Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA cap binding	CYFIP1 NCBP1 EIF3D CYFIP2	2.37e-07	21	52	4	GO:0000339
GeneOntologyMolecularFunction	RNA 7-methylguanosine cap binding	CYFIP1 NCBP1 CYFIP2	5.94e-06	14	52	3	GO:0000340
GeneOntologyMolecularFunction	olfactory receptor activity	OR51G2 OR7A5 OR5B12 OR13C5 OR7D2 OR1S2 OR1G1 OR7A10	1.45e-05	431	52	8	GO:0004984
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	CACNA1A CACNA1B	2.37e-04	9	52	2	GO:0099511
GeneOntologyMolecularFunction	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	CACNA1A CACNA1B	2.37e-04	9	52	2	GO:0099626
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1A CACNA1B	5.93e-04	14	52	2	GO:0008331
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR51G2 OR7A5 OR5B12 OR13C5 OR7D2 OR1S2 OR1G1 OR7A10	1.00e-05	432	51	8	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR51G2 OR7A5 OR5B12 OR13C5 OR7D2 OR1S2 OR1G1 OR7A10	1.71e-05	465	51	8	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR51G2 OR7A5 OR5B12 OR13C5 OR7D2 OR1S2 OR1G1 OR7A10	2.31e-05	485	51	8	GO:0050907
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR51G2 OR7A5 OR5B12 OR13C5 OR7D2 OR1S2 OR1G1 OR7A10	4.01e-05	524	51	8	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR51G2 OR7A5 OR5B12 OR13C5 OR7D2 OR1S2 OR1G1 OR7A10	5.42e-05	547	51	8	GO:0007606
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR51G2 OR7A5 OR5B12 OR13C5 OR7D2 OR1S2 OR1G1 OR7A10	8.37e-05	582	51	8	GO:0050906
GeneOntologyBiologicalProcess	positive regulation of RNA binding	NCBP1 EIF3D	8.93e-05	6	51	2	GO:1905216
GeneOntologyBiologicalProcess	lamellipodium organization	ABLIM1 CYFIP1 ENPP2 CARMIL1	1.05e-04	99	51	4	GO:0097581
GeneOntologyBiologicalProcess	cap-dependent translational initiation	NCBP1 EIF3D	1.25e-04	7	51	2	GO:0002191
GeneOntologyBiologicalProcess	positive regulation of lamellipodium organization	CYFIP1 ENPP2 CARMIL1	1.32e-04	40	51	3	GO:1902745
GeneOntologyBiologicalProcess	regulation of RNA binding	NCBP1 EIF3D	1.66e-04	8	51	2	GO:1905214
GeneOntologyBiologicalProcess	positive regulation of neurotrophin TRK receptor signaling pathway	CYFIP1 CYFIP2	1.66e-04	8	51	2	GO:0051388
GeneOntologyBiologicalProcess	regulation of actomyosin structure organization	ARHGEF10 CARMIL1 SERPINF2 HDAC2	2.35e-04	122	51	4	GO:0110020
GeneOntologyBiologicalProcess	regulation of actin cytoskeleton organization	CYFIP1 ARHGEF10 CARMIL1 SERPINF2 CYFIP2 HDAC2	3.56e-04	384	51	6	GO:0032956
GeneOntologyBiologicalProcess	detection of stimulus	OR51G2 OR7A5 OR5B12 OR13C5 OR7D2 OR1S2 OR1G1 OR7A10	3.64e-04	722	51	8	GO:0051606
GeneOntologyBiologicalProcess	regulation of lamellipodium organization	CYFIP1 ENPP2 CARMIL1	3.79e-04	57	51	3	GO:1902743
GeneOntologyBiologicalProcess	positive regulation of stress fiber assembly	ARHGEF10 CARMIL1 SERPINF2	4.20e-04	59	51	3	GO:0051496
GeneOntologyBiologicalProcess	response to amyloid-beta	CACNA1A CACNA1B HDAC2	4.63e-04	61	51	3	GO:1904645
MousePheno	enhanced behavioral response to xenobiotic	CACNA1A CACNA1B LYST CYFIP2	2.00e-05	69	33	4	MP:0009746
Domain	Cytoplasmic_FMR1-int	CYFIP1 CYFIP2	7.90e-06	2	53	2	IPR008081
Domain	FragX_IP	CYFIP1 CYFIP2	7.90e-06	2	53	2	PF05994
Domain	Olfact_rcpt	OR51G2 OR7A5 OR5B12 OR13C5 OR7D2 OR1S2 OR1G1 OR7A10	1.39e-05	393	53	8	IPR000725
Domain	DUF1394	CYFIP1 CYFIP2	4.72e-05	4	53	2	PF07159
Domain	DUF1394	CYFIP1 CYFIP2	4.72e-05	4	53	2	IPR009828
Domain	VDCC_a1su_IQ	CACNA1A CACNA1B	1.64e-04	7	53	2	IPR014873
Domain	GPHH	CACNA1A CACNA1B	1.64e-04	7	53	2	PF16905
Domain	GPHH_dom	CACNA1A CACNA1B	1.64e-04	7	53	2	IPR031649
Domain	Ca_chan_IQ	CACNA1A CACNA1B	1.64e-04	7	53	2	SM01062
Domain	Ca_chan_IQ	CACNA1A CACNA1B	1.64e-04	7	53	2	PF08763
Domain	VDCCAlpha1	CACNA1A CACNA1B	3.50e-04	10	53	2	IPR002077
Domain	GPCR_Rhodpsn_7TM	OR51G2 OR7A5 OR5B12 OR13C5 OR7D2 OR1S2 OR1G1 OR7A10	5.59e-04	670	53	8	IPR017452
Domain	7tm_1	OR51G2 OR7A5 OR5B12 OR13C5 OR7D2 OR1S2 OR1G1 OR7A10	5.99e-04	677	53	8	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR51G2 OR7A5 OR5B12 OR13C5 OR7D2 OR1S2 OR1G1 OR7A10	6.47e-04	685	53	8	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR51G2 OR7A5 OR5B12 OR13C5 OR7D2 OR1S2 OR1G1 OR7A10	6.85e-04	691	53	8	PS50262
Domain	GPCR_Rhodpsn	OR51G2 OR7A5 OR5B12 OR13C5 OR7D2 OR1S2 OR1G1 OR7A10	6.92e-04	692	53	8	IPR000276
Domain	PH_dom-like	RASGRF2 ARHGEF10 ARHGAP26 PSD3 LYST	7.05e-03	426	53	5	IPR011993
Domain	Cyt_P450_CS	CYP3A7 CYP11B1	9.93e-03	53	53	2	IPR017972
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR51G2 OR7A5 OR5B12 OR13C5 OR7D2 OR1S2 OR1G1 OR7A10	3.83e-05	389	47	8	M14091
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR51G2 OR7A5 OR5B12 OR13C5 OR7D2 OR1S2 OR1G1 OR7A10	6.26e-05	417	47	8	M4072
Pubmed	The human olfactory receptor gene family.	OR51G2 OR7A5 OR5B12 OR13C5 OR7D2 OR1S2 OR1G1 OR7A10	1.56e-06	541	53	8	14983052
Pubmed	A novel deletion mutation in the TUSC3 gene in a consanguineous Pakistani family with autosomal recessive nonsyndromic intellectual disability.	TUSC3 TRAPPC9	2.28e-06	2	53	2	21513506
Pubmed	Stable respiratory activity requires both P/Q-type and N-type voltage-gated calcium channels.	CACNA1A CACNA1B	2.28e-06	2	53	2	23426690
Pubmed	Different dysregulations of CYFIP1 and CYFIP2 in distinct types of dementia.	CYFIP1 CYFIP2	2.28e-06	2	53	2	38128786
Pubmed	C57BL/6N mutation in cytoplasmic FMRP interacting protein 2 regulates cocaine response.	CYFIP1 CYFIP2	2.28e-06	2	53	2	24357318
Pubmed	Synthetic Aβ oligomers (Aβ(1-42) globulomer) modulate presynaptic calcium currents: prevention of Aβ-induced synaptic deficits by calcium channel blockers.	CACNA1A CACNA1B	2.28e-06	2	53	2	23376566
Pubmed	CaV 2.1 α1 subunit motifs that control presynaptic CaV 2.1 subtype abundance are distinct from CaV 2.1 preference.	CACNA1A CACNA1B	2.28e-06	2	53	2	38155373
Pubmed	Cytoplasmic FMR1 interacting protein (CYFIP) family members and their function in neural development and disorders.	CYFIP1 CYFIP2	2.28e-06	2	53	2	34327661
Pubmed	Cytoplasmic FMRP interacting protein 1/2 (CYFIP1/2) expression analysis in autism.	CYFIP1 CYFIP2	2.28e-06	2	53	2	29752658
Pubmed	Protein interactome and cell-type expression analyses reveal that cytoplasmic FMR1-interacting protein 1 (CYFIP1), but not CYFIP2, associates with astrocytic focal adhesion.	CYFIP1 CYFIP2	2.28e-06	2	53	2	35567753
Pubmed	Expression analysis of P/Q-type Ca2+ channel alpha 1A subunit mRNA in olfactory mitral cell in N-type Ca2+ channel alpha 1B subunit gene-deficient mice.	CACNA1A CACNA1B	2.28e-06	2	53	2	15050706
Pubmed	Cyfip1 Haploinsufficiency Increases Compulsive-Like Behavior and Modulates Palatable Food Intake in Mice: Dependence on Cyfip2 Genetic Background, Parent-of Origin, and Sex.	CYFIP1 CYFIP2	2.28e-06	2	53	2	31324746
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	MYOF ABLIM1 CYFIP1 IPO9 SARS1 UBE2N NCBP1 EIF3D THOC5 CYFIP2 HDAC2	2.30e-06	1247	53	11	27684187
Pubmed	NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons.	CYFIP1 ARHGAP26 CYFIP2	5.04e-06	22	53	3	21946561
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	CYFIP1 IPO9 SARS1 UBE2N FANCI NCBP1 EIF3D HDAC2	5.26e-06	638	53	8	33239621
Pubmed	Munc13-3 Is Required for the Developmental Localization of Ca2+ Channels to Active Zones and the Nanopositioning of Cav2.1 Near Release Sensors.	CACNA1A CACNA1B	6.83e-06	3	53	2	29466725
Pubmed	Ankyrin-B regulates Cav2.1 and Cav2.2 channel expression and targeting.	CACNA1A CACNA1B	6.83e-06	3	53	2	24394417
Pubmed	The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels.	CACNA1A CACNA1B	6.83e-06	3	53	2	38996073
Pubmed	Distinct roles for Cav2.1-2.3 in activity-dependent synaptic dynamics.	CACNA1A CACNA1B	6.83e-06	3	53	2	24523520
Pubmed	Molecular moieties masking Ca2+-dependent facilitation of voltage-gated Cav2.2 Ca2+ channels.	CACNA1A CACNA1B	6.83e-06	3	53	2	29208674
Pubmed	Molecular Basis of Regulating High Voltage-Activated Calcium Channels by S-Nitrosylation.	CACNA1A CACNA1B	6.83e-06	3	53	2	26507659
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	ABLIM1 CYFIP1 RASGRF2 ARHGEF10 FANCI ARHGAP26 EIF3D THOC5 HDAC2	9.19e-06	916	53	9	32203420
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	BLM ABLIM1 CYFIP1 IPO9 AXL FANCI TUSC3 NCBP1 FOXG1 CYFIP2	1.19e-05	1203	53	10	29180619
Pubmed	Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry.	CACNA1A CACNA1B	1.36e-05	4	53	2	32616470
Pubmed	Constitutive and ghrelin-dependent GHSR1a activation impairs CaV2.1 and CaV2.2 currents in hypothalamic neurons.	CACNA1A CACNA1B	1.36e-05	4	53	2	26283199
Pubmed	Five genes from chromosomal band 8p22 are significantly down-regulated in ovarian carcinoma: N33 and EFA6R have a potential impact on overall survival.	TUSC3 PSD3	1.36e-05	4	53	2	16270321
Pubmed	A protein phosphatase 2calpha-Ca2+ channel complex for dephosphorylation of neuronal Ca2+ channels phosphorylated by protein kinase C.	CACNA1A CACNA1B	1.36e-05	4	53	2	15728831
Pubmed	The MAP1B-LC1/UBE2L3 complex catalyzes degradation of cell surface CaV2.2 channels.	CACNA1A CACNA1B	1.36e-05	4	53	2	25483588
Pubmed	Cerebellar granule cell signaling is indispensable for normal motor performance.	CACNA1A CACNA1B	1.36e-05	4	53	2	37141091
Pubmed	Interchangeable functions of Arabidopsis PIROGI and the human WAVE complex subunit SRA1 during leaf epidermal development.	CYFIP1 CYFIP2	1.36e-05	4	53	2	15294869
Pubmed	Interactions of Rabconnectin-3 with Cav2 calcium channels.	CACNA1A CACNA1B	1.36e-05	4	53	2	31253182
Pubmed	Gender matters: estrogen receptor alpha (ERα) and histone deacetylase (HDAC) 1 and 2 control the gender-specific transcriptional regulation of human uridine diphosphate glucuronosyltransferases genes (UGT1A).	UGT1A1 HDAC2	1.36e-05	4	53	2	23714156
Pubmed	Retrolinkin recruits the WAVE1 protein complex to facilitate BDNF-induced TrkB endocytosis and dendrite outgrowth.	CYFIP1 CYFIP2	1.36e-05	4	53	2	27605705
Pubmed	Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN.	CYFIP1 CYFIP2	1.36e-05	4	53	2	20228810
Pubmed	G protein-gated inhibitory module of N-type (ca(v)2.2) ca2+ channels.	CACNA1A CACNA1B	1.36e-05	4	53	2	15953418
Pubmed	The GAS6-AXL signaling network is a mesenchymal (Mes) molecular subtype-specific therapeutic target for ovarian cancer.	AXL LYST	1.36e-05	4	53	2	27703030
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR7A5 OR5B12 OR7D2 OR1S2 OR7A10	2.12e-05	219	53	5	12213199
Pubmed	Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits.	CACNA1A CACNA1B	2.27e-05	5	53	2	8825650
Pubmed	Identification of a cardiac isoform of the murine calcium channel alpha1C (Cav1.2-a) subunit and its preferential binding with the beta2 subunit.	CACNA1A CACNA1B	2.27e-05	5	53	2	16787652
Pubmed	Transcriptional repression of human immunodeficiency virus type 1 by AP-4.	TFAP4 HDAC2	2.27e-05	5	53	2	16540471
Pubmed	Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.	CACNA1A CACNA1B	2.27e-05	5	53	2	15451373
Pubmed	Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.	CACNA1A CACNA1B	2.27e-05	5	53	2	11296258
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	MYOF ABLIM1 ARHGEF10 MLC1 PSD3	2.42e-05	225	53	5	12168954
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	BLM ABLIM1 CYFIP1 IPO9 UBE2N CARMIL1 ARHGAP26 EIF3D TRAPPC9 HDAC2	2.66e-05	1321	53	10	27173435
Pubmed	An action potential initiation mechanism in distal axons for the control of dopamine release.	CACNA1A CACNA1B	3.40e-05	6	53	2	35324301
Pubmed	A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P.	CYFIP1 CYFIP2	3.40e-05	6	53	2	11438699
Pubmed	Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.	CACNA1A CACNA1B	3.40e-05	6	53	2	12827191
Pubmed	Differential cell-type-expression of CYFIP1 and CYFIP2 in the adult mouse hippocampus.	CYFIP1 CYFIP2	3.40e-05	6	53	2	31853374
Pubmed	Visualizing an olfactory sensory map.	OR7A5 OR7A10	3.40e-05	6	53	2	8929536
Pubmed	Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors.	CACNA1A CACNA1B	3.40e-05	6	53	2	9238069
Pubmed	beta subunit reshuffling modifies N- and P/Q-type Ca2+ channel subunit compositions in lethargic mouse brain.	CACNA1A CACNA1B	3.40e-05	6	53	2	10328888
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ABLIM1 CYFIP1 ARHGEF10 CARMIL1 PSD3 CYFIP2	4.31e-05	421	53	6	36976175
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ABLIM1 IPO9 ARHGEF10 CARMIL1 PSD3 SRPK3 LYST TRAPPC9	4.52e-05	861	53	8	36931259
Pubmed	Smaller Body Size, Early Postnatal Lethality, and Cortical Extracellular Matrix-Related Gene Expression Changes of Cyfip2-Null Embryonic Mice.	CYFIP1 CYFIP2	4.76e-05	7	53	2	30687000
Pubmed	Rebuilding essential active zone functions within a synapse.	CACNA1A CACNA1B	4.76e-05	7	53	2	35176221
Pubmed	Aly and THO are required for assembly of the human TREX complex and association of TREX components with the spliced mRNA.	NCBP1 THOC5	6.34e-05	8	53	2	23222130
Pubmed	Genome-wide atlas of gene expression in the adult mouse brain.	AXL TFAP4 FOXG1	7.84e-05	54	53	3	17151600
Pubmed	International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.	CACNA1A CACNA1B	8.15e-05	9	53	2	16382099
Pubmed	Neurodevelopmental disorder-associated CYFIP2 regulates membraneless organelles and eIF2α phosphorylation via protein interactors and actin cytoskeleton.	CYFIP1 CYFIP2	8.15e-05	9	53	2	38981622
Pubmed	mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3.	NCBP1 THOC5	1.02e-04	10	53	2	26382858
Pubmed	Homozygosity mapping in 64 Syrian consanguineous families with non-specific intellectual disability reveals 11 novel loci and high heterogeneity.	TUSC3 TRAPPC9	1.02e-04	10	53	2	21629298
Pubmed	MRN complex-dependent recruitment of ubiquitylated BLM helicase to DSBs negatively regulates DNA repair pathways.	BLM UBE2N	1.02e-04	10	53	2	29523790
Pubmed	Abi1 is essential for the formation and activation of a WAVE2 signalling complex.	CYFIP1 CYFIP2	1.02e-04	10	53	2	15048123
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	DNAH3 SARS1 UBE2N SLC26A9 NCBP1 EIF3D OR7A10	1.22e-04	736	53	7	29676528
Pubmed	Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication.	NCBP1 THOC5	1.49e-04	12	53	2	18974867
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	IPO9 SARS1 UBE2N CARMIL1 EIF3D TFAP4	1.65e-04	538	53	6	28524877
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR51G2 OR7A5 OR5B12 OR1S2 OR7A10	1.69e-04	340	53	5	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR51G2 OR7A5 OR5B12 OR1S2 OR7A10	1.69e-04	340	53	5	11802173
Pubmed	Deficiency of the neurodevelopmental disorder-associated gene Cyfip2 alters the retinal ganglion cell properties and visual acuity.	CYFIP1 CYFIP2	1.76e-04	13	53	2	34508581
Pubmed	Human mRNA export machinery recruited to the 5' end of mRNA.	NCBP1 THOC5	1.76e-04	13	53	2	17190602
Pubmed	Evolution of odorant receptors expressed in mammalian testes.	OR7A5 OR7A10	1.76e-04	13	53	2	11014824
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR51G2 OR7A5 OR5B12 OR1S2 OR7A10	1.76e-04	343	53	5	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR51G2 OR7A5 OR5B12 OR1S2 OR7A10	1.84e-04	346	53	5	14611657
Pubmed	Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.	CACNA1A CACNA1B	2.05e-04	14	53	2	21228161
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNA1A CACNA1B	2.36e-04	15	53	2	20188150
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNA1A CACNA1B	2.36e-04	15	53	2	24453333
Pubmed	A genome-wide association study of brain lesion distribution in multiple sclerosis.	ARHGEF10 TRAPPC9	2.70e-04	16	53	2	23412934
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CACNA1A ABLIM1 CYFIP1 SARS1 CARMIL1 ARHGAP26 PSD3 TRAPPC9 CYFIP2	2.85e-04	1431	53	9	37142655
Pubmed	Chromosomal location-dependent nonstochastic onset of odor receptor expression.	OR7A5 OR7A10	3.05e-04	17	53	2	20668191
Pubmed	Genetic polymorphisms in phase I and phase II enzymes and breast cancer risk associated with menopausal hormone therapy in postmenopausal women.	UGT1A1 CYP3A7	3.05e-04	17	53	2	19424794
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	IPO9 AXL FANCI CYFIP2	3.22e-04	214	53	4	22199357
Pubmed	A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.	MYOF ABLIM1 NCBP1 BACE2 HDAC2	3.26e-04	392	53	5	33144569
Pubmed	In mouse brain profilin I and profilin II associate with regulators of the endocytic pathway and actin assembly.	CYFIP1 CYFIP2	3.43e-04	18	53	2	9463375
Pubmed	IKK-Mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5.	CYFIP1 SARS1 NCBP1 CYFIP2	3.64e-04	221	53	4	31950832
Pubmed	Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.	CACNA1A MLC1 CARMIL1 ARHGAP26 PSD3	3.79e-04	405	53	5	38187761
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	MYOF CYFIP1 AXL EIF3D LYST CYFIP2 HDAC2	4.43e-04	910	53	7	36736316
Pubmed	Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner.	ABLIM1 IPO9 MLC1 PSD3	4.44e-04	233	53	4	29518331
Pubmed	FGF signaling regulates otic placode induction and refinement by controlling both ectodermal target genes and hindbrain Wnt8a.	SLC26A9 FOXG1	4.70e-04	21	53	2	20171206
Pubmed	Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene.	ABLIM1 SMTNL2	5.16e-04	22	53	2	22305495
Pubmed	The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.	OR7A5 OR7A10	5.65e-04	23	53	2	10706615
Pubmed	Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans.	MBTD1 HDAC2	5.65e-04	23	53	2	14966270
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	ABLIM1 CYFIP1 UBE2N CYFIP2	5.88e-04	251	53	4	27507650
Pubmed	Patterned expression of ion channel genes in mouse dorsal raphe nucleus determined with the Allen Mouse Brain Atlas.	CACNA1A CACNA1B	6.16e-04	24	53	2	22534482
Pubmed	Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.	OR7A5 OR7A10	6.16e-04	24	53	2	9119360
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	OR51G2 CYFIP2	6.16e-04	24	53	2	32212159
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA1A ABLIM1 CYFIP1 UBE2N FOXG1 CYFIP2 HDAC2	6.20e-04	963	53	7	28671696
Pubmed	Expression of members of the putative olfactory receptor gene family in mammalian germ cells.	OR7A5 OR7D2	6.68e-04	25	53	2	1370859
Pubmed	Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures.	OR7A5 OR7A10	7.80e-04	27	53	2	32061665
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	MYOF ARHGAP26 PSD3 HDAC2	7.93e-04	272	53	4	31010829
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	BLM UBE2N FANCI NCBP1 TFAP4 THOC5 HDAC2	8.40e-04	1014	53	7	32416067
Interaction	NYAP1 interactions	CYFIP1 ARHGAP26 CYFIP2	4.04e-06	13	50	3	int:NYAP1
Interaction	MYO16 interactions	CYFIP1 ARHGAP26 CYFIP2	7.87e-06	16	50	3	int:MYO16
Interaction	NYAP2 interactions	CYFIP1 ARHGAP26 CYFIP2	2.46e-05	23	50	3	int:NYAP2
Cytoband	Ensembl 112 genes in cytogenetic band chr8p22	TUSC3 PSD3	1.37e-03	47	53	2	chr8p22
Cytoband	15q26.1	BLM FANCI	1.80e-03	54	53	2	15q26.1
Cytoband	Ensembl 112 genes in cytogenetic band chr22q12	EIF3D THOC5 SLC5A4	2.57e-03	235	53	3	chr22q12
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(other)\|COVID-19 / group, cell type (main and fine annotations)	ABLIM1 RASGRF2 ARHGEF10 TUSC3 SLC5A4	2.45e-06	181	53	5	26eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	ABLIM1 RASGRF2 ENPP2 BACE2 SLC5A4	2.72e-06	185	53	5	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	human_hepatoblastoma-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	RASGRF2 ARHGAP26 FAXDC2 SERPINF2 LYST	2.87e-06	187	53	5	f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCell	Control-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	MYOF RASGRF2 ENPP2 BACE2 SERPINF2	2.87e-06	187	53	5	5429ae85942b8ec3895cceb63c663de3c24ca064
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	ABLIM1 RASGRF2 ENPP2 TUSC3 SLC5A4	2.95e-06	188	53	5	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	COVID-19-Endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	ABLIM1 RASGRF2 ARHGEF10 TUSC3 SLC5A4	3.10e-06	190	53	5	9fbd92cd6d4683b2490504d29c43cf42020433d4
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RASGRF2 ENPP2 TUSC3 SLC5A4	4.23e-05	163	53	4	ba7d02db0f0e2f9916ec8db52c067c87b6917c23
ToppCell	facs-Marrow-KLS-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGT1A1 AXL ENPP2 DENND2C	4.44e-05	165	53	4	4f95c2fe5ab4416c736fe0d1936695a2b26777eb
ToppCell	facs-Marrow-KLS-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UGT1A1 AXL ENPP2 DENND2C	4.44e-05	165	53	4	3e913b49a868fdd5589200ae3e9be77c0938ba14
ToppCell	PBMC-Mild-cDC_11\|Mild / Compartment, Disease Groups and Clusters	ENPP2 CARMIL1 SERPINF2 CYFIP2	5.83e-05	177	53	4	974305e4c0eff90134c4e58cf11b955d1eee0501
ToppCell	Adult-Endothelial-endothelial_cell_of_bronchial_vessel-D175\|Adult / Lineage, Cell type, age group and donor	ABLIM1 ENPP2 TUSC3 BACE2	5.83e-05	177	53	4	c9f269765c7d5d29caab75910e51645606ed562e
ToppCell	367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)\|367C / Donor, Lineage, Cell class and subclass (all cells)	CYP3A7 ARHGEF10 TUSC3 FAXDC2	6.23e-05	180	53	4	162cec1734e560c068cd61717e40e18dcf92308c
ToppCell	367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	CYP3A7 ARHGEF10 TUSC3 FAXDC2	6.23e-05	180	53	4	33c86c22ba877358cd8c1e39b5c0b3dc3a45b7dd
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	ABLIM1 RASGRF2 ENPP2 TUSC3	6.78e-05	184	53	4	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	PBMC-Mild-cDC_9\|Mild / Compartment, Disease Groups and Clusters	CACNA1B MYOF ARHGEF10 PSD3	6.78e-05	184	53	4	2e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCell	IPF-Myeloid-DC_Langerhans\|IPF / Disease state, Lineage and Cell class	AXL ENPP2 SERPINF2 CYFIP2	6.92e-05	185	53	4	f8ee3cb2aa9ec70f9ce8797be2b155da27ef6464
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CACNA1A ABLIM1 AXL CARMIL1	6.92e-05	185	53	4	fcd95bc074e982fc7b8fd48d2e80038b9ea35ebb
ToppCell	Control-Endothelial_cells-Arterial_endothelial_cells\|Control / group, cell type (main and fine annotations)	ABLIM1 RASGRF2 ENPP2 ARHGAP26	7.22e-05	187	53	4	81affaab3fe3e1daea45ada6445e906ddd33950e
ToppCell	Control-Endothelial-VE_Peribronchial\|Control / Disease state, Lineage and Cell class	ABLIM1 RASGRF2 ENPP2 BACE2	7.37e-05	188	53	4	f5b7dbc89f992c13280d36a34935be83906b1bc0
ToppCell	Control-Endothelial-VE_Peribronchial\|World / Disease state, Lineage and Cell class	ABLIM1 RASGRF2 ENPP2 BACE2	7.52e-05	189	53	4	c76d8af2e0aa4a83ee0c3439c894566fbf117dd3
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(general)\|COVID-19 / group, cell type (main and fine annotations)	RASGRF2 ARHGEF10 TUSC3 SLC5A4	7.68e-05	190	53	4	812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCell	COVID-19-lung-Artery_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RASGRF2 ENPP2 TUSC3 SLC5A4	7.68e-05	190	53	4	07b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABLIM1 RASGRF2 ENPP2 TUSC3	7.83e-05	191	53	4	50601ef0a5a8f2c2120922989e08e85bf2d9b4ab
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CACNA1A ABLIM1 AXL CARMIL1	7.99e-05	192	53	4	32927ef3b93e0497e9bbe63c2754da03cf178202
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-SVEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABLIM1 RASGRF2 ENPP2 BACE2	7.99e-05	192	53	4	c3dda7c48732b0b8bde36de282d64192f5e9b98f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	MYOF AXL ARHGAP26 PSD3	7.99e-05	192	53	4	8b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell	IPF-Endothelial-VE_Arterial\|IPF / Disease state, Lineage and Cell class	ABLIM1 RASGRF2 ENPP2 TUSC3	8.15e-05	193	53	4	bf83b1fe9d38408f30eee4eb634341c04ef82791
ToppCell	IPF-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	ABLIM1 RASGRF2 ENPP2 TUSC3	8.15e-05	193	53	4	70a9aadda83a97e06e9bc2d1327ce60dd3c58767
ToppCell	IPF-Endothelial-VE_Peribronchial\|World / Disease state, Lineage and Cell class	ABLIM1 RASGRF2 ENPP2 BACE2	8.49e-05	195	53	4	120296531bbc8080dcabacbd64733cc1dc34603a
ToppCell	IPF-Endothelial-VE_Peribronchial\|IPF / Disease state, Lineage and Cell class	ABLIM1 RASGRF2 ENPP2 BACE2	8.49e-05	195	53	4	2c3ad3cb79f11119ac69c413a938d21199145040
ToppCell	NS-moderate-d_16-33-Epithelial-Secretory\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MYOF ABLIM1 CARMIL1 BACE2	8.65e-05	196	53	4	70384c1da9baed843f414cfd1403ddd586a2db07
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RASGRF2 ENPP2 TUSC3 SLC5A4	8.65e-05	196	53	4	915e4a7422058be246b54760df31e8a607310625
ToppCell	critical-Epithelial-Secretory\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MYOF ABLIM1 CARMIL1 BACE2	8.65e-05	196	53	4	7da687eb983a54c28ee990424cc52e01caf5f4aa
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Naive_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	ABLIM1 RASGRF2 ARHGEF10 CYFIP2	8.83e-05	197	53	4	836dd8110d5689f944ad1d301def38c32278b5b5
ToppCell	moderate-Epithelial-Secretory\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MYOF ABLIM1 CARMIL1 BACE2	9.00e-05	198	53	4	7d96d7105a849c7280ce87bd76ce130ac47384fd
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	MYOF RASGRF2 ENPP2 BACE2	9.00e-05	198	53	4	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_macrophage\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MYOF CYFIP1 AXL ENPP2	9.00e-05	198	53	4	9aaff68107ae4542f904b142d23669f2fcd557ac
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RASGRF2 ENPP2 TUSC3 SLC5A4	9.00e-05	198	53	4	002424b24dacac553e02d0f764a6e8a1e567b9df
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MYOF CYFIP1 AXL ENPP2	9.00e-05	198	53	4	5aaf3861c53763cf09bb628c9d2eabb6a7277021
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Erythrophagocytic_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	MYOF CYFIP1 AXL ENPP2	9.18e-05	199	53	4	78db2e3b85356ed2f08794e5a97c16a220f8a076
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac\|lymph-node_spleen / Manually curated celltypes from each tissue	MYOF CYFIP1 AXL ENPP2	9.18e-05	199	53	4	c051cc3e42cfa2ec09fd8dae1172af350bb2dfcb
ToppCell	Macroglial-Astrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ABLIM1 MLC1 CARMIL1 ARHGAP26	9.36e-05	200	53	4	941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Mesenchymal-Mesoderm\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	CACNA1A LETM2 RASGRF2 PSD3	9.36e-05	200	53	4	0f4b8b0868bda406fe6bf01d1b722510fdfd0168
ToppCell	(50)_cDC2\|World / shred on Cell_type and subtype	MYOF AXL ENPP2 SERPINF2	1.05e-04	206	53	4	d519adeb8290fcce107e81a439ba3bf1e231b55b
Drug	AC1L1JG6	CACNA1A CACNA1B ENPP2	4.26e-06	14	53	3	CID000005026
Drug	Aconitine [302-27-2]; Down 200; 6.2uM; MCF7; HT_HG-U133A	MYOF MBTD1 IPO9 ARHGEF10 ARHGAP26 TFAP4	6.36e-06	197	53	6	6797_DN
Drug	AC 110	CACNA1A CACNA1B	3.18e-05	4	53	2	CID000022860
Drug	S 8510	CACNA1A CACNA1B	5.29e-05	5	53	2	CID005488383
Drug	3,4-dihydroquinazoline	CACNA1A CACNA1B	7.93e-05	6	53	2	CID000583065
Drug	alpha-sialylcholesterol	CACNA1A CACNA1B	7.93e-05	6	53	2	CID000133976
Drug	Maprotiline hydrochloride [10347-81-6]; Up 200; 12.8uM; MCF7; HT_HG-U133A	MYOF ARHGEF10 ARHGAP26 PSD3 OR1G1	8.36e-05	192	53	5	3236_UP
Drug	Nizatidine [76963-41-2]; Down 200; 12uM; HL60; HT_HG-U133A	MYOF AXL PSD3 TFAP4 THOC5	9.00e-05	195	53	5	3047_DN
Drug	BAS 012416453; Up 200; 38uM; MCF7; HT_HG-U133A	MYOF MBTD1 PSD3 FAXDC2 THOC5	9.22e-05	196	53	5	6880_UP
Drug	Molindone hydrochloride [15622-65-8]; Up 200; 12.8uM; MCF7; HT_HG-U133A	CACNA1A MBTD1 FAXDC2 OR7A10 THOC5	9.22e-05	196	53	5	4784_UP
Drug	Phenindione [83-12-5]; Down 200; 18uM; MCF7; HT_HG-U133A	MBTD1 ABLIM1 LYST TFAP4 TRAPPC9	9.44e-05	197	53	5	2868_DN
Drug	3,4-diaminopyridine	CACNA1A CACNA1B ENPP2	9.49e-05	38	53	3	CID000005918
Drug	Morantel tartrate [26155-31-7]; Up 200; 10.8uM; PC3; HT_HG-U133A	BLM MYOF MBTD1 TFAP4 TRAPPC9	9.67e-05	198	53	5	1798_UP
Drug	Isocorydine (+) [475-67-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A	ARHGEF10 MLC1 ENPP2 TFAP4 THOC5	9.67e-05	198	53	5	6843_UP
Drug	Altretamine [654-05-6]; Down 200; 19uM; PC3; HT_HG-U133A	MBTD1 ARHGAP26 OR1G1 TRAPPC9 FOXG1	9.67e-05	198	53	5	4627_DN
Drug	Heptaminol hydrochloride [543-15-7]; Up 200; 22uM; PC3; HT_HG-U133A	MBTD1 ARHGEF10 ARHGAP26 TUSC3 THOC5	9.67e-05	198	53	5	7313_UP
Drug	Pyridoxine hydrochloride [58-56-0]; Down 200; 19.4uM; PC3; HT_HG-U133A	AXL CARMIL1 TUSC3 TRAPPC9 CYFIP2	9.67e-05	198	53	5	5813_DN
Drug	chromomycin A3	BLM CACNA1A CACNA1B FOXG1	9.75e-05	103	53	4	CID000656673
Drug	Thiethylperazine malate [52239-63-1]; Up 200; 6uM; MCF7; HT_HG-U133A	MYOF ARHGEF10 ARHGAP26 PSD3 TRAPPC9	9.90e-05	199	53	5	3576_UP
Drug	Propantheline bromide [50-34-0]; Up 200; 9uM; HL60; HT_HG-U133A	CYP3A7 OR1G1 SRPK3 TRAPPC9 CYFIP2	9.90e-05	199	53	5	3013_UP
Drug	Chloroquine diphosphate [50-63-5]; Down 200; 7.8uM; HL60; HG-U133A	DNAH3 ARHGEF10 FAXDC2 PAQR3 TRAPPC9	9.90e-05	199	53	5	1719_DN
Drug	Felbinac [5728-52-9]; Down 200; 18.8uM; HL60; HT_HG-U133A	AXL PSD3 FAXDC2 THOC5 CYFIP2	9.90e-05	199	53	5	3061_DN
Drug	aspirin, USP; Down 200; 100uM; HL60; HT_HG-U133A	CACNA1A MYOF ARHGAP26 TFAP4 TRAPPC9	1.01e-04	200	53	5	2664_DN
Drug	Hydroxyzine dihydrochloride [2192-20-3]; Up 200; 9uM; MCF7; HT_HG-U133A	MYOF ARHGAP26 PSD3 SRPK3 TFAP4	1.01e-04	200	53	5	1524_UP
Drug	APMPA	CACNA1A CACNA1B	1.11e-04	7	53	2	CID000512300
Disease	chromosome 15q11.2 deletion syndrome (implicated_via_orthology)	CYFIP1 CYFIP2	8.43e-06	3	50	2	DOID:0060393 (implicated_via_orthology)
Disease	familial hemiplegic migraine 1 (implicated_via_orthology)	CACNA1A CACNA1B	8.43e-06	3	50	2	DOID:0111181 (implicated_via_orthology)
Disease	migraine (implicated_via_orthology)	CACNA1A CACNA1B	1.68e-05	4	50	2	DOID:6364 (implicated_via_orthology)
Disease	hereditary ataxia (implicated_via_orthology)	CACNA1A CACNA1B	5.88e-05	7	50	2	DOID:0050951 (implicated_via_orthology)
Disease	MYELODYSPLASTIC SYNDROME	BLM FANCI ARHGAP26	2.03e-04	67	50	3	C3463824
Disease	response to paliperidone, schizophrenia symptom severity measurement	CACNA1B RASGRF2 TUSC3 PSD3	4.94e-04	216	50	4	EFO_0007925, EFO_0007927
Disease	temporal lobe epilepsy (is_marker_for)	CYFIP1 HDAC2	5.24e-04	20	50	2	DOID:3328 (is_marker_for)
Disease	prostate carcinoma (is_marker_for)	SARS1 HDAC2	6.96e-04	23	50	2	DOID:10286 (is_marker_for)
Disease	Acute monocytic leukemia	BLM FANCI	8.91e-04	26	50	2	C0023465
Disease	Miller Dieker syndrome	BLM FANCI	1.11e-03	29	50	2	C0265219
Disease	temporal lobe epilepsy (biomarker_via_orthology)	CACNA1A CYFIP1	1.27e-03	31	50	2	DOID:3328 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
EYPMAAPKVRFMTKI	UBE2N	61	P61088
FVVSPPFEYTIMAMI	CACNA1A	1561	O00555
FRITILPQLYIQPMM	BACE2	371	Q9Y5Z0
LYSLMMKPIQRFPQF	ARHGEF10	556	O15013
LEPKIFPYEMLMVTN	ABLIM1	711	O14639
FTVPVEMMQARTYPL	SERPINF2	261	P08697
PPFEYFIMAMIALNT	CACNA1B	1471	Q00975
PIVQDFAPRVIVMYM	PAQR3	231	Q6TCH7
VMYTVVTPMLNPFIY	OR7A5	276	Q15622
EPEVTKLMNFMYFQR	CYFIP1	116	Q7L576
MFSKMNLQEIPPLVY	FANCI	201	Q9NVI1
FRLVPFMVFLIVPFM	LETM2	176	Q2VYF4
VYPMPRVIFRMFDYT	NCBP1	281	Q09161
MQYPFKPCMRVEVVD	MBTD1	281	Q05BQ5
CYPEMVMKLIVINFP	EPHX4	181	Q8IUS5
KPPFSYNALIMMAIR	FOXG1	181	P55316
LVQVVMGFMYLLFPP	OR51G2	276	Q8NGK0
PNPIVYMMKAFDLIV	NDUFB10	21	O96000
TDKLIFIFYRVMTPM	OR13C5	276	Q8NGS8
YLFIFITIMKMRSPE	OR5B12	216	Q96R08
EPEVTKLMKFMYFQR	CYFIP2	116	Q96F07
VMYTVVTPMLNPFIY	OR1G1	276	P47890
FTVVTPMMNPFIYSL	OR1S2	291	Q8NGQ3
MISFPMVVFLYPFLK	FAXDC2	141	Q96IV6
YKRMNMLRQKFPSVP	BLM	811	P54132
PYQEMKFFIPQLIMI	DNAH3	476	Q8TD57
FPQLMKMRYLEVSEP	EIF3D	176	O15371
IKMVYSFILRPSMFP	CYP11B1	481	P15538
EKRREMSPALVYPFM	DENND2C	611	Q68D51
FLVRMPPFTKMFLAY	LYST	3246	Q99698
APVILPEMYKIFTMA	IPO9	186	Q96P70
VAMEKNYTLRFMPIP	CARMIL1	621	Q5VZK9
MFIPKGVVVMIPSYV	CYP3A7	386	P24462
IFKPIISKVMEMYQP	HDAC2	241	Q92769
AFLVTNMVPMYPAFK	ENPP2	696	Q13822
IPIYTPFFMRKEVMQ	SARS1	221	P49591
YMHKIRFPIPTEMIV	SLC26A9	276	Q7LBE3
MLETFLTYPMFQIPR	RASGRF2	376	O14827
VMYTVVTPMLNPFIY	OR7A10	276	O76100
PGPLMMYQFQRSFIK	ARHGAP26	461	Q9UNA1
FVPIYIKSGVMTMPE	SLC5A4	116	Q9NY91
VMYTVVTPMLNPFIY	OR7D2	276	Q96RA2
MNETIFMKFRVPAPF	SIX6OS1	161	Q8N1H7
TQFSAFLLPMMEYIP	SRPK3	536	Q9UPE1
FLLPMMEYIPEKRAS	SRPK3	541	Q9UPE1
FIKAPPRNYSMIVMF	TUSC3	76	Q13454
PRNYSMIVMFTALQP	TUSC3	81	Q13454
VKDYPRPIMPNMVFV	UGT1A1	261	P22309
PVYLPTQMLVKFMAD	AXL	641	P30530
VMGRKPDPMCVFTYV	SMTNL2	436	Q2TAL5
VQLMVYNPMPFELRV	TRAPPC9	601	Q96Q05
IMQASLPVQEYLFMP	THOC5	236	Q13769
YFSFEMPLTPMIQQR	PSD3	471	Q9NYI0
MEYFMVPTQKVPSLQ	TFAP4	1	Q01664
FSIMRIVEMFKDYPP	MLC1	281	Q15049
VLFMKVFLPKEELYM	MYOF	1356	Q9NZM1