Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Anaphylatoxin_comp_syst	C4A C4B C5	8.39e-06	5	178	3	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B C5	8.39e-06	5	178	3	IPR001840
Domain	DEAH_ATP_HELICASE	EP400 WRN CHD8 CHD6 DHX34	2.89e-05	38	178	5	PS00690
Domain	ANATO	C4A C4B C5	2.90e-05	7	178	3	SM00104
Domain	ANAPHYLATOXIN_2	C4A C4B C5	2.90e-05	7	178	3	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B C5	2.90e-05	7	178	3	PS01177
Domain	ANATO	C4A C4B C5	2.90e-05	7	178	3	PF01821
Domain	Anaphylatoxin/fibulin	C4A C4B C5	2.90e-05	7	178	3	IPR000020
Domain	A2M	C4A C4B C5	9.72e-05	10	178	3	PF00207
Domain	A2M_N_2	C4A C4B C5	9.72e-05	10	178	3	IPR011625
Domain	A2M_comp	C4A C4B C5	9.72e-05	10	178	3	IPR011626
Domain	A2M_recep	C4A C4B C5	9.72e-05	10	178	3	PF07677
Domain	A2M_comp	C4A C4B C5	9.72e-05	10	178	3	PF07678
Domain	A2M_N	C4A C4B C5	9.72e-05	10	178	3	PF01835
Domain	A2M_N	C4A C4B C5	9.72e-05	10	178	3	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B C5	9.72e-05	10	178	3	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B C5	9.72e-05	10	178	3	PS00477
Domain	A2M_N_2	C4A C4B C5	9.72e-05	10	178	3	PF07703
Domain	Macroglobln_a2	C4A C4B C5	9.72e-05	10	178	3	IPR001599
Domain	SANT	MTA2 EP400 CHD6 DNAJC1 RERE	1.11e-04	50	178	5	SM00717
Domain	BAH	MTA2 TNRC18 RERE	1.33e-04	11	178	3	PS51038
Domain	BAH_dom	MTA2 TNRC18 RERE	1.33e-04	11	178	3	IPR001025
Domain	BAH	MTA2 TNRC18 RERE	1.33e-04	11	178	3	SM00439
Domain	BAH	MTA2 TNRC18 RERE	1.33e-04	11	178	3	PF01426
Domain	SANT/Myb	MTA2 EP400 CHD6 DNAJC1 RERE	1.34e-04	52	178	5	IPR001005
Domain	-	EP400 DYNC2H1 ATAD5 MTG2 WRN CARD10 CHD8 RAB40A RFC3 DCK NLRP2 RHOBTB1 RHOBTB2 RAB40AL HELZ CHD6 CHST7 DHX34	2.85e-04	746	178	18	3.40.50.300
Domain	CNH	CIT CDC42BPB MAP4K5	2.87e-04	14	178	3	SM00036
Domain	DNA/RNA_helicase_DEAH_CS	EP400 CHD8 CHD6 DHX34	3.32e-04	35	178	4	IPR002464
Domain	CNH	CIT CDC42BPB MAP4K5	3.56e-04	15	178	3	PF00780
Domain	CNH	CIT CDC42BPB MAP4K5	3.56e-04	15	178	3	PS50219
Domain	CNH_dom	CIT CDC42BPB MAP4K5	3.56e-04	15	178	3	IPR001180
Domain	MYB_LIKE	MTA2 EP400 DNAJC1 RERE	4.57e-04	38	178	4	PS50090
Domain	P-loop_NTPase	MYH7 EP400 DYNC2H1 ATAD5 MTG2 WRN CARD10 CHD8 RAB40A RFC3 DCK NLRP2 RHOBTB1 RHOBTB2 RAB40AL HELZ CHD6 CHST7 DHX34	4.83e-04	848	178	19	IPR027417
Domain	C345C	C4A C4B C5	5.25e-04	17	178	3	SM00643
Domain	G8_domain	CEMIP2 CEMIP	5.35e-04	4	178	2	IPR019316
Domain	G8	CEMIP2 CEMIP	5.35e-04	4	178	2	PS51484
Domain	G8	CEMIP2 CEMIP	5.35e-04	4	178	2	SM01225
Domain	G8	CEMIP2 CEMIP	5.35e-04	4	178	2	PF10162
Domain	-	C4A C5	5.35e-04	4	178	2	1.20.91.20
Domain	Terpenoid_cyclase/PrenylTrfase	C4A C4B C5	6.25e-04	18	178	3	IPR008930
Domain	NTR	C4A C4B C5	7.37e-04	19	178	3	PF01759
Domain	Netrin_module_non-TIMP	C4A C4B C5	7.37e-04	19	178	3	IPR018933
Domain	3'-5'_exonuclease_dom	WRN EXD3	8.86e-04	5	178	2	IPR002562
Domain	35EXOc	WRN EXD3	8.86e-04	5	178	2	SM00474
Domain	DNA_pol_A_exo1	WRN EXD3	8.86e-04	5	178	2	PF01612
Domain	NTR	C4A C4B C5	1.31e-03	23	178	3	PS50189
Domain	Netrin_domain	C4A C4B C5	1.31e-03	23	178	3	IPR001134
Domain	BRK	CHD8 CHD6	1.32e-03	6	178	2	SM00592
Domain	BRK_domain	CHD8 CHD6	1.32e-03	6	178	2	IPR006576
Domain	Cu_oxidase_Cu_BS	F5 SNAI3	1.32e-03	6	178	2	IPR002355
Domain	BRK	CHD8 CHD6	1.32e-03	6	178	2	PF07533
Domain	TIMP-like_OB-fold	C4A C4B C5	1.88e-03	26	178	3	IPR008993
Domain	SANT_dom	MTA2 DNAJC1 RERE	1.88e-03	26	178	3	IPR017884
Domain	SANT	MTA2 DNAJC1 RERE	2.34e-03	28	178	3	PS51293
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	2.44e-03	8	178	2	IPR019565
Domain	N6_MTASE	TRMT11 MGAM2	2.44e-03	8	178	2	PS00092
Domain	Pectin_lyase_fold/virulence	CEMIP2 CEMIP	2.44e-03	8	178	2	IPR011050
Domain	Thiol-ester_cl	C4A C4B	2.44e-03	8	178	2	PF10569
Domain	MacrogloblnA2_CS	C4A C4B	2.44e-03	8	178	2	IPR019742
Domain	A2M_N_2	C4A C5	2.44e-03	8	178	2	SM01359
Domain	-	C4A C5	2.44e-03	8	178	2	2.60.40.690
Domain	A2M_recep	C4A C5	2.44e-03	8	178	2	SM01361
Domain	A2M	C4A C5	2.44e-03	8	178	2	SM01360
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C4A C4B C5	2.80e-05	7	133	3	MM14685
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C4A C4B C5	4.44e-05	8	133	3	M27031
Pathway	BIOCARTA_LECTIN_PATHWAY	C4A C4B C5	1.28e-04	11	133	3	MM1430
Pathway	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	VGF F5 ITIH2 C4A C4B LTBP1 APOL2	1.39e-04	120	133	7	MM14982
Pathway	BIOCARTA_CLASSIC_PATHWAY	C4A C4B C5	1.70e-04	12	133	3	MM1368
Pathway	BIOCARTA_LECTIN_PATHWAY	C4A C4B C5	2.19e-04	13	133	3	M4732
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ANKRD13D MTA2 RANBP10 NDOR1 EP400 MTG2 PIEZO1 POLR2A OBSCN TRMT11 CARD10 CHD8 BCR CIT CDC42BPB RYR1 SIL1 UNC119 KMT2C TNRC18 KANSL1 CD2BP2 HPS6 NCAPD2 ANKRD34A NLE1 CHPF DHX34	7.02e-12	1105	184	28	35748872
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MTA2 FNDC3B CCDC22 EP400 SMCHD1 POLR2A CHD8 SSBP1 RFC3 DCK SLC25A3 KANSL1 RACK1 GTF3C2 BAZ2A MICAL2 MAP4K5 NCAPD2 BYSL SAFB2 FIP1L1 NLE1 DHX34 UTRN RPL4 ZMYM3	1.41e-08	1353	184	26	29467282
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	MTA2 MYH7 EP400 DYNC2H1 PSKH1 SMCHD1 POLR2A CARD10 SSBP1 RFC3 BCR PNPT1 RHOBTB1 RACK1 HPS6 BYSL SAFB2 CHD6	1.24e-07	754	184	18	35906200
Pubmed	Mouse complement component C4 is devoid of classical pathway C5 convertase subunit activity.	C4A C4B C5	1.46e-07	3	184	3	8649451
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	EP400 JADE3 SMCHD1 PIEZO1 CHD8 ANKRD50 RGP1 BCR CEMIP2 KMT2C GTF3C2 NRXN2 NCAPD2 CPNE1 DHX34	1.68e-07	529	184	15	14621295
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	MTA2 CCDC22 EP400 SMCHD1 POLR2A CHD8 ZNF318 SLC25A3 KMT2C RACK1 GTF3C2 BAZ2A PGRMC2 NCAPD2 PEAK1	2.70e-07	549	184	15	38280479
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MTA2 SMCHD1 POLR2A CHD8 ZNF318 PNPT1 RACK1 BAZ2A NCAPD2 BYSL NLE1 HELZ UTRN RPL4 FKBP4 ZMYM3	4.56e-07	653	184	16	22586326
Pubmed	Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.	FNBP1 PSKH1 NKX3-2 CARD10 SSBP1 IDE RFC3 ANGPTL1 FZD8 CDH22 RLIM BYSL KCNQ3 USP35 C5 TRAPPC14 APOL2 DHX34	5.20e-07	832	184	18	36724073
Pubmed	Impaired mast cell-dependent natural immunity in complement C3-deficient mice.	C4A C4B C5	5.80e-07	4	184	3	9367154
Pubmed	Phylogeny of the C3/C4/C5 complement-component gene family indicates that C5 diverged first.	C4A C4B C5	5.80e-07	4	184	3	8015436
Pubmed	Role of complement receptors 1 and 2 (CD35 and CD21), C3, C4, and C5 in survival by mice of Staphylococcus aureus bacteremia.	C4A C4B C5	1.45e-06	5	184	3	15192652
Pubmed	A role for Mac-1 (CDIIb/CD18) in immune complex-stimulated neutrophil function in vivo: Mac-1 deficiency abrogates sustained Fcgamma receptor-dependent neutrophil adhesion and complement-dependent proteinuria in acute glomerulonephritis.	ICAM1 C4A C4B	1.45e-06	5	184	3	9382884
Pubmed	Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies.	C4A C4B C5	1.45e-06	5	184	3	17200182
Pubmed	Predominant role for C5b-9 in renal ischemia/reperfusion injury.	C4A C4B C5	1.45e-06	5	184	3	10811844
Pubmed	Intranasal peptide-induced tolerance and linked suppression: consequences of complement deficiency.	C4A C4B C5	1.45e-06	5	184	3	25039245
Pubmed	Formation of high affinity C5 convertase of the classical pathway of complement.	C4A C4B C5	1.45e-06	5	184	3	12878586
Pubmed	Intraflagellar transport, cilia, and mammalian Hedgehog signaling: analysis in mouse embryonic fibroblasts.	DYNC2H1 IFT172 SHH	1.45e-06	5	184	3	18488998
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	MTA2 EP400 SMCHD1 POLR2A CHD8 GTF3C2 HPS6 NCAPD2 SAFB2 RPL4 ZMYM3	1.77e-06	332	184	11	32786267
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FNBP1 EP400 IFT172 NCDN TENM4 KANSL1 BAZ2A RHOBTB2 CHD6 RERE RUBCN ZMYM3	2.01e-06	407	184	12	12693553
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	FNDC3B PPFIBP1 CHD8 GMIP ANKRD50 BCR NCDN CEMIP2 CEMIP HELZ C4A C4B RBM47 DHX34 RUBCN	2.20e-06	650	184	15	38777146
Pubmed	Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: role of factor B and factor H.	C4A C4B C5	2.88e-06	6	184	3	16849499
Pubmed	Complexity at the mouse minor histocompatibility locus H-4.	TYR C4A C4B	2.88e-06	6	184	3	2137109
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	EP400 TRPM7 PPFIBP1 WRN ZNF318 ANKRD50 RFC3 NDRG3 CDC42BPB PPL CEMIP2 RACK1 SLITRK5 FIP1L1 PEAK1 RPL4	4.29e-06	777	184	16	35844135
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	FNDC3B EP400 ATAD5 PPFIBP1 PIEZO1 POLR2A WRN CHD8 ZNF318 CIT CDC42BPB SLC25A3 KMT2C RACK1 GTF3C2 BAZ2A NCAPD2 BYSL HELZ CHD6 DNAJC1 UTRN ZMYM3	4.76e-06	1497	184	23	31527615
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	MTA2 NMNAT1 JADE3 ATAD5 SMCHD1 WRN CHD8 SSBP1 RFC3 GTF3C2 BAZ2A CHD6 PRDM15 ZMYM3	4.98e-06	608	184	14	36089195
Pubmed	Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome.	C4A C4B C5	5.02e-06	7	184	3	14660741
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	MTA2 EP400 JADE3 ATAD5 SMCHD1 POLR2A WRN ZNF318 RFC3 SLC25A3 KMT2C KANSL1 GTF3C2 BAZ2A CD2BP2 SAFB2 FIP1L1 CHD6 DNAJC1 RPL4 ZMYM3	5.57e-06	1294	184	21	30804502
Pubmed	C3 opsonization regulates endocytic handling of apoptotic cells resulting in enhanced T-cell responses to cargo-derived antigens.	C4A C4B C5	8.00e-06	8	184	3	24474777
Pubmed	The role of complement in cryoglobulin-induced immune complex glomerulonephritis.	C4A C4B C5	8.00e-06	8	184	3	16272350
Pubmed	Synergy between the classical and alternative pathways of complement is essential for conferring effective protection against the pandemic influenza A(H1N1) 2009 virus infection.	C4A C4B C5	8.00e-06	8	184	3	28301559
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	CCDC22 EP400 JADE3 ATAD5 SMCHD1 POLR2A CEP76 F5 GTF3C2 FIP1L1 LTBP1 CHD6 PRDM15 UTRN	9.70e-06	645	184	14	25281560
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	MTA2 EP400 NMNAT1 SMCHD1 ICAM1 WRN SSBP1 RFC3 CDC42BPB ITIH2 SLC25A3 PNPT1 RCC1L RACK1 CD2BP2 PGRMC2 CPNE1 FIP1L1 C4B C5 RBM47	1.33e-05	1371	184	21	36244648
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	TRPM7 DYNC2H1 ATAD5 PPFIBP1 PIEZO1 SSBP1 CDC42BPB NCDN CEMIP2 PNPT1 GTF3C2 BAZ2A MAP4K5 PGRMC2 BYSL MRPS6 NLE1 CCDC97 DNAJC1 PEAK1 RPL4 FKBP4	1.40e-05	1487	184	22	33957083
Pubmed	Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling.	C4A C4B C5	1.70e-05	10	184	3	30429287
Pubmed	The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking.	DYNC2H1 IFT172 SHH	2.33e-05	11	184	3	22689656
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	2.78e-05	2	184	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	2.78e-05	2	184	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	2.78e-05	2	184	2	15998580
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	2.78e-05	2	184	2	19062096
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	2.78e-05	2	184	2	19933335
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	2.78e-05	2	184	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	2.78e-05	2	184	2	17645767
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	2.78e-05	2	184	2	12207352
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	2.78e-05	2	184	2	27758680
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	2.78e-05	2	184	2	22387014
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	2.78e-05	2	184	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	2.78e-05	2	184	2	23918728
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	2.78e-05	2	184	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	2.78e-05	2	184	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	2.78e-05	2	184	2	4216347
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	2.78e-05	2	184	2	6950384
Pubmed	Vesicular trafficking through cortical actin during exocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activating protein Gem-interacting protein.	GMIP SYTL1	2.78e-05	2	184	2	22438581
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	2.78e-05	2	184	2	8660986
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	2.78e-05	2	184	2	8428773
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	2.78e-05	2	184	2	24638111
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	2.78e-05	2	184	2	21345967
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	2.78e-05	2	184	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	2.78e-05	2	184	2	2302180
Pubmed	Single-nucleotide variants in two Hedgehog genes, SHH and HHIP, as genetic cause of combined pituitary hormone deficiency.	SHH HHIP	2.78e-05	2	184	2	22897141
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	2.78e-05	2	184	2	22151770
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	2.78e-05	2	184	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	2.78e-05	2	184	2	29080553
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	2.78e-05	2	184	2	6589636
Pubmed	The role and regulation of TMEM2 (transmembrane protein 2) in HYBID (hyaluronan (HA)-binding protein involved in HA depolymerization/ KIAA1199/CEMIP)-mediated HA depolymerization in human skin fibroblasts.	CEMIP2 CEMIP	2.78e-05	2	184	2	30241936
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	2.78e-05	2	184	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	2.78e-05	2	184	2	17728371
Pubmed	Structure and organization of the C4 genes.	C4A C4B	2.78e-05	2	184	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	2.78e-05	2	184	2	6149581
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	2.78e-05	2	184	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	2.78e-05	2	184	2	3542363
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	2.78e-05	2	184	2	2387317
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	2.78e-05	2	184	2	16908004
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	2.78e-05	2	184	2	7365238
Pubmed	Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.	C4A C4B	2.78e-05	2	184	2	7391573
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	2.78e-05	2	184	2	17971360
Pubmed	Clinical features of patients with homozygous complement C4A or C4B deficiency.	C4A C4B	2.78e-05	2	184	2	29928053
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	2.78e-05	2	184	2	17971229
Pubmed	Concurrent Overexpression of Two Hyaluronidases, KIAA1199 and TMEM2, Strongly Predicts Shorter Survival After Resection in Pancreatic Ductal Adenocarcinoma.	CEMIP2 CEMIP	2.78e-05	2	184	2	36395406
Pubmed	Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.	C4A C4B	2.78e-05	2	184	2	6881182
Pubmed	Partial C4 deficiency in juvenile idiopathic arthritis patients.	C4A C4B	2.78e-05	2	184	2	17921792
Pubmed	Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.	C4A C4B	2.78e-05	2	184	2	21880985
Pubmed	Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.	C4A C4B	2.78e-05	2	184	2	6978711
Pubmed	Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.	C4A C4B	2.78e-05	2	184	2	35898513
Pubmed	Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.	C4A C4B	2.78e-05	2	184	2	28873507
Pubmed	Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.	C4A C4B	2.78e-05	2	184	2	276882
Pubmed	Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling.	SHH HHIP	2.78e-05	2	184	2	34887403
Pubmed	Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.	C4A C4B	2.78e-05	2	184	2	6832377
Pubmed	Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.	C4A C4B	2.78e-05	2	184	2	3794341
Pubmed	Expression and regulation of recently discovered hyaluronidases, HYBID and TMEM2, in chondrocytes from knee osteoarthritic cartilage.	CEMIP2 CEMIP	2.78e-05	2	184	2	36241903
Pubmed	Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.	C4A C4B	2.78e-05	2	184	2	22785613
Pubmed	Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.	C4A C4B	2.78e-05	2	184	2	32691186
Pubmed	The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.	C4A C4B	2.78e-05	2	184	2	8390682
Pubmed	Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).	C4A C4B	2.78e-05	2	184	2	3902619
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	2.78e-05	2	184	2	7373044
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	2.78e-05	2	184	2	3696167
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	2.78e-05	2	184	2	1357031
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	2.78e-05	2	184	2	16098595
Pubmed	Targeting of ALK2, a Receptor for Bone Morphogenetic Proteins, Using the Cre/lox System to Enhance Osseous Regeneration by Adipose-Derived Stem Cells.	NDOR1 ACVR1	2.78e-05	2	184	2	25232183
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	2.78e-05	2	184	2	15787745
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	2.78e-05	2	184	2	30026462
Interaction	TOP3B interactions	ANKRD13D MTA2 RANBP10 NDOR1 EP400 MTG2 PIEZO1 POLR2A WRN OBSCN APBA1 TRMT11 CARD10 CHD8 SSBP1 BCR CIT CDC42BPB RYR1 SIL1 UNC119 KMT2C TNRC18 KANSL1 CD2BP2 HPS6 NCAPD2 BYSL ANKRD34A SAFB2 NLE1 HELZ CHPF RBM47 DHX34	8.03e-08	1470	180	35	int:TOP3B
Cytoband	Xp11.23	CCDC22 MAOB JADE3 PPP1R3F CHST7	4.24e-05	95	184	5	Xp11.23
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B C5	1.99e-05	9	114	3	1234
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	MTA2 EP400 CHD6 DNAJC1 RERE	2.06e-05	53	114	5	532
GeneFamily	WD repeat domain containing	IFT172 EIPR1 DCAF12L2 RACK1 GTF3C2 DCAF12L1 NLE1	1.37e-03	262	114	7	362
GeneFamily	Complement system\|Sushi domain containing	C4A C4B C5	1.50e-03	36	114	3	492
GeneFamily	Oxysterol binding proteins\|Pleckstrin homology domain containing	OSBPL7 OSBPL6	2.50e-03	12	114	2	670
GeneFamily	PHD finger proteins	JADE3 PHF1 KMT2C BAZ2A	2.53e-03	90	114	4	88
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FNDC3B PDSS1 HDHD5 SHH BCL6 RGP1 MICAL2 DHX34	3.53e-07	160	184	8	70f3637dd0bcfcef421aa114f946fff0048f192e
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	ABAT WRN NCDN CEMIP KMT2C EXD3 C2orf42 PRDM15	7.92e-07	178	184	8	536a601abcc60867949ea06e9aafb6c7b799b56b
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD13D EPHB3 NDOR1 KANSL1 C4A C4B RUBCN	8.13e-07	123	184	7	a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FNBP1 FNDC3B KMT2C KANSL1 RERE RBM47 UTRN PIK3R5	1.45e-06	193	184	8	779276e775cb2492e8dd36436295a536084a6415
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MAB21L4 HAO1 BCL6 GIPR FCGBP ZBTB32 MUC4	2.56e-06	146	184	7	d33bd571c2adf5f89e6f02e77d094c19edd4729c
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	C15orf62 MAB21L4 PPL FZD8 SORCS2 ILDR1 MUC4	8.14e-06	174	184	7	9e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPHB3 MAB21L4 SHH HPS6 ROM1 C1QTNF4 RBM47	8.45e-06	175	184	7	96219e58dcb327fd27190be78193e7a0d611e62b
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPHB3 MAB21L4 SHH HPS6 ROM1 C1QTNF4 RBM47	8.45e-06	175	184	7	cb974fbebe8cb58c7d3f7defabb4e056f2fee5fa
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ATAD5 SMCHD1 EIPR1 RFC3 DCK CIT NCAPD2	8.77e-06	176	184	7	9e719e6323597ecfc758c957256872cd4ae24d4d
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	WRN NCDN CEMIP KMT2C C2orf42 LTBP1 PRDM15	9.10e-06	177	184	7	eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	WRN NCDN CEMIP EXD3 C2orf42 LTBP1 PRDM15	9.45e-06	178	184	7	9d575902d3dbe33437c9d4200df093a741269803
ToppCell	Hippocampus-Neuronal-Inhibitory\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ABAT COL19A1 SHH ANKRD50 CIT UNC119 CHD6	1.09e-05	182	184	7	b54ae650c04dfd0759c5f5e752b9bf684dd36516
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	SMCHD1 ICAM1 CHD8 PNPT1 KMT2C APOL2 UTRN	1.13e-05	183	184	7	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	renal_medulla_nuclei-Adult_normal_reference\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	BCL6 KANSL1 SORCS2 MRPS6 LTBP1 RERE UTRN	1.44e-05	190	184	7	f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell	Transverse-T_cell-Tfh\|T_cell / Region, Cell class and subclass	PDSS1 ICAM1 OBSCN APBA1 ZNF318 MIPEP BYSL	1.94e-05	199	184	7	33ffea12b8228e0b5bd8942531c3b21d24224725
ToppCell	metastatic_Brain-Myeloid_cells-CD1c+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	NDOR1 GIPR NRXN2 CYP26C1 SLITRK5 SYTL1	2.78e-05	142	184	6	1eecbec805a873fa3539df0574670cf73c18c7b1
Drug	NU1025; Up 200; 100uM; MCF7; HG-U133A	RANBP10 NDOR1 GMIP RGP1 SIL1 BAZ2A OSBPL7 PRRG3 UTRN POFUT2	3.66e-06	194	181	10	608_UP
Drug	Ganciclovir [82410-32-0]; Down 200; 15.6uM; HL60; HT_HG-U133A	ABAT CCDC22 RGP1 NDRG3 F5 SLITRK5 DNAJC1 C5 APOL2 DHX34	4.20e-06	197	181	10	3030_DN
Drug	Moxisylyte hydrochoride [964-52-3]; Down 200; 12.6uM; MCF7; HT_HG-U133A	DYNC2H1 ATAD5 PSKH1 NDRG3 NCDN CEMIP2 MICAL2 SAFB2 HELZ LTBP1	4.80e-06	200	181	10	7015_DN
Disease	developmental and epileptic encephalopathy 64 (implicated_via_orthology)	RHOBTB1 RHOBTB2	3.54e-05	2	176	2	DOID:0070375 (implicated_via_orthology)
Disease	uric acid measurement	TRPM7 DYNC2H1 ZNF318 ACVR1 ANKRD50 DCAF12L2 F5 CEMIP NRXN2 MAP4K5 MRPS6 ILDR1 ZMYM3	8.15e-05	610	176	13	EFO_0004761
Disease	creatinine measurement	GRK7 OBSCN SHH CARD10 TUB RYR1 CEMIP GIPR DCAF12L1 NRXN2 MAP4K5 CYP26C1 MRPS6 FIP1L1 ILDR1 APOL2 RBM47	1.02e-04	995	176	17	EFO_0004518
Disease	Anorectal Malformations	FNBP1 SIL1 HHIP FAM110B	1.04e-04	41	176	4	C3495676
Disease	systemic lupus erythematosus (implicated_via_orthology)	MTA2 C4A C4B RUBCN	1.26e-04	43	176	4	DOID:9074 (implicated_via_orthology)
Disease	Infiltrating duct carcinoma of female breast	TRPM7 CDC42BPB EPHA10	2.56e-04	21	176	3	C3165106
Disease	Colorectal Carcinoma	HK3 TRPM7 AMACR WRN OBSCN F5 NT5C NCDN KMT2C HHIP CDH22 PIK3R5 FAM110B	3.21e-04	702	176	13	C0009402
Disease	level of Phosphatidylcholine (15:0_18:1) in blood serum	GTF3C2 MAP4K5	3.50e-04	5	176	2	OBA_2045064
Disease	urate measurement, bone density	FNBP1 PPFIBP1 MTG2 DCK PPL GIPR RHOBTB1 MAP4K5 RHOBTB2 MIPEP PEAK1 UTRN	3.63e-04	619	176	12	EFO_0003923, EFO_0004531
Disease	Flaccid Muscle Tone	ABAT KANSL1	5.22e-04	6	176	2	C0026825
Disease	Neonatal Hypotonia	ABAT KANSL1	5.22e-04	6	176	2	C2267233
Disease	VACTERL association (implicated_via_orthology)	DYNC2H1 IFT172	5.22e-04	6	176	2	DOID:14679 (implicated_via_orthology)
Disease	Congenital myopathy with fiber type disproportion	MYH7 RYR1	5.22e-04	6	176	2	cv:C0546264
Disease	Muscle Tone Atonic	ABAT KANSL1	5.22e-04	6	176	2	C0427202
Disease	Floppy Muscles	ABAT KANSL1	5.22e-04	6	176	2	C0427201
Disease	Unilateral Hypotonia	ABAT KANSL1	5.22e-04	6	176	2	C0751330
Disease	level of Phosphatidylcholine (16:0_18:1) in blood serum	GTF3C2 MAP4K5	5.22e-04	6	176	2	OBA_2045070
Disease	level of Phosphatidylcholine (16:1_18:0) in blood serum	GTF3C2 MAP4K5	5.22e-04	6	176	2	OBA_2045081
Disease	hearing loss	ZNF318 TUB TYR ILDR1	7.00e-04	67	176	4	EFO_0004238
Disease	CHARGE syndrome (implicated_via_orthology)	CHD8 CHD6	7.28e-04	7	176	2	DOID:0050834 (implicated_via_orthology)
Disease	loneliness measurement	PHF1 EXD3 RERE UTRN FAM110B	9.06e-04	124	176	5	EFO_0007865
Disease	triacylglycerol 51:2 measurement	GTF3C2 MAP4K5	9.67e-04	8	176	2	EFO_0021483
Disease	level of Triacylglycerol (49:2) in blood serum	GTF3C2 MAP4K5	9.67e-04	8	176	2	OBA_2045162
Disease	diffuse large B-cell lymphoma (is_marker_for)	ICAM1 BCL6	9.67e-04	8	176	2	DOID:0050745 (is_marker_for)
Disease	Complement deficiency disease	C4A C4B C5	9.98e-04	33	176	3	C0272242
Disease	Autistic Disorder	ABAT MAOB MARK1 CHD8 NRXN2 C4B IL5	1.01e-03	261	176	7	C0004352
Disease	serum urea measurement	ZNF318 BCL6 GIPR MAP4K5 ILDR1 RBM47	1.15e-03	195	176	6	EFO_0009795
Disease	Prostatic Neoplasms	AMACR ICAM1 HAO1 PPL SIL1 KMT2C BAZ2A RLIM CHD6 MUC4 ZMYM3	1.24e-03	616	176	11	C0033578
Disease	Malignant neoplasm of prostate	AMACR ICAM1 HAO1 PPL SIL1 KMT2C BAZ2A RLIM CHD6 MUC4 ZMYM3	1.24e-03	616	176	11	C0376358
Disease	Facies	CHD8 RAB40AL	1.54e-03	10	176	2	C0282631
Disease	otitis media (is_marker_for)	ICAM1 MUC4	1.54e-03	10	176	2	DOID:10754 (is_marker_for)
Disease	allergic conjunctivitis (is_marker_for)	ICAM1 MUC4	1.54e-03	10	176	2	DOID:11204 (is_marker_for)
Disease	Graves' disease (is_implicated_in)	ICAM1 C4A C4B	1.63e-03	39	176	3	DOID:12361 (is_implicated_in)
Disease	Jeune thoracic dystrophy	DYNC2H1 IFT172	1.88e-03	11	176	2	C0265275
Disease	liver cirrhosis (is_implicated_in)	ICAM1 F5 C5	2.16e-03	43	176	3	DOID:5082 (is_implicated_in)
Disease	progression free survival, urinary bladder cancer	SHH TENM4	2.24e-03	12	176	2	EFO_0004920, MONDO_0001187
Disease	left ventricular systolic function measurement	OBSCN TUB GIPR	2.31e-03	44	176	3	EFO_0008206
Disease	diastolic blood pressure, systolic blood pressure	FNDC3B RANBP10 DYNC2H1 SHH BCL6 CEMIP PNPT1 TENM4 OSBPL6 FIP1L1 CHD6	2.39e-03	670	176	11	EFO_0006335, EFO_0006336
Disease	Gastric Adenocarcinoma	TRPM7 MARK1 EPHA10	2.46e-03	45	176	3	C0278701
Disease	Autosomal Dominant Myotubular Myopathy	MYH7 RYR1	2.64e-03	13	176	2	C3661489
Disease	Centronuclear myopathy	MYH7 RYR1	2.64e-03	13	176	2	C0175709
Disease	X-linked centronuclear myopathy	MYH7 RYR1	2.64e-03	13	176	2	C0410203
Disease	Short Rib-Polydactyly Syndrome	DYNC2H1 IFT172	2.64e-03	13	176	2	C0036996
Disease	Myopathy, Centronuclear, 1	MYH7 RYR1	2.64e-03	13	176	2	C4551952
Disease	Vitiligo, response to rhododendrol	COL19A1 MICAL2	2.64e-03	13	176	2	EFO_0004208, EFO_0010824
Disease	Congenital Structural Myopathy	MYH7 RYR1	2.64e-03	13	176	2	C0752282
Disease	IGF-1 measurement	FNDC3B MARK1 ICAM1 TRMT11 PHF1 HHIP MAP4K5 CYP26C1 SORCS2	2.75e-03	488	176	9	EFO_0004627
Disease	skin melanoma (is_implicated_in)	ICAM1 TYR	3.07e-03	14	176	2	DOID:8923 (is_implicated_in)
Disease	Myopathy, Centronuclear, Autosomal Dominant	MYH7 RYR1	3.07e-03	14	176	2	C1834558
Disease	Tubular Aggregate Myopathy	MYH7 RYR1	3.07e-03	14	176	2	C0410207
Disease	triacylglycerol 46:2 measurement	GTF3C2 MAP4K5	3.07e-03	14	176	2	EFO_0010402
Disease	Saldino-Noonan Syndrome	DYNC2H1 IFT172	3.07e-03	14	176	2	C0036069
Disease	Majewski Syndrome	DYNC2H1 IFT172	3.07e-03	14	176	2	C0024507
Disease	aspartate aminotransferase measurement	TRPM7 PIEZO1 OBSCN DCK SLC25A3 BAZ2A MAP4K5 RHOBTB2 OSBPL6 CPNE1 CCDC97 C1QTNF4 APOL2	3.13e-03	904	176	13	EFO_0004736
Disease	glucose homeostasis measurement, glucose effectiveness measurement	BCL6 MAP4K5	3.53e-03	15	176	2	EFO_0006833, EFO_0006896
Disease	brain edema (biomarker_via_orthology)	ICAM1 C5	3.53e-03	15	176	2	DOID:4724 (biomarker_via_orthology)
Disease	Autosomal Recessive Centronuclear Myopathy	MYH7 RYR1	3.53e-03	15	176	2	C3645536
Disease	Retinitis Pigmentosa	IFT172 TUB UNC119 ROM1	3.54e-03	104	176	4	C0035334
Disease	calcium/calmodulin-dependent protein kinase type 1 measurement	F5 CPNE1	4.02e-03	16	176	2	EFO_0008062
Disease	diacylglycerol 44:7 measurement	IFT172 MAP4K5	4.02e-03	16	176	2	EFO_0020069
Disease	primary autosomal recessive microcephaly (is_implicated_in)	NCAPD2 TRAPPC14	4.02e-03	16	176	2	DOID:0070296 (is_implicated_in)
Disease	Muscle hypotonia	ABAT KANSL1	4.54e-03	17	176	2	C0026827
Disease	glycochenodeoxycholate measurement	ANKRD13D CEMIP	4.54e-03	17	176	2	EFO_0010490
Disease	Antibody Deficiency Syndrome	C4A C5	4.54e-03	17	176	2	C0003257
Disease	triacylglycerol 48:1 measurement	GTF3C2 MAP4K5	4.54e-03	17	176	2	EFO_0010404
Disease	IGF-1 measurement, IGFBP-3 measurement	MAP4K5 SORCS2	4.54e-03	17	176	2	EFO_0004626, EFO_0004627
Disease	level of Phosphatidylcholine (14:0_18:2) in blood serum	GTF3C2 MAP4K5	4.54e-03	17	176	2	OBA_2045063
Disease	idiopathic pulmonary fibrosis	PSKH1 ZNF318 KANSL1	4.82e-03	57	176	3	EFO_0000768
Disease	lifestyle measurement, alcohol consumption measurement	CEMIP2 KCNQ3 DHX34 UTRN	5.06e-03	115	176	4	EFO_0007878, EFO_0010724
Disease	Congenital Fiber Type Disproportion	MYH7 RYR1	5.08e-03	18	176	2	C0546264
Disease	cholesteryl esters to total lipids in large HDL percentage	PSKH1 MAP4K5 CYP26C1	5.31e-03	59	176	3	EFO_0022248
Disease	asthma (biomarker_via_orthology)	ICAM1 SLC18A3 IL5	5.31e-03	59	176	3	DOID:2841 (biomarker_via_orthology)
Disease	response to antipsychotic drug	DYNC2H1 ZNF202 TENM4	5.56e-03	60	176	3	GO_0097332
Disease	complex trait	IFT172 HHIP GTF3C2 MAP4K5 LTBP1 CHD6	5.88e-03	271	176	6	EFO_0010578

Protein segments in the cluster

Peptide	Gene	Start	Entry
DLQVYSVRQRDRGPD	C2orf42	71	Q9NWW7
LEERPLTLYRGNSRN	ATAD5	1411	Q96QE3
SQYPDVVARERLAAR	ESX1	161	Q8N693
CRNRYENVIIPREEG	EP400	2421	Q96L91
AIRRARANPQLGAYA	APOL2	226	Q9BQE5
RDLDRGTVPNYQRAQ	CARD10	756	Q9BWT7
YERIDGRVRGNLRQA	CHD8	1176	Q9HCK8
YRQQREAVLGRAVPV	CCDC187	676	A0A096LP49
RDYQRATQRLAGIPE	ANKRD13D	96	Q6ZTN6
NPGQRVRYRVFALDQ	C4B	151	P0C0L5
DRAEEQRRHQDGLPY	BCR	441	P11274
YRDGNPRVRSLVQDT	AEBP1	646	Q8IUX7
AALEQNVERRYLREP	BAZ2A	1591	Q9UIF9
QRENPRLIYARLSGF	AMACR	96	Q9UHK6
RRNQERLNPRDVEYG	ACVR1	151	Q04771
GRSYENLLGREVREP	AJM1	466	C9J069
VQALAFDEQRRPGAR	C1QTNF4	101	Q9BXJ3
LGEEQRQLPERAFRA	GIPR	416	P48546
INQRRYPRATDGKEE	ANGPTL1	31	O95841
IDQRGYDGRNALRVA	ANKRD50	906	Q9ULJ7
PRQAARFVNVLGYER	CEP76	336	Q8TAP6
IREDYRALRQENAGL	CCDC22	606	O60826
NYQRDRLGRRPEIGV	C5orf52	36	A6NGY3
SERLVQYLNAVPDGR	CEMIP	216	Q8WUJ3
RRQRYDDILINGLPD	DNAJC1	121	Q96KC8
LIYDNEAREAGQRPV	CIT	1476	O14578
RYLLEQGADPNIADR	ANKRD34A	61	Q69YU3
LRGQDPERVTLQDYR	ZFYVE19	336	Q96K21
PVVQYVGERAARADR	RCC1L	46	Q96I51
GEQELSRRLQRLYPA	RANBP10	31	Q6VN20
VPREQAQAYAERLGV	RAB40A	136	Q8WXH6
VPREQAQAYAERLGV	RAB40AL	136	P0C0E4
RAVRELNNYEIRPGR	RBM47	126	A0AV96
RRAARRPYAPINANA	MTA2	476	O94776
VPLEQRRGFLAREQY	NT5C	36	Q8TCD5
TRDETNYGIPQRALR	RACK1	46	P63244
GDFRQRYRILNPAAI	MYH7	716	P12883
DRYLAIVRPVANARL	APLNR	126	P35414
ILTQYGRVLRQPVDR	MAOB	406	P27338
GRVLRQPVDRIYFAG	MAOB	411	P27338
YLQAIRSREAPRAQD	MAB21L4	21	Q08AI8
LQGLQFYRLHREERP	MUC4	4541	Q99102
LNSYNGRRDLEIERP	NDRG3	226	Q9UGV2
RFRGEQQLRRDYGPI	OGFOD2	31	Q6N063
QQLRRDYGPILRSRG	OGFOD2	36	Q6N063
RRPRNLAAAAVEEQY	SLC25A3	41	Q00325
QAYIELRHRAPDGRQ	KMT2C	2556	Q8NEZ4
LFRPRNGRNIEDEAQ	NMS	136	Q5H8A3
GRNPTLERYLGALRE	NCDN	31	Q9UBB6
VGDPENRLYDVRIQN	MGAM2	1031	Q2M2H8
VAENRRYQRSLPGES	ITIH2	46	P19823
PGNGDVYQERLARLE	PPFIBP1	96	Q86W92
PGQRYQEFVRALRPE	GMIP	341	Q9P107
RIQTLIYDALERPRG	KCNQ3	106	O43525
DLQARYPQFISRVRG	ABAT	421	P80404
PFEDDNRTRLYRQIL	PSKH1	296	P11801
RGYAVQRLPELLTER	DCAF12L2	76	Q5VW00
NRRYAALRELIQGGE	CCDC97	156	Q96F63
QEAVRAALSPLGRYR	PNMA6E	36	A0A0J9YXQ4
VTGRRQPYGRDALVD	LTBP1	1581	Q14766
SYQSELEALRRRGPQ	PPL	1211	O60437
EQLRQYDGSRNPRIL	PGRMC2	106	O15173
PQRQALYRGLENREE	PEAK1	1271	Q9H792
QDRYGRAESPDLRRL	FIP1L1	296	Q6UN15
TPYLGNRLDDVRNRF	HAO1	161	Q9UJM8
RGQNEPVLGVDYRQR	ILDR1	106	Q86SU0
DNERLAIARQRIPYR	NRXN2	1256	Q9P2S2
QSYELRAELLGRQPV	KANSL1	116	Q7Z3B3
DGLRPDARYVVQVRA	EPHB3	511	P54753
GVERLRNPDLIQAGY	NLRP2	541	Q9NX02
VAFLPRQAGLRERAA	EPHA10	396	Q5JZY3
LYVDPQGRRARAQEL	CDC42BPB	1446	Q9Y5S2
VLVGDRNDNAPRVLY	PCDHGB5	546	Q9Y5G0
RIQRRGPCIIYNEDN	RPL4	201	P36578
LLRDAIRRQGAYNID	HK3	201	P52790
EAGNPQARPLRVYFR	HELZ	716	P42694
ARFRPDQRFLEEGNL	OSBPL6	851	Q9BZF3
LSYDGRLVINRVPRA	EIPR1	366	Q53HC9
PDAAAYLARLQQTRR	NDOR1	576	Q9UHB4
QRLEQVLPRDERGAY	IFT172	1656	Q9UG01
LVVRNLRPQDSGRYS	OBSCN	3241	Q5VST9
VRDDQRQYLPGEVLR	NKX3-2	286	P78367
ARGNLGVYQETRERL	CD2BP2	211	O95400
RDLQPDQARRPDYAV	FZD8	571	Q9H461
RRDLVAQGPRYVVQI	DYNC2H1	3341	Q8NCM8
GEERRRVNQFLDYLQ	IL5	106	P05113
EEQRYQAFREAPGRL	GRID2IP	946	A4D2P6
YEVRAGPAGELRLRQ	LACTBL1	396	A8MY62
LPARSEQARRQSGLY	FNBP1	486	Q96RU3
YERIDGRVRGNLRQA	CHD6	826	Q8TD26
GDVLNYIFRNRELRP	COL19A1	151	Q14993
LPGDVDRARQYVLQS	PDSS1	356	Q5T2R2
GRLRVYQSGPRAVVE	FCGBP	566	Q9Y6R7
YRIRIQAINEIGAGP	FNDC3B	931	Q53EP0
DLPEENQAREGYRAI	C5	441	P01031
EYQAGPGRLRLRLVS	C2CD4D	226	B7Z1M9
RRPDLRYQLGFSVQN	APBA1	751	Q02410
RLQEFLRFQDPGRIV	CEMIP2	296	Q9UHN6
RAALERYVPRLQGAL	CYP26C1	151	Q6V0L0
AYRGREVVENNLPLR	BCL6	156	P41182
GEQLRERRSVAYNGP	MARK1	616	Q9P0L2
PERLPYQEAVQRDFR	MAN2C1	51	Q9NTJ4
DRVPYGISAIERNAR	FAM110B	336	Q8TC76
LRGRNEEQGIPLEYL	DCK	191	P27707
RGYAVQRLPELLTER	DCAF12L1	76	Q5VU92
SQLVRYREVQLPDRG	IDE	761	P14735
QTRELRVLYGPRLDE	ICAM1	386	P05362
PDAANRPVRYAIDRE	CDH22	421	Q9UJ99
LYAVNRRLRALEEQG	FATE1	141	Q969F0
ENLDLPYGLERAIQR	FKBP4	196	Q02790
EQQPIGRRLFRDFLA	GRK7	61	Q8WTQ7
YQRRSLRGAQLTPEE	HPS6	411	Q86YV9
QRERAALPIAQYGNR	DHX34	156	Q14147
SAQLRPLLGDRQYIR	RUBCN	136	Q92622
RQYDGLGELLRALPR	RYR1	2126	P21817
AQRFYNLVLLPRVRD	BYSL	246	Q13895
VLRRSAGRAPYQEND	JADE3	751	Q92613
NPGQRVRYRVFALDQ	C4A	151	P0C0L4
GIVDAYRQALPQVRL	CPNE1	371	Q99829
RPAADILRRNPQQDY	MAP4K5	6	Q9Y4K4
NFRRRAVAQGAPREI	MICAL2	1326	O94851
LRPDQRYLEEGNIQA	OSBPL7	761	Q9BZF2
QTPQRLLEVRGRLYE	RFC3	266	P40938
ARRVRPDGSVQYLVE	PHF1	546	O43189
HVLRQYLDPAQRGVR	METTL26	16	Q96S19
QGLAAARRRRSDPYV	SYTL1	291	Q8IYJ3
SRYNLVRGQGPERLV	NLE1	331	Q9NVX2
EARLYILQQARRDPL	UTRN	2356	P46939
AVRNYNRDEVQLPRG	SPDYA	206	Q5MJ70
PDENIRANLRQYGLE	TRMT11	266	Q7Z4G4
QGLYDAVRLRERPVS	SLC18A3	491	Q16572
VRDLENLGERALPYR	MRPS6	36	P82932
RRIYDETQGRQQVLP	SMCHD1	1761	A6NHR9
PGQRVYVVAERDGDR	SHH	311	Q15465
YPGREAQARRAQEEA	VGF	576	O15240
TRAYNRPTLRLELQG	F5	2046	P12259
NPPEGFNLRRDVYIR	POFUT2	51	Q9Y2G5
TEERVQPEYQRRRGA	RGP1	261	Q92546
EVALVNAYPEQRRAR	SSMEM1	116	Q8WWF3
RGYEDRDRADPQQLP	PRDM15	361	P57071
EIRDRYGGLRSNPVI	PSG9	311	Q00887
QYAEDLIRRQAERRG	HDHD5	286	Q9BXW7
YQDAAGPREAFRQLR	SCAND1	116	P57086
YADLEAVNRARRPLA	RHOBTB2	146	Q9BYZ6
QSDPRGVRYALVLQD	SORCS2	416	Q96PQ0
RYRQDPQLGRTLASL	SIL1	411	Q9H173
AYAEAELGQGRQPLR	MTG2	391	Q9H4K7
DRPNLYLEVRRKTGN	WRN	731	Q14191
YADLEAVNRARRPLA	RHOBTB1	146	O94844
GLYNVDPTIRERELR	RERE	1291	Q9P2R6
AAAAGRIPTNYLRRE	PNPT1	106	Q8TCS8
YLGPQCEQVDRNIRR	HHIP	661	Q96QV1
PNYRRLETQREINGA	SNAI3	16	Q3KNW1
RAVEPALLQRYRAQT	CHPF	721	Q8IZ52
LRLRYEDLVRQPRAQ	CHST7	371	Q9NS84
EPGVREAVLNAYRQL	NCAPD2	686	Q15021
YSNREVIRELQGRPD	C15orf62	46	A8K5M9
DIYRVVVEGERGNRP	TNRC18	2186	O15417
INRRDLDPNAGRFVR	UNC119	116	Q13432
LQDPFNRAAGERYRR	MIPEP	651	Q99797
ANLPLRFGRNVQEER	NPVF	86	Q9HCQ7
YQRLVRAEQGLPIRS	PIK3R5	141	Q8WYR1
RYLDPGDRDVADRIQ	ROM1	186	Q03395
RLYLNGNRIERLSPE	SLITRK5	461	O94991
APEVRDQGYLRLLQT	TRAPPC14	181	Q8WVR3
RISVFRPGLRDVAYQ	SSBP1	86	Q04837
LDLQVRRVRPGEYRQ	RLIM	321	Q9NVW2
RLQELVRRGNSQYPG	POLR2A	401	P24928
LFYRQRPREGPEAEL	USP35	921	Q9P2H5
LRRHRPLQEVYPEAN	TYR	401	P14679
RYRQIGPLIDRQIFR	TENM4	2056	Q6N022
DEALGLPLAQLRRYR	PPP1R3F	41	Q6ZSY5
QEQLRYEQERRPGRR	SAFB2	716	Q14151
VARREQPESLRAQYG	NME9	256	Q86XW9
RRFRYQEAAGPREAL	ZNF496	46	Q96IT1
RYAEAVQLLGRELQR	TTC30A	26	Q86WT1
QREGLPEDGTLYRIN	GTF3C2	361	Q8WUA4
PYGSDRLVQLAARLR	ZBTB32	11	Q9Y2Y4
PNEEADYLGVRIQLR	PIEZO1	2376	Q92508
IVFEDNPGRLNERRF	ZNF202	356	O95125
RFPRANEFLEELRQG	PRRG3	16	Q9BZD7
PYSVLDDEGRNLRQQ	TUB	11	P50607
NPLYEERRNLDRQAG	ZNF318	1171	Q5VUA4
ENRNDLVGRDVVAPY	TRPM7	211	Q96QT4
AQFVREITRPNGERY	ZMYM3	1116	Q14202
VERYVAGFPDLQRRL	EXD3	186	Q8N9H8
RRGQSIRYLVPDLVQ	NMNAT1	231	Q9HAN9