Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	semicircular canal development	GLI3 FGF10 CHD7	1.21e-05	11	88	3	GO:0060872
GeneOntologyBiologicalProcess	pattern specification process	SOX1 BMP7 SFRP2 GLI3 PLD6 FGF10 GATA5 IRX1 DISP1 FOXC1 DOP1B	1.45e-05	526	88	11	GO:0007389
GeneOntologyBiologicalProcess	embryonic pattern specification	BMP7 PLD6 FGF10 DISP1 DOP1B	4.39e-05	91	88	5	GO:0009880
GeneOntologyBiologicalProcess	digestive system development	SFRP2 IGF1R GLI3 ASS1 FGF10 GATA5	8.06e-05	167	88	6	GO:0055123
GeneOntologyBiologicalProcess	odontogenesis of dentin-containing tooth	BMP7 GLI3 FGF10 KLK5 FOXC1	9.52e-05	107	88	5	GO:0042475
GeneOntologyBiologicalProcess	exocrine system development	BMP7 IGF1R FGF10 FOXC1	1.03e-04	57	88	4	GO:0035272
GeneOntologyBiologicalProcess	mammary gland specification	GLI3 FGF10	1.07e-04	4	88	2	GO:0060594
GeneOntologyCellularComponent	epidermal lamellar body	KLK5 SPINK5	1.14e-04	4	92	2	GO:0097209
MousePheno	abnormal semicircular canal morphology	BMP7 IGF1R SLC12A2 GLI3 FGF10 CHD7	4.25e-07	59	69	6	MP:0002428
MousePheno	abnormal inner ear canal morphology	BMP7 IGF1R SLC12A2 GLI3 FGF10 CHD7	6.31e-07	63	69	6	MP:0002729
MousePheno	abnormal basicranium morphology	BMP7 IGF1R GLI3 CHD7 DISP1 PRRC2B FOXC1	2.36e-06	123	69	7	MP:0010029
MousePheno	abnormal lateral semicircular canal morphology	IGF1R GLI3 FGF10 CHD7	3.05e-06	21	69	4	MP:0000037
MousePheno	abnormal vibrissa number	BMP7 GLI3 FOXC1	6.33e-06	8	69	3	MP:0009003
MousePheno	absent epiglottis	GLI3 FOXC1	2.40e-05	2	69	2	MP:0013261
MousePheno	abnormal craniofacial development	BMP7 CDK13 GLI3 FGF10 CHD7 IRX1 REV3L DISP1 PRRC2B FOXC1	4.15e-05	425	69	10	MP:0003935
MousePheno	abnormal nose morphology	BMP7 CDK13 GLI3 FGF10 CHD7 DISP1 FOXC1	5.81e-05	201	69	7	MP:0002233
MousePheno	abnormal superior semicircular canal morphology	GLI3 FGF10 CHD7	6.16e-05	16	69	3	MP:0003069
MousePheno	small basisphenoid bone	BMP7 GLI3 FOXC1	6.16e-05	16	69	3	MP:0004462
MousePheno	abnormal limb development	BMP7 SFRP2 GLI3 FGF10 CHD7 VCL	6.47e-05	140	69	6	MP:0006279
MousePheno	abnormal posterior semicircular canal morphology	IGF1R FGF10 CHD7	1.24e-04	20	69	3	MP:0002858
MousePheno	neonatal lethality	FLNC BMP7 IGF1R CELSR3 GLI3 ASS1 LAMA4 FGF10 IRX1 DISP1 NR1D2 FOXC1 SPINK5	1.24e-04	799	69	13	MP:0002058
MousePheno	abnormal otic capsule morphology	GLI3 FGF10 CHD7	1.44e-04	21	69	3	MP:0000039
MousePheno	abnormal basisphenoid bone morphology	BMP7 GLI3 DISP1 FOXC1	1.76e-04	57	69	4	MP:0000106
MousePheno	abnormal digit development	SFRP2 GLI3 CHD7	1.90e-04	23	69	3	MP:0006280
MousePheno	abnormal KLRG1+ CD8 alpha-beta T cell number	BACH2 GMDS	2.38e-04	5	69	2	MP:0013153
MousePheno	aortic arch coarctation	CHD7 FOXC1	2.38e-04	5	69	2	MP:0010526
MousePheno	abnormal Harderian gland size	GLI3 FGF10	2.38e-04	5	69	2	MP:0013442
MousePheno	abnormal nasal cartilage morphology	BMP7 GLI3 FOXC1	2.45e-04	25	69	3	MP:0031449
MousePheno	neonatal lethality, complete penetrance	FLNC IGF1R CELSR3 GLI3 ASS1 FGF10 IRX1 DISP1 FOXC1 SPINK5	2.72e-04	534	69	10	MP:0011087
MousePheno	abnormal hard palate morphology	BMP7 GLI3 FGF10 CHD7	3.30e-04	67	69	4	MP:0003756
MousePheno	abnormal crista ampullaris morphology	SLC12A2 FGF10 CHD7	3.45e-04	28	69	3	MP:0004249
MousePheno	abnormal neurocranium morphology	BMP7 IGF1R GLI3 CHD7 DISP1 PRRC2B FOXC1	3.52e-04	269	69	7	MP:0000074
MousePheno	abnormal clitoris size	CHD7 GATA5	3.56e-04	6	69	2	MP:0009100
MousePheno	absent pituitary gland	FGF10 DISP1	3.56e-04	6	69	2	MP:0005315
MousePheno	abnormal laryngeal cartilage morphology	BMP7 GLI3 FOXC1	3.84e-04	29	69	3	MP:0002256
MousePheno	abnormal secretory circumventricular organ morphology	GLI3 FGF10 CHD7	3.84e-04	29	69	3	MP:0013563
MousePheno	abnormal cochlear inner hair cell number	IGF1R SLC12A2 CHD7	4.25e-04	30	69	3	MP:0004394
MousePheno	abnormal circumventricular organ morphology	GLI3 FGF10 CHD7	4.69e-04	31	69	3	MP:0013562
MousePheno	failure of endochondral bone ossification	GLI3 FOXC1	4.96e-04	7	69	2	MP:0008275
MousePheno	decreased lateral semicircular canal size	FGF10 CHD7	4.96e-04	7	69	2	MP:0003162
MousePheno	abnormal throat morphology	GLI3 FOXC1	4.96e-04	7	69	2	MP:0010370
MousePheno	abnormal epiglottis morphology	GLI3 FOXC1	4.96e-04	7	69	2	MP:0010371
MousePheno	abnormal nasal gland morphology	CDK13 FGF10	4.96e-04	7	69	2	MP:0013580
MousePheno	abnormal pilosebaceous unit morphology	BMP7 IGF1R ASS1 FGF10 GATA5 SPINK5	5.14e-04	205	69	6	MP:0030572
MousePheno	abnormal ectoderm morphology	BMP7 GLI3 FGF10	5.15e-04	32	69	3	MP:0014139
MousePheno	abnormal temporal bone petrous part morphology	BMP7 IGF1R CHD7	5.15e-04	32	69	3	MP:0030319
MousePheno	abnormal semicircular canal ampulla morphology	SLC12A2 FGF10 CHD7	5.15e-04	32	69	3	MP:0008488
MousePheno	abnormal cranial foramen morphology	CHD7 PRRC2B FOXC1	5.65e-04	33	69	3	MP:0030310
MousePheno	sparse vibrissae	HEPHL1 SPINK5	6.60e-04	8	69	2	MP:0001283
MousePheno	abnormal clitoris morphology	CHD7 GATA5	6.60e-04	8	69	2	MP:0003127
MousePheno	ectopic ovary	GLI3 FOXC1	6.60e-04	8	69	2	MP:0011727
MousePheno	abnormal radius morphology	SFRP2 GLI3 FGF10 FOXC1	7.12e-04	82	69	4	MP:0000552
MousePheno	abnormal pituitary diverticulum morphology	FGF10 CHD7 FOXC1	7.31e-04	36	69	3	MP:0003817
MousePheno	abnormal metatarsal bone morphology	SFRP2 GLI3 FOXC1	7.31e-04	36	69	3	MP:0003072
MousePheno	abnormal ulna morphology	SFRP2 GLI3 FGF10 FOXC1	7.79e-04	84	69	4	MP:0005108
MousePheno	abnormal metacarpal bone morphology	SFRP2 GLI3 FOXC1	7.93e-04	37	69	3	MP:0003073
MousePheno	abnormal hair follicle morphology	BMP7 IGF1R ASS1 FGF10 SPINK5	8.10e-04	148	69	5	MP:0000377
MousePheno	decreased Ly6C-positive mature NK cell number	BACH2 GMDS	8.45e-04	9	69	2	MP:0013675
MousePheno	absent upper incisors	BMP7 DISP1	8.45e-04	9	69	2	MP:0004790
MousePheno	absent posterior semicircular canal	FGF10 CHD7	8.45e-04	9	69	2	MP:0003163
MousePheno	absent radius	GLI3 FGF10	8.45e-04	9	69	2	MP:0000553
MousePheno	increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number	BACH2 GMDS	8.45e-04	9	69	2	MP:0013430
MousePheno	increased memory-marker NK cell number	BACH2 GMDS	8.45e-04	9	69	2	MP:0013427
MousePheno	fused tarsal bones	GLI3 FOXC1	8.45e-04	9	69	2	MP:0008919
MousePheno	decreased memory-marker CD4-negative NK T cell number	BACH2 GMDS	8.45e-04	9	69	2	MP:0013513
MousePheno	abnormal adenohypophysis development	FGF10 CHD7 FOXC1	8.58e-04	38	69	3	MP:0013337
MousePheno	short radius	SFRP2 GLI3 FOXC1	9.98e-04	40	69	3	MP:0004355
MousePheno	abnormal larynx morphology	BMP7 GLI3 FOXC1	9.98e-04	40	69	3	MP:0002249
MousePheno	abnormal scapula morphology	FGF10 CHD7 FOXC1	9.98e-04	40	69	3	MP:0000149
MousePheno	decreased radius size	SFRP2 GLI3 FOXC1	9.98e-04	40	69	3	MP:0030886
MousePheno	abnormal neuroendocrine gland morphology	GLI3 FGF10 CHD7 DISP1 FOXC1	1.03e-03	156	69	5	MP:0000631
MousePheno	abnormal limb bud morphology	BMP7 GLI3 FGF10 VCL	1.05e-03	91	69	4	MP:0005650
MousePheno	abnormal ovary topology	GLI3 FOXC1	1.05e-03	10	69	2	MP:0020491
MousePheno	abnormal memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number	BACH2 GMDS	1.05e-03	10	69	2	MP:0013428
MousePheno	abnormal mammary gland embryonic development	GLI3 FGF10	1.05e-03	10	69	2	MP:0004135
MousePheno	decreased CD4-negative NK T cell number	BACH2 GMDS	1.05e-03	10	69	2	MP:0013510
MousePheno	abnormal secondary palate morphology	BMP7 CDK13 GLI3 FGF10 CHD7	1.12e-03	159	69	5	MP:0013550
MousePheno	abnormal kidney development	BMP7 CDK13 FGF10 FOXC1	1.14e-03	93	69	4	MP:0000527
MousePheno	abnormal pituitary gland development	FGF10 CHD7 FOXC1	1.15e-03	42	69	3	MP:0003816
MousePheno	abnormal occipital bone morphology	BMP7 DISP1 PRRC2B FOXC1	1.23e-03	95	69	4	MP:0005269
MousePheno	abnormal sphenoid bone morphology	BMP7 GLI3 DISP1 FOXC1	1.23e-03	95	69	4	MP:0000104
MousePheno	abnormal heart valve morphology	GATA5 VCL PRRC2B NR1D2 FOXC1	1.25e-03	163	69	5	MP:0000285
MousePheno	absent neurocranium	GLI3 FOXC1	1.28e-03	11	69	2	MP:0000075
MousePheno	decreased myocardial fiber number	GATA5 VCL	1.28e-03	11	69	2	MP:0004567
MousePheno	abnormal cerebellum development	GLI3 ASS1 CHD7 FOXC1	1.28e-03	96	69	4	MP:0000854
MousePheno	respiratory failure	FLNC IGF1R CELSR3 IRX1 FOXC1	1.32e-03	165	69	5	MP:0001953
MousePheno	increased NK T cell number	BACH2 GMDS CHD7	1.32e-03	44	69	3	MP:0008039
MousePheno	abnormal respiratory system physiology	FLNC IGF1R CELSR3 GLI3 BACH2 FGF10 CHD7 IRX1 RGS3 DISP1 FOXC1 CA6	1.34e-03	897	69	12	MP:0002133
MousePheno	abnormal xiphoid process morphology	BMP7 GLI3 FOXC1	1.41e-03	45	69	3	MP:0000159
MousePheno	trunk curl	PHYH NRXN2 CHD7	1.41e-03	45	69	3	MP:0001512
MousePheno	abnormal hyaline cartilage morphology	BMP7 GLI3 FOXC1	1.50e-03	46	69	3	MP:0006429
MousePheno	short ulna	SFRP2 GLI3 FOXC1	1.50e-03	46	69	3	MP:0004359
MousePheno	decreased ulna size	SFRP2 GLI3 FOXC1	1.50e-03	46	69	3	MP:0030900
MousePheno	decreased respiration	FLNC IGF1R CELSR3 IRX1 FOXC1	1.50e-03	170	69	5	MP:0014274
MousePheno	abnormal bony labyrinth	IGF1R CHD7	1.53e-03	12	69	2	MP:0004289
MousePheno	abnormal Ly6C-positive mature NK cell number	BACH2 GMDS	1.53e-03	12	69	2	MP:0013674
MousePheno	abnormal palatal rugae morphology	FGF10 CHD7	1.53e-03	12	69	2	MP:0009652
MousePheno	abnormal memory-marker NK cell number	BACH2 GMDS	1.53e-03	12	69	2	MP:0013425
MousePheno	abnormal pharyngeal arch morphology	GLI3 CHD7 DISP1 PRRC2B FOXC1	1.54e-03	171	69	5	MP:0002884
MousePheno	abnormal pharyngeal arch artery morphology	CHD7 PRRC2B FOXC1	1.60e-03	47	69	3	MP:0002672
MousePheno	abnormal nasal septum morphology	BMP7 GLI3 DISP1	1.60e-03	47	69	3	MP:0002239
MousePheno	abnormal forelimb zeugopod morphology	SFRP2 GLI3 FGF10 FOXC1	1.61e-03	102	69	4	MP:0003855
MousePheno	abnormal choroid plexus morphology	MANBA GLI3 FOXC1	1.70e-03	48	69	3	MP:0000820
MousePheno	abnormal tela choroidea morphology	MANBA GLI3 FOXC1	1.70e-03	48	69	3	MP:0013306
MousePheno	aorta coarctation	CHD7 FOXC1	1.81e-03	13	69	2	MP:0003387
MousePheno	abnormal lens vesicle development	SOX1 BMP7	1.81e-03	13	69	2	MP:0001292
MousePheno	abnormal nasal mucosa morphology	CDK13 FGF10	1.81e-03	13	69	2	MP:0002238
MousePheno	absent lateral semicircular canal	GLI3 CHD7	1.81e-03	13	69	2	MP:0003161
Domain	Laminin_G_2	NELL2 CELSR3 NRXN2 LAMA4	4.21e-05	40	91	4	PF02210
Domain	LamG	NELL2 CELSR3 NRXN2 LAMA4	6.17e-05	44	91	4	SM00282
Domain	Laminin_G	NELL2 CELSR3 NRXN2 LAMA4	1.83e-04	58	91	4	IPR001791
Domain	Sel1	SEL1L SEL1L2	6.45e-04	8	91	2	PF08238
Domain	SEL1	SEL1L SEL1L2	6.45e-04	8	91	2	SM00671
Domain	Sel1-like	SEL1L SEL1L2	8.27e-04	9	91	2	IPR006597
Domain	LAM_G_DOMAIN	CELSR3 NRXN2 LAMA4	8.34e-04	38	91	3	PS50025
Domain	-	NELL2 CELSR3 NRXN2 LAMA4	1.20e-03	95	91	4	2.60.120.200
Domain	CarboxyPept_regulatory_dom	CPD CPE	1.77e-03	13	91	2	IPR014766
Domain	-	CPD CPE	1.77e-03	13	91	2	2.60.40.1120
Domain	MORN	MORN1 RSPH10B	2.06e-03	14	91	2	SM00698
Domain	MORN	MORN1 RSPH10B	2.37e-03	15	91	2	IPR003409
Domain	MORN	MORN1 RSPH10B	2.37e-03	15	91	2	PF02493
Domain	CarboxyPept-like_regulatory	CPD CPE	3.04e-03	17	91	2	IPR008969
Domain	Zn_pept	CPD CPE	3.41e-03	18	91	2	SM00631
Domain	CARBOXYPEPT_ZN_2	CPD CPE	3.80e-03	19	91	2	PS00133
Domain	CARBOXYPEPT_ZN_1	CPD CPE	4.21e-03	20	91	2	PS00132
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	SEL1L DCAF1 USP34 FLNC FAM120A PTPRD FLAD1 CCT8 CPD SDHA VCL PRRC2B VCPIP1	1.74e-06	974	92	13	28675297
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	HAUS6 SLC12A2 GLI3 TENM1 CPD PRRC2B VCPIP1	6.62e-06	263	92	7	34702444
Pubmed	Identification of a region within SEL1L protein required for tumour growth inhibition.	SEL1L SEL1L2	6.92e-06	2	92	2	14729273
Pubmed	Differential regulation and localization of carboxypeptidase D and carboxypeptidase E in human and mouse β-cells.	CPD CPE	6.92e-06	2	92	2	21628999
Pubmed	Combined detection of plasma GATA5 and SFRP2 methylation is a valid noninvasive biomarker for colorectal cancer and adenomas.	SFRP2 GATA5	6.92e-06	2	92	2	25759530
Pubmed	KLK5 Inactivation Reverses Cutaneous Hallmarks of Netherton Syndrome.	KLK5 SPINK5	6.92e-06	2	92	2	26390218
Pubmed	Immunohistochemical localization of carboxypeptidases E and D in the human placenta and umbilical cord.	CPD CPE	6.92e-06	2	92	2	9815277
Pubmed	A lipid-regulated docking site on vinculin for protein kinase C.	PRKCA VCL	6.92e-06	2	92	2	11741957
Pubmed	Disruptions in a cluster of computationally identified enhancers near FOXC1 and GMDS may influence brain development.	GMDS FOXC1	6.92e-06	2	92	2	26382291
Pubmed	[Expression and significance of IGF-IR and PKC in laryngeal squamous cell carcinoma].	IGF1R PRKCA	6.92e-06	2	92	2	20422977
Pubmed	The IGF-I receptor can alter the matrix metalloproteinase repertoire of tumor cells through transcriptional regulation of PKC-{alpha}.	IGF1R PRKCA	6.92e-06	2	92	2	19855090
Pubmed	Pitx1 and Pitx2 are required for development of hindlimb buds.	BMP7 GLI3 FGF10	1.42e-05	18	92	3	12441290
Pubmed	Forkhead transcription factors, Foxc1 and Foxc2, are required for the morphogenesis of the cardiac outflow tract.	BMP7 FGF10 FOXC1	1.42e-05	18	92	3	16839542
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	HAUS6 FAM120A ACACA FARP1 BACH2 CCT8 PRKCA CPD VCL PRRC2B VCPIP1	1.60e-05	853	92	11	28718761
Pubmed	Syndactyly of Ft/+ mice correlates with an imbalance in bmp4 and fgf8 expression.	BMP7 GLI3 FGF10	1.98e-05	20	92	3	10534616
Pubmed	Dichotomous effect of ultraviolet B on the expression of corneodesmosomal enzymes in human epidermal keratinocytes.	KLK5 SPINK5	2.07e-05	3	92	2	19118981
Pubmed	Cathelicidin represents a new target for manipulation of skin inflammation in Netherton syndrome.	KLK5 SPINK5	2.07e-05	3	92	2	32442469
Pubmed	Immunohistochemical localization of carboxypeptidases D, E, and Z in pituitary adenomas and normal human pituitary.	CPD CPE	2.07e-05	3	92	2	12417617
Pubmed	The F-actin cross-linking and focal adhesion protein filamin A is a ligand and in vivo substrate for protein kinase C alpha.	FLNC PRKCA	2.07e-05	3	92	2	12704190
Pubmed	Identification of a Z-band associated protein complex involving KY, FLNC and IGFN1.	FLNC IGFN1	2.07e-05	3	92	2	20206623
Pubmed	Overexpression of insulin-like growth factor 1 receptor and frequent mutational inactivation of SDHA in wild-type SDHB-negative gastrointestinal stromal tumors.	IGF1R SDHA	2.07e-05	3	92	2	23109135
Pubmed	LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum.	KLK5 SPINK5	2.07e-05	3	92	2	15675955
Pubmed	Carboxypeptidase E in the mouse placenta.	CPD CPE	2.07e-05	3	92	2	17177860
Pubmed	CDK13 promotes lipid deposition and prostate cancer progression by stimulating NSUN5-mediated m5C modification of ACC1 mRNA.	ACACA CDK13	2.07e-05	3	92	2	37845385
Pubmed	Genome-wide association study identifies kallikrein 5 in type 2 inflammation-low asthma.	KLK5 SPINK5	2.07e-05	3	92	2	35487308
Pubmed	Growth arrest specific gene 1 acts as a region-specific mediator of the Fgf10/Fgf8 regulatory loop in the limb.	BMP7 GLI3 FGF10	2.30e-05	21	92	3	12399319
Pubmed	The Isl1/Ldb1 Complex Orchestrates Genome-wide Chromatin Organization to Instruct Differentiation of Multipotent Cardiac Progenitors.	FGF10 IRX1 FOXC1	3.05e-05	23	92	3	26321200
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	USP34 FLNC IGF1R CELSR3 ACACA MORN1 CDK13 JOSD1 REV3L CYB5R2 SDHA PRRC2B	3.49e-05	1105	92	12	35748872
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	SEL1L IGF1R MANBA ACACA ASS1 CCT8 CPD COPS3 SDHA	3.67e-05	613	92	9	22268729
Pubmed	Multistep phosphorylation by oncogenic kinases enhances the degradation of the NF2 tumor suppressor merlin.	DCAF1 PRKCA	4.14e-05	4	92	2	21750658
Pubmed	Frequent concomitant epigenetic silencing of SOX1 and secreted frizzled-related proteins (SFRPs) in human hepatocellular carcinoma.	SOX1 SFRP2	4.14e-05	4	92	2	23215838
Pubmed	Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin.	KLK5 SPINK5	4.14e-05	4	92	2	17012259
Pubmed	Fine-scale haplotype mapping of MUT, AACS, SLC6A15 and PRKCA genes indicates association with insulin resistance of metabolic syndrome and relationship with branched chain amino acid metabolism or regulation.	AACS PRKCA	4.14e-05	4	92	2	30913280
Pubmed	FGFR2, FGF8, FGF10 and BMP7 as candidate genes for hypospadias.	BMP7 FGF10	4.14e-05	4	92	2	17264867
Pubmed	Involvement of FGF and BMP family proteins and VEGF in early human kidney development.	BMP7 FGF10	4.14e-05	4	92	2	18437684
Pubmed	Genetic modifiers interact with Cpe(fat) to affect body weight, adiposity, and hyperglycemia.	CPD CPE	4.14e-05	4	92	2	15870393
Pubmed	GATA6 is a crucial regulator of Shh in the limb bud.	BMP7 GLI3 GATA5	4.46e-05	26	92	3	24415953
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	DCAF1 HAUS6 ACACA PRKCA PRRC2B VCPIP1	4.62e-05	242	92	6	34011540
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TPP2 USP34 FLNC FAM120A ACACA CHD7 SDHA VCL PRRC2B	5.97e-05	653	92	9	22586326
Pubmed	Filamin C interacts with the muscular dystrophy KY protein and is abnormally distributed in mouse KY deficient muscle fibres.	FLNC IGFN1	6.89e-05	5	92	2	15385448
Pubmed	Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing.	GLI3 PRKCA	6.89e-05	5	92	2	16371461
Pubmed	Bmp7 regulates branching morphogenesis of the lacrimal gland by promoting mesenchymal proliferation and condensation.	BMP7 FGF10	6.89e-05	5	92	2	15280212
Pubmed	Etiology of esophageal atresia and tracheoesophageal fistula: "mind the gap".	GLI3 CHD7	6.89e-05	5	92	2	20425471
Pubmed	Polymorphic markers associated with severe oxaliplatin-induced, chronic peripheral neuropathy in colon cancer patients.	GMDS FOXC1	6.89e-05	5	92	2	22020760
Pubmed	The interaction of the bisphosphorylated N-terminal arm of cardiac troponin I-A 31P-NMR study.	PRKCA TNNT1	6.89e-05	5	92	2	11904166
Pubmed	Expression pattern of Irx1 and Irx2 during mouse digit development.	GLI3 IRX1	6.89e-05	5	92	2	11472848
Pubmed	Tbx1 is required autonomously for cell survival and fate in the pharyngeal core mesoderm to form the muscles of mastication.	FGF10 GATA5 FOXC1	9.23e-05	33	92	3	24705356
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	ACACA CDK13 FARP1 CCT8 COPS3 GTF3C4 VCL	9.41e-05	399	92	7	37536630
Pubmed	BMP7 acts in murine lens placode development.	BMP7 SFRP2	1.03e-04	6	92	2	10049573
Pubmed	Pax6 is required for delta-catenin/neurojugin expression during retinal, cerebellar and cortical development in mice.	SFRP2 VCL	1.03e-04	6	92	2	16973151
Pubmed	Pleiotropy in FOXC1-attributable phenotypes involves altered ciliation and cilia-dependent signaling.	GLI3 FOXC1	1.03e-04	6	92	2	39217245
Pubmed	Gli3-mediated somitic Fgf10 expression gradients are required for the induction and patterning of mammary epithelium along the embryonic axes.	GLI3 FGF10	1.03e-04	6	92	2	16720875
Pubmed	Irx1 and Irx2 expression in early lung development.	GLI3 IRX1	1.03e-04	6	92	2	11472847
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	SEL1L PLBD1 UPB1 PTPRD GOLM2 BACH2 APOOL GMDS CHD7 KLK5 PRRC2B DOP1B	1.06e-04	1242	92	12	30973865
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	DCAF1 USP34 GLI3 CHD7 COPS3 FOXC1	1.07e-04	282	92	6	23667531
Pubmed	Proteome analysis of the circadian clock protein PERIOD2.	FLNC ACACA CCT8 PRKCA	1.17e-04	94	92	4	35122331
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	DTD1 TPP2 USP34 FLNC ACACA ASS1 CCT8 GMDS COPS3 EIF3J GTF3C4 VCL VCPIP1	1.18e-04	1455	92	13	22863883
Pubmed	Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy.	PRKCA TNNT1 VCL	1.20e-04	36	92	3	23236519
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	USP34 HAUS6 ACACA CCT8 CHD7 GTF3C4 VCPIP1	1.25e-04	418	92	7	34709266
Pubmed	A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.	DCAF1 DCAF8L1 COPS3	1.30e-04	37	92	3	16949367
Pubmed	GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis.	BMP7 GLI3 FGF10	1.30e-04	37	92	3	22465667
Pubmed	Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).	PLBD1 FARP1 TENM1	1.41e-04	38	92	3	22952603
Pubmed	BMP7 and SHH regulate Pax2 in mouse retinal astrocytes by relieving TLX repression.	BMP7 GLI3	1.44e-04	7	92	2	19505455
Pubmed	Impaired meningeal development in association with apical expansion of calvarial bone osteogenesis in the Foxc1 mutant.	BMP7 FOXC1	1.44e-04	7	92	2	18422524
Pubmed	Difference in apical and basal growth of the frontal bone primordium in Foxc1ch/ch mice.	BMP7 FOXC1	1.44e-04	7	92	2	24417671
Pubmed	Sox2 and Pou2f1 interact to control lens and olfactory placode development.	BMP7 SFRP2	1.44e-04	7	92	2	17140559
Pubmed	Novel genetic variants contributing to left ventricular hypertrophy: the HyperGEN study.	SFRP2 CPE	1.44e-04	7	92	2	19593212
Pubmed	Interactions between HOXD and Gli3 genes control the limb apical ectodermal ridge via Fgf10.	GLI3 FGF10	1.44e-04	7	92	2	17467687
Pubmed	Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks.	FLNC CCT8 CHD7 GTF3C4	1.60e-04	102	92	4	26584622
Pubmed	Functional proteomics mapping of a human signaling pathway.	FLNC ZNF41 CDK13 LAMA4 ZNF510 RGS3 VCL VCPIP1	1.77e-04	591	92	8	15231748
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DCAF1 USP34 NELL2 FAM120A GLI3 BACH2 ASS1 REV3L VAV1 PRRC2B FOXC1	1.77e-04	1116	92	11	31753913
Pubmed	Cockayne syndrome group A and ferrochelatase finely tune ribosomal gene transcription and its response to UV irradiation.	CCT8 PRKCA COPS3	1.91e-04	42	92	3	34581821
Pubmed	Morphogenesis.	GLI3 FGF10	1.92e-04	8	92	2	9988217
Pubmed	Requirement of Smad4 from Ocular Surface Ectoderm for Retinal Development.	GLI3 PRKCA	1.92e-04	8	92	2	27494603
Pubmed	A-kinase anchoring protein BIG3 coordinates oestrogen signalling in breast cancer cells.	IGF1R PRKCA	1.92e-04	8	92	2	28555617
Pubmed	Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.	PTPRD NRXN2	1.92e-04	8	92	2	37591863
Pubmed	Patterning events and specification signals in the developing hippocampus.	BMP7 GLI3	1.92e-04	8	92	2	10498273
Pubmed	Enhancer redundancy provides phenotypic robustness in mammalian development.	GLI3 FGF10	1.92e-04	8	92	2	29420474
Pubmed	Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation.	BMP7 GLI3	1.92e-04	8	92	2	12221011
Pubmed	Sonic hedgehog is essential to foregut development.	GLI3 FGF10	1.92e-04	8	92	2	9731532
Pubmed	Global landscape of HIV-human protein complexes.	SEL1L DCAF1 FLAD1 COPS3 EIF3J SDHA FOXC1	2.17e-04	457	92	7	22190034
Pubmed	Exocrine glands and the Chievitz organ of some mouse mutants.	GLI3 FOXC1	2.46e-04	9	92	2	5088022
Pubmed	Cholesterol modification restricts the spread of Shh gradient in the limb bud.	GLI3 DISP1	2.46e-04	9	92	2	16611729
Pubmed	Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning.	SOX1 GLI3	2.46e-04	9	92	2	23249739
Pubmed	Bmp2, Bmp4 and Bmp7 are co-required in the mouse AER for normal digit patterning but not limb outgrowth.	BMP7 FGF10	2.46e-04	9	92	2	22662233
Pubmed	Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities.	GLI3 DISP1	2.46e-04	9	92	2	15315763
Pubmed	Decoupling the function of Hox and Shh in developing limb reveals multiple inputs of Hox genes on limb growth.	GLI3 FGF10	2.46e-04	9	92	2	23633510
Pubmed	Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.	FLNC VCL	2.46e-04	9	92	2	11807098
Pubmed	Wnt signaling inhibitors regulate the transcriptional response to morphogenetic Shh-Gli signaling in the neural tube.	SFRP2 GLI3	2.46e-04	9	92	2	16950124
Pubmed	Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.	SOX1 NRXN2 GLI3 FGF10 CHD7 VCL	2.55e-04	331	92	6	20634891
Pubmed	Negative and positive auto-regulation of BMP expression in early eye development.	BMP7 SFRP2	3.07e-04	10	92	2	26407529
Pubmed	Patched1 patterns Fibroblast growth factor 10 and Forkhead box F1 expression during pulmonary branch formation.	GLI3 FGF10	3.07e-04	10	92	2	28939119
Pubmed	A model for obesity and gigantism due to disruption of the Ankrd26 gene.	IGF1R ANKRD62	3.07e-04	10	92	2	18162531
Pubmed	Fusion of lung lobes and vessels in mouse embryos heterozygous for the forkhead box f1 targeted allele.	GLI3 FGF10	3.07e-04	10	92	2	11943666
Pubmed	Primary cellular meningeal defects cause neocortical dysplasia and dyslamination.	LAMA4 FOXC1	3.07e-04	10	92	2	20976766
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	SEL1L USP34 NELL2 IGF1R MANBA SLC12A2 CELSR3 GOLM2 CCT8 LAMA4 CPD	3.32e-04	1201	92	11	35696571
Pubmed	Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.	DCAF1 ACACA CCT8 EIF3J VCL	3.44e-04	226	92	5	31452512
Pubmed	BMP signals control limb bud interdigital programmed cell death by regulating FGF signaling.	BMP7 FGF10	3.75e-04	11	92	2	17537800
Pubmed	Brachy-syndactyly caused by loss of Sfrp2 function.	BMP7 SFRP2	3.75e-04	11	92	2	18446812
Pubmed	Embryonic origin and remodeling of the urinary and digestive outlets.	BMP7 FGF10	3.75e-04	11	92	2	23390542
Cytoband	6p25	GMDS FOXC1	4.68e-04	16	92	2	6p25
Cytoband	9q34.13	GTF3C4 PRRC2B	8.14e-04	21	92	2	9q34.13
Cytoband	7p13	CDK13 GLI3	2.80e-03	39	92	2	7p13
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_1000	BMP7 SFRP2 ACACA GOLM2 GLI3 BACH2 LAMA4 CPD REV3L PRRC2B	9.12e-07	312	91	10	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000	SEL1L BMP7 SFRP2 ACACA GOLM2 GLI3 BACH2 LAMA4 CPD GATA5 REV3L TNNT1 VCL PRRC2B FOXC1	1.60e-06	806	91	15	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlas	DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#1_top-relative-expression-ranked_200	SEL1L BMP7 GOLM2 REV3L	9.09e-06	31	91	4	gudmap_developingKidney_e15.5_stage III -IV renal corpusc_200_k1
CoexpressionAtlas	DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_top-relative-expression-ranked_1000	SEL1L BMP7 PTPRD SLC12A2 GOLM2 APOOL LAMA4 CPD CHD7 GATA5 IRX1 REV3L RGS3 FOXC1	1.25e-05	837	91	14	gudmap_developingKidney_e15.5_stage III -IV renal corpusc_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#1_top-relative-expression-ranked_1000	BMP7 GOLM2 GLI3 BACH2 LAMA4 CPD REV3L	3.25e-05	209	91	7	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k1
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#2_top-relative-expression-ranked_200	SEL1L GOLM2 LAMA4 CPD REV3L	3.83e-05	88	91	5	gudmap_developingKidney_e15.5_200_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000	BMP7 SFRP2 GOLM2 GLI3 BACH2 LAMA4 CPD GATA5 REV3L	4.08e-05	385	91	9	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000	TPP2 BMP7 SFRP2 GOLM2 LAMA4 CPD REV3L RPE	1.87e-04	369	91	8	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000	BMP7 SFRP2 SLC12A2 CELSR3 NRXN2 GOLM2 GLI3 BACH2 LAMA4 CPD GATA5 REV3L	1.90e-04	818	91	12	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#5_top-relative-expression-ranked_200	GOLM2 BACH2 LAMA4 REV3L	2.21e-04	69	91	4	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_200_k5
CoexpressionAtlas	ECTO blastocyst_vs_ECTO UCB CD34+Z-Confounder_removed-fold2.0_adjp0.05	BMP7 PTPRD SLC12A2 PRKCA CPE IRX1 DISP1	2.21e-04	284	91	7	PCBC_ratio_ECTO blastocyst_vs_ECTO UCB CD34+Z_cfr-2X-p05
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#2_top-relative-expression-ranked_500	GOLM2 BACH2 LAMA4 CPD GATA5 REV3L	2.81e-04	209	91	6	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500_k2
CoexpressionAtlas	DevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#3_top-relative-expression-ranked_500	SEL1L BMP7 GOLM2 CPD	2.89e-04	74	91	4	gudmap_developingKidney_e15.5_S-shaped body_500_k3
ToppCell	3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC12A2 ASS1 GLYATL2 GMDS CYB5R2 FOXC1 MGAM2	1.04e-07	182	92	7	2f7d9c0bf7155ac376e63fc9d9542b5c3ab89f04
ToppCell	3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC12A2 ASS1 GLYATL2 GMDS CYB5R2 FOXC1 MGAM2	1.04e-07	182	92	7	9b556e44ed6aaa50ec572224f5751fb02ce63438
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC12A2 AACS GLYATL2 GMDS FOXC1 MGAM2 CA6	1.16e-07	185	92	7	c4ca213a59ffab183a7719c2b4bc3f658a95002d
ToppCell	wk_08-11-Mesenchymal-Mesothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FLNC SFRP2 ASS1 KLK5 TMEM235 SLC51A TNNT1	1.65e-07	195	92	7	9016a44b521214546a55a822ebdef5b5312206d2
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC12A2 ACACA FARP1 AACS GMDS CPD DOP1B	1.96e-07	200	92	7	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC12A2 GLYATL2 GMDS CYB5R2 FOXC1 MGAM2	2.30e-06	184	92	6	00db9eaaffe9c598222e14b2f9638cbcce1602d7
ToppCell	(5)_Glands_duct\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	FARP1 GLYATL2 GMDS IRX1 MS4A7 FOXC1	2.44e-06	186	92	6	ad8d5010e5095508f4995e0c6c016a44e8ffb8dd
ToppCell	wk_08-11-Mesenchymal-Mesothelial-Early_mesothelial\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FLNC SFRP2 ASS1 KLK5 TMEM235 TNNT1	2.60e-06	188	92	6	6151051c027c7ff7d5d4bf5f1e11d7fe58eb22ed
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SFRP2 GLI3 LAMA4 FGF10 CPE VIT	2.60e-06	188	92	6	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SFRP2 GLI3 LAMA4 FGF10 CPE VIT	2.76e-06	190	92	6	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	droplet-Heart-HEART-1m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC CPD CPE RGS3 NR1D2 FOXC1	3.03e-06	193	92	6	d0a5f212f8e8a13dbbe3e41df92548ef82eef70b
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC12A2 FARP1 AACS GMDS CPD DOP1B	3.71e-06	200	92	6	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell	severe_COVID-19-CD8+_T_naive\|World / disease group, cell group and cell class (v2)	NELL2 CATSPERD ANKRD62 PLD6 CA6	1.65e-05	153	92	5	422483445af49c277fc8962d76a46ffafd872422
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SFRP2 IGF1R NIPAL2 CPE FOXC1	1.76e-05	155	92	5	8e239470799426ea474a36f57e1b7e0d9365ca5f
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX1 SFRP2 LAMA4 SLC45A2 VCL	2.05e-05	160	92	5	dd16ca90feb3ae88b6409d6c278b4765da565514
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TPP2 HAUS6 NELL2 TENM1 ANKRD62	2.11e-05	161	92	5	5fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCell	Ciliated_cells-A-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	WDR93 NELL2 CATSPERD MS4A7 FABP6	2.37e-05	165	92	5	0ebdbbdb151fb797335013d5838af1c7bbc45b06
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA1549L CPD CPE RGS3 FOXC1	2.59e-05	168	92	5	06dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell	facs-Heart-RA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA1549L CPD CPE RGS3 FOXC1	2.59e-05	168	92	5	1002f058a340763e3d8de0bd1f0547a903526ec6
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.4\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC12A2 ASS1 GLYATL2 SLC51A FOXC1	2.98e-05	173	92	5	176b956e71d98e8275d698b39437fc326e5fe449
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNC SFRP2 NRXN2 PLEKHA3 CPE	3.06e-05	174	92	5	4da79da7a09ee1e345102c5331675ebcdbe56171
ToppCell	Ciliated_cells-A-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	WDR93 RSPH10B2 CATSPERD MS4A7 FABP6	3.23e-05	176	92	5	1c364155f46b9a7c995bdc2cc2333c437cd90f5b
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ASS1 GLYATL2 SLC51A FOXC1 SPINK5	3.23e-05	176	92	5	8d9d0fb46c418b2067be58aec822e8c2b1561461
ToppCell	21-Trachea-Epithelial-Submucosal_gland\|Trachea / Age, Tissue, Lineage and Cell class	AACS GLYATL2 GMDS IRX1 FOXC1	3.41e-05	178	92	5	3e406e38eea0d38dc25edecf703c4c89ec6a28e0
ToppCell	3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC12A2 ASS1 GLYATL2 GMDS FOXC1	3.50e-05	179	92	5	ec331b1132f965581f851a3b29e62873c4140e6c
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IGFN1 SFRP2 LAMA4 FGF10 VIT	3.60e-05	180	92	5	c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IGFN1 SFRP2 LAMA4 FGF10 VIT	3.60e-05	180	92	5	32c6a3886428d82fb4355d987c6d2645f333447b
ToppCell	15-Airway-Epithelial-Submucosal_gland\|Airway / Age, Tissue, Lineage and Cell class	SLC12A2 AACS GLYATL2 IRX1 FOXC1	3.60e-05	180	92	5	283bb0d58811947bfda4e286b9ec87d869c8e29e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BMP7 PTPRD FARP1 GMDS CPE	3.69e-05	181	92	5	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell-SMG_mucous-SMG_mucous_L.0.6.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC12A2 GLYATL2 GMDS CPD CYB5R2	3.79e-05	182	92	5	6d7ba2e1f33aaa499a898ed9587197c0ee625e9a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BMP7 PTPRD FARP1 GMDS CPE	3.79e-05	182	92	5	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	facs-Spleen-nan-18m-Lymphocytic-Cd3e_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP7 SFRP2 IGF1R ASS1 PRKCA	3.79e-05	182	92	5	da3e9093cba791c7c282eb044656046252a32789
ToppCell	21-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high\|Trachea / Age, Tissue, Lineage and Cell class	SFRP2 NRXN2 LAMA4 CPE VIT	3.79e-05	182	92	5	354dcdb01360597f68c4fe157a682aee1c0b8bb1
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	SLC12A2 ASS1 PRKCA GMDS MGAM2	3.89e-05	183	92	5	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	droplet-Liver-Npc-21m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC SFRP2 NIPAL2 CPE IRX1	3.89e-05	183	92	5	99ab7a43527eb226027efbcd8c0b6a8e46fc3c93
ToppCell	droplet-Liver-Npc-21m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC SFRP2 NIPAL2 CPE IRX1	3.89e-05	183	92	5	28916f0597690ff534578be2cb715b485cb1de1a
ToppCell	facs-Heart-LA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NIPAL2 GMDS CPE RGS3 FOXC1	4.10e-05	185	92	5	1ecfca049c0c1110fd1b2256db7cb7abda6afb04
ToppCell	facs-Heart-LA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NIPAL2 GMDS CPE RGS3 FOXC1	4.10e-05	185	92	5	b6df1412b579d40ed5df806f9c54bd1fbb9a1e15
ToppCell	3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC12A2 GLYATL2 GMDS CPD CYB5R2	4.10e-05	185	92	5	d9039770226338fbc3fce92aa229fad96e16db8c
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	SFRP2 GLI3 LAMA4 CPE VIT	4.10e-05	185	92	5	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMP7 HAUS6 PTPRD LAMA4 GATA5	4.10e-05	185	92	5	9878392d79734ab5bb977d7f4f5e2e079b9a5353
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NELL2 ASS1 KLK5 TMEM235 TNNT1	4.10e-05	185	92	5	492529121cb9e88bd3c0db6b54af3cd2979572bc
ToppCell	3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell-SMG_mucous\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC12A2 GLYATL2 GMDS CPD CYB5R2	4.10e-05	185	92	5	b931ab35da10e6e3877071dce9b13fc0da63dc88
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGF1R NRXN2 CDK13 LAMA4 CYB5R2	4.21e-05	186	92	5	2cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCell	wk_15-18-Mesenchymal-Mesothelial-Early_mesothelial\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SFRP2 ASS1 KLK5 TMEM235 TNNT1	4.21e-05	186	92	5	ae4b6ecfc1850c0a01a11b9dd9718880f2a24fe0
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGF1R NRXN2 CDK13 LAMA4 CYB5R2	4.21e-05	186	92	5	90d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FARP1 GLI3 TENM1 SLC45A2 CPE	4.21e-05	186	92	5	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	SMG-Goblet\|World / shred by cell class for bronchial biopsy	SLC12A2 GLYATL2 GMDS CPD CPE	4.31e-05	187	92	5	5178118bdec91495253c88f58fd908cf831de7ef
ToppCell	Ciliated_cells-B-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	WDR93 NELL2 CATSPERD MS4A7 FABP6	4.31e-05	187	92	5	6fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCell	droplet-Lung-LUNG-1m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN2 CATSPERD LAMA4 CPE FOXC1	4.31e-05	187	92	5	9c9ae8725905ba0cfe407878006ed06c2480fb72
ToppCell	Ciliated_cells-B-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	WDR93 CATSPERD NME9 MS4A7 FABP6	4.31e-05	187	92	5	bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCell	droplet-Lung-LUNG-1m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN2 CATSPERD LAMA4 CPE FOXC1	4.31e-05	187	92	5	9e9460e57cdc9cd0a0de2866b140e06d0bc19a8f
ToppCell	droplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NRXN2 CATSPERD LAMA4 CPE FOXC1	4.42e-05	188	92	5	dc52dd2957be3f40001f0a56f3d9ac9d66ea466e
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	LAMA4 CPE RGS3 DISP1 FOXC1	4.42e-05	188	92	5	116ca07ee4413dcc0e9e5ac99bfee6ed7b7847c6
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FARP1 TENM1 SLC45A2 CPD VCL	4.42e-05	188	92	5	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NELL2 ASS1 KLK5 TMEM235 TNNT1	4.42e-05	188	92	5	9655a4c47b644a870017d349b99063e17dbae572
ToppCell	droplet-Lung-1m-Endothelial-lymphatic_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NRXN2 CATSPERD LAMA4 CPE FOXC1	4.42e-05	188	92	5	2ef08313087e91985bcffc46c3798470cdeec49c
ToppCell	droplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NRXN2 CATSPERD LAMA4 CPE FOXC1	4.42e-05	188	92	5	1f1604b6dc0a8ad0be3d9aac0bef448459c22465
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNC CPE GATA5 KLK5 TNNT1	4.42e-05	188	92	5	e82104f71bcdab7392fdb076dc3560255964fd9e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NELL2 IGF1R TENM1 PRKCA CA6	4.54e-05	189	92	5	e9df7ecd36bee1fedce23bb188c68a94fa60462c
ToppCell	18-Airway-Epithelial-Submucosal_gland\|Airway / Age, Tissue, Lineage and Cell class	SLC12A2 ASS1 GLYATL2 GMDS FOXC1	4.54e-05	189	92	5	c1ea2dc44cf5340378e56e0ffc2e6f64e6c95a58
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BMP7 GMDS CPE DISP1 FOXC1	4.65e-05	190	92	5	b855b8b7d3439023390ca44629c1a99f5d4c6801
ToppCell	cellseq2-Epithelial-Epithelial_Airway\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	WDR93 BMP7 CATSPERD RSPH10B FABP6	4.65e-05	190	92	5	17829f4de31b3d9e4d71ba4817d18842aa699773
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NIPAL2 GMDS CPE RGS3 FOXC1	4.65e-05	190	92	5	6f71a9f74af7cd9a674753cfc9833ebe5bba0fa2
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	TPP2 HAUS6 NELL2 TENM1 PRKCA	4.77e-05	191	92	5	9bb6a6b88f351217455765ba07a6acf11fda98f4
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ASS1 FGF10 KLK5 TMEM235 TNNT1	4.77e-05	191	92	5	4c4eb61e6179d2f8fc524d2f813db9cba84f67a2
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IGFN1 SFRP2 FGF10 CPE VIT	4.77e-05	191	92	5	2c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_tracheobronchial_serous_cell-SMG_serous_(bronchial)-SMG_serous_(bronchial)_L.0.6.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC12A2 GMDS CYB5R2 FOXC1 MGAM2	4.77e-05	191	92	5	13460059a0c1ed9f476cef28b8ad4c06349056c6
ToppCell	ASK440-Mesenchymal\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	SFRP2 PTPRD GLI3 TENM1 LAMA4	4.77e-05	191	92	5	f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCell	facs-Heart-RV-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NIPAL2 GMDS CPE RGS3 FOXC1	4.77e-05	191	92	5	f0c649bb32732c9dd38a0af8ce94d2a4d16de39a
ToppCell	ASK454-Mesenchymal\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	WDR93 BMP7 SFRP2 TENM1 LAMA4	4.77e-05	191	92	5	e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCell	10x5'v1-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FLNC SFRP2 GLI3 CPE ANKRD53	4.77e-05	191	92	5	44b1f62fdee03b157fe545f2ae6ff84f8929a8ac
ToppCell	ASK454-Mesenchymal-Fibroblast\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	WDR93 BMP7 SFRP2 TENM1 LAMA4	4.77e-05	191	92	5	1726add3f392a061536b7aff72ba84303f4a0b1f
ToppCell	ASK440-Mesenchymal-Fibroblast\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	SFRP2 PTPRD GLI3 TENM1 LAMA4	4.77e-05	191	92	5	387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCell	facs-Heart-RV-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NIPAL2 GMDS CPE RGS3 FOXC1	4.77e-05	191	92	5	e518c598719119e60c76016c586b1520c258bbcb
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC12A2 ASS1 GLYATL2 GMDS FOXC1	4.89e-05	192	92	5	c227ab1914191e839fc39c9adc2080026d4b04fc
ToppCell	droplet-Heart-nan-18m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NIPAL2 GMDS CPE RGS3 FOXC1	4.89e-05	192	92	5	0b9b2eaed45456d7d74ce78a64ef4a26ac2458fb
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC12A2 ASS1 GLYATL2 GMDS FOXC1	4.89e-05	192	92	5	bf187a57a559ab732bb815892af45ca922966ac6
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC12A2 ASS1 GLYATL2 GMDS FOXC1	4.89e-05	192	92	5	f573b2d205bd4d053a548af3fe3ff9de7be0cd2b
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	TPP2 HAUS6 NELL2 TENM1 PRKCA	4.89e-05	192	92	5	1c0ce299cee9ab5cdea256f3e8c1e5598577a8b6
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NELL2 IGF1R BACH2 PRKCA CA6	4.89e-05	192	92	5	ef8970e5389bd55c1624cd6dd01a7ca7abaa8950
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPE KLK5 TMEM235 TNNT1 DISP1	4.89e-05	192	92	5	2f539653a20006bef814e6b4acd1023d6fdad5c6
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Mesenchymal_3\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FLNC SFRP2 ASS1 CPE FOXC1	4.89e-05	192	92	5	d88753b200d9c8da6716222d697ddf0a1548d6c8
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NELL2 IGF1R BACH2 PRKCA CA6	5.01e-05	193	92	5	95f5611dd9583f339b7c9f52bb478af204fb89ad
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BMP7 FARP1 GMDS CPE FOXC1	5.01e-05	193	92	5	ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRD GLI3 LAMA4 FGF10 VIT	5.01e-05	193	92	5	9d0b966d13cbce97beb43de6dc77f006c363a181
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	USP34 FAM120A APOOL CPD GTF3C4	5.01e-05	193	92	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	GLI3 LAMA4 CPE RGS3 FOXC1	5.01e-05	193	92	5	5e46a9f65e85aca78f825fdef88a95b97eec8743
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BMP7 SFRP2 PTPRD LAMA4 CPE	5.01e-05	193	92	5	68089ba4123e2f9bea9aae0023a844b5a57bfc0e
ToppCell	COVID-19_Severe-CD8+_T_naive\|COVID-19_Severe / Disease condition and Cell class	NELL2 IGF1R BACH2 PRKCA CA6	5.01e-05	193	92	5	8ece109352d67b6a76bc87a2579e299c77c63137
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNC LAMA4 CPE GATA5 KLK5	5.14e-05	194	92	5	c578cf7c6b4d6f31f87dde8845de5b3891f16822
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibro-meso\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNC LAMA4 CPE GATA5 KLK5	5.14e-05	194	92	5	f4286ae7bb8350c42d50727ee8688b80129714f6
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SFRP2 PTPRD GLI3 LAMA4 FGF10	5.14e-05	194	92	5	8c37bedb23285735ff3828db3889897fada8c95d
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNC LAMA4 CPE GATA5 KLK5	5.14e-05	194	92	5	87461bd6d7f702c0a0f5e0c8ace3049125a51f9a
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	BMP7 ASS1 CPE VIT RGS3	5.14e-05	194	92	5	292ce9021678534c9eedb367b9772a9d976208a8
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BMP7 SFRP2 GMDS KLK5 FOXC1	5.14e-05	194	92	5	1374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SFRP2 PTPRD GLI3 LAMA4 FOXC1	5.14e-05	194	92	5	85e00861c5068a27d0cf0ae677f420c8245baa9a
ToppCell	10x5'v1-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	GLI3 LAMA4 CPE RGS3 FOXC1	5.26e-05	195	92	5	30ed961151b8b1f6ce37f06c9a061519f01c2864
ToppCell	Bronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SLC12A2 ASS1 GLYATL2 IRX1 FOXC1	5.26e-05	195	92	5	fc2a1d84b3d013e5cb9e7b9cdd740e4010897d20
ToppCell	(1)_T_cells-(1)_T_CD4_naive\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	NELL2 IGF1R BACH2 PRKCA CA6	5.26e-05	195	92	5	d3fa551bc6f5ee5890af1040415e61ecd5d46201
Drug	Nifuroxazide [965-52-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A	SEL1L USP34 MANBA NIPAL2 ZNF510 PRRC2B SPINK5	8.45e-06	188	88	7	4835_DN
Drug	Scopoletin [92-61-5]; Down 200; 20.8uM; MCF7; HT_HG-U133A	USP34 BMP7 MANBA NIPAL2 CPE KLK5 SPINK5	1.07e-05	195	88	7	6510_DN
Drug	Bacitracin [1405-87-4]; Down 200; 2.8uM; MCF7; HT_HG-U133A	SEL1L USP34 GLI3 NIPAL2 KLK5 VCPIP1 SPINK5	1.18e-05	198	88	7	6488_DN
Drug	Riboflavine [83-88-5]; Up 200; 10.6uM; PC3; HT_HG-U133A	BMP7 CELSR3 TENM1 NIPAL2 PRKCA SLC45A2 VAV1	1.22e-05	199	88	7	4485_UP
Disease	Primary familial dilated cardiomyopathy	LAMA4 SDHA VCL	9.49e-05	30	87	3	cv:C0340427
Disease	pappalysin-1 measurement	USP34 CHD7	1.28e-04	6	87	2	EFO_0802845
Disease	hypospadias (biomarker_via_orthology)	GLI3 FGF10	1.28e-04	6	87	2	DOID:10892 (biomarker_via_orthology)
Disease	Primary dilated cardiomyopathy	LAMA4 SDHA VCL	1.39e-04	34	87	3	cv:C0007193
Disease	Parkinson disease, disease progression measurement	PTPRD AACS NR1D2	2.10e-04	39	87	3	EFO_0008336, MONDO_0005180
Disease	dilated cardiomyopathy (is_implicated_in)	PRKCA GATA5 VCL	2.81e-04	43	87	3	DOID:12930 (is_implicated_in)
Disease	Familial dilated cardiomyopathy	LAMA4 SDHA VCL	3.00e-04	44	87	3	C0340427
Disease	Headache, glucose measurement	IGF1R MANBA	3.05e-04	9	87	2	EFO_0004468, HP_0002315
Disease	testosterone measurement	SOX1 HAUS6 SFRP2 MANBA PRKCA GMDS CHD7 IRX1 NME9 SLC51A NR1D2 FOXC1	3.57e-04	1275	87	12	EFO_0004908
Disease	Gastrointestinal Stromal Sarcoma	GLI3 DISP1 SDHA	3.65e-04	47	87	3	C3179349
Disease	Cardiomyopathy	LAMA4 SDHA VCL	3.65e-04	47	87	3	cv:C0878544
Disease	Gastrointestinal Stromal Tumors	GLI3 DISP1 SDHA	4.39e-04	50	87	3	C0238198
Disease	cardiac troponin T measurement	PTPRD GLI3 PRKCA SEL1L2 VCL	4.85e-04	219	87	5	EFO_0005043
Disease	essential hypertension, age at diagnosis	GMDS NME9 FOXC1	6.13e-04	56	87	3	EFO_0004918, MONDO_0001134
Disease	prostate carcinoma (is_implicated_in)	CDK13 PRKCA	6.56e-04	13	87	2	DOID:10286 (is_implicated_in)
Disease	pelvic organ prolapse	PTPRD SLC12A2 FARP1 CPE	7.15e-04	136	87	4	EFO_0004710
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	PHYH IGF1R ACACA	9.48e-04	65	87	3	DOID:0080208 (biomarker_via_orthology)
Disease	Tetralogy of Fallot	GATA5 FOXC1	1.00e-03	16	87	2	C0039685
Disease	Colorectal Carcinoma	FLNC SFRP2 PTPRD ACACA GLI3 TENM1 CPE GATA5	1.11e-03	702	87	8	C0009402
Disease	partial epilepsy	PTPRD ASS1	1.14e-03	17	87	2	EFO_0004263
Disease	exercise test	PTPRD PRKCA	1.58e-03	20	87	2	EFO_0004328
Disease	dilated cardiomyopathy	FLNC PRKCA	1.58e-03	20	87	2	EFO_0000407
Disease	cotinine measurement	SEL1L2 FABP6	2.09e-03	23	87	2	EFO_0007813
Disease	Prostatic Neoplasms	BMP7 SLC12A2 FGF10 CHD7 KLK5 FOXC1 SPINK5	2.31e-03	616	87	7	C0033578
Disease	Malignant neoplasm of prostate	BMP7 SLC12A2 FGF10 CHD7 KLK5 FOXC1 SPINK5	2.31e-03	616	87	7	C0376358
Disease	diabetes mellitus (implicated_via_orthology)	BMP7 IGF1R	2.67e-03	26	87	2	DOID:9351 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
HQEPGLMGDGMYNQV	BACH2	561	Q9BYV9
NQGKGMFKYSDHPLN	CATSPERD	216	Q86XM0
GMVSFHDNPEKYNNP	COPS3	356	Q9UNS2
MGHNFSLPVYKGEIQ	AACS	446	Q86V21
EHGANPNVRDMYGNT	ANKRD62	126	A6NC57
IMFQAYGDKQGPLHG	ACACA	1556	Q13085
GRHGPQNKQPFMVAF	BMP7	266	P18075
YETQAGEFPMVNNGH	CA6	71	P23280
YPGMQNERHGQSFVD	CHD7	126	Q9P2D1
NSQAKNLGMPVHAAY	DISP1	1221	Q96F81
KMHNYNYGGNLQENP	CDK13	1456	Q14004
GRNDLMEYAKQHGIP	ASS1	156	P00966
NVHPQYPEGGKMTQY	CYB5R2	91	Q6BCY4
VQTMKGHGNYQNCPV	RGS3	516	P49796
NVHAQDAMGYKPIDF	ANKRD53	236	Q8N9V6
RHGPGQMLFQNGDKY	MORN1	141	Q5T089
KYEGDFVKNVPMNHG	RSPH10B	131	P0C881
KYEGDFVKNVPMNHG	RSPH10B2	131	B2RC85
DKFNMNISGVFHPNG	DCAF1	1256	Q9Y4B6
GMQNQDPVGQGYLAH	GLI3	1311	P10071
LGQRNNAHGYFKGIM	NELL2	191	Q99435
NAHGYFKGIMQDVQL	NELL2	196	Q99435
NPQAHIEGNMKLHYG	GMDS	71	O60547
HDNGQKYLIIMNPGI	MGAM2	396	Q2M2H8
FGVNNAVYGIDAMNP	EIF3J	136	O75822
ENNPVRGPYGKMHIN	SPINK5	866	Q9NQ38
APGREQKYMLGTNHQ	DOP1B	211	Q9Y3R5
DERQPYAHMNGGRKN	IGF1R	1341	P08069
KPGHMYQNEDYLQNG	MS4A7	26	Q9GZW8
QEMGPHTVAVKYRGQ	FLNC	2281	Q14315
HLSGLVFNGQPYMDQ	NRXN2	881	Q9P2S2
QQMFQGVKSIPHPGY	KLK5	131	Q9Y337
PHKKSMLGNGNYDVN	JOSD1	71	Q15040
PVQGFDYAKQHLGQQ	KIAA1549L	1226	Q6ZVL6
MGVQGFQDYIEKHCP	FAM120A	1	Q9NZB2
NKTLHQGMPEVYNFD	PLBD1	526	Q6P4A8
HLGEQNMGAKFALFQ	SLC51A	246	Q86UW1
NACGLYHKMNGVNRP	GATA5	211	Q9BWX5
KFGAYMQVHIQNDGP	DTD1	126	Q8TEA8
SNQFKVHGQLPLYGM	FARP1	796	Q9Y4F1
GYPGQQQNFHSVREM	FOXC1	496	Q12948
YMEGNLGHPVFQTQF	UPB1	211	Q9UBR1
MEGGKLVVNFPNYHQ	FABP6	86	P51161
EFKYIGNMHGNEAVG	CPE	106	P16870
EFKYIGNMHGNEVVG	CPD	556	O75976
QHHEGGNKQMLYQAG	MANBA	586	O00462
NKMHALNGYLFGNFP	HEPHL1	266	Q6MZM0
MHAVNGYMYGNQPGL	HEPHL1	621	Q6MZM0
KQMFQLHIGNVYEAG	HAUS6	286	Q7Z4H7
SMNPANIYQFAVGGH	DCAF8L1	341	A6NGE4
HNGRQMYVALNGKGA	FGF10	171	O15520
GEMIPYGFNNQTKHC	IGFN1	251	Q86VF2
EGPNAHIMYQIVEGN	CELSR3	1096	Q9NYQ7
EGMKGLFQNPAVQFH	FLAD1	266	Q8NFF5
NGYVNPELAMQGAKN	SLC45A2	276	Q9UMX9
GYQVHYVRMENGEPK	PTPRD	746	P23468
VNGEYLNVHMKNGQV	LAMA4	1691	Q16363
SKYVEEQPGHLQMGF	APOOL	51	Q6UXV4
EGGVNKMFHGIQDYE	PHYH	226	O14832
QFKGRNIMHYPNGHA	NR1D2	321	Q14995
QMDPADYGKQHFNDV	GOLM2	421	Q6P4E1
KAGIQVRHDQDPGYM	PLD6	141	Q8N2A8
NDINAPYLVMGQKQG	SFRP2	251	Q96HF1
NMGAHFGGYLVKAEQ	TNNT1	156	P13805
HYFKKAADMGNPVGQ	SEL1L	436	Q9UBV2
VHYNMGGIPTNYKGQ	SDHA	406	P31040
NGGDLMYHIQQVGKF	PRKCA	421	P17252
PHYGEVNNDFVMLKG	RPL3L	321	Q92901
GKMYLEGNAAVPQNN	SEL1L2	341	Q5TEA6
QMGSQYELKDNPGVH	IRX1	91	P78414
QQSYIDFGNIPGKQM	NIPAL2	336	Q9H841
PKGHEIFNTYGQMAN	SETD6	276	Q8TBK2
IHKGNGENMFISQQP	TENM1	1151	Q9UKZ4
MQEAQLAYGQHPGAG	SOX1	206	O00570
AETVQQYGPQHMQGV	TMEM235	156	A6NFC5
QYGPQHMQGVRVSFG	TMEM235	161	A6NFC5
QSGAIMNKFYQPHEA	REV3L	141	O60673
IYPENATANGHDFQM	VAV1	506	P15498
PAFQMFAKGYGKNNE	SLC12A2	636	P55011
PGNQAAYEHFETMKN	VCL	686	P18206
DQNKRQMGSGDAYPH	TPP2	861	P29144
LMGVVQYGDNPATHF	VIT	331	Q6UXI7
VRKGASQFMGNVYHP	PRRC2B	261	Q5JSZ5
RAQYGTEMPFNAVHG	NME9	266	Q86XW9
GMINGLHPVNKNYQV	GTF3C4	496	Q9UKN8
AKGLPHMFQQGGVFY	VCPIP1	911	Q96JH7
PGEQHFYMKAVNAAE	PLEKHA3	66	Q9HB20
KMQQQGIPGGIFFHC	ZNF41	146	P51814
YFSVHKGQNMYPEGQ	WDR93	466	Q6P2C0
MGIKHYELNPSGNNF	ZNF510	331	Q9Y2H8
HFYMGTKGPENPQVE	USP34	2471	Q70CQ2
KPMAVAGANQYTFHL	RPE	81	Q96AT9
AYGPNGMNKMVINHL	CCT8	46	P50990
FYFQMHGEQNEVPGK	ZMAT1	86	Q5H9K5
GYTVPKYRHQGNMLQ	GLYATL2	226	Q8WU03