Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR5P2 OR51E2 CMKLR2 GPR3 OR52I2 OR52I1 OR4S1 NPY2R OR12D2 OR4A8 OR12D1 GPR32 GPR32P1 BRS3 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 GPR173 GPR85 OR52N4 OR8K5 OR4E2 OR4E1 OR4C45 MC4R OR1E1 ADGRD2 TAS2R39 OR52P1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	6.28e-25	884	93	36	GO:0004930
GeneOntologyMolecularFunction	olfactory receptor activity	OR5P2 OR51E2 OR52I2 OR52I1 OR4S1 OR12D2 OR4A8 OR12D1 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 OR52N4 OR8K5 OR4E2 OR4E1 OR4C45 OR1E1 OR52P1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	8.83e-21	431	93	25	GO:0004984
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR5P2 OR51E2 CMKLR2 GPR3 OR52I2 OR52I1 OR4S1 NPY2R OR12D2 OR4A8 OR12D1 GPR32 GPR32P1 BRS3 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 GPR173 GPR85 OR52N4 OR8K5 OR4E2 OR4E1 OR4C45 MC4R OR1E1 ADGRD2 TAS2R39 OR52P1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	9.22e-19	1353	93	36	GO:0004888
GeneOntologyMolecularFunction	odorant binding	OR5P2 OR12D2 OR12D1 OR9Q1 OR8K5 OR4E2 OR4E1 OR5D13 OR8G2P	7.85e-09	127	93	9	GO:0005549
GeneOntologyMolecularFunction	N-formyl peptide receptor activity	GPR32 GPR32P1	2.13e-04	5	93	2	GO:0004982
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	NPY2R GPR32 GPR32P1 BRS3 MC4R	3.95e-04	133	93	5	GO:0008528
GeneOntologyMolecularFunction	peptide receptor activity	NPY2R GPR32 GPR32P1 BRS3 MC4R	5.00e-04	140	93	5	GO:0001653
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR5P2 OR51E2 OR52I2 OR52I1 OR4S1 OR12D2 OR4A8 OR12D1 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 OR52N4 OR8K5 OR4E2 OR4E1 OR4C45 OR1E1 TAS2R39 OR52P1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	4.26e-21	485	93	26	GO:0050907
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR5P2 OR51E2 OR52I2 OR52I1 OR4S1 OR12D2 OR4A8 OR12D1 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 OR52N4 OR8K5 OR4E2 OR4E1 OR4C45 OR1E1 OR52P1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	4.34e-21	432	93	25	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR5P2 OR51E2 OR52I2 OR52I1 OR4S1 OR12D2 OR4A8 OR12D1 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 OR52N4 OR8K5 OR4E2 OR4E1 OR4C45 OR1E1 OR52P1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	2.58e-20	465	93	25	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR5P2 OR51E2 OR52I2 OR52I1 OR4S1 OR12D2 OR4A8 OR12D1 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 OR52N4 OR8K5 OR4E2 OR4E1 OR4C45 OR1E1 TAS2R39 OR52P1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	2.96e-20	524	93	26	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR5P2 OR51E2 OR52I2 OR52I1 OR4S1 OR12D2 OR4A8 OR12D1 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 OR52N4 OR8K5 OR4E2 OR4E1 OR4C45 OR1E1 TAS2R39 OR52P1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	8.62e-20	547	93	26	GO:0007606
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR5P2 OR51E2 CMKLR2 GPR3 OR52I2 OR52I1 OR4S1 NPY2R OR12D2 OR4A8 OR12D1 GPR32 GPR32P1 BRS3 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 GPR173 GPR85 OR52N4 OR8K5 OR4E2 OR4E1 OR4C45 MC4R OR1E1 ADGRD2 TAS2R39 PDE10A OR52P1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	9.53e-20	1395	93	37	GO:0007186
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR5P2 OR51E2 OR52I2 OR52I1 OR4S1 OR12D2 OR4A8 OR12D1 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 OR52N4 OR8K5 OR4E2 OR4E1 OR4C45 OR1E1 TAS2R39 OR52P1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	4.01e-19	582	93	26	GO:0050906
GeneOntologyBiologicalProcess	detection of stimulus	OR5P2 OR51E2 OR52I2 OR52I1 OR4S1 OR12D2 OR4A8 OR12D1 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 OR52N4 OR8K5 OR4E2 OR4E1 OR4C45 OR1E1 TAS2R39 OR52P1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	7.75e-17	722	93	26	GO:0051606
GeneOntologyBiologicalProcess	sensory perception	OR5P2 OR51E2 OR52I2 OR52I1 OR4S1 OR12D2 OR4A8 OR12D1 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 OR52N4 OR8K5 OR4E2 OR4E1 OR4C45 OR1E1 ATP8B1 TAS2R39 OR52P1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	1.11e-13	1072	93	27	GO:0007600
Domain	GPCR_Rhodpsn_7TM	OR5P2 OR51E2 CMKLR2 GPR3 OR52I2 OR52I1 OR4S1 NPY2R OR12D2 GPR32 BRS3 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 GPR173 GPR85 OR52N4 OR8K5 OR4E2 MC4R OR1E1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	1.33e-19	670	87	28	IPR017452
Domain	7tm_1	OR5P2 OR51E2 CMKLR2 GPR3 OR52I2 OR52I1 OR4S1 NPY2R OR12D2 GPR32 BRS3 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 GPR173 GPR85 OR52N4 OR8K5 OR4E2 MC4R OR1E1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	1.76e-19	677	87	28	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR5P2 OR51E2 CMKLR2 GPR3 OR52I2 OR52I1 OR4S1 NPY2R OR12D2 GPR32 BRS3 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 GPR173 GPR85 OR52N4 OR8K5 OR4E2 MC4R OR1E1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	2.40e-19	685	87	28	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR5P2 OR51E2 CMKLR2 GPR3 OR52I2 OR52I1 OR4S1 NPY2R OR12D2 GPR32 BRS3 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 GPR173 GPR85 OR52N4 OR8K5 OR4E2 MC4R OR1E1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	3.01e-19	691	87	28	PS50262
Domain	GPCR_Rhodpsn	OR5P2 OR51E2 CMKLR2 GPR3 OR52I2 OR52I1 OR4S1 NPY2R OR12D2 GPR32 BRS3 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 GPR173 GPR85 OR52N4 OR8K5 OR4E2 MC4R OR1E1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	3.13e-19	692	87	28	IPR000276
Domain	Olfact_rcpt	OR5P2 OR51E2 OR52I2 OR52I1 OR4S1 OR12D2 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 OR52N4 OR8K5 OR4E2 OR1E1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	1.17e-15	393	87	20	IPR000725
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR5P2 OR51E2 OR52I2 OR52I1 OR4S1 OR12D2 OR4A8 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 OR52N4 OR8K5 OR4E2 OR4E1 OR4C45 OR1E1 OR52N1 OR52B6 OR5D13 OR52E2	1.06e-17	417	67	22	M4072
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR5P2 OR51E2 OR52I2 OR52I1 OR4S1 OR12D2 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 OR52N4 OR8K5 OR4E2 OR4C45 OR1E1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	4.30e-17	389	67	21	M14091
Pathway	REACTOME_SENSORY_PERCEPTION	OR5P2 OR51E2 OR52I2 OR52I1 OR4S1 OR12D2 OR4A8 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 OR52N4 OR8K5 OR4E2 OR4E1 OR4C45 OR1E1 TAS2R39 OR52N1 OR52B6 OR5D13 LRRC52 OR52E2	5.17e-16	636	67	24	M41834
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	CMKLR2 GPR3 NPY2R GPR32 BRS3 OR7C1 GPR173 GPR85 MC4R OR1E1	3.77e-07	260	67	10	M39397
Pathway	WP_GPCRS_ODORANT	OR5P2 CMKLR2 GPR3 BRS3 GPR173 GPR85 OR1E1 TAS2R39	7.40e-07	157	67	8	MM15872
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR5P2 OR51E2 OR52I2 OR52I1 OR12D2 OR4A8 OR12D1 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 OR52N4 OR8K5 OR4E2 OR4E1 OR4C45 OR1E1 OR52P1 OR5D13 OR8G2P OR52E2	2.40e-24	343	93	22	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR5P2 OR51E2 OR52I2 OR52I1 OR12D2 OR4A8 OR12D1 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 OR52N4 OR8K5 OR4E2 OR4E1 OR4C45 OR1E1 OR52P1 OR5D13 OR8G2P OR52E2	2.91e-24	346	93	22	14611657
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR5P2 OR51E2 OR52I2 OR52I1 OR12D2 OR4A8 OR12D1 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 OR52N4 OR8K5 OR4E2 OR4E1 OR4C45 OR1E1 OR52P1 OR8G2P OR52E2	6.53e-23	340	93	21	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR5P2 OR51E2 OR52I2 OR52I1 OR12D2 OR4A8 OR12D1 OR7C1 OR4A47 OR6C75 OR9Q1 OR52N2 OR52N4 OR8K5 OR4E2 OR4E1 OR4C45 OR1E1 OR52P1 OR8G2P OR52E2	6.53e-23	340	93	21	11802173
Pubmed	The human olfactory receptor gene family.	OR5P2 OR51E2 OR52I2 OR52I1 OR4S1 OR12D2 OR4A8 OR7C1 OR4A47 OR52N2 OR52N4 OR8K5 OR4E2 OR4E1 OR1E1 OR52P1 OR52N1 OR52B6 OR5D13 OR8G2P OR52E2	9.54e-19	541	93	21	14983052
Pubmed	Odorant and vomeronasal receptor genes in two mouse genome assemblies.	OR5P2 OR12D2 OR4A8 OR12D1 OR7C1 OR52N2 OR52N4 OR8K5 OR4E1 OR1E1 OR5D13	9.87e-17	74	93	11	15081110
Pubmed	Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse.	OR5P2 OR51E2 OR52I2 OR52I1	1.85e-06	33	93	4	17350283
Pubmed	Personal receptor repertoires: olfaction as a model.	OR12D2 OR4A8 OR12D1 OR5D13	3.30e-06	38	93	4	22908908
Pubmed	Correlations of MC4R and MSH2 expression with obesity in colon cancer patients.	MC4R MSH2	7.07e-06	2	93	2	28537674
Pubmed	Mutually exclusive expression of odorant receptor transgenes.	OR4E2 OR4E1	7.07e-06	2	93	2	10862701
Pubmed	BRS3 in both MC4R- and SIM1-expressing neurons regulates energy homeostasis in mice.	BRS3 MC4R	7.07e-06	2	93	2	32229422
Pubmed	Negative feedback regulation ensures the one receptor-one olfactory neuron rule in mouse.	OR4E2 OR4E1	7.07e-06	2	93	2	14593185
Pubmed	Olfactory neurons expressing closely linked and homologous odorant receptor genes tend to project their axons to neighboring glomeruli on the olfactory bulb.	OR4E2 OR4E1	7.07e-06	2	93	2	10493742
Pubmed	High-throughput screening of mouse knockout lines identifies true lean and obese phenotypes.	BRS3 SCD MC4R	8.23e-06	15	93	3	18719666
Pubmed	Cloning genes encoding receptors related to chemoattractant receptors.	GPR32 GPR32P1	2.12e-05	3	93	2	9653656
Pubmed	ES cell differentiation system recapitulates the establishment of imprinted gene expression in a cell-type-specific manner.	S100B PLP1	2.12e-05	3	93	2	22156770
Pubmed	Cloning of human genes encoding novel G protein-coupled receptors.	CMKLR2 GPR3	2.12e-05	3	93	2	7851889
Pubmed	An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system.	GPR173 GPR85	2.12e-05	3	93	2	10833454
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR7C1 OR4A47 OR9Q1 OR4E2 OR4E1 OR1E1	2.81e-05	219	93	6	12213199
Pubmed	Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.	OR7C1 OR1E1 OR8G2P	3.60e-05	24	93	3	9119360
Pubmed	Polymorphisms in the NPY2R gene show significant associations with BMI that are additive to FTO, MC4R, and NPFFR2 gene effects.	NPY2R MC4R	4.23e-05	4	93	2	21818152
Pubmed	Embryonic to adult conversion of neural cell adhesion molecules in normal and staggerer mice.	RORA PLP1	4.23e-05	4	93	2	6960362
Pubmed	A gene expression map of human chromosome 21 orthologues in the mouse.	ABCC1 S100B SYNJ1 LTN1 DOP1B	6.84e-05	158	93	5	12466855
Pubmed	Regulation of energy homeostasis by bombesin receptor subtype-3: selective receptor agonists for the treatment of obesity.	BRS3 MC4R	7.04e-05	5	93	2	20096642
Pubmed	Local and cis effects of the H element on expression of odorant receptor genes in mouse.	OR4E2 OR4E1	7.04e-05	5	93	2	17662950
Pubmed	Molecular Mechanism Underlying the Action of Zona-pellucida Glycoproteins on Mouse Sperm.	SLC9B1 LRRC52	1.05e-04	6	93	2	32984353
Pubmed	Novel human G-protein-coupled receptors.	OR52I2 OR52I1	1.47e-04	7	93	2	12732197
Pubmed	Polymorphisms in neuropeptide genes and bone mineral density in Korean postmenopausal women.	NPY2R MC4R	1.47e-04	7	93	2	25871004
Pubmed	Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy.	S100B PLP1	1.96e-04	8	93	2	15102707
Pubmed	Interleukin-1 hyperproduction by in vitro activated peripheral macrophages from cerebellar mutant mice.	RORA PLP1	1.96e-04	8	93	2	2230805
Pubmed	Time-controlled transcardiac perfusion cross-linking for the study of protein interactions in complex tissues.	DPP6 PDE10A PLP1	1.97e-04	42	93	3	15146195
Pubmed	Peripheral macrophage abnormalities in mutant mice with spinocerebellar degeneration.	RORA PLP1	3.14e-04	10	93	2	1565842
Pubmed	The chromosomal distribution of mouse odorant receptor genes.	OR4E2 OR4E1 OR1E1	4.16e-04	54	93	3	8570653
Pubmed	A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.	OR4S1 VPS13C KDM2B	4.39e-04	55	93	3	22581228
Pubmed	Analysis of the 1.1-Mb human alpha/delta T-cell receptor locus with bacterial artificial chromosome clones.	OR4E2 OR4E1	4.59e-04	12	93	2	9110172
Pubmed	Co-duplication of olfactory receptor and MHC class I genes in the mouse major histocompatibility complex.	OR12D2 OR12D1	5.41e-04	13	93	2	14506126
Pubmed	BMP signaling mutant mice exhibit glial cell maturation defects.	S100B PLP1	6.30e-04	14	93	2	17391983
Pubmed	Gene mapping of sperm quality parameters in recombinant inbred strains of mice.	LIPG MC4R	6.30e-04	14	93	2	18311719
Pubmed	Enhancer interaction networks as a means for singular olfactory receptor expression.	OR4E2 OR4E1	6.30e-04	14	93	2	25417106
Pubmed	Neurogenin3 participates in gliogenesis in the developing vertebrate spinal cord.	S100B PLP1	7.26e-04	15	93	2	12490199
Pubmed	LC-MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line.	ABCC1 SLC47A1	7.26e-04	15	93	2	28112518
Pubmed	A vagal reflex evoked by airway closure.	NPY2R MC4R	8.28e-04	16	93	2	38448588
Pubmed	Chromosomal location-dependent nonstochastic onset of odor receptor expression.	OR6C75 OR4E1	9.37e-04	17	93	2	20668191
Pubmed	Glial origin of mesenchymal stem cells in a tooth model system.	S100B PLP1	9.37e-04	17	93	2	25079316
Pubmed	Human chromosome 21 gene expression atlas in the mouse.	S100B SYNJ1 LTN1 DOP1B	9.82e-04	163	93	4	12466854
Pubmed	Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters.	ABCC1 SLC47A1	1.05e-03	18	93	2	31791063
Pubmed	CAMSAP3 is required for mTORC1-dependent ependymal cell growth and lateral ventricle shaping in mouse brains.	S100B CAMSAP3	1.05e-03	18	93	2	33462112
Pubmed	Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders.	SYNJ1 VPS13C	1.05e-03	18	93	2	27984743
Pubmed	The Stimulus-Dependent Gradient of Cyp26B1+ Olfactory Sensory Neurons Is Necessary for the Functional Integrity of the Olfactory Sensory Map.	OR51E2 OR4E1	1.05e-03	18	93	2	26446231
Pubmed	Sequential arrival and graded secretion of Sema3F by olfactory neuron axons specify map topography at the bulb.	OR4E2 OR4E1	1.05e-03	18	93	2	20550939
Pubmed	Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription.	OR4E1 RORA	1.17e-03	19	93	2	31442405
Pubmed	Human chromosome 11 DNA sequence and analysis including novel gene identification.	OR4A8 OR4A47 MS4A15	1.31e-03	80	93	3	16554811
Pubmed	Mice with megalencephalic leukoencephalopathy with cysts: a developmental angle.	S100B PLP1	1.44e-03	21	93	2	25382142
Pubmed	Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection.	S100B PLP1	1.58e-03	22	93	2	11955448
Pubmed	An atlas of genetic influences on human blood metabolites.	ABCC1 LIPG TKT SCD	1.73e-03	190	93	4	24816252
Pubmed	The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.	OR7C1 OR1E1	1.73e-03	23	93	2	10706615
Pubmed	Sox2 Acts in Thalamic Neurons to Control the Development of Retina-Thalamus-Cortex Connectivity.	S100B RORA	1.73e-03	23	93	2	31082736
Pubmed	Local regulation of fat metabolism in peripheral nerves.	SCD PLP1	1.73e-03	23	93	2	14522948
Pubmed	Brg1 is required for murine neural stem cell maintenance and gliogenesis.	S100B PLP1	1.88e-03	24	93	2	16330018
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	SLC30A7 CCDC47 SCD VPS13C STARD3 DOP1B	2.37e-03	504	93	6	34432599
Pubmed	Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures.	OR8K5 OR8G2P	2.38e-03	27	93	2	32061665
Pubmed	Parkinson Disease Overview	SYNJ1 VPS13C	2.38e-03	27	93	2	20301402
Pubmed	Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence.	OR51E2 DPP6 S100B BIRC6	2.52e-03	211	93	4	7566098
Interaction	GPR182 interactions	CCDC47 SCD AP5Z1 TMC6 LTN1 PIGG MICU2 TMEM184B TAP2 DOP1B	6.16e-06	455	74	10	int:GPR182
Interaction	CLEC2D interactions	SLC22A23 STARD3 SLC47A1 PIGG TMEM184B PLP1 DOP1B	7.93e-06	197	74	7	int:CLEC2D
Interaction	GPR173 interactions	SLC30A7 GPR173 STARD3 PIGG	3.67e-05	51	74	4	int:GPR173
Cytoband	11p15.4	OR5P2 OR52I2 OR52I1 OR52N2 OR52N4 OR52P1 OR52N1 OR52B6 OR52E2	3.31e-10	200	93	9	11p15.4
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	OR5P2 OR51E2 OR52I2 OR52I1 OR52N2 OR52N4 ANO5 OR52P1 OR52N1 OR52B6 OR52E2	2.15e-08	564	93	11	chr11p15
Cytoband	6p22.2-p21.31	OR12D2 OR12D1	4.04e-05	5	93	2	6p22.2-p21.31
Cytoband	15q22.2	VPS13C RORA	1.59e-03	29	93	2	15q22.2
Cytoband	21q22.2	SYNJ1 DOP1B	2.06e-03	33	93	2	21q22.2
Cytoband	16q24.1	KIAA0513 CIBAR2	2.06e-03	33	93	2	16q24.1
GeneFamily	Olfactory receptors, family 52	OR52I2 OR52I1 OR52N2 OR52N4 OR52P1 OR52N1 OR52B6 OR52E2	2.35e-11	49	75	8	165
GeneFamily	Olfactory receptors, family 4	OR4S1 OR4A8 OR4A47 OR4E2 OR4E1 OR4C45	1.58e-05	129	75	6	151
GeneFamily	G protein-coupled receptors, Class A orphans	CMKLR2 GPR3 GPR32 GPR173 GPR85	1.79e-05	78	75	5	262
GeneFamily	Olfactory receptors, family 12	OR12D2 OR12D1	5.08e-05	3	75	2	160
GeneFamily	CD molecules\|Membrane spanning 4-domains	MS4A12 MS4A15	2.49e-03	18	75	2	958
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GPR3 LIPG DOCK9 ANO5 ATP8B1 PDE10A	1.26e-06	166	92	6	f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue-Rectum_normal_tissue-6\|TCGA-Colorectal / Sample_Type by Project: Shred V9	PCSK2 DPP6 RSPO2 MS4A12 ANO5 PLP1	1.35e-06	168	92	6	5ce3129a023a48a3d7e6b9306c1fc5addfef9675
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal\|TCGA-Colorectal / Sample_Type by Project: Shred V9	PCSK2 NPY2R RSPO2 MS4A12 ANO5 PLP1	2.09e-06	181	92	6	88f6f56f5f58b479d5db91b32c45934c045f88ea
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	ABCC1 DPP6 LIPG DOCK9 RORA	1.81e-05	156	92	5	1545169694f686d28648a68b552c2ae606599d66
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	OR51E2 PCSK2 OR52N4 ST7L BIRC6	2.51e-05	167	92	5	063ec29b32e40aaa138a691da3a79ee8eef0c2be
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue\|TCGA-Colorectal / Sample_Type by Project: Shred V9	PCSK2 DPP6 RSPO2 ANO5 PLP1	2.66e-05	169	92	5	41cb92b0558f0d5a3e511058efd9110258b88ee3
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue-Rectum_normal_tissue\|TCGA-Colorectal / Sample_Type by Project: Shred V9	PCSK2 DPP6 RSPO2 ANO5 PLP1	2.66e-05	169	92	5	91f4b6a14708e701b2af22989004282041777491
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPP6 S100B SLC22A23 BIRC6 PLP1	3.14e-05	175	92	5	a5db428b078938627e61b7e944c1e0c1d61ac2da
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DPP6 S100B SLC22A23 BIRC6 PLP1	3.14e-05	175	92	5	8b498eea1ec1c1f27b171025c3d08adf3687bafc
ToppCell	RA-16._Neuronal\|RA / Chamber and Cluster_Paper	PCSK2 S100B SLC22A23 PAQR8 PLP1	3.60e-05	180	92	5	5842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	S100B SCD TMC6 PLP1 LLCFC1	3.79e-05	182	92	5	d524ad5cf00f05ee27c9db2ffa2d4e30a1e2e21a
ToppCell	Serous\|World / shred by cell class for bronchial biopsy	S100B PLA2R1 MS4A12 ANO5 PDE10A	3.99e-05	184	92	5	09d0d1525c11dd326efd942684c03f79d992cf3b
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-Like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TMPPE S100B TRIML2 LRRC52	4.16e-05	93	92	4	93a8d3ad978e4cd450f7a69a4cbac1a59038e80d
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	S100B SCD TMC6 TAS2R39 PLP1	4.65e-05	190	92	5	396b7225c2430db3dc55a3d0db70239b71987229
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Macroglial-Astrocyte\|3m / Sample Type, Dataset, Time_group, and Cell type.	S100B LIPG PAQR8 RSPO2 PLP1	5.93e-05	200	92	5	98d7f577b31a603bf835bf9b4ea31999445cf0e5
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Macroglial\|6m / Sample Type, Dataset, Time_group, and Cell type.	S100B TKT SCD PAQR8 PLP1	5.93e-05	200	92	5	42dc8ed66a021097e703eef2d756607396ca2f56
Disease	demyelinating disease (implicated_via_orthology)	S100B PLP1	1.19e-04	6	84	2	DOID:3213 (implicated_via_orthology)
Disease	morbid obesity (is_implicated_in)	NPY2R MC4R	2.22e-04	8	84	2	DOID:11981 (is_implicated_in)
Disease	polycystic ovary syndrome, type 2 diabetes mellitus	MC4R SLC38A11	3.55e-04	10	84	2	EFO_0000660, MONDO_0005148
Disease	HDL cholesterol change measurement, physical activity	LIPG MC4R STARD3	7.46e-04	62	84	3	EFO_0003940, EFO_0007805
Disease	Down syndrome (implicated_via_orthology)	SYNJ1 DOP1B	8.21e-04	15	84	2	DOID:14250 (implicated_via_orthology)
Disease	erythritol measurement	TKT MAST2	1.06e-03	17	84	2	EFO_0021171
Disease	depressive disorder (implicated_via_orthology)	NPY2R PLP1	1.78e-03	22	84	2	DOID:1596 (implicated_via_orthology)
Disease	platelet reactivity measurement, response to clopidogrel	SYNJ1 PDE10A	1.95e-03	23	84	2	EFO_0004985, GO_1903493
Disease	low density lipoprotein cholesterol measurement, response to escitalopram, response to citalopram	DPP6 TRIML2	2.12e-03	24	84	2	EFO_0004611, EFO_0006329, EFO_0007871
Disease	paracentral lobule volume measurement	DOCK9 CARD6	2.30e-03	25	84	2	EFO_0010317
Disease	IGF-1 measurement	IFT140 CCDC47 VPS13C PDE10A OR5D13 DOP1B	2.72e-03	488	84	6	EFO_0004627

Protein segments in the cluster

Peptide	Gene	Start	Entry
FFCDFVTIEMVFHAK	CIBAR2	181	Q6ZTR7
TEMLFFAAVVGLACF	ANO5	311	Q75V66
SMDFTCHADLLLFVC	BIRC6	2341	Q9NR09
VSTVCFFHLALADFM	GPR32	76	O75388
FHSPMLAFEFIQFCR	AP5Z1	401	O43299
AHLAVIDALMAAFAF	CAMSAP3	136	Q9P1Y5
QFFFLLAVCHTVMVD	ATP8B1	526	O43520
IFTVFHIIAMCSTFA	NPY2R	306	P49146
FFLIFAIAECHMLAV	OR8G2P	116	Q6IF36
SFAVVLFECHQMDDF	KIAA0513	161	O60268
SAVISAFFECLRFIM	LTN1	406	O94822
FEACLTQMFFIHNFT	OR52E2	96	Q8NGJ4
ACAAQLAFFLMFIIS	OR8K5	96	Q8NH50
FDECLVQMFFTHTFT	OR52N4	96	Q8NGI2
FLLSHLAFMDVCYSS	OR9Q1	61	Q8NGQ5
NFTAAFAMLATLLCA	MYADML2	86	A6NDP7
FLDPAFFQMDTSCVH	DOP1B	1976	Q9Y3R5
MKAFHTFCVVLLVFG	CCDC47	1	Q96A33
SFQSCMAQLFIEHIF	OR4A47	91	Q6IF82
GCMTQLFTEHFFAAA	OR4C45	91	A6NMZ5
ISFEACLTQMFFIHA	OR51E2	91	Q9H255
FLFIHSAVLLAMAFD	OR52B6	126	Q8NGF0
FESREMQHTCFVVFF	OR4S1	16	Q8NGB4
MQHTCFVVFFLFHVL	OR4S1	21	Q8NGB4
FKMFAVFCALALHCA	PDE10A	401	Q9Y233
DCSFNMTAKTFFIIH	LIPG	76	Q9Y5X9
SFLDFAIFLIVFHMD	LRRC52	191	Q8N7C0
VLAAASHFFNLMFTT	KLHL7	61	Q8IXQ5
ALSTCASHFMVVILF	OR12D2	236	P58182
HMCSIVITYVAAFFT	OR52N2	246	Q8NGI0
ASACLAQMFFIHAFC	OR52P1	96	Q8NH57
HFAAVFCIGSAEMSL	GPR3	96	P46089
LTHFRRVFMDTFCFF	NSUN4	341	Q96CB9
FFHFLGSTEAMLLAV	OR12D1	101	P0DN82
YAIHCFVAMESSTFV	OR56B2P	111	Q8NGI1
AFFATVECVLLAAMA	OR5P2	101	Q8WZ92
EQTFIAHVMAFAACL	ALPP	476	P05187
HMACLSFFFLAACSA	PAQR8	321	Q8TEZ7
LSFCTEMEIPHFFCD	OR7C1	166	O76099
LMSVKGCFTDFHIDF	KDM2B	231	Q8NHM5
LMEVSSAVFFFTDCL	CARD6	546	Q9BX69
LMDFFTISEVCLHQF	DOCK9	1331	Q9BZ29
VSTVCFFHLALADFM	GPR32P1	76	Q8NGA4
VLEFFTAVIAMHFGC	MS4A15	181	Q8N5U1
CKIVAFMAVLFCFHA	GPR173	96	Q9NS66
FCFHAAFMLFCISVT	GPR173	106	Q9NS66
FVVSMFCSFDTKRHL	MAST2	571	Q6P0Q8
HSPMYFFICSLAVAD	MC4R	76	P32245
GVLSCFHTAFMLFCI	GPR85	101	P60893
FHTAFMLFCISVTRY	GPR85	106	P60893
HSFHLSFCFSLASVM	LLCFC1	86	Q96L11
ASFSHSMDFFLLKCE	DPP6	541	P42658
HMSIVISVFICIFFA	SLC38A11	201	Q08AI6
ATRDAMLHFSFFVTI	IFT140	771	Q96RY7
AFCMFATHFHELTAL	MSH2	776	P43246
SCTNTHFLELMAFFL	OR6C75	186	A6NL08
MCFFLSHLSLTDFCF	OR5D13	61	Q8NGL4
HFFCDMSALLKLAFS	OR1E1	176	P30953
ISFSACFTQMFFVHL	OR52I1	96	Q8NGK6
CFTQMFFVHLATAVE	OR52I1	101	Q8NGK6
SISFSACFTQMFFVH	OR52I2	121	Q8NH67
ACFTQMFFVHLATAV	OR52I2	126	Q8NH67
FICSSHFIMVILFFV	OR4A8	236	P0C604
FKACLAQMFFVHTFT	OR52N1	96	Q8NH53
FLSIFLFMCNHVSAL	ABCC1	976	P33527
LMIFSLLEFFVACAT	MS4A12	206	Q9NXJ0
VFISFSHSMFCINIC	TAS2R39	166	P59534
MLFHTTSLCFVCSHF	SYNJ1	676	O43426
DFIICVEMFFAALAL	TMEM184B	296	Q9Y519
VEMFFAALALRHAFT	TMEM184B	301	Q9Y519
FSIAFSIVGMFASHA	SLC22A23	536	A1A5C7
FCHFTTHLEDFAIAM	MICU2	321	Q8IYU8
AFVAMVTTACHEFFE	S100B	76	P04271
PHAFASAIFFMCLFS	TAP2	186	Q03519
FSFALIILNCMDYSH	RSPO2	6	Q6UXX9
TVLDSMSFEAAHEFC	PLA2R1	1266	Q13018
MVFLISFISSVFCGH	SLC47A1	51	Q96FL8
QSLAATMFEFAFHLR	STARD3	421	Q14849
AMHFIFTIFSRVLAF	BRS3	306	P32247
CVAVTVAMHFLFLVA	ADGRD2	721	Q7Z7M1
MFASVFFLTVISLDH	CMKLR2	121	P46091
VTEMSLIYNFSHCAF	TRIML2	386	Q8N7C3
ISFDACVTQMFFLHL	OR4E1	96	P0C645
CVTQMFFLHLFACTE	OR4E1	101	P0C645
ALSTCSAHFMVVALF	OR4E2	236	Q8NGC2
CCSAAEIMAVLFFHT	TKT	41	P29401
SFVFEFGKSLCSMHL	RORA	401	P35398
FHQALFTCLFMSPVE	ZNF654	231	Q8IZM8
LFIHFTAGFCSSTAM	ST7L	511	Q8TDW4
CASVEFLMTVADFFI	VPS13C	2051	Q709C8
HINFTTFFIDCMAAL	SCD	316	O00767
PCLMEASAAAVFSHF	SLC9B1	191	Q4ZJI4
CLGLISDSFHMFFDS	SLC30A7	61	Q8NEW0
LGCAVAVHVFSEFMI	TMC6	446	Q7Z403
CFMQSVFDHFPEILF	ZSWIM1	66	Q9BR11
HLLITAAVCVFFTAM	PIGG	961	Q5H8A4
VLHMCSLFHAFIFAQ	UNC79	2466	Q9P2D8
AHSSFFTMFFLVAEE	TMPPE	96	Q6ZT21
HLSFQEFFAAMSFVL	NLRP13	536	Q86W25
SICKTAEFQMTFHLF	PLP1	226	P60201
AAAGFLFCVMVFASA	PCSK2	11	P16519