Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction6-phosphofructokinase activity

PFKM PFKP

2.66e-053602GO:0003872
GeneOntologyMolecularFunctionfructose-6-phosphate binding

PFKM PFKP

8.83e-055602GO:0070095
GeneOntologyMolecularFunctionphosphofructokinase activity

PFKM PFKP

1.85e-047602GO:0008443
GeneOntologyBiologicalProcessimmunoglobulin production

IGKV1-16 IGKV1-5 IGKV1-6 CD28 IGKV1D-43 TRAV38-1 IGKV1D-8 IGKV4-1

5.34e-07241618GO:0002377
GeneOntologyBiologicalProcessproduction of molecular mediator of immune response

IGKV1-16 IGKV1-5 IGKV1-6 CD28 IGKV1D-43 TRAV38-1 IGKV1D-8 IGKV4-1

2.36e-05403618GO:0002440
GeneOntologyBiologicalProcessadaptive immune response

IGKV1-16 IGKV1-5 IGKV1-6 PPP3CB CD28 JAG1 IGKV1D-43 TRAV38-1 IGKV1D-8 IGKV4-1 CFHR4

3.04e-058386111GO:0002250
GeneOntologyCellularComponentimmunoglobulin complex

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-8 IGKV4-1

1.17e-05166646GO:0019814
GeneOntologyCellularComponent6-phosphofructokinase complex

PFKM PFKP

2.76e-053642GO:0005945
GeneOntologyCellularComponentouter dynein arm

DNAI1 DNAH9

5.97e-0412642GO:0036157
GeneOntologyCellularComponentdynein complex

DNAI1 DYNC2H1 DNAH9

6.07e-0454643GO:0030286
DomainPHOSPHOFRUCTOKINASE

PFKM PFKP

2.84e-053582PS00433
Domain6-Pfructokinase_euk

PFKM PFKP

2.84e-053582IPR009161
DomainPhosphofructokinase_CS

PFKM PFKP

2.84e-053582IPR015912
DomainPFK

PFKM PFKP

2.84e-053582PF00365
DomainATP_PFK

PFKM PFKP

2.84e-053582IPR022953
DomainPhosphofructokinase_dom

PFKM PFKP

2.84e-053582IPR000023
DomainDHC_N1

DYNC2H1 DNAH9

2.62e-048582PF08385
DomainDynein_heavy_dom-1

DYNC2H1 DNAH9

2.62e-048582IPR013594
DomainARM-type_fold

GBF1 PIK3C2G NBEAL1 CUL9 PSMD1 XPO1

6.26e-04339586IPR016024
DomainDynein_heavy_chain_D4_dom

DYNC2H1 DNAH9

8.42e-0414582IPR024317
DomainDynein_HC_stalk

DYNC2H1 DNAH9

8.42e-0414582IPR024743
DomainDynein_heavy_dom-2

DYNC2H1 DNAH9

8.42e-0414582IPR013602
DomainDHC_N2

DYNC2H1 DNAH9

8.42e-0414582PF08393
DomainMT

DYNC2H1 DNAH9

8.42e-0414582PF12777
DomainAAA_8

DYNC2H1 DNAH9

8.42e-0414582PF12780
DomainATPase_dyneun-rel_AAA

DYNC2H1 DNAH9

8.42e-0414582IPR011704
DomainAAA_5

DYNC2H1 DNAH9

8.42e-0414582PF07728
DomainEGF_extracell

TENM3 JAG1 LRP1B

8.58e-0460583IPR013111
DomainEGF_2

TENM3 JAG1 LRP1B

8.58e-0460583PF07974
DomainDHC_fam

DYNC2H1 DNAH9

9.70e-0415582IPR026983
DomainDynein_heavy_dom

DYNC2H1 DNAH9

9.70e-0415582IPR004273
DomainDynein_heavy

DYNC2H1 DNAH9

9.70e-0415582PF03028
DomainCarboxyPept-like_regulatory

TENM3 CILP

1.25e-0317582IPR008969
DomainNA_NEUROTRAN_SYMP_2

SLC6A3 SLC6A11

1.40e-0318582PS00754
DomainSNF

SLC6A3 SLC6A11

1.57e-0319582PF00209
DomainNA_NEUROTRAN_SYMP_1

SLC6A3 SLC6A11

1.57e-0319582PS00610
DomainNA_NEUROTRAN_SYMP_3

SLC6A3 SLC6A11

1.57e-0319582PS50267
DomainNa/ntran_symport

SLC6A3 SLC6A11

1.57e-0319582IPR000175
DomainIGv

IGKV1-5 CD28 IGKV4-1

1.64e-0375583SM00406
Domain-

ATP11B ATP13A5

4.43e-03325823.40.1110.10
Domain-

ATP11B ATP13A5

4.43e-03325822.70.150.10
DomainATPase_P-typ_cyto_domN

ATP11B ATP13A5

5.28e-0335582IPR023299
DomainP_typ_ATPase

ATP11B ATP13A5

5.58e-0336582IPR001757
DomainATPase_P-typ_P_site

ATP11B ATP13A5

5.58e-0336582IPR018303
DomainATPASE_E1_E2

ATP11B ATP13A5

5.58e-0336582PS00154
DomainATPase_P-typ_transduc_dom_A

ATP11B ATP13A5

5.89e-0337582IPR008250
DomainE1-E2_ATPase

ATP11B ATP13A5

5.89e-0337582PF00122
Domain-

PRMT5 METTL14 DNMT3A

6.17e-031205833.40.50.150
DomainSAM-dependent_MTases

PRMT5 METTL14 DNMT3A

6.46e-03122583IPR029063
Domain-

TENM3 LRP1B

6.52e-03395822.120.10.30
PathwayREACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION

IGKV1-16 IGKV1-5 PPP3CB IGKV1D-16 IGKV4-1

1.28e-0586505M27206
PathwayREACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR

IGKV1-16 IGKV1-5 PPP3CB PSMD1 IGKV1D-16 IGKV4-1

2.52e-05166506M608
PathwayREACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING

IGKV1-16 IGKV1-5 PPP3CB PSMD1 IGKV1D-16 IGKV4-1

4.77e-05186506M27175
PathwayREACTOME_COMPLEMENT_CASCADE

IGKV1-16 IGKV1-5 IGKV1D-16 IGKV4-1 CFHR4

5.23e-05115505M19752
PathwayREACTOME_CD22_MEDIATED_BCR_REGULATION

IGKV1-16 IGKV1-5 IGKV1D-16 IGKV4-1

6.30e-0561504M27581
PathwayBIOCARTA_PTDINS_PATHWAY

JAG1 PFKM PFKP

7.07e-0523503M8809
PathwayREACTOME_FCGR_ACTIVATION

IGKV1-16 IGKV1-5 IGKV1D-16 IGKV4-1

1.02e-0469504M27108
PathwayREACTOME_SCAVENGING_OF_HEME_FROM_PLASMA

IGKV1-16 IGKV1-5 IGKV1D-16 IGKV4-1

1.02e-0469504M27150
PathwayKEGG_GALACTOSE_METABOLISM

MGAM PFKM PFKP

1.03e-0426503M4377
PathwayREACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS

IGKV1-16 IGKV1-5 IGKV1D-16 IGKV4-1

1.14e-0471504M1078
PathwayREACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION

IGKV1-16 IGKV1-5 IGKV1D-16 IGKV4-1

1.14e-0471504M27203
PathwayREACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION

IGKV1-16 IGKV1-5 PSMD1 IGKV1D-16 IGKV4-1

1.16e-04136505M27207
PathwayREACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT

IGKV1-16 IGKV1-5 IGKV1D-16 IGKV4-1

1.82e-0480504M6121
PathwayREACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS

IGKV1-16 IGKV1-5 IGKV1D-16 IGKV4-1

2.00e-0482504M27110
PathwayREACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS

IGKV1-16 IGKV1-5 IGKV1D-16 IGKV4-1

2.40e-0486504M601
PathwayREACTOME_FCERI_MEDIATED_MAPK_ACTIVATION

IGKV1-16 IGKV1-5 IGKV1D-16 IGKV4-1

2.51e-0487504M27205
PathwayREACTOME_FCGR3A_MEDIATED_IL10_SYNTHESIS

IGKV1-16 IGKV1-5 IGKV1D-16 IGKV4-1

3.52e-0495504M29842
PathwayREACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS

IGKV1-16 IGKV1-5 IGKV1D-16 IGKV4-1

3.96e-0498504M27152
PathwayREACTOME_PARASITE_INFECTION

IGKV1-16 IGKV1-5 IGKV1D-16 IGKV4-1

7.49e-04116504M29843
Pubmed

Characteristics of the immunoglobulin Vkappa genes, pseudogenes, relics and orphons in the mouse genome.

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-8 IGKV4-1

1.28e-122065610427970
Pubmed

Variation in the crossover point of kappa immunoglobulin gene V-J recombination: evidence from a cryptic gene.

IGKV1-16 IGKV1-5 IGKV1-6

5.19e-0796536777049
Pubmed

Amino acid sequence of the variable region of M149 mouse myeloma light chain: comparison with the nucleotide sequence of K2 and K3 clones.

IGKV1-5 IGKV1D-43 IGKV1D-8

1.02e-06116536795447
Pubmed

Multiple related immunoglobulin variable-region genes identified by cloning and sequence analysis.

IGKV1-5 IGKV1D-43 IGKV1D-8

1.02e-0611653279004
Pubmed

Organization and complete sequence of identical embryonic and plasmacytoma kappa V-region genes.

IGKV1-5 IGKV1D-43 IGKV1D-8

1.02e-06116536767723
Pubmed

Structure and implied functions of truncated B-cell receptor mRNAs in early embryo and adult mesenchymal stem cells: Cdelta replaces Cmu in mu heavy chain-deficient mice.

IGKV1-16 IGKV1-5 IGKV1-6

3.43e-061665317124007
Pubmed

Cloning of human muscle phosphofructokinase cDNA.

PFKM PFKP

3.44e-0626522822475
Pubmed

Chimeric phosphofructokinases involving exchange of the N- and C-terminal halves of mammalian isozymes: implications for ligand binding sites.

PFKM PFKP

3.44e-06265217544406
Pubmed

Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations.

PFKM PFKP

3.44e-06265225985179
Pubmed

Human myeloperoxidase in innate and acquired immunity.

IGKV1-5 IGKV1D-43 IGKV1D-8

4.98e-061865320399194
Pubmed

Biochemical and transcript level differences between the three human phosphofructokinases show optimisation of each isoform for specific metabolic niches.

PFKM PFKP

1.03e-05365233141153
Pubmed

Phosphofructokinase (PFK) isozymes in man. I. Studies of adult human tissues.

PFKM PFKP

1.03e-053652156693
Pubmed

Protein arginine methyltransferase 5-mediated epigenetic silencing of IRX1 contributes to tumorigenicity and metastasis of gastric cancer.

PRMT5 DNMT3A

1.03e-05365229802960
Pubmed

Functional expression of human mutant phosphofructokinase in yeast: genetic defects in French Canadian and Swiss patients with phosphofructokinase deficiency.

PFKM PFKP

1.03e-0536527825568
Pubmed

Isozymes of human phosphofructokinase in blood cells and cultured cell lines: molecular and genetic evidence for a trigenic system.

PFKM PFKP

1.03e-0536526451249
Pubmed

Isozymes of human phosphofructokinase: identification and subunit structural characterization of a new system.

PFKM PFKP

1.03e-0536526444721
Pubmed

Mislocalization of DNAH5 and DNAH9 in respiratory cells from patients with primary ciliary dyskinesia.

DNAI1 DNAH9

1.03e-05365215750039
Pubmed

Genomic organization, 5'flanking region and tissue-specific expression of mouse phosphofructokinase C gene.

PFKM PFKP

1.03e-05365211137296
Pubmed

Characterization of the enzymatic defect in late-onset muscle phosphofructokinase deficiency. New subtype of glycogen storage disease type VII.

PFKM PFKP

1.03e-0536522960695
Pubmed

Phosphofructokinase isozyme expression during myoblast differentiation.

PFKM PFKP

1.03e-0536522521854
Pubmed

IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes.

IGKV1-16 IGKV1-5 IGKV1-6 IGKV4-1

1.36e-057765415608191
Pubmed

Evolution of immunoglobulin V genes: evidence indicating that recently duplicated human V kappa sequences have diverged by gene conversion.

IGKV1-16 IGKV1D-16

2.06e-0546526402305
Pubmed

Composite human VK genes and a model of their evolution.

IGKV1-5 IGKV1D-8

2.06e-0546526087279
Pubmed

PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.

PRMT5 DNMT3A

2.06e-05465219234465
Pubmed

Nuclear export of phosphorylated C/EBPbeta mediates the inhibition of albumin expression by TNF-alpha.

CEBPB XPO1

2.06e-05465211726507
Pubmed

DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm.

DNAI1 DNAH9

2.06e-05465218950741
Pubmed

GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation in a parkinsonism model.

SLC6A3 SLC6A11

3.43e-05565233009395
Pubmed

Development of monoclonal antibodies against GBF1 and their use in studying its functions.

GBF1 CEBPB

3.43e-05565216318580
Pubmed

The establishment of rotational polarity in the airway and ependymal cilia: analysis with a novel cilium motility mutant mouse.

DNAI1 DNAH9

3.43e-05565223525783
Pubmed

PDGF signalling in the dermis and in dermal condensates is dispensable for hair follicle induction and formation.

EDAR ITGA8

3.43e-05565225708924
Pubmed

Evolutionary dynamics of the human immunoglobulin kappa locus and the germline repertoire of the Vkappa genes.

IGKV1D-43 IGKV1D-16 IGKV1D-8

4.26e-053665311298326
Pubmed

Stabilization of phosphofructokinase 1 platelet isoform by AKT promotes tumorigenesis.

PFKM PFKP

5.13e-05665229038421
Pubmed

Proteomic identification of brain proteins that interact with dynein light chain LC8.

PFKM PFKP DNMT3A

6.79e-054265314760703
Pubmed

FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export.

XPO1 METTL14

7.18e-05765231340148
Pubmed

Identification of intervals on chromosomes 1, 3, and 13 linked to the development of lupus in BXSB mice.

CD28 CFHR4

7.18e-05765210693874
Pubmed

Diverse alternative back-splicing and alternative splicing landscape of circular RNAs.

XPO1 ZFX

9.56e-05865227365365
Pubmed

A regulatory circuit that involves HR23B and HDAC6 governs the biological response to HDAC inhibitors.

GBF1 PSMD1 PFKP

1.15e-045065323703321
Pubmed

RAD21 cooperates with pluripotency transcription factors in the maintenance of embryonic stem cell identity.

PRMT5 PSMD1 PFKP DNMT3A

1.65e-0414665421589869
Pubmed

Progesterone induced Warburg effect in HEK293 cells is associated with post-translational modifications and proteasomal degradation of progesterone receptor membrane component 1.

PTPRS PFKM PFKP

1.79e-045865331067491
Pubmed

Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53.

PRMT5 CUL9

1.87e-041165231570706
Pubmed

Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm.

DNAI1 DNAH9

1.87e-041165224421334
Pubmed

Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system.

SETD5 NPAS3 XPO1

1.98e-046065329055695
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

PRMT5 EIF3L PSMD1 XPO1 PFKM PFKP

1.99e-0445165636168627
Pubmed

Recruitment of phosphatidylinositol 3-kinase to CD28 inhibits HIV transcription by a Tat-dependent mechanism.

PIK3C2G CD28

2.24e-041265212077252
Pubmed

Sall1 balances self-renewal and differentiation of renal progenitor cells.

JAG1 ITGA8 CFHR4

2.74e-046765324550112
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

CEP350 GBF1 NBEAL1 PSMD1 XPO1 PFKP DNMT3A

2.99e-0468965736543142
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

CACNA2D1 ATP11B PTPRS CUL9 PSMD1

3.04e-0431365538270169
Pubmed

Extensive alternative splicing transitions during postnatal skeletal muscle development are required for calcium handling functions.

CACNA2D1 PPP3CB

3.08e-041465228826478
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CEP350 ZNF462 GBF1 DYNC2H1 PLEKHG3 N4BP2

3.20e-0449365615368895
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

PRMT5 EIF3L PSMD1 XPO1 PFKM PFKP

3.24e-0449465626831064
Pubmed

A high-resolution molecular atlas of the fetal mouse lower urogenital tract.

EDAR JAG1 DNMT3A

3.82e-047565321905163
Pubmed

CRL4B promotes tumorigenesis by coordinating with SUV39H1/HP1/DNMT3A in DNA methylation-based epigenetic silencing.

PRMT5 DNMT3A

4.06e-041665224292684
Pubmed

Role of topoisomerase IIbeta in the expression of developmentally regulated genes.

CACNA2D1 TENM3

4.06e-041665216923961
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

TENM3 DYNC2H1 PRMT5 EIF3L

4.24e-0418765426460568
Pubmed

Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?

SLC6A3 PIK3C2G PFKM PFKP

4.68e-0419265420602615
Pubmed

Rewiring of embryonic glucose metabolism via suppression of PFK-1 and aldolase during mouse chorioallantoic branching.

PFKM PFKP

5.16e-041865228049690
Pubmed

Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation.

METTL14 DNMT3A

5.16e-041865225569111
Pubmed

Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation.

JAG1 DNMT3A

5.76e-041965221118511
Pubmed

The repertoire of solute carriers of family 6: identification of new human and rodent genes.

SLC6A3 SLC6A11

7.06e-042165216125675
Pubmed

METTL3-mediated m6A modification is required for cerebellar development.

JAG1 METTL14

7.06e-042165229879109
Pubmed

Nonmuscle Myosin II Regulates the Morphogenesis of Metanephric Mesenchyme-Derived Immature Nephrons.

JAG1 ITGA8

7.06e-042165225168025
Pubmed

DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation.

JAG1 DNMT3A

7.76e-042265230518531
Pubmed

PRDM16 expression and function in mammalian cochlear development.

JAG1 ITGA8

8.48e-042365235451126
Pubmed

METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.

PRMT5 EIF3L PSMD1 METTL14

9.35e-0423165436597993
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

AREL1 ZFYVE26 DNAH9

9.92e-041046539205841
Pubmed

Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the Skin.

EDAR JAG1

1.00e-032565230220568
Pubmed

Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.

DNAI1 DYNC2H1

1.00e-032565227340223
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CEP350 GBF1 SASH1 PLEKHG3 N4BP2 PRMT5 PFKP

1.11e-0386165736931259
Pubmed

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.

PRMT5 EIF3L PSMD1 XPO1 PFKM

1.17e-0342265527342126
Pubmed

Deterministic and stochastic allele specific gene expression in single mouse blastomeres.

ATP11B JAG1 PFKP ZFX DNMT3A

1.19e-0342465521731673
Pubmed

Identification of FBXO25-interacting proteins using an integrated proteomics approach.

PRMT5 XPO1 PFKP

1.23e-0311265320473970
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

LY6G5B CEP350 PPP3CB CILP N4BP2 CUL9

1.24e-0363965623443559
Pubmed

TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma.

EIF3L XPO1

1.26e-032865229653964
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

CEP350 GBF1 EIF3L PFKP

1.27e-0325165429778605
Pubmed

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.

MGAM PFKM PFKP

1.29e-0311465328245920
Pubmed

Dynamic MAPK/ERK Activity Sustains Nephron Progenitors through Niche Regulation and Primes Precursors for Differentiation.

JAG1 ITGA8

1.35e-032965230220628
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

PRMT5 EIF3L CUL9 PSMD1 XPO1 PFKP

1.38e-0365365622586326
Pubmed

Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone.

PIK3C2G PFKM PFKP

1.39e-0311765318996102
Pubmed

Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation.

PRMT5 EIF3L PSMD1 XPO1

1.40e-0325865421081666
Pubmed

p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation.

EDAR JAG1

1.45e-033065216524929
Pubmed

USP14 is a deubiquitinase for Ku70 and critical determinant of non-homologous end joining repair in autophagy and PTEN-deficient cells.

PSMD1 XPO1

1.45e-033065231740976
Pubmed

Targeting the p300/NONO axis sensitizes melanoma cells to BRAF inhibitors.

PRMT5 PFKM

1.45e-033065234017080
Pubmed

C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.

EIF3L PSMD1 XPO1

1.46e-0311965335776542
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

GBF1 PPP3CB PRMT5 EIF3L PSMD1 XPO1 ERI1 PFKM PFKP

1.48e-03145565922863883
Pubmed

miR-218 Promotes Dopaminergic Differentiation and Controls Neuron Excitability and Neurotransmitter Release through the Regulation of a Synaptic-Related Genes Network.

SLC6A3 DNMT3A

1.54e-033165237816598
Pubmed

A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.

ERI1 DNAH9

1.65e-033265223049088
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

PRMT5 PSMD1 XPO1 PFKP

1.70e-0327265431010829
Pubmed

Distinct roles and regulations for HoxD genes in metanephric kidney development.

JAG1 ITGA8

1.75e-033365218159948
Pubmed

Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions.

CD28 XPO1

1.75e-033365216354571
Pubmed

Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.

CACNA2D1 LRP1B

1.75e-033365224159190
Pubmed

Genome-wide association study of smoking behaviours among Bangladeshi adults.

SASH1 TENM3

1.86e-033465224665060
Pubmed

Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development.

EDAR JAG1

1.86e-033465223123965
InteractionDEFB135 interactions

CACNA2D1 ITGA8 LRP1B CEMIP2

7.80e-0642614int:DEFB135
InteractionCLU interactions

CEBPB TENM3 PTPRS ITGA8 XPO1 LRP1B METTL14

8.99e-06245617int:CLU
Cytoband2p12

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

4.00e-101176672p12
CytobandEnsembl 112 genes in cytogenetic band chr2p11

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

2.59e-08213667chr2p11
Cytoband3p25.3

SLC6A11 SETD5

1.94e-03456623p25.3
GeneFamilyImmunoglobulin kappa locus at 2p11.2

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

4.94e-0983547351
GeneFamilyDyneins, axonemal

DNAI1 DNAH9

1.16e-0317542536
CoexpressionAtlasFacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#3

ZNF462 ATP11B GPR50 DYNC2H1 AASDH CEMIP2 ZFX

2.55e-05314597Facebase_RNAseq_e9.5_Mandibular Arch_2500_K3
ToppCell10x5'-GI_large-bowel|World / Manually curated celltypes from each tissue

IGKV1-16 IGKV1-5 IGKV1-6 ITGA8 IGKV1D-16 IGKV1D-8 IGKV4-1

5.78e-091686671290c909655bc37f6b8bf216d18127a21b99e9c0
ToppCellControl-Lymphoid-B_Plasma|Control / Disease state, Lineage and Cell class

IGKV1-16 IGKV1-5 ITGA8 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

6.80e-0917266761e33836b8cb0f347f3e699eb587a37073b6fa4c
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

1.35e-0819066779ee6d10dfbb775da149a1104da5823cf63bbb46
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

1.35e-0819066718762ce78ed0b206ade19e1c8ff76a2647489f68
ToppCell5'-Adult-LargeIntestine-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

1.40e-08191667d1d30279ed4612b4f62c225d9eabf0b8a7a09d11
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

1.51e-0819366734f6c13884fdf7f8a87f942fcb36a58cfac3f65d
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

1.56e-081946676ef4aeb8d8e35e4df58ff2a8256caa2113291de9
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NLRP11 IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-8 IGKV4-1

1.56e-08194667a4a70369541876e1192df8828b63e3d1746ae3d9
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

1.62e-08195667f3f7f1a77a1edd2b50a8211c76fe289738eb04cf
ToppCellBiopsy_IPF-Immune-Plasma_cells|Biopsy_IPF / Sample group, Lineage and Cell type

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

1.68e-08196667a1b6a8000b86efcb07843998aa3a49bb1f54bcda
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NLRP11 IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-16 IGKV1D-8 IGKV4-1

1.68e-08196667fec21383435779bf4c632decd3d29c6ca7baebfb
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

1.74e-081976679fe1b757f76c2d43d39aa9ac500eaba98723985c
ToppCell10x5'-blood-Lymphocytic_B_plasma-Plasma_cells|blood / Manually curated celltypes from each tissue

IGKV1-16 IGKV1-5 IGKV1-6 ITGA8 IGKV1D-43 IGKV4-1

8.49e-0814766658089378fac1743ce99dc4f1bd7b5253a927f050
ToppCell10x5'-blood-Lymphocytic_B_plasma|blood / Manually curated celltypes from each tissue

IGKV1-16 IGKV1-5 IGKV1-6 ITGA8 IGKV1D-43 IGKV4-1

9.57e-081506666bab0a8bf78ed7de9e1b67ede7496488f80f4863
ToppCell390C-Lymphocytic-Plasma_cell-|390C / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

1.21e-071566664f92ca30755430db44402afc603d1ecd8bfc3617
ToppCell390C-Lymphocytic-Plasma_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

1.21e-071566660de2fc695bd5f8d4633c514f71ea941c88137bac
ToppCellnormal_Lung-B_lymphocytes-MALT_B_cells|normal_Lung / Location, Cell class and cell subclass

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-8 IGKV4-1

1.35e-07159666fbd0131b66f4267f7b0d6c3ad874ad097b859074
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-8 LRP1B IGKV4-1

1.51e-07162666b46158e260bd2f35702cec73e3b035e8e9ec4469
ToppCellmetastatic_Brain-B_lymphocytes-Plasma_cells|metastatic_Brain / Location, Cell class and cell subclass

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-8 IGKV4-1

2.01e-0717066653634da9e9c72f6400639954c286c6e38ea5a188
ToppCellIPF-Lymphoid-B_Plasma|IPF / Disease state, Lineage and Cell class

IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

2.46e-07176666e4f33f6cd140dd4fa3002bcd65ac8005d27865d1
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-16 IGKV1D-8 IGKV4-1

2.54e-071776664c434a7b7cc54cf4dac996bbc3f5124d9ef9a9cd
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-16 IGKV1D-8 IGKV4-1

2.54e-07177666d746122bf8d208c3aa4d156e8c12d0a0e555c6e5
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-16 IGKV1D-8 IGKV4-1

2.54e-07177666fc40918825b7e1eb6861df59dfca944778a64b98
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-16 IGKV1D-8 IGKV4-1

2.72e-07179666837ed81f18257f444eaeadc4fac89deedd4e3061
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-16 IGKV1D-8 IGKV4-1

2.72e-07179666494febe77c6d4e6a2c6f0928bbf4c84b0301f188
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-16 IGKV1D-8 IGKV4-1

2.72e-07179666b6ee4f41d8fb5f047b7bdd8489dda0a89fc6d43f
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-Plasma_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV4-1

2.89e-07946654b6623de5a517ebf5df865e0dcd615111622ad3e
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-16 IGKV1D-8 IGKV4-1

3.74e-071896665a42be62552d912d0abf68f00d75ac80bbd69f2c
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B-B_plasma|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NLRP11 IGKV1-16 IGKV1-6 IGKV1D-43 IGKV1D-8 IGKV4-1

4.23e-07193666282b47dae6043eabb1e13d41d91c07b5ec21cd65
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-16 IGKV1D-8 IGKV4-1

4.49e-0719566613f4ee21568fd747608412d33559d10561dbb3c8
ToppCellBiopsy_Other_PF-Immune-Plasma_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-16 IGKV1D-8 IGKV4-1

4.49e-07195666d0305c6a68c9e361507b04db94f86873085d49b3
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_plasma|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-16 IGKV1D-8 IGKV4-1

4.63e-07196666c38e7f533c619afe008de0e99042f7180c2da918
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC6A3 SLC6A11 ATP13A5 LRP1B DNAH9

4.26e-06162665bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell356C-Fibroblasts-Fibroblast-D|356C / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-5 TENM3 ITGA8 ADAMTS8 MGAT4C

4.80e-061666657286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell390C-Lymphocytic-Plasma_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

4.80e-061666654ba3711a02d3695b27f7cefd7c60e3be009f5bef
ToppCell356C-Fibroblasts-Fibroblast-D-|356C / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-5 TENM3 ITGA8 ADAMTS8 MGAT4C

4.80e-061666657c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCell390C-Lymphocytic-Plasma_cell-|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

4.80e-0616666535f6ae2664935dda0d883b32a050ced843204f2d
ToppCellPlasma_cells|World / lung cells shred on cell class, cell subclass, sample id

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-8 IGKV4-1

5.86e-0617366552a387e2a4694af61a9223a4c2ecf4e6f762c064
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-16 IGKV1-6 IGKV1D-43 IGKV1D-8 IGKV4-1

5.86e-061736657e6bfe85f60834f317941b70d6e0dc3bd527d293
ToppCellHealthy-Plasmablast|World / disease group, cell group and cell class

IGKV1-16 IGKV1-5 IGKV1D-16 IGKV1D-8 IGKV4-1

6.03e-061746656becb456d8f44a1224c6d42be78d4c8cdb51f199
ToppCell3'_v3-bone_marrow-Lymphocytic_B_plasma-Plasma_cells|bone_marrow / Manually curated celltypes from each tissue

NLRP11 IGKV1-16 IGKV1-5 ITGA8 IGKV4-1

6.20e-0617566551301f3f44d3e88397f367cedd1e2abaa2be4c6f
ToppCellCOPD-Lymphoid-B_Plasma|World / Disease state, Lineage and Cell class

IGKV1-16 IGKV1-5 IGKV1D-16 IGKV1D-8 IGKV4-1

6.20e-06175665d73ee324479172501481b54967a0f3bd870fcf3a
ToppCellControl-Lymphoid_P-Plasmablast|Control / Disease group, lineage and cell class

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-16 IGKV4-1

6.37e-061766654b4416f342b732d2cc60133838728880326257d8
ToppCellControl-Lymphoid_P|Control / Disease group, lineage and cell class

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-16 IGKV4-1

6.37e-06176665d895a6b295cd649273ff80ad7785a3e0ae4c728a
ToppCell(2)_Plasma_cells|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

IGKV1-5 IGKV1-6 IGKV1D-16 IGKV1D-8 IGKV4-1

6.55e-06177665ed3c936bb69f9bc7291b4f6cde1d204078117c48
ToppCellHealthy-Plasmablast|Healthy / disease group, cell group and cell class

IGKV1-16 IGKV1-5 IGKV1D-16 IGKV1D-8 IGKV4-1

6.55e-061776654ff75c609ac9edf7a94bda42eb7124c559e8b6aa
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV4-1

7.11e-06180665cea079bc02e08c46600eed05ab9924ec90e1e3d3
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-43 IGKV4-1

7.30e-06181665e47664a264a2c37390d1668ce04eef2e0172f4cb
ToppCellMild_COVID-19-B_cell|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-8 IGKV4-1

7.70e-06183665dea119e2988e954475f557f0bbe12556a83e81a4
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-8 IGKV4-1

7.70e-06183665cf5c98f451a568308c52da5c926543dd4836c6b2
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-16 IGKV4-1

7.91e-0618466515f2c10101ccc8ed059520fc082ee42593dff269
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-16 IGKV4-1

7.91e-06184665a90a58d9e319afa1cd572e4c2f516fadc42f56e5
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-8 IGKV4-1

8.12e-061856650fff2608f507e019ebb69c27e58fd5be3b049bef
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-8 IGKV4-1

8.12e-0618566579edc1eeb7b5b9123961ac3ecf398ee68d9dddb9
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-5 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

8.12e-0618566508bc817908076734d66f2805cb954141f2cc5a18
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-5 IGKV1D-43 IGKV1D-16 IGKV1D-8 IGKV4-1

8.12e-061856651704a12153a9b107bf03ecccd1a036cf61334d7a
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgA_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

IGKV1-5 IGKV1-6 IGKV1D-43 IGKV1D-16 IGKV4-1

8.34e-06186665e2c050ba02e1f84f0b7258dc92e7ff6ab349ff67
ToppCellMild_COVID-19-B_cell-B_cell|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-8 IGKV4-1

8.34e-06186665855a5a00ba2aa1b5c63b8db56d026ddecc546050
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G DYNC2H1 B4GALNT3 PFKP LRP1B

8.55e-06187665f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G DYNC2H1 B4GALNT3 PFKP LRP1B

9.01e-06189665e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell(2)_Fibroblasts-(22)_Fibro-3|World / Cell class and subclass of bone marrow stroma cells in homeostatis

GREB1L CACNA2D1 TENM3 CILP ITGA8

9.24e-061906653aed03b87ba2c8d479048c3ceef3ff5e38746c28
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-lymphocytic-B_lymphocytic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IGKV1-16 IGKV1-5 IGKV1-6 IGKV1D-8 IGKV4-1

9.24e-06190665a21d0c574abf21e7cb865a21a48f29c92d055fbe
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GREB1L MGAM TENM3 PIK3C2G LRP1B

9.48e-061916653e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TENM3 PLEKHG3 JAG1 ITGA8 PFKP

9.48e-061916659431ffd6b758f756609d9057de2023596e22b5d4
ToppCellrenal_papilla_nuclei-Adult_normal_reference|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

GREB1L MGAM CACNA2D1 TENM3 ITGA8

9.72e-061926656c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-5 IGKV1-6 ITGA8 IGKV1D-8 IGKV4-1

9.72e-06192665ca4d8e540d9e6fa47ecf97648cbd5abfc7ab7f85
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GREB1L MGAM TENM3 PIK3C2G LRP1B

1.02e-0519466504bfc555743f7d8821439d05ae442d15e9886c59
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GREB1L MGAM TENM3 PIK3C2G LRP1B

1.02e-0519466569bff17df4a760ccf081cf52ff04af02c14f448d
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TENM3 NPAS3 ITGA8 LRP1B MGAT4C

1.02e-0519466585e00861c5068a27d0cf0ae677f420c8245baa9a
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

IGKV1-16 IGKV1-5 IGKV1D-16 IGKV1D-8 IGKV4-1

1.05e-051956652d18f08f33f3b261c77b8adf87d1a184cc6d7400
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A3 SLC6A11 ATP13A5 LRP1B

6.39e-0514566496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G DYNC2H1 B4GALNT3 LRP1B

7.86e-051536649b6675ace8a83c8d446b722301d0ec4e6840f3fc
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC41A2 DYNC2H1 JAG1 PFKP

7.86e-051536640ef7c45cdd854c79e527006034029767f8e108b2
ToppCellPBMC-Control-cDC_2|Control / Compartment, Disease Groups and Clusters

ZNF462 IGKV1-5 NBEAL1 IGKV4-1

7.86e-051536644ee37266b0054f276c7a73ab9220f681b9d74c71
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-MALT_B_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

IGKV1-16 IGKV1-5 IGKV1-6 IGKV4-1

9.13e-05159664204e5a675f4684c9570c24c8d34bbf632fd8164a
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3C2G ATP13A5 LRP1B DNAH9

9.35e-05160664c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3C2G ATP13A5 LRP1B DNAH9

9.35e-0516066425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell368C-Lymphocytic-Plasma_cell-|368C / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-5 IGKV1-6 IGKV1D-8 IGKV4-1

9.81e-05162664c21a54310b239d999bbc9d8fb5e8fda16e0bc336
ToppCell368C-Lymphocytic-Plasma_cell|368C / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-5 IGKV1-6 IGKV1D-8 IGKV4-1

9.81e-05162664f945688815229c8386cbcbf46deee7df316fa8d3
ToppCell343B-Lymphocytic-Plasma_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PTPRS ITGA8 IGKV1D-16 IGKV4-1

1.03e-04164664cf62d34ce9dd220fe61748466c84fd70d9ba697c
ToppCell343B-Lymphocytic-Plasma_cell-|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PTPRS ITGA8 IGKV1D-16 IGKV4-1

1.03e-04164664e00549bc8b3a5566f39031f39d7e698b0b107a7f
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

GREB1L CACNA2D1 NPAS3 MGAT4C

1.03e-04164664be49af6335f2505065cde2cb9800e4a5516811b1
ToppCell367C-Lymphocytic-Plasma_cell-|367C / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-5 IGKV1-6 IGKV1D-43 IGKV4-1

1.10e-04167664f2185eb72f0137136f6d71af2a70168fded6c940
ToppCell367C-Lymphocytic-Plasma_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

IGKV1-5 IGKV1-6 IGKV1D-43 IGKV4-1

1.10e-041676645e768cf24699893e05d1bcb1c92dba2336943a64
ToppCellBAL-Mild-Lymphocyte-B|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-16 IGKV1-5 IGKV1-6 IGKV4-1

1.15e-04169664307571e57c3bfdf15f0fe1a8b36585e8e4f8a207
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)|Children_(3_yrs) / Lineage, Cell type, age group and donor

GREB1L CACNA2D1 NPAS3 MGAT4C

1.15e-04169664b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3C2G ATP13A5 LRP1B DNAH9

1.15e-0416966412bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell-B_activate-7|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-16 IGKV1-5 IGKV1-6 IGKV4-1

1.18e-04170664ee2ee67d90ae4596de8ccd620e37c82cf51651d4
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-16 IGKV1-5 IGKV1-6 IGKV4-1

1.18e-04170664d7ca0c6ce5d2b7de99346f87e07aa7fe728fa08a
ToppCell-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

NLRP11 IGKV1-6 TRAV38-1 IGKV4-1

1.18e-04170664601630644f09133ee4c5e64499460b55cf3e80a0
ToppCellControl-Lymphoid-B_Plasma|World / Disease state, Lineage and Cell class

IGKV1-5 ITGA8 IGKV1D-43 IGKV4-1

1.18e-04170664fb05f49b7113470995b3c16683c54dc1a660b73a
ToppCellBAL-Mild-Lymphocyte-B-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGKV1-16 IGKV1-5 IGKV1-6 IGKV4-1

1.18e-0417066452787f6d529c285d9f0c04cc022710ead5b89b3f
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

CACNA2D1 PLEKHG3 JAG1 ITGA8

1.24e-04172664c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCell10x5'-Lung-Lymphocytic_B-Memory_B_cells|Lung / Manually curated celltypes from each tissue

IGKV1-16 IGKV1-6 IGKV1D-8 IGKV4-1

1.24e-041726642cb2dc7cfd6db5a98a393b1a84c23abf3d692a53
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGKV1-5 IGKV1-6 IGKV1D-16 IGKV4-1

1.26e-041736640ca2169a275404118038c0489a48062879488765
ToppCell10x5'-bone_marrow-Lymphocytic_B_plasma-Plasma_cells|bone_marrow / Manually curated celltypes from each tissue

IGKV1-5 IGKV1-6 ITGA8 IGKV4-1

1.26e-04173664300904fd35536a69be81d76fe33fe16544523ceb
ToppCell10x5'-bone_marrow-Lymphocytic_B_plasma|bone_marrow / Manually curated celltypes from each tissue

IGKV1-5 IGKV1-6 ITGA8 IGKV4-1

1.29e-04174664b1931028cf80af5eff6da15d7f0196205f17926f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TENM3 B4GALNT3 LRP1B CEMIP2

1.35e-041766640710689e66deba179b0a8038cdd56b4834984f12
ToppCellIPF-Lymphoid-B_Plasma|World / Disease state, Lineage and Cell class

IGKV1-5 IGKV1D-43 IGKV1D-8 IGKV4-1

1.35e-04176664cc0cab6487df6867b529596ec94f55d31aa6ca36
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IGKV1-16 IGKV1-5 IGKV1-6 IGKV4-1

1.38e-04177664c2b0fb5921eea24d248d6e6ccb57c29b0832602c
Diseaseasthma, response to diisocyanate

CACNA2D1 TENM3 DYNC2H1 MYLIP NPAS3 ITGA8 LRP1B

1.01e-06261607EFO_0006995, MONDO_0004979
Diseasewhite matter microstructure measurement

CACNA2D1 SASH1 NBEAL1 CD28 JAG1 PSMD1 ERI1

1.41e-05390607EFO_0005674
Diseaserenal agenesis (is_implicated_in)

GREB1L ITGA8

2.43e-054602DOID:14766 (is_implicated_in)
Diseaseglycogen storage disease (implicated_via_orthology)

PFKM PFKP

2.43e-054602DOID:2747 (implicated_via_orthology)
Diseasehepatocellular carcinoma (is_marker_for)

CEBPB JAG1 ANXA10 XPO1 LRP1B DNMT3A

3.38e-05301606DOID:684 (is_marker_for)
DiseaseCongenital absence of kidneys syndrome

GREB1L ITGA8

4.05e-055602C1609433
DiseasePeripheral T-Cell Lymphoma

CD28 DNMT3A

1.81e-0410602C0079774
DiseaseFacies

JAG1 DNMT3A

1.81e-0410602C0282631
Diseasethyroid stimulating hormone measurement

SASH1 PTPRS ITGA8 B4GALNT3 ERI1

5.08e-04323605EFO_0004748
Diseaseresponse to radiation, Urinary retention

PTPRS LRP1B

5.42e-0417602GO_0009314, HP_0000016
Diseasefeeling nervous measurement

MGAM CACNA2D1 AREL1

7.50e-0487603EFO_0009597
DiseaseHeadache, HbA1c measurement

NBEAL1 PFKM

8.33e-0421602EFO_0004541, HP_0002315
Diseasedisease of metabolism (implicated_via_orthology)

PFKM PFKP

8.33e-0421602DOID:0014667 (implicated_via_orthology)
DiseaseGranulomatous Slack Skin

CD28 DNMT3A

9.15e-0422602C0376407
DiseaseLymphoma, T-Cell, Cutaneous

CD28 DNMT3A

1.00e-0323602C0079773
Diseasecorpus callosum volume measurement

CACNA2D1 JAG1 XPO1

1.12e-03100603EFO_0010299
DiseaseSezary Syndrome

CD28 DNMT3A

1.38e-0327602C0036920
Diseaselumbar disc degeneration

DYNC2H1 PFKP

1.49e-0328602EFO_0004994
Diseasecysteine-rich with EGF-like domain protein 1 measurement

SLC6A11 SETD5

1.94e-0332602EFO_0021870

Protein segments in the cluster

PeptideGeneStartEntry
NFADSYYDYICIIDF

ERI1

121

Q8IV48
YCEVYQYSECFLANQ

ATP13A5

1001

Q4VNC0
YCLQYSNNLQEDIYS

ANXA10

131

Q9UJ72
AYDNAVNLSCKYSYN

CD28

31

P10747
YQYDDDGYQSYCTIC

DNMT3A

526

Q9Y6K1
KCFYQENAYYQDRFS

B4GALNT3

391

Q6L9W6
SFREQQCEKYNAYNY

ADAMTS8

586

Q9UP79
CFDECNNQLPVYYTY

AASDH

21

Q4L235
NQNTYDDIAQDFKYY

DNAI1

291

Q9UI46
IANNALYNSADYSYS

ARMCX4

2061

Q5H9R4
AAVEALNVFYYCSYE

NBEAL1

2231

Q6ZS30
YQLINVYCNSFYADF

PIK3C2G

491

O75747
YLWFYRFYCNNENCS

PIK3C2G

676

O75747
YAFLLNFCANTSDYY

MGAT4C

206

Q9UBM8
VFEDYLYATNSDNYN

LRP1B

421

Q9NZR2
YDSTSYYSANNLNVF

NLRP11

136

P59045
EQRFESYYNYCNLFN

EIF3L

151

Q9Y262
SYYNYCNLFNYILNA

EIF3L

156

Q9Y262
QPEDFATYYCQQYYS

IGKV1D-43

101

A0A0B4J1Z2
NSNYNAETYASYFSA

METTL14

366

Q9HCE5
CYFVNDLYSVSDVQY

MGAM

996

O43451
AEYSNCGENEYYNQT

EDAR

26

Q9UNE0
QSEDFATYYCQQYYS

IGKV1D-8

101

A0A087WSZ0
YLAAYFIAYFNSCLN

GPR50

276

Q13585
CNENYTTDFIFNLYS

PFKM

631

P08237
CSENYTTDFIYQLYS

PFKP

641

Q01813
YNQNTAKYNYEELCA

MYLIP

131

Q8WY64
TQNVQYDFNRYFCED

GREB1L

1701

Q9C091
CYVAIQNFSAYAEFS

ITGA8

171

P53708
EDEYQFCYQAALEYL

PTPRS

1926

Q13332
DSEFQYTYEYQGNAS

DYNC2H1

1646

Q8NCM8
VYAFNKSYDYQSVCE

CACNA2D1

891

P54289
VANFYYEADCLAAAY

CEBPB

26

P17676
DCYSDERYQCYNQEQ

CEP350

2581

Q5VT06
YFEAYLYNATNCSST

AREL1

296

O15033
EFCSYLQYLEYLSQN

PRMT5

276

O14744
SCYAENQCQFFDYDT

CEMIP2

501

Q9UHN6
AAAGQSYSYYCDQNF

CFHR4

46

Q92496
NTYFAEYWYQAQCCQ

LY6G5B

86

Q8NDX9
TELYINYDCDYYCSN

GBF1

536

Q92538
NYDCDYYCSNLFEEL

GBF1

541

Q92538
QPDDFATYYCQQYNS

IGKV1-5

101

P01602
QPEDFATYYCLQDYN

IGKV1-6

101

A0A0C4DH72
QPEDFATYYCQQYNS

IGKV1-16

101

P04430
AEDVAVYYCQQYYST

IGKV4-1

106

P06312
LAYACVYSFYSQDAE

CUL9

2346

Q8IWT3
CDAQFLYSYEYLGNT

DNAH9

1826

Q9NYC9
SYFYNYPAVCEFLQN

PPP3CB

266

P16298
DSYYQDNCANITFTF

JAG1

951

P78504
MFDSSQYPYNCFNYD

FOXL3

1

A0A1W2PRP0
DYSYNQFSTYGDANA

PRCC

341

Q92733
EFDIYTQYCNNYPNS

PLEKHG3

176

A1L390
YQICFDLYESASQQF

PSMD1

246

Q99460
TIAFDYEYSNCNYKV

SETD5

386

Q9C0A6
ASSSCSQKYDDYANY

SLC41A2

101

Q96JW4
SQKYDDYANYNYCDG

SLC41A2

106

Q96JW4
YDGIYCESTYQNLQA

NPAS3

36

Q8IXF0
DCFQNATNSFYYDVG

CILP

416

O75339
YQFYCLFSQQTLYDS

ATP11B

896

Q9Y2G3
QEEAAAQSFYQTYFC

XPO1

906

O14980
AFSSYNKFTNNCYRD

SLC6A3

331

Q01959
DLAQQYADYYNTCFS

SASH1

61

O94885
GSYNNYNNNCYRDCI

SLC6A11

321

P48066
YLYNFSYSNDNDITA

TENM3

1541

Q9P273
YQCQYCEYRSADSSN

ZFX

576

P17010
CYIDYTNFEDLQQHY

ZNF462

891

Q96JM2
NNTYYQECLFYLHNY

ZFYVE26

2156

Q68DK2
LSCTYDTSENNYYLF

TRAV38-1

41

A0A0B4J264
QPEDFATYYCQQYNS

IGKV1D-16

101

P01601
STDDYFYINGQYQFD

N4BP2

471

Q86UW6