Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

VLDLR LRP1B LDLR LRP8 STAB1 LRP1 LRP2

1.22e-12161087GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

VLDLR LRP1B LDLR LRP8 STAB1 LRP1 LRP2

1.21e-11211087GO:0030228
GeneOntologyMolecularFunctioncalcium ion binding

VLDLR FAT4 PKD1L3 LRP1B LDLR F10 SVEP1 CRB1 LRP8 STAB1 JAG2 RGN FBN2 LRP1 LRP2 LTBP1 FBN3 NOTCH2

1.04e-0774910818GO:0005509
GeneOntologyMolecularFunctioncargo receptor activity

VLDLR LRP1B LDLR LRP8 STAB1 LRP1 LRP2

3.88e-07851087GO:0038024
GeneOntologyMolecularFunctionvery-low-density lipoprotein particle receptor activity

VLDLR LDLR LRP8

6.13e-0741083GO:0030229
GeneOntologyMolecularFunctionextracellular matrix structural constituent

VWF LAMB1 LAMB2 SSPOP FBN2 COL14A1 LTBP1 FBN3

8.39e-061881088GO:0005201
GeneOntologyMolecularFunctionreelin receptor activity

VLDLR LRP8

2.90e-0521082GO:0038025
GeneOntologyMolecularFunctionlipoprotein particle binding

VLDLR LDLR LRP8 STAB1

3.72e-05351084GO:0071813
GeneOntologyMolecularFunctionprotein-lipid complex binding

VLDLR LDLR LRP8 STAB1

3.72e-05351084GO:0071814
GeneOntologyMolecularFunctionstructural constituent of synapse-associated extracellular matrix

LAMB1 LAMB2

8.66e-0531082GO:0150043
GeneOntologyMolecularFunctionprocollagen-proline 3-dioxygenase activity

P3H3 P3H2

8.66e-0531082GO:0019797
GeneOntologyMolecularFunctionapolipoprotein binding

VLDLR LRP8 LRP1

1.64e-04201083GO:0034185
GeneOntologyMolecularFunctionpeptidyl-proline 3-dioxygenase activity

P3H3 P3H2

1.73e-0441082GO:0031544
GeneOntologyMolecularFunctionclathrin binding

LDLR AP1B1 AP2B1 LRP1

3.77e-04631084GO:0030276
GeneOntologyMolecularFunctionprocollagen-proline dioxygenase activity

P3H3 P3H2

7.94e-0481082GO:0019798
GeneOntologyMolecularFunctionubiquitin-like ligase-substrate adaptor activity

PRAMEF7 PRAMEF12 FBXL19 PRAMEF8

1.02e-03821084GO:1990756
GeneOntologyMolecularFunctionenzyme-substrate adaptor activity

PRAMEF7 PRAMEF12 FBXL19 PRAMEF8

1.77e-03951084GO:0140767
GeneOntologyMolecularFunctionpeptidyl-proline dioxygenase activity

P3H3 P3H2

1.85e-03121082GO:0031543
GeneOntologyMolecularFunctionclathrin heavy chain binding

LDLR LRP1

1.85e-03121082GO:0032050
GeneOntologyMolecularFunctiondioxygenase activity

KDM5B ASPHD1 P3H3 P3H2

1.98e-03981084GO:0051213
GeneOntologyMolecularFunctiontransforming growth factor beta receptor activity

AMHR2 LTBP1

2.17e-03131082GO:0005024
GeneOntologyMolecularFunctionamyloid-beta binding

LDLR FBXO2 LRP8 LRP1

2.29e-031021084GO:0001540
GeneOntologyMolecularFunctionmolecular adaptor activity

PRAMEF7 AMFR KDM5B FSCN3 TRIM21 PRAMEF12 BTAF1 FBXL19 PRAMEF8 LDLR AP2B1 TRIM28 COL14A1 AKAP13 LTBP1 NUP153

2.53e-03135610816GO:0060090
GeneOntologyMolecularFunctionintegrin binding

VWF LAMB1 LAMB2 SVEP1 CCN3

2.63e-031751085GO:0005178
GeneOntologyMolecularFunctionprotease binding

AMFR VWF LDLR LRP1 RNF139

3.04e-031811085GO:0002020
GeneOntologyBiologicalProcesspositive regulation of lysosomal protein catabolic process

LDLR LRP1 LRP2

1.24e-0651043GO:1905167
GeneOntologyBiologicalProcesspositive regulation of protein catabolic process in the vacuole

LDLR LRP1 LRP2

4.30e-0671043GO:1904352
GeneOntologyBiologicalProcessregulation of lysosomal protein catabolic process

LDLR LRP1 LRP2

2.65e-05121043GO:1905165
GeneOntologyBiologicalProcessregulation of protein catabolic process in the vacuole

LDLR LRP1 LRP2

4.35e-05141043GO:1904350
GeneOntologyBiologicalProcessregulation of presynapse assembly

SLITRK4 SLITRK3 SLITRK1 SLITRK6

5.89e-05421044GO:1905606
GeneOntologyBiologicalProcesscoronary vasculature development

ABCC9 AP2B1 LRP1 LRP2 LTBP1

6.29e-05831045GO:0060976
GeneOntologyBiologicalProcessregulation of presynapse organization

SLITRK4 SLITRK3 SLITRK1 SLITRK6

8.46e-05461044GO:0099174
GeneOntologyBiologicalProcessoocyte development

PRAMEF7 PRAMEF12 PRAMEF8 ZGLP1 ATM

1.45e-04991045GO:0048599
GeneOntologyBiologicalProcesssequestering of TGFbeta in extracellular matrix

FBN2 LTBP1

1.50e-0441042GO:0035583
GeneOntologyBiologicalProcessoocyte differentiation

PRAMEF7 PRAMEF12 PRAMEF8 ZGLP1 ATM

1.75e-041031045GO:0009994
GeneOntologyBiologicalProcesslysosomal protein catabolic process

LDLR LRP1 LRP2

2.33e-04241043GO:1905146
GeneOntologyBiologicalProcesspresynapse assembly

SLITRK4 SLITRK3 SLITRK1 SLITRK6

2.39e-04601044GO:0099054
GeneOntologyBiologicalProcesschemoattraction of axon

LRP1 LRP2

2.49e-0451042GO:0061642
GeneOntologyBiologicalProcessaxon extension involved in regeneration

LAMB2 LRP1

2.49e-0451042GO:0048677
GeneOntologyCellularComponentubiquitin ligase complex

PRAMEF7 AMFR TRIM21 PRAMEF12 FBXL19 PRAMEF8 FBXO2 FBXL4 ANKIB1 FBXL20

1.45e-0535210810GO:0000151
GeneOntologyCellularComponentcullin-RING ubiquitin ligase complex

PRAMEF7 TRIM21 PRAMEF12 FBXL19 PRAMEF8 FBXO2 FBXL4 FBXL20

1.45e-052121088GO:0031461
GeneOntologyCellularComponentSCF ubiquitin ligase complex

TRIM21 FBXL19 FBXO2 FBXL4 FBXL20

3.11e-05701085GO:0019005
GeneOntologyCellularComponentmicrofibril

FBN2 LTBP1 FBN3

3.69e-05131083GO:0001527
GeneOntologyCellularComponentclathrin-coated pit

VLDLR LDLR AP2B1 LRP1 LRP2

5.92e-05801085GO:0005905
GeneOntologyCellularComponentextracellular matrix

VWF ZAN LAMB1 LAMB2 SSPOP SVEP1 FBN2 P3H2 COL14A1 LTBP1 FBN3 CCN3

1.47e-0465610812GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

VWF ZAN LAMB1 LAMB2 SSPOP SVEP1 FBN2 P3H2 COL14A1 LTBP1 FBN3 CCN3

1.52e-0465810812GO:0030312
GeneOntologyCellularComponentcell surface

VLDLR VWF SLITRK3 CD83 PKD1L3 LDLR F10 ADAM28 LRP8 ANTXR2 KCNC1 P2RX2 LRP1 LRP2 SLITRK6 NOTCH2

1.84e-04111110816GO:0009986
GeneOntologyCellularComponentreceptor complex

VLDLR AMHR2 PKD1L3 LRP1B LDLR LRP8 P2RX2 LRP1 LRP2 LTK NOTCH2

2.10e-0458110811GO:0043235
GeneOntologyCellularComponentlysosomal membrane

VLDLR LDLR AP1B1 AP2B1 HPS4 LRP1 LRP2 ZFYVE26 TMEM63A

6.59e-044621089GO:0005765
GeneOntologyCellularComponentlytic vacuole membrane

VLDLR LDLR AP1B1 AP2B1 HPS4 LRP1 LRP2 ZFYVE26 TMEM63A

6.59e-044621089GO:0098852
GeneOntologyCellularComponentDerlin-1 retrotranslocation complex

AMFR RNF139

7.26e-0481082GO:0036513
GeneOntologyCellularComponentlaminin complex

LAMB1 LAMB2

1.16e-03101082GO:0043256
GeneOntologyCellularComponentvacuolar membrane

VLDLR LDLR AP1B1 AP2B1 HPS4 LRP1 LRP2 ZFYVE26 TMEM63A

1.27e-035071089GO:0005774
GeneOntologyCellularComponentclathrin-coated vesicle

VWF LDLR AP1B1 AP2B1 LRP1 LRP2

1.46e-032371086GO:0030136
GeneOntologyCellularComponentendoplasmic reticulum lumen

LAMB1 LAMB2 F10 P3H2 COL14A1 LTBP1 POGLUT2

1.70e-033321087GO:0005788
GeneOntologyCellularComponentcollagen-containing extracellular matrix

VWF LAMB1 LAMB2 SSPOP FBN2 P3H2 COL14A1 LTBP1 CCN3

1.72e-035301089GO:0062023
GeneOntologyCellularComponentCul2-RING ubiquitin ligase complex

PRAMEF7 PRAMEF12 PRAMEF8

1.84e-03471083GO:0031462
GeneOntologyCellularComponentvacuole

VLDLR MAN2B1 TRIM21 LDLR AP1B1 AP2B1 HPS4 LRP1 LRP2 ZFYVE26 C4BPA TMEM63A

2.66e-0391310812GO:0005773
MousePhenoabnormal cochlear labyrinth morphology

FAT4 MAN2B1 FBXO2 JAG2 LOXHD1 P2RX2 VANGL1 LRP2 SLITRK6 PPIP5K2

4.74e-062359610MP:0004426
MousePhenoabnormal scala media morphology

FAT4 MAN2B1 FBXO2 JAG2 LOXHD1 P2RX2 VANGL1 LRP2 SLITRK6 PPIP5K2

4.74e-062359610MP:0003169
MousePhenoabnormal cochlea morphology

FAT4 MAN2B1 FBXO2 JAG2 LOXHD1 P2RX2 VANGL1 LRP2 SLITRK6 PPIP5K2

7.63e-062489610MP:0000031
MousePhenohearing/vestibular/ear phenotype

PRAMEF7 FAT4 MAN2B1 PRAMEF12 PRAMEF8 LDLR FBXO2 JAG2 RGN LOXHD1 FBN2 P2RX2 VANGL1 HPS4 DENND6B LRP2 ZFYVE26 SLITRK6 PPIP5K2

1.03e-059059619MP:0005377
MousePhenoabnormal membranous labyrinth morphology

FAT4 MAN2B1 FBXO2 JAG2 LOXHD1 P2RX2 VANGL1 LRP2 SLITRK6 PPIP5K2

1.23e-052629610MP:0000035
MousePhenoabnormal inner ear morphology

FAT4 MAN2B1 FBXO2 JAG2 LOXHD1 P2RX2 VANGL1 LRP2 SLITRK6 PPIP5K2

4.29e-053039610MP:0000026
MousePhenoabnormal cochlear hair cell morphology

FAT4 FBXO2 JAG2 LOXHD1 P2RX2 VANGL1 SLITRK6 PPIP5K2

7.39e-05202968MP:0002622
MousePhenoabnormal somatic sensory system morphology

VLDLR FAT4 MAN2B1 LAMB2 LDLR FBXO2 CRB1 JAG2 RGN LOXHD1 P2RX2 VANGL1 RP1L1 SLITRK6 PPIP5K2

8.26e-057029615MP:0000959
MousePhenoabnormal ear morphology

FAT4 MAN2B1 FBXO2 JAG2 LOXHD1 FBN2 P2RX2 VANGL1 HPS4 LRP2 SLITRK6 PPIP5K2

8.73e-054709612MP:0002102
MousePhenoabnormal cochlear sensory epithelium morphology

FAT4 FBXO2 JAG2 LOXHD1 P2RX2 VANGL1 SLITRK6 PPIP5K2

8.77e-05207968MP:0003308
MousePhenoabnormal organ of Corti morphology

FAT4 FBXO2 JAG2 LOXHD1 P2RX2 VANGL1 SLITRK6 PPIP5K2

9.38e-05209968MP:0000042
MousePhenoabnormal tail morphology

PRAMEF7 FAT4 ASPHD1 LAMB1 PRAMEF12 PRAMEF8 SVEP1 JAG2 FBN2 LRP2 CCN3

9.75e-054039611MP:0002111
MousePhenoabnormal hair cell morphology

FAT4 FBXO2 JAG2 LOXHD1 P2RX2 VANGL1 SLITRK6 PPIP5K2

1.11e-04214968MP:0000045
MousePhenoabnormal ST segment

FSD2 ABCC9 ZNF395 FBN2

1.29e-0438964MP:0003897
MousePhenodelayed head development

BTAF1 FBXL19

1.39e-043962MP:0012177
MousePhenoabnormal mechanoreceptor morphology

FAT4 FBXO2 JAG2 LOXHD1 P2RX2 VANGL1 SLITRK6 PPIP5K2

1.87e-04231968MP:0000972
MousePhenoabnormal spermatogonia proliferation

PRAMEF7 PRAMEF12 PRAMEF8 ZGLP1

2.97e-0447964MP:0002685
MousePhenoabnormal cochlear ganglion morphology

MAN2B1 FBXO2 RGN LOXHD1 SLITRK6

3.44e-0488965MP:0002855
MousePhenoabnormal hearing physiology

PRAMEF7 PRAMEF12 PRAMEF8 LDLR FBXO2 RGN LOXHD1 P2RX2 DENND6B LRP2 ZFYVE26 SLITRK6 PPIP5K2

4.38e-046439613MP:0001963
DomainGrowth_fac_rcpt_

VLDLR FAT4 LAMB1 LAMB2 FBXL19 LRP1B LDLR SVEP1 CRB1 LRP8 STAB1 JAG2 FBN2 LRP1 LRP2 LTBP1 FBN3 NOTCH2 CCN3

2.56e-2015610619IPR009030
DomainEGF_1

VLDLR FAT4 ZAN LAMB1 LAMB2 SSPOP LRP1B LDLR F10 ADAM28 SVEP1 CRB1 LRP8 STAB1 JAG2 FBN2 LRP1 LRP2 LTBP1 FBN3 NOTCH2

8.57e-1925510621PS00022
DomainEGF_2

VLDLR FAT4 ZAN LAMB1 LAMB2 SSPOP LRP1B LDLR F10 ADAM28 SVEP1 CRB1 LRP8 STAB1 JAG2 FBN2 LRP1 LRP2 LTBP1 FBN3 NOTCH2

1.90e-1826510621PS01186
DomainEGF

VLDLR FAT4 ZAN LAMB1 LAMB2 LRP1B LDLR F10 ADAM28 SVEP1 CRB1 LRP8 STAB1 JAG2 FBN2 LRP1 LRP2 LTBP1 FBN3 NOTCH2

3.27e-1823510620SM00181
DomainEGF_Ca-bd_CS

VLDLR FAT4 LRP1B LDLR F10 SVEP1 CRB1 LRP8 JAG2 FBN2 LRP1 LRP2 LTBP1 FBN3 NOTCH2

7.72e-189710615IPR018097
DomainEGF_CA

VLDLR FAT4 LRP1B LDLR F10 SVEP1 CRB1 LRP8 STAB1 JAG2 FBN2 LRP1 LRP2 LTBP1 FBN3 NOTCH2

9.00e-1812210616SM00179
DomainEGF-like_dom

VLDLR FAT4 ZAN LAMB1 LAMB2 LRP1B LDLR F10 ADAM28 SVEP1 CRB1 LRP8 STAB1 JAG2 FBN2 LRP1 LRP2 LTBP1 FBN3 NOTCH2

1.03e-1724910620IPR000742
DomainEGF_CA

VLDLR FAT4 LRP1B LDLR F10 SVEP1 CRB1 LRP8 JAG2 FBN2 LRP1 LRP2 LTBP1 FBN3 NOTCH2

1.06e-179910615PS01187
DomainEGF-like_Ca-bd_dom

VLDLR FAT4 LRP1B LDLR F10 SVEP1 CRB1 LRP8 STAB1 JAG2 FBN2 LRP1 LRP2 LTBP1 FBN3 NOTCH2

1.18e-1712410616IPR001881
DomainASX_HYDROXYL

VLDLR FAT4 LRP1B LDLR F10 SVEP1 CRB1 LRP8 JAG2 FBN2 LRP1 LRP2 LTBP1 FBN3 NOTCH2

1.25e-1710010615PS00010
DomainEGF-like_CS

VLDLR FAT4 ZAN LAMB1 LAMB2 LRP1B LDLR F10 ADAM28 SVEP1 CRB1 LRP8 STAB1 JAG2 FBN2 LRP1 LRP2 LTBP1 FBN3 NOTCH2

2.59e-1726110620IPR013032
DomainEGF-type_Asp/Asn_hydroxyl_site

VLDLR FAT4 LRP1B LDLR F10 SVEP1 CRB1 LRP8 JAG2 FBN2 LRP1 LRP2 LTBP1 FBN3 NOTCH2

3.10e-1710610615IPR000152
DomainEGF_3

VLDLR FAT4 ZAN SSPOP LRP1B LDLR F10 ADAM28 SVEP1 CRB1 LRP8 STAB1 JAG2 FBN2 LRP1 LRP2 LTBP1 FBN3 NOTCH2

6.41e-1723510619PS50026
DomainEGF_CA

VLDLR FAT4 LRP1B LDLR SVEP1 LRP8 JAG2 FBN2 LRP1 LRP2 LTBP1 FBN3 NOTCH2

1.83e-158610613PF07645
DomainEGF

VLDLR ZAN LRP1B F10 SVEP1 CRB1 LRP8 STAB1 JAG2 LRP1 LRP2 LTBP1 FBN3 NOTCH2

1.21e-1412610614PF00008
DomainLdl_recept_b

VLDLR LRP1B LDLR LRP8 LRP1 LRP2

8.38e-11141066PF00058
DomainLDLRB

VLDLR LRP1B LDLR LRP8 LRP1 LRP2

8.38e-11141066PS51120
DomainLY

VLDLR LRP1B LDLR LRP8 LRP1 LRP2

1.39e-10151066SM00135
DomainLDLR_classB_rpt

VLDLR LRP1B LDLR LRP8 LRP1 LRP2

1.39e-10151066IPR000033
DomainhEGF

FAT4 SVEP1 CRB1 JAG2 FBN2 FBN3 NOTCH2

1.67e-10281067PF12661
Domain-

VLDLR LRP1B LDLR LRP8 RGN LRP1 LRP2

2.06e-093910672.120.10.30
DomainLDLR_class-A_CS

VLDLR SSPOP LRP1B LDLR LRP8 LRP1 LRP2

2.48e-09401067IPR023415
DomainLdl_recept_a

VLDLR SSPOP LRP1B LDLR LRP8 LRP1 LRP2

5.90e-09451067PF00057
DomaincEGF

LRP1B FBN2 LRP1 LRP2 LTBP1 FBN3

6.08e-09261066PF12662
DomaincEGF

LRP1B FBN2 LRP1 LRP2 LTBP1 FBN3

6.08e-09261066IPR026823
Domain6-blade_b-propeller_TolB-like

VLDLR LRP1B LDLR LRP8 RGN LRP1 LRP2

6.93e-09461067IPR011042
Domain-

VLDLR SSPOP LRP1B LDLR LRP8 LRP1 LRP2

6.93e-094610674.10.400.10
DomainLDLRA_1

VLDLR SSPOP LRP1B LDLR LRP8 LRP1 LRP2

9.44e-09481067PS01209
DomainLDrepeatLR_classA_rpt

VLDLR SSPOP LRP1B LDLR LRP8 LRP1 LRP2

1.10e-08491067IPR002172
DomainLDLa

VLDLR SSPOP LRP1B LDLR LRP8 LRP1 LRP2

1.10e-08491067SM00192
DomainLDLRA_2

VLDLR SSPOP LRP1B LDLR LRP8 LRP1 LRP2

1.10e-08491067PS50068
DomainTIL_dom

VWF ZAN SSPOP LRP2

9.39e-07141064IPR002919
DomainVWFC_1

VWF ZAN SSPOP JAG2 CCN3

1.75e-06361065PS01208
DomainVWFC_2

VWF ZAN SSPOP JAG2 CCN3

2.32e-06381065PS50184
DomainVWC

VWF ZAN SSPOP JAG2 CCN3

2.32e-06381065SM00214
DomainVWC_out

VWF ZAN SSPOP JAG2

3.56e-06191064SM00215
DomainVWF_dom

VWF ZAN SSPOP JAG2 CCN3

3.85e-06421065IPR001007
DomainTB

FBN2 LTBP1 FBN3

6.12e-0671063PF00683
Domain-

FBN2 LTBP1 FBN3

9.75e-06810633.90.290.10
Domain-

PRAMEF7 SLITRK4 SLITRK3 PRAMEF12 FBXL19 PRAMEF8 SLITRK1 FBXL4 SLITRK6 FBXL20

1.45e-05321106103.80.10.10
DomainTB_dom

FBN2 LTBP1 FBN3

1.46e-0591063IPR017878
DomainTB

FBN2 LTBP1 FBN3

1.46e-0591063PS51364
DomainL_dom-like

PRAMEF7 SLITRK4 SLITRK3 PRAMEF12 FBXL19 PRAMEF8 SLITRK1 FBXL4 SLITRK6 FBXL20

1.75e-0532810610IPR032675
DomainEGF_extracell

LRP1B SVEP1 STAB1 JAG2 LRP2

2.28e-05601065IPR013111
DomainEGF_2

LRP1B SVEP1 STAB1 JAG2 LRP2

2.28e-05601065PF07974
DomainClathrin_b-adaptin_app_Ig-like

AP1B1 AP2B1

3.19e-0521062IPR013037
DomainDUF5050

LRP1B LRP1

3.19e-0521062IPR032485
Domain-

AP1B1 AP2B1

3.19e-05210622.60.40.1150
DomainDUF5050

LRP1B LRP1

3.19e-0521062PF16472
DomainConA-like_dom

FAT4 ZAN RNF135 FSD2 TRIM21 SVEP1 CRB1 COL14A1

3.54e-052191068IPR013320
DomainC8

VWF ZAN SSPOP

3.77e-05121063PF08742
DomainTIL

VWF ZAN SSPOP

3.77e-05121063PF01826
DomainUnchr_dom_Cys-rich

VWF ZAN SSPOP

4.88e-05131063IPR014853
DomainC8

VWF ZAN SSPOP

4.88e-05131063SM00832
DomainVWF_type-D

VWF ZAN SSPOP

9.43e-05161063IPR001846
DomainVWFD

VWF ZAN SSPOP

9.43e-05161063PS51233
DomainVWD

VWF ZAN SSPOP

9.43e-05161063SM00216
DomainVWD

VWF ZAN SSPOP

9.43e-05161063PF00094
DomainAP_complex_bsu_1_2_4

AP1B1 AP2B1

9.54e-0531062IPR016342
DomainLaminin_IV_B

LAMB1 LAMB2

9.54e-0531062IPR013015
DomainLAMININ_IVB

LAMB1 LAMB2

9.54e-0531062PS51116
DomainB2-adapt-app_C

AP1B1 AP2B1

9.54e-0531062PF09066
DomainFBN

FBN2 FBN3

9.54e-0531062IPR011398
DomainCTCK_1

VWF SSPOP CCN3

1.36e-04181063PS01185
DomainLeu-rich_rpt_Cys-con_subtyp

FBXL19 FBXL4 FBXL20

1.61e-04191063IPR006553
DomainLRR_CC

FBXL19 FBXL4 FBXL20

1.61e-04191063SM00367
DomainPRAME_family

PRAMEF7 PRAMEF12 PRAMEF8

1.61e-04191063IPR026271
DomainB2-adapt-app_C

AP1B1 AP2B1

1.90e-0441062SM01020
DomainB-adaptin_app_sub_C

AP1B1 AP2B1

1.90e-0441062IPR015151
DomainZnf_FYVE_PHD

KDM5B FBXL19 TRIM28 ANKIB1 ZFYVE19 ZFYVE26

1.92e-041471066IPR011011
Domain-

AMFR KDM5B RNF135 TRIM21 FBXL19 TRIM28 ANKIB1 ZFYVE19 ZFYVE26 RNF139

2.37e-04449106103.30.40.10
DomainLRR_1

SLITRK4 SLITRK3 FBXL19 SLITRK1 FBXL4 SLITRK6 FBXL20

2.53e-042191067PF00560
DomainZnf_RING/FYVE/PHD

AMFR KDM5B RNF135 TRIM21 FBXL19 TRIM28 ANKIB1 ZFYVE19 ZFYVE26 RNF139

2.83e-0445910610IPR013083
DomainVWA

VWF SVEP1 ANTXR2 COL14A1

2.87e-04561064PF00092
DomainAP_beta

AP1B1 AP2B1

3.16e-0451062IPR026739
DomainCys_knot_C

VWF SSPOP CCN3

3.73e-04251063IPR006207
DomainCTCK_2

VWF SSPOP CCN3

3.73e-04251063PS01225
DomainBeta2_adaptin/TBP_C_dom

AP1B1 AP2B1

4.72e-0461062IPR012295
Domain-

AP1B1 AP2B1

4.72e-04610623.30.310.10
DomainF-box

FBXL19 FBXO2 FBXL4 FBXL20

5.71e-04671064PF00646
DomainEGF_LAM_2

LAMB1 LAMB2 STAB1

6.45e-04301063PS50027
DomainEGF_LAM_1

LAMB1 LAMB2 STAB1

6.45e-04301063PS01248
DomainFBOX

FBXL19 FBXO2 FBXL4 FBXL20

7.50e-04721064PS50181
Domain-

VWF SVEP1 ANTXR2 COL14A1

8.31e-047410643.40.50.410
DomainCoatomer/calthrin_app_sub_C

AP1B1 AP2B1

8.74e-0481062IPR009028
DomainF-box_dom

FBXL19 FBXO2 FBXL4 FBXL20

8.74e-04751064IPR001810
DomainLeu-rich_rpt

SLITRK4 SLITRK3 FBXL19 SLITRK1 FBXL4 SLITRK6 FBXL20

9.00e-042711067IPR001611
DomainEGF_Lam

LAMB1 LAMB2 STAB1

1.02e-03351063SM00180
DomainLaminin_EGF

LAMB1 LAMB2 STAB1

1.02e-03351063PF00053
DomainAlpha_adaptinC2

AP1B1 AP2B1

1.12e-0391062PF02883
DomainClathrin_a/b/g-adaptin_app_Ig

AP1B1 AP2B1

1.12e-0391062IPR008152
DomainAlpha_adaptinC2

AP1B1 AP2B1

1.12e-0391062SM00809
DomainVWFA

VWF SVEP1 ANTXR2 COL14A1

1.22e-03821064PS50234
DomainLaminin_EGF

LAMB1 LAMB2 STAB1

1.30e-03381063IPR002049
DomainVWA

VWF SVEP1 ANTXR2 COL14A1

1.33e-03841064SM00327
DomainGFP-like

SVEP1 STAB1

1.70e-03111062IPR023413
Domain-

SVEP1 STAB1

1.70e-031110622.40.155.10
Domain2OG-FeII_Oxy_3

P3H3 P3H2

1.70e-03111062PF13640
DomainCys-rich_flank_reg_C

SLITRK4 SLITRK3 SLITRK1 SLITRK6

1.72e-03901064IPR000483
DomainLRRCT

SLITRK4 SLITRK3 SLITRK1 SLITRK6

1.72e-03901064SM00082
PathwayREACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES

SLITRK4 SLITRK3 SLITRK1 SLITRK6

6.08e-0620874M27290
PathwayREACTOME_RECEPTOR_TYPE_TYROSINE_PROTEIN_PHOSPHATASES

SLITRK4 SLITRK3 SLITRK1 SLITRK6

6.08e-0620874MM14991
PathwayWP_FAMILIAL_HYPERLIPIDEMIA_TYPE_3

VLDLR LDLR LRP1

6.21e-0513873M42551
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

VWF P3H3 LAMB1 LAMB2 FBN2 P3H2 COL14A1 LTBP1 FBN3

9.51e-05300879M610
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LDLR LRP8 LRP1 LRP2

2.14e-0448874M27642
Pubmed

The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

VLDLR LDLR LRP8 LRP1 LRP2

6.03e-127110512169628
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

AMFR VLDLR LRP1B LDLR LRP8 P2RX2 LRP1 LRP2 NOTCH2

3.72e-11101110923382219
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

VLDLR LRP1B LDLR LRP8 LRP1 LRP2

4.55e-1121110621337463
Pubmed

Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.

VLDLR LDLR LRP1 LRP2

4.72e-105110418685438
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

VLDLR LDLR LRP8 LRP1 LRP2

5.65e-1014110517389516
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

FAT4 MAN2B1 P3H3 SLITRK4 LAMB1 LAMB2 LRP1B NT5DC1 LDLR LRP8 JAG2 FBN2 TRIM28 P3H2 LRP1 LTBP1 ATM POGLUT2 NOTCH2 CCN3

1.14e-0912011102035696571
Pubmed

Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth.

SLITRK4 SLITRK3 SLITRK1 SLITRK6

1.41e-096110414550773
Pubmed

Differential expression of Slitrk family members in the mouse nervous system.

SLITRK4 SLITRK3 SLITRK1 SLITRK6

1.41e-096110419924824
Pubmed

Human SLITRK family genes: genomic organization and expression profiling in normal brain and brain tumor tissue.

SLITRK4 SLITRK3 SLITRK1 SLITRK6

1.41e-096110414557068
Pubmed

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.

VLDLR LDLR LRP8 LRP1 LRP2

2.39e-0918110510827173
Pubmed

Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2.

VLDLR LDLR LRP8 LRP1

6.57e-098110410380922
Pubmed

Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.

VLDLR LDLR LRP8 LRP1

1.18e-089110420005821
Pubmed

The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI.

VLDLR LDLR LRP1

3.08e-083110318367731
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

VLDLR LRP1B LRP1 LRP2

9.25e-0814110415082773
Pubmed

Reelin is a ligand for lipoprotein receptors.

VLDLR LDLR LRP8

1.23e-074110310571240
Pubmed

The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor.

VLDLR LDLR LRP1

1.23e-074110315863833
Pubmed

FERM-dependent E3 ligase recognition is a conserved mechanism for targeted degradation of lipoprotein receptors.

VLDLR LDLR LRP8

1.23e-074110322109552
Pubmed

LDL receptor cooperates with LDL receptor-related protein in regulating plasma levels of coagulation factor VIII in vivo.

VLDLR LDLR LRP1

1.23e-074110315840700
Pubmed

ATM binds to beta-adaptin in cytoplasmic vesicles.

AP1B1 AP2B1 ATM

1.23e-07411039707615
Pubmed

Cloning of a complementary deoxyribonucleic acid encoding the murine homolog of the very low density lipoprotein/apolipoprotein-E receptor: expression pattern and assignment of the gene to mouse chromosome 19.

VLDLR LDLR LRP1

3.06e-07511038013374
Pubmed

ApoER2 is endocytosed by a clathrin-mediated process involving the adaptor protein Dab2 independent of its Rafts' association.

LRP8 LRP1 LRP2

3.06e-075110316101684
Pubmed

PCSK9 binds to multiple receptors and can be functionally inhibited by an EGF-A peptide.

VLDLR LDLR LRP8

3.06e-075110318675252
Pubmed

Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency.

VLDLR LDLR LRP1

3.06e-075110330700132
Pubmed

POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of fibrillin-1.

FBN2 LTBP1 POGLUT2

3.06e-075110334411563
Pubmed

Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia.

VLDLR LDLR LRP1

3.06e-075110312746448
Pubmed

Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo.

VLDLR LDLR LRP1

3.06e-075110318992221
Pubmed

Low levels of copper disrupt brain amyloid-β homeostasis by altering its production and clearance.

VLDLR LDLR LRP1

3.06e-075110323959870
Pubmed

PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain.

VLDLR LDLR LRP8

6.11e-076110320453200
Pubmed

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein.

LDLR LRP1 LRP2

6.11e-07611039837937
Pubmed

Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex.

VLDLR LRP8 NOTCH2

6.11e-076110318957219
Pubmed

Apolipoprotein CI causes hypertriglyceridemia independent of the very-low-density lipoprotein receptor and apolipoprotein CIII in mice.

VLDLR LDLR LRP1

6.11e-076110316478678
Pubmed

Slitrk4 is required for the development of inhibitory neurons in the fear memory circuit of the lateral amygdala.

SLITRK4 SLITRK3 SLITRK1 SLITRK6

6.63e-0722110438736483
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

AP1B1 AP2B1 LRP1 LRP2 TRAPPC10 LTBP1

8.17e-07100110625807483
Pubmed

Slitrks control excitatory and inhibitory synapse formation with LAR receptor protein tyrosine phosphatases.

SLITRK4 SLITRK3 SLITRK1

1.07e-067110323345436
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

VWF LAMB1 LAMB2 LDLR SVEP1 COL14A1 LTBP1 CCN3

1.31e-06248110824006456
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

VWF LAMB1 LAMB2 SSPOP FBN2 COL14A1 LTBP1

1.49e-06175110728071719
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

VWF LAMB1 LAMB2 JAG2 LRP1 LTBP1

2.16e-06118110621078624
Pubmed

Targeted inactivation of the mouse alpha 2-macroglobulin gene.

VLDLR LDLR LRP1

2.55e-06911037544347
Pubmed

Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues.

FBN2 LTBP1 POGLUT2

2.55e-069110338844137
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

SSPOP CRB1 FBN2 LRP1 LRP2

3.18e-0671110533541421
Pubmed

A human MAP kinase interactome.

VWF ARID4B LAMB1 LAMB2 TRIM21 AP2B1 TRIM28 HPS4 AKAP13 NUP153

3.49e-064861101020936779
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

VWF LAMB1 LAMB2 FBN2 COL14A1 LTBP1

4.71e-06135110628675934
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP1B LRP1 LRP2

4.99e-0611110324639464
Pubmed

Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.

TRIM21 FBXL19 FBXO2 FBXL4 FBXL20

7.74e-0685110519028597
Pubmed

Striking differences of LDL receptor-related protein 1B expression in mouse and human.

LRP1B LRP1

9.91e-062110215963947
Pubmed

MacroH2A1 and ATM Play Opposing Roles in Paracrine Senescence and the Senescence-Associated Secretory Phenotype.

MACROH2A1 ATM

9.91e-062110226300260
Pubmed

A neuronal VLDLR variant lacking the third complement-type repeat exhibits high capacity binding of apoE containing lipoproteins.

VLDLR LDLR

9.91e-062110219393635
Pubmed

Low density lipoprotein receptor-related protein polymorphisms are not risk factors for venous thromboembolism.

LDLR LRP1

9.91e-062110217889283
Pubmed

Differential glycosylation regulates processing of lipoprotein receptors by gamma-secretase.

LRP8 LRP1

9.91e-062110212871934
Pubmed

Upregulation of hepatic LDL transport by n-3 fatty acids in LDL receptor knockout mice.

LDLR LRP1

9.91e-062110211971949
Pubmed

ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin.

TRIM28 ATM

9.91e-062110218657500
Pubmed

Macrophage-Specific Expression of IL-37 in Hyperlipidemic Mice Attenuates Atherosclerosis.

IL37 LDLR

9.91e-062110229030487
Pubmed

The reelin receptors VLDLR and ApoER2 regulate sensorimotor gating in mice.

VLDLR LRP8

9.91e-062110217261317
Pubmed

The alpha -chains of C4b-binding protein mediate complex formation with low density lipoprotein receptor-related protein.

LRP1 C4BPA

9.91e-062110211705989
Pubmed

Defective ATM-Kap-1-mediated chromatin remodeling impairs DNA repair and accelerates senescence in progeria mouse model.

TRIM28 ATM

9.91e-062110223173799
Pubmed

The C-terminal region of laminin beta chains modulates the integrin binding affinities of laminins.

LAMB1 LAMB2

9.91e-062110219147489
Pubmed

LRP: role in vascular wall integrity and protection from atherosclerosis.

LDLR LRP1

9.91e-062110212690199
Pubmed

ApoER2 and VLDLR in the developing human telencephalon.

VLDLR LRP8

9.91e-062110221601501
Pubmed

ATM, KAP1 and the Epstein-Barr virus polymerase processivity factor direct traffic at the intersection of transcription and replication.

TRIM28 ATM

9.91e-062110237852757
Pubmed

Genome-wide association study of irritable vs. elated mania suggests genetic differences between clinical subtypes of bipolar disorder.

SLITRK1 SLITRK6

9.91e-062110223326512
Pubmed

Crystal structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptor.

VWF ANTXR2

9.91e-062110215079089
Pubmed

Differential Action of Reelin on Oligomerization of ApoER2 and VLDL Receptor in HEK293 Cells Assessed by Time-Resolved Anisotropy and Fluorescence Lifetime Imaging Microscopy.

VLDLR LRP8

9.91e-062110230873003
Pubmed

Forced expression of laminin beta1 in podocytes prevents nephrotic syndrome in mice lacking laminin beta2, a model for Pierson syndrome.

LAMB1 LAMB2

9.91e-062110221876163
Pubmed

Augmented Th17 differentiation in Trim21 deficiency promotes a stable phenotype of atherosclerotic plaques with high collagen content.

TRIM21 LDLR

9.91e-062110229016728
Pubmed

Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants.

LDLR LRP1

9.91e-06211029449704
Pubmed

LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome.

LDLR LRP1

9.91e-062110217505534
Pubmed

Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.

LRP1 LRP2

9.91e-062110234445520
Pubmed

Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor.

VLDLR LDLR

9.91e-062110210024503
Pubmed

The Reelin receptors Apoer2 and Vldlr coordinate the patterning of Purkinje cell topography in the developing mouse cerebellum.

VLDLR LRP8

9.91e-062110218301736
Pubmed

A Mechanism-Based Targeted Screen To Identify Epstein-Barr Virus-Directed Antiviral Agents.

TRIM28 ATM

9.91e-062110232796077
Pubmed

Role for KAP1 serine 824 phosphorylation and sumoylation/desumoylation switch in regulating KAP1-mediated transcriptional repression.

TRIM28 ATM

9.91e-062110217942393
Pubmed

LDL receptor deficiency unmasks altered VLDL triglyceride metabolism in VLDL receptor transgenic and knockout mice.

VLDLR LDLR

9.91e-062110211108739
Pubmed

The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer.

P3H3 P3H2

9.91e-062110219436308
Pubmed

Clearance of coagulation factor VIII in very low-density lipoprotein receptor knockout mice.

VLDLR LRP1

9.91e-062110215327526
Pubmed

Chloroquine triggers Epstein-Barr virus replication through phosphorylation of KAP1/TRIM28 in Burkitt lymphoma cells.

TRIM28 ATM

9.91e-062110228249048
Pubmed

An extrahepatic receptor-associated protein-sensitive mechanism is involved in the metabolism of triglyceride-rich lipoproteins.

LDLR LRP1

9.91e-062110210575007
Pubmed

VLDLR and ApoER2 are receptors for multiple alphaviruses.

VLDLR LRP8

9.91e-062110234929721
Pubmed

Switch in Laminin β2 to Laminin β1 Isoforms During Aging Controls Endothelial Cell Functions-Brief Report.

LAMB1 LAMB2

9.91e-062110229599141
Pubmed

A new low density lipoprotein receptor homologue with 8 ligand binding repeats in brain of chicken and mouse.

LDLR LRP8

9.91e-06211028662771
Pubmed

Localized reduction of atherosclerosis in von Willebrand factor-deficient mice.

VWF LDLR

9.91e-062110211520791
Pubmed

LEPREL1, a novel ER and Golgi resident member of the Leprecan family.

P3H3 P3H2

9.91e-062110215063763
Pubmed

LDL-receptor mRNA expression in men is downregulated within an hour of an acute fat load and is influenced by genetic polymorphism.

LDLR LRP1

9.91e-062110217709443
Pubmed

Cellular uptake of C4b-binding protein is mediated by heparan sulfate proteoglycans and CD91/LDL receptor-related protein.

LRP1 C4BPA

9.91e-062110218266273
Pubmed

Reversal of hypercholesterolemia in low density lipoprotein receptor knockout mice by adenovirus-mediated gene transfer of the very low density lipoprotein receptor.

VLDLR LDLR

9.91e-06211028636110
Pubmed

Notch signaling in kidney development.

JAG2 NOTCH2

9.91e-062110212496659
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

DDX47 VLDLR ARID4B P3H3 LAMB1 MACROH2A1 LDLR FBN2 TRIM28 VANGL1 LRP1 LRP2 LTK NOTCH2

1.19e-0511161101431753913
Pubmed

Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.

PRAMEF7 PRAMEF12 PRAMEF8

2.03e-0517110323565261
Pubmed

Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.

PRAMEF7 PRAMEF12 PRAMEF8

2.03e-0517110337781892
Pubmed

Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins.

SLITRK4 SLITRK3 SLITRK1 SLITRK6

2.28e-0552110424613359
Pubmed

The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.

PRAMEF7 PRAMEF12 PRAMEF8

2.43e-0518110323894331
Pubmed

Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.

PRAMEF7 PRAMEF12 PRAMEF8

2.43e-0518110339181896
Pubmed

Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.

PRAMEF7 PRAMEF12 PRAMEF8

2.43e-0518110312890732
Pubmed

Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.

PRAMEF7 PRAMEF12 PRAMEF8

2.43e-0518110329731491
Pubmed

Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.

PRAMEF7 PRAMEF12 PRAMEF8

2.43e-0518110314675769
Pubmed

Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.

PRAMEF7 PRAMEF12 PRAMEF8

2.87e-0519110328604677
Pubmed

Reelin together with ApoER2 regulates interneuron migration in the olfactory bulb.

VLDLR LRP8

2.97e-053110223209795
Pubmed

The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2.

VLDLR LRP8

2.97e-053110220427281
Pubmed

Hepatic remnant lipoprotein clearance by heparan sulfate proteoglycans and low-density lipoprotein receptors depend on dietary conditions in mice.

LDLR LRP1

2.97e-053110223846497
Pubmed

Inactivation of the LRP1 intracellular NPxYxxL motif in LDLR-deficient mice enhances postprandial dyslipidemia and atherosclerosis.

LDLR LRP1

2.97e-053110219667105
Pubmed

Identification of mutations in the gene encoding lamins A/C in autosomal dominant limb girdle muscular dystrophy with atrioventricular conduction disturbances (LGMD1B).

LAMB1 LAMB2

2.97e-053110210814726
InteractionNTN5 interactions

LRP1B LDLR JAG2 FBN2 LRP2 LTBP1 NOTCH2

2.93e-11241067int:NTN5
InteractionIGFL3 interactions

VLDLR LAMB1 LAMB2 LRP1B LDLR JAG2 FBN2 LRP2 NOTCH2

2.05e-10751069int:IGFL3
InteractionZFP41 interactions

LRP1B LDLR FBN2 LRP1 LRP2 LTBP1 NOTCH2

1.94e-08571067int:ZFP41
InteractionZNF408 interactions

VLDLR FSD2 LRP1B LDLR FBN2 LRP2 LTBP1 NOTCH2

9.85e-071451068int:ZNF408
InteractionLDLRAP1 interactions

LDLR AP1B1 AP2B1 LRP1 LRP2

1.40e-06371065int:LDLRAP1
InteractionZNF224 interactions

LRP1B FBN2 TRIM28 LRP2

3.28e-06201064int:ZNF224
InteractionST14 interactions

VLDLR LAMB1 LDLR FBXO2 JAG2 FBN2 P2RX2 NOTCH2

1.38e-052071068int:ST14
InteractionANKRD36B interactions

VLDLR LRP1B VANGL1 LRP1 LRP2

1.59e-05601065int:ANKRD36B
InteractionPRG2 interactions

MAN2B1 P3H3 LAMB2 LDLR JAG2 FBN2 VANGL1 POGLUT2 NOTCH2

1.98e-052851069int:PRG2
InteractionPLAT interactions

LRP1B F10 FBXO2 LRP1 NOTCH2

2.02e-05631065int:PLAT
InteractionEDN3 interactions

P3H3 LAMB2 LDLR JAG2 POGLUT2 NOTCH2

2.28e-051081066int:EDN3
InteractionFBN2 interactions

SVEP1 FBXO2 FBN2 LTBP1 NOTCH2

2.35e-05651065int:FBN2
InteractionPDIA4 interactions

VLDLR VWF P3H3 LAMB1 TRIM21 LDLR FBN2 LRP2 COL14A1 LTK POGLUT2

3.60e-0546810611int:PDIA4
InteractionFIBIN interactions

MAN2B1 P3H3 LAMB1 LAMB2 JAG2

3.62e-05711065int:FIBIN
InteractionGREM2 interactions

LDLR FBN2 LRP2 NOTCH2

4.18e-05371064int:GREM2
InteractionCACNA1A interactions

KDM5B VWF LAMB1 JAG2 LRP1 LTBP1

4.74e-051231066int:CACNA1A
InteractionINSIG1 interactions

AMFR ARID4B LAMB1 TRIM21 LDLR RNF139

5.67e-051271066int:INSIG1
InteractionFBXO2 interactions

MAN2B1 LAMB1 LAMB2 LRP1B FBXO2 JAG2 FBN2 LRP2 COL14A1 NOTCH2

6.23e-0541110610int:FBXO2
InteractionSNX17 interactions

VLDLR LDLR LRP8 LRP1 LRP2

6.83e-05811065int:SNX17
InteractionSCN3A interactions

LRP8 LRP1 LRP2

7.54e-05161063int:SCN3A
InteractionTMEM25 interactions

P3H3 LAMB1 LAMB2 FBXO2 COL14A1 POGLUT2

7.64e-051341066int:TMEM25
InteractionPLAUR interactions

P3H3 TATDN2 LAMB2 LRP1B LRP1 NOTCH2

7.97e-051351066int:PLAUR
InteractionPRAMEF8 interactions

PRAMEF12 PRAMEF8

8.19e-0531062int:PRAMEF8
InteractionLRP1B interactions

LRP1B LDLR FBXO2 LRP1 LRP2

8.60e-05851065int:LRP1B
InteractionWNT3A interactions

LDLR JAG2 LRP1 NOTCH2

1.28e-04491064int:WNT3A
InteractionPRG3 interactions

LDLR FBN2 POGLUT2 NOTCH2

1.28e-04491064int:PRG3
InteractionFOXD4L6 interactions

LRP1B LDLR FBN2 NOTCH2

1.28e-04491064int:FOXD4L6
InteractionCCN6 interactions

DDX47 LDLR NOTCH2

1.29e-04191063int:CCN6
InteractionAP5S1 interactions

LDLR COPS7B ZFYVE26

1.29e-04191063int:AP5S1
InteractionTSHR interactions

ASPHD1 LAMB1 LAMB2 JAG2 COMMD4

1.53e-04961065int:TSHR
InteractionMFAP5 interactions

VWF LDLR JAG2 FBN2

1.61e-04521064int:MFAP5
InteractionCD14 interactions

MAN2B1 LAMB1 TRIM21 FBXO2

1.61e-04521064int:CD14
InteractionZNF486 interactions

LDLR TRIM28

1.63e-0441062int:ZNF486
InteractionEGFL6 interactions

LRP1B LDLR LRP2

1.76e-04211063int:EGFL6
InteractionDAB1 interactions

VLDLR LDLR LRP8 LRP1 LRP2

2.54e-041071065int:DAB1
InteractionPRAMEF12 interactions

PRAMEF12 PRAMEF8

2.71e-0451062int:PRAMEF12
InteractionAMBN interactions

TRIM28 LRP2

2.71e-0451062int:AMBN
InteractionF8 interactions

VWF F10 LRP1

2.99e-04251063int:F8
InteractionGGH interactions

MAN2B1 ARID4B P3H3 LAMB1 LAMB2 FBXL19 POGLUT2

3.01e-042431067int:GGH
InteractionHRG interactions

P3H3 TRIM21 LRP1B FBN2

3.39e-04631064int:HRG
GeneFamilyLow density lipoprotein receptors

VLDLR LRP1B LDLR LRP8 LRP1 LRP2

7.56e-1213766634
GeneFamilyF-box and leucine rich repeat proteins

FBXL19 FBXL4 FBXL20

8.99e-0521763558
GeneFamilyPRAME family

PRAMEF7 PRAMEF12 PRAMEF8

1.36e-0424763686
GeneFamilyLaminin subunits

LAMB1 LAMB2

1.12e-0312762626
GeneFamilyAT-rich interaction domain containing

KDM5B ARID4B

1.77e-0315762418
CoexpressionNABA_ECM_GLYCOPROTEINS

VWF LAMB1 LAMB2 SSPOP SVEP1 FBN2 C4BPA LTBP1 CCN3

1.18e-071911109MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

VWF LAMB1 LAMB2 SSPOP SVEP1 FBN2 LTBP1 FBN3 CCN3

1.47e-071961109M3008
CoexpressionNABA_CORE_MATRISOME

VWF LAMB1 LAMB2 SSPOP SVEP1 FBN2 COL14A1 C4BPA LTBP1 CCN3

2.16e-0727011010MM17057
CoexpressionNABA_CORE_MATRISOME

VWF LAMB1 LAMB2 SSPOP SVEP1 FBN2 COL14A1 LTBP1 FBN3 CCN3

2.56e-0727511010M5884
CoexpressionGSE42724_NAIVE_VS_MEMORY_BCELL_DN

MACROH2A1 CD83 LDLR DENND6B ANKIB1 PPIP5K2 NUP153

2.22e-052001107M9793
CoexpressionGSE7831_UNSTIM_VS_CPG_STIM_PDC_4H_DN

AMFR P3H3 LDLR ADAM28 RGN HPS4 ZFYVE19

2.22e-052001107M6954
CoexpressionNABA_MATRISOME

VWF P3H3 IL37 LAMB1 LAMB2 SSPOP F10 ADAM28 SVEP1 FBN2 P3H2 COL14A1 LTBP1 FBN3 CCN3

2.55e-05102611015M5889
CoexpressionMIKKELSEN_NPC_ICP_WITH_H3K4ME3

PRAMEF7 LAMB2 PRAMEF12 PRAMEF8 IFIT2 SLITRK1 LRP1 ZFYVE26 SLITRK6 ZNF239

4.74e-0549711010MM863
CoexpressionGSE21033_CTRL_VS_POLYIC_STIM_DC_6H_DN

AMHR2 KDM5B AANAT WDR27 TBC1D10C ZFYVE26

5.38e-051571106M7733
CoexpressionDESCARTES_ORGANOGENESIS_SCHWANN_CELL_PRECURSOR

PRAMEF7 PRAMEF12 PRAMEF8 IFIT2 SLITRK6

5.91e-05981105MM3656
CoexpressionNABA_MATRISOME

VWF P3H3 LAMB1 LAMB2 SSPOP F10 ADAM28 SVEP1 FBN2 P3H2 COL14A1 C4BPA LTBP1 CCN3

8.39e-05100811014MM17056
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 ZAN ANO5 SSPOP LRP1B LOXHD1 FBN2 LRP2

1.93e-0818411082cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 ZAN ANO5 SSPOP LRP1B LOXHD1 FBN2 LRP2

1.93e-081841108ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 ZAN ANO5 SSPOP LRP1B LOXHD1 FBN2 LRP2

1.93e-0818411082b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 ABCC9 SVEP1 LOXHD1 ANTXR2 LRP1 COL14A1 LTBP1

3.15e-081961108a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 ABCC9 SVEP1 LOXHD1 ANTXR2 LRP1 COL14A1 LTBP1

3.15e-0819611083e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FAT4 P3H3 LAMB2 SVEP1 LRP1 COL14A1 SLITRK6 CCN3

3.54e-08199110895d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 ABCC9 SVEP1 ANTXR2 LRP1 COL14A1 LTBP1

4.56e-071891107c734e5693808a0333139e87bd5be2597a9252afe
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 LOXHD1 ANTXR2 LRP1 COL14A1 LTBP1

4.73e-0719011072306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 ABCC9 SVEP1 ANTXR2 LRP1 COL14A1 LTBP1

4.73e-0719011072e592323085ba9c019d678ac2a784462ab470ed9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 LOXHD1 ANTXR2 LRP1 COL14A1 LTBP1

4.73e-0719011071f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 ABCC9 SVEP1 ANTXR2 LRP1 COL14A1 LTBP1

4.73e-071901107445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 LOXHD1 ANTXR2 LRP1 COL14A1 LTBP1

4.90e-071911107a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 ABCC9 SVEP1 ANTXR2 LRP1 COL14A1 LTBP1

4.90e-071911107c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 ABCC9 SVEP1 ANTXR2 LRP1 COL14A1 LTBP1

4.90e-071911107cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VLDLR P3H3 LAMB1 SVEP1 LRP1 COL14A1 LTBP1

4.90e-071911107997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 LOXHD1 ANTXR2 LRP1 COL14A1 LTBP1

5.07e-0719211079093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 LOXHD1 ANTXR2 LRP1 COL14A1 LTBP1

5.07e-0719211079ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

P3H3 LAMB1 ABCC9 SVEP1 LRP1 COL14A1 LTBP1

5.07e-0719211077b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P3H3 LAMB1 LAMB2 SVEP1 ANTXR2 LRP1 COL14A1

5.07e-071921107beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCellfacs-Lung-3m-Mesenchymal|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

P3H3 LAMB1 ABCC9 SVEP1 LRP1 COL14A1 LTBP1

5.07e-0719211078df15085b35b86f39debd933284cb703c5dd63c2
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

P3H3 LAMB1 ABCC9 SVEP1 LRP1 COL14A1 LTBP1

5.07e-07192110732acd89617934016cd135d2cc797e8e79ae1b37f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 LOXHD1 ANTXR2 LRP1 COL14A1 LTBP1

5.25e-071931107f1199518c3626fd29bfce65070dd21a660671213
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P3H3 LAMB1 ABCC9 SVEP1 LRP1 COL14A1 LTBP1

5.25e-071931107d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR P3H3 LAMB1 SVEP1 LRP1 COL14A1 LTBP1

5.44e-071941107da926441053b499cb5107ccb116fb1b3844d82b7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 LOXHD1 ANTXR2 LRP1 COL14A1 LTBP1

5.44e-071941107240d122dcb9dd1ab2867503ad85869853adcacae
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 LOXHD1 ANTXR2 LRP1 COL14A1 LTBP1

5.44e-071941107ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR P3H3 LAMB1 SVEP1 LRP1 COL14A1 LTBP1

5.44e-07194110754a7f693966b5c02f6b248950ddb5fa32af3ae67
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR P3H3 LAMB1 SVEP1 LRP1 COL14A1 LTBP1

5.44e-071941107f34b3bbdebf56f66ff499e390e5515a4a4093f90
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR P3H3 LAMB1 LAMB2 SVEP1 COL14A1 LTBP1

5.63e-07195110769a29d03e664b72f32d41876510c62345c3aed31
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

P3H3 LAMB1 F10 SVEP1 LRP1 COL14A1 LTBP1

5.63e-0719511071236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCellfacs-GAT-Fat-3m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR P3H3 LAMB1 LAMB2 SVEP1 COL14A1 LTBP1

5.63e-0719511071cffae2b08dbfa1c633ce24023e89b66d28b5431
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 LOXHD1 ANTXR2 LRP1 COL14A1 LTBP1

5.63e-07195110744d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR P3H3 LAMB1 LAMB2 SVEP1 COL14A1 LTBP1

5.63e-0719511079cef6f18664518060af7c192310dddce6d70345a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 LOXHD1 ANTXR2 LRP1 COL14A1 LTBP1

5.83e-071961107ba869f7a86f37fd6d84d6ad69baca0e0faaf5887
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 LOXHD1 ANTXR2 LRP1 COL14A1 LTBP1

5.83e-07196110730ad56d49000e4ddce73b4443b3994564bd1e2d6
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P3H3 LAMB1 LAMB2 ABCC9 LRP1 COL14A1 LTBP1

5.83e-071961107b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P3H3 LAMB1 LAMB2 ABCC9 LRP1 COL14A1 LTBP1

5.83e-071961107787c6cd92035e0b1108c2c086c42a229016e476b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 LOXHD1 ANTXR2 LRP1 COL14A1 LTBP1

6.03e-0719711076d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 LOXHD1 ANTXR2 LRP1 COL14A1 LTBP1

6.03e-071971107b349f8e96d61a4c296af64711e11fc44459a9413
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 LOXHD1 ANTXR2 LRP1 COL14A1 LTBP1

6.03e-071971107c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB1 ADAM28 SVEP1 FBN2 LRP1 COL14A1 SLITRK6

6.45e-07199110784545ced0c792bc77980a50d65e484eab648d47e
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 F10 SVEP1 RGN LRP1 COL14A1 LTBP1

6.45e-071991107fb580e9321ddf97c73b2e356cd82523db74a38a2
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KLHL6 RNF135 MACROH2A1 CD83 STAB1 AP1B1 LRP1

6.67e-07200110778d75d381cb2b9a4c9eb7c32a07b014eaee39195
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB1 ADAM28 SVEP1 FBN2 LRP1 COL14A1 SLITRK6

6.67e-072001107ac8a5d71acd4d401995babd233f0d3738e8ad2a5
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1B SVEP1 CRB1 FBN2 SPHKAP LRP2

2.91e-061601106c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1B SVEP1 CRB1 FBN2 SPHKAP LRP2

2.91e-06160110625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 ANTXR2 LRP1 COL14A1 LTBP1

3.35e-06164110601a7c335897128d3478b8b9b44fb461cab493084
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

LAMB1 LRP1B SVEP1 LRP1 COL14A1 LTBP1

5.03e-0617611062e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

LAMB1 LRP1B SVEP1 LRP1 COL14A1 LTBP1

5.03e-061761106f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 ANTXR2 LRP1 COL14A1 LTBP1

5.72e-061801106ea7a1ccf0dd3bb5af5df87501f873e7339a824b3
ToppCellCOVID-19-kidney-Bcells|kidney / Disease (COVID-19 only), tissue and cell type

KLHL6 ACAP1 CD83 NIBAN3 ADAM28 TBC1D10C

5.72e-0618011065650fc7ebcdf5e0be9a217a58d36a8386d59fd1b
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

P3H3 LAMB1 ABCC9 SVEP1 LRP1 COL14A1

5.91e-0618111063462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

P3H3 LAMB1 ABCC9 SVEP1 LRP1 COL14A1

5.91e-0618111066730e249cac55ae892cc567d9211615882f3dab4
ToppCellCOVID-19-lung-B_cells|COVID-19 / Disease (COVID-19 only), tissue and cell type

ACAP1 CD83 NIBAN3 ADAM28 TBC1D10C ATM

6.70e-061851106e8f1ad580f19705b5ca1d7d8867b2125f4891684
ToppCellnormal_Lung-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

ACAP1 NIBAN3 ANTXR2 P3H2 TRAPPC10 FBXL20

7.12e-061871106a3592f056e1c2f82ba325fea2ecc4dd6c6347c81
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 SVEP1 FBN2 ANTXR2 LRP2 COL14A1

7.12e-0618711064e553721fa5598cb211f44e3226280b7e6885484
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 SVEP1 FBN2 ANTXR2 LRP2 COL14A1

7.12e-061871106d36e7fc6125e7a4310499365022d38f34b757a73
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 SVEP1 FBN2 ANTXR2 LRP2 COL14A1

7.12e-061871106827eae63fabf6892a82ce7779b5f395958d3d628
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-naive_B_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ACAP1 CD83 NIBAN3 TBC1D10C TRAPPC10 AKAP13

8.03e-061911106a073d58154c801ec499fd969f42b7f1ee7f15d79
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR P3H3 LAMB1 SVEP1 LRP1 LTBP1

8.03e-0619111066cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCelldroplet-Fat-Gat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR P3H3 LAMB1 SVEP1 LRP1 LTBP1

8.03e-061911106850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

AMHR2 ASPHD1 SLITRK4 ANO5 LRP8 LRP2

8.03e-0619111064c4eb61e6179d2f8fc524d2f813db9cba84f67a2
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR P3H3 LAMB1 SVEP1 LRP1 LTBP1

8.03e-0619111068b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 ANTXR2 LRP1 COL14A1 LTBP1

8.03e-061911106806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellfacs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P3H3 LAMB1 ABCC9 SVEP1 LRP1 COL14A1

8.28e-061921106a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 SVEP1 FBN2 ANTXR2 COL14A1 LTBP1

8.28e-0619211068937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCellfacs-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P3H3 LAMB1 ABCC9 SVEP1 LRP1 COL14A1

8.28e-061921106eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 SVEP1 FBN2 ANTXR2 COL14A1 LTBP1

8.28e-061921106e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB1 SVEP1 FBN2 ANTXR2 COL14A1 LTBP1

8.28e-061921106ac1477433704573f95111eee6263b93668d2845e
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

VLDLR FAT4 F10 SVEP1 COL14A1 LTBP1

8.28e-061921106e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR LAMB1 SVEP1 ANTXR2 LRP1 LTBP1

8.28e-0619211062d9e2262f1342fe17735f21f733c029d1275e955
ToppCelldroplet-Fat-Mat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR P3H3 LAMB1 SVEP1 LRP1 COL14A1

8.53e-061931106ebd090d7801480b3cee45caac3d30cc991836769
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR P3H3 LAMB1 SVEP1 LRP1 COL14A1

8.53e-06193110622c58032e58730715224d7934968ce92d150b0e8
ToppCellfacs-MAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P3H3 LAMB2 ABCC9 SVEP1 LRP1 COL14A1

8.53e-061931106f95b95c58a6edb8a03dd15ae166f47f9f33d8bd6
ToppCellfacs-MAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P3H3 LAMB2 ABCC9 SVEP1 LRP1 COL14A1

8.53e-06193110685faf6c5ce4769615a4eca036e2ba307e176bb52
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR P3H3 LAMB1 SVEP1 LRP1 COL14A1

8.53e-061931106573ad2f848bede1fe20c7b4b352a9242ec294725
ToppCellfacs-MAT-Fat-3m-Mesenchymal|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P3H3 LAMB2 ABCC9 SVEP1 LRP1 COL14A1

8.53e-061931106110a7d2ba7d066c2be38be98b643b76c520dd980
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 ANTXR2 LRP1 COL14A1 LTBP1

9.04e-061951106d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 ANTXR2 LRP1 COL14A1 LTBP1

9.04e-061951106d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 LOXHD1 ANTXR2 COL14A1 LTBP1

9.04e-061951106803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 SVEP1 P2RX2 LRP1 COL14A1 LTBP1

9.04e-061951106f54bc4454270ff06e85596f98199372b50d0179f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 LOXHD1 ANTXR2 COL14A1 LTBP1

9.04e-061951106cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 ANTXR2 LRP1 COL14A1 LTBP1

9.04e-0619511063c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 LOXHD1 ANTXR2 COL14A1 LTBP1

9.04e-061951106783bfa8110161cbd6def50ce849cae676c39c458
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 LOXHD1 ANTXR2 COL14A1 LTBP1

9.04e-0619511064f70157d42a16ff0259bc24a62803c4df4285c44
ToppCellfacs-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

P3H3 LAMB1 LAMB2 ABCC9 COL14A1 NOTCH2

9.04e-061951106c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCellfacs-Trachea-18m-Mesenchymal|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

P3H3 LAMB2 SVEP1 LRP1 COL14A1 LTBP1

9.04e-0619511060d1876f6fdc1eafeb60d6fd7da5bce737d2b4a5a
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

P3H3 LAMB1 SVEP1 LRP1 COL14A1 LTBP1

9.31e-061961106d4676a6b0d9e417795fc9a6bcb1762d3dd656ca9
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

LAMB2 LDLR VANGL1 P3H2 LTBP1 NOTCH2

9.58e-06197110661749ccafeb938c310cff1de5ff924a1c794325a
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B-B_cell-B_naive|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ACAP1 FSD2 CD83 NIBAN3 ADAM28 TBC1D10C

9.58e-061971106fd65020089baca78334cecddc96b7a65028c2b7c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KLHL6 MAN2B1 CD83 SSPOP AP1B1 AKAP13

9.58e-061971106b597c292fc1cb381a4325fed15a32966c38def28
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 ANTXR2 LRP1 COL14A1 LTBP1

9.58e-061971106ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMB1 ABCC9 LRP1B F10 SVEP1 COL14A1

9.58e-0619711063bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC9 SVEP1 ANTXR2 LRP1 COL14A1 LTBP1

9.58e-06197110637f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCC9 F10 SVEP1 LRP1 COL14A1 LTBP1

9.58e-06197110671786e9432e2d649f5d86f639abb25e7102deb67
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

LAMB2 LDLR VANGL1 P3H2 LTBP1 NOTCH2

9.58e-0619711069d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMB1 ABCC9 LRP1B F10 SVEP1 COL14A1

9.58e-06197110617344464fdcc5ba0c03959696b97c195f11e644c
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMB1 ABCC9 LRP1B F10 SVEP1 COL14A1

9.58e-0619711065b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCellBiopsy_IPF-Immune-B_cells|Biopsy_IPF / Sample group, Lineage and Cell type

ACAP1 CD83 NIBAN3 ADAM28 TBC1D10C ATM

9.86e-0619811066a519337a4932a7b685fe7defd3de24fa2016b7d
ToppCellBronchus_Control_(B.)-Immune-TX-B_cells|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

ACAP1 CD83 NIBAN3 ADAM28 TBC1D10C ATM

9.86e-0619811066231c44a909dd06f85c8210814e976a5f29148d0
ComputationalMetal / Ca ion binding.

LDLR F10 CRB1 RGN FBN2 LRP1 LTBP1

1.96e-05133687MODULE_324
ComputationalGenes in the cancer module 236.

VLDLR LDLR LRP8

1.85e-0418683MODULE_236
ComputationalNeighborhood of LTK

AMFR AANAT ATM LTK

1.96e-0446684GCM_LTK
ComputationalFetal liver genes - metabolism and xenobiotics.

AANAT LAMB2 LDLR F10 STAB1 RGN FBN2 LRP1 C4BPA SMOX

5.18e-044536810MODULE_24
ComputationalNeighborhood of ATM

AANAT ATM LTK

6.35e-0427683GCM_ATM
Drug0316684-0000 [391209-55-5]; Down 200; 10uM; PC3; HT_HG-U133A

AMFR TRIM21 IFIT2 AP2B1 AKAP13 ATM NOTCH2 TMEM63A

4.69e-0619411087098_DN
DrugAceclofenac [89796-99-6]; Up 200; 11.2uM; PC3; HT_HG-U133A

AMFR ABCC9 AP2B1 TRAPPC10 AKAP13 LTBP1 NOTCH2 TMEM63A

5.25e-0619711082117_UP
Diseaseconnective tissue disease (implicated_via_orthology)

FBN2 FBN3

3.61e-0531032DOID:65 (implicated_via_orthology)
DiseaseLDL cholesterol change measurement

PKD1L3 LDLR

2.51e-0471032EFO_0007804
Diseasedementia (is_implicated_in)

VLDLR LRP8

7.78e-04121032DOID:1307 (is_implicated_in)
Diseasefamilial hyperlipidemia (implicated_via_orthology)

LDLR RGN

7.78e-04121032DOID:1168 (implicated_via_orthology)
Diseasemean platelet volume

VWF ZAN MACROH2A1 SVEP1 COMMD4 AP1B1 AP2B1 KIF28P C4BPA LTBP1 FBXL20

8.77e-04102010311EFO_0004584
DiseaseAlzheimer's disease (is_implicated_in)

VLDLR LDLR LRP8 LRP1

1.20e-031321034DOID:10652 (is_implicated_in)
DiseaseNeoplasm of uncertain or unknown behavior of bladder

ATM NOTCH2

1.23e-03151032C0496930
DiseaseProteinuria

VWF LRP2

1.23e-03151032HP_0000093
DiseaseBenign neoplasm of bladder

ATM NOTCH2

1.23e-03151032C0154017
DiseaseCarcinoma in situ of bladder

ATM NOTCH2

1.23e-03151032C0154091
DiseaseCarcinoma of bladder

ATM NOTCH2

1.78e-03181032C0699885
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

LRP1B AKAP13 ATM RNF139

1.83e-031481034C0279702
Diseasebreast cancer (is_implicated_in)

KDM5B F10 ADAM28 ATM

1.92e-031501034DOID:1612 (is_implicated_in)
Diseasecoagulation factor measurement

VWF F10

2.20e-03201032EFO_0004634
Diseaseesophagus squamous cell carcinoma (is_marker_for)

KDM5B PAGR1 ATM

2.24e-03741033DOID:3748 (is_marker_for)
Diseaseamino acid measurement

FAT4 VWF LAMB1 ADAM28 RP1L1 LRP2 COL14A1 LTBP1

2.62e-036781038EFO_0005134
Diseasebeta-aminoisobutyric acid measurement

NT5DC1 FBN3

3.17e-03241032EFO_0010464

Protein segments in the cluster

PeptideGeneStartEntry
ILWRDELEPCGTICE

VANGL1

136

Q8TAA9
PKCEWETPEGCEQVL

C4BPA

536

P04003
WFPALVVCPDCSDEI

ARID4B

191

Q4LE39
VTDVLCEACDQLGWT

DDX47

31

Q9H0S4
LNECTEWGQIFILDC

AP2B1

211

P63010
WRSEECDPGGCLIEL

ANO5

596

Q75V66
EWCDGCEAVLLGIEQ

COPS7B

176

Q9H9Q2
QCEEGWIPPDCDDSS

ADAM28

646

Q9UKQ2
VDGCDCVAEGLWLPQ

AZIN2

361

Q96A70
AEGWTPLLAACDVRC

ASB10

246

Q8WXI3
CNSPVWGADKCEELL

MACROH2A1

276

O75367
GSWCEIDIDECLPSP

FAT4

3856

Q6V0I7
ENWCTIEPCPDAASL

AKAP13

1391

Q12802
PQEGDEVCIWECIEK

ANTXR2

471

P58335
WECLGEAHEPCDCQT

ANKIB1

466

Q9P2G1
NLDPECKCTDDRLWE

ABCC9

1406

O60706
CDCREPAPEWASINL

ACAP1

421

Q15027
LNECTEWGQIFILDC

AP1B1

211

Q10567
PCFLRWDEDECGVTL

FBN3

916

Q75N90
VWGVECEACPDPESL

FBN3

946

Q75N90
APCLEAVCSEIDQWP

DENND6B

181

Q8NEG7
DCWDADPEARLTAEC

AMHR2

486

Q16671
EELPWCCICNEDATL

ZFYVE19

416

Q96K21
AEGVINAEIPNCWEC

FBXL19

131

Q6PCT2
DWCVPCSDEEVELPA

PAGR1

86

Q9BTK6
DNCVLDPDTGECWRE

P3H3

586

Q8IVL6
DVSCTLDGCLEVPWE

NIBAN3

596

Q86XR2
ACSEDVDLPCTAPWD

CD83

26

Q01151
ECGWDGLDCAADQPE

NOTCH2

1526

Q04721
LLNVTPEDWDFCCKG

NT5DC1

51

Q5TFE4
PEDWDFCCKGLALDL

NT5DC1

56

Q5TFE4
VLCWDPEAQKLTEEC

KLHL6

576

Q8WZ60
VSQSWLCDGDPDCPD

LRP1B

46

Q9NZR2
PRAWLCDREDDCGDQ

LRP1B

941

Q9NZR2
CVPDLWRCDGEKDCE

LRP1B

1066

Q9NZR2
SKLWVCDEDPDCADA

LRP1B

3451

Q9NZR2
GWSGPTCALDIDECA

JAG2

376

Q9Y219
VDQVDGFECICPEQW

JAG2

401

Q9Y219
WEGELCDTNPNDCLP

JAG2

666

Q9Y219
GRCIPISWTCDLDDD

LRP1

946

Q07954
VCVPERWLCDGDKDC

LRP1

2786

Q07954
EPQCWAEGHCLLVDD

ASPHD1

331

Q5U4P2
LWVLGCAVELPDVSC

HPS4

91

Q9NQG7
DCEIGPIGWHCLDDK

RABIF

96

P47224
SPESCWLVEELCLAV

LOXHD1

1496

Q8IVV2
WQAELQLAECLCPEG

LTK

391

P29376
NPCGEEDLEGWCDVE

FBXO2

126

Q9UK22
GWNGQCLDVDECLEP

LTBP1

1031

Q14766
LCIVDDWICEEEITG

INTS2

721

Q9H0H0
LLAWAGVSCCELAEE

NSUN5P2

86

Q63ZY6
ECQELFWGDPDVECR

LAMB1

1116

P07942
SECQELHWGDPGLQC

LAMB2

1126

P55268
AAIWCCLEEGLEPTC

FMO6P

16

O60774
SCLQPEGDEVDWVQC

KDM5B

1491

Q9UGL1
GRCIPSEWICDGDND

LRP2

2916

P98164
ADNCLLDPEANECWK

P3H2

581

Q8IVL5
DFENELGCCPWLTAI

TMEM63A

106

O94886
DPAGCQDIWKEICQA

PPP4R3C

86

Q6ZMV5
INWDCDLDLPASECN

P2RX2

266

Q9UBL9
ELDCIQEVEVCCPWE

PRAMEF12

201

O95522
CGNWLAETCLENPAV

ATM

2341

Q13315
DWEKDEPQCCLEDPA

IL37

16

Q9NZH6
LAFWGIDETDVEPCC

KCNC1

91

P48547
WPLESFCEELCNDLF

BTAF1

281

O14981
ECCEKWICGPDEEDS

CCN3

166

P48745
ASGCPLLEELDLGWC

FBXL4

501

Q9UKA2
WANTDKCCELPGLRD

COL14A1

1426

Q05707
IWVDAAVPCLEECGF

FSCN3

166

Q9NQT6
CGDLDCPDWVLAEIS

COMMD4

6

Q9H0A8
NLCWDVLCVDQPLVE

MAN2B1

266

O00754
PELDCEEGWTRLKCG

IFIT2

136

P09913
WGDPCELCPKDDEVA

FBN2

2136

P35556
CELEIDECWSQPCLN

CRB1

221

P82279
GEWCEKDIDECASDP

CRB1

1291

P82279
ELWNADLQSEFLCPC

CT62

46

P0C5K7
CKDGECPWQALLINE

F10

241

P00742
ELDCIQEVEVCCPWE

PRAMEF8

201

Q5VWM4
VDLWGLQEGCTELSC

KIF28P

776

B7ZC32
PEEEACGVWLDAAAL

AUNIP

6

Q9H7T9
PSVWRCDEDDDCLDH

LRP8

61

Q14114
DDFWDLICNLIISGC

RNF139

271

Q8WU17
VELQLEDNPWNCSCD

SLITRK4

206

Q8IW52
IDLEGNPWDCTCDLV

SLITRK4

526

Q8IW52
PVWLAEDDLGCIICQ

RNF135

11

Q8IUD6
EDDLGCIICQGLLDW

RNF135

16

Q8IUD6
ADFEVSQCPWLPDIC

SPHKAP

141

Q2M3C7
DFCDPRTLTDCLWEE

TATDN2

536

Q93075
LCPELSLGWFEEGCL

AANAT

76

Q16613
QIDLEDNPWDCSCDL

SLITRK6

511

Q9H5Y7
DNPWDCSCDLVGLQQ

SLITRK6

516

Q9H5Y7
LGAIQLCDGVWDCPD

SSPOP

1506

A2VEC9
QWLDCAQGPASCAEL

SSPOP

3096

A2VEC9
DDIKWVCQDLDPGDC

TMEM132D

1071

Q14C87
TGIIQCLSAEDCVDW

SNTG1

241

Q9NSN8
EGCPLLEQLNISWCD

FBXL20

166

Q96IG2
SCEEAVLICWESGNL

FSD2

481

A1L4K1
ELQLEENPWNCTCEI

SLITRK3

226

O94933
QIDLNENPWDCTCDL

SLITRK3

556

O94933
LCNCWLAVDLGDCEL

PKD1L3

841

Q7Z443
PENCRCGESPVWEEV

RGN

11

Q15493
WDEDEPICIPVDCSS

SVEP1

2821

Q4LDE5
PEELAVNNDDCAICW

AMFR

331

Q9UKV5
ELDCIQEVEVCCPWE

PRAMEF7

201

Q5VXH5
QWICSNEECPGECLV

VWF

376

P04275
EILLEDNPWDCTCDL

SLITRK1

206

Q96PX8
DNPWDCTCDLLSLKE

SLITRK1

211

Q96PX8
DPVLGEVDPLCCVWE

RP1L1

356

Q8IWN7
LPPEEAFWCLVQICE

TBC1D10C

191

Q8IV04
WSVVVECEDCELIPA

SMOX

311

Q9NWM0
CCRVEEVWLAELQGP

ZNF395

116

Q9H8N7
CDEGWTGPRCEVQLE

STAB1

2041

Q9NY15
PEGSWDCELCLVQNK

NUP153

851

P49790
WEEVTCPICLDPFVE

TRIM21

11

P19474
NCDCPLQDSAAWLRE

POGLUT2

136

Q6UW63
DPWLSSCEEVDDCKD

ZNF180

146

Q9UJW8
EPVENWPLCDCLISF

PPIP5K2

86

O43314
QDCAFPLDGTELCIW

WDR27

41

A2RRH5
PGALDCWVFLSCLEV

TRAPPC10

351

P48553
SLDPIDCNCKDIHGW

ZNF239

146

Q16600
LWRDAEDGTPLCNAC

ZGLP1

216

P0C6A0
PGCDELLRDACDGLW

ZFYVE26

396

Q68DK2
GEEWSCSLCHVLPDL

TRIM28

661

Q13263
CDFEDDAKPLCDWSQ

ZAN

41

Q9Y493
IPISWVCDDDADCSD

VLDLR

206

P98155
DWSDEPLKECHINEC

VLDLR

346

P98155
IPQLWACDNDPDCED

LDLR

161

P01130