Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionneuropeptide Y receptor activity

QRFPR NPY4R2 NPY4R

2.67e-05111113GO:0004983
GeneOntologyMolecularFunctionimmunoglobulin receptor activity

CD200R1 FCGR3A FCGR3B

5.82e-05141113GO:0019763
GeneOntologyMolecularFunctionglycosylated region protein binding

CD200R1 CLEC4G

9.15e-0531112GO:0140081
GeneOntologyMolecularFunctionpancreatic polypeptide receptor activity

NPY4R2 NPY4R

1.82e-0441112GO:0001602
GeneOntologyMolecularFunctionlow-affinity IgG receptor activity

FCGR3A FCGR3B

1.82e-0441112GO:0019772
GeneOntologyMolecularFunctionIgE receptor activity

FCGR3A FCGR3B

4.53e-0461112GO:0019767
GeneOntologyMolecularFunctionIgE binding

FCGR3A FCGR3B

6.32e-0471112GO:0019863
GeneOntologyMolecularFunctionIgG receptor activity

FCGR3A FCGR3B

6.32e-0471112GO:0019770
GeneOntologyMolecularFunctioninterleukin-17 receptor activity

IL17RE IL17RA

8.39e-0481112GO:0030368
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

PLXNA3 ERBB2 NTRK2 PTH2R CD200R1 MST1R QRFPR NPY4R2 P2RX5 NPY4R FCGR3A FCGR3B IL17RE UNC5C IL17RA FZD2 EDA2R

1.27e-03135311117GO:0004888
GeneOntologyMolecularFunctionguanylate kinase activity

MAGI3 CARD11

1.63e-03111112GO:0004385
GeneOntologyMolecularFunctionIgG binding

FCGR3A FCGR3B

1.63e-03111112GO:0019864
GeneOntologyMolecularFunctionphosphatidylinositol binding

RAG2 BCAS3 ZCCHC2 PLA2G4E FCGR3A FCGR3B SNX18

1.94e-033161117GO:0035091
GeneOntologyBiologicalProcessperforin production

FCGR3A FCGR3B

2.72e-0521082GO:0035944
GeneOntologyBiologicalProcessnegative regulation of T cell differentiation in thymus

RAG2 ERBB2 CLEC4G

3.84e-05131083GO:0033085
GeneOntologyCellularComponentFc-gamma receptor III complex

FCGR3A FCGR3B

1.55e-0441072GO:0033001
MousePhenoabnormal skin physiology

RAG2 RIPK4 PLA2G4E F5 GADD45A ABHD5 IL17RE CARD11 IL17RA WDR1 NIN

1.02e-062888311MP:0005501
Domain-

PLXNA3 SELENBP1 MED16 NBEAL1 BCAS3 MST1R CDC40 DCAF10 NLE1 CORO6 IFT80 WDR1 CDC20 WDR17 FBXW7

8.37e-10333108152.130.10.10
DomainWD40/YVTN_repeat-like_dom

PLXNA3 SELENBP1 MED16 NBEAL1 BCAS3 MST1R CDC40 DCAF10 NLE1 CORO6 IFT80 WDR1 CDC20 WDR17 FBXW7

9.09e-1033510815IPR015943
DomainWD40

MED16 NBEAL1 BCAS3 CDC40 DCAF10 NLE1 CORO6 IFT80 WDR1 CDC20 WDR17 FBXW7

3.36e-0825910812PF00400
DomainWD40

MED16 NBEAL1 BCAS3 CDC40 DCAF10 NLE1 CORO6 IFT80 WDR1 CDC20 WDR17 FBXW7

4.90e-0826810812SM00320
DomainWD40_repeat

MED16 NBEAL1 BCAS3 CDC40 DCAF10 NLE1 CORO6 IFT80 WDR1 CDC20 WDR17 FBXW7

5.76e-0827210812IPR001680
DomainWD_REPEATS_1

MED16 NBEAL1 BCAS3 CDC40 DCAF10 NLE1 CORO6 IFT80 WDR1 CDC20 WDR17 FBXW7

7.31e-0827810812PS00678
DomainWD_REPEATS_2

MED16 NBEAL1 BCAS3 CDC40 DCAF10 NLE1 CORO6 IFT80 WDR1 CDC20 WDR17 FBXW7

7.60e-0827910812PS50082
DomainWD_REPEATS_REGION

MED16 NBEAL1 BCAS3 CDC40 DCAF10 NLE1 CORO6 IFT80 WDR1 CDC20 WDR17 FBXW7

7.60e-0827910812PS50294
DomainWD40_repeat_dom

MED16 NBEAL1 BCAS3 CDC40 DCAF10 NLE1 CORO6 IFT80 WDR1 CDC20 WDR17 FBXW7

1.50e-0729710812IPR017986
DomainWD40_repeat_CS

CDC40 DCAF10 NLE1 CORO6 WDR1 CDC20 WDR17 FBXW7

4.98e-061641088IPR019775
DomainNPY_rcpt

QRFPR NPY4R2 NPY4R

1.54e-0591083IPR000611
DomainNPY4_rcpt

NPY4R2 NPY4R

3.31e-0521082IPR001933
DomainN2O_reductase_N

WDR1 CDC20 WDR17

8.13e-05151083IPR011045
DomainApc4_WD40_dom

CORO6 CDC20 WDR17

2.00e-04201083IPR024977
DomainANAPC4_WD40

CORO6 CDC20 WDR17

2.00e-04201083PF12894
DomainTSP_1

ADAMTSL1 PAPLN ISM2 UNC5C

4.84e-04631084PF00090
DomainSEFIR

IL17RE IL17RA

4.89e-0461082PF08357
DomainSEFIR_dom

IL17RE IL17RA

4.89e-0461082IPR013568
DomainSEFIR

IL17RE IL17RA

4.89e-0461082PS51534
DomainIPT

PLXNA3 PKHD1L1 MST1R

4.97e-04271083SM00429
DomainTSP1

ADAMTSL1 PAPLN ISM2 UNC5C

5.46e-04651084SM00209
DomainTSP1_rpt

ADAMTSL1 PAPLN ISM2 UNC5C

5.46e-04651084IPR000884
DomainTSP1

ADAMTSL1 PAPLN ISM2 UNC5C

5.46e-04651084PS50092
DomainTIG

PLXNA3 PKHD1L1 MST1R

7.51e-04311083PF01833
DomainIg-like_fold

SLAMF8 PLXNA3 ADAMTSL1 NTRK2 PAPLN PKHD1L1 CD200R1 MST1R FCGR3A FCGR3B UNC5C HCFC2

7.83e-0470610812IPR013783
DomainIPT

PLXNA3 PKHD1L1 MST1R

8.25e-04321083IPR002909
DomainG-protein_beta_WD-40_rep

NLE1 WDR1 WDR17 FBXW7

1.49e-03851084IPR020472
Domain-

PLXNA3 ADAMTSL1 NTRK2 PAPLN PKHD1L1 CD200R1 MST1R FCGR3A FCGR3B UNC5C HCFC2

1.58e-03663108112.60.40.10
DomainDUF4599

SPATA31D4 SPATA31D3

2.11e-03121082PF15371
DomainDUF4599

SPATA31D4 SPATA31D3

2.11e-03121082IPR027970
DomainPLAC

ADAMTSL1 PAPLN

2.88e-03141082PF08686
DomainSushi

CD46 C4BPA CSMD1

3.38e-03521083PF00084
DomainCCP

CD46 C4BPA CSMD1

3.76e-03541083SM00032
DomainSUSHI

CD46 C4BPA CSMD1

4.17e-03561083PS50923
DomainSushi_SCR_CCP_dom

CD46 C4BPA CSMD1

4.39e-03571083IPR000436
DomainFurin_repeat

ERBB2 FRAS1

4.77e-03181082IPR006212
DomainFU

ERBB2 FRAS1

4.77e-03181082SM00261
DomainPLAC

ADAMTSL1 PAPLN

5.31e-03191082PS50900
DomainPLAC

ADAMTSL1 PAPLN

5.31e-03191082IPR010909
Pubmed

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner.

RAG2 IL17RE IL17RA

6.63e-076113321993848
Pubmed

Functional genetic analysis of mouse chromosome 11.

ERBB2 NLE1 WDR1 MED13

8.92e-0723113412955145
Pubmed

Suppression of Metastases Using a New Lymphocyte Checkpoint Target for Cancer Immunotherapy.

RAG2 FCGR3A FCGR3B

9.33e-0613113326787820
Pubmed

Human Fc gamma RIII: cloning, expression, and identification of the chromosomal locus of two Fc receptors for IgG.

FCGR3A FCGR3B

1.05e-05211322521732
Pubmed

PP1 promotes cyclin B destruction and the metaphase-anaphase transition by dephosphorylating CDC20.

PPA1 CDC20

1.05e-052113232755477
Pubmed

Single-cell analyses identify dysfunctional CD16+ CD8 T cells in smokers.

FCGR3A FCGR3B

1.05e-052113233163982
Pubmed

Association study of copy number variants in FCGR3A and FCGR3B gene with risk of ankylosing spondylitis in a Chinese population.

FCGR3A FCGR3B

1.05e-052113226494566
Pubmed

Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.

FCGR3A FCGR3B

1.05e-052113223917248
Pubmed

Evidence for gene recombination in FCGR3 gene variants.

FCGR3A FCGR3B

1.05e-052113219320901
Pubmed

Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes.

FCGR3A FCGR3B

1.05e-052113225966632
Pubmed

The Fc gamma receptor of natural killer cells is a phospholipid-linked membrane protein.

FCGR3A FCGR3B

1.05e-05211322967436
Pubmed

Binding of protein S to factor Va associated with inhibition of prothrombinase that is independent of activated protein C.

F5 PROS1

1.05e-05211328428962
Pubmed

Strength and corticosteroid responsiveness of mdx mice is unchanged by RAG2 gene knockout.

RAG2 DMD

1.05e-052113217452104
Pubmed

Identification and functional characterization of a novel interleukin 17 receptor: a possible mitogenic activation through ras/mitogen-activated protein kinase signaling pathway.

IL17RE IL17RA

1.05e-052113216310341
Pubmed

Exacerbated venous thromboembolism in mice carrying a protein S K196E mutation.

F5 PROS1

1.05e-052113226251307
Pubmed

Plasma protein S residues 37-50 mediate its binding to factor Va and inhibition of blood coagulation.

F5 PROS1

1.05e-052113223892573
Pubmed

Somatic mutations of the CDC4 (FBXW7) gene in hereditary colorectal tumors.

CDC40 FBXW7

1.05e-052113219420964
Pubmed

Charge variant analysis of proposed biosimilar to Trastuzumab.

ERBB2 FCGR3A

1.05e-052113228087106
Pubmed

Cloning and sequencing of a cDNA encoding the murine vitamin K-dependent protein S.

C4BPA PROS1

1.05e-05211328148380
Pubmed

Low copy numbers of FCGR3A and FCGR3B associated with Chinese patients with SLE and AASV.

FCGR3A FCGR3B

1.05e-052113228355982
Pubmed

The human low affinity immunoglobulin G Fc receptor III-A and III-B genes. Molecular characterization of the promoter regions.

FCGR3A FCGR3B

1.05e-05211327836402
Pubmed

Identification of an ADAM17 cleavage region in human CD16 (FcγRIII) and the engineering of a non-cleavable version of the receptor in NK cells.

FCGR3A FCGR3B

1.05e-052113225816339
Pubmed

Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia.

RAG2 WDR1

1.05e-052113217515402
Pubmed

The loss of the CD16 B73.1/Leu11c epitope occurring in some primary immunodeficiency diseases is not associated with the FcgammaRIIIa-48L/R/H polymorphism.

FCGR3A FCGR3B

1.05e-052113220664961
Pubmed

FCGR Genetic Variation in Two Populations From Ecuador Highlands-Extensive Copy-Number Variation, Distinctive Distribution of Functional Polymorphisms, and a Novel, Locally Common, Chimeric FCGR3B/A (CD16B/A) Gene.

FCGR3A FCGR3B

1.05e-052113234108956
Pubmed

The roles of factor Va and protein S in formation of the activated protein C/protein S/factor Va inactivation complex.

F5 PROS1

1.05e-052113231364267
Pubmed

The human natural killer cytotoxic cell line NK-92, once armed with a murine CD16 receptor, represents a convenient cellular tool for the screening of mouse mAbs according to their ADCC potential.

FCGR3A FCGR3B

1.05e-052113223770975
Pubmed

In vivo clearance of human protein S in a mouse model: influence of C4b-binding protein and the Heerlen polymorphism.

C4BPA PROS1

1.05e-052113216100035
Pubmed

Confirmation of association of FCGR3B but not FCGR3A copy number with susceptibility to autoantibody positive rheumatoid arthritis.

FCGR3A FCGR3B

1.05e-052113222290871
Pubmed

Fcγ receptor IIIb polymorphism and use of glucocorticoids at baseline are associated with infusion reactions to infliximab in patients with rheumatoid arthritis.

FCGR3A FCGR3B

1.05e-052113220980704
Pubmed

Nucleotide sequence of a new Fc gamma receptor IIIB allele that codes for a neutrophil antigen.

FCGR3A FCGR3B

1.05e-052113211034564
Pubmed

C-terminal residues 621-635 of protein S are essential for binding to factor Va.

F5 PROS1

1.05e-052113210593904
Pubmed

Immunoglobulin G fragment C receptor polymorphisms and efficacy of preoperative chemotherapy plus trastuzumab and lapatinib in HER2-positive breast cancer.

ERBB2 FCGR3A

1.05e-052113227378608
Pubmed

Cooperation of neurotrophin receptor TrkB and Her2 in breast cancer cells facilitates brain metastases.

ERBB2 NTRK2

1.05e-052113228446206
Pubmed

MYBL2 in synergy with CDC20 promotes the proliferation and inhibits apoptosis of gastric cancer cells.

CDC20 MYBL2

1.05e-052113234358419
Pubmed

Separate promoters from proximal and medial control regions contribute to the natural killer cell-specific transcription of the human FcgammaRIII-A (CD16-A) receptor gene.

FCGR3A FCGR3B

1.05e-05211328940055
Pubmed

Protein S and C4b-binding protein: components involved in the regulation of the protein C anticoagulant system.

C4BPA PROS1

1.05e-05211321833851
Pubmed

FCGR3A and FCGR3B copy number variations are risk factors for sarcoidosis.

FCGR3A FCGR3B

1.05e-052113227059607
Pubmed

Association of FCGR3A and FCGR3B copy number variations with systemic lupus erythematosus and rheumatoid arthritis in Taiwanese patients.

FCGR3A FCGR3B

1.05e-052113225154742
Pubmed

A human immunoglobulin G receptor exists in both polypeptide-anchored and phosphatidylinositol-glycan-anchored forms.

FCGR3A FCGR3B

1.05e-05211322525780
Pubmed

FcgammaRIII expression on cultured human keratinocytes and upregulation by interferon-gamma.

FCGR3A FCGR3B

1.05e-052113212445195
Pubmed

Alternative membrane forms of Fc gamma RIII(CD16) on human natural killer cells and neutrophils. Cell type-specific expression of two genes that differ in single nucleotide substitutions.

FCGR3A FCGR3B

1.05e-05211322526846
Pubmed

B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions.

FCGR3A FCGR3B

1.05e-052113218292508
Pubmed

In vitro and in vivo antitumor effect of a trivalent bispecific antibody targeting ErbB2 and CD16.

ERBB2 FCGR3A

1.05e-052113218787406
Pubmed

hLodestar/HuF2 interacts with CDC5L and is involved in pre-mRNA splicing.

TTF2 MATR3 MYBL2

1.48e-0515113312927788
Pubmed

Fc gamma receptor genes as risk markers for localized aggressive periodontitis in African-Americans.

FCGR3A FCGR3B

3.13e-053113212027254
Pubmed

Novel APC-cleavage sites in FVa provide insights into mechanisms of action of APC and its cofactor protein S.

F5 PROS1

3.13e-053113219874463
Pubmed

Analysis of Fc gamma RIII (CD16) membrane expression and association with CD3 zeta and Fc epsilon RI-gamma by site-directed mutation.

FCGR3A FCGR3B

3.13e-05311321825220
Pubmed

Polymorphism of Fc gamma RIIa may affect the efficacy of gamma-globulin therapy in Kawasaki disease.

FCGR3A FCGR3B

3.13e-053113216133986
Pubmed

Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya.

FCGR3A FCGR3B

3.13e-053113228427365
Pubmed

Different stabilities of the structurally related receptors for IgE and IgG on the cell surface are determined by length of the stalk region in their alpha-chains.

FCGR3A FCGR3B

3.13e-053113216709862
Pubmed

Patterns of low-affinity immunoglobulin receptor polymorphisms in stroke and homozygous sickle cell disease.

FCGR3A FCGR3B

3.13e-053113211835346
Pubmed

FcgammaRIIa, IIIa and IIIb gene polymorphisms in Behçet's disease: do they have any clinical implications?

FCGR3A FCGR3B

3.13e-053113219026120
Pubmed

Immunoglobulin G fc-receptor (FcgammaR) IIA, IIIA, and IIIB polymorphisms related to disease severity in rheumatoid arthritis.

FCGR3A FCGR3B

3.13e-053113212064825
Pubmed

FcgammaRIIA, FcgammaRIIIA and FcgammaRIIIB polymorphisms in Spanish patients with systemic lupus erythematosus.

FCGR3A FCGR3B

3.13e-053113212121275
Pubmed

Infectious complications after chemotherapy and stem cell transplantation in multiple myeloma: implications of Fc gamma receptor and myeloperoxidase promoter polymorphisms.

FCGR3A FCGR3B

3.13e-053113218452102
Pubmed

Fcgamma receptor polymorphisms in relation to periodontitis.

FCGR3A FCGR3B

3.13e-053113212834496
Pubmed

Smad4-dependent TGF-beta signaling suppresses RON receptor tyrosine kinase-dependent motility and invasion of pancreatic cancer cells.

MST1R SMAD4

3.13e-053113218310076
Pubmed

Fc gamma RIIa, IIIa and IIIb polymorphisms in Turkish children susceptible to recurrent infectious diseases.

FCGR3A FCGR3B

3.13e-053113216550341
Pubmed

Association of the Fc gamma receptor IIA-R/R131 genotype with myasthenia gravis in Dutch patients.

FCGR3A FCGR3B

3.13e-053113214597109
Pubmed

Genetic polymorphism of Fcγ-receptors IIa, IIIa and IIIb in South Indian patients with generalized aggressive periodontitis.

FCGR3A FCGR3B

3.13e-053113222167032
Pubmed

Polymorphisms of Immunoglobulin G Fc Receptors in Pediatric Guillain-Barré Syndrome.

FCGR3A FCGR3B

3.13e-053113227064330
Pubmed

Significant differences in FcγRIIa, FcγRIIIa and FcγRIIIb genes polymorphism and anti-malarial IgG subclass pattern are associated with severe Plasmodium falciparum malaria in Saudi children.

FCGR3A FCGR3B

3.13e-053113234551786
Pubmed

FCGR2A, FCGR3A, FCGR3B polymorphisms and susceptibility to rheumatoid arthritis: a meta-analysis.

FCGR3A FCGR3B

3.13e-053113226314337
Pubmed

Copy number variation of FCGR3A rather than FCGR3B and FCGR2B is associated with susceptibility to anti-GBM disease.

FCGR3A FCGR3B

3.13e-053113219946017
Pubmed

Fcgamma receptor IIa, IIIa, and IIIb polymorphisms in German patients with systemic lupus erythematosus: association with clinical symptoms.

FCGR3A FCGR3B

3.13e-053113212176802
Pubmed

No association of Fc gamma RIIa, Fc gamma RIIIa and Fc gamma RIIIb polymorphisms with MS.

FCGR3A FCGR3B

3.13e-053113212864991
Pubmed

Cloning and functional expression of cDNAs encoding human and rat pancreatic polypeptide receptors.

NPY4R2 NPY4R

3.13e-05311328643460
Pubmed

Genetic Variants That Are Associated with Neuropsychiatric Systemic Lupus Erythematosus.

FCGR3A FCGR3B

3.13e-053113226773105
Pubmed

A novel functional assay of protein C in human plasma and its comparison with amidolytic and anticoagulant assays.

F5 PROS1

3.13e-05311321615482
Pubmed

Sertoli Cells Improve Myogenic Differentiation, Reduce Fibrogenic Markers, and Induce Utrophin Expression in Human DMD Myoblasts.

ERBB2 DMD

3.13e-053113234680138
Pubmed

Association of Fcgamma receptor IIa genotype with chronic periodontitis in Caucasians.

FCGR3A FCGR3B

3.13e-053113215152814
Pubmed

Catchup: a mouse model for imaging-based tracking and modulation of neutrophil granulocytes.

FCGR3A FCGR3B

3.13e-053113225775045
Pubmed

The Fc gamma receptor genotype as a severity factor for chronic periodontitis in Japanese patients.

FCGR3A FCGR3B

3.13e-053113211699473
Pubmed

Associations between FCGR3A polymorphisms and susceptibility to rheumatoid arthritis: a metaanalysis.

FCGR3A FCGR3B

3.13e-053113218843786
Pubmed

Absence of association between the Fc gamma receptor IIIA-176F/V polymorphism and the severity of malaria in Thai.

FCGR3A FCGR3B

3.13e-053113212501257
Pubmed

Polymorphisms of Fc gamma-receptors RIIa, RIIIa, and RIIIb in patients with adult periodontal diseases.

FCGR3A FCGR3B

3.13e-053113211528518
Pubmed

Fcgamma receptor IIIA polymorphism as a risk-factor for coronary artery disease.

FCGR3A FCGR3B

3.13e-053113215910853
Pubmed

Role of activating FcγR gene polymorphisms in Kawasaki disease susceptibility and intravenous immunoglobulin response.

FCGR3A FCGR3B

3.13e-053113222565545
Pubmed

Associations between FCGR2A rs1801274, FCGR3A rs396991, FCGR3B NA1/NA2 polymorphisms and periodontitis: a meta-analysis.

FCGR3A FCGR3B

3.13e-053113223649770
Pubmed

Analysis of in vitro ADCC and clinical response to trastuzumab: possible relevance of FcγRIIIA/FcγRIIA gene polymorphisms and HER-2 expression levels on breast cancer cell lines.

ERBB2 FCGR3A

3.13e-053113226450443
Pubmed

Fcgamma receptor polymorphisms and their association with periodontal disease: a meta-analysis.

FCGR3A FCGR3B

3.13e-053113220149216
Pubmed

Risk of periodontitis in systemic lupus erythematosus is associated with Fcgamma receptor polymorphisms.

FCGR3A FCGR3B

3.13e-053113212710759
Pubmed

Cutting edge: intravenous Ig inhibits invariant NKT cell-mediated allergic airway inflammation through FcγRIIIA-dependent mechanisms.

FCGR3A FCGR3B

3.13e-053113221317388
Pubmed

Allelic and copy-number variations of FcγRs affect granulocyte function and susceptibility for autoimmune blistering diseases.

FCGR3A FCGR3B

3.13e-053113226032265
Pubmed

Association study of copy number variants in CCL3L1, FCGR3A and FCGR3B genes with risk of ankylosing spondylitis in a West Algerian population.

FCGR3A FCGR3B

3.13e-053113231433132
Pubmed

Drug-induced agranulocytosis: impact of different fcgamma receptor polymorphisms?

FCGR3A FCGR3B

3.13e-053113216160618
Pubmed

Susceptibility to Plasmodium falciparum Malaria: Influence of Combined Polymorphisms of IgG3 Gm Allotypes and Fc Gamma Receptors IIA, IIIA, and IIIB.

FCGR3A FCGR3B

3.13e-053113233424858
Pubmed

FcgammaRIIA and FcgammaRIIIB mediate nuclear factor activation through separate signaling pathways in human neutrophils.

FCGR3A FCGR3B

3.13e-053113219342628
Pubmed

The role of fcgamma receptor gene polymorphism in pediatric renal transplant rejections.

FCGR3A FCGR3B

3.13e-053113219100392
Pubmed

HIV-1 Tat inhibits human natural killer cell function by blocking L-type calcium channels.

FCGR3A FCGR3B

3.13e-05311329743356
Pubmed

Study of common functional genetic polymorphisms of FCGR2A, 3A and 3B genes and the risk for cryptococcosis in HIV-uninfected patients.

FCGR3A FCGR3B

3.13e-053113217710620
Pubmed

Association of rheumatoid factor production with FcgammaRIIIa polymorphism in Taiwanese rheumatoid arthritis.

FCGR3A FCGR3B

3.13e-053113216542359
Pubmed

IL-17 Receptor Signaling in the Lung Epithelium Is Required for Mucosal Chemokine Gradients and Pulmonary Host Defense against K. pneumoniae.

IL17RE IL17RA

3.13e-053113227923703
Pubmed

SMAD4 Loss Induces c-MYC-Mediated NLE1 Upregulation to Support Protein Biosynthesis, Colorectal Cancer Growth, and Metastasis.

NLE1 SMAD4

3.13e-053113236219392
Pubmed

Role of IL-17A and neutrophils in fibrosis in experimental hypersensitivity pneumonitis.

RAG2 IL17RA

3.13e-053113223453796
Pubmed

Severity of Guillain-Barré syndrome is associated with Fc gamma Receptor III polymorphisms.

FCGR3A FCGR3B

3.13e-053113215833371
Pubmed

Correlation of HER2, FCGR2A, and FCGR3A gene polymorphisms with trastuzumab related cardiac toxicity and efficacy in a subgroup of patients from UNICANCER-PACS 04 trial.

ERBB2 FCGR3A

3.13e-053113223780683
Pubmed

Fcgamma receptor IIIA polymorphism as a risk factor for acute poliomyelitis.

FCGR3A FCGR3B

3.13e-053113212447772
Pubmed

BARD1 regulates BRCA1-mediated transactivation of the p21WAF1/CIP1 and Gadd45 promoters.

BARD1 GADD45A

3.13e-053113218243530
Cytoband1q23

F5 FCGR3A FCGR3B

2.48e-052311331q23
GeneFamilyWD repeat domain containing

MED16 NBEAL1 BCAS3 CDC40 DCAF10 NLE1 CORO6 IFT80 WDR1 CDC20 WDR17 FBXW7

1.68e-092628012362
GeneFamilyADAMTS like

ADAMTSL1 PAPLN

4.00e-047802947
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

ERBB2 P2RX5 PRCP

1.49e-0351803870
GeneFamilyADAM metallopeptidase domain containing|CD molecules

SLAMF8 ERBB2 CD46 MST1R FCGR3A FCGR3B IL17RA

1.79e-03394807471
GeneFamilyIntegrator complex

INTS3 INTS5

1.96e-03158021366
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CD46 C4BPA CSMD1

2.06e-03578031179
ToppCellControl-Control-Lymphocyte-T/NK-NK_activated|Control / Disease, condition lineage and cell class

ERBB2 ZNF772 ZCCHC2 NT5M FCGR3A FCGR3B MACF1 CARD11

4.21e-08198113876d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

ERBB2 FRAS1 SELENBP1 NBEAL1 MAGI3 IL17RE IFT80

7.49e-07198113785f424cd9bb3117c9e322031024aabb87696ce47
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ERBB2 FRAS1 NBEAL1 LMNTD2 MAGI3 IL17RE IFT80

7.74e-071991137d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ERBB2 FRAS1 SELENBP1 NBEAL1 MAGI3 IL17RE IFT80

8.01e-072001137ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellcontrol-HLA-DR-_S100A+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RNF130 TMEM144 ROGDI F5 GASK1B IL17RA FZD2

8.01e-072001137107a0665fb20247511a430178effd7630a619488
ToppCellBAL-Severe-cDC_4|Severe / Compartment, Disease Groups and Clusters

SELENBP1 PARP8 F5 NT5M CORO6 CSMD1

3.16e-06158113673f66689ef59f71b14cb7141ca5951cc47fe57c1
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Basal_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

RIPK4 CLEC4G KIAA1958 FBXO32 CDC20 ANAPC7

4.82e-061701136aabe993c9f337b1caaeb0e64626a3920579c41b7
ToppCelldroplet-Lung-nan-21m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLAMF8 RNF130 F5 FCGR3B PRCP IL17RA

5.33e-0617311369019049b1e2a24cb0bbbc620d64ef29dd18cc4c6
ToppCelldroplet-Lung-nan-21m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLAMF8 RNF130 F5 FCGR3B PRCP IL17RA

5.33e-061731136077029eecfe636a5baf5f70464e1713b3f6b4274
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLAMF8 TTF2 BARD1 CD200R1 CDC20 MYBL2

5.51e-0617411367b318796728001c17b4043d2b033330c7be40c78
ToppCellPBMC-Mild-cDC_11|Mild / Compartment, Disease Groups and Clusters

SLAMF8 STK17A PPM1J GCSAM ZC3HAV1L DMD

6.07e-061771136974305e4c0eff90134c4e58cf11b955d1eee0501
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FRAS1 PAPLN PKHD1L1 MST1R NPY4R IL17RE

6.90e-061811136330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FRAS1 PAPLN PKHD1L1 MST1R NPY4R IL17RE

6.90e-0618111363f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RNF130 FRAS1 STK17A SHC4 DMD FBXW7

7.12e-061821136ecb5624c9074cc6449fad961df54c926c2681d54
ToppCellsevere-Myeloid-Neutrophils_3|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CD46 F5 ABHD5 FCGR3B C4BPA IL17RA

9.95e-061931136f4d43dfbf4115dd0f843ea5cf08049220342a047
ToppCellsevere-Myeloid-Neutrophils_3|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CD46 F5 ABHD5 FCGR3B C4BPA IL17RA

1.02e-0519411361f8edab1c8ba48bc0114429ea47aab378b5830b7
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADAMTSL1 NTRK2 F5 FCGR3B IL17RA CSMD1

1.06e-051951136d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ADAMTSL1 NTRK2 F5 FCGR3B IL17RA CSMD1

1.06e-05195113619853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellhealthy_donor-Lymphocytic-ILC-NK_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

ERBB2 PARP8 FCGR3A FCGR3B MACF1 CARD11

1.15e-051981136d7053a898e04478c577381085f615edaad3cdc5b
ToppCellhealthy_donor-Lymphocytic-ILC|healthy_donor / Disease condition, Lineage, Cell class and subclass

ERBB2 PARP8 FCGR3A FCGR3B MACF1 CARD11

1.15e-051981136aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCellCOVID_non-vent-Lymphocytic-ILC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ERBB2 PARP8 FCGR3A FCGR3B MACF1 CARD11

1.18e-051991136df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCellcontrol-cDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLAMF8 RNF130 ROGDI CD200R1 PRCP FZD2

1.18e-05199113631825ba336603fe940dea6022e18ec25af110f4c
ToppCellTransverse-NK_cell|Transverse / Region, Cell class and subclass

CCNJL STK17A PARP8 FCGR3A FCGR3B ITGB1BP2

1.18e-0519911366d5d57addfed3947408b9af7d6aa78aaa3197f94
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ERBB2 FRAS1 SELENBP1 MAGI3 IL17RE IFT80

1.18e-0519911361c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCellTransverse-(0)_NK_cell-(00)_NK|Transverse / shred on region, Cell_type, and subtype

CCNJL STK17A PARP8 FCGR3A FCGR3B ITGB1BP2

1.18e-051991136b649375394bc55b8727814283defed711e899e9c
ToppCellCOVID_non-vent-Lymphocytic-ILC-NK_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ERBB2 PARP8 FCGR3A FCGR3B MACF1 CARD11

1.18e-051991136ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCellwk_08-11-Epithelial-Airway_epithelial_progenitor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FRAS1 ADAMTSL1 MAGI3 RIPK4 IL17RE DMD

1.18e-051991136af664e0d41a889a75dbf6cf0d50acd26f5ab3a3a
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERBB2 STK17A FCGR3A FCGR3B MACF1 CARD11

1.18e-051991136eb05ccae5187e4701bbbe6d714a6d2808fbcf306
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CCNJL ERBB2 STK17A FCGR3A FCGR3B MACF1

1.18e-05199113610c8729b779073c3bf808e85958d59147f0be5c5
ToppCellTransverse-NK_cell-NK|Transverse / Region, Cell class and subclass

CCNJL STK17A PARP8 FCGR3A FCGR3B ITGB1BP2

1.18e-051991136418e936d3528b6672ab54f77919588e4ed01a8d2
ToppCellTransverse-(0)_NK_cell|Transverse / shred on region, Cell_type, and subtype

CCNJL STK17A PARP8 FCGR3A FCGR3B ITGB1BP2

1.18e-0519911361970a85893b87eca18916df2504c5148fcd9ceb2
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ERBB2 FRAS1 LMNTD2 MAGI3 IL17RE IFT80

1.22e-0520011368683445ad5b70748c4a1f12eb77d47623085147e
ToppCellSepsis-Bac-SEP-Myeloid-cDC1|Bac-SEP / Disease, condition lineage and cell class

SLAMF8 PPA1 GCSAM CFAP20DC KIAA1958 DMD

1.22e-052001136cd381644fd8b8674a017d267bfbb00f2668294ae
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

ERBB2 PARP8 FCGR3A FCGR3B MACF1 CARD11

1.22e-0520011362281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCNJL UGT3A1 FCGR3B UNC5C FAM157B

1.89e-05128113558639cfdc70ff6764adcc5c1ce9eba9d033b8209
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CCNJL UGT3A1 FCGR3B UNC5C FAM157B

1.89e-0512811359b3c57d559a5ed8d590dd89b64a57a3227d8c684
ToppCellCOVID-19_Mild-Classical_Monocyte-|Classical_Monocyte / Disease condition and Cell class

SLAMF8 SELENBP1 CFAP20DC FAM157B BRICD5

1.96e-05129113523b07c71142979d2178fd3a3cdeb3cde73c72c3d
ToppCellCOVID-19_Mild-Classical_Monocyte-|COVID-19_Mild / Disease condition and Cell class

SLAMF8 SELENBP1 CFAP20DC FAM157B BRICD5

2.11e-051311135ae5eb9c013674b36987bf26d4f752dbb374f547b
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLAMF8 SELENBP1 CFAP20DC FAM157B BRICD5

2.44e-0513511357e3c840b40c41715ff7120a88b8b3f223df4f25a
ToppCellCOVID-19_Mild|World / 5 Neutrophil clusters in COVID-19 patients

MATR3 ZCCHC2 FCGR3A FAM157B CSMD1

4.31e-0515211352ff0980dfd8d430cca14649151d856edef115720
ToppCell10x5'-Liver-Lymphocytic_T_CD4-Tfh|Liver / Manually curated celltypes from each tissue

LMNTD2 CFAP20DC CLEC4G FBXO32 BRICD5

4.88e-05156113585bc34ff507f9a66c6e3ba7a3ffd5416d0073ccf
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TTF2 CD200R1 FCGR3A CORO6 CARD11

5.18e-0515811356811dc4f101dfa9a9cc13d949760d43aa522bf3b
ToppCellPBMC-Severe-cDC_1|Severe / Compartment, Disease Groups and Clusters

MATR3 ZNF772 FCGR3B WDR17

5.41e-058111346d1e524f000b71c935359afc801a1d31f218fec8
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BARD1 INTS3 GCSAM P2RX5 CLEC4G

5.50e-0516011358a7a73b0ee1877fe02d47f745d36ae2858b529e1
ToppCelldroplet-Fat-Gat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLAMF8 GCSAM FCGR3B PRCP CLEC4G

5.84e-051621135052f797d8bcab8fc6a43e0bffdd215c88ee12889
ToppCelldroplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLAMF8 RNF130 F5 FCGR3B IL17RA

6.19e-051641135cd0794f84dfd346807e2d803723718b7f22e9232
ToppCelldroplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLAMF8 RNF130 F5 FCGR3B IL17RA

6.19e-05164113512251a49fd4af32d4edb58046245548c260cf04b
ToppCellfacs-MAT-Fat-3m-Myeloid-macrophage|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLAMF8 CD200R1 FCGR3B PRCP CLEC4G

6.19e-051641135b81498c3934e0d52bf0329dc745e02966f9d8613
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC1-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRIM61 PPM1J GCSAM CARD11 MYBL2

6.55e-051661135c8a7d94ed762e5e045ab5f74eef691ddc5f74993
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLAMF8 ROGDI GCSAM P2RX5 CARD11

7.13e-051691135b2d53159e344fad6fcdc485d5b8f6cf1bf094b1f
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLXNA3 GCSAM URB1 CDC20 MYBL2

7.33e-051701135badbe200e9d5003d23d115955b10b4ea767f6c26
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLAMF8 SELENBP1 MST1R FCGR3A FCGR3B

7.33e-0517011357cb7ad9ab064b6ea452545d145e5b1d4090cd4c1
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLAMF8 SELENBP1 MST1R FCGR3A FCGR3B

7.33e-051701135db7cee7e518debb2cbe9eeae05d47e14b69cb8e3
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLAMF8 ROGDI CD200R1 CLEC4G CARD11

7.75e-051721135cabe7b4131d72da87d3caacd8cced3a4f2cbef53
ToppCell367C-Lymphocytic-ILC-ILC-2|367C / Donor, Lineage, Cell class and subclass (all cells)

STK17A PARP8 HIC2 NT5M GCSAM

7.96e-0517311350451450605521fecb27a958628870d268adfb023
ToppCellBac-SEP-Myeloid-cDC1|Bac-SEP / Disease, Lineage and Cell Type

SLAMF8 GCSAM CFAP20DC KIAA1958 DMD

7.96e-051731135f88269327441858ddb8c49b9dd619b76fd53b1da
ToppCellURO-Myeloid-cDC1|URO / Disease, Lineage and Cell Type

SLAMF8 PPA1 PPM1J GCSAM DMD

7.96e-05173113557f4e9f39ef6e02dca76f3dd0b39a0871917ed5a
ToppCell5'-Adult-LargeIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GCSAM CFAP20DC P2RX5 CDC20 MYBL2

7.96e-051731135b7e0193fd4983cb38d1bee441f608f73ee8743b9
ToppCelldroplet-Lung-nan-21m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLAMF8 RNF130 FCGR3B PRCP IL17RA

8.18e-051741135763ca53339d9e236da8463f2a9d1bd39d4385d75
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PKHD1L1 P2RX5 CPT1C CDC20 MYBL2

8.40e-05175113589bf89466191da14896ed8928027f5b911436c22
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MATR3 RETREG3 FCGR3A FCGR3B MACF1

8.87e-051771135d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MATR3 RETREG3 FCGR3A FCGR3B MACF1

8.87e-051771135f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCellAdult-Epithelial-club_cell-D175|Adult / Lineage, Cell type, age group and donor

CCNJL FRAS1 SHC4 NT5M C4BPA

8.87e-051771135d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCellCOVID-19_Mild-Lymphoid_T/NK-NK_activated|COVID-19_Mild / Disease group, lineage and cell class

MATR3 RETREG3 FCGR3A FCGR3B MACF1

8.87e-0517711356978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

PKHD1L1 GCSAM P2RX5 MYBL2 FBXW7

8.87e-051771135ae2d2e138946535596fa30a55207f261cafda461
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

MATR3 RETREG3 FCGR3A FCGR3B MACF1

8.87e-051771135936ab2b180a052387124f68d0c7f41c0b164e748
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MATR3 RETREG3 FCGR3A FCGR3B MACF1

8.87e-051771135d5aeda113afaa2425874394610344570c9078478
ToppCelldroplet-Spleen-nan-21m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHC4 CFAP20DC CPT1C ZC3HAV1L CDC20

9.35e-051791135dabecd283c1f0f71a66b804c99be8bd48ea36e35
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

ADAMTSL1 NTRK2 UNC5C FBXO32 DMD

9.60e-051801135d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-cDC1|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLAMF8 ROGDI PPA1 PPM1J GCSAM

9.85e-05181113584ca8c9c036478a6d3a2071919d09065455d417c
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

BARD1 NPY4R ITGB1BP2 CARD11

1.01e-04951134ffbf3e362384c87b9db690ed39cd215e1f68375c
ToppCellT_cells-Resident_memory_CD8+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

SLAMF8 NBEAL1 STK17A PARP8 PACS2

1.01e-041821135111d434b89902ec11fb07f41b8ee1a98f3991b61
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

PARP8 MATR3 FCGR3A FCGR3B MACF1

1.04e-041831135f593a89b0aa8fffdfa403769916facfd30358521
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-NK_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STK17A PARP8 FCGR3A FCGR3B CARD11

1.04e-041831135b902390614fe924d48511e4187b36a0b49b08f23
ToppCellCOVID-19_Mild-NK_activated|COVID-19_Mild / Disease condition and Cell class

MATR3 RETREG3 FCGR3A FCGR3B MACF1

1.04e-04183113522bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-Pre-B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAG2 GCSAM P2RX5 CARD11 MYBL2

1.04e-04183113532880e71adba1b63fa9ec8530a8d4e46cc277c3a
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 NEB PKHD1L1 DMD CSMD1

1.06e-0418411352cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 NEB PKHD1L1 DMD CSMD1

1.06e-041841135ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 NEB PKHD1L1 DMD CSMD1

1.06e-0418411352b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

TTF2 CD46 URB1 MACF1 IFT80

1.09e-041851135a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

TTF2 CD46 URB1 MACF1 IFT80

1.12e-0418611358571956890fc9894d766ba294a28e376b4aba428
ToppCellHealthy-multiplets|Healthy / disease group, cell group and cell class

SLAMF8 PPM1J PKHD1L1 GCSAM CDC20

1.12e-0418611352ec999b97e95afb898f8083042b0f188d3d234bc
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

BCAS3 P2RX5 KIAA1958 PACS2 CCDC180

1.12e-04186113574eb69a52090f9e2426a47e03a1c478ee0cfec18
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

BCAS3 P2RX5 KIAA1958 PACS2 CCDC180

1.15e-0418711351eed2c1a05e80a7c8f639437c117afe0c18dfb0c
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 BARD1 CD46 CSMD1 FZD2

1.21e-041891135544d95df910f1b276995624509a7e41b219baca0
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-NK_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STK17A PARP8 GCSAM FCGR3A CARD11

1.21e-0418911355a9c3c61998efc40a5d2042e0f568b52103734a9
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-VLMC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ADAMTSL1 SELENBP1 GASK1B PTH2R FBXO32

1.24e-041901135c90410bb47b8da774dee2a3502f667ce9a7c97d9
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-VLMC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ADAMTSL1 SELENBP1 GASK1B PTH2R FBXO32

1.24e-041901135bc44727e8458a02fae95dc5515b708000d2ee8c4
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 MAGI3 F5 KIAA1958 MED13

1.33e-041931135503a979328c68b096680b71359a26f02fafdff35
ToppCellParenchymal-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLAMF8 RAG2 NTRK2 UNC5C PHF21B

1.33e-041931135df4afb4848eb9d7d8d39e5c612919663cbbb2514
ToppCellParenchymal-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLAMF8 RAG2 NTRK2 UNC5C PHF21B

1.33e-041931135ab36d684bde8fe77d11a5188425135328052c58b
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

SELENBP1 NTRK2 PTH2R PRCP FBXO32

1.36e-0419411357c6c0376603e5fcb64814fd6204d153629c2fbf5
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RNF130 PPA1 CD200R1 PRCP FZD2

1.36e-0419411356af2971d83f5ad6aed16d0ceb8bfc52f3947bc10
ToppCellControl-Classical_Monocyte|Control / Disease condition and Cell class

NBEAL1 PARP8 F5 GASK1B IL17RA

1.36e-0419411359e33e1b54b4114f9e6981819834bb796ed7192b5
ToppCell(7)_MNP-(7)_DC_1|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)

SLAMF8 PPA1 PPM1J GCSAM DMD

1.36e-0419411358dbe0188e2af6f14b3b44e5213fbdd581128082f
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNF130 PPA1 CD200R1 PRCP FZD2

1.36e-0419411355c60670ec24470225fabaa6071fdb4ef6e579840
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NTRK2 UNC5C CORO6 FBXO32 DMD

1.36e-0419411355c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCellBLOOD--(1)_T_cell-(1)_Activated_T_cells|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

BARD1 F5 WDR1 CDC20 MYBL2

1.36e-0419411356a0cbb9d5c5c4effb02dff654c6c3b184026875c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NTRK2 UNC5C CORO6 FBXO32 DMD

1.36e-041941135ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCellPBMC-Control|PBMC / Compartment, Disease Groups and Clusters

ROGDI NBEAL1 CD200R1 FCGR3A CLEC4G

1.40e-0419511353cc4afa5f68f28336310d5f80a082cb8d98a5679
Diseaselevel of low affinity immunoglobulin gamma Fc region receptor III-A in blood serum

FCGR3A FCGR3B

1.28e-0521062OBA_2040305
DiseaseSeptic Phlebitis, Sagittal Sinus

F5 PROS1

3.83e-0531062C0751823
DiseaseSagittal Sinus Thrombophlebitis

F5 PROS1

3.83e-0531062C0751824
DiseaseLupus Vasculitis, Central Nervous System

FCGR3A FCGR3B

3.83e-0531062C0752332
DiseaseLupus Meningoencephalitis

FCGR3A FCGR3B

3.83e-0531062C0752334
DiseaseNeuropsychiatric Systemic Lupus Erythematosus

FCGR3A FCGR3B

3.83e-0531062C0752335
DiseaseSagittal Sinus Thrombosis

F5 PROS1

3.83e-0531062C0338575
Diseaseneuroblastoma

PARP8 BARD1 MLYCD FBXO32 CSMD1

6.36e-051161065EFO_0000621
Diseaselow affinity immunoglobulin gamma Fc region receptor II-a/b measurement

FCGR3A FCGR3B

2.65e-0471062EFO_0008211
Diseasecerebrospinal fluid clusterin measurement

MAGI3 FAM124A CSMD1

2.71e-04351063EFO_0007657
Diseasevenous thromboembolism, factor VII measurement

TTF2 F5 C4BPA

3.47e-04381063EFO_0004286, EFO_0004619
DiseaseThrombophilia due to thrombin defect

F5 PROS1

3.53e-0481062cv:C3160733
Diseaseasparaginase-induced acute pancreatitis

NEB CDC20

4.53e-0491062EFO_1001507
Diseaseplexin-B2 measurement

FCGR3A FCGR3B

4.53e-0491062EFO_0021867
Diseasevenous thromboembolism, von Willebrand factor measurement

TTF2 F5 C4BPA

4.67e-04421063EFO_0004286, EFO_0004629
DiseaseRS-10-hydroxywarfarin to RS-warfarin ratio measurement

FRAS1 PRCP UNC5C SMAD4

6.78e-041101064EFO_0803335
DiseaseMammary Ductal Carcinoma

ERBB2 SMAD4

6.88e-04111062C0021367
DiseaseInvasive Ductal Breast Carcinoma

ERBB2 SMAD4

6.88e-04111062C1134719
DiseaseThromboembolism

F5 PROS1

8.24e-04121062C0040038
DiseaseErythrocyte Mean Corpuscular Hemoglobin Test

MLYCD AGL

9.72e-04131062C0369183
DiseaseFinding of Mean Corpuscular Hemoglobin

MLYCD AGL

9.72e-04131062C1261502
Diseaseovarian cancer (is_implicated_in)

ERBB2 BARD1 SMAD4

1.09e-03561063DOID:2394 (is_implicated_in)
Diseaselow affinity immunoglobulin gamma Fc region receptor III-B measurement

FCGR3A FCGR3B

1.13e-03141062EFO_0008212
Diseaseamygdala volume change measurement

PARP8 CSMD1

1.48e-03161062EFO_0021490
DiseaseBlood Coagulation Disorders

F5 SMAD4

1.48e-03161062C0005779
Diseaselow affinity immunoglobulin gamma Fc region receptor II-a measurement

FCGR3A FCGR3B

1.68e-03171062EFO_0021969
DiseaseIschemic stroke, venous thromboembolism, stroke, Abnormal thrombosis, deep vein thrombosis, pulmonary embolism

TTF2 F5

1.68e-03171062EFO_0000712, EFO_0003827, EFO_0003907, EFO_0004286, HP_0001977, HP_0002140
Diseaseautoimmune thyroid disease, type 1 diabetes mellitus

MAGI3 QRFPR

1.88e-03181062EFO_0006812, MONDO_0005147
Diseasejoint damage measurement

CCNJL PARP8 CSMD1

1.91e-03681063EFO_0005413
DiseaseMalignant Glioma

ERBB2 NTRK2 FBXW7

2.07e-03701063C0555198
Diseasemixed gliomas

ERBB2 NTRK2 FBXW7

2.07e-03701063C0259783
Diseasecolorectal adenoma (is_marker_for)

F5 SMAD4

2.33e-03201062DOID:0050860 (is_marker_for)
Diseaseprothrombin time measurement

TTF2 F5

2.57e-03211062EFO_0008390
DiseaseNasopharyngeal carcinoma

ERBB2 MST1R

2.82e-03221062C2931822
Diseasesorbitol measurement

ADAMTSL1 AIPL1

3.08e-03231062EFO_0010533
DiseaseCarcinoma of lung

ERBB2 NTRK2

3.08e-03231062C0684249
DiseaseIntrahepatic Cholangiocarcinoma

ERBB2 SMAD4

3.35e-03241062C0345905
Diseaseairway responsiveness measurement

BCAS3 CSMD1

3.35e-03241062EFO_0006897
DiseaseExtrahepatic Cholangiocarcinoma

ERBB2 SMAD4

3.35e-03241062C3805278

Protein segments in the cluster

PeptideGeneStartEntry
SSVIHCDADSKWNPS

C4BPA

276

P04003
NTHLCFVHTVPWDQL

ERBB2

471

P04626
VDAHSQVCSILWSPH

CDC20

396

Q12834
KDPTEWHVHTCGLAN

AIPL1

111

Q9NZN9
KHFQHIQVCTPWLEA

ALG1

336

Q9BT22
VKDHAGWTPLHEACN

BARD1

456

Q99728
SLHCEWIIEAKPGHS

CSMD1

781

Q96PZ7
KVQEAWVPSQDTHHT

BRICD5

146

Q6PL45
SVSQKDHHCHTWPTT

CCNJL

206

Q8IV13
DHHCHTWPTTCPRKT

CCNJL

211

Q8IV13
SPKQRTSRCWDHHIA

GCSAM

26

Q8N6F7
HETQTTCWDHPKMTE

DMD

3076

P11532
NTKWPTHHCDKDPSQ

CCDC180

1266

Q9P1Z9
PIKSHEVHWETCRTV

CER1

151

O95813
HVPHGAEEAALTCWK

DHX32

521

Q7L7V1
ILTHPWSSSQCAVHH

BCAS3

381

Q9H6U6
PDHSFCDSLWHNITV

NBEAL1

656

Q6ZS30
HRTTEKWNSVADCLP

RAG2

166

P55895
SFHSLPSWIEECKQH

RAB33B

121

Q9H082
KEHICCLEEWTSPVH

QRFPR

196

Q96P65
FHKSCVDPWLSEHCT

RNF130

286

Q86XS8
CHPDDQFTTSILRHW

INTS3

866

Q68E01
SDQHAEPWVVSGCHS

ANAPC7

301

Q9UJX3
TVKNSTCLDDSWIHP

IL17RA

51

Q96F46
KHGEIWVVPNTDHVC

PARP8

801

Q8N3A8
IHEHGTEWASSPCSV

FRAS1

101

Q86XX4
HKGENTETSPHDCEW

HCFC2

266

Q9Y5Z7
CDLPVHSNKEWSQHI

MATR3

296

P43243
SWSDHKHLAQPDTAV

MAGI3

991

Q5TCQ9
THTICDRNHTWLPVS

CD46

76

P15529
GKQLPASCRHDWHQT

ITGB1BP2

211

Q9UKP3
ADKVVCTESWPLAHH

NPY4R

196

P50391
SEEWSCVLNKISTHP

FAM182A

131

Q5T1J6
RHDWHTLCKDLPNAT

IL17RE

306

Q8NFR9
TWHSPCEVLQKISEA

MLYCD

201

O95822
HARTNKAVPEHLCSW

ADAMTSL1

1696

Q8N6G6
PSERCSSHWAAHKDS

FAM124A

446

Q86V42
LQAEPHQHGCWTVTE

ISM2

71

Q6H9L7
ISDPDVRHTWKSNCL

PLXNA3

1706

P51805
VCTLHGHTSWVKNIE

DCAF10

246

Q5QP82
ERSWVSQHCKSLAIP

FZD2

491

Q14332
PHCSESIHRSWDAIN

PRCP

231

P42785
VCHPDCITTIKHWIT

MACF1

2966

O94854
GTVTVKSTCHWEVHN

CD200R1

196

Q8TD46
HHKTVEWGSLPCLNT

LMNTD2

261

Q8IXW0
LAAQWSSHVKHFPIC

PACS2

866

Q86VP3
IPSEHHEAITCLEWD

MED16

76

Q9Y2X0
QVHVEVPKSHWSCGL

PLA2G4E

271

Q3MJ16
LSVEHSWADCPISGH

CPT1C

466

Q8TCG5
KPESGCTEIHHHEWS

GASK1B

351

Q6UWH4
ETVSKSVCAEPWRHQ

FAM157B

311

P0CG42
PKHQELVSCVGWTTA

IFT80

11

Q9P2H3
DLHCVLVTNPHSSQW

GADD45A

121

P24522
WDPETETCLHTLQGH

FBXW7

526

Q969H0
TVEHLAIQCHWSQRP

DDX50

361

Q9BQ39
DDMHPDVIHSVCWNS

CORO6

171

Q6QEF8
EDPIHLRCHSWKNTA

FCGR3B

121

O75015
WSDCISVEHRPGTHD

MARCHF10

421

Q8NA82
ESACTVPTDVDKWFH

PPA1

271

Q15181
EDPIHLRCHSWKNTA

FCGR3A

121

P08637
HILSWKGTDHPCTAN

FBXO32

321

Q969P5
VPLDTCTKEEAHWTI

CARD11

726

Q9BXL7
WNCDLDKAASECHPH

P2RX5

261

Q93086
TPSWEHVLFTACHNQ

NT5M

186

Q9NPB1
DPATLRQHEKTHWLT

HIC2

516

Q96JB3
WDLSTETPHFTCKGH

NLE1

141

Q9NVX2
VSHVHKVECVIPWLN

ROGDI

241

Q9GZN7
TMPDITVCAHDHISW

F5

241

P12259
SHIPAGDCSEHWKTQ

NIN

136

Q8N4C6
HNHLNPEVKKSCWTE

MYBL2

126

P10244
KVCIGAVWHPHETSK

CDC40

551

O60508
AVWHPHETSKVITCG

CDC40

556

O60508
QSIKETPCWIEIHLH

SMAD4

516

Q13485
PQSCWSSQKEVSHES

PPM1J

216

Q5JR12
PNLKDELHHSGWNTC

SELENBP1

66

Q13228
WHSVKQTICLPEKSH

SPATA31D4

851

Q6ZUB0
EHKKTITAISWCPHN

WDR17

81

Q8IZU2
HHAKIVCLAWSPDNE

WDR1

531

O75083
ISTHEHLAWVTCLPE

SEBOX

46

Q9HB31
VDEALVKSSCLHPWS

MED13

1251

Q9UHV7
DTTHSPWHLEASCTL

INTS5

896

Q6P9B9
SKHNDIRAHSCPSVW

PROS1

656

P07225
TWLAIKCSPSLHVDD

RIPK4

46

P57078
WGPAAVEHHKTCRSL

URB1

1566

O60287
TAEECLKHPWLTQSS

STK17A

311

Q9UEE5
TWCPTSISHLKEAEE

ABHD5

26

Q8WTS1
DSCNPSHLWLEASKE

CFAP20DC

321

Q6ZVT6
VPKTTWAAAQDHCAD

CLEC4G

181

Q6UXB4
TSDHHWCIPFTVKGN

NTRK2

296

Q16620
DWRKQSCTTIQHPEH

ZCCHC2

541

Q9C0B9
SVPELCHHVAEVWVS

RETREG3

136

Q86VR2
SHSLPHIKQQLWSEE

SHC4

511

Q6S5L8
LSTDHQHHCVWPIKK

TRIM61

121

Q5EBN2
WHSVKQTICLPEKSH

SPATA31D3

851

P0C874
CQSSHWPRDVHLATN

UGT3A1

331

Q6NUS8
EDPCWKNEITHDEHC

PHF21B

341

Q96EK2
VHEDCPLLSDQAWHV

PAPLN

476

O95428
QDPCSWVDKLSTVHH

TMEM144

171

Q7Z5S9
QHFLTCPSSTDEKAW

SNX18

376

Q96RF0
ISHWPNECIRHSASV

nan

81

Q8N8P6
ADKVVCTESWPLAHH

NPY4R2

196

P0DQD5
WVLTAAHCTKDASDP

TMPRSS12

116

Q86WS5
TDAHTLSGWAPVCVH

PKHD1L1

2146

Q86WI1
LATVTPWDSCHHEAA

SLAMF8

211

Q9P0V8
VWSNSEQDCLPHSFH

PTH2R

496

P49190
PSVCQRHEKTHWRET

ZNF563

461

Q8TA94
SESHSHWVHSPIECT

EDA2R

241

Q9HAV5
HWVHSPIECTELDLQ

EDA2R

246

Q9HAV5
CHQWLRPETHTKEQI

ZSCAN12

71

O43309
VLTMHHCADPNTEDW

UNC5C

606

O95185
SWQQDHCPPKLTEFH

MST1R

561

Q04912
EWKPHSNTKCEEASH

ZNF772

246

Q68DY9
IICPASLIHHWKNEV

TTF2

646

Q9UNY4
CWSTCTLSHDIHTPV

ZC3HAV1L

121

Q96H79
TAANSKWIQEHPECA

AGL

221

P35573
VSWAHSHGTICSLIP

KIAA1958

16

Q8N8K9
LHQWTCLPDQSDVIH

NEB

2871

P20929