Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	triacylglycerol lipase activity	PLB1 PNLIP PNLIPRP1 PNLIPRP2	1.95e-06	26	70	4	GO:0004806
GeneOntologyMolecularFunction	NADH oxidase H202-forming activity	DUOX1 DUOX2	1.21e-05	2	70	2	GO:0106293
GeneOntologyMolecularFunction	NADPH oxidase H202-forming activity	DUOX1 DUOX2	1.20e-04	5	70	2	GO:0106294
GeneOntologyMolecularFunction	lipase activity	PLB1 PNLIP PNLIPRP1 PNLIPRP2 PLCL1	1.24e-04	138	70	5	GO:0016298
GeneOntologyMolecularFunction	retinyl-palmitate esterase activity	PLB1 PNLIP	4.29e-04	9	70	2	GO:0050253
GeneOntologyMolecularFunction	NAD(P)H oxidase H2O2-forming activity	DUOX1 DUOX2	7.82e-04	12	70	2	GO:0016174
GeneOntologyMolecularFunction	superoxide-generating NAD(P)H oxidase activity	DUOX1 DUOX2	7.82e-04	12	70	2	GO:0016175
GeneOntologyBiologicalProcess	cuticle development	DUOX1 DUOX2	3.40e-05	3	70	2	GO:0042335
GeneOntologyBiologicalProcess	siRNA-mediated post-transcriptional gene silencing	AGO1 AGO4	6.78e-05	4	70	2	GO:0140766
GeneOntologyBiologicalProcess	siRNA-mediated gene silencing by mRNA destabilization	AGO1 AGO4	6.78e-05	4	70	2	GO:0090625
GeneOntologyBiologicalProcess	lipid digestion	NPC1 PNLIP PNLIPRP2	7.20e-05	24	70	3	GO:0044241
GeneOntologyCellularComponent	myosin II filament	MYH9 MYH14	3.21e-05	3	69	2	GO:0097513
GeneOntologyCellularComponent	fibrillar center	METTL5 ACACA TCOF1 NFIC CEMIP	1.66e-04	156	69	5	GO:0001650
GeneOntologyCellularComponent	RISC-loading complex	AGO1 AGO4	4.75e-04	10	69	2	GO:0070578
Domain	Lipase_panc	PNLIP PNLIPRP1 PNLIPRP2	2.01e-07	4	70	3	IPR002331
Domain	Haem_peroxidase	DUOX1 LPO DUOX2	5.94e-06	10	70	3	IPR010255
Domain	An_peroxidase	DUOX1 LPO DUOX2	5.94e-06	10	70	3	PF03098
Domain	Lipase/vitellogenin	PNLIP PNLIPRP1 PNLIPRP2	5.94e-06	10	70	3	IPR013818
Domain	PEROXIDASE_3	DUOX1 LPO DUOX2	5.94e-06	10	70	3	PS50292
Domain	TAG_lipase	PNLIP PNLIPRP1 PNLIPRP2	5.94e-06	10	70	3	IPR000734
Domain	Haem_peroxidase_animal	DUOX1 LPO DUOX2	5.94e-06	10	70	3	IPR019791
Domain	Lipase_LIPH	PNLIP PNLIPRP1 PNLIPRP2	5.94e-06	10	70	3	IPR016272
Domain	Lipase	PNLIP PNLIPRP1 PNLIPRP2	5.94e-06	10	70	3	PF00151
Domain	Lipase_N	PNLIP PNLIPRP1 PNLIPRP2	5.94e-06	10	70	3	IPR033906
Domain	-	DUOX1 LPO DUOX2	5.94e-06	10	70	3	1.10.640.10
Domain	DUOX1	DUOX1 DUOX2	1.38e-05	2	70	2	IPR029595
Domain	LH2	PNLIP PNLIPRP1 PNLIPRP2	3.95e-05	18	70	3	SM00308
Domain	HYR	SRPX SVEP1	4.14e-05	3	70	2	PS50825
Domain	HYR	SRPX SVEP1	4.14e-05	3	70	2	PF02494
Domain	HYR_dom	SRPX SVEP1	4.14e-05	3	70	2	IPR003410
Domain	Sushi	PAPPA SRPX CSMD2 SVEP1	4.28e-05	52	70	4	PF00084
Domain	CCP	PAPPA SRPX CSMD2 SVEP1	4.97e-05	54	70	4	SM00032
Domain	SUSHI	PAPPA SRPX CSMD2 SVEP1	5.74e-05	56	70	4	PS50923
Domain	Sushi_SCR_CCP_dom	PAPPA SRPX CSMD2 SVEP1	6.15e-05	57	70	4	IPR000436
Domain	PLAT	PNLIP PNLIPRP1 PNLIPRP2	6.39e-05	21	70	3	PS50095
Domain	-	PNLIP PNLIPRP1 PNLIPRP2	6.39e-05	21	70	3	2.60.60.20
Domain	PLAT	PNLIP PNLIPRP1 PNLIPRP2	6.39e-05	21	70	3	PF01477
Domain	PLAT/LH2_dom	PNLIP PNLIPRP1 PNLIPRP2	6.39e-05	21	70	3	IPR001024
Domain	Argonaute_N	AGO1 AGO4	8.27e-05	4	70	2	IPR032474
Domain	Argonaute_Mid_dom	AGO1 AGO4	8.27e-05	4	70	2	IPR032473
Domain	ArgoL2	AGO1 AGO4	8.27e-05	4	70	2	IPR032472
Domain	ArgoN	AGO1 AGO4	8.27e-05	4	70	2	PF16486
Domain	ArgoMid	AGO1 AGO4	8.27e-05	4	70	2	PF16487
Domain	ArgoL2	AGO1 AGO4	8.27e-05	4	70	2	PF16488
Domain	LIPASE_SER	PNLIP PNLIPRP1 PNLIPRP2	1.23e-04	26	70	3	PS00120
Domain	DUF1785	AGO1 AGO4	1.37e-04	5	70	2	SM01163
Domain	ArgoL1	AGO1 AGO4	2.06e-04	6	70	2	PF08699
Domain	ArgoL1	AGO1 AGO4	2.06e-04	6	70	2	IPR014811
Domain	NAD_binding_6	DUOX1 DUOX2	2.87e-04	7	70	2	PF08030
Domain	FAD_binding_8	DUOX1 DUOX2	2.87e-04	7	70	2	PF08022
Domain	FAD-bd_8	DUOX1 DUOX2	2.87e-04	7	70	2	IPR013112
Domain	Fe_red_NAD-bd_6	DUOX1 DUOX2	2.87e-04	7	70	2	IPR013121
Domain	PIWI	AGO1 AGO4	3.82e-04	8	70	2	PS50822
Domain	Piwi	AGO1 AGO4	3.82e-04	8	70	2	SM00950
Domain	Piwi	AGO1 AGO4	3.82e-04	8	70	2	IPR003165
Domain	Piwi	AGO1 AGO4	3.82e-04	8	70	2	PF02171
Domain	PAZ	AGO1 AGO4	4.90e-04	9	70	2	PS50821
Domain	PAZ	AGO1 AGO4	4.90e-04	9	70	2	SM00949
Domain	PAZ_dom	AGO1 AGO4	4.90e-04	9	70	2	IPR003100
Domain	PAZ	AGO1 AGO4	4.90e-04	9	70	2	PF02170
Domain	Ferric_reduct	DUOX1 DUOX2	8.92e-04	12	70	2	PF01794
Domain	Fe3_Rdtase_TM_dom	DUOX1 DUOX2	8.92e-04	12	70	2	IPR013130
Domain	-	PNLIP PNLIPRP1 PNLIPRP2 FAM135A	1.04e-03	119	70	4	3.40.50.1820
Domain	AB_hydrolase	PNLIP PNLIPRP1 PNLIPRP2 FAM135A	1.04e-03	119	70	4	IPR029058
Domain	Myosin_N	MYH9 MYH14	1.41e-03	15	70	2	PF02736
Domain	Myosin_N	MYH9 MYH14	1.41e-03	15	70	2	IPR004009
Domain	Myosin_tail_1	MYH9 MYH14	2.04e-03	18	70	2	PF01576
Domain	Myosin_tail	MYH9 MYH14	2.04e-03	18	70	2	IPR002928
Domain	Fd_Rdtase_FAD-bd	DUOX1 DUOX2	2.27e-03	19	70	2	IPR017927
Domain	FAD_FR	DUOX1 DUOX2	2.27e-03	19	70	2	PS51384
Domain	Myosin-like_IQ_dom	MYH9 MYH14	2.27e-03	19	70	2	IPR027401
Domain	-	MYH9 MYH14	2.27e-03	19	70	2	4.10.270.10
Domain	Pyr_redox_2	ETFDH SQOR	2.27e-03	19	70	2	PF07992
Domain	Riboflavin_synthase-like_b-brl	DUOX1 DUOX2	2.27e-03	19	70	2	IPR017938
Domain	UDPGT	UGT1A4 UGT1A5	2.78e-03	21	70	2	PF00201
Domain	UDPGT	UGT1A4 UGT1A5	2.78e-03	21	70	2	PS00375
Domain	UDP_glucos_trans	UGT1A4 UGT1A5	2.78e-03	21	70	2	IPR002213
Domain	HECT	ITCH HERC2	4.57e-03	27	70	2	PF00632
Domain	HECTc	ITCH HERC2	4.57e-03	27	70	2	SM00119
Domain	HECT_dom	ITCH HERC2	4.57e-03	27	70	2	IPR000569
Domain	HECT	ITCH HERC2	4.57e-03	27	70	2	PS50237
Domain	-	NRXN1 PAPPA SVEP1	5.46e-03	95	70	3	2.60.120.200
Pathway	REACTOME_DIGESTION_OF_DIETARY_LIPID	PNLIP PNLIPRP1 PNLIPRP2	1.24e-06	6	57	3	MM14738
Pathway	REACTOME_DIGESTION_OF_DIETARY_LIPID	PNLIP PNLIPRP1 PNLIPRP2	2.17e-06	7	57	3	M27069
Pathway	REACTOME_DIGESTION	PNLIP PNLIPRP1 PNLIPRP2	7.92e-05	21	57	3	MM15526
Pathway	REACTOME_DIGESTION	PNLIP PNLIPRP1 PNLIPRP2	1.05e-04	23	57	3	M27790
Pathway	REACTOME_DIGESTION_AND_ABSORPTION	PNLIP PNLIPRP1 PNLIPRP2	1.35e-04	25	57	3	MM15557
Pathway	BIOCARTA_DICER_PATHWAY	AGO1 AGO4	1.59e-04	5	57	2	M22079
Pathway	REACTOME_DIGESTION_AND_ABSORPTION	PNLIP PNLIPRP1 PNLIPRP2	1.91e-04	28	57	3	M27837
Pathway	KEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS	UGT1A4 DHDH UGT1A5	1.91e-04	28	57	3	M19580
Pathway	REACTOME_MICRORNA_MIRNA_BIOGENESIS	AGO1 AGO4	2.38e-04	6	57	2	MM14818
Pathway	REACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS	AGO1 AGO4	2.38e-04	6	57	2	MM15083
Pathway	REACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS	AGO1 AGO4	3.33e-04	7	57	2	M46421
Pathway	REACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX	AGO1 AGO4 NR1H3	4.42e-04	37	57	3	M29790
Pathway	REACTOME_SMALL_INTERFERING_RNA_SIRNA_BIOGENESIS	AGO1 AGO4	4.43e-04	8	57	2	MM15082
Pathway	REACTOME_THYROXINE_BIOSYNTHESIS	DUOX1 DUOX2	5.68e-04	9	57	2	MM14833
Pathway	REACTOME_SMALL_INTERFERING_RNA_SIRNA_BIOGENESIS	AGO1 AGO4	5.68e-04	9	57	2	M27340
Pathway	REACTOME_REGULATION_OF_PTEN_MRNA_TRANSLATION	AGO1 AGO4	5.68e-04	9	57	2	M27810
Pathway	REACTOME_CD163_MEDIATING_AN_ANTI_INFLAMMATORY_RESPONSE	MYH9 IL6	5.68e-04	9	57	2	M29839
Pathway	REACTOME_REGULATION_OF_NPAS4_MRNA_TRANSLATION	AGO1 AGO4	5.68e-04	9	57	2	M46436
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_VENTX	AGO1 AGO4 IL6	5.99e-04	41	57	3	M29748
Pathway	REACTOME_REGULATION_OF_CDH11_MRNA_TRANSLATION_BY_MICRORNAS	AGO1 AGO4	7.08e-04	10	57	2	M48013
Pathway	REACTOME_THYROXINE_BIOSYNTHESIS	DUOX1 DUOX2	7.08e-04	10	57	2	M27120
Pathway	REACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING	AGO1 AGO4 NR1H3	8.96e-04	47	57	3	M29777
Pathway	KEGG_GLYCEROLIPID_METABOLISM	PNLIP PNLIPRP1 PNLIPRP2	1.01e-03	49	57	3	M15902
Pathway	REACTOME_REGULATION_OF_NPAS4_GENE_EXPRESSION	AGO1 AGO4	1.22e-03	13	57	2	M46434
Pubmed	Pancreatic lipase and its related proteins: where are we now?	PNLIP PNLIPRP1 PNLIPRP2	8.15e-09	3	71	3	38081381
Pubmed	Two novel human pancreatic lipase related proteins, hPLRP1 and hPLRP2. Differences in colipase dependence and in lipase activity.	PNLIP PNLIPRP1 PNLIPRP2	8.15e-09	3	71	3	1379598
Pubmed	Cloning of an interleukin-4 inducible gene from cytotoxic T lymphocytes and its identification as a lipase.	PNLIP PNLIPRP1 PNLIPRP2	8.15e-09	3	71	3	2302735
Pubmed	Role of nicotinamide adenine dinucleotide phosphate oxidase in mediating vesicant-induced interleukin-6 secretion in human airway epithelial cells.	DUOX1 DUOX2 IL6	8.15e-09	3	71	3	24164541
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	MYH9 ACACA MYH14 CKAP5 EIF5B HERC2	3.73e-06	202	71	6	33005030
Pubmed	Digenic DUOX1 and DUOX2 Mutations in Cases With Congenital Hypothyroidism.	DUOX1 DUOX2	4.11e-06	2	71	2	28633507
Pubmed	The Importance of AGO 1 and 4 in Post-Transcriptional Gene Regulatory Function of tRF5-GluCTC, an Respiratory Syncytial Virus-Induced tRNA-Derived RNA Fragment.	AGO1 AGO4	4.11e-06	2	71	2	33233493
Pubmed	Reactive oxygen species regulate the levels of dual oxidase (Duox1-2) in human neuroblastoma cells.	DUOX1 DUOX2	4.11e-06	2	71	2	22523549
Pubmed	Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis.	DUOX1 DUOX2	4.11e-06	2	71	2	23281318
Pubmed	Dual oxidase 1 and NADPH oxidase 2 exert favorable effects in cervical cancer patients by activating immune response.	DUOX1 DUOX2	4.11e-06	2	71	2	31706280
Pubmed	Kinetic properties of mouse pancreatic lipase-related protein-2 suggest the mouse may not model human fat digestion.	PNLIP PNLIPRP2	4.11e-06	2	71	2	21382969
Pubmed	Dual oxidase-2 has an intrinsic Ca2+-dependent H2O2-generating activity.	DUOX1 DUOX2	4.11e-06	2	71	2	15972824
Pubmed	Conserved cysteine residues provide a protein-protein interaction surface in dual oxidase (DUOX) proteins.	DUOX1 DUOX2	4.11e-06	2	71	2	23362256
Pubmed	Activation of dual oxidases Duox1 and Duox2: differential regulation mediated by camp-dependent protein kinase and protein kinase C-dependent phosphorylation.	DUOX1 DUOX2	4.11e-06	2	71	2	19144650
Pubmed	Expression of nicotinamide adenine dinucleotide phosphate oxidase flavoprotein DUOX genes and proteins in human papillary and follicular thyroid carcinomas.	DUOX1 DUOX2	4.11e-06	2	71	2	11762710
Pubmed	Characterization of ThOX proteins as components of the thyroid H(2)O(2)-generating system.	DUOX1 DUOX2	4.11e-06	2	71	2	11822874
Pubmed	Dual oxidase 1 and 2 expression in airway epithelium of smokers and patients with mild/moderate chronic obstructive pulmonary disease.	DUOX1 DUOX2	4.11e-06	2	71	2	18177232
Pubmed	Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense.	DUOX1 DUOX2	4.11e-06	2	71	2	12824283
Pubmed	Congenital Hypothyroidism due to Oligogenic Mutations in Two Sudanese Families.	DUOX1 DUOX2	4.11e-06	2	71	2	30375286
Pubmed	Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family.	DUOX1 DUOX2	4.11e-06	2	71	2	10806195
Pubmed	Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox.	DUOX1 DUOX2	4.11e-06	2	71	2	11514595
Pubmed	Roles of DUOX-mediated hydrogen peroxide in metabolism, host defense, and signaling.	DUOX1 DUOX2	4.11e-06	2	71	2	24161126
Pubmed	Expression of reduced nicotinamide adenine dinucleotide phosphate oxidase (ThoX, LNOX, Duox) genes and proteins in human thyroid tissues.	DUOX1 DUOX2	4.11e-06	2	71	2	11443211
Pubmed	Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cdnas.	DUOX1 DUOX2	4.11e-06	2	71	2	10601291
Pubmed	The extracellular A-loop of dual oxidases affects the specificity of reactive oxygen species release.	DUOX1 DUOX2	4.11e-06	2	71	2	25586178
Pubmed	Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium.	DUOX1 DUOX2	4.11e-06	2	71	2	16111680
Pubmed	Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases.	DUOX1 DUOX2	4.11e-06	2	71	2	11753072
Pubmed	Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer.	DUOX1 DUOX2	4.11e-06	2	71	2	18281478
Pubmed	Structural and functional characterization of the two human ThOX/Duox genes and their 5'-flanking regions.	DUOX1 DUOX2	4.11e-06	2	71	2	15062544
Pubmed	Distinct roles of nonmuscle myosin II isoforms for establishing tension and elasticity during cell morphodynamics.	MYH9 MYH14	4.11e-06	2	71	2	34374341
Pubmed	Regulated hydrogen peroxide production by Duox in human airway epithelial cells.	DUOX1 DUOX2	4.11e-06	2	71	2	15677770
Pubmed	Effects of Echinococcus multilocularis miR-71 mimics on murine macrophage RAW264.7 cells.	AGO1 AGO4	4.11e-06	2	71	2	26995025
Pubmed	Mucosal reactive oxygen species are required for antiviral response: role of Duox in influenza a virus infection.	DUOX1 DUOX2	4.11e-06	2	71	2	24128054
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	NRXN1 CKAP5 MAGI3 DSCAML1 CEMIP	7.22e-06	130	71	5	12421765
Pubmed	GPR43 activation enhances psoriasis-like inflammation through epidermal upregulation of IL-6 and dual oxidase 2 signaling in a murine model.	DUOX2 IL6	1.23e-05	3	71	2	28212864
Pubmed	Integration of metabolomics and transcriptomics revealed a fatty acid network exerting growth inhibitory effects in human pancreatic cancer.	PNLIP PNLIPRP1	1.23e-05	3	71	2	23918603
Pubmed	A Hypoxia Molecular Signature-Based Prognostic Model for Endometrial Cancer Patients.	SRPX IL6	1.23e-05	3	71	2	36675190
Pubmed	Planar polarity of multiciliated ependymal cells involves the anterior migration of basal bodies regulated by non-muscle myosin II.	MYH9 MYH14	1.23e-05	3	71	2	20685736
Pubmed	NADPH oxidase DUOX1 and DUOX2 but not NOX4 are independent predictors in hepatocellular carcinoma after hepatectomy.	DUOX1 DUOX2	1.23e-05	3	71	2	21915726
Pubmed	Correlation between the clinical phenotype of MYH9-related disease and tissue distribution of class II nonmuscle myosin heavy chains.	MYH9 MYH14	1.23e-05	3	71	2	15177565
Pubmed	Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins.	AGO1 AGO4	1.23e-05	3	71	2	19946268
Pubmed	Vertebrate nonmuscle myosin II isoforms rescue small interfering RNA-induced defects in COS-7 cell cytokinesis.	MYH9 MYH14	1.23e-05	3	71	2	15774463
Pubmed	NADPH oxidase-dependent acid production in airway epithelial cells.	DUOX1 DUOX2	1.23e-05	3	71	2	15210697
Pubmed	DUOX enzyme activity promotes AKT signalling in prostate cancer cells.	DUOX1 DUOX2	1.23e-05	3	71	2	23225414
Pubmed	Elevated Serum Levels of sCD30 and IL6 and Detectable IL10 Precede Classical Hodgkin Lymphoma Diagnosis.	TNFRSF8 IL6	1.23e-05	3	71	2	28341757
Pubmed	Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family.	MYH9 MYH14	1.23e-05	3	71	2	14594953
Pubmed	Endosomal accumulation of Toll-like receptor 4 causes constitutive secretion of cytokines and activation of signal transducers and activators of transcription in Niemann-Pick disease type C (NPC) fibroblasts: a potential basis for glial cell activation in the NPC brain.	NPC1 IL6	1.23e-05	3	71	2	17314284
Pubmed	Characterization of three full-length human nonmuscle myosin II paralogs.	MYH9 MYH14	1.23e-05	3	71	2	24072716
Pubmed	Association of duoxes with thyroid peroxidase and its regulation in thyrocytes.	DUOX1 DUOX2	1.23e-05	3	71	2	19952225
Pubmed	Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C.	MYH9 MYH14	1.23e-05	3	71	2	15845534
Pubmed	Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice.	DUOX1 DUOX2 PAPPA	2.05e-05	26	71	3	33905568
Pubmed	Molecular dissection of human Argonaute proteins by DNA shuffling.	AGO1 AGO4	2.46e-05	4	71	2	23748378
Pubmed	Genetic variations and haplotypes of UDP-glucuronosyltransferase 1A locus in a Korean population.	UGT1A4 UGT1A5	2.46e-05	4	71	2	18223459
Pubmed	Immunoexpression of the CD30 ligand/CD30 and IL-6/IL-6R signals in thyroid autoimmune diseases.	TNFRSF8 IL6	2.46e-05	4	71	2	16372246
Pubmed	Targeted disruption of the idol gene alters cellular regulation of the low-density lipoprotein receptor by sterols and liver x receptor agonists.	ITCH NR1H3	2.46e-05	4	71	2	21343340
Pubmed	MIG12 is involved in the LXR activation-mediated induction of the polymerization of mammalian acetyl-CoA carboxylase.	ACACA NR1H3	2.46e-05	4	71	2	34153683
Pubmed	Slicing-independent RISC activation requires the argonaute PAZ domain.	AGO1 AGO4	2.46e-05	4	71	2	22795694
Pubmed	Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages.	NPC1 NR1H3	2.46e-05	4	71	2	16141411
Pubmed	The type of DUOX-dependent ROS production is dictated by defined sequences in DUOXA.	DUOX1 DUOX2	2.46e-05	4	71	2	22814254
Pubmed	Importance of translation and nonnucleolytic ago proteins for on-target RNA interference.	AGO1 AGO4	2.46e-05	4	71	2	18771919
Pubmed	Cellular nonmuscle myosins NMHC-IIA and NMHC-IIB and vertebrate heart looping.	MYH9 MYH14	2.46e-05	4	71	2	18697221
Pubmed	Nox4 and Duox1/2 Mediate Redox Activation of Mesenchymal Cell Migration by PDGF.	DUOX1 DUOX2	2.46e-05	4	71	2	27110716
Pubmed	Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs.	AGO1 AGO4	2.46e-05	4	71	2	15260970
Pubmed	Co-expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) in thyroid nodules is associated with co-expression of CD30 ligand/CD30 receptor.	TNFRSF8 IL6	2.46e-05	4	71	2	12553555
Pubmed	CD30 contains two binding sites with different specificities for members of the tumor necrosis factor receptor-associated factor family of signal transducing proteins.	TRAF3 TNFRSF8	2.46e-05	4	71	2	8662842
Pubmed	Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells.	DUOX1 DUOX2	2.46e-05	4	71	2	19339556
Pubmed	ATP-dependent human RISC assembly pathways.	AGO1 AGO4	2.46e-05	4	71	2	19966796
Pubmed	Liver X receptor regulates rheumatoid arthritis fibroblast-like synoviocyte invasiveness, matrix metalloproteinase 2 activation, interleukin-6 and CXCL10.	NR1H3 IL6	2.46e-05	4	71	2	22634718
Pubmed	A Requirement for Argonaute 4 in Mammalian Antiviral Defense.	AGO1 AGO4	2.46e-05	4	71	2	32049003
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TRAF3 MYH9 ITCH AGO1 NRXN1 TCOF1 CKAP5 LMO3 PLCL1 HERC2	2.53e-05	963	71	10	28671696
Pubmed	Myosin II regulates extension, growth and patterning in the mammalian cochlear duct.	MYH9 MYH14	4.09e-05	5	71	2	19439495
Pubmed	Differential expression of Dicer and Argonaute genes during the differentiation of human neuroblastoma cells.	AGO1 AGO4	4.09e-05	5	71	2	19393748
Pubmed	Multiscale analysis of single and double maternal-zygotic Myh9 and Myh10 mutants during mouse preimplantation development.	MYH9 MYH14	4.09e-05	5	71	2	33871354
Pubmed	The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis.	AGO1 AGO4	4.09e-05	5	71	2	12414724
Pubmed	Expression of TPO and ThOXs in human thyrocytes is downregulated by IL-1alpha/IFN-gamma, an effect partially mediated by nitric oxide.	DUOX1 DUOX2	4.09e-05	5	71	2	16478776
Pubmed	The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing.	AGO1 AGO4	4.09e-05	5	71	2	19324964
Pubmed	Morphogenesis and Compartmentalization of the Intestinal Crypt.	MYH9 MYH14	4.09e-05	5	71	2	29689194
Pubmed	Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors.	AGO1 AGO4	4.09e-05	5	71	2	12526743
Pubmed	Activation of liver X receptors promotes inflammatory cytokine mRNA degradation by upregulation of tristetraprolin.	NR1H3 IL6	4.09e-05	5	71	2	28119310
Pubmed	Cell-cell adhesions and cell contractility are upregulated upon desmosome disruption.	MYH9 MYH14	4.09e-05	5	71	2	25006807
Pubmed	Identification of a novel partner of duox: EFP1, a thioredoxin-related protein.	DUOX1 DUOX2	4.09e-05	5	71	2	15561711
Pubmed	The adaptor protein TRAF3 inhibits interleukin-6 receptor signaling in B cells to limit plasma cell development.	TRAF3 IL6	4.09e-05	5	71	2	26329582
Pubmed	Differential expression of components of the microRNA machinery during mouse organogenesis.	AGO1 AGO4	4.09e-05	5	71	2	16036130
Pubmed	Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca2+ signaling during T cell activation.	DUOX1 DUOX2	4.09e-05	5	71	2	34784249
Pubmed	The Gastric Mucosa from Patients Infected with CagA+ or VacA+ Helicobacter pylori Has a Lower Level of Dual Oxidase-2 Expression than Uninfected or Infected with CagA-/VacA- H. pylori.	LPO DUOX2	4.09e-05	5	71	2	27048452
Pubmed	The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis.	PNLIP PNLIPRP1 CPB1	5.55e-05	36	71	3	25063451
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	NPC1 DLC1 PNLIPRP1 PNLIPRP2 GLRX3 NFIC POLB CKAP5 NR1H3 PLCL1 PRIMPOL	5.94e-05	1293	71	11	15342556
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	NPC1 MYH9 TCOF1 MYH14 EIF5B	6.00e-05	202	71	5	24639526
Pubmed	Nonmuscle myosin II regulation of lung epithelial morphology.	MYH9 MYH14	6.13e-05	6	71	2	22972683
Pubmed	A point mutation in the motor domain of nonmuscle myosin II-B impairs migration of distinct groups of neurons.	MYH9 MYH14	6.13e-05	6	71	2	15034141
Pubmed	Duox expression and related H2O2 measurement in mouse thyroid: onset in embryonic development and regulation by TSH in adult.	DUOX1 DUOX2	6.13e-05	6	71	2	17332529
Pubmed	APX-115, a first-in-class pan-NADPH oxidase (Nox) inhibitor, protects db/db mice from renal injury.	DUOX1 DUOX2	6.13e-05	6	71	2	28165467
Pubmed	Replacing nonmuscle myosin 2A with myosin 2C1 permits gastrulation but not placenta vascular development in mice.	MYH9 MYH14	6.13e-05	6	71	2	30044719
Pubmed	Gatm, a creatine synthesis enzyme, is imprinted in mouse placenta.	DUOX1 DUOX2	6.13e-05	6	71	2	12671064
Pubmed	Binding sites of cytoplasmic effectors TRAF1, 2, and 3 on CD30 and other members of the TNF receptor superfamily.	TRAF3 TNFRSF8	6.13e-05	6	71	2	9168896
Pubmed	Assignment of the mouse vesicular monoamine transporter genes, Slc18a1 and Slc18a2, to chromosomes 8 and 19 by linkage analysis.	PNLIP PNLIPRP1	6.13e-05	6	71	2	8661734
Pubmed	Assignment of Gpam to distal mouse chromosome 19 by linkage analysis.	PNLIP PNLIPRP1	6.13e-05	6	71	2	9434961
Pubmed	MST4 negatively regulates type I interferons production via targeting MAVS-mediated pathway.	TRAF3 ITCH	6.13e-05	6	71	2	35820905
Pubmed	Assignment of the human UDP glucuronosyltransferase gene (UGT1A1) to chromosome region 2q37.	UGT1A4 UGT1A5	8.57e-05	7	71	2	8467709
Pubmed	Genome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development.	AGO1 AGO4	8.57e-05	7	71	2	34907157
Cytoband	15q15.3	DUOX1 DUOX2	6.91e-04	25	71	2	15q15.3
Cytoband	10q25.3	PNLIPRP1 PNLIPRP2	9.32e-04	29	71	2	10q25.3
Cytoband	2q37	UGT1A4 UGT1A5	1.07e-03	31	71	2	2q37
Cytoband	Ensembl 112 genes in cytogenetic band chr10q25	PNLIP PNLIPRP1 PNLIPRP2	1.13e-03	131	71	3	chr10q25
Cytoband	8p22	ZDHHC2 DLC1	1.77e-03	40	71	2	8p22
Cytoband	Ensembl 112 genes in cytogenetic band chr8p22	ZDHHC2 DLC1	2.44e-03	47	71	2	chr8p22
Cytoband	Ensembl 112 genes in cytogenetic band chr15q21	DUOX1 DUOX2 SQOR	2.66e-03	177	71	3	chr15q21
Cytoband	1p34.3	AGO1 CSMD2	4.20e-03	62	71	2	1p34.3
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	PAPPA SRPX CSMD2 SVEP1	1.20e-05	57	45	4	1179
GeneFamily	Argonaute/PIWI family	AGO1 AGO4	1.68e-04	8	45	2	408
GeneFamily	Myosin heavy chains	MYH9 MYH14	6.23e-04	15	45	2	1098
GeneFamily	Lipases\|Arylacetamide deacetylase family	PNLIP PNLIPRP2	1.36e-03	22	45	2	464
GeneFamily	Actins\|Deafness associated genes	MYH9 GSDME MYH14	2.79e-03	113	45	3	1152
GeneFamily	UDP glucuronosyltransferases	UGT1A4 UGT1A5	2.87e-03	32	45	2	363
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	DUOX1 SGMS2 DLC1 ACACA NIM1K MAGI3 LMO3	1.56e-08	180	71	7	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BMP3 MYH14 NIM1K MAGI3 LMO3 SLC44A3	5.11e-07	185	71	6	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	droplet-Pancreas\|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNLIP PNLIPRP1 PNLIPRP2 NRXN1 CPB1 UNC80	5.44e-07	187	71	6	5f4df092452d8672bda4059c794e099ba3f5a8fa
ToppCell	Control-Epithelial_cells\|Control / group, cell type (main and fine annotations)	DUOX1 SGMS2 DLC1 MYH14 MAGI3 LMO3	5.62e-07	188	71	6	707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NPC1 DUOX1 DLC1 ACACA MAGI3 LMO3	6.16e-07	191	71	6	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DUOX1 DLC1 ACACA MYH14 MAGI3 LMO3	6.16e-07	191	71	6	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	DUOX1 DLC1 ACACA MYH14 MAGI3 LMO3	6.35e-07	192	71	6	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	Adult-Epithelial\|Adult / Lineage, Cell type, age group and donor	DUOX1 DLC1 ACACA MYH14 MAGI3 LMO3	6.35e-07	192	71	6	efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DUOX1 SGMS2 DLC1 ACACA MAGI3 LMO3	6.55e-07	193	71	6	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DUOX1 SGMS2 DLC1 ACACA MAGI3 LMO3	6.55e-07	193	71	6	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DUOX1 DLC1 ACACA MYH14 MAGI3 LMO3	6.75e-07	194	71	6	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DUOX1 DLC1 ACACA MYH14 MAGI3 LMO3	6.95e-07	195	71	6	9406866f99555198a9be311fbd65751b70f35446
ToppCell	Control_saline-Epithelial_alveolar-AT_2\|Control_saline / Treatment groups by lineage, cell group, cell type	BMP3 MYH14 NIM1K CCDC190 LMO3 SLC44A3	7.38e-07	197	71	6	b8f62fcd6eb8f47b3cc41f616126f82c68a36e87
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DUOX1 DLC1 ACACA MYH14 MAGI3 LMO3	7.83e-07	199	71	6	725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DUOX1 DLC1 ACACA MYH14 MAGI3 LMO3	7.83e-07	199	71	6	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	control-B_cell\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	GLRA3 SRPX CSMD2 UNC80 SLC44A3	1.93e-06	128	71	5	24abab941b4a2f89e13089d208d40ec02f0cad10
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNLIP PNLIPRP1 PNLIPRP2 CPB1	4.82e-06	70	71	4	26178ee967d647224d93c7a6380f2d15d8fcfb8f
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNLIP PNLIPRP1 PNLIPRP2 CPB1	4.82e-06	70	71	4	5720505ef03d65c73028616c808420e282823bde
ToppCell	facs-MAT-Fat-24m-Epithelial-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP3 PNLIP PNLIPRP1 PNLIPRP2 CPB1	5.25e-06	157	71	5	30814ff90cead688ef64dac4cf4a6d63756d8944
ToppCell	facs-MAT-Fat-24m-Epithelial\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP3 PNLIP PNLIPRP1 PNLIPRP2 CPB1	5.25e-06	157	71	5	a47d102570e82d34ea1a8756f82636e7ab27c07f
ToppCell	facs-MAT-Fat-24m-Epithelial-epithelial_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP3 PNLIP PNLIPRP1 PNLIPRP2 CPB1	5.25e-06	157	71	5	7c20f225b2db8b340f4fec050ff29e666b860f04
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLB1 GLRA3 DSCAML1 SVEP1 UNC80	5.75e-06	160	71	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLB1 GLRA3 DSCAML1 SVEP1 UNC80	5.75e-06	160	71	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP3 PNLIP PNLIPRP1 PNLIPRP2 CPB1	6.68e-06	165	71	5	622aca1d49bd8c917b131e4f4959d9dba411d22b
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ACACA MYH14 MAGI3 LMO3 PLCL1	9.66e-06	178	71	5	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SGMS2 ADAMTS18 PAPPA SRPX SVEP1	9.66e-06	178	71	5	e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPC1 ADAMTS18 MAGI3 PLCL1 DSCAML1	9.92e-06	179	71	5	e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCell	COVID-19-Epithelial_cells-AT1\|COVID-19 / group, cell type (main and fine annotations)	DUOX1 MYH14 MAGI3 LMO3 SLC44A3	9.92e-06	179	71	5	a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SGMS2 MYH14 MAGI3 DSCAML1 SLC44A3	9.92e-06	179	71	5	04ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CNNM2 PPM1E ADAMTS18 MAGI3 PLCL1	1.02e-05	180	71	5	cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DLC1 PAPPA SRPX IL6 SVEP1	1.05e-05	181	71	5	ab66a89f316b935d9ba1277426d976b1e9e39757
ToppCell	Control-Epithelial_alveolar-AT_2-AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BMP3 MYH14 NIM1K LMO3 SLC44A3	1.08e-05	182	71	5	e97681a4102f3095d5d9e90ad70f1dc46e90983a
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DUOX1 DLC1 ACACA MAGI3 LMO3	1.10e-05	183	71	5	6847c1252d6bb105524f812658112517fd351eab
ToppCell	COVID-19-lung-AT1\|lung / Disease (COVID-19 only), tissue and cell type	DUOX1 MYH14 MAGI3 LMO3 SLC44A3	1.10e-05	183	71	5	942530449e9c6583705eeb8f6f12621daea57252
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1-AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BMP3 MYH14 NIM1K LMO3 SLC44A3	1.10e-05	183	71	5	06ac66726ec53db810ebb90ec69cfdb903da53f6
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CNNM2 NRXN1 ADAMTS18 SRPX PLCL1	1.13e-05	184	71	5	689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCell	Control-Epithelial_alveolar-AT_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BMP3 MYH14 NIM1K LMO3 SLC44A3	1.13e-05	184	71	5	51e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCell	Control-Epithelial_alveolar-AT_2-AT2_Progenitor\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BMP3 MYH14 NIM1K CCDC190 LMO3	1.16e-05	185	71	5	8ca1374501eca01d8468130b74d50abfd4329fbe
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	DUOX1 ACACA MYH14 MAGI3 LMO3	1.16e-05	185	71	5	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	DLC1 PAPPA SRPX SVEP1 CEMIP	1.16e-05	185	71	5	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BMP3 MYH14 MAGI3 LMO3 SLC44A3	1.19e-05	186	71	5	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PNLIP LMO3 CPB1 SRPX SVEP1	1.19e-05	186	71	5	7582b5154d8e5a4434817b5ab77a10b789ea2288
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	ACACA MYH14 MAGI3 LMO3 PLCL1	1.23e-05	187	71	5	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	15-Distal-Epithelial-Secretory_progenitor\|Distal / Age, Tissue, Lineage and Cell class	BMP3 MYH14 MAGI3 LMO3 SLC44A3	1.26e-05	188	71	5	9a64fb07de611de38d6f24673feb3b81a5e85384
ToppCell	COVID-19-lung-AT2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DUOX1 ACACA MYH14 MAGI3 LMO3	1.32e-05	190	71	5	27a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	BMP3 SGMS2 MYH14 LMO3 SLC44A3	1.36e-05	191	71	5	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	DUOX1 ACACA MYH14 MAGI3 LMO3	1.36e-05	191	71	5	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	DLC1 MYH14 MAGI3 LMO3 SLC44A3	1.36e-05	191	71	5	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAPPA CPB1 SRPX IL6 SVEP1	1.39e-05	192	71	5	9479e9859140ba98abfe88414de0b28fc2bf43b7
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	DUOX1 DLC1 ACACA MAGI3 LMO3	1.39e-05	192	71	5	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DUOX1 MAGI3 LMO3 PLCL1 SLC44A3	1.39e-05	192	71	5	29f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	DUOX1 DLC1 ACACA NIM1K LMO3	1.39e-05	192	71	5	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAPPA CPB1 SRPX IL6 SVEP1	1.39e-05	192	71	5	d7faa993f68e530ad55185505384ae155d36c222
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMP3 SGMS2 DLC1 MAGI3 LMO3	1.46e-05	194	71	5	db06ae2dba45640da329a4d0d94973ac9dda7729
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMP3 SGMS2 DLC1 MAGI3 LMO3	1.46e-05	194	71	5	d3f5cd6c40354bfe86348bb0e82697a939759625
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMP3 SGMS2 DLC1 MAGI3 LMO3	1.46e-05	194	71	5	d4f4036b650a27312283fa8851f3975595cc2d3f
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-epithelial_cell_of_lung\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BMP3 SGMS2 DLC1 MAGI3 LMO3	1.46e-05	194	71	5	4974c208e6ee37a51cd95a61d48b26c5de416992
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NPC1 DUOX1 SGMS2 DLC1 ACACA	1.46e-05	194	71	5	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	LA-14._Fibroblast_III\|World / Chamber and Cluster_Paper	PAPPA LMO3 SRPX IL6 SVEP1	1.46e-05	194	71	5	803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	BMP3 SGMS2 MYH14 LMO3 SLC44A3	1.46e-05	194	71	5	f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LMO3 CPB1 SRPX IL6 SVEP1	1.50e-05	195	71	5	fc43cd295f2cc3f6e9442232e028944f011c82cc
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DUOX1 ACACA MAGI3 LMO3 PLCL1	1.54e-05	196	71	5	ed76eeb37400ca154feae9b7ebaddb6c434f8b81
ToppCell	5'-Adult-Appendix\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DLC1 LMO3 SRPX IL6 SVEP1	1.54e-05	196	71	5	a579211ef14f348d0c5a290553150222dfbf1515
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PLB1 PNLIPRP1 MYH14 CSMD2 SLC44A3	1.58e-05	197	71	5	b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DLC1 SRPX CSMD2 MYL10 SVEP1	1.58e-05	197	71	5	0dd71e399f253787fa546a7e90c5373180b89ffd
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAPPA LMO3 CPB1 SRPX SVEP1	1.58e-05	197	71	5	ab5d3ebc73bd7cfc64381d14b92878b370205186
ToppCell	5'-Adult-Appendix-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAPPA LMO3 CPB1 SRPX SVEP1	1.58e-05	197	71	5	b11a5d909942a4299cbc0b27332b1a3f66f3bccd
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	DLC1 PAPPA CSMD2 SVEP1 CEMIP	1.58e-05	197	71	5	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	Control_saline-Epithelial_alveolar-AT_2-AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	BMP3 MYH14 NIM1K LMO3 SLC44A3	1.58e-05	197	71	5	f870a26f322668781e3d2832c5d9ef2c7c91011f
ToppCell	3'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DLC1 LMO3 CPB1 SRPX SVEP1	1.61e-05	198	71	5	abac765c4f6864bdb1700bc546c3b9771edc25c3
ToppCell	3'-Adult-LymphNode-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DLC1 LMO3 CPB1 SRPX SVEP1	1.61e-05	198	71	5	ff57addcbdd53e5d2d0c80ec76b5eab3b3a67ca2
ToppCell	3'-Adult-LymphNode-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DLC1 LMO3 CPB1 SRPX SVEP1	1.61e-05	198	71	5	698166b4ca173176ed563af6a1efc8c7d0a18e0b
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DUOX1 ACACA MYH14 MAGI3 LMO3	1.65e-05	199	71	5	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DUOX1 ACACA MYH14 MAGI3 LMO3	1.65e-05	199	71	5	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	Biopsy_Control_(H.)-Epithelial-Transitional_AT2\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	DUOX1 DLC1 MYH14 MAGI3 LMO3	1.65e-05	199	71	5	e04a57a55c724091db353e2b3baf84372d788728
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_only / Treatment groups by lineage, cell group, cell type	CNNM2 DLC1 ADAMTS18 SRPX PLCL1	1.69e-05	200	71	5	69edc375d85689300d1dbc1217fedc40063ecdcb
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNLIP PNLIPRP1 PNLIPRP2 CPB1	1.77e-05	97	71	4	16947da747504c2edb9f2e7ee6f05babda0fae60
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNLIP PNLIPRP1 PNLIPRP2 CPB1	2.50e-05	106	71	4	3aa55c3db4e4abd39c8f2f89f2516927d94ad9d7
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNLIP PNLIPRP1 PNLIPRP2 CPB1	2.50e-05	106	71	4	c890c838785dfeda30f3b563194da9cfb49b157a
ToppCell	LPS_only-Unknown-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NRXN1 PPM1E APOL5 CSMD2	3.45e-05	115	71	4	ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCell	LPS_only-Unknown\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NRXN1 PPM1E APOL5 CSMD2	3.45e-05	115	71	4	7a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCell	LPS_only-Unknown-Endothelial-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NRXN1 PPM1E APOL5 CSMD2	3.45e-05	115	71	4	c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCell	COVID-19-kidney-Epithelial_Doublet\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRXN1 NEUROD4 MYL10 DSCAML1	5.57e-05	130	71	4	1ff28e9d3dc9a791e07d815f8fbb48f75d3f275b
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BMP3 MYH14 MAGI3 LMO3	5.57e-05	130	71	4	6434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNLIP PNLIPRP1 PNLIPRP2 CPB1	6.08e-05	133	71	4	91e4556658e49f92946d48b194df64c5fc5758fe
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFIC UGT1A5 NIM1K SRPX	7.42e-05	140	71	4	e442c46979d725ec82f525a001c46d971fcade4d
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNLIP PNLIPRP1 MYH14 CPB1	9.95e-05	151	71	4	a306e8dac653bc785d805d8d2d94feec3cb01727
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNLIP PNLIPRP1 PNLIPRP2 CPB1	1.05e-04	153	71	4	39ac25c48e73538f1c10f37bea386e0e88d3e8d0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PNLIP MYH14 PAPPA LMO3	1.10e-04	155	71	4	29c4e9947bb4f7e257ed5c3bcf21bd67f88d473f
ToppCell	facs-MAT-Fat-24m\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMP3 PNLIP PNLIPRP1 CPB1	1.13e-04	156	71	4	7433c6d4eb4d061844d8979c1e648d8ed56e1073
ToppCell	control-B_cell\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	GLRA3 SRPX UNC80 SLC44A3	1.16e-04	157	71	4	1269b55f2ef6a493f6116b131cc5cc7b8897d63e
ToppCell	facs-Heart-Unknown-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZDHHC2 MYH14 UGT1A5 SLC44A3	1.16e-04	157	71	4	8d30d8e6fae93afcada6bd68799439335cd65b69
ToppCell	facs-Heart-Unknown-3m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZDHHC2 MYH14 UGT1A5 SLC44A3	1.16e-04	157	71	4	2ac4695d9e4ca8d4ba19c555e9a1d86ac8f398ab
ToppCell	facs-Heart-Unknown-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZDHHC2 MYH14 UGT1A5 SLC44A3	1.16e-04	157	71	4	8a393eece90fb9a1b7c356736bdb36277261fbd3
ToppCell	droplet-Spleen-nan-24m-Myeloid-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGMS2 GSDME NR1H3 SQOR	1.18e-04	158	71	4	e1a8dba5a88bc3ce112829c5ecb112cbbee5b078
ToppCell	droplet-Spleen-nan-24m-Myeloid\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGMS2 GSDME NR1H3 SQOR	1.18e-04	158	71	4	72e4f8ae137a7dddee0dc6236532e0711065e6af
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DLC1 NIM1K SVEP1 CEMIP	1.21e-04	159	71	4	e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DLC1 NIM1K SVEP1 CEMIP	1.21e-04	159	71	4	2607b562903228274fbd96168ba826782fab0b53
ToppCell	Control-APC-like-Monocyte-derived_macrophages\|Control / group, cell type (main and fine annotations)	PLB1 PPM1E GLRA3 NR1H3	1.24e-04	160	71	4	463dd624ca5c375b6ff7c269f4ef4b9d74f4b669
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNLIP PNLIPRP1 PNLIPRP2 CPB1	1.27e-04	161	71	4	b9a17f41426bf715f30bf544a6795afaf37a3aa6
Computational	Neighborhood of SERPINI2	PNLIP PNLIPRP1 PNLIPRP2 CPB1	3.18e-06	25	45	4	GNF2_SERPINI2
Computational	Neighborhood of SPINK1	PNLIP PNLIPRP1 PNLIPRP2 CPB1	4.38e-06	27	45	4	GNF2_SPINK1
Drug	Austricine [10180-88-8]; Up 200; 14.2uM; MCF7; HT_HG-U133A	DLC1 AGO4 MYH14 TNFRSF8 PAPPA CPB1 POFUT1 MYL10 SVEP1	1.06e-08	197	71	9	2812_UP
Drug	sulfoquinovosyldiacylglycerol	PNLIP PNLIPRP1 PNLIPRP2 POLB	2.00e-07	17	71	4	CID000448048
Drug	SQDG	PNLIP PNLIPRP1 PNLIPRP2 POLB	8.80e-07	24	71	4	CID006475552
Drug	capecitabine	UGT1A4 PLB1 PNLIP PNLIPRP1 PNLIPRP2 UGT1A5	8.84e-07	104	71	6	CID000060953
Drug	tripropionin	PNLIP PNLIPRP1 PNLIPRP2	3.43e-06	10	71	3	CID000008763
Drug	sodium cholate	NPC1 UGT1A4 DHDH PNLIP PNLIPRP1 PNLIPRP2 UGT1A5 NR1H3 LAP3	4.87e-06	408	71	9	CID000000303
Drug	pentanal	PNLIP PNLIPRP1 PNLIPRP2 TNFRSF8 IL6	1.25e-05	96	71	5	CID000008063
Drug	monogalactosyldiacylglycerol	PNLIP PNLIPRP1 PNLIPRP2 POLB	1.65e-05	49	71	4	CID005327038
Drug	8-prenylnaringenin	UGT1A4 GSDME UGT1A5 IL6	2.10e-05	52	71	4	CID000480764
Drug	propanidid	PLB1 PNLIP PNLIPRP1 PNLIPRP2	2.26e-05	53	71	4	CID000015004
Drug	Mordant Yellow 1	POLB CPB1 IL6	2.29e-05	18	71	3	CID005354366
Drug	Gp3G	PNLIP PNLIPRP1 PNLIPRP2 PLCL1	2.82e-05	56	71	4	CID000444841
Drug	pheophytin	UGT1A4 DUOX1 UGT1A5 DUOX2 NR1H3 LAP3 IL6	2.93e-05	284	71	7	CID000000250
Drug	Lincomycin hydrochloride [859-18-7]; Down 200; 9uM; MCF7; HT_HG-U133A	TRAF3 METTL5 GLRX3 NEUROD4 MYL10 ITPKB	3.59e-05	198	71	6	5992_DN
Drug	Rifampicin [13292-46-1]; Up 200; 4.8uM; HL60; HT_HG-U133A	DLC1 NEUROD4 TNFRSF8 PAPPA CPB1 POFUT1	3.59e-05	198	71	6	2487_UP
Drug	Yohimbinic acid monohydrate [27801-27-2]; Up 200; 11.2uM; HL60; HT_HG-U133A	ITCH CPB1 POFUT1 PLCL1 MYL10 SVEP1	3.80e-05	200	71	6	2147_UP
Disease	phenylketonuria (implicated_via_orthology)	DUOX1 DUOX2	3.32e-05	4	70	2	DOID:9281 (implicated_via_orthology)
Disease	Colorectal Carcinoma	ZDHHC2 ELOA2 DLC1 ACACA TCOF1 PPM1E ETFDH ADAMTS18 DSCAML1	4.13e-05	702	70	9	C0009402
Disease	Autosomal dominant nonsyndromic hearing loss	MYH9 GSDME MYH14	4.47e-05	29	70	3	cv:C5779548
Disease	response to dolutegravir	UGT1A4 TRAF3 UGT1A5	4.96e-05	30	70	3	EFO_0600017
Disease	sensorineural hearing loss (is_implicated_in)	MYH9 GSDME MYH14	6.63e-05	33	70	3	DOID:10003 (is_implicated_in)
Disease	age of onset of childhood onset asthma	TRAF3 CNNM2 NFIC IL6	6.93e-05	92	70	4	OBA_2001015
Disease	X-11793--oxidized bilirubin measurement	UGT1A4 UGT1A5	1.54e-04	8	70	2	EFO_0021260
Disease	Succinimide measurement	UGT1A4 UGT1A5	1.54e-04	8	70	2	EFO_0022118
Disease	X-11530 measurement	UGT1A4 UGT1A5	1.54e-04	8	70	2	EFO_0021249
Disease	sulfate of piperine metabolite C16H19NO3 (2) measurement	UGT1A4 UGT1A5	1.54e-04	8	70	2	EFO_0801034
Disease	cholelithiasis, bilirubin measurement	UGT1A4 UGT1A5	1.54e-04	8	70	2	EFO_0004570, EFO_0004799
Disease	X-11522 measurement	UGT1A4 UGT1A5	1.54e-04	8	70	2	EFO_0800696
Disease	X-10458 measurement	UGT1A4 UGT1A5	1.54e-04	8	70	2	EFO_0800692
Disease	X-24849 measurement	UGT1A4 UGT1A5	1.54e-04	8	70	2	EFO_0800909
Disease	membrane-associated progesterone receptor component 1 measurement	UGT1A4 UGT1A5	1.54e-04	8	70	2	EFO_0802740
Disease	X-16946 measurement	UGT1A4 UGT1A5	1.54e-04	8	70	2	EFO_0800766
Disease	X-11442 measurement	UGT1A4 UGT1A5	1.98e-04	9	70	2	EFO_0021236
Disease	X-11441 measurement	UGT1A4 UGT1A5	1.98e-04	9	70	2	EFO_0021235
Disease	circulating cell free DNA measurement	UGT1A4 UGT1A5	1.98e-04	9	70	2	EFO_0004739
Disease	sulfate of piperine metabolite C18H21NO3 (3) measurement	UGT1A4 UGT1A5	1.98e-04	9	70	2	EFO_0801037
Disease	testis-specific chromodomain protein Y 1 measurement	UGT1A4 UGT1A5	1.98e-04	9	70	2	EFO_0802127
Disease	sulfate of piperine metabolite C18H21NO3 (1) measurement	UGT1A4 UGT1A5	1.98e-04	9	70	2	EFO_0801036
Disease	X-11880 measurement	UGT1A4 UGT1A5	1.98e-04	9	70	2	EFO_0800698
Disease	bilirubin measurement, response to xenobiotic stimulus	UGT1A4 UGT1A5	1.98e-04	9	70	2	EFO_0004570, GO_0009410
Disease	primary bacterial infectious disease (implicated_via_orthology)	DUOX1 DUOX2	1.98e-04	9	70	2	DOID:0050338 (implicated_via_orthology)
Disease	protein-tyrosine kinase 6 measurement	UGT1A4 UGT1A5	1.98e-04	9	70	2	EFO_0020691
Disease	X-21448 measurement	UGT1A4 UGT1A5	2.47e-04	10	70	2	EFO_0800816
Disease	UDP-glucuronosyltransferase 1-6 measurement	UGT1A4 UGT1A5	2.47e-04	10	70	2	EFO_0802185
Disease	X-23974 measurement	UGT1A4 UGT1A5	2.47e-04	10	70	2	EFO_0800867
Disease	bilirubin measurement, response to tenofovir	UGT1A4 UGT1A5	2.47e-04	10	70	2	EFO_0004570, EFO_0009279
Disease	X-21796 measurement	UGT1A4 UGT1A5	3.01e-04	11	70	2	EFO_0800825
Disease	pregnenetriol sulfate measurement	UGT1A4 UGT1A5	3.01e-04	11	70	2	EFO_0800586
Disease	plasma N-desmethylclozapine measurement	UGT1A4 UGT1A5	3.01e-04	11	70	2	EFO_0600039
Disease	insomnia, bilirubin measurement	UGT1A4 UGT1A5	3.01e-04	11	70	2	EFO_0004570, EFO_0004698
Disease	histidine betaine (hercynine) measurement	UGT1A4 UGT1A5	3.01e-04	11	70	2	EFO_0800972
Disease	aldosterone measurement	UGT1A4 UGT1A5	3.01e-04	11	70	2	EFO_0010219
Disease	biliverdin measurement	UGT1A4 UGT1A5	3.61e-04	12	70	2	EFO_0021033
Disease	p-cresol glucuronide measurement	UGT1A4 UGT1A5	3.61e-04	12	70	2	EFO_0800079
Disease	retinol dehydrogenase 16 measurement	UGT1A4 UGT1A5	4.25e-04	13	70	2	EFO_0802007
Disease	hypothyroidism (implicated_via_orthology)	DUOX1 DUOX2	4.25e-04	13	70	2	DOID:1459 (implicated_via_orthology)
Disease	pregnenetriol disulfate measurement	UGT1A4 UGT1A5	4.25e-04	13	70	2	EFO_0800587
Disease	congenital hypothyroidism (implicated_via_orthology)	DUOX1 DUOX2	4.96e-04	14	70	2	DOID:0050328 (implicated_via_orthology)
Disease	Abnormal behavior	METTL5 BCORL1	6.52e-04	16	70	2	C0233514
Disease	hippocampal volume	ETFDH PAPPA PLCL1 SQOR DSCAML1	7.08e-04	297	70	5	EFO_0005035
Disease	X-21441 measurement	UGT1A4 UGT1A5	7.37e-04	17	70	2	EFO_0800814
Disease	low density lipoprotein cholesterol measurement, body fat percentage	UGT1A4 UGT1A5	7.37e-04	17	70	2	EFO_0004611, EFO_0007800
Disease	Nonsyndromic genetic hearing loss	MYH9 GSDME MYH14	7.94e-04	76	70	3	cv:C5680182
Disease	Corneal astigmatism	BMP3 ETFDH HERC2	8.25e-04	77	70	3	EFO_1002040
Disease	angiopoietin-related protein 1 measurement	UGT1A4 UGT1A5	8.28e-04	18	70	2	EFO_0801382
Disease	Hypermetropia, Myopia	BMP3 PPM1E PLCL1 DSCAML1	1.08e-03	189	70	4	HP_0000540, HP_0000545
Disease	tissue factor measurement	UGT1A4 UGT1A5	1.13e-03	21	70	2	EFO_0010623
Disease	feeling nervous measurement	CNNM2 ITCH ETFDH	1.18e-03	87	70	3	EFO_0009597
Disease	hip circumference	NPC1 MYH9 CNNM2 NRXN1 NFIC	1.26e-03	338	70	5	EFO_0005093
Disease	apolipoprotein L1 measurement	MYH9 DLC1	1.61e-03	25	70	2	EFO_0021854
Disease	spontaneous preterm birth	DLC1 NEUROD4 SVEP1	1.80e-03	101	70	3	EFO_0006917
Disease	caudate volume change measurement, age at assessment	DLC1 NRXN1	1.87e-03	27	70	2	EFO_0008007, EFO_0021491
Disease	coronary artery disease	NPC1 CNNM2 DLC1 PNLIPRP2 NRXN1 DUOX2 MAGI3 PLCL1 SVEP1	2.00e-03	1194	70	9	EFO_0001645
Disease	stimulant use measurement	DLC1 FAM135A	2.02e-03	28	70	2	EFO_0600076
Disease	xanthurenate measurement	UGT1A4 UGT1A5	2.16e-03	29	70	2	EFO_0010551
Disease	gallstones	UGT1A4 TRAF3 UGT1A5	2.18e-03	108	70	3	EFO_0004210
Disease	Malignant mesothelioma	AGO1 TNFRSF8 IL6	2.24e-03	109	70	3	C0345967
Disease	non-alcoholic fatty liver disease, type 2 diabetes mellitus	BMP3 PLB1 ADAMTS18	2.30e-03	110	70	3	EFO_0003095, MONDO_0005148

Protein segments in the cluster

Peptide	Gene	Start	Entry
GACQFPMPKSLKPSN	BMP3	401	P12645
ECFKMPQSLGALGGK	ATG4A	246	Q8WYN0
DNNSMNCPGPKLEKP	ANTXRL	306	A6NF34
CGLPEAPKNGMVFGK	CSMD2	2531	Q7Z408
CPGPEDAGSKQLFMT	GSDME	371	O60443
SKDAGMPIQGQPCFC	AGO1	476	Q9UL18
STPKMEGPQGACGLK	BCORL1	961	Q5H9F3
PGCVLAKMQLDNPSK	ACACA	811	Q13085
KDAGMPIQGQPCFCK	AGO4	471	Q9HCK5
SCAPNQVKVAGKPMY	CEMIP	461	Q8WUJ3
AMSGKVKDGTPCSPN	ADAMTS18	696	Q8TE60
MHGQCLGPNDTKPIK	RBM45	86	Q8IUH3
CLQAKDGMTPKGPNH	GLRA3	391	O75311
KGPAPKMLGNELCSV	NR1H3	86	Q13133
LAPLCENMPSGKANK	LAP3	331	P28838
GPPGMTKNVEKACQL	DUOX1	1521	Q9NRD9
GNNPNGREAKMICFK	ELOA2	631	Q8IYF1
KGETCMNPQDFKPGA	MAGI3	521	Q5TCQ9
LDFFPNGGVEMPGCK	PNLIP	241	P16233
NGGVEMPGCKKNILS	PNLIP	246	P16233
KGTPQEPRCGFSKQM	GLRX3	151	O76003
GPDGTKSVFGQMCAK	HERC2	4436	O95714
NTGKQIPPKHMECAG	CCDC190	221	Q86UF4
KIGVFSCGPPGMTKN	DUOX2	1511	Q9NRD8
KPNLDTMCKGFQSPD	FAM135A	941	Q9P2D6
NAIPKGFMDGKQACE	MYH14	751	Q7Z406
PNGGESMPGCKKNAL	PNLIPRP1	246	P54315
FPPNDPKAGTQGKCM	LPO	261	P22079
PKAGTQGKCMPFFRA	LPO	266	P22079
GQPSMCQAFAADPKP	FGFBP2	76	Q9BYJ0
MLSVQPDTKPKGCAG	LMO3	1	Q8TAP4
PNSIPKGFMDGKQAC	MYH9	726	P35579
KQMFAAFPPDVCGNL	MYL10	196	Q9BUA6
PGSPVSNNFMGCLKE	NRXN1	426	Q9ULB1
KKVTPFPMSCDLQGD	PAPPA	1591	Q13219
SKKGEMLNTFCGSPP	NIM1K	221	Q8IY84
MFGPGAPKKANLINE	PPM1E	591	Q8WY54
MFLSDNPNPKCGKGG	NPC1	1001	O15118
NPPFGTKNNKGTDMA	METTL5	126	Q9NRN9
MGSNGPQKFCIEKVG	ITCH	846	Q96J02
GCSPGFMNVPKIKGT	ETFDH	386	Q16134
GMNVCQPTPGKALKE	CKAP5	1356	Q14008
PGEQFSLMCAAKGAP	DSCAML1	421	Q8TD84
PPVPKDCNFDNGAGM	DHDH	271	Q9UQ10
MCGKKNSPVEGAPLS	SLC44A3	71	Q8N4M1
GETKFMGVCQLPSKN	POLB	231	P06746
KAGQNKPAIFMDCGF	CPB1	161	P15086
NLPKMAEKDGCFQSG	IL6	91	P05231
EFNKPANPGADGKKM	PRIMPOL	116	Q96LW4
FPNGGKEMPGCKKNV	PNLIPRP2	246	P54317
DKKTCPMKEGNPFGP	POFUT1	136	Q9H488
MNAAGCLKPKFPFLS	AK9	1816	Q5TCS8
NTPVKCAGAPQKIMY	SQOR	196	Q9Y6N5
CQTMKVGTKGPGDNL	TEX47	186	Q8TBZ9
PDGKQEAKPQQAAGM	TCOF1	1241	Q13428
GGPSLCSSQVKKGMP	ITPKB	221	P27987
AGQVKQGTPMCVPSK	EIF5B	1116	O60841
FPCNPNKLGVNMPSK	PLB1	46	Q6P1J6
VPGMHFQCAPKLNGD	SGMS2	181	Q8NHU3
PTLAMPANGGFKCVD	SRPX	121	P78539
APGCVLSNPDQKGKM	NFIC	101	P08651
EAISCKKPNPVMNGS	SVEP1	2771	Q4LDE5
SPPKVKAEDGMQCLQ	DLC1	306	Q96QB1
MPCGKQGNLQVPGSK	APOL5	1	Q9BWW9
ACEPKVKMAGGQAAA	CNNM2	6	Q9H8M5
QNFPKPKGACAKGDV	PLCL1	731	Q15111
FKKPTGEMNIASGCP	TRAF3	521	Q13114
NPSKCGCPFALKMAA	UNC80	1331	Q8N2C7
PNMVFIGGINCANGK	UGT1A5	271	P35504
CPAGMIVKFPGTAQK	TNFRSF8	131	P28908
PAKPANMGQDPDCFG	nan	281	Q3C1V9
SINPGKCKAGMSNPA	ZDHHC2	346	Q9UIJ5
PNMVFIGGINCANGK	UGT1A4	271	P22310
GKGFVEMLCKGLSQP	NEUROD4	151	Q9HD90