Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessglial cell proliferation

SOX11 CSF1R TREM2 MFN2

8.55e-0587554GO:0014009
GeneOntologyBiologicalProcessmacrophage colony-stimulating factor signaling pathway

CSF1R TREM2

1.45e-047552GO:0038145
GeneOntologyBiologicalProcesscellular component maintenance

SHANK1 CSF1R TREM2 TANC1

1.52e-04101554GO:0043954
GeneOntologyBiologicalProcessestablishment of skin barrier

HRNR TMPRSS11F FLG2

1.78e-0441553GO:0061436
GeneOntologyBiologicalProcesspostsynapse organization

SHANK1 LRFN1 TREM2 LRP4 MFN2 TANC1

1.81e-04313556GO:0099173
GeneOntologyBiologicalProcessamyloid-beta clearance by cellular catabolic process

TREM2 LRP4

1.93e-048552GO:0150094
GeneOntologyBiologicalProcesspositive regulation of osteoclast differentiation

CSF1R TREM2 TNFRSF11A

2.20e-0444553GO:0045672
GeneOntologyBiologicalProcesscell junction organization

SHANK1 LRFN1 CSF1R TREM2 LAMA3 LRP4 MFN2 LAMB2 TANC1 PCDH17

2.22e-049745510GO:0034330
GeneOntologyBiologicalProcessregulation of astrocyte activation

CSF1R TREM2

2.48e-049552GO:0061888
GeneOntologyBiologicalProcessmicroglial cell proliferation

CSF1R TREM2

2.48e-049552GO:0061518
GeneOntologyBiologicalProcessdendritic spine organization

SHANK1 TREM2 MFN2 TANC1

2.51e-04115554GO:0097061
GeneOntologyBiologicalProcessastrocyte development

CSF1R TREM2 LAMB2

2.68e-0447553GO:0014002
GeneOntologyBiologicalProcessglomerular epithelial cell development

JAG1 LAMB2

3.10e-0410552GO:0072310
GeneOntologyBiologicalProcesspodocyte development

JAG1 LAMB2

3.10e-0410552GO:0072015
GeneOntologyCellularComponentlaminin-3 complex

LAMA3 LAMB2

2.04e-053552GO:0005608
GeneOntologyCellularComponentcell surface

CD1D LRFN1 STAB2 CSF1R ADGRG2 KCNJ3 CD34 TREM2 LRP4 TNFRSF11A CTNND1 TMPRSS11F

2.51e-0511115512GO:0009986
GeneOntologyCellularComponentkeratohyalin granule

HRNR FLG2

6.76e-055552GO:0036457
GeneOntologyCellularComponentlaminin complex

LAMA3 LAMB2

3.02e-0410552GO:0043256
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

LAMA2 LAMB2

9.01e-0417552GO:0098637
HumanPhenoTriceps weakness

JAG1 LRP4 MFN2 ADSS1

1.32e-0618254HP:0031108
HumanPhenoProximal muscle weakness in upper limbs

JAG1 LAMA2 LRP4 MFN2 ADSS1

1.58e-0568255HP:0008997
DomainEGF_Lam

STAB2 MEGF6 LAMA2 LAMA3 LAMB2 PEAR1

7.48e-1035556SM00180
DomainLaminin_EGF

STAB2 MEGF6 LAMA2 LAMA3 LAMB2 PEAR1

1.26e-0938556IPR002049
DomainEGF

SNED1 STAB2 MEGF6 JAG1 LAMA2 LAMA3 LRP4 LAMB2 PEAR1

2.61e-08235559SM00181
DomainEGF-like_dom

SNED1 STAB2 MEGF6 JAG1 LAMA2 LAMA3 LRP4 LAMB2 PEAR1

4.29e-08249559IPR000742
DomainEGF_1

SNED1 STAB2 MEGF6 JAG1 LAMA2 LAMA3 LRP4 LAMB2 PEAR1

5.26e-08255559PS00022
DomainLaminin_EGF

MEGF6 LAMA2 LAMA3 LAMB2 PEAR1

5.58e-0835555PF00053
DomainEGF-like_CS

SNED1 STAB2 MEGF6 JAG1 LAMA2 LAMA3 LRP4 LAMB2 PEAR1

6.42e-08261559IPR013032
DomainEGF_2

SNED1 STAB2 MEGF6 JAG1 LAMA2 LAMA3 LRP4 LAMB2 PEAR1

7.32e-08265559PS01186
DomainEGF_LAM_2

STAB2 LAMA2 LAMA3 LAMB2

1.74e-0630554PS50027
DomainEGF_LAM_1

STAB2 LAMA2 LAMA3 LAMB2

1.74e-0630554PS01248
DomainGrowth_fac_rcpt_

STAB2 MEGF6 JAG1 LAMA3 LRP4 LAMB2

6.38e-06156556IPR009030
DomainLaminin_N

LAMA2 LAMA3 LAMB2

1.32e-0516553IPR008211
DomainLAMININ_NTER

LAMA2 LAMA3 LAMB2

1.32e-0516553PS51117
DomainLaminin_N

LAMA2 LAMA3 LAMB2

1.32e-0516553PF00055
DomainLamNT

LAMA2 LAMA3 LAMB2

1.32e-0516553SM00136
DomainEGF_CA

SNED1 STAB2 MEGF6 JAG1 LRP4

2.93e-05122555SM00179
DomainEGF-like_Ca-bd_dom

SNED1 STAB2 MEGF6 JAG1 LRP4

3.17e-05124555IPR001881
DomainEGF

SNED1 STAB2 MEGF6 JAG1 LRP4

3.43e-05126555PF00008
DomainEGF_3

SNED1 STAB2 MEGF6 JAG1 LRP4 PEAR1

6.45e-05235556PS50026
DomainhEGF

SNED1 MEGF6 JAG1

7.51e-0528553PF12661
DomainLaminin_aI

LAMA2 LAMA3

8.47e-055552IPR009254
DomainLaminin_I

LAMA2 LAMA3

8.47e-055552PF06008
DomainLaminin_II

LAMA2 LAMA3

8.47e-055552PF06009
DomainLaminin_domII

LAMA2 LAMA3

8.47e-055552IPR010307
DomainEGF_Ca-bd_CS

SNED1 MEGF6 JAG1 LRP4

1.90e-0497554IPR018097
DomainEGF_CA

SNED1 MEGF6 JAG1 LRP4

2.06e-0499554PS01187
DomainASX_HYDROXYL

SNED1 MEGF6 JAG1 LRP4

2.14e-04100554PS00010
DomainLAMININ_IVA

LAMA2 LAMA3

2.36e-048552PS51115
DomainLaminin_B

LAMA2 LAMA3

2.36e-048552PF00052
DomainLamB

LAMA2 LAMA3

2.36e-048552SM00281
DomainLaminin_IV

LAMA2 LAMA3

2.36e-048552IPR000034
DomainEGF-type_Asp/Asn_hydroxyl_site

SNED1 MEGF6 JAG1 LRP4

2.68e-04106554IPR000152
DomainEGF_extracell

STAB2 MEGF6 JAG1

7.34e-0460553IPR013111
DomainEGF_2

STAB2 MEGF6 JAG1

7.34e-0460553PF07974
DomainEMI_domain

MEGF6 PEAR1

9.95e-0416552IPR011489
DomainEMI

MEGF6 PEAR1

1.13e-0317552PS51041
DomainEGF_CA

MEGF6 JAG1 LRP4

2.08e-0386553PF07645
DomainS100_CABP

HRNR FLG2

2.85e-0327552PS00303
DomainS_100

HRNR FLG2

2.85e-0327552PF01023
DomainS100_Ca-bd_sub

HRNR FLG2

3.06e-0328552IPR013787
DomainS100/CaBP-9k_CS

HRNR FLG2

3.06e-0328552IPR001751
DomainS_100

HRNR FLG2

3.06e-0328552SM01394
Domain-

SNED1 CD1D LRFN1 CSF1R NXPE4 TREM2 CAMTA1

3.18e-036635572.60.40.10
DomainIg_E-set

NXPE4 KCNJ3 CAMTA1

3.57e-03104553IPR014756
DomainIg-like_fold

SNED1 CD1D LRFN1 CSF1R NXPE4 TREM2 CAMTA1

4.49e-03706557IPR013783
DomainLAM_G_DOMAIN

LAMA2 LAMA3

5.59e-0338552PS50025
PathwayPID_INTEGRIN4_PATHWAY

LAMA2 LAMA3 LAMB2

4.60e-0611443M158
PathwayREACTOME_ECM_PROTEOGLYCANS

LAMA2 LAMA3 LRP4 LAMB2

8.99e-0576444M27219
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

LAMA2 LAMA3 LAMB2

1.09e-0430443M27772
PathwayREACTOME_LAMININ_INTERACTIONS

LAMA2 LAMA3 LAMB2

1.09e-0430443M27216
PathwayWP_ALPHA_6_BETA_4_SIGNALING

LAMA2 LAMA3 LAMB2

1.45e-0433443M39503
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

LAMA2 LAMA3 LAMB2

2.78e-0441443M27778
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

LAMA2 LAMA3 LAMB2

3.92e-0446443M239
Pubmed

Laminins promote the locomotion of skeletal myoblasts via the alpha 7 integrin receptor.

LAMA2 LAMA3 LAMB2

1.38e-0775639004048
Pubmed

Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.

LAMA2 LAMA3 LAMB2

4.71e-07105639034910
Pubmed

Regional differences in the expression of laminin isoforms during mouse neural tube development.

LAMA2 LAMA3 LAMB2

6.46e-071156321524702
Pubmed

Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.

LAMA2 LAMA3 LAMB2

8.61e-07125639396756
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PCNX2 SPHK2 LRFN1 MEGF6 CTC1 LRP4 MFN2 LAMB2 TANC1 MED13L PRAG1

1.27e-061105561135748872
Pubmed

Basement membrane composition in the early mouse embryo day 7.

LAMA2 LAMA3 LAMB2

1.77e-061556315895400
Pubmed

Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.

LAMA2 LAMA3 LAMB2

2.18e-061656317601529
Pubmed

Macromolecular organization of basement membranes.

LAMA2 LAMA3

2.55e-0625628939648
Pubmed

Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Interacts With Colony-Stimulating Factor 1 Receptor (CSF1R) but Is Not Necessary for CSF1/CSF1R-Mediated Microglial Survival.

CSF1R TREM2

2.55e-06256233841415
Pubmed

1,25-Dihydroxyvitamin D3 inhibits directly human osteoclastogenesis by down-regulation of the c-Fms and RANK expression.

CSF1R TNFRSF11A

2.55e-06256223116709
Pubmed

Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.

LAMA2 LAMA3 LAMB2

3.17e-061856311311202
Pubmed

Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.

LAMA2 LAMA3 LAMB2

4.42e-062056322911573
Pubmed

Gab2 promotes colony-stimulating factor 1-regulated macrophage expansion via alternate effectors at different stages of development.

CSF1R GAB2

7.63e-06356221930791
Pubmed

Defects of filaggrin-like proteins in both lesional and nonlesional atopic skin.

HRNR FLG2

7.63e-06356223403047
Pubmed

Laminin isoforms in development and disease.

LAMA2 LAMB2

7.63e-06356217426950
Pubmed

Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.

LAMA2 LAMA3 LAMB2

1.00e-052656324742657
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

LAMA2 LAMA3 LAMB2

1.40e-052956322613833
Pubmed

Increasing diagnostic accuracy to grade dysplasia in Barrett's esophagus using an immunohistochemical panel for CDX2, p120ctn, c-Myc and Jagged1.

JAG1 CTNND1

1.52e-05456226926447
Pubmed

Developmental expression of nicein adhesion protein (laminin-5) subunits suggests multiple morphogenic roles.

LAMA3 LAMB2

1.52e-0545628081888
Pubmed

Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits.

LAMA2 LAMB2

1.52e-0545622099832
Pubmed

The molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesis.

TNFRSF11A GAB2

1.52e-05456215750601
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PCNX2 PDE3B SGSM1 MEGF6 KCNJ3 LAMA3 TANC1 CTNND1 CAMTA1 ZNF107 ADSS1

2.15e-051489561128611215
Pubmed

Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach.

LAMA2 LAMA3

2.54e-05556211969289
Pubmed

Developmental origin, functional maintenance and genetic rescue of osteoclasts.

CSF1R TNFRSF11A

2.54e-05556230971820
Pubmed

Differential expression of five laminin alpha (1-5) chains in developing and adult mouse kidney.

LAMA2 LAMA3

2.54e-0555629415429
Pubmed

Properly formed but improperly localized synaptic specializations in the absence of laminin alpha4.

LAMA2 LAMB2

2.54e-05556211369940
Pubmed

Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha3B and alpha5 chains.

LAMA2 LAMA3

2.54e-05556211829758
Pubmed

Differential expression of laminin alpha chains during murine tooth development.

LAMA2 LAMA3

2.54e-0555629389447
Pubmed

Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.

LAMA2 LAMA3 LAMB2

3.74e-054056327068110
Pubmed

Cross-linking of laminin-nidogen complexes by tissue transglutaminase. A novel mechanism for basement membrane stabilization.

LAMA2 LAMB2

3.80e-0565621678389
Pubmed

Structural elucidation of full-length nidogen and the laminin-nidogen complex in solution.

LAMA2 LAMB2

3.80e-05656223948589
Pubmed

A synaptic nidogen: developmental regulation and role of nidogen-2 at the neuromuscular junction.

LAMA2 LAMB2

3.80e-05656218817539
Pubmed

Entactin: structure and function.

LAMA2 LAMB2

3.80e-0565622119632
Pubmed

HIV-protein-mediated alterations in T cell interactions with the extracellular matrix proteins and endothelium.

LAMA2 LAMA3

3.80e-0565629597096
Pubmed

Impaired primary mouse myotube formation on crosslinked type I collagen films is enhanced by laminin and entactin.

LAMA2 LAMB2

3.80e-05656226555376
Pubmed

Developmental Apoptosis Promotes a Disease-Related Gene Signature and Independence from CSF1R Signaling in Retinal Microglia.

CSF1R TREM2

3.80e-05656231091440
Pubmed

Effect of basement membrane entactin on epidermal cell attachment and growth.

LAMA2 LAMB2

3.80e-0565623794389
Pubmed

Laminin-nidogen complex. Extraction with chelating agents and structural characterization.

LAMA2 LAMB2

3.80e-0565623109910
Pubmed

A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.

SNED1 CTNND1 HRNR LUZP1

4.04e-0511856430979931
Pubmed

Proteome-wide analysis of phospho-regulated PDZ domain interactions.

SHANK1 CD1D TANC1

4.34e-054256330126976
Pubmed

A new nomenclature for the laminins.

LAMA3 LAMB2

5.32e-0575627921537
Pubmed

CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages.

CSF1R TNFRSF11A

5.32e-05756230538245
Pubmed

Laminin isoforms in fetal and adult human adrenal cortex.

LAMA2 LAMB2

5.32e-05756214557481
Pubmed

Early estrogen-induced gene 1, a novel RANK signaling component, is essential for osteoclastogenesis.

TNFRSF11A GAB2

7.09e-05856223478294
Pubmed

Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain.

LAMA2 LAMA3

7.09e-0585629852162
Pubmed

Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.

LAMA2 LAMA3

7.09e-0585628872465
Pubmed

Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.

MEGF6 LRP4

9.10e-0595629693030
Pubmed

The extracellular-matrix protein matrilin 2 participates in peripheral nerve regeneration.

LAMA2 LAMB2

9.10e-05956219295126
Pubmed

Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.

MEGF6 JAG1

9.10e-05956212122015
Pubmed

Analysis of recently identified osteoporosis susceptibility genes in Han Chinese women.

LRP4 TNFRSF11A

1.14e-041056220554715
Pubmed

A human MAP kinase interactome.

SHANK1 CLIP2 LAMA3 LAMB2 TXLNG GAB2

1.30e-0448656620936779
Pubmed

Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity.

CD34 JAG1

1.39e-041156215875024
Pubmed

Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin.

CD34 LAMB2

1.39e-041156211435469
Pubmed

Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung.

LAMA2 LAMA3

1.39e-041156212051813
Pubmed

Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.

LAMA2 LAMB2

1.39e-041156223472759
Pubmed

Hypermethylation of UCHL1 Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing Degradation of Cortactin (CTTN).

LAMA3 HRNR FLG2

1.61e-046556332120844
Pubmed

Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning.

LAMA2 LAMB2

1.66e-041256226794322
Pubmed

Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.

LAMA2 LAMA3

1.66e-041256216750824
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

MEGF6 LAMA2 LAMA3 LAMB2

1.85e-0417556428071719
Pubmed

A novel scaffold protein, TANC, possibly a rat homolog of Drosophila rolling pebbles (rols), forms a multiprotein complex with various postsynaptic density proteins.

SHANK1 TANC1

1.96e-041356215673434
Pubmed

The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.

LAMA2 LAMB2

1.96e-041356236350252
Pubmed

Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development.

CSF1R TNFRSF11A

1.96e-041356237704707
Pubmed

Phosphoproteome analysis of HeLa cells using stable isotope labeling with amino acids in cell culture (SILAC).

LAMA2 CTNND1

1.96e-041356216212419
Pubmed

Fukutin-related protein alters the deposition of laminin in the eye and brain.

LAMA2 LAMA3

1.96e-041356221900571
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

CNOT6 TANC1 CTNND1 MED13L CAMTA1 SLC25A28

2.20e-0453656615840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

CNOT6 TANC1 CTNND1 MED13L CAMTA1 SLC25A28

2.25e-0453856610512203
Pubmed

New sequence variants associated with bone mineral density.

LRP4 TNFRSF11A

2.29e-041456219079262
Pubmed

The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform.

LAMA2 LAMA3

2.29e-04145629151674
Pubmed

Laminin alpha5 chain is required for intestinal smooth muscle development.

LAMA2 LAMB2

2.64e-041556212921739
Pubmed

Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.

LAMA2 LAMA3

2.64e-04155629264260
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

LAMA2 LAMA3 LAMB2

2.87e-047956318757743
Pubmed

TRIM30 modulates Interleukin-22-regulated papillary thyroid Cancer cell migration and invasion by targeting Sox17 for K48-linked Polyubiquitination.

HRNR FLG2

3.01e-041656231823782
Pubmed

Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.

LAMA2 LAMB2

3.01e-041656217948866
Pubmed

Local network topology in human protein interaction data predicts functional association.

TNFRSF11A GAB2

3.01e-041656219641626
Pubmed

Beta1-integrins are critical for cerebellar granule cell precursor proliferation.

LAMA2 LAMB2

3.41e-041756215056720
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

CLIP2 CTNND1 PRAG1 LUZP1

4.27e-0421856433378226
Pubmed

Barx2 and Fgf10 regulate ocular glands branching morphogenesis by controlling extracellular matrix remodeling.

LAMA2 LAMB2

4.75e-042056221750040
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

MEGF6 CLIP2 MED13L CAMTA1

4.81e-0422556412168954
Pubmed

Variation in genes of the epidermal differentiation complex in German atopic dermatitis patients.

HRNR FLG2

5.24e-042156219601998
Pubmed

Hematopoietic growth factor receptor genes as markers of lineage commitment during in vitro development of hematopoietic cells.

CSF1R CD34

5.24e-04215628499630
Pubmed

Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.

JAG1 MED13L

5.24e-042156225249183
Pubmed

Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac.

CSF1R CD34

5.76e-04225629324354
Pubmed

Sox4 links tumor suppression to accelerated aging in mice by modulating stem cell activation.

SOX11 CHEK2

6.87e-042456225043184
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

ACLY TANC1 CTNND1 LUZP1

7.80e-0425656433397691
Pubmed

Congenital Myasthenic Syndromes Overview

LRP4 LAMB2

8.07e-042656220301347
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

JAG1 LAMA3

8.07e-042656234189436
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SHANK1 LRFN1 CLIP2 MFN2 ZNFX1 CTNND1 LUZP1

8.69e-0496356728671696
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

SHANK1 CRNKL1 CLIP2 LRP4 ZNFX1 MED13L ST18 TXLNG

9.98e-04128556835914814
Pubmed

Dynamic MAPK/ERK Activity Sustains Nephron Progenitors through Niche Regulation and Primes Precursors for Differentiation.

JAG1 CTNND1

1.01e-032956230220628
Pubmed

The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity.

SHANK1 CTNND1

1.01e-032956219208628
Pubmed

Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT).

SOX11 JAG1

1.15e-033156229459093
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

PDE3B SGSM1 MEGF6 ACLY HRNR PCDH17

1.16e-0373656629676528
Pubmed

Identification of 14-3-3epsilon substrates from embryonic murine brain.

ACLY CTNND1 GAB2

1.28e-0313256316944949
Pubmed

The DNA sequence and biological annotation of human chromosome 1.

CD1D MEGF6 CD34 MFN2 HRNR CAMTA1 LUZP1

1.29e-03103156716710414
Pubmed

Postmitotic Hoxa5 Expression Specifies Pontine Neuron Positional Identity and Input Connectivity of Cortical Afferent Subsets.

SOX11 ST18

1.38e-033456232553152
GeneFamilyLaminin subunits

LAMA2 LAMA3 LAMB2

1.44e-0612353626
GeneFamilyEF-hand domain containing|S100 fused type protein family

HRNR FLG2

7.60e-0573521350
GeneFamilyADAM metallopeptidase domain containing|CD molecules

CD1D CSF1R CD34 JAG1 TNFRSF11A

9.08e-04394355471
ToppCellControl_saline|World / Treatment groups by lineage, cell group, cell type

PDE3B CD34 JAG1 LAMB2 TANC1 CTNND1 PCDH17

5.75e-0919956711c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SNED1 SOX11 MEGF6 JAG1 TANC1 PRAG1

1.52e-07192566c4efc170852abbcf0c53c2b0f8a0cc9fe7f116c8
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B CD34 TANC1 CTNND1 PCDH17 LUZP1

1.57e-07193566a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SNED1 SOX11 JAG1 LAMA2 TANC1 PRAG1

1.61e-07194566fb80a0271ccb1cb3f954ebcf2c5945cb6adb6b8c
ToppCellControl_saline-Endothelial-Endothelial|Control_saline / Treatment groups by lineage, cell group, cell type

PDE3B CD34 TANC1 CTNND1 PCDH17 LUZP1

1.93e-07200566e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PDE3B CD34 TANC1 CTNND1 PCDH17 LUZP1

1.93e-0720056679e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PDE3B CD34 TANC1 CTNND1 PCDH17 LUZP1

1.93e-07200566b7533c571eeea0cb3678e1a57d3dc036fa8d0f49
ToppCellControl_saline-Endothelial|Control_saline / Treatment groups by lineage, cell group, cell type

PDE3B CD34 TANC1 CTNND1 PCDH17 LUZP1

1.93e-072005663372c488a39fe812fa94e4f0564594186fea3db5
ToppCelldroplet-Lung-3m-Hematologic-myeloid-intermediate_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF1R NXPE4 TREM2 UNC93B1 ADSS1

1.28e-06150565b37f538ca5f976b509efe35dc81115b72b227084
ToppCelldroplet-Lung-3m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF1R NXPE4 TREM2 UNC93B1 ADSS1

1.28e-061505652c7518918c40e1bf679a2d4e83b472ee6f2f9df8
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CD1D CSF1R TNFRSF11A CTNND1 ST18

1.61e-06157565e9d0300361b06aec3c216f8af15f09e14b12a4da
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SNED1 SOX11 LRP4 TANC1 PRAG1

1.61e-06157565b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CD1D CSF1R TNFRSF11A CTNND1 ST18

1.66e-06158565e9657d8960d499832f9f9b45b5a6f4388551b7e1
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 CSF1R ADGRG2 TREM2 TNFRSF11A

1.87e-061625652787be283b7a705647058aeb9bc54006ce5ffe95
ToppCelldroplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF1R NXPE4 TREM2 UNC93B1 ADSS1

2.24e-061685653d8c431a3c8899383212fe6a7627889c40c5f3ef
ToppCelldroplet-Spleen-nan-21m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R MEGF6 NXPE4 TREM2 ADSS1

2.37e-0617056503cb4e508356f85372a588c8d1c6babf2a012683
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 CSF1R ADGRG2 TREM2 TNFRSF11A

2.37e-061705658d3c51364a332020810836e2055c60893c10d7f3
ToppCelldroplet-Spleen-nan-21m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 CSF1R MEGF6 NXPE4 TREM2

2.44e-061715659498c35b2a2c3a339dc8c5d49c8ec20d8ad52753
ToppCelldroplet-Spleen-nan-21m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 CSF1R MEGF6 NXPE4 TREM2

2.44e-06171565db544252f98e073e5bb4bec4a110cd58e6434435
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CSF1R TREM2 UNC93B1 TNFRSF11A ST18

2.51e-06172565f0e767a20d93e546ce278db67dbd779cc68af533
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CSF1R TREM2 UNC93B1 TNFRSF11A ST18

2.66e-06174565f520b79d277e286c9bb5d091e6c94e7ec7e46699
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3B CSF1R CTC1 TREM2 UNC93B1

2.81e-06176565d687e6c3f9043f2574d072f815b8c2258f9dc7b5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3B CSF1R CTC1 TREM2 UNC93B1

2.81e-061765654f37854124d77ee64dcb40fd491eaed2ba389891
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Myeloid-microglial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3B CSF1R CTC1 TREM2 UNC93B1

2.81e-061765650afba8707b847e5bdf6f38fe4379967631fe2240
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic-MPP_Fraction_B|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX11 CSF1R TREM2 TNFRSF11A ST18

2.89e-061775654a697866ed542d3201714234cee03451adf1dcc9
ToppCelldroplet-Spleen-nan-24m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R NXPE4 CD34 TREM2 ADSS1

2.89e-061775655f20a1a875d6f85ec07b097e6afdb07c2f8f88ff
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SNED1 SGSM1 STAB2 TNFRSF11A PEAR1

3.31e-061825652cc434e46985c66fc36de05344a67aa96d90abc9
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SNED1 SGSM1 STAB2 TNFRSF11A PEAR1

3.31e-061825650cde2775bdaaa2172499925bd59b0ac2d545eb27
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SNED1 SGSM1 STAB2 TNFRSF11A PEAR1

3.31e-061825653e7457b2a70b45735fb75d6617b7f34cef28758e
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_3|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SNED1 SOX11 LRP4 TANC1 PRAG1

3.40e-06183565f4ea7113ce9099222743d9ff02388d3d8a9e987b
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

PCNX2 PDE3B CD34 LAMA2 GAB2

3.78e-061875654ea486991f66c29728d127171a07b81404ec0b78
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

CD1D MEGF6 LAMA2 PRAG1 PEAR1

3.88e-06188565c90669b51e1902fe7726555290c91c92a911df83
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B CD34 TANC1 CTNND1 PCDH17

4.09e-06190565474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCell10x5'v1-week_12-13-Myeloid_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CSF1R TREM2 MYEOV TNFRSF11A TUBA8

4.19e-06191565be2fe2583bdcee0b35c43a347da9c4adb93e30e0
ToppCell10x5'v1-week_12-13-Myeloid_macrophage-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CSF1R TREM2 MYEOV TNFRSF11A TUBA8

4.19e-061915654cebaf31d4f09f4ab273a819ad5cbff7d9a9b341
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SNED1 SOX11 JAG1 TANC1 PRAG1

4.30e-061925654c9d748f209cc1e13d28c8c7f5180ab8522e0fbf
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SNED1 SOX11 LRP4 TANC1 PRAG1

4.41e-061935652f203f6f0c2135acb046c9351a633c3b5b254a46
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B CD34 TANC1 CTNND1 PCDH17

4.52e-0619456543f92b0533e26633dc94cce554045d641ef8fd76
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B CD34 TANC1 CTNND1 PCDH17

4.52e-061945651d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B CD34 TANC1 CTNND1 PCDH17

4.52e-0619456558f069efdefa0366033764446b9d6ffd4a17807e
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B CD34 TANC1 CTNND1 PCDH17

4.52e-06194565bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

PCNX2 SNED1 PDE3B LAMA2 GAB2

4.64e-06195565a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellASK454-Endothelial|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

CD34 LAMB2 PCDH17 LUZP1 PEAR1

4.75e-0619656514dd6956ef420b660be0baf52a66960e57d75d16
ToppCell(4)_Endothelial_cells-(41)_EC-arteriolar|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

SOX11 NXPE4 CD34 LRP4 PCDH17

4.87e-06197565482e3f8926880afed88ed37553ed2b5ed58b8c99
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PDE3B CSF1R TREM2 ZNFX1 LUZP1

5.12e-06199565b0a906586e58009f5ed9272fc29ba28e49c85ee6
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PDE3B CD34 CTNND1 PCDH17 LUZP1

5.25e-0620056572ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CD34 TANC1 CTNND1 PCDH17 LUZP1

5.25e-06200565bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PDE3B CD34 CTNND1 PCDH17 LUZP1

5.25e-062005655c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellControl_saline-Endothelial-Endothelial-Alv_Gen_Intermediate|Control_saline / Treatment groups by lineage, cell group, cell type

PDE3B CD34 CTNND1 PCDH17 LUZP1

5.25e-06200565041a34080120c9f613373c20dcc366292f558040
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PDE3B CD34 CTNND1 PCDH17 LUZP1

5.25e-06200565a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCellLPS_anti-TNF-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PDE3B CD34 CTNND1 PCDH17 LUZP1

5.25e-062005651d105eeda5a2c51f9a4654ffc79b7e2348ad593b
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PDE3B CD34 CTNND1 PCDH17 LUZP1

5.25e-0620056558a7ece7dfdf6c46f2a50cbcb580574dec14c748
ToppCellLPS_IL1RA_TNF-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PDE3B CD34 CTNND1 PCDH17 LUZP1

5.25e-06200565d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCellLPS_anti-TNF-Endothelial-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PDE3B CD34 CTNND1 PCDH17 LUZP1

5.25e-0620056560d2cbf41f37f1b11eddb4c9d9246c9c1fc5a5af
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

CD34 TANC1 CTNND1 PCDH17 LUZP1

5.25e-06200565432384faeade8e609154fab3d96c955a8ec868dd
ToppCellEndothelial-G|World / shred on cell class and cell subclass (v4)

SNED1 STAB2 TNFRSF11A PEAR1

1.81e-051245644b72809463f2986b7d1b7ab9de633ac4d7854a92
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LAMA3 TUBA8 PCDH17 ADSS1

2.91e-051405642c44e8cc5190226049be7ebc465d685393e701c4
ToppCelldroplet-Lung-nan-3m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R NXPE4 UNC93B1 ADSS1

3.16e-051435644d11d53330a9197275a8851e1bbf55a113715a09
ToppCelldroplet-Lung-nan-3m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R NXPE4 UNC93B1 ADSS1

3.16e-051435648b9f4d87d5faac7752c83e1992491fc5550600f8
ToppCellfacs-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF1R NXPE4 TNFRSF11A ADSS1

3.43e-0514656426493014daa432db721613ef480d133f3da9eb58
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CSF1R TREM2 UNC93B1 TNFRSF11A

4.22e-0515456479ebda35dd1719e157738d7c13e5b8ccc3991f03
ToppCellPND07-28-samps-Myeloid-Granulocyte-neutrophil__Lgals3-negative|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CSF1R NXPE4 UNC93B1 ADSS1

4.44e-05156564166f7b1220eaf8e1149dde260dd85a094855c54f
ToppCellPND07-28-samps-Myeloid-Granulocyte|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CSF1R NXPE4 UNC93B1 ADSS1

4.44e-051565645e1c5a7c9293b886920739cf766521df7f69726c
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHANK1 NXPE4 ST18 GAB2

4.55e-05157564ec433d2fe827abdb647be4176c231b7052482b6f
ToppCellfacs-Marrow-B-cells-24m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R TREM2 TNFRSF11A FLG2

4.55e-051575640966e347f8d32b13f8a3b3afba3f64637c69cdf9
ToppCellfacs-Marrow-B-cells-24m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R TREM2 TNFRSF11A FLG2

4.55e-051575646ebfedd91d62c6d4aa8f046657a899a279f82ba2
ToppCellfacs-Lung-3m-Hematologic-myeloid-intermediate_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF1R NXPE4 TREM2 ADSS1

4.66e-05158564b35bab2b93d0af821bfae18a358eb7dddaf3860f
ToppCellfacs-Lung-3m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF1R NXPE4 TREM2 ADSS1

4.66e-051585647bd4a64a610eb1cbcd3d07ea5258a55107cf6c00
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDE3B CSF1R TREM2 TNFRSF11A

4.78e-05159564c0e55f25271f788c08fa4b95186501fc27b2ec39
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 CD34 LAMA2 PCDH17

5.02e-051615641b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCelldroplet-Fat-Gat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRFN1 CSF1R TREM2 UNC93B1

5.14e-05162564052f797d8bcab8fc6a43e0bffdd215c88ee12889
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 LAMA3 FLG2 PRAG1

5.14e-05162564373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHANK1 NXPE4 ST18 GAB2

5.27e-051635648dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

STAB2 NXPE4 CD34 PCDH17

5.27e-05163564d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHANK1 NXPE4 ST18 GAB2

5.27e-05163564fd243ca223079033be480a24817a399f281fa4d4
ToppCelldroplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF1R TREM2 UNC93B1 ADSS1

5.39e-05164564cd0794f84dfd346807e2d803723718b7f22e9232
ToppCelldroplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF1R TREM2 UNC93B1 ADSS1

5.39e-0516456412251a49fd4af32d4edb58046245548c260cf04b
ToppCellfacs-Heart-LA-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R TREM2 UNC93B1 TNFRSF11A

5.52e-05165564be7e18d798e81e4b0f3080054aa222c6913e350b
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Myeloid|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R TREM2 UNC93B1 TNFRSF11A

5.52e-05165564518ee34c18065100a2f2c6e407d3a7866b908593
ToppCellE15.5-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CSF1R TREM2 UNC93B1 TNFRSF11A

5.52e-051655648d3d5860a4785c4908160ae5fcb421ee80bd78ce
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Myeloid-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R TREM2 UNC93B1 TNFRSF11A

5.52e-05165564becb8f726b84509ec29c75b530a3fe757651301d
ToppCellE15.5-Endothelial-lymphatic_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CSF1R TREM2 UNC93B1 TNFRSF11A

5.52e-0516556417ee6f269ed8d378465cf00ca59d48d8b106808e
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Myeloid-macrophage|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R TREM2 UNC93B1 TNFRSF11A

5.52e-05165564ae8dd9c00f96590f27ed21cd6314f4577e00e312
ToppCellfacs-Heart-LA-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R TREM2 UNC93B1 TNFRSF11A

5.52e-05165564941a5b95164eaea47c3e6376e358f94c15b98312
ToppCellBAL-Mild-Myeloid-MoAM-MoAM5-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYEOV TANC1 TMPRSS11F ST18

5.65e-05166564006ced12f69ef13ddcba5a3891ddc7c18c384863
ToppCellBAL-Mild-Myeloid-MoAM-MoAM5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYEOV TANC1 TMPRSS11F ST18

5.65e-05166564ac28c8cac1e94be0c47fb862c5809c92cdaa11f3
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SNED1 CD34 LAMA2 LAMA3

5.65e-05166564f416d8a322f086c769659a9fab6b460a2d546ab1
ToppCellBAL-Mild-Myeloid-MoAM-MoAM5-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MYEOV TANC1 TMPRSS11F ST18

5.65e-051665646bb3410e65c971acc458c472015afcec6de6e310
ToppCellBAL-Mild-Myeloid-MoAM-MoAM5|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

MYEOV TANC1 TMPRSS11F ST18

5.65e-05166564823ec03714884cb860a1260410feac8c536b6d06
ToppCellfacs-GAT-Fat-24m-Myeloid-myeloid_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R TREM2 UNC93B1 ADSS1

5.79e-051675645d9ffbcb539d9c50cef9dd792ea11aa37dd2c1df
ToppCellfacs-GAT-Fat-24m-Myeloid|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R TREM2 UNC93B1 ADSS1

5.79e-05167564c31e41fb76ba261ac546fac3cc2b8337e39bfa86
ToppCelldroplet-Heart-nan-3m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R TREM2 UNC93B1 TNFRSF11A

5.79e-0516756447447bcf184b1ad24ef17e135199fe7cd1d73c02
ToppCelldroplet-Lung-3m-Hematologic-myeloid-classical_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF1R TREM2 UNC93B1 ADSS1

5.79e-05167564d62d5dec30d006a9cc8f3bc5ccc578e10f105027
ToppCellfacs-GAT-Fat-24m-Myeloid-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R TREM2 UNC93B1 ADSS1

5.79e-05167564a04d1f2413fd24ad5e9cc67312220606157fecf3
ToppCellfacs-Thymus-nan-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHANK1 CSF1R TREM2 UNC93B1

5.92e-05168564d72cd8238fa793bb3e4add4c59eaaaadcea9930d
ToppCelldroplet-Fat-Scat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R TREM2 UNC93B1 TNFRSF11A

5.92e-05168564749eccebe4ee066f827d2a3980512f195f23ac27
ToppCellfacs-Liver-Non-hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R TREM2 UNC93B1 TNFRSF11A

5.92e-0516856495416f352801ce42cc317565e7dfb00478c593e1
ToppCellfacs-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CSF1R TREM2 UNC93B1 ADSS1

5.92e-05168564ba9ddd403ee6d6af2fe56dffbd419764bfb703e4
ToppCellfacs-Heart-RV-3m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CSF1R TREM2 UNC93B1 TNFRSF11A

5.92e-051685648ee57814c7e9d45444f48b6b269c4d535bc4d5e1
ToppCellfacs-Thymus-nan-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHANK1 CSF1R TREM2 UNC93B1

5.92e-05168564c34c52165485f612add7a3e35a175d5a6e365e7c
DrugAC1L1G72

LAMA2 LAMA3 LAMB2

2.29e-0611563CID000003553
DrugNeomycin sulfate [1405-10-3]; Down 200; 4.2uM; MCF7; HT_HG-U133A

SPHK2 STAB2 CSF1R KCNJ3 MFN2 LUZP1

8.56e-061965662229_DN
DrugIsosorbide dinitrate [87-33-2]; Up 200; 17uM; PC3; HT_HG-U133A

SPHK2 STAB2 MEGF6 CD34 TREM2 PCDH17

8.56e-061965663720_UP
Drugclozapine; Up 200; 10uM; MCF7; HT_HG-U133A

SNED1 SPHK2 ADGRG2 MFN2 LUZP1 GAB2

8.81e-061975666947_UP
DrugAC1L1B58

LAMA2 LAMA3 LAMB2

4.92e-0529563CID000001288
Drug2-[(1R,2R,3S,4R,5R,6S)-2-[(2R,5S)-3-[(3S,4S,5R,6S)-4,5-dihydroxy-3-(methylamino)-6-methylol-tetrahydropyran-2-yl]-4-formyl-4-hydroxy-5-methylol-tetrahydrofuran-2-yl]oxy-5-guanidino-3,4,6-trihydroxy-cyclohexyl]guanidine

CD34 LAMA2 LAMA3 LAMB2

5.22e-0583564CID011968896
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA

PDE3B KCNJ3 MFN2 SLC25A28 LUZP1

1.01e-041895651005_DN
Drug15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A

PCNX2 PDE3B CSF1R MFN2 TNFRSF11A

1.09e-041925657489_UP
DrugAmbroxol hydrochloride [23828-92-4]; Down 200; 9.6uM; HL60; HG-U133A

SPHK2 PDE3B JAG1 SLC25A28 LUZP1

1.09e-041925651623_DN
DrugPimozide [2062-78-4]; Up 200; 8.6uM; HL60; HG-U133A

MEGF6 JAG1 MED13L PCDH17 GAB2

1.09e-041925651562_UP
DrugOxalamine citrate salt [1949-20-8]; Up 200; 9.2uM; MCF7; HT_HG-U133A

SPHK2 PDE3B CSF1R ADGRG2 NXPE4

1.12e-041935653344_UP
DrugCalcort

LAMA2 LAMA3 LAMB2

1.12e-0438563CID000026709
DrugPapaverine hydrochloride [61-25-6]; Up 200; 10.6uM; MCF7; HT_HG-U133A

SPHK2 ADGRG2 CTC1 TNFRSF11A MED13L

1.17e-041955656245_UP
DrugMetampicillin sodium salt [6489-61-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A

PCNX2 PDE3B KCNJ3 JAG1 MFN2

1.20e-041965655540_DN
DrugNizatidine [76963-41-2]; Up 200; 12uM; MCF7; HT_HG-U133A

PCNX2 KCNJ3 TREM2 LRP4 PCDH17

1.23e-041975653385_UP
DrugCanrenoic acid potassium salt [2181-04-6]; Down 200; 10uM; MCF7; HT_HG-U133A

SPHK2 PDE3B STAB2 CSF1R LAMA3

1.23e-041975652228_DN
DrugDiprophylline [479-18-5]; Down 200; 15.8uM; MCF7; HT_HG-U133A

PDE3B ADGRG2 CTC1 LAMA3 LAMB2

1.23e-041975655482_DN
Drugrotenone; Down 200; 1uM; MCF7; HT_HG-U133A

SPHK2 CSF1R CD34 JAG1 SLC25A28

1.26e-041985655943_DN
DrugCephapirin sodium salt [24356-60-3]; Down 200; 9uM; MCF7; HT_HG-U133A

CSF1R ADGRG2 KCNJ3 JAG1 MFN2

1.26e-041985656790_DN
DrugTranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; MCF7; HT_HG-U133A

ZNF280A SNED1 PDE3B MEGF6 JAG1

1.26e-041985655996_UP
DrugRanitidine hydrochloride [66357-59-3]; Up 200; 11.4uM; MCF7; HT_HG-U133A

ZNF280A SHANK1 MEGF6 JAG1 LAMA3

1.26e-041985655425_UP
DrugJosamycin [16846-24-5]; Down 200; 4.8uM; MCF7; HT_HG-U133A

SPHK2 PDE3B KCNJ3 TNFRSF11A LUZP1

1.26e-041985651534_DN
DrugBenzocaine [94-09-7]; Up 200; 24.2uM; MCF7; HT_HG-U133A

PDE3B STAB2 JAG1 TREM2 LRP4

1.29e-041995652822_UP
Drugvalinomycin; Down 200; 0.1uM; MCF7; HT_HG-U133A

PCNX2 MEGF6 ADGRG2 LAMA2 LRP4

1.29e-041995655906_DN
DrugBumetanide [28395-03-1]; Down 200; 11uM; MCF7; HT_HG-U133A

PCNX2 PDE3B ADGRG2 KCNJ3 JAG1

1.29e-041995655542_DN
DrugCiprofloxacin hydrochloride [93107-08-5]; Down 200; 10.8uM; MCF7; HT_HG-U133A

JAG1 LAMA3 LAMB2 LUZP1 GAB2

1.32e-042005655299_DN
Diseasebone development disease (implicated_via_orthology)

CSF1R LRP4

3.54e-062562DOID:0080006 (implicated_via_orthology)
DiseaseMalignant neoplasm of salivary gland

SOX11 ISYNA1 JAG1

8.68e-0545563C0220636
DiseaseSalivary Gland Neoplasms

SOX11 ISYNA1 JAG1

9.89e-0547563C0036095
Diseasecortical thickness

SOX11 JAG1 LAMA2 LRP4 MYEOV CAMTA1 ST18 PCDH17 LUZP1

2.30e-041113569EFO_0004840
DiseaseCharcot-Marie-Tooth disease (is_implicated_in)

JAG1 MFN2

2.31e-0412562DOID:10595 (is_implicated_in)
DiseaseDementia

CSF1R TREM2

4.72e-0417562C0497327
DiseaseAdenoid Cystic Carcinoma

SOX11 ISYNA1 JAG1

9.19e-04100563C0010606
DiseaseMyasthenic Syndromes, Congenital

LRP4 LAMB2

9.51e-0424562C0751882

Protein segments in the cluster

PeptideGeneStartEntry
QGICNSSNHVQNGVT

ZNF280A

211

P59817
NGGSQAQCASGTGAL

CAMTA1

1016

Q9Y6Y1
LQGGQSPFQATASCH

CTC1

1016

Q2NKJ3
NNDCSVHASGNGNAS

ADGRG2

946

Q8IZP9
VHASGNGNASTERNG

ADGRG2

951

Q8IZP9
AQTIGNSGSANGIHQ

CLIP2

1021

Q9UDT6
SACSQPHGSVTQSQG

CHEK2

16

O96017
GCHTSFTGQGTNASE

PCDH17

831

O14917
AATNGCTGDANGHLQ

ISYNA1

536

Q9NPH2
GNIGFDCHLNGTASQ

MMADHC

76

Q9H3L0
SSCQSHRFGGQGNQF

FLG2

296

Q5D862
VCGSGQTCGQHESTS

FLG2

446

Q5D862
QSVASAGGHIAVGQQ

MED13L

296

Q71F56
QSSGQVHAFGNCSDS

LYSMD3

16

Q7Z3D4
GHSNQCQDGSGICVN

LAMA3

1691

Q16787
HVCSQTNGAGTGAAQ

LRFN1

581

Q9P244
GAQHGVSSCEGTQRT

PCNX2

1916

A6NKB5
QQIHNGCGTGNETDS

PDE3B

761

Q13370
STHSCQNGGVFQTPQ

PEAR1

231

Q5VY43
HFCSQGQHGSTSGQS

HRNR

1306

Q86YZ3
HFCSQGQHGSTSGQS

HRNR

1776

Q86YZ3
HFCSQGQHGSTSGQS

HRNR

2246

Q86YZ3
HFCSQGQHGSTSGQS

HRNR

2716

Q86YZ3
GGNSHIANGAAGCVA

SLC25A28

166

Q96A46
QGTLCGTGNRNSGSQ

MYEOV

141

Q96EZ4
SGNVSGGVCDGCQHN

LAMB2

366

P55268
NAGGSFSEVCHSQTG

LAMA2

921

P24043
GSNCSHQVQQELSGT

MFN2

681

O95140
HGNGAASVTAQARGQ

CRNKL1

101

Q9BZJ0
QHAGNYSCVASNVQG

CSF1R

271

P07333
VSAGCEVHPGNASNN

CD1D

116

P15813
LGNGSQVTQAANSGC

LUZP1

546

Q86V48
ENGTGQATSRNGHSA

CD34

361

P28906
LTNFSCHGKNGTTNG

CNOT6

446

Q9ULM6
NVANNTGPHAASCFG

CTNND1

606

O60716
NNCSHGGTCQDLVNG

JAG1

381

P78504
IVNSCEANNGGCSHG

MEGF6

331

O75095
AQGNGHCVNGISGQV

GAB2

231

Q9UQC2
QSAHSASEQQLGGGA

SOX11

371

P35716
VAAGSAGHCDGQQAL

TRMT44

546

Q8IYL2
SRCQGGNNAGHTVVV

ADSS1

61

Q8N142
GQFVNGTSQVHSECG

NXPE4

206

Q6UWF7
TSQHLGSGQSAVRNG

TANC1

1536

Q9C0D5
QNGGTCTHGINSFRC

SNED1

321

Q8TER0
GAQNASGNTALHICA

SHANK1

341

Q9Y566
GCTGRGHVNSNRNTH

ST18

416

O60284
VQFGHAGACANQASE

ACLY

756

P53396
GHKGGHNTVNQCLTA

ZNF107

56

Q9UII5
NVQSCGTNSHGILSG

UNC93B1

256

Q9H1C4
QASLQLIGSGHQCGA

TMPRSS11F

221

Q6ZWK6
CGSGNALAGAVNQHG

SPHK2

276

Q9NRA0
GTHTCVCQQGWTGNG

STAB2

891

Q8WWQ8
QSGSADGSSTNGCNH

SGSM1

516

Q2NKQ1
AAAAQGQGQVCTGNA

PRAG1

436

Q86YV5
SGAHNTTVFQGVAGQ

TREM2

16

Q9NZC2
HCGTGTAAGQEQATG

ZNFX1

871

Q9P2E3
NDILQHQGSNCGGTS

TXLNG

61

Q9NUQ3
HQGSNCGGTSNKHSL

TXLNG

66

Q9NUQ3
SVHVGQAGVQIGNAC

TUBA8

6

Q9NY65
THTANFGQQGACEGV

TNFRSF11A

271

Q9Y6Q6
GRCNVQHGNLGSETS

KCNJ3

51

P48549
QTGTNACGVNNGGCT

LRP4

1611

O75096