Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H3K9me2/H3K9me3 demethylase activity	KDM4D KDM4C KDM4E KDM4B	1.53e-09	6	65	4	GO:0140684
GeneOntologyMolecularFunction	histone H3 demethylase activity	KDM4D KDM5B KDM4C KDM4E KDM4B	2.90e-08	28	65	5	GO:0141052
GeneOntologyMolecularFunction	histone demethylase activity	KDM4D KDM5B KDM4C KDM4E KDM4B	4.97e-08	31	65	5	GO:0032452
GeneOntologyMolecularFunction	protein demethylase activity	KDM4D KDM5B KDM4C KDM4E KDM4B	5.88e-08	32	65	5	GO:0140457
GeneOntologyMolecularFunction	histone H3K9 demethylase activity	KDM4D KDM4C KDM4E KDM4B	9.99e-08	14	65	4	GO:0032454
GeneOntologyMolecularFunction	demethylase activity	KDM4D KDM5B KDM4C KDM4E KDM4B	3.08e-07	44	65	5	GO:0032451
GeneOntologyMolecularFunction	2-oxoglutarate-dependent dioxygenase activity	KDM4D KDM5B KDM4C KDM4E KDM4B	2.22e-06	65	65	5	GO:0016706
GeneOntologyMolecularFunction	dioxygenase activity	KDM4D KDM5B KDM4C KDM4E KDM4B	1.68e-05	98	65	5	GO:0051213
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	KDM4D KDM5B KDM4C KDM4E FADS2B KDM4B	3.99e-05	194	65	6	GO:0016705
GeneOntologyMolecularFunction	histone H3K36 demethylase activity	KDM4C KDM4B	5.63e-04	11	65	2	GO:0051864
GeneOntologyMolecularFunction	histone modifying activity	KDM4D KDM5B KDM4C KDM4E KDM4B	8.96e-04	229	65	5	GO:0140993
GeneOntologyCellularComponent	pericentric heterochromatin	KDM4D KDM4C KDM4E KDM4B	2.87e-06	32	65	4	GO:0005721
GeneOntologyCellularComponent	heterochromatin	KDM4D KDM4C KDM4E KDM4B	2.77e-04	101	65	4	GO:0000792
Domain	JmjN	KDM4D KDM5B KDM4C KDM4E KDM4B	7.82e-11	10	61	5	SM00545
Domain	JMJN	KDM4D KDM5B KDM4C KDM4E KDM4B	7.82e-11	10	61	5	PS51183
Domain	JmjN	KDM4D KDM5B KDM4C KDM4E KDM4B	7.82e-11	10	61	5	PF02375
Domain	JmjN	KDM4D KDM5B KDM4C KDM4E KDM4B	7.82e-11	10	61	5	IPR003349
Domain	JmjC	KDM4D KDM5B KDM4C KDM4E KDM4B	1.27e-08	24	61	5	PF02373
Domain	JMJC	KDM4D KDM5B KDM4C KDM4E KDM4B	5.92e-08	32	61	5	PS51184
Domain	JmjC_dom	KDM4D KDM5B KDM4C KDM4E KDM4B	5.92e-08	32	61	5	IPR003347
Domain	JmjC	KDM4D KDM5B KDM4C KDM4E KDM4B	6.95e-08	33	61	5	SM00558
Domain	FG-GAP	BBS2 CRTAC1 ITGA7	6.39e-05	24	61	3	PF01839
Domain	FG-GAP	BBS2 CRTAC1 ITGA7	6.39e-05	24	61	3	IPR013517
Domain	EPHD	KDM4C KDM4B	2.32e-03	22	61	2	PS51805
Domain	FG_GAP	CRTAC1 ITGA7	2.32e-03	22	61	2	PS51470
Domain	TUDOR	KDM4C KDM4B	2.54e-03	23	61	2	PS50304
Domain	PHD	KDM5B KDM4C KDM4B	3.08e-03	89	61	3	SM00249
Domain	Znf_PHD	KDM5B KDM4C KDM4B	3.28e-03	91	61	3	IPR001965
Domain	TUDOR	KDM4C KDM4B	3.49e-03	27	61	2	SM00333
Domain	ZF_PHD_2	KDM5B KDM4C KDM4B	3.71e-03	95	61	3	PS50016
Domain	ZF_PHD_1	KDM5B KDM4C KDM4B	3.82e-03	96	61	3	PS01359
Domain	ArfGap	ARFGAP2 AGFG1	4.02e-03	29	61	2	SM00105
Domain	ArfGap	ARFGAP2 AGFG1	4.02e-03	29	61	2	PF01412
Domain	ARFGAP	ARFGAP2 AGFG1	4.02e-03	29	61	2	PS50115
Domain	ArfGAP	ARFGAP2 AGFG1	4.02e-03	29	61	2	IPR001164
Domain	Tudor	KDM4C KDM4B	4.30e-03	30	61	2	IPR002999
Domain	PSI	PLXDC2 PLXNC1	4.89e-03	32	61	2	PF01437
Domain	Plexin_repeat	PLXDC2 PLXNC1	4.89e-03	32	61	2	IPR002165
Domain	Cadherin_CS	DCHS2 CDHR1 PCDH9	5.44e-03	109	61	3	IPR020894
Domain	CADHERIN_1	DCHS2 CDHR1 PCDH9	6.02e-03	113	61	3	PS00232
Domain	Cadherin	DCHS2 CDHR1 PCDH9	6.02e-03	113	61	3	PF00028
Domain	CADHERIN_2	DCHS2 CDHR1 PCDH9	6.16e-03	114	61	3	PS50268
Domain	-	DCHS2 CDHR1 PCDH9	6.16e-03	114	61	3	2.60.40.60
Domain	CA	DCHS2 CDHR1 PCDH9	6.31e-03	115	61	3	SM00112
Domain	Cadherin-like	DCHS2 CDHR1 PCDH9	6.47e-03	116	61	3	IPR015919
Domain	Cadherin	DCHS2 CDHR1 PCDH9	6.78e-03	118	61	3	IPR002126
Domain	C-type_lectin_CS	SELP PRG3	8.69e-03	43	61	2	IPR018378
Domain	PSI	PLXDC2 PLXNC1	9.09e-03	44	61	2	IPR016201
Domain	Olfact_rcpt	OR51A4 OR5D18 OR10J1 OR52B2 OR6K6	9.12e-03	393	61	5	IPR000725
Domain	PSI	PLXDC2 PLXNC1	9.90e-03	46	61	2	SM00423
Pathway	REACTOME_HDMS_DEMETHYLATE_HISTONES	KDM4D KDM5B KDM4C KDM4E KDM4B	2.96e-08	29	45	5	MM14934
Pathway	REACTOME_HDMS_DEMETHYLATE_HISTONES	KDM4D KDM5B KDM4C KDM4B	1.87e-05	50	45	4	M27232
Pubmed	Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells.	KDM4D KDM4C KDM4E KDM4B	5.55e-11	5	65	4	16738407
Pubmed	Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family.	KDM4D KDM4C KDM4E KDM4B	5.55e-11	5	65	4	21914792
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KDM4D KDM5B KDM4C KDM4E KDM4B	3.87e-10	21	65	5	27626377
Pubmed	Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins.	KDM4D KDM4C KDM4E KDM4B	3.63e-09	11	65	4	19144645
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	KDM4D KDM5B KDM4C KDM4E KDM4B	3.49e-08	49	65	5	34368113
Pubmed	New nomenclature for chromatin-modifying enzymes.	KDM4D KDM5B KDM4C KDM4E KDM4B	7.57e-08	57	65	5	18022353
Pubmed	Identification and characterization of JMJD2 family genes in silico.	KDM4D KDM4C KDM4B	1.24e-07	6	65	3	15138608
Pubmed	Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.	KDM5B KDM4C KDM4B	2.17e-07	7	65	3	28262558
Pubmed	Differential regulation and impact of fucosyltransferase VII and core 2 β1,6-N-acetyl-glycosaminyltransferase for generation of E-selectin and P-selectin ligands in murine CD4+ T cells.	SELP TBX21 IL7	3.47e-07	8	65	3	23039181
Pubmed	Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.	KDM4D KDM4C KDM4B	2.23e-06	14	65	3	16603238
Pubmed	Histone Demethylase JMJD2D Interacts With β-Catenin to Induce Transcription and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice.	KDM4D KDM4E	3.44e-06	2	65	2	30472235
Pubmed	Repressive histone methylation regulates cardiac myocyte cell cycle exit.	KDM4D KDM4E	3.44e-06	2	65	2	29800554
Pubmed	The development of airway hyperreactivity in T-bet-deficient mice requires CD1d-restricted NKT cells.	CD1D TBX21	3.44e-06	2	65	2	19234223
Pubmed	Strong KDM4B and KDM4D Expression Associates with Radioresistance and Aggressive Phenotype in Classical Hodgkin Lymphoma.	KDM4D KDM4B	3.44e-06	2	65	2	27630312
Pubmed	Demethylase JMJD2D induces PD-L1 expression to promote colorectal cancer immune escape by enhancing IFNGR1-STAT3-IRF1 signaling.	KDM4D KDM4E	3.44e-06	2	65	2	35027670
Pubmed	Embryonic development following somatic cell nuclear transfer impeded by persisting histone methylation.	KDM4D KDM4E	3.44e-06	2	65	2	25417163
Pubmed	Kdm4d mutant mice show impaired sperm motility and subfertility.	KDM4D KDM4E	3.44e-06	2	65	2	39034148
Pubmed	Inflammation-induced JMJD2D promotes colitis recovery and colon tumorigenesis by activating Hedgehog signaling.	KDM4D KDM4E	3.44e-06	2	65	2	32094404
Pubmed	Distinct and combinatorial functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in mouse embryonic stem cell identity.	KDM4C KDM4B	3.44e-06	2	65	2	24361252
Pubmed	Tissue-Resident NK Cells Mediate Ischemic Kidney Injury and Are Not Depleted by Anti-Asialo-GM1 Antibody.	CD1D TBX21	1.03e-05	3	65	2	26453755
Pubmed	Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development.	KDM4C KDM4B	1.03e-05	3	65	2	27266524
Pubmed	The histone demethylase JMJD2C is stage-specifically expressed in preimplantation mouse embryos and is required for embryonic development.	KDM4C KDM4B	1.03e-05	3	65	2	19696013
Pubmed	Histone demethylase JMJD2D protects against enteric bacterial infection via up-regulating colonic IL-17F to induce β-defensin expression.	KDM4D KDM4E	1.03e-05	3	65	2	38905308
Pubmed	The testis-enriched histone demethylase, KDM4D, regulates methylation of histone H3 lysine 9 during spermatogenesis in the mouse but is dispensable for fertility.	KDM4D KDM4E	1.03e-05	3	65	2	21293030
Pubmed	Diversity within the JMJD2 histone demethylase family.	KDM4D KDM4C	1.03e-05	3	65	2	17207460
Pubmed	Comparative integromics on JMJD2A, JMJD2B and JMJD2C: preferential expression of JMJD2C in undifferentiated ES cells.	KDM4C KDM4B	1.03e-05	3	65	2	17611647
Pubmed	The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice.	KDM4D KDM4E	1.03e-05	3	65	2	21555854
Pubmed	The KDM4/JMJD2 histone demethylases are required for hematopoietic stem cell maintenance.	KDM4C KDM4B	1.03e-05	3	65	2	31434704
Pubmed	Histone demethylase JMJD2B and JMJD2C induce fibroblast growth factor 2: mediated tumorigenesis of osteosarcoma.	KDM4C KDM4B	1.03e-05	3	65	2	25636512
Pubmed	TRIM14 inhibits OPTN-mediated autophagic degradation of KDM4D to epigenetically regulate inflammation.	KDM4D KDM4E	2.06e-05	4	65	2	35145029
Pubmed	The histone demethylase Kdm4 suppresses activation of hepatic stellate cell by inducing MiR-29 transcription.	KDM4C KDM4B	2.06e-05	4	65	2	31014673
Pubmed	Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells.	CD1D TBX21	2.06e-05	4	65	2	24097110
Pubmed	IL-15 regulates homeostasis and terminal maturation of NKT cells.	CD1D IL7	2.06e-05	4	65	2	22084435
Pubmed	Histone demethylase KDM4D cooperates with NFIB and MLL1 complex to regulate adipogenic differentiation of C3H10T1/2 mesenchymal stem cells.	KDM4D KDM4E	2.06e-05	4	65	2	32080306
Pubmed	Isolation and characterization of rat skeletal muscle and cytoplasmic actin genes.	KDM4D KDM4E	2.06e-05	4	65	2	6953429
Pubmed	Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha.	KDM4C KDM4B	2.06e-05	4	65	2	18713068
Pubmed	Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells.	KDM4C KDM4B	2.06e-05	4	65	2	27257215
Pubmed	Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.	NF1 SLC20A1 SLC35E1 MACF1 TNFAIP8 PCDH9 GPR107	2.68e-05	467	65	7	30194290
Pubmed	Homeostasis of V alpha 14i NKT cells.	CD1D IL7	3.43e-05	5	65	2	12244311
Pubmed	Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development.	KDM4C KDM4B	7.18e-05	7	65	2	21445275
Pubmed	Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.	CLN8 PIK3CB CDHR1 BBS2 MACF1	7.70e-05	233	65	5	32290105
Pubmed	Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.	KDM5B KDM4C KDM4B	7.81e-05	44	65	3	24183668
Pubmed	Cloning and expression analysis of murine phospholipase D1.	NF1 IL7	9.56e-05	8	65	2	9307024
Pubmed	PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair.	KDM4D KDM4E	1.53e-04	10	65	2	24550317
Pubmed	Deletion of JMJD2B in neurons leads to defective spine maturation, hyperactive behavior and memory deficits in mouse.	KDM4C KDM4B	1.53e-04	10	65	2	27023172
Pubmed	The intracellular NADH level regulates atrophic nonunion pathogenesis through the CtBP2-p300-Runx2 transcriptional complex.	PLXDC2 TNFAIP8 DDB1 GPR107	1.57e-04	144	65	4	30585266
Pubmed	Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis.	KDM5B KDM4B	2.65e-04	13	65	2	21502505
Pubmed	Tag1 deficiency results in olfactory dysfunction through impaired migration of mitral cells.	OR5D18 TBX21	2.65e-04	13	65	2	26525675
Pubmed	Defining brain wiring patterns and mechanisms through gene trapping in mice.	LRIG3 PLXDC2	3.08e-04	14	65	2	11242070
Pubmed	Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly.	ARFGAP2 AGFG1	3.08e-04	14	65	2	16903783
Pubmed	Tbr2 deficiency in mitral and tufted cells disrupts excitatory-inhibitory balance of neural circuitry in the mouse olfactory bulb.	CDHR1 TBX21	4.06e-04	16	65	2	22745484
Pubmed	Impacts of humanized mouse models on the investigation of HIV-1 infection: illuminating the roles of viral accessory proteins in vivo.	CD1D DDB1	4.06e-04	16	65	2	25807049
Pubmed	Identification of RanBP 9/10 as interacting partners for protein kinase C (PKC) gamma/delta and the D1 dopamine receptor: regulation of PKC-mediated receptor phosphorylation.	MACF1 TRIM5	4.59e-04	17	65	2	20395553
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	KDM4D NF1 KDM4C PIK3CB WFIKKN2 KDM4E PTH2R KDM4B GPR107	4.86e-04	1242	65	9	30973865
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	GLMP LRIG3 PRG3 PLXDC2 WFIKKN2 ATP13A5 ITGA7 MFSD13A	4.87e-04	985	65	8	12975309
Pubmed	TRIM67 Implicates in Regulating the Homeostasis and Synaptic Development of Mitral Cells in the Olfactory Bulb.	PLXNC1 TBX21	5.76e-04	19	65	2	37686246
Pubmed	Identification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouse.	NF1 KDM4C	7.06e-04	21	65	2	25340873
Pubmed	Zfp296 negatively regulates H3K9 methylation in embryonic development as a component of heterochromatin.	KDM4C KDM4B	7.76e-04	22	65	2	28963472
Pubmed	Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.	PRG3 NF1 SLC20A1 IL7	9.35e-04	231	65	4	21048031
Pubmed	Bcl11b/Ctip2 controls the differentiation of vomeronasal sensory neurons in mice.	CDHR1 TBX21	1.09e-03	26	65	2	21752992
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	KDM4C TBX21 TOX3 ZNF407 DDB1 TRIM5 KDM4B	1.24e-03	877	65	7	20211142
Pubmed	Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.	PLXDC2 SCRN1 TNFAIP8 DDB1	1.38e-03	257	65	4	30945288
Pubmed	Identification of proteins that interact with alpha A-crystallin using a human proteome microarray.	SLC20A1 CRTAC1 MYO5C	1.43e-03	118	65	3	24453475
Pubmed	DCAF4L2 promotes colorectal cancer invasion and metastasis via mediating degradation of NFκb negative regulator PPM1B.	DDB1 CLUH	1.65e-03	32	65	2	27158335
Pubmed	Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.	KDM5B KDM4C	1.75e-03	33	65	2	26864203
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM4D KDM5B KDM4C KDM4E KDM4B	3.49e-09	24	46	5	485
GeneFamily	Cadherin related	DCHS2 CDHR1	8.41e-04	17	46	2	24
GeneFamily	ArfGAPs	ARFGAP2 AGFG1	3.18e-03	33	46	2	395
GeneFamily	Tudor domain containing	KDM4C KDM4B	3.99e-03	37	46	2	780
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SELP PRG3	4.88e-03	41	46	2	1298
Disease	medulloblastoma (is_marker_for)	KDM4C KDM4B	4.19e-05	5	61	2	DOID:0050902 (is_marker_for)
Disease	cadherin-7 measurement	SELP PLXDC2	4.19e-05	5	61	2	EFO_0801438
Disease	torsin-1A-interacting protein 1 measurement	SELP PLXDC2	6.27e-05	6	61	2	EFO_0802137
Disease	solute carrier family 22 member 16 measurement	SELP PLXDC2	6.27e-05	6	61	2	EFO_0802079
Disease	total cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement	NF1 CRTAC1 ADCY5	1.45e-04	49	61	3	EFO_0004530, EFO_0004574, EFO_0004611, EFO_0004612
Disease	alopecia areata (is_marker_for)	KDM4C KDM4B	1.87e-04	10	61	2	DOID:986 (is_marker_for)
Disease	prostate cancer (is_marker_for)	KDM5B KDM4C PIK3CB KDM4B	3.10e-04	156	61	4	DOID:10283 (is_marker_for)
Disease	T-cell surface glycoprotein CD3 epsilon chain measurement	SELP PLXDC2	3.23e-04	13	61	2	EFO_0802114
Disease	lipid metabolism disorder (implicated_via_orthology)	FITM1 FADS2B	4.34e-04	15	61	2	DOID:3146 (implicated_via_orthology)
Disease	alcohol use disorder (implicated_via_orthology)	KDM5B KDM4C PIK3CB FADS2B	7.19e-04	195	61	4	DOID:1574 (implicated_via_orthology)
Disease	coagulation factor V measurement	SELP PLXDC2	7.80e-04	20	61	2	EFO_0008087
Disease	partial thromboplastin time	SELP PLXDC2	1.13e-03	24	61	2	EFO_0004310
Disease	Cerebral Astrocytoma	NF1 ACVR1	1.22e-03	25	61	2	C0750935
Disease	Intracranial Astrocytoma	NF1 ACVR1	1.22e-03	25	61	2	C0750936
Disease	Pilocytic Astrocytoma	NF1 ACVR1	1.22e-03	25	61	2	C0334583
Disease	Astrocytoma	NF1 ACVR1	1.22e-03	25	61	2	C0004114
Disease	Juvenile Pilocytic Astrocytoma	NF1 ACVR1	1.22e-03	25	61	2	C0280783
Disease	Diffuse Astrocytoma	NF1 ACVR1	1.22e-03	25	61	2	C0280785
Disease	Grade I Astrocytoma	NF1 ACVR1	1.22e-03	25	61	2	C1704230
Disease	Subependymal Giant Cell Astrocytoma	NF1 ACVR1	1.22e-03	25	61	2	C0205768
Disease	Mixed oligoastrocytoma	NF1 ACVR1	1.22e-03	25	61	2	C0547065
Disease	Childhood Cerebral Astrocytoma	NF1 ACVR1	1.22e-03	25	61	2	C0338070
Disease	Retinitis Pigmentosa	CDHR1 BBS2 AGBL5	1.32e-03	104	61	3	C0035334
Disease	Gemistocytic astrocytoma	NF1 ACVR1	1.32e-03	26	61	2	C0334581
Disease	Protoplasmic astrocytoma	NF1 ACVR1	1.32e-03	26	61	2	C0334580
Disease	Fibrillary Astrocytoma	NF1 ACVR1	1.32e-03	26	61	2	C0334582
Disease	Anaplastic astrocytoma	NF1 ACVR1	1.43e-03	27	61	2	C0334579
Disease	diverticular disease	NF1 SLC6A17 WFIKKN2 TBX21	1.46e-03	236	61	4	EFO_0009959
Disease	glucose metabolism disease (implicated_via_orthology)	HK3 PIK3CB	1.53e-03	28	61	2	DOID:4194 (implicated_via_orthology)
Disease	melanoma	NF1 KDM4C ACVR1 KDM4B	1.75e-03	248	61	4	C0025202
Disease	Unipolar Depression	SELP TBX21 GRIK4 ADCY5	2.04e-03	259	61	4	C0041696

Protein segments in the cluster

Peptide	Gene	Start	Entry
SLNSAHFDFQGCNFS	AGBL5	466	Q8NDL9
DNCFQEAHSFASGQA	ATP13A5	506	Q4VNC0
LCLAQANFAPHFFDN	CDHR1	16	Q96JP9
TTSGHVQFDNCNFEN	FBXO10	196	Q9UK96
QQCFSSLSINDGFHV	ACVR1	51	Q04771
ANATAFFRQHGCTAN	ARFGAP2	86	Q8N6H7
FFRQHGCTANDANTK	ARFGAP2	91	Q8N6H7
AIDFFNNGTSQCPEH	ADCY5	966	O95622
SVHNNGGAVSFQFFF	GPR107	196	Q5VW38
GFNTINHFFCEFSSL	OR5D18	171	Q8NGL1
ENNFQSFVNASCAHP	LRIG3	461	Q6UXM1
AHAEFENFFLQAAAQ	KIAA1755	881	Q5JYT7
LFHGENGQLNCSFEN	PLXNC1	881	O60486
AHNIAFDACVTQGFF	OR52B2	91	Q96RD2
NDNSPKFTHNHFQFF	PCDH9	566	Q9HC56
NHGFNCAESTNFATL	KDM4B	281	O94953
FNHGFNCAESTNFAT	KDM4C	281	Q9H3R0
AGFNHGFNCAEAINF	KDM4D	281	Q6B0I6
NHGFNCAEAINFATP	KDM4E	281	B2RXH2
NLSGDCQDFRFQQHS	MACF1	211	O94854
NQGFNFAEAVNFCTV	KDM5B	591	Q9UGL1
SNACFAQEFFIHGFS	OR51A4	96	Q8NGJ6
SLQNLAAFADTFHCA	MMEL1	751	Q495T6
GQQLFDFAAHCLSEF	HK3	136	P52790
SGNSQNNFHVETKFF	DCHS2	2591	Q6V1P9
NTESFFNDFTGHLNF	FADS2B	406	A8MWK0
CYGGNLVSIHDFNFN	PRG3	131	Q9Y2Y8
NCALQGFNHEGSDLF	BBS2	141	Q9BXC9
NASNNFFHVAFQGKD	CD1D	126	P15813
ASHGNFFNIKFVNSA	FITM1	81	A5D6W6
GSNCLNNEFNFFKRH	IL7	56	P13232
AFFGSQNNFCAFNLT	GLMP	321	Q8WWB7
PLGNFSFNSQCSFHC	SELP	216	P16109
FTFFAVSHFPNQNDN	MARCHF10	601	Q8NA82
IFCDNENGPNFLFHN	CRTAC1	256	Q9NQ79
HEQFGFCQQGTAAAF	ITGA7	191	Q13683
LNQHNRVFFDSCDGF	ENGASE	286	Q8NFI3
LGFSIFNQSHAFFQE	GRIK4	266	Q16099
FNQSHAFFQEFAQSL	GRIK4	271	Q16099
QFLQILTACFGSFAH	SLC20A1	516	Q8WUM9
QVFHCHFNSNFFPLF	MFSD13A	276	Q14CX5
FVDDQQTFFCGNVAH	DDB1	451	Q16531
TDFVFQGFSSFHEQQ	OR10J1	21	P30954
FCGSNQIHQIFCDFT	OR6K6	196	Q8NGW6
QGHCTLGSYADAFQF	RTL5	246	Q5HYW3
HEVFFSGLFENCFNA	TMEM225B	46	P0DP42
LLCHFFTDQFQFADG	PLXDC2	16	Q6UX71
NVFGVCHIFASFNDT	RPS14	26	P62263
VHFENCQDVFSFQVS	PIK3CB	201	P42338
AVSGFCNFAQNVIAF	SLC35E1	266	Q96K37
NNVFDHFSDCEFLAA	TNFAIP8	156	O95379
GNYFEDANSCHSFQS	SCRN1	141	Q12765
FANFAHFNSHAAQNS	AGFG1	221	P52594
ASVNANFAHFDNFPK	AGFG1	276	P52594
TGFFCFENVAVHLSN	CLN8	111	Q9UBY8
SDAFHFFQSGQAKVQ	CLUH	976	O75153
ANDFHSPCQHFNFSV	TMEM156	131	Q8N614
ACTVSFFNITNHGFL	TRIM5	446	Q9C035
FCLGNTSECFQNFSQ	TMEM116	41	Q8NCL8
DCGEIFSSNSNFAQH	ZNF534	231	Q76KX8
HFVGLNFNSNFNFAL	NF1	2376	P21359
EANNAFFAASEQTFH	TOX3	41	O15405
HCELFFNSFQGFFVS	PTH2R	396	P49190
DNNCHFDAALVSFIN	SLC6A17	326	Q9H1V8
SNFNEDHSFCETFQQ	ZNF407	1156	Q9C0G0
EAACNASNTHIFTFQ	TBX21	281	Q9UL17
FDAQANNCLTFTFGH	WFIKKN2	346	Q8TEU8
SKFHLCANFFQENPT	MYO5C	581	Q9NQX4