Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsodium:bicarbonate symporter activity

SLC4A7 SLC4A8 SLC4A10

3.58e-0661143GO:0008510
GeneOntologyMolecularFunctioncalcium ion binding

CACNA1E PLCZ1 CDHR1 GNPTAB PPP2R3B F2 PCDH20 RYR3 MYOF LOXL2 ITSN2 LRP4 C1S RAPGEF2 FER1L5

2.35e-0574911415GO:0005509
GeneOntologyMolecularFunctionphosphoenolpyruvate carboxykinase activity

PCK1 PCK2

3.23e-0521142GO:0004611
GeneOntologyMolecularFunctionphosphoenolpyruvate carboxykinase (GTP) activity

PCK1 PCK2

3.23e-0521142GO:0004613
GeneOntologyMolecularFunctionmonoatomic cation:bicarbonate symporter activity

SLC4A7 SLC4A8 SLC4A10

4.97e-05131143GO:0140410
GeneOntologyMolecularFunctionsodium,bicarbonate:chloride antiporter activity

SLC4A8 SLC4A10

9.66e-0531142GO:0140892
GeneOntologyMolecularFunctionkinase activity

PDGFRA MARK3 CDK11A DGKZ AK9 SIK3 PDXK NRP2 ITPKC GUCY2C BTK MARK4 DGKI PCK1

1.16e-0476411414GO:0016301
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

PDGFRA MARK3 CDK11A DGKZ SIK3 PDXK NRP2 ITPKC GUCY2C BTK MARK4 DGKI PCK1

2.05e-0470911413GO:0016773
GeneOntologyMolecularFunctiontau-protein kinase activity

MARK3 SIK3 MARK4

2.58e-04221143GO:0050321
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

PDGFRA MARK3 GNPTAB CDK11A DGKZ AK9 SIK3 PDXK NRP2 ITPKC GUCY2C BTK MARK4 DGKI PCK1

2.88e-0493811415GO:0016772
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1E SLC4A7 SLC4A8 GRIA3 GRIK2 RYR3 SLC4A10 KCNQ1 KCNQ3 KCNH5

3.34e-0446511410GO:0046873
GeneOntologyMolecularFunctionvascular endothelial growth factor receptor activity

PDGFRA NRP2

6.66e-0471142GO:0005021
GeneOntologyMolecularFunctionankyrin repeat binding

RELA TNKS1BP1

6.66e-0471142GO:0071532
GeneOntologyMolecularFunctiongated channel activity

CACNA1E GRIA3 GRIK2 RYR3 ANO8 KCNQ1 KCNQ3 KCNH5

6.67e-043341148GO:0022836
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC4A7 SLC4A8 SLC4A10

7.97e-04321143GO:0015106
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC4A7 SLC4A8 SLC4A10

7.97e-04321143GO:0005452
GeneOntologyMolecularFunctionATP-dependent diacylglycerol kinase activity

DGKZ DGKI

1.72e-03111142GO:0004143
GeneOntologyBiologicalProcesspropionate catabolic process

PCK1 PCK2

3.03e-0521142GO:0019543
GeneOntologyBiologicalProcessglycerol biosynthetic process from pyruvate

PCK1 PCK2

3.03e-0521142GO:0046327
GeneOntologyCellularComponentneuronal cell body

CACNA1E FLNA SLC4A8 BACE1 GRIA3 ALS2 GRIK2 SLC4A10 ARC LRP4 KCNQ1 KCNQ3 DGKI ROBO1 RAPGEF2 HCFC1

1.21e-0583511416GO:0043025
GeneOntologyCellularComponentcell body

CACNA1E FLNA SLC4A8 BACE1 GRIA3 ALS2 GRIK2 SLC4A10 ARC LRP4 KCNQ1 KCNQ3 DGKI ROBO1 RAPGEF2 HCFC1

4.41e-0592911416GO:0044297
GeneOntologyCellularComponentdendrite

FLNA SLC4A8 MARK3 BACE1 GRIA3 ALS2 GRIK2 MARK4 SLC4A10 ARC LRP4 KCNQ3 DGKI ROBO1 HCFC1

6.60e-0585811415GO:0030425
GeneOntologyCellularComponentdendritic tree

FLNA SLC4A8 MARK3 BACE1 GRIA3 ALS2 GRIK2 MARK4 SLC4A10 ARC LRP4 KCNQ3 DGKI ROBO1 HCFC1

6.77e-0586011415GO:0097447
GeneOntologyCellularComponentsomatodendritic compartment

CACNA1E FLNA SLC4A8 MARK3 BACE1 GRIA3 ALS2 GRIK2 MARK4 SLC4A10 ARC LRP4 KCNQ1 KCNQ3 DGKI ROBO1 RAPGEF2 HCFC1

1.14e-04122811418GO:0036477
GeneOntologyCellularComponentneuron to neuron synapse

SLC4A8 SIGMAR1 BACE1 GRIA3 DGKZ ALS2 GRIK2 ARC LRP4 DGKI PCBP2

1.37e-0452311411GO:0098984
GeneOntologyCellularComponentasymmetric synapse

SLC4A8 SIGMAR1 GRIA3 DGKZ ALS2 GRIK2 ARC LRP4 DGKI PCBP2

2.85e-0447711410GO:0032279
GeneOntologyCellularComponentaxon

FLNA SLC4A8 PDGFRA SIGMAR1 BACE1 GRIA3 ALS2 GRIK2 NRP2 SLC4A10 KCNQ3 DGKI ROBO1 HCFC1

3.52e-0489111414GO:0030424
GeneOntologyCellularComponentpostsynaptic density

SIGMAR1 GRIA3 DGKZ ALS2 GRIK2 ARC LRP4 DGKI PCBP2

8.22e-044511149GO:0014069
GeneOntologyCellularComponentpostsynapse

CACNA1E FLNA SIGMAR1 GRIA3 DGKZ ALS2 GRIK2 NRP2 SLC4A10 ARC LRP4 DGKI RAPGEF2 PCBP2

1.29e-03101811414GO:0098794
GeneOntologyCellularComponentsynaptic membrane

CACNA1E SLC4A8 SIGMAR1 GRIA3 GRIK2 NRP2 ITSN2 ARC LRP4 DGKI

1.34e-0358311410GO:0097060
GeneOntologyCellularComponentpostsynaptic density membrane

SIGMAR1 GRIA3 GRIK2 ARC DGKI

1.71e-031571145GO:0098839
GeneOntologyCellularComponentpostsynaptic specialization

SIGMAR1 GRIA3 DGKZ ALS2 GRIK2 ARC LRP4 DGKI PCBP2

1.75e-035031149GO:0099572
GeneOntologyCellularComponentcation channel complex

CACNA1E GRIK2 RYR3 KCNQ1 KCNQ3 KCNH5

1.84e-032351146GO:0034703
DomainANION_EXCHANGER_2

SLC4A7 SLC4A8 SLC4A10

7.42e-0671133PS00220
DomainANION_EXCHANGER_1

SLC4A7 SLC4A8 SLC4A10

7.42e-0671133PS00219
Domain-

SLC4A7 SLC4A8 SLC4A10

1.76e-05911333.40.1100.10
DomainBand3_cytoplasmic_dom

SLC4A7 SLC4A8 SLC4A10

1.76e-0591133IPR013769
DomainBand_3_cyto

SLC4A7 SLC4A8 SLC4A10

1.76e-0591133PF07565
DomainPTrfase/Anion_transptr

SLC4A7 SLC4A8 SLC4A10

2.51e-05101133IPR016152
DomainHCO3_transpt_euk

SLC4A7 SLC4A8 SLC4A10

2.51e-05101133IPR003020
DomainHCO3_cotransp

SLC4A7 SLC4A8 SLC4A10

2.51e-05101133PF00955
DomainHCO3_transpt_C

SLC4A7 SLC4A8 SLC4A10

2.51e-05101133IPR011531
DomainTMEM183

TMEM183A TMEM183BP

3.63e-0521132IPR026509
DomainPEP_carboxykin_GTP_CS

PCK1 PCK2

3.63e-0521132IPR018091
DomainPEPCK

PCK1 PCK2

3.63e-0521132PF00821
DomainPEP_carboxykinase_GTP

PCK1 PCK2

3.63e-0521132IPR008209
DomainPEPCK_GTP

PCK1 PCK2

3.63e-0521132PS00505
DomainPEP_carboxykinase_N

PCK1 PCK2

3.63e-0521132IPR008210
DomainPEP_carboxykinase_C

PCK1 PCK2

3.63e-0521132IPR013035
Domain-

PCK1 PCK2

3.63e-05211323.90.228.20
Domain-

PCK1 PCK2

3.63e-05211323.40.449.10
DomainFerA

MYOF FER1L5

1.08e-0431132SM01200
DomainFerlin_A-domain

MYOF FER1L5

1.08e-0431132IPR012560
DomainFerA

MYOF FER1L5

1.08e-0431132PF08165
DomainMARK/par1

MARK3 MARK4

2.16e-0441132IPR033624
DomainDysFC

MYOF FER1L5

2.16e-0441132SM00694
DomainDysFN

MYOF FER1L5

2.16e-0441132SM00693
DomainPeroxin/Ferlin

MYOF FER1L5

2.16e-0441132IPR006614
DomainFerI

MYOF FER1L5

3.59e-0451132SM01202
DomainFerB

MYOF FER1L5

3.59e-0451132SM01201
DomainFerlin_B-domain

MYOF FER1L5

3.59e-0451132IPR012561
DomainFerlin_C

MYOF FER1L5

3.59e-0451132PF16165
DomainFerlin_C

MYOF FER1L5

3.59e-0451132IPR032362
DomainFerIin_dom

MYOF FER1L5

3.59e-0451132IPR012968
DomainK_chnl_volt-dep_KCNQ_C

KCNQ1 KCNQ3

3.59e-0451132IPR013821
DomainFerI

MYOF FER1L5

3.59e-0451132PF08151
DomainFerB

MYOF FER1L5

3.59e-0451132PF08150
DomainKA1

MARK3 MARK4

3.59e-0451132PF02149
DomainNa/HCO3_transpt

SLC4A8 SLC4A10

3.59e-0451132IPR003024
DomainKA1_dom

MARK3 MARK4

3.59e-0451132IPR001772
DomainK_chnl_volt-dep_KCNQ

KCNQ1 KCNQ3

3.59e-0451132IPR003937
DomainAnion_exchange

SLC4A7 SLC4A10

3.59e-0451132IPR001717
DomainKA1

MARK3 MARK4

3.59e-0451132PS50032
Domain-

MARK3 MARK4

3.59e-04511323.30.310.80
DomainKCNQ_channel

KCNQ1 KCNQ3

3.59e-0451132PF03520
DomainIg_E-set

FLNA RELA CAMTA2 PKHD1L1 TGM7

4.24e-041041135IPR014756
DomainSH3_1

ARHGAP42 ARHGEF19 AHI1 NEB BTK ITSN2

4.87e-041641136PF00018
DomainIon_trans_dom

CACNA1E RYR3 KCNQ1 KCNQ3 KCNH5

6.45e-041141135IPR005821
DomainIon_trans

CACNA1E RYR3 KCNQ1 KCNQ3 KCNH5

6.45e-041141135PF00520
DomainKA1/Ssp2_C

MARK3 MARK4

7.47e-0471132IPR028375
DomainTIG

RELA CAMTA2 PKHD1L1

8.57e-04311133PF01833
DomainIPT

RELA CAMTA2 PKHD1L1

9.41e-04321133IPR002909
DomainSH3_9

ARHGAP42 ARHGEF19 NEB ITSN2

1.28e-03781134PF14604
DomainANF_lig-bd_rcpt

GRIA3 GRIK2 GUCY2C

1.44e-03371133IPR001828
DomainANF_receptor

GRIA3 GRIK2 GUCY2C

1.44e-03371133PF01094
DomainDAGK_acc

DGKZ DGKI

1.58e-03101132PF00609
DomainDiacylglycerol_kin_accessory

DGKZ DGKI

1.58e-03101132IPR000756
DomainDAGKa

DGKZ DGKI

1.58e-03101132SM00045
DomainPeripla_BP_I

GRIA3 GRIK2 GUCY2C

1.68e-03391133IPR028082
DomainSH3

ARHGAP42 ARHGEF19 AHI1 NEB BTK ITSN2

2.02e-032161136SM00326
DomainSH3

ARHGAP42 ARHGEF19 AHI1 NEB BTK ITSN2

2.02e-032161136PS50002
DomainSH3_domain

ARHGAP42 ARHGEF19 AHI1 NEB BTK ITSN2

2.21e-032201136IPR001452
DomainUBA

MARK3 SIK3 MARK4

2.38e-03441133IPR015940
DomainEF_HAND_2

CACNA1E PLCZ1 GNPTAB PPP2R3B RYR3 ITSN2

2.82e-032311136PS50222
DomainUBA

MARK3 SIK3 MARK4

2.88e-03471133PS50030
DomainEF_hand_dom

CACNA1E PLCZ1 GNPTAB PPP2R3B RYR3 ITSN2

2.88e-032321136IPR002048
DomainDAGKc

DGKZ DGKI

3.15e-03141132SM00046
DomainC2_dom

PLCZ1 PREB MYOF ITSN2 FER1L5

3.22e-031641135IPR000008
DomainDiacylglycerol_kinase_cat_dom

DGKZ DGKI

3.62e-03151132IPR001206
DomainDAGK

DGKZ DGKI

3.62e-03151132PS50146
DomainDAGK_cat

DGKZ DGKI

3.62e-03151132PF00781
DomainNAD/diacylglycerol_kinase

DGKZ DGKI

4.65e-03171132IPR016064
DomainLig_chan-Glu_bd

GRIA3 GRIK2

5.21e-03181132PF10613
DomainGlu/Gly-bd

GRIA3 GRIK2

5.21e-03181132IPR019594
DomainLig_chan-Glu_bd

GRIA3 GRIK2

5.21e-03181132SM00918
DomainIontro_rcpt

GRIA3 GRIK2

5.21e-03181132IPR001320
DomainIono_rcpt_met

GRIA3 GRIK2

5.21e-03181132IPR001508
DomainLig_chan

GRIA3 GRIK2

5.21e-03181132PF00060
DomainPBPe

GRIA3 GRIK2

5.21e-03181132SM00079
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A7 SLC4A8 SLC4A10

2.92e-0510903M27335
PathwayREACTOME_BICARBONATE_TRANSPORTERS

SLC4A7 SLC4A8 SLC4A10

2.92e-0510903MM15073
Pubmed

Immunocytochemical identification of electroneutral Na⁺-coupled HCO₃⁻ transporters in freshly dissociated mouse medullary raphé neurons.

SLC4A7 SLC4A8 SLC4A10

3.50e-075115323500099
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

FLNA SLC4A7 SYNM COTL1 MYOF ROBO1 TNKS1BP1 HCFC1

2.32e-06256115833397691
Pubmed

A human MAP kinase interactome.

FLNA KIAA0232 TOM1L1 RELA SIK3 NEB BTK ITSN2 ROBO1 RAPGEF2

5.21e-064861151020936779
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

GPRASP1 SYNM GNPTAB TRIOBP APEH CHD9 NSUN2 CBR1 RYR3 PCSK6 AHCY LRP4 ROBO1 C1S RAPGEF2 MVP

5.28e-0612851151635914814
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

KIAA0232 GNPTAB TRIOBP ALS2 SIK3 MYOF TNKS1BP1

1.05e-05225115712168954
Pubmed

K+-Driven Cl-/HCO3- Exchange Mediated by Slc4a8 and Slc4a10.

SLC4A8 SLC4A10

1.08e-052115238674160
Pubmed

Dysregulation of phosphoenolpyruvate carboxykinase in cancers: A comprehensive analysis.

PCK1 PCK2

1.08e-052115238697449
Pubmed

Human genes encoding prothrombin and ceruloplasmin map to 11p11-q12 and 3q21-24, respectively.

CP F2

1.08e-05211523474786
Pubmed

Association of a polymorphism in the gene encoding phosphoenolpyruvate carboxykinase 1 with high-density lipoprotein and triglyceride levels.

PCK1 PCK2

1.08e-052115216132948
Pubmed

Downregulation of diacylglycerol kinase ζ enhances activation of cytokine-induced NF-κB signaling pathway.

DGKZ RELA

1.08e-052115225450975
Pubmed

Transcriptional induction of ADAMTS5 protein by nuclear factor-κB (NF-κB) family member RelA/p65 in chondrocytes during osteoarthritis development.

RELA ADAMTS5

1.08e-052115223963448
Pubmed

Bruton's tyrosine kinase is involved in p65-mediated transactivation and phosphorylation of p65 on serine 536 during NFkappaB activation by lipopolysaccharide.

RELA BTK

1.08e-052115215849198
Pubmed

Identification of 2 Potentially Relevant Gene Mutations Involved in Strabismus Using Whole-Exome Sequencing.

AHI1 NEB

1.08e-052115228391287
Pubmed

Origination and evolution of a human-specific transmembrane protein gene, c1orf37-dup.

TMEM183A TMEM183BP

1.08e-052115216644869
Pubmed

Phosphoenolpyruvate carboxykinase in cell metabolism: Roles and mechanisms beyond gluconeogenesis.

PCK1 PCK2

1.08e-052115234020084
Pubmed

KIAA0319 and ROBO1: evidence on association with reading and pleiotropic effects on language and mathematics abilities in developmental dyslexia.

KIAA0319 ROBO1

1.08e-052115224430574
Pubmed

Slit2 regulates the dispersal of oligodendrocyte precursor cells via Fyn/RhoA signaling.

PDGFRA ROBO1

1.08e-052115222433866
Pubmed

PEPCK-M expression in mouse liver potentiates, not replaces, PEPCK-C mediated gluconeogenesis.

PCK1 PCK2

1.08e-052115223466304
Pubmed

Genetic markers within glutamate receptors associated with antidepressant treatment-emergent suicidal ideation.

GRIA3 GRIK2

1.08e-052115218593792
Pubmed

Chronic continuous hypoxia decreases the expression of SLC4A7 (NBCn1) and SLC4A10 (NCBE) in mouse brain.

SLC4A7 SLC4A10

1.08e-052115217928512
Pubmed

Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease.

BACE1 RELA

1.08e-052115221329555
Pubmed

Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.

PDGFRA TRIOBP CDK11A F2 LACTB MYOF MVP

1.14e-05228115730471916
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

GPRASP1 FLNA SLC4A7 SLC4A8 VPS33A TRIOBP GRIA3 COTL1 PDXK ANO8 PREB SLC4A10 KCNQ3 PCK2

2.48e-0511391151436417873
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

FLNA SIGMAR1 VPS33A RNF149 APEH LANCL1 PDXK MYOF LOXL2 AHCY MLH1 ROBO1 TNKS1BP1 PCBP2 HCFC1

2.52e-0512971151533545068
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

SIGMAR1 MARK3 KIAA0232 TOM1L1 DMAC2 TRIOBP CHD9 TMEM183BP GRIK2 PDXK ANO8 LOXL2 ZFHX2 FOLH1B RAPGEF2 ADSS1

3.23e-0514891151628611215
Pubmed

Tumor suppressor PDCD4 inhibits NF-κB-dependent transcription in human glioblastoma cells by direct interaction with p65.

RELA PDCD4

3.24e-053115224413684
Pubmed

Proprotein convertase activation of aggrecanases in cartilage in situ.

ADAMTS5 PCSK6

3.24e-053115218671934
Pubmed

Regulation of the human NBC3 Na+/HCO3- cotransporter by carbonic anhydrase II and PKA.

SLC4A7 SLC4A8

3.24e-053115214736710
Pubmed

Hypoxia increases the rate of renal gluconeogenesis via hypoxia-inducible factor-1-dependent activation of phosphoenolpyruvate carboxykinase expression.

PCK1 PCK2

3.24e-053115232045650
Pubmed

Galactosyltransferase B4GALT1 confers chemoresistance in pancreatic ductal adenocarcinomas by upregulating N-linked glycosylation of CDK11p110.

CDK11A RELA

3.24e-053115233309857
Pubmed

Inhibition of glyceroneogenesis by histone deacetylase 3 contributes to lipodystrophy in mice with adipose tissue inflammation.

RELA PCK1

3.24e-053115221406501
Pubmed

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21.

RELA PDCD4

3.24e-053115219946272
Pubmed

Novel genes in cell cycle control and lipid metabolism with dynamically regulated binding sites for sterol regulatory element-binding protein 1 and RNA polymerase II in HepG2 cells detected by chromatin immunoprecipitation with microarray detection.

FLNA HCFC1

3.24e-053115219292868
Pubmed

Loxl2 is dispensable for dermal development, homeostasis and tumour stroma formation.

PDGFRA LOXL2

3.24e-053115229953488
Pubmed

BACE1 modulates gating of KCNQ1 (Kv7.1) and cardiac delayed rectifier KCNQ1/KCNE1 (IKs).

BACE1 KCNQ1

3.24e-053115226454161
Pubmed

The COOH termini of NBC3 and the 56-kDa H+-ATPase subunit are PDZ motifs involved in their interaction.

SLC4A7 SLC4A8

3.24e-053115212444018
Pubmed

Genetic association study of individual symptoms in depression.

GRIA3 GRIK2

3.24e-053115222429480
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

FLNA GALM ACSM1 CP NEB CBR1 COTL1 PDXK MYOF ITSN2 AHCY MVP PCK1

3.27e-0510161151319056867
Pubmed

MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1.

FLNA APEH NSUN2 PDXK MYOF MVP

3.32e-05182115630711629
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

SIGMAR1 PRDX4 GNPTAB RNF149 LANCL1 RELA GRIK2 NRP2 MYOF LOXL2 LRP4 TMEM131L ROBO1 TNKS1BP1

4.41e-0512011151435696571
Pubmed

Identification of transcripts with enriched expression in the developing and adult pancreas.

GPATCH1 CDK11A MYCBPAP COTL1 PREB TINAGL1 LOXL2 BTK ARC KCNQ1

4.43e-056241151018554416
Pubmed

Ca2+ influx via TRPC channels induces NF-kappaB-dependent A20 expression to prevent thrombin-induced apoptosis in endothelial cells.

RELA F2

6.48e-054115220032510
Pubmed

A SCL4A10 gene product maps selectively to the basolateral plasma membrane of choroid plexus epithelial cells.

SLC4A7 SLC4A10

6.48e-054115214592810
Pubmed

Genetic and clinical predictors of sexual dysfunction in citalopram-treated depressed patients.

GRIA3 GRIK2

6.48e-054115219295509
Pubmed

The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO3- salvage transporter human Na+-HCO3- cotransport isoform 3.

SLC4A7 SLC4A8

6.48e-054115212403779
Pubmed

A carboxy-terminal domain determines the subunit specificity of KCNQ K+ channel assembly.

KCNQ1 KCNQ3

6.48e-054115212524525
Pubmed

Protection of cardiomyocytes from ischemic/hypoxic cell death via Drbp1 and pMe2GlyDH in cardio-specific ARC transgenic mice.

DMGDH ARC

6.48e-054115218782777
Pubmed

Thrombin selectively engages LIM kinase 1 and slingshot-1L phosphatase to regulate NF-κB activation and endothelial cell inflammation.

RELA F2

6.48e-054115224039253
Pubmed

Molecular expression of SLC4-derived Na+-dependent anion transporters in selected human tissues.

SLC4A7 SLC4A8

6.48e-054115217715183
Pubmed

Inhibition of KCNQ1-4 potassium channels expressed in mammalian cells via M1 muscarinic acetylcholine receptors.

KCNQ1 KCNQ3

6.48e-054115210713961
Pubmed

Nuclear diacylglycerol kinase-theta is activated in response to alpha-thrombin.

DGKZ F2

6.48e-054115211309392
Pubmed

Thrombin Induces CCL2 Expression in Human Lung Fibroblasts via p300 Mediated Histone Acetylation and NF-KappaB Activation.

RELA F2

6.48e-054115228407300
Pubmed

Proteasome-dependent autoregulation of Bruton tyrosine kinase (Btk) promoter via NF-kappaB.

RELA BTK

6.48e-054115218292289
Pubmed

Diacylglycerol kinase iota regulates Ras guanyl-releasing protein 3 and inhibits Rap1 signaling.

DGKZ DGKI

6.48e-054115215894621
Pubmed

Essential role of cofilin-1 in regulating thrombin-induced RelA/p65 nuclear translocation and intercellular adhesion molecule 1 (ICAM-1) expression in endothelial cells.

RELA F2

6.48e-054115219483084
Pubmed

Nebulin regulates thin filament length, contractility, and Z-disk structure in vivo.

FLNA NEB

6.48e-054115216902413
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

FLNA MARK3 APEH CHD9 NSUN2 PDCD4 MYOF AHCY MLH1 TNKS1BP1 PCBP2 MVP HCFC1 ADSS1

6.59e-0512471151427684187
Pubmed

Patterned expression of ion channel genes in mouse dorsal raphe nucleus determined with the Allen Mouse Brain Atlas.

GRIA3 GRIK2 KCNQ3

6.78e-0524115322534482
Pubmed

UPF2 is a critical regulator of liver development, function and regeneration.

TMEM183A TMEM183BP C1S

6.78e-0524115320657840
Pubmed

Identification of 14-3-3epsilon substrates from embryonic murine brain.

FLNA AHI1 MARK3 CBR1 MARK4

8.02e-05132115516944949
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

FLNA TMEM183A MARK3 PRDX4 DMAC2 TRIOBP NSUN2 PDCD4 PDXK MYOF LRP4 TNKS1BP1 PCBP2 HCFC1 PCK2

8.25e-0514401151530833792
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

GPRASP1 CACNA1E SLC4A8 TRIOBP GRIA3 DGKZ GRIK2 SIK3 KIAA0319 ARC DGKI RAPGEF2

8.58e-059631151228671696
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

FLNA SLC4A7 PDGFRA SIGMAR1 PRDX4 CDK11A CP ADAMTS5 SIK3 PDXK NRP2 TINAGL1 MRM3 LOXL2 PCK2

8.97e-0514511151530550785
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

CACNA1E MARK3 LANCL1 GRIA3 DGKZ LACTB MARK4 RAPGEF2

9.56e-05430115832581705
Pubmed

NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure.

AHI1 GRIA3 SLC4A10

9.72e-0527115323359859
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

FLNA KIAA0232 GPATCH1 PPP2R3B TRIOBP MRM3 AHCY MLH1 MVP

1.06e-04560115921653829
Pubmed

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels.

GRIA3 GRIK2

1.08e-04511521717158
Pubmed

Bruton's tyrosine kinase separately regulates NFkappaB p65RelA activation and cytokine interleukin (IL)-10/IL-12 production in TLR9-stimulated B Cells.

RELA BTK

1.08e-045115218276597
Pubmed

The contribution of Kv7 channels to pregnant mouse and human myometrial contractility.

KCNQ1 KCNQ3

1.08e-045115220132415
Pubmed

Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases.

SIGMAR1 RYR3

1.08e-045115233060591
Pubmed

Ca2+ entry via TRPC channels is necessary for thrombin-induced NF-kappaB activation in endothelial cells through AMP-activated protein kinase and protein kinase Cdelta.

RELA F2

1.08e-045115218990707
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

FLNA SLC4A7 ANO8 PREB AHCY TMEM131L ROBO1 TNKS1BP1 HCFC1

1.18e-04568115937774976
Pubmed

14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK.

MARK3 SIK3 MARK4

1.34e-0430115316306228
Pubmed

STK11 is required for the normal program of ciliated cell differentiation in airways.

MARK3 SIK3 MARK4

1.48e-0431115331636950
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

FLNA PRDX4 PDXK MYOF BTK PCBP2 HCFC1

1.53e-04344115730333137
Pubmed

Role of individual MARK isoforms in phosphorylation of tau at Ser²⁶² in Alzheimer's disease.

MARK3 MARK4

1.61e-046115223666762
Pubmed

Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.

RYR3 LRP4

1.61e-046115226025922
Pubmed

Novel expression and regulation of voltage-dependent potassium channels in placentas from women with preeclampsia.

KCNQ1 KCNQ3

1.61e-046115221730298
Pubmed

p300 and C/EBPβ-regulated IKKβ expression are involved in thrombin-induced IL-8/CXCL8 expression in human lung epithelial cells.

RELA F2

1.61e-046115228428115
Pubmed

NF-κB-dependent signals control BOB.1/OBF.1 and Oct2 transcriptional activity in B cells.

RELA BTK

1.61e-046115226361887
Pubmed

Early Hearing Loss upon Disruption of Slc4a10 in C57BL/6 Mice.

SLC4A7 SLC4A10

1.61e-046115231001720
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

FLNA SIGMAR1 PRDX4 APEH CP RELA NSUN2 CBR1 COTL1 MYOF AHCY PCBP2 MVP HCFC1

1.73e-0413671151432687490
Pubmed

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

PRDX4 TOM1L1 PPP2R3B LANCL1 LACTB TRMU ITSN2 AHCY PCBP2

1.86e-04604115938803224
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

FLNA PRDX4 GPATCH1 AHCY MLH1 PCBP2 HCFC1

1.92e-04357115737059091
Pubmed

Genome-scale RNAi screen for host factors required for HIV replication.

SLC4A7 RELA ADAMTS5 F2 PCSK6 TMEM131L PCK1

2.06e-04361115718976975
Pubmed

Glutamate receptors in cortical plasticity: molecular and cellular biology.

GRIA3 GRIK2

2.25e-04711529016303
Pubmed

Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking.

GRIA3 ALS2

2.25e-047115217093100
Pubmed

Global/temporal gene expression in diaphragm and hindlimb muscles of dystrophin-deficient (mdx) mice.

RNF149 NEB

2.25e-047115212176734
Pubmed

Regulation of the polarity kinases PAR-1/MARK by 14-3-3 interaction and phosphorylation.

MARK3 SIK3

2.25e-047115216968750
Pubmed

Glutamate receptors: brain function and signal transduction.

GRIA3 GRIK2

2.25e-04711529651535
Pubmed

Nrp2 is sufficient to instruct circuit formation of mitral-cells to mediate odour-induced attractive social responses.

CDHR1 NRP2

2.25e-047115228731029
Pubmed

DeepCAGE Transcriptomics Reveal an Important Role of the Transcription Factor MAFB in the Lymphatic Endothelium.

MRC1 NRP2

2.25e-047115226549461
Pubmed

Genetic mapping of six mouse peroxiredoxin genes and fourteen peroxiredoxin related sequences.

CACNA1E PRDX4 PCK1

2.73e-0438115310501973
Pubmed

Versican processing by a disintegrin-like and metalloproteinase domain with thrombospondin-1 repeats proteinases-5 and -15 facilitates myoblast fusion.

ADAMTS5 PCSK6

3.00e-048115223233679
Pubmed

Activity-dependent and graded BACE1 expression in the olfactory epithelium is mediated by the retinoic acid metabolizing enzyme CYP26B1.

BACE1 NRP2

3.00e-048115224797530
Pubmed

PlexinA1 is a new Slit receptor and mediates axon guidance function of Slit C-terminal fragments.

NRP2 ROBO1

3.00e-048115225485759
Pubmed

International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.

KCNQ1 KCNQ3 KCNH5

3.18e-0440115316382104
Pubmed

EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.

FLNA PRDX4 APEH NSUN2 COTL1 NRP2 MYOF AHCY PCBP2 MVP

3.43e-048031151036517590
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

CACNA1E GRIA3 DGKZ SIK3 ARC RAPGEF2

3.55e-04281115628706196
Pubmed

Bioinformatics and cellular signaling.

FLNA RELA ITPKC BTK AHCY

3.58e-04182115515102471
GeneFamilyX-linked mental retardation|Angiotensin receptors

GRIA3 ZNF81 RAB39B HCFC1

4.94e-0553694103
GeneFamilyEF-hand domain containing

CACNA1E PLCZ1 GNPTAB PPP2R3B RYR3 ITSN2

1.87e-04219696863
GeneFamilyFerlin family

MYOF FER1L5

2.13e-046692828
GeneFamilyPotassium voltage-gated channels

KCNQ1 KCNQ3 KCNH5

4.75e-0440693274
GeneFamilyEF-hand domain containing|Diacylglycerol kinases

DGKZ DGKI

6.33e-04106921178
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF19 ALS2 ITSN2

2.05e-0366693722
CoexpressionJOHNSTONE_PARVB_TARGETS_3_UP

FLNA RNF149 TRIOBP RELA SIK3 PDCD4 MYOF LOXL2 C1S PCBP2 MVP

3.08e-0643311411M2240
CoexpressionNABA_MATRISOME_METASTATIC_COLORECTAL_LIVER_METASTASIS

F2 FNDC1 LOXL2 HCFC1

8.52e-06301144M47990
CoexpressionBRUECKNER_TARGETS_OF_MIRLET7A3_DN

RNF149 COTL1 LACTB NRP2 LOXL2

2.06e-05761145M11825
CoexpressionGSE8835_HEALTHY_VS_CLL_CD8_TCELL_UP

ZMYND11 CHD9 DGKZ COTL1 PDXK MYOF PCBP2

2.80e-052001147M6262
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 SYNM CDHR1 CP PKHD1L1 RYR3 NRP2 PCSK6

1.85e-0817511580801cccec6915aefc135262fc74580280fd51aa5
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 SYNM CDHR1 CP PKHD1L1 RYR3 NRP2 PCSK6

1.85e-08175115809163e7030f76d706eccabdb1d5ec45f8412aa75
ToppCelldroplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH ACSM1 CP F2 AHCY C1S PCK1

1.35e-071511157cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCellP15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MRC1 CP PKHD1L1 COTL1 RYR3 NRP2 PCSK6

3.67e-07175115784d252f3e432231687613299bbea14978bb4b06b
ToppCellP15-Endothelial-lymphatic_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MRC1 CP PKHD1L1 COTL1 RYR3 NRP2 PCSK6

3.67e-071751157a00c6fa9b33640710dd05a3799031147196f0986
ToppCellfacs-Kidney-nan-18m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH ACSM1 CP CBR1 COTL1 PDXK PCK1

3.97e-071771157d4cd54c07f1e51b5485270348fb7195d53465027
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA ADAMTS5 ARSI FNDC1 LOXL2 PCSK6 C1S

5.54e-071861157a7ab70b049742dfe7ee30557031bfac6412edf52
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDGFRA TRIOBP ADAMTS5 FNDC1 LOXL2 PCSK6 C1S

5.95e-071881157aa516273cdde53c8c0295f06830972388f890c97
ToppCellfacs-Skin-nan-18m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA GRIA3 RFTN2 ADAMTS5 NRP2 FNDC1 LOXL2

6.17e-07189115729287525120be2953b76881ba3cfc4379c265e7a
ToppCellfacs-Skin-nan-18m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA GRIA3 RFTN2 ADAMTS5 NRP2 FNDC1 LOXL2

6.17e-0718911577150dad9a92a715487c2d8130fa01b752ea69663
ToppCellfacs-Skin-nan-18m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA GRIA3 RFTN2 ADAMTS5 NRP2 FNDC1 LOXL2

6.17e-0718911576e4c0effd5192fd00052abc048fdb87a74fb6554
ToppCellfacs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 CACNA1E CP PKHD1L1 NRP2 LOXL2 PCSK6

6.62e-07191115748823a97c38263f2c6e58348214f5b62773a6368
ToppCellCOPD-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

CP ARID5A PDCD4 MYOF ITPKC ITSN2 ARC

6.62e-071911157ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA CP ADAMTS5 FNDC1 LOXL2 PCSK6 C1S

6.62e-0719111571efb47743b6834b64cb0f61721ddbe875b1a66ca
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 CACNA1E CP PKHD1L1 NRP2 LOXL2 PCSK6

6.62e-0719111570eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTS5 ARSI PCDH20 MYOF FNDC1 LOXL2 PCSK6

6.86e-07192115730cefa0990ba1f379f350bfbf994a78db145075e
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA CP ADAMTS5 FNDC1 LOXL2 PCSK6 C1S

6.86e-0719211575e6f8206ee0b10cdba79a7c4a05452cb025a5512
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 FLNA GRIA3 ADAMTS5 FNDC1 SUSD5 LRP4

6.86e-071921157992d08092edbc68c47b945deb8708379738c239a
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA ADAMTS5 ARSI FNDC1 LOXL2 PCSK6 C1S

6.86e-071921157beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA CP ADAMTS5 FNDC1 LOXL2 PCSK6 C1S

6.86e-071921157136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCellfacs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA CP ADAMTS5 FNDC1 LOXL2 PCSK6 C1S

7.10e-071931157735a72fac16397edde95e8eefa6f83caeb5ee5df
ToppCellfacs-Heart-RV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA CP ADAMTS5 FNDC1 LOXL2 PCSK6 C1S

7.10e-07193115776f0f8569255d6cdf1e3b8e954cae72e71f87157
ToppCellfacs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA CP ADAMTS5 FNDC1 LOXL2 PCSK6 C1S

7.10e-071931157ff901d2f3d7a511639c1e3b76058896c0d8a8602
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP42 SYNM CP PPP1R15A COTL1 ARID5A ARC

7.61e-071951157f41a68b7c2621594db8d8952e301eeadc96be26f
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ARHGAP42 FLNA PDGFRA GRIA3 ADAMTS5 LRP4 ROBO1

8.72e-07199115738cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ARHGAP42 PDGFRA GRIA3 ADAMTS5 MYOF FNDC1 LRP4

8.72e-0719911576b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

ARHGAP42 FLNA PDGFRA ADAMTS5 MYOF FNDC1 LRP4

9.02e-0720011579d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

ARHGAP42 PDGFRA GRIA3 ADAMTS5 FNDC1 LRP4 ROBO1

9.02e-072001157a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ARHGAP42 FLNA PDGFRA GRIA3 ADAMTS5 FNDC1 LRP4

9.02e-07200115709537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDGFRA ADAMTS5 ARSI FNDC1 LOXL2 ROBO1 C1S

9.02e-0720011573dacd0afe69bc16bb33336ea9ea99a9cd47731d9
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ARHGAP42 FLNA PDGFRA GRIA3 ADAMTS5 FNDC1 LRP4

9.02e-07200115708bf8c00eee6468215edb3611296bfc8784c4d56
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

ARHGAP42 FLNA PDGFRA GRIA3 ADAMTS5 FNDC1 LRP4

9.02e-07200115702cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDGFRA ADAMTS5 ARSI FNDC1 LOXL2 ROBO1 C1S

9.02e-072001157ac8a5d71acd4d401995babd233f0d3738e8ad2a5
ToppCelldroplet-Liver-hepatocytes-3m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACSM1 CP F2 AHCY C1S PCK1

2.30e-06147115600619115b9a1ec2b967c2992043b41974ece63c4
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CP F2 PCDH20 AHCY C1S PCK1

2.69e-061511156e243b6c76e59035f10519a86399b598dd2123f87
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CP F2 PCDH20 AHCY C1S PCK1

2.69e-061511156cdd2ce0969da446616627e3569bbe5a5d9b475bd
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH CP PCDH20 AHCY C1S PCK1

3.02e-061541156a5289000597068ee8d559f89bce7bce31f35dd57
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH CP GRIK2 ADAMTS5 PCSK6 C1S

4.81e-0616711563e3d8f6df2feefafad5b44ba0ebf5b5a0fe4ed58
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMGDH CP GRIK2 ADAMTS5 PCSK6 C1S

4.81e-0616711563ad9f3122dbe96580f640388ef920ea209fc2349
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACSM1 CP F2 PCSK6 C1S PCK1

4.98e-061681156b98af4043dfa5dfa4413e482879fad88de484675
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMGDH GALM RELA ANO8 PCSK6 ROBO1

4.98e-061681156ca94b29c1030484143a77f2df06dad74d2c6136e
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACSM1 CP F2 PCSK6 C1S PCK1

4.98e-061681156073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCelldroplet-Liver-HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACSM1 CP F2 PCSK6 C1S PCK1

5.15e-061691156f195467438c589f87224bde7da720dea072d110c
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA ADAMTS5 ARSI FNDC1 LOXL2 PCSK6

5.15e-061691156bb43abad2c049b7f4d307737347290e01b3339a3
ToppCelldroplet-Liver-HEPATOCYTES-1m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACSM1 CP F2 PCSK6 C1S PCK1

5.15e-0616911567785cab967a33560830c394c918d6ce625103858
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA ADAMTS5 ARSI FNDC1 LOXL2 PCSK6

5.15e-0616911565f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA ADAMTS5 ARSI FNDC1 LOXL2 PCSK6

5.15e-0616911568bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 CACNA1E CP NRP2 PCSK6 RAB39B

6.30e-0617511569d082ba0e350162aa6e71b668be074b12a27c7ab
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 CACNA1E CP NRP2 PCSK6 RAB39B

6.30e-061751156f641f34b52aec5d047430a6f9d026e915da6c11d
ToppCellP28-Endothelial-lymphatic_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MRC1 CP PKHD1L1 COTL1 NRP2 PCSK6

6.72e-0617711566e330aa3c87fd640526b746a9deb3b2250d2518c
ToppCellP28-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MRC1 CP PKHD1L1 COTL1 NRP2 PCSK6

6.72e-061771156e96a7e4544710aaab8bd2800ecff9667880a8bf4
ToppCellfacs-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 CDHR1 CP PKHD1L1 NRP2 PCSK6

7.63e-061811156b0fff0defba9aea6fba36e378b05a59986e2573a
ToppCellfacs-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 CDHR1 CP PKHD1L1 NRP2 PCSK6

7.63e-061811156cc77ac0e223e012767222e45c5dcadc246d1aa7c
ToppCellfacs-Lung-18m-Endothelial-lymphatic_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 CDHR1 CP PKHD1L1 NRP2 PCSK6

7.63e-061811156ecd52f33841f4e9d946a4edad0d58da9b0cc5ffa
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA ADAMTS5 PCDH20 FNDC1 ROBO1 C1S

8.38e-0618411563bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCelldroplet-Kidney-nan-21m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA ADAMTS5 PCDH20 FNDC1 ROBO1 C1S

8.65e-06185115633cc0e9d8b54cb7408b51235f2a70e044ebae04d
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA ADAMTS5 PCDH20 FNDC1 ROBO1 C1S

8.65e-0618511569954fc85b183c1cc45c3c24e3dadc7984ee6f649
ToppCellLPS_only|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SIK3 PPP1R15A COTL1 ARID5A ITPKC MVP

8.65e-061851156a72ccb147ca505880e2da8f6a70b9d570464a691
ToppCelldroplet-Marrow-nan-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A8 SIGMAR1 GNPTAB GRIA3 NSUN2 AHCY

9.19e-061871156f491ec986dd44e2dabdf4a75c3101e3b6c921872
ToppCelldroplet-Marrow-nan-24m-Myeloid-Cd4_positive_Macrophages|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A8 SIGMAR1 GNPTAB GRIA3 NSUN2 AHCY

9.19e-06187115696dc5dc4dbc1b33c2e66666e9027cfbf7972090b
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA ADAMTS5 FNDC1 LOXL2 PCSK6 C1S

9.48e-0618811562cfa41c64eccb28b5e22f0f91bbc921b75713245
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGAP42 FLNA ADAMTS5 RYR3 TINAGL1 FNDC1

9.48e-0618811564d1e5f85342ae550086609d7680e32730b78b5d2
ToppCellfacs-BAT-Fat-18m-Mesenchymal|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP42 PDGFRA CP ADAMTS5 LOXL2 C1S

9.77e-061891156bba28f57a0708515fdd5acd9592dbbe4a4f57116
ToppCellfacs-BAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP42 PDGFRA CP ADAMTS5 LOXL2 C1S

9.77e-061891156cf293b23a4c0e8a0c9f09115b1d53d9b11de72e2
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA ADAMTS5 FNDC1 LOXL2 PCSK6 C1S

9.77e-0618911560a8b827bba1efd885ad6c06929251c741dc3a541
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA ADAMTS5 FNDC1 LOXL2 PCSK6 C1S

9.77e-06189115656f43e00d81cf3cdf0c39f8d7120f5beab72e258
ToppCellfacs-Skin-Anagen|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MARK3 LANCL1 PDCD4 MYOF PCSK6 AHCY

9.77e-061891156adbfc723130079b4caf551f66d2aee86fab1903c
ToppCellfacs-BAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP42 PDGFRA CP ADAMTS5 LOXL2 C1S

9.77e-06189115687323e86a5b5d159920a07e6bd7ef5e3438cd085
ToppCellMesenchymal-airway_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

ARHGAP42 FLNA ADAMTS5 RYR3 TINAGL1 FNDC1

1.01e-051901156645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 CACNA1E CP PKHD1L1 NRP2 PCSK6

1.01e-051901156f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 CACNA1E CP PKHD1L1 NRP2 PCSK6

1.01e-051901156a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 CACNA1E CP PKHD1L1 NRP2 PCSK6

1.01e-05190115657c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCellfacs-Heart-LV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA ADAMTS5 FNDC1 LOXL2 PCSK6 C1S

1.04e-051911156b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHI1 PDGFRA CP CHD9 ADAMTS5 C1S

1.04e-0519111567d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCellLV-02._Fibroblast_II|World / Chamber and Cluster_Paper

ACSM1 CHD9 ADAMTS5 PCSK6 ROBO1 C1S

1.04e-051911156d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA CP ADAMTS5 FNDC1 LOXL2 PCSK6

1.07e-051921156671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGAP42 PDGFRA GRIA3 ADAMTS5 LRP4 ROBO1

1.07e-05192115672881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA CHD9 ADAMTS5 FNDC1 LOXL2 C1S

1.07e-05192115611088878043a6ff95ba1970361256a82e434b80a
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNM CP PPP1R15A COTL1 ARID5A ARC

1.07e-051921156c47df468cf78a90929913c9022e8078a53cdf680
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA SYNM RYR3 NRP2 TINAGL1 MYOF

1.07e-051921156d0fb6885f023d55a2b7984c99db9c6463258f788
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA CP ADAMTS5 FNDC1 LOXL2 PCSK6

1.07e-051921156840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA CP ADAMTS5 FNDC1 LOXL2 C1S

1.10e-051931156d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA ADAMTS5 FNDC1 LOXL2 PCSK6 C1S

1.10e-051931156428b1a3ad87dff7f65de5161d40f102572a9341b
ToppCellILEUM-inflamed-(8)_Smooth_muscle_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PDGFRA ADAMTS5 LOXL2 PCSK6 LRP4 C1S

1.10e-051931156084c88f08ce0ecd6c9f4334caed370eb2154f896
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA ADAMTS5 FNDC1 LOXL2 PCSK6 C1S

1.10e-051931156eff718664fe0aaf89050efd9cc7b6dfb1df46666
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA SYNM RYR3 NRP2 TINAGL1 MYOF

1.10e-0519311560256e8fe4a47f2e2a43ef9d19bfc047d20806d69
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Mesenchymal-mesenchymal_stem_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA ADAMTS5 FNDC1 LOXL2 PCSK6 C1S

1.10e-051931156160691b671710be10220803d788c2c961c236af1
ToppCellfacs-Kidney-nan-18m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA CP ADAMTS5 FNDC1 PCSK6 C1S

1.13e-051941156bbc625b4cc53bb7d6254fde287258e51f9171572
ToppCellfacs-Heart-RA-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALM PDGFRA PRDX4 CP PCSK6 C1S

1.13e-05194115648063c9fe3e12aeff0707acada1baa2f8621f093
ToppCellfacs-Kidney-nan-18m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA CP ADAMTS5 FNDC1 PCSK6 C1S

1.13e-051941156fcd5e9238d299c41f0bf9693b56cd8c900d2112b
ToppCellfacs-Heart-RA-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALM PDGFRA PRDX4 CP PCSK6 C1S

1.13e-0519411564f31d2cf7eb37b45fefc4da5b41aac0bfdd847b3
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA ADAMTS5 PCDH20 FNDC1 PCSK6 C1S

1.13e-0519411560e315c63407fa00643722a7d6138b1502f79b10d
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA ADAMTS5 PCDH20 FNDC1 PCSK6 C1S

1.13e-051941156588c45dafa00547b2506e298a2434b1b5e15560d
ToppCellfacs-Kidney-nan-18m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA CP ADAMTS5 FNDC1 PCSK6 C1S

1.13e-0519411566afc21c5fec30ab8e373e3e46ab7866204c805b6
ToppCelldroplet-Fat-SCAT-30m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFRA ADAMTS5 PCDH20 FNDC1 PCSK6 C1S

1.13e-051941156c2990d6eda3954dc01913bf3910df79f06e0010a
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

PDGFRA ACSM1 ADAMTS5 PCSK6 ROBO1 C1S

1.17e-051951156f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MRC1 FLNA NLRP12 RNF149 COTL1 PDXK

1.20e-0519611567dff78ff7b2b333680de1c9ca78190770574d796
ToppCellControl-Myeloid-TRAM3|Control / Disease group,lineage and cell class (2021.01.30)

PPP1R15A CBR1 PDXK LACTB NRP2 MYOF

1.24e-051971156733ff40039d67e561c2ded7c9bd0b4353101741e
ToppCellBAL-Control-Myeloid-TRAM-TRAM3|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PPP1R15A CBR1 PDXK LACTB NRP2 MYOF

1.24e-0519711564416efdbd9c4ac3356a5dff2d535c2d7383376a9
ToppCellBAL-Control-Myeloid-TRAM-TRAM3-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PPP1R15A CBR1 PDXK LACTB NRP2 MYOF

1.24e-0519711560f1c4a328968b32874e6ebb0803e665adcbbc450
DiseasePhosphoenolpyruvate carboxykinase deficiency

PCK1 PCK2

1.45e-0521132C0268194
Diseaseanemia (implicated_via_orthology)

SLC4A7 SLC4A8 SLC4A10

2.41e-05151133DOID:2355 (implicated_via_orthology)
Diseaseprenylcysteine oxidase-like measurement

NLRP12 C1S

4.35e-0531132EFO_0801910
Diseaseadenylosuccinate synthetase isozyme 2 measurement

NLRP12 ADSS1

4.35e-0531132EFO_0801345
DiseaseJuvenile amyotrophic lateral sclerosis

SIGMAR1 ALS2

4.35e-0531132cv:C3468114
DiseaseAutistic Disorder

ZMYND11 AHI1 CP GRIK2 NRP2 ROBO1 RAB39B

6.80e-052611137C0004352
Diseaseprothrombin measurement

DGKZ F2

8.68e-0541132EFO_0020692
DiseaseJuvenile amyotrophic lateral sclerosis

SIGMAR1 ALS2

8.68e-0541132C3468114
Diseasevisual impairment and progressive phthisis bulbi (implicated_via_orthology)

MARK3 MARK4

8.68e-0541132DOID:0070356 (implicated_via_orthology)
DiseaseHepatolenticular Degeneration

CP LOXL2 AHCY

1.04e-04241133C0019202
DiseaseHepatic Form of Wilson Disease

CP LOXL2 AHCY

1.04e-04241133C1527352
DiseaseSchizophrenia

AHI1 SIGMAR1 ACSM1 BACE1 CP GRIA3 RELA GRIK2 F2 ARC KCNQ3 PCK1

1.49e-0488311312C0036341
DiseasePsychosexual Disorders

GRIA3 GRIK2

2.16e-0461132C0033953
DiseaseHypoactive Sexual Desire Disorder

GRIA3 GRIK2

2.16e-0461132C0020594
DiseaseSexual Arousal Disorder

GRIA3 GRIK2

2.16e-0461132C0036902
DiseaseFrigidity

GRIA3 GRIK2

2.16e-0461132C0016722
DiseaseOrgasmic Disorder

GRIA3 GRIK2

2.16e-0461132C0029261
DiseaseMental Retardation, X-Linked 1

ZNF81 RAB39B HCFC1

2.50e-04321133C2931498
Diseaseepididymis-specific alpha-mannosidase measurement

GNPTAB C1S

3.01e-0471132EFO_0801577
Diseaselysosomal protective protein measurement

GNPTAB TMEM131L

3.01e-0471132EFO_0008215
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

MYOF FER1L5

3.01e-0471132DOID:11724 (implicated_via_orthology)
DiseaseColonic Neoplasms

CP RELA GRIK2 CBR1 MLH1

3.05e-041521135C0009375
DiseaseMalignant tumor of colon

CP RELA GRIK2 CBR1 MLH1

3.75e-041591135C0007102
Diseaseprotein-tyrosine sulfotransferase 2 measurement

NLRP12 SIK3

4.01e-0481132EFO_0801971
Diseaseprostate adenocarcinoma (is_marker_for)

PDGFRA RELA

6.41e-04101132DOID:2526 (is_marker_for)
Diseaselong QT syndrome (implicated_via_orthology)

KCNQ1 KCNQ3

6.41e-04101132DOID:2843 (implicated_via_orthology)
Diseaseglomerulonephritis (is_implicated_in)

F2 CNDP1

7.82e-04111132DOID:2921 (is_implicated_in)
Diseasehyperhomocysteinemia (implicated_via_orthology)

F2 AHCY

7.82e-04111132DOID:9279 (implicated_via_orthology)
DiseaseEpilepsy

FLNA SLC4A10 RAB39B KCNH5

8.33e-041091134C0014544
DiseaseMalignant neoplasm of breast

FLNA RNF149 RELA GRIK2 SIK3 COTL1 PCDH20 PDCD4 LOXL2 BTK ITSN2 ROBO1

8.59e-04107411312C0006142
Diseaseamino acid measurement

GALM DCDC1 GRIK2 RYR3 NRP2 GUCY2C SUSD5 PCSK6 MARK4

1.21e-036781139EFO_0005134
Diseasebrain measurement, neuroimaging measurement

DCDC1 MARK3 GPATCH1 TRIOBP RFTN2 SLC4A10 DGKI ROBO1

1.28e-035501138EFO_0004346, EFO_0004464
Diseasetriglycerides to total lipids in small VLDL percentage

DMGDH SIK3 PCSK6

1.45e-03581133EFO_0022338
DiseaseIntellectual Disability

CACNA1E ZMYND11 AHI1 NSUN2 SLC4A10 RAB39B CNDP1

1.70e-034471137C3714756
Diseaseproprotein convertase subtilisin/kexin type 7 measurement

BACE1 SIK3

1.90e-03171132EFO_0008270
DiseaseCongenital Myasthenic Syndromes, Postsynaptic

AK9 LRP4

1.90e-03171132C0751883
DiseaseAmyotrophic lateral sclerosis

SIGMAR1 ALS2

1.90e-03171132cv:C0002736
Diseaseimmature granulocyte count

NLRP12 MARK4

1.90e-03171132EFO_0803542
DiseaseProfound Mental Retardation

AHI1 SLC4A10 RAB39B CNDP1

2.04e-031391134C0020796
DiseaseMental Retardation, Psychosocial

AHI1 SLC4A10 RAB39B CNDP1

2.04e-031391134C0025363
DiseaseMental deficiency

AHI1 SLC4A10 RAB39B CNDP1

2.04e-031391134C0917816
Diseasevenous thromboembolism, fibrinogen measurement

CHD9 DGKZ LRP4

2.19e-03671133EFO_0004286, EFO_0004623
Diseaseneurodegenerative disease (implicated_via_orthology)

MARK3 GRIA3 GRIK2 MARK4

2.38e-031451134DOID:1289 (implicated_via_orthology)
Diseaselaryngeal squamous cell carcinoma (is_marker_for)

RELA MLH1

2.38e-03191132DOID:2876 (is_marker_for)
Diseasewhite matter lesion progression measurement

CACNA1E SLC4A8 FNDC1

2.59e-03711133EFO_0007746
Diseaserenal system measurement

DCDC1 GRIK2

2.64e-03201132EFO_0004742
Diseaseserum homoarginine measurement

TINAGL1 KCNQ1

2.64e-03201132EFO_0005421
Diseaseserum gamma-glutamyl transferase measurement

DMGDH ARHGEF19 SLC4A8 FSIP1 GPATCH1 TRIOBP CHD9 MLH1 ROBO1 C1S

2.72e-0391411310EFO_0004532
DiseaseRetinal Degeneration

AHI1 CP

2.91e-03211132C0035304
DiseaseLiver Cirrhosis, Experimental

FLNA PDGFRA RELA COTL1 LOXL2 MVP PCK1 PCK2 CNDP1

2.97e-037741139C0023893
Diseaseintellectual disability (implicated_via_orthology)

NSUN2 PREB ITSN2

3.02e-03751133DOID:1059 (implicated_via_orthology)
Diseasemean arterial pressure

ARHGAP42 SLC4A7 DCDC1 DGKZ MARK4 SLC4A10 ROBO1

3.14e-034991137EFO_0006340
Diseaseseminoma (is_marker_for)

PDGFRA KCNQ1

3.19e-03221132DOID:4440 (is_marker_for)
DiseaseHeadache, type 2 diabetes mellitus

PCSK6 KCNQ1

3.49e-03231132HP_0002315, MONDO_0005148
Diseasevenous thromboembolism, tissue plasminogen activator measurement

DGKZ LRP4

3.49e-03231132EFO_0004286, EFO_0004791
Diseasecarnosine measurement

GRIK2 CNDP1

3.80e-03241132EFO_0010470

Protein segments in the cluster

PeptideGeneStartEntry
PYTQGKWEGELGTDL

BACE1

131

P56817
WKNVYDELGGSPGST

ARID5A

111

Q03989
AVDPDTGPWGEVKYS

CDHR1

496

Q96JP9
GYECKDWIGPNDGIT

CACNA1E

276

Q15878
STAGLGYGSWEIDPK

BTK

386

Q06187
GSEDGIVYVWNPETG

AHI1

861

Q8N157
LTEDGEVYSFGTLPW

ALS2

56

Q96Q42
DGLDGYDVWPAISEG

ARSI

366

Q5FYB1
VGEWKLLTGDPGYGD

ARSI

421

Q5FYB1
GPWAEEEKGRVYGDG

ADAMTS5

171

Q9UNA0
WADRLESTGGKYPVG

ARC

126

Q7LC44
EWSYPEGGVKVLITG

CAMTA2

541

O94983
VVGVDWAEGLKSGPE

DMAC2

231

Q9NW81
DWGDTLTYEIGPRKS

FAM186B

106

Q8IYM0
GAELAYKWGTLDSPG

ANO8

306

Q9HCE9
YKWGTLDSPGEAVEE

ANO8

311

Q9HCE9
TIQEGWEGVKSGFVP

RAB39B

181

Q96DA2
DGDSGGPELSDWEKY

PPP2R3B

491

Q9Y5P8
GGVYWEGIDEPLASG

PCK1

366

P35558
WTVIEGCEIKTDYGP

RFTN2

346

Q52LD8
EGYDGPVTLDDWGDV

GUCY2C

361

P25092
VDEKTVGEPGWLYGS

ITSN2

786

Q9NZM3
EPSADGSWKELYTDG

ITPKC

216

Q96DU7
EAGWEGGYPEIVKEN

NSUN2

31

Q08J23
GEKGWVPQAYVEEIS

ARHGEF19

761

Q8IW93
TYVWKIPERSGAGTE

CP

856

P00450
EVVDLQWTYPGEVKG

PDGFRA

241

P16234
GSGVVAWDIPITYGV

HCFC1

181

P51610
SSYTLWVEAVDGGEP

PCDH20

706

Q8N6Y1
GRPEDGTYAWGKTIS

DCDC1

1676

M0R2J8
TTIGYGDKVPQTWVG

KCNQ1

311

P51787
LKSADPRDGTGYTGW

LANCL1

51

O43813
TVWRGYLTTDKEVPG

GNPTAB

206

Q3T906
GGLREPWYVVEKDSV

TRMU

271

O75648
PGKGLEWIGEIYHSG

IGHV4-4

61

A0A075B6R2
ISWTGRKIDPVGVDY

KIAA1109

4936

Q2LD37
TIGYGDKTPKTWEGR

KCNQ3

316

O43525
VSVDGKEVWSEGLGY

LACTB

131

P83111
AGIWEGGPSKDSLYV

KCNH5

406

Q8NCM2
SSSYGKGEGPIWLDN

LOXL2

111

Q9Y4K0
LKDEEPGDGLYGWTA

GPATCH1

311

Q9BRR8
GDGKYGARDPETKIW

GRIA3

476

P42263
IYSASWGPDDDGKTV

PCSK6

301

P29122
TSDGGVYWEGIDQPL

PCK2

381

Q16822
KGVWGTPGQVYDVEE

PDCD4

121

Q53EL6
VDGGDYTTPSKPWDV

KIAA0232

906

Q92628
PDEGFEGKSLYESWT

FOLH1B

176

Q9HBA9
GGEWKHGRIILPSYD

NRP2

751

O60462
KVVAGDEWLFEGPGT

MVP

136

Q14764
SGIESSSPEVKGYWG

PCBP2

266

Q15366
PGELKVWVTYTLDGG

GALM

141

Q96C23
SEYGVAPEWGDVVKQ

CHD9

2591

Q3L8U1
WVTFKYDGSTIVPGE

COTL1

26

Q14019
LNWGGGYTDEPVSKI

DGKI

471

O75912
YTLVVKWGDEHIPGS

FLNA

2626

P21333
VDWDKATPGDVVTGY

FNDC1

1676

Q4ZHG4
VEKSWDIEVPEGYGI

C1S

36

P09871
ELGTPSEKIWPGYSE

CDK11A

641

Q9UQ88
KEGWPSSAYGVTKIG

CBR1

186

P16152
GVGKYLSDWILHGEP

DMGDH

406

Q9UI17
GKKYDGPEVDVWSLG

MARK3

226

P27448
KYDGPEVDIWSLGVI

MARK4

231

Q96L34
SEGDQSGWVVPVKGY

FSIP1

296

Q8NA03
NWGGGYTDEPVSKIL

DGKZ

391

Q13574
EEGLEKIGTWDPASG

GRIK2

396

Q13002
GIPVYAWKGETDEEY

AHCY

96

P23526
GWGYRPGKETEEEEA

PPP1R15A

481

O75807
DGSKVDYVSWATGEP

MRC1

876

P22897
YPAGGGSWKSRPEEE

GPRASP1

686

Q5JY77
SSFGYWDPVKLSEGE

AK9

1346

Q5TCS8
LDGYPVTEGAWRKTE

SUSD5

371

O60279
SVKITGWGEETLPDG

TINAGL1

401

Q9GZM7
GWGEETLPDGRTLKY

TINAGL1

406

Q9GZM7
DVEDGGDRWSKPYVA

SLC4A7

141

Q9Y6M7
WSQGFPGGVDVSEVK

TOM1L1

126

O75674
VEYETLPGWKADTTG

ADSS1

401

Q8N142
PYWEGTAVIDGEFKE

PRDX4

86

Q13162
GVEEDKGLYSPGDLW

TMEM131L

1396

A2VDJ0
VSPGPWGLVKEEEGY

SYNM

776

O15061
WGLVKEEEGYGESDV

SYNM

781

O15061
VDSKGWEYGVGIPPS

FER1L5

911

A0AVI2
WTEAPAAVVIGGETY

MRM3

346

Q9HC36
EPGWLKATYEGKTGL

ARHGAP42

851

A6NI28
GPSDLWGYVSALVKG

PLCZ1

181

Q86YW0
DGAGGEEYPMDIWLL

TMEM183BP

126

Q1AE95
WREGTTKSEVFYPGE

SIGMAR1

136

Q99720
GKEYDGPKVDIWSLG

SIK3

236

Q9Y2K2
VEDGGERWSKPYVAT

SLC4A8

146

Q2Y0W8
GWTEEDGPKEGLAEY

MLH1

596

P40692
LGDKWDGEGSMYVPE

PDXK

116

O00764
KAPEGAWGGTSREYK

TRIOBP

1471

Q9H2D6
GTGPGEEKQFLEVWE

APEH

111

P13798
YTGGEVVLPKDQEEW

ACSM1

341

Q08AH1
GDGWLTDPYVLTEVD

CNDP1

141

Q96KN2
GYWGEDSEGDTGTIK

RAPGEF2

1331

Q9Y4G8
TGGTDGYVRVWKVPS

PREB

171

Q9HCU5
LDVIKALGYWGEPGD

RNF149

311

Q8NC42
WDYGYEAGTVPEKEI

SETDB2

691

Q96T68
GPQLEGEKDWGLEGY

ZSWIM9

561

Q86XI8
ATGVPWGYEETKTLL

ZSCAN32

251

Q9NX65
GFPWGEAGIKEEPSL

ZFHX2

141

Q9C0A1
DGAGGEEYPMDIWLL

TMEM183A

126

Q8IXX5
PSGWGSYGLAVEEEL

RYR3

2521

Q15413
DVEDGGERWSKPYVA

SLC4A10

146

Q6U841
DPGLGERDWTSKYGQ

TNKS1BP1

766

Q9C0C2
DIDGLEVVGKGWPFS

MYCBPAP

351

Q8TBZ2
TPTIEWYKGGERVET

ROBO1

96

Q9Y6N7
IKIVGEDYPGWSEDS

PKHD1L1

3261

Q86WI1
SKAGIEQEGYWLPGD

ZMYND11

76

Q15326
KWLEDVTPGYSTQEG

ZGRF1

1386

Q86YA3
DGDEEGVWCYVAGKP

F2

266

P00734
AGSKAIVWDEYLTGP

VPS33A

31

Q96AX1
GNWGEDYSKGVSPLE

TGM7

241

Q96PF1
KEDIEVYFTGPGWEA

RELA

221

Q04206
FKLEQGEGPWTLEGE

ZNF81

71

P51508
LYEWSLGPGSEGKHV

KIAA0319

561

Q5VV43
IGVDPQEGKVYWSDS

LRP4

1086

O75096
YLGTATELGEGKIPW

NLRP12

31

P59046
RAVDEKGWEYGITIP

MYOF

986

Q9NZM1
YKGLGWSPAGSLEVE

NEB

2176

P20929