c632decd3d29c6ca7baebfb
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	7.91e-12	177	99	10	4c434a7b7cc54cf4dac996bbc3f5124d9ef9a9cd
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	7.91e-12	177	99	10	d746122bf8d208c3aa4d156e8c12d0a0e555c6e5
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	7.91e-12	177	99	10	fc40918825b7e1eb6861df59dfca944778a64b98
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-39 IGKV1D-17 IGKV1D-13	1.23e-11	185	99	10	0fff2608f507e019ebb69c27e58fd5be3b049bef
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-39 IGKV1D-17 IGKV1D-13	1.23e-11	185	99	10	79edc1eeb7b5b9123961ac3ecf398ee68d9dddb9
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-39 IGKV1-17 IGKV1-12 TXNDC11 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12	1.23e-11	185	99	10	08bc817908076734d66f2805cb954141f2cc5a18
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-39 IGKV1-17 IGKV1-12 TXNDC11 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12	1.23e-11	185	99	10	1704a12153a9b107bf03ecccd1a036cf61334d7a
ToppCell	healthy_donor-Lymphocytic-Plasma_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	IGKV1-17 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13 IGKV1D-12	1.44e-11	188	99	10	bd53b0371154cff680226897b61c9809a239d1b6
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TDRD15 IGKV1-12 IGKV1-9 ERN1 BRCA2 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13	1.68e-11	191	99	10	da4062a0f6d0af6d330acf11da216c64b0fa7c73
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-17 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-17 IGKV1D-12	1.97e-11	194	99	10	a4a70369541876e1192df8828b63e3d1746ae3d9
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_plasma\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12	2.17e-11	196	99	10	c38e7f533c619afe008de0e99042f7180c2da918
ToppCell	normal_Lung-B_lymphocytes-MALT_B_cells\|normal_Lung / Location, Cell class and cell subclass	IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-13	9.03e-11	159	99	9	fbd0131b66f4267f7b0d6c3ad874ad097b859074
ToppCell	10x5'-GI_large-bowel\|World / Manually curated celltypes from each tissue	IGKV1-39 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-16	1.48e-10	168	99	9	1290c909655bc37f6b8bf216d18127a21b99e9c0
ToppCell	BAL-Mild-Lymphocyte-B\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 KCNH8 IGKV1-5 IGKV1D-39 IGKV1D-12	1.56e-10	169	99	9	307571e57c3bfdf15f0fe1a8b36585e8e4f8a207
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell-B_activate-7\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 KCNH8 IGKV1-5 IGKV1D-39 IGKV1D-12	1.64e-10	170	99	9	ee2ee67d90ae4596de8ccd620e37c82cf51651d4
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 KCNH8 IGKV1-5 IGKV1D-39 IGKV1D-12	1.64e-10	170	99	9	d7ca0c6ce5d2b7de99346f87e07aa7fe728fa08a
ToppCell	BAL-Mild-Lymphocyte-B-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 KCNH8 IGKV1-5 IGKV1D-39 IGKV1D-12	1.64e-10	170	99	9	52787f6d529c285d9f0c04cc022710ead5b89b3f
ToppCell	metastatic_Brain-B_lymphocytes-Plasma_cells\|metastatic_Brain / Location, Cell class and cell subclass	IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-17	1.64e-10	170	99	9	53634da9e9c72f6400639954c286c6e38ea5a188
ToppCell	Control-Lymphoid-B_Plasma\|Control / Disease state, Lineage and Cell class	IGKV1-39 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-16 IGKV1D-13	1.82e-10	172	99	9	61e33836b8cb0f347f3e699eb587a37073b6fa4c
ToppCell	metastatic_Brain-B_lymphocytes-MALT_B_cells\|metastatic_Brain / Location, Cell class and cell subclass	IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-13 IGKV1D-12	2.23e-10	176	99	9	50e207403d48ce1b55a78897adb5519a2430a626
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 ERN1 TXNDC11 IGKV1-5 IGKV1D-39	2.35e-10	177	99	9	c2b0fb5921eea24d248d6e6ccb57c29b0832602c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 ERN1 TXNDC11 IGKV1-5 IGKV1D-39	2.35e-10	177	99	9	111fb0707ff37ca631d85bb5a09e067ffe568eb8
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_B_plasma-Plasma_cells\|lymph-node_spleen / Manually curated celltypes from each tissue	IGKV1-17 IGKV1-13 IGKV1-9 TXNDC11 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12	3.16e-10	183	99	9	a6866951866373a1029e04818f4a4a31278c409d
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-17	3.16e-10	183	99	9	cf5c98f451a568308c52da5c926543dd4836c6b2
ToppCell	10x5'-Liver-Lymphocytic_B_plasma-Plasma_cells\|Liver / Manually curated celltypes from each tissue	IGKV1-39 IGKV1-17 IGKV1-13 IGKV1-12 IGKV1-9 TXNDC11 IGKV1D-39 IGKV1D-13 IGKV1D-12	3.32e-10	184	99	9	6f70d8f8ab8362d51f8a58735d42223e06566397
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-17 IGKV1D-13 IGKV1D-12	5.54e-10	195	99	9	df009b18898c10686f75cf72b4ec0eff18f5bb50
ToppCell	COVID_vent-Lymphocytic-Plasma_cell-IgM_Plasmablast\|COVID_vent / Disease condition, Lineage, Cell class and subclass	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 TXNDC11 IGKV1-5 IGKV1D-39 IGKV1D-17	5.80e-10	196	99	9	026a06d8d2089806823e6f6453d3ede84ae93bc6
ToppCell	Tracheal-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-6 IGKV1D-39 IGKV1D-17 IGKV1D-13 IGKV1D-12	6.07e-10	197	99	9	2662138671262b30508c5759038bcdcfe6551696
ToppCell	10x5'-blood-Lymphocytic_B_plasma-Plasma_cells\|blood / Manually curated celltypes from each tissue	IGKV1-16 IGKV1-13 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-43 IGKV1D-13	1.43e-09	147	99	8	58089378fac1743ce99dc4f1bd7b5253a927f050
ToppCell	10x5'-blood-Lymphocytic_B_plasma\|blood / Manually curated celltypes from each tissue	IGKV1-16 IGKV1-13 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-43 IGKV1D-13	1.68e-09	150	99	8	6bab0a8bf78ed7de9e1b67ede7496488f80f4863
ToppCell	tumor_Lymph_Node_/_Brain-B_lymphocytes-MALT_B_cells\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-39	2.66e-09	159	99	8	204e5a675f4684c9570c24c8d34bbf632fd8164a
ToppCell	368C-Lymphocytic-Plasma_cell-\|368C / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-13 IGKV1D-12	3.08e-09	162	99	8	c21a54310b239d999bbc9d8fb5e8fda16e0bc336
ToppCell	368C-Lymphocytic-Plasma_cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-13 IGKV1D-12	3.08e-09	162	99	8	f945688815229c8386cbcbf46deee7df316fa8d3
ToppCell	367C-Lymphocytic-Plasma_cell-\|367C / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-12 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-12	3.91e-09	167	99	8	f2185eb72f0137136f6d71af2a70168fded6c940
ToppCell	367C-Lymphocytic-Plasma_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-12 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-43 IGKV1D-39 IGKV1D-12	3.91e-09	167	99	8	5e768cf24699893e05d1bcb1c92dba2336943a64
ToppCell	10x5'-bone_marrow-Lymphocytic_B_plasma-Plasma_cells\|bone_marrow / Manually curated celltypes from each tissue	IGKV1-39 IGKV1-13 IGKV1-6 DLL4 TXNDC11 IGKV1-5 IGKV1D-39 IGKV1D-13	5.16e-09	173	99	8	300904fd35536a69be81d76fe33fe16544523ceb
ToppCell	10x5'-bone_marrow-Lymphocytic_B_plasma\|bone_marrow / Manually curated celltypes from each tissue	IGKV1-39 IGKV1-13 IGKV1-6 DLL4 TXNDC11 IGKV1-5 IGKV1D-39 IGKV1D-13	5.40e-09	174	99	8	b1931028cf80af5eff6da15d7f0196205f17926f
ToppCell	(2)_Plasma_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-39 IGKV1D-16	6.18e-09	177	99	8	ed3c936bb69f9bc7291b4f6cde1d204078117c48
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-43 IGKV1D-17	7.05e-09	180	99	8	cea079bc02e08c46600eed05ab9924ec90e1e3d3
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-39 IGKV1-12 TXNDC11 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12	7.05e-09	180	99	8	e3877f6ef5f54ff689058b4c996ab1851822f871
ToppCell	BAL-Mild-Lymphocyte-B\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 KCNH8 IGKV1-5 IGKV1D-39	7.36e-09	181	99	8	700adfb41e4e377530f0dd31be89e12f109f3469
ToppCell	Mild-Lymphoid-B\|Mild / Condition, Lineage, Cell class and cell subclass	IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 KCNH8 IGKV1-5 IGKV1D-39	8.02e-09	183	99	8	9b64d2d143525e6f48a191facfd101462ff36324
ToppCell	Mild-Lymphoid-B-\|Mild / Condition, Lineage, Cell class and cell subclass	IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 KCNH8 IGKV1-5 IGKV1D-39	8.02e-09	183	99	8	b5740f05a4dcdbbf24f7bf7a3f57ac01a5e75f60
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 KCNH8 IGKV1-5 IGKV1D-39	8.37e-09	184	99	8	3f8a359e40bebe58545f708682e5e5d1b70cf5cb
ToppCell	BAL-Mild-Lymphocyte-B-B_cell-B_cell-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 KCNH8 IGKV1-5 IGKV1D-39	8.37e-09	184	99	8	64bede8db709fd32f40c03265b96f0b12155bb8a
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-16	8.37e-09	184	99	8	15f2c10101ccc8ed059520fc082ee42593dff269
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-16	8.37e-09	184	99	8	a90a58d9e319afa1cd572e4c2f516fadc42f56e5
ToppCell	BAL-Mild-Lymphocyte-B-B_cell\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 KCNH8 IGKV1-5 IGKV1D-39	8.73e-09	185	99	8	609080adb2cfb105bb7b8efb617553833299f371
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-39	8.73e-09	185	99	8	6ec009e48e50471c28e914c402f500e56a88f8f2
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-9 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-39	8.73e-09	185	99	8	f49ad6401b2abd089e30eba245b11b5031ea2318
ToppCell	IPF-Lymphoid-B_Plasma\|Lymphoid / Disease state, Lineage and Cell class	IGKV1-39 IGKV1-17 IGKV1-13 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-17 IGKV1D-12	9.11e-09	186	99	8	f9c21daf905d0bb0e0e769ca4bb069ea4b1ba25b
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgG_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 ERN1 IGKV1-5 IGKV1D-17 IGKV1D-13	1.27e-08	194	99	8	f083777353e76a2d9c39f8b6cb1a689b68b81c56
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-5 IGKV1D-39 IGKV1D-16	1.32e-08	195	99	8	2d18f08f33f3b261c77b8adf87d1a184cc6d7400
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-13	1.32e-08	195	99	8	13f4ee21568fd747608412d33559d10561dbb3c8
ToppCell	Biopsy_Other_PF-Immune-Plasma_cells\|Biopsy_Other_PF / Sample group, Lineage and Cell type	IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-6 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-13	1.32e-08	195	99	8	d0305c6a68c9e361507b04db94f86873085d49b3
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell-IgG_Plasmablast\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-9 TXNDC11 IGKV1-5 IGKV1D-39 IGKV1D-13	1.43e-08	197	99	8	b754fad4f3caae6de95df901fd96ea8697fe41b1
ToppCell	390C-Lymphocytic-Plasma_cell-\|390C / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-43 IGKV1D-16	6.00e-08	156	99	7	4f92ca30755430db44402afc603d1ecd8bfc3617
ToppCell	390C-Lymphocytic-Plasma_cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-43 IGKV1D-16	6.00e-08	156	99	7	0de2fc695bd5f8d4633c514f71ea941c88137bac
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-9 IGKV1-6 KCNH8 IGKV1-5 IGKV1D-43 IGKV1D-13 IGKV1D-12	7.77e-08	162	99	7	b46158e260bd2f35702cec73e3b035e8e9ec4469
ToppCell	390C-Lymphocytic-Plasma_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-12 IGKV1-9 IGKV1-6 DLL4 IGKV1D-43 IGKV1D-16	9.18e-08	166	99	7	4ba3711a02d3695b27f7cefd7c60e3be009f5bef
ToppCell	390C-Lymphocytic-Plasma_cell-\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	IGKV1-39 IGKV1-12 IGKV1-9 IGKV1-6 DLL4 IGKV1D-43 IGKV1D-16	9.18e-08	166	99	7	35f6ae2664935dda0d883b32a050ced843204f2d
ToppCell	Plasma_cells\|World / lung cells shred on cell class, cell subclass, sample id	IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-39	1.22e-07	173	99	7	52a387e2a4694af61a9223a4c2ecf4e6f762c064
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgG_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGKV1-39 IGKV1-12 ERN1 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-12	1.32e-07	175	99	7	c3d3f11602379aaba65842a98835299e54fccd84
ToppCell	IPF-Lymphoid-B_Plasma\|World / Disease state, Lineage and Cell class	IGKV1-39 IGKV1-13 IGKV1-12 IGKV1-5 IGKV1D-43 IGKV1D-17 IGKV1D-12	1.37e-07	176	99	7	cc0cab6487df6867b529596ec94f55d31aa6ca36
ToppCell	VE-plasma\|VE / Condition, Cell_class and T cell subcluster	IGKV1-39 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-13 IGKV1D-12	1.42e-07	177	99	7	0c1cc0834de55717cb4f69d020339060ce2c9a03
ToppCell	COPD-Lymphoid-B_Plasma\|COPD / Disease state, Lineage and Cell class	IGKV1-39 IGKV1-17 IGKV1-13 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-17	1.42e-07	177	99	7	1b872d3b1e0fca138362098590a634d748dfca60
ToppCell	VE-plasma-\|VE / Condition, Cell_class and T cell subcluster	IGKV1-39 IGKV1-16 IGKV1-13 IGKV1-12 IGKV1-6 IGKV1D-13 IGKV1D-12	1.42e-07	177	99	7	3a3c94cf30012e2aa266bc4d7fe772e45fa90f6d
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGKV1-39 IGKV1-12 IGKV1-9 KCNH8 IGKV1-5 IGKV1D-39 IGKV1D-13	1.48e-07	178	99	7	107dae8b00c4257697a63700e72bb434cdb8406f
ToppCell	normal_Lymph_Node-B_lymphocytes-Plasma_cells\|normal_Lymph_Node / Location, Cell class and cell subclass	IGKV1-17 IGKV1-12 IGKV1-6 TXNDC11 IGKV1-5 IGKV1D-39 IGKV1D-12	1.65e-07	181	99	7	949ac3b60e7fb5968da4c4e872965fb4e10f4a35
ToppCell	10x5'-Lung-Lymphocytic_B\|Lung / Manually curated celltypes from each tissue	IGKV1-39 IGKV1-16 IGKV1-12 KCNH8 IGKV1-5 IGKV1D-39 IGKV1D-12	1.72e-07	182	99	7	310f94437d197eaaaf6e30e68063b33e94befe77
ToppCell	cellseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	IGKV1-39 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-13 IGKV1D-12	1.78e-07	183	99	7	5ab4aa0304b832f98fff89b6c24ad5b7dd014c11
ToppCell	10x5'-Liver-Lymphocytic_B_plasma\|Liver / Manually curated celltypes from each tissue	IGKV1-39 IGKV1-17 IGKV1-13 IGKV1-9 TXNDC11 IGKV1D-39 IGKV1D-13	1.99e-07	186	99	7	a2c7430781f432c9c90ac4d620f4518ff767a223
ToppCell	Mild_COVID-19-B_cell-B_cell\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-6 IGKV1-5 IGKV1D-39	1.99e-07	186	99	7	855a5a00ba2aa1b5c63b8db56d026ddecc546050
ToppCell	COVID-19-Lymphoid-Plasma,_B_cells\|COVID-19 / Condition, Lineage and Cell class	IGKV1-39 IGKV1-17 IGKV1-16 IGKV1-9 IGKV1-5 IGKV1D-39 IGKV1D-17	2.56e-07	193	99	7	bffd97a73365e1dd23ff3b0320b4860f04ec091a
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-B-B_plasma\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-17 IGKV1-12 IGKV1-5 IGKV1D-39 IGKV1D-16 IGKV1D-13	2.84e-07	196	99	7	b3d5540fe8ab9a9cbb9ab5350f5cb0e1aae93584
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-B\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-16 IGKV1-12 KCNH8 IGKV1-5 IGKV1D-39 IGKV1D-13	2.94e-07	197	99	7	88b29d205237f07a9a26cc15a1cf4ed4816a4c4b
ToppCell	Biopsy_Control_(H.)-Immune-Plasma_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	IGKV1-39 IGKV1-12 TXNDC11 IGKV1D-39 IGKV1D-17 IGKV1D-16 IGKV1D-13	2.94e-07	197	99	7	275f38ed7e477000e864cecf9b7d49ae134c3b6a
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	IGKV1-39 IGKV1-16 IGKV1-12 IGKV1-9 TXNDC11 IGKV1D-39 IGKV1D-13	2.94e-07	197	99	7	1e63879633f20646e44873ae6b662f6faf4806fd
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-B-B_cell-B_mature\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	IGKV1-39 IGKV1-17 IGKV1-12 KCNH8 IGKV1-5 IGKV1D-43 IGKV1D-39	3.04e-07	198	99	7	d51ee880acc5804cd918105fac846a1528333d6c
ToppCell	LPS_only-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils\|LPS_only / Treatment groups by lineage, cell group, cell type	MGAM TCIRG1 CHI3L2 PGD CD44 ADGRE1 ARAP2	3.25e-07	200	99	7	3504aeba7b30cac9c428ba3871c072e2202752b4
Drug	tectochrysin	MGAM TG UGT1A4 UGT1A1	1.01e-06	20	89	4	CID005281954
Drug	cidofovir	PEPD TG SLC22A8 CD44 CABIN1	4.42e-06	62	89	5	CID000060613
Drug	fenoldopam	DRD4 FN1 ADCY8 TG ADRA1D	8.07e-06	70	89	5	CID000003340
Drug	nonanoyl-N-methylglucamide	UGT1A4 UGT1A1 CD44	1.24e-05	12	89	3	CID000160090
Drug	deamelin-S	MGAM APOH	1.51e-05	2	89	2	CID000071793
Drug	propranolol glucuronide	UGT1A4 UGT1A1 PLP1	2.04e-05	14	89	3	CID000119515
Disease	plasma renin activity measurement	TXNDC11 GHR KLKB1	2.51e-06	9	93	3	EFO_0006828
Disease	bitter alcoholic beverage consumption measurement	MGAM DNAH2 PEPD LRPPRC ADRA1D CSMD1	4.14e-06	133	93	6	EFO_0010092
Disease	COMM domain-containing protein 1 measurement	IGKV1-17 IGKV1-16	9.83e-06	2	93	2	EFO_0802424
Disease	level of nuclear factor NF-kappa-B p105 subunit in blood serum	IGKV1-17 IGKV1-16	9.83e-06	2	93	2	OBA_2040323
Disease	lumbar disc degeneration	HIVEP1 DYNC2H1 CSMD1	9.38e-05	28	93	3	EFO_0004994
Disease	matrix extracellular phosphoglycoprotein measurement	APOH KLKB1	9.77e-05	5	93	2	EFO_0020557
Disease	interleukin-13 receptor subunit alpha-1 measurement	APOH KLKB1	9.77e-05	5	93	2	EFO_0020493
Disease	Strabismus	RPGRIP1 ABCC11 CSMD1	1.04e-04	29	93	3	HP_0000486
Disease	VACTERL association (implicated_via_orthology)	DYNC2H1 TBC1D32	1.46e-04	6	93	2	DOID:14679 (implicated_via_orthology)
Disease	Cerebellar Diseases	RPGRIP1L ZEB2	2.04e-04	7	93	2	C0007760
Disease	Meckel syndrome (implicated_via_orthology)	RPGRIP1L TBC1D32	2.72e-04	8	93	2	DOID:0050778 (implicated_via_orthology)
Disease	X-11442 measurement	UGT1A4 UGT1A1	3.49e-04	9	93	2	EFO_0021236
Disease	X-11441 measurement	UGT1A4 UGT1A1	3.49e-04	9	93	2	EFO_0021235
Disease	circulating cell free DNA measurement	UGT1A4 UGT1A1	3.49e-04	9	93	2	EFO_0004739
Disease	bilirubin measurement, response to xenobiotic stimulus	UGT1A4 UGT1A1	3.49e-04	9	93	2	EFO_0004570, GO_0009410
Disease	postburn hypertrophic scarring severity measurement	CSMD1 ARAP2	4.35e-04	10	93	2	EFO_0007747
Disease	bilirubin measurement, response to tenofovir	UGT1A4 UGT1A1	4.35e-04	10	93	2	EFO_0004570, EFO_0009279
Disease	UDP-glucuronosyltransferase 1-6 measurement	UGT1A4 UGT1A1	4.35e-04	10	93	2	EFO_0802185
Disease	membranoproliferative glomerulonephritis (biomarker_via_orthology)	FN1 PRF1	4.35e-04	10	93	2	DOID:2920 (biomarker_via_orthology)
Disease	histidine betaine (hercynine) measurement	UGT1A4 UGT1A1	5.31e-04	11	93	2	EFO_0800972
Disease	X-21796 measurement	UGT1A4 UGT1A1	5.31e-04	11	93	2	EFO_0800825
Disease	insomnia, bilirubin measurement	UGT1A4 UGT1A1	5.31e-04	11	93	2	EFO_0004570, EFO_0004698
Disease	aldosterone measurement	UGT1A4 UGT1A1	5.31e-04	11	93	2	EFO_0010219
Disease	biliverdin measurement	UGT1A4 UGT1A1	6.35e-04	12	93	2	EFO_0021033
Disease	Congenital Hypothyroidism	TG IGSF1	7.49e-04	13	93	2	C0010308
Disease	Meckel-Gruber syndrome	RPGRIP1 RPGRIP1L	1.00e-03	15	93	2	C0265215
Disease	ureidopropionic acid measurement	RPGRIP1L OTOG	1.15e-03	16	93	2	EFO_0010542
Disease	cyclic adenosine monophosphate measurement	ABCC4 ARAP2	1.30e-03	17	93	2	EFO_0010473
Disease	low density lipoprotein cholesterol measurement, body fat percentage	UGT1A4 UGT1A1	1.30e-03	17	93	2	EFO_0004611, EFO_0007800
Disease	cholesterol to total lipids in chylomicrons and extremely large VLDL percentage	TDRD15 APOH	1.30e-03	17	93	2	EFO_0022232
Disease	angiopoietin-related protein 1 measurement	APOH UGT1A4	1.45e-03	18	93	2	EFO_0801382
Disease	Meckel syndrome type 1	RPGRIP1 RPGRIP1L	1.45e-03	18	93	2	C3714506
Disease	glomerulonephritis (is_marker_for)	FN1 KLKB1	1.62e-03	19	93	2	DOID:2921 (is_marker_for)
Disease	Colorectal Carcinoma	CPAMD8 ABCC4 FN1 CSMD3 ZEB2 ADCY8 KCNH4 OSBP	1.70e-03	702	93	8	C0009402
Disease	Neutropenia	UGT1A1 AP3D1	1.98e-03	21	93	2	C0027947
Disease	arginine measurement	CSMD1 KLKB1	2.38e-03	23	93	2	EFO_0020990
Disease	partial thromboplastin time	APOH KLKB1	2.59e-03	24	93	2	EFO_0004310
Disease	airway responsiveness measurement	ABCC4 CSMD1	2.59e-03	24	93	2	EFO_0006897
Disease	feeling nervous measurement	MGAM MADD CSMD1	2.65e-03	87	93	3	EFO_0009597
Disease	serum albumin measurement	HIVEP1 PEPD TMEM63B TCIRG1 APOH MADD CD44	2.70e-03	592	93	7	EFO_0004535
Disease	TEMPS-A questionnaire	DYNC2H1 CSMD1	2.81e-03	25	93	2	EFO_0004783
Disease	fasting blood glucose measurement, HOMA-B, fasting blood insulin measurement	MADD CD44	2.81e-03	25	93	2	EFO_0004465, EFO_0004466, EFO_0004469
Disease	serum metabolite measurement	TDRD15 ABCC4 TESPA1 UGT1A4 UGT1A1 LRPPRC ADRA1D CSMD1 KLKB1	2.97e-03	945	93	9	EFO_0005653
Disease	metabolic disease, COVID-19	FECH ARAP2	3.04e-03	26	93	2	EFO_0000589, MONDO_0100096
Disease	psychosis predisposition measurement	CD44 CSMD1	3.04e-03	26	93	2	EFO_0008337

Protein segments in the cluster

Peptide	Gene	Start	Entry
NSSAVFTDICSYPEY	ADCY8	821	P40145
FYCPHSGFTATIYDT	CATSPERG	286	Q6ZRH7
RYTTFEYPNTISFSC	APOH	96	P02749
EYPNTISFSCNTGFY	APOH	101	P02749
SDYSVGQSVSFECYP	CSMD1	2101	Q96PZ7
SFIYQSEVSFSCNFP	CSMD3	3306	Q7Z407
CYFPSVEYTATDANV	TBC1D32	986	Q96NH3
AVAFTFPFITTVTCY	GPR17	226	Q13304
YTDLSTDTFVCNCPY	DLL4	496	Q9NR61
PCFTTALSFYDGYRH	PGD	421	P52209
SSQAISPYACFYGAS	ARAP2	466	Q8WZ64
TESSGFLAYYEICQF	CHI3L2	296	Q15782
SYLITTPCYSDAFAK	AP3D1	1046	O14617
YYCFASDITCSFPAN	PEPD	281	P12955
LFAKSSTFYNPCIYV	RRH	281	O14718
YFLSSLSFLDFCYSS	OR8D4	61	Q8NGM9
YLFLSALSFSETCYT	OR10X1	76	Q8NGY0
TISSLQPEDFATYYC	IGKV1D-39	96	P04432
SHYPFFSTFRECLYT	MADD	181	Q8WXG6
TISSLQPEDFATYYC	IGKV1D-12	96	P01611
TFCTYAFYDFELQTT	RPGRIP1L	631	Q68CZ1
SECGFTYFISVFVYN	FNDC7	341	Q5VTL7
TISSLQPEDFATYYC	IGKV1D-43	96	A0A0B4J1Z2
TSAVDIFSAGCVFYY	ERN2	701	Q76MJ5
SGVPFCYFVNDLYSV	MGAM	991	O43451
SSGVPFCYFVNDLYS	MGAM	1886	O43451
TISSLQPEDFATYYC	IGKV1D-13	96	A0A0B4J2D9
YYETSSLCSQPAVVF	CCL4	51	P13236
VYSATTECVYPTSFI	MUC3A	121	Q02505
QYSFSTDTVECRFYS	PRF1	166	P14222
CSISSYFIIGYTAFI	ABCC11	291	Q96J66
DVFFYNSPTYCQTIV	DDHD2	306	O94830
ATFYVAVTVPYNVCF	KCNH4	236	Q9UQ05
TISSLQPEDFATYYC	IGKV1D-17	96	A0A075B6S4
TYTDYVIPCFDSVNS	LRPPRC	476	P42704
VSNCCFDPIVYYFTS	LPAR6	281	P43657
TLNSCVDPFVYYFSS	GPR42	266	O15529
CLTYSKAVADPFTYS	GPR78	281	Q96P69
EQLCYVAAFTVSSYS	OSBP	471	P22059
SFNYAFSYPVTSCGI	OOSP4B	51	A0A2R8Y4Y8
DYVVYSSVCSFFLPC	DRD4	191	P21917
YGFLFILSFSESCYT	OR10T2	61	Q8NGX3
TCESSSPFQLYYFIS	F2RL2	251	O00254
LNTAYAYATVLTFCT	ABCC4	131	O15439
VDDYSHYFFTPCILT	DYNC2H1	2486	Q8NCM8
IYSCVYYLDSTPFAA	IGSF1	1131	Q8N6C5
YYETSSLCSQPAVVF	CCL4L1	51	Q8NHW4
TALEQCFYCLYSFPS	CABIN1	941	Q9Y6J0
YSVIENSALAFYTSC	BRCA2	1661	P51587
CYNTVISPIYFVSFV	CACNA1G	1821	O43497
TSQYDTYCFNASAPP	CD44	111	P16070
SCYFNSSFTSIWIPY	GHR	111	P10912
PTYTVDIFSAGCVFY	ERN1	751	O75460
VLPFTYNGRTFYSCT	FN1	361	P02751
YFSVKSTCPCNFTLY	CPAMD8	471	Q8IZJ3
CFSALLPTIVYYSAF	TMEM63B	486	Q5T3F8
TLNSCVDPFVYYFSS	FFAR3	266	O14843
SCTYYMPEFSTVSSF	HOXC11	36	O43248
CTYHPNCLFFTFYTN	KLKB1	231	P03952
TISSLQPDDFATYYC	IGKV1-5	96	P01602
TISSLQPEDFATYYC	IGKV1-6	96	A0A0C4DH72
TISSLQPEDFATYYC	IGKV1-9	96	A0A0C4DH69
TISSLQPEDFATYYC	IGKV1-12	96	A0A0C4DH73
TISSLQPEDFATYYC	IGKV1-13	96	P0DP09
TISSLQPEDFATYYC	IGKV1-16	96	P04430
TISSLQPEDFATYYC	IGKV1-17	96	P01599
TISSLQPEDFATYYC	IGKV1-39	96	P01597
IAFTQYPQYSCSTTG	FECH	186	P22830
YINDYFCDQSLSTPF	DNAH2	4061	Q9P225
FSCLFLYTSELYPTV	SLC22A8	426	Q8TCC7
SDYCPFLCSSDSTYQ	OTOG	2366	Q6ZRI0
VYSATTECVYPTSFI	MUC3B	121	Q9H195
NTSYYIFTQCPDGAF	GTF2F1	121	P35269
GDTQPTTFCTYSFYD	RPGRIP1	646	Q96KN7
YSFYDFETHCTPLSV	RPGRIP1	656	Q96KN7
LSETFPSLFSLYSYC	TDRD15	941	B5MCY1
PSLFSLYSYCYSSFN	TDRD15	946	B5MCY1
CVFPSSAATYYPFVQ	SECISBP2	41	Q96T21
CSYPYHTLSQSSDEF	SAMD14	301	Q8IZD0
TVCAPGSYVDYFSSS	HRC	671	P23327
DYFLTISGNYLPSCF	OCRL	666	Q01968
FFVYYTHPASCSENK	SERINC1	216	Q9NRX5
CPAYATCTNTVDSYY	ADGRE1	41	Q14246
EAGYAVFSSVCSFYL	ADRA1D	251	P25100
LASGTTLFCTSFYYQ	TMEM256	71	Q8N2U0
TLFCTSFYYQALSGD	TMEM256	76	Q8N2U0
YEQCSTAFPAYSSTL	ZNF441	226	Q8N8Z8
FSLAQYYCSKTPASF	TBC1D23	276	Q9NUY8
AFSQNFLCDVVYSPY	UGT1A1	216	P22309
CFYHYTEAEGTFSSP	VIPAS39	341	Q9H9C1
QFYPFLYNITSSVCS	TTC17	736	Q96AE7
SVFTALFYCPGVYAN	ZDHHC23	331	Q8IYP9
NFLTSYSPFSYYTAC	TXNDC11	521	Q6PKC3
YSPFSYYTACCRTIS	TXNDC11	526	Q6PKC3
SSGPQSQTYYICFDT	PHLPP1	606	O60346
ADAFFCLYSYVSKTP	TESPA1	231	A2RU30
CSVFFNYSQASQPYT	TCHHL1	846	Q5QJ38
FSCPLCSYTFAYRTQ	ZEB2	241	O60315
ESASLYFTCTLYPEA	TG	1911	P01266
TDVRPYHCTYCNFSF	HIVEP1	2111	P15822
TFLLPAEYAEFCNSY	TTLL5	156	Q6EMB2
YTGFIYNECFSRATS	TCIRG1	456	Q13488
CETFQTYSGPYSISQ	ZMAT1	446	Q5H9K5
SYICHTFSAPYASLA	UGT1A4	221	P22310
ATFYVAVTVPYNVCF	KCNH8	231	Q96L42
TISSLQPEDFATYYC	IGKV1D-16	96	P01601
VFACSAVPVYIYFNT	PLP1	166	P60201