Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentcyclin-dependent protein kinase holoenzyme complex

CCNB3 CCNB1

2.04e-0361232GO:0000307
GeneOntologyCellularComponentdendritic shaft

LZTS1 PREX1

2.98e-0374232GO:0043198
DomainCyclin_C-dom

CCNB3 CCNB1

1.95e-0417232IPR004367
DomainCyclin_C

CCNB3 CCNB1

1.95e-0417232PF02984
DomainCyclin_C

CCNB3 CCNB1

1.95e-0417232SM01332
DomainPWWP

NSD2 HDGFL3

2.72e-0420232SM00293
DomainPWWP

NSD2 HDGFL3

3.61e-0423232PF00855
DomainPWWP_dom

NSD2 HDGFL3

3.61e-0423232IPR000313
DomainPWWP

NSD2 HDGFL3

3.94e-0424232PS50812
DomainCYCLINS

CCNB3 CCNB1

5.38e-0428232PS00292
DomainCyclin_N

CCNB3 CCNB1

7.48e-0433232IPR006671
DomainCyclin_N

CCNB3 CCNB1

7.48e-0433232PF00134
DomainCYCLIN

CCNB3 CCNB1

9.93e-0438232SM00385
Domain-

CCNB3 CCNB1

1.10e-03402321.10.472.10
DomainCyclin-like

CCNB3 CCNB1

1.27e-0343232IPR013763
DomainZinc_finger_PHD-type_CS

NSD2 MLLT10

2.88e-0365232IPR019786
DomainPHD

NSD2 MLLT10

3.81e-0375232PF00628
DomainZnf_PHD-finger

NSD2 MLLT10

4.22e-0379232IPR019787
DomainPH

PLEKHO1 PREX1 PLCH1

4.63e-03278233SM00233
DomainPH_DOMAIN

PLEKHO1 PREX1 PLCH1

4.68e-03279233PS50003
DomainPH_domain

PLEKHO1 PREX1 PLCH1

4.73e-03280233IPR001849
DomainPHD

NSD2 MLLT10

5.32e-0389232SM00249
DomainZnf_PHD

NSD2 MLLT10

5.56e-0391232IPR001965
DomainZF_PHD_2

NSD2 MLLT10

6.04e-0395232PS50016
DomainZF_PHD_1

NSD2 MLLT10

6.17e-0396232PS01359
Domainzf-C2H2_6

ZNF770 MYNN ZNF85

6.50e-03314233PF13912
Domain-

PLEKHO1 PREX1 PLCH1

1.18e-023912332.30.29.30
DomainZnf_FYVE_PHD

NSD2 MLLT10

1.40e-02147232IPR011011
DomainPH_dom-like

PLEKHO1 PREX1 PLCH1

1.49e-02426233IPR011993
Domain-

NSD2 MLLT10 SH3RF1

1.71e-024492333.30.40.10
DomainZnf_RING/FYVE/PHD

NSD2 MLLT10 SH3RF1

1.81e-02459233IPR013083
PathwayKEGG_MEDICUS_PATHOGEN_HIV_VPR_TO_WEE1_CELL_CYCLE_G2M

CCNB3 CCNB1

7.84e-065132M49022
PathwayKEGG_MEDICUS_REFERENCE_WEE1_CELL_CYCLE_G2_M

CCNB3 CCNB1

1.64e-057132M47574
PathwayKEGG_MEDICUS_REFERENCE_ATR_P21_CELL_CYCLE_G2_M

CCNB3 CCNB1

2.82e-059132M47586
PathwayKEGG_MEDICUS_REFERENCE_CDC25_CELL_CYCLE_G2_M

CCNB3 CCNB1

3.52e-0510132M47572
PathwayKEGG_MEDICUS_PATHOGEN_HIV_VPR_TO_CDC25_CELL_CYCLE_G2M

CCNB3 CCNB1

4.30e-0511132M47573
PathwayWP_P53_SIGNALING

CCNB3 CCNB1

1.58e-0365132MM15852
PathwayKEGG_P53_SIGNALING_PATHWAY

CCNB3 CCNB1

1.73e-0368132M6370
PathwayWP_DNA_DAMAGE_RESPONSE

CCNB3 CCNB1

1.78e-0369132M39339
PathwayREACTOME_G2_M_DNA_DAMAGE_CHECKPOINT

NSD2 CCNB1

1.93e-0372132MM15381
Pubmed

Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity.

CCNB3 CCNB1

4.56e-0652427474080
Pubmed

Cell cycle G2 arrest induced by HIV-1 Vpr in fission yeast (Schizosaccharomyces pombe) is independent of cell death and early genes in the DNA damage checkpoint.

CCNB3 CCNB1

4.56e-06524210958988
Pubmed

Hypophosphorylation of poly(A) polymerase and increased polyadenylation activity are associated with human immunodeficiency virus type 1 Vpr expression.

CCNB3 CCNB1

4.56e-06524211878934
Pubmed

The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle.

CCNB3 CCNB1

4.56e-0652427666531
Pubmed

Human immunodeficiency virus type 1 vpr gene induces phenotypic effects similar to those of the DNA alkylating agent, nitrogen mustard.

CCNB3 CCNB1

4.56e-0652429094673
Pubmed

Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B.

CCNB3 CCNB1

6.83e-0662427474100
Pubmed

HIV-1 Vpr interacts with a human 34-kDa mov34 homologue, a cellular factor linked to the G2/M phase transition of the mammalian cell cycle.

CCNB3 CCNB1

9.56e-0672429520381
Pubmed

HIV transcriptional activation by the accessory protein, VPR, is mediated by the p300 co-activator.

CCNB3 CCNB1

9.56e-0672429560267
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ALMS1 PREX1 SLC7A14 SH3RF1 PLCH1

1.91e-0549324515368895
Pubmed

Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr.

CCNB3 CCNB1

3.00e-05122427494303
Pubmed

A PWWP Domain of Histone-Lysine N-Methyltransferase NSD2 Binds to Dimethylated Lys-36 of Histone H3 and Regulates NSD2 Function at Chromatin.

NSD2 HDGFL3

4.13e-051424226912663
Pubmed

HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25.

CCNB3 CCNB1

1.47e-042624211531413
Pubmed

Effects of Pparγ1 deletion on late-stage murine embryogenesis and cells that undergo endocycle.

CCNB3 CCNB1

1.83e-042924234246625
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

NSD2 HDGFL3 MLLT10 PLCH1

4.54e-0453324430554943
Pubmed

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.

TICRR PREX1 CCNB1

5.02e-0422724326410627
Pubmed

Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.

MYNN ZNF85

5.26e-04492429630514
Cytoband3q26.2

SLC7A14 MYNN

9.12e-05272423q26.2
CytobandEnsembl 112 genes in cytogenetic band chr13q33

ARGLU1 CCDC168

3.82e-0455242chr13q33
CytobandEnsembl 112 genes in cytogenetic band chr3q26

SLC7A14 MYNN

5.68e-03216242chr3q26
GeneFamilyCyclins

CCNB3 CCNB1

2.74e-0428162473
GeneFamilyPHD finger proteins

NSD2 MLLT10

2.81e-039016288
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHO1 PREX1

1.40e-02206162682
GeneFamilyEF-hand domain containing

EFCAB13 PLCH1

1.57e-02219162863
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF770 MYNN ZNF85

2.37e-0271816328
CoexpressionLAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_SMALL_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP

ALMS1 TMTC4 NSD2 TICRR SLC7A14 CCNB1

2.69e-05680246MM456
CoexpressionTOYOTA_TARGETS_OF_MIR34B_AND_MIR34C

ALMS1 NSD2 TICRR ZNF85 CCNB1

4.94e-05454245M19927
CoexpressionAtlaskidney_e10.5_UretericTip_HoxB7_k-means-cluster#2_top-relative-expression-ranked_500

ALMS1 TICRR CCNB1 PLCH1

1.69e-05139244gudmap_kidney_e10.5_UretericTip_HoxB7_k2_500
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

ALMS1 PLEKHO1 ARGLU1 NSD2 TICRR SYCP2L ZNF770 HDGFL3 CCNB1

1.69e-051459249facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

ALMS1 PLEKHO1 ARGLU1 JHY CCNB1 MLLT10

2.20e-05532246Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

ALMS1 PLEKHO1 ARGLU1 NSD2 TICRR ZNF770 HDGFL3 CCNB1

4.62e-051257248facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

ALMS1 PLEKHO1 ARGLU1 PREX1 JHY

1.55e-04469245Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#1_top-relative-expression-ranked_100

CCNB3 TEX15

2.07e-0419242gudmap_developingGonad_e18.5_ovary_100_k1
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K3

ALMS1 PLEKHO1 ARGLU1 TICRR PREX1 ZNF770 HDGFL3

3.47e-041252247facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_1000

ALMS1 TICRR CCNB1 PLCH1

4.04e-04316244gudmap_kidney_P3_CapMes_Crym_k4_1000
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#4_top-relative-expression-ranked_100

CCNB3 TEX15

4.88e-0429242gudmap_developingGonad_e16.5_ovary_100_k4
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#3_top-relative-expression-ranked_200

CCNB3 TEX15

5.58e-0431242gudmap_developingGonad_e14.5_ ovary_200_k3
CoexpressionAtlaskidney_e10.5_UretericTip_HoxB7_k-means-cluster#4_top-relative-expression-ranked_1000

ALMS1 TICRR CCNB1 PLCH1

5.81e-04348244gudmap_kidney_e10.5_UretericTip_HoxB7_k4_1000
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TICRR TEX15 CCNB1

4.99e-051342434d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NSD2 TICRR CCNB1

8.15e-05158243d72d6527dc50207ddbada262460d3c4bac249a19
ToppCellcontrol-Myeloid-pDC|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SYCP2L CCDC168 JHY

9.77e-05168243affc39c7568b7df4b36af6f5b0e3702a18b6268c
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMTC4 SH3RF1 PLCH1

9.77e-05168243d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NSD2 TICRR CCNB1

1.08e-0417424384da9faff088d05233183b425385beb054c92d1b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NSD2 TICRR CCNB1

1.08e-04174243dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NSD2 TICRR CCNB1

1.10e-04175243876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCellControl-Developping_Plasmablast|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

NSD2 TICRR CCNB1

1.18e-041792439383568f78b07b8cca72ece5d15fea209aa54ea9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NSD2 TICRR CCNB1

1.20e-04180243401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell3'_v3-bone_marrow-Hematopoietic_Erythro-Mega-Erythrocytic-Meg|bone_marrow / Manually curated celltypes from each tissue

TEX15 CCNB1 PLCH1

1.20e-0418024344ba37bead1ac39bce4d3eef00961063c50ced0d
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NSD2 TICRR CCNB1

1.28e-041842431edefa2a049d7e22d0bdb1ea3d7ef1c8d6ae0fe3
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-Proliferating_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NSD2 TICRR CCNB1

1.28e-041842438578c50eaa8ce1cefc0228185c66c8e25f4bfc32
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

NSD2 TICRR CCNB1

1.30e-041852439766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NSD2 TICRR CCNB1

1.30e-0418524330e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellfacs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TICRR CCNB1 PLCH1

1.32e-041862439feef5936985e936b3d88f9d1bb012abb6468570
ToppCellfacs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TICRR CCNB1 PLCH1

1.32e-0418624389f5b06bc56674af304912d481ac697c7c870904
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NSD2 TICRR CCNB1

1.34e-04187243cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NSD2 TICRR CCNB1

1.34e-04187243057569c9437219ecc396aa6e673b1178a2273837
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NSD2 TICRR CCNB1

1.34e-04187243e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NSD2 TICRR CCNB1

1.34e-041872439351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TICRR CCDC168 CCNB1

1.36e-04188243319fbeca200ab998daf49fcaee0bfdb57bf7ee4b
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NSD2 TICRR CCNB1

1.38e-041892431e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LZTS1 NSD2 CCNB1

1.41e-04190243b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSD2 TICRR CCNB1

1.43e-04191243239300ff76f2c855b2b04d3002461158be90a01b
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

NSD2 TICRR CCNB1

1.47e-041932434b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NSD2 TICRR CCNB1

1.49e-04194243f39a471293ecc5c5967b00e772b8f48ebc9affbe
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NSD2 TICRR CCNB1

1.49e-04194243a75ecd0b0a928d4646602f7d16a645f6b3df3af5
ToppCellControl-Lymphoid_T/NK-T/NK_proliferative|Control / Disease group, lineage and cell class

NSD2 TICRR CCNB1

1.49e-041942439bbb124001fba7450f4639f47f9b720a483e7242
ToppCellcontrol-Lymphocytic-Prol._cells|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NSD2 TICRR CCNB1

1.49e-041942434c76508de3291c952386caffda2d559629ba5998
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

NSD2 TICRR CCNB1

1.49e-04194243e14f66f7584909621b776292fbd52808273fd2ee
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TICRR CCNB1 PLCH1

1.49e-04194243c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCellPBMC-Control-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NSD2 TICRR CCNB1

1.49e-0419424317744fd6645cf5a447a01a83f07e8d305c2bcd9c
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

NSD2 TICRR CCNB1

1.52e-04195243764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCellDividing_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

NSD2 TICRR CCNB1

1.52e-0419524379ee423df85aa1631b7bdea74eacaf826dfc4a2c
ToppCellDividing_cells-Dividing_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

NSD2 TICRR CCNB1

1.52e-0419524319829760dfcc0edafd2a2bd80f424a45d039af1f
ToppCellcontrol-Lymphocytic-Prol._cells|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NSD2 TICRR CCNB1

1.54e-04196243886f7c865b086d6ebb4a1746865c30af6bbed345
ToppCell10x5'-blood-Lymphocytic_T_CD4/8-lo|blood / Manually curated celltypes from each tissue

NSD2 TICRR CCNB1

1.56e-04197243acd678586aa0e4375bc8fbcdaa1a796c8dd23885
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic-lymphocyte-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NSD2 TICRR CCNB1

1.56e-0419724321861d8b389fafbdb7c3499684c9b6deee3dbd5e
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

NSD2 TICRR CCNB1

1.56e-04197243434a5686a103bb766e0d80038413f0e12ea3981a
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NSD2 TICRR CCNB1

1.56e-041972434b13335a43b9d6abc8e542e72440da7feb82fbe6
ToppCellMild_COVID-19-T/NK-proliferating_T/NK|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

NSD2 TICRR CCNB1

1.56e-041972435fd52fba2cb6fa67377f873da2ff6ce9c83b0591
ToppCellMild-Lymphoid-T-Proliferating_T|Mild / Condition, Lineage, Cell class and cell subclass

NSD2 TICRR CCNB1

1.56e-04197243794517c70089da109f4c6489fe406c0ba6882b76
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

NSD2 TICRR CCNB1

1.56e-041972436bddfa199ca812d9e518eaa02c3d4fb67e9f5b16
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NSD2 TICRR CCNB1

1.56e-04197243c0a71a9452febda433bc544e4ac0a79c43dcf13e
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NSD2 TICRR CCNB1

1.56e-04197243d7a9296092153cf66426911fecd810f0c1ef978e
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NSD2 TICRR CCNB1

1.56e-04197243dcff23240bb7cb652d7426b29355aa74442ef6fc
ToppCellBAL-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NSD2 TICRR CCNB1

1.56e-04197243f34b1e34f1f0694564031077172c890b233ce8b7
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / Treatment groups by lineage, cell group, cell type

CCNB3 NSD2 CCNB1

1.56e-04197243038fd92750257d43d5e980fd06d77742b543f11a
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic-lymphocyte|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

NSD2 TICRR CCNB1

1.56e-04197243ffb004c37cdd26cb7cdcd80f769a2eded65416dc
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_NK-Cycling_NK|lymph-node_spleen / Manually curated celltypes from each tissue

NSD2 TICRR CCNB1

1.59e-04198243b2868a897dd96494cf1829c30e0ce508f52efdf3
ToppCell356C-Myeloid-Dendritic-cDC_proliferating_1|356C / Donor, Lineage, Cell class and subclass (all cells)

PLEKHO1 TICRR CCNB1

1.59e-04198243f801157468e59b5d049f703feadc9bb0f11e85cc
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NSD2 HDGFL3 CCNB1

1.59e-0419824336897e17de2e22ee6b23920ee6e60931903f3e5c
ToppCellsevere-Lymphocytic-Prol._cells|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NSD2 TICRR CCNB1

1.59e-041982434d8591eabb543ed789f963b507a07c560c76a7c9
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

TMTC4 ZNF85 MLLT10

1.61e-04199243fd1d1b95e01719e3d0a17d9d1f29717a47209d32
ToppCellVE-cycling|VE / Condition, Cell_class and T cell subcluster

NSD2 TICRR CCNB1

1.61e-0419924347c47ebc318a0b98841ca2656837bbd068899559
ToppCellLPS_anti-TNF-Endothelial-Endothelial-FOXM1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NSD2 TICRR CCNB1

1.61e-0419924398575fcce726589e93fbb4df1aab03e57cb56076
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NSD2 TICRR CCNB1

1.61e-04199243be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

TMTC4 ZNF85 MLLT10

1.61e-0419924391882af9dc7265c9b419f4415cbcf656087a2ab3
ToppCellVE-cycling-|VE / Condition, Cell_class and T cell subcluster

NSD2 TICRR CCNB1

1.61e-04199243c0a67149a19b65b3069dbc5261d81f658e6e39a2
ToppCellhealthy_donor-Lymphocytic-Proliferative_Lymphocyte|healthy_donor / Disease condition, Lineage, Cell class and subclass

NSD2 TICRR CCNB1

1.63e-04200243e4eb915c29909cf8535a3603c68976545c05e54b
ToppCellhealthy_donor-Lymphocytic-Proliferative_Lymphocyte-|healthy_donor / Disease condition, Lineage, Cell class and subclass

NSD2 TICRR CCNB1

1.63e-04200243415e7556b5ac45688e2c6c30a52bd40e0eb27c7d
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NSD2 TICRR CCNB1

1.63e-042002434cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells|GW12 / Sample Type, Dataset, Time_group, and Cell type.

TICRR CCNB1 SH3RF1

1.63e-042002430bba93f1271dac704dddcdea8cb0f84a7ac6f42a
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

NSD2 TICRR CCNB1

1.63e-042002439bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells-Neuroepithelial_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

TICRR CCNB1 SH3RF1

1.63e-04200243c9479452ab8c51139522383f745f02171ebbd7e2
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMTC4 LZTS1

3.56e-0452242d654e2b77c53ed5319015598b68a20bf4416380c
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Crim1_(Neuron.Gad1Gad2.Cplx3-Crim1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CCDC168 JHY

5.06e-046224291c49ae176d2a418a58398e9d5e55c77187cc2fb
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Crim1_(Neuron.Gad1Gad2.Cplx3-Crim1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CCDC168 JHY

5.06e-04622423275775572a65460b6248ee72b4c85e4d4dee424
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Tuba1c))|Striatum / BrainAtlas - Mouse McCarroll V32

TICRR CCNB1

1.33e-031012420b32e6071f05dbe808e51e18c3a3f8221f438f83
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)|Thalamus / BrainAtlas - Mouse McCarroll V32

CCNB3 MYNN

1.52e-0310824263d45cc3ee149a7baf255b70409f8ea54c56157b
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P3-Tnr|Thalamus / BrainAtlas - Mouse McCarroll V32

CCNB3 MYNN

1.52e-03108242d57eeda825b6e0e64bae185896ae7eea6a2a50e9
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P3|Thalamus / BrainAtlas - Mouse McCarroll V32

CCNB3 MYNN

1.52e-03108242db8472616886c6195f8c27c00f00133a9c10691d
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-|Thalamus / BrainAtlas - Mouse McCarroll V32

CCNB3 MYNN

1.52e-03108242c2aa6bf8554bfb6b0f9c5f6658601c6cf7c8bdbc
ToppCell(05)_Ciliated-(3)_72hpi|(05)_Ciliated / shred by cell type and Timepoint

PREX1 CCNB1

1.66e-03113242eaa5bc8f8183b353ee1e7618e99220eb3684cd60
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE|Cerebellum / BrainAtlas - Mouse McCarroll V32

TEX15 KCNU1

1.72e-0311524215b2c11225802cc15c01165d84a755432f02d82f
ToppCellControl-Developping_Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

NSD2 TICRR

1.87e-03120242695dab6b01ad2c33cdcaf92bb9996ff2899ef77e
ToppCellCOVID-19_Mild-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

CCDC168 PLCH1

2.00e-031242425ef9eb806fb2c8ee5aae0a75503d244b08ee10d4
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CCDC168 PLCH1

2.06e-0312624284dce108561d4b745d19250c2ac0667d9e4ea17d
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Hist1h2al)|Hippocampus / BrainAtlas - Mouse McCarroll V32

TICRR CCNB1

2.06e-031262426072996987f7b05949adb86c9433e3302c4441d2
ToppCellLPS-antiTNF-Unknown|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LZTS1 CCNB1

2.16e-03129242739b263296c28554967362060b154f7a95e1341d
ToppCellIonocyte-iono-4|World / Class top

MYNN TEX15

2.16e-0312924285ee6e16959cb58a58f5b09edf1f78d9ce6a9441
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Ccnb1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TICRR CCNB1

2.16e-03129242ff74d159034a09f7b174da18bfb9a26936252b4c
ToppCellLPS-antiTNF-Unknown-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LZTS1 CCNB1

2.19e-03130242615c233c7c2600c1c2bc5cf5b1c501fc474564ef
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYCP2L TEX15

2.19e-0313024292913960e4367261ba08a405b61a421bc5e18169
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Cdc20)|Hippocampus / BrainAtlas - Mouse McCarroll V32

TICRR CCNB1

2.23e-03131242f9fb8d74ca720b81fd5910cc975510359a8ef751
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LZTS1 TICRR

2.26e-0313224202491930097b75aaeedab9e8200711b0dc610944
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Proliferative_AT1_Progenitor|E16.5-samps / Age Group, Lineage, Cell class and subclass

JHY KCNU1

2.29e-03133242b0d3ac5abd9ebd490db46a3ef2e4ae88c4bf4e34
ToppCellRA-15._Ventricular_Cardiomyocyte_III|RA / Chamber and Cluster_Paper

CCNB3 KCNU1

2.33e-0313424260ee3accc54108e5b9a0018f6aa8488dc39d5ade
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

SYCP2L CCDC168

2.36e-031352423351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-7|TCGA-Brain / Sample_Type by Project: Shred V9

NSD2 TICRR

2.40e-03136242d94f0fbeb7b80d4cf0687d1924ebf8f9dd07358c
ToppCellRA-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

CCNB3 KCNU1

2.47e-031382425a713f24f633de463ef47ca37fbb2bb60c7fdb77
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNB3 TEX15

2.57e-031412424aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNB3 TEX15

2.57e-03141242e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CCDC168 TEX15

2.61e-03142242f720f13b339589fa924a42e89393e5db0b26300b
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNB3 TEX15

2.61e-03142242759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TICRR CCNB1

2.61e-03142242be63c48794a227ea55978524c0f5935342fc455e
ToppCellMS-CD8-exh_CD4|MS / Condition, Cell_class and T cell subcluster

CCNB3 LZTS1

2.61e-031422427591491520a883bb09fa2b8d0a20ae2abd2b8703
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PREX1 KCNU1

2.64e-031432424a0f26eef935fe68a1da5d319503059a8a8682dd
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PREX1 KCNU1

2.64e-0314324265328a0a2f3972fac596e07933e74b2ef7cceb84
ToppCellIIF-Lymphocyte-T_NK-dnT|IIF / Disease, Lineage and Cell Type

TMTC4 JHY

2.75e-03146242d0f361662db5f7be26104346e8431f7e30c5ce3a
DrugPyrazolopyridazine 1a

CCNB3 CCNB1

1.06e-055242CID006263849
DrugTranexamic acid [1197-18-8]; Up 200; 25.4uM; PC3; HT_HG-U133A

NSD2 JHY MLLT10 PLCH1

4.85e-051952442085_UP
DrugFluoxetine hydrochloride [59333-67-4]; Down 200; 11.6uM; PC3; HT_HG-U133A

PLEKHO1 NSD2 MLLT10 PLCH1

4.95e-051962446757_DN
DrugAmphotericin B [1397-89-3]; Up 200; 4.4uM; HL60; HT_HG-U133A

PLEKHO1 TEX15 HDGFL3 PLCH1

4.95e-051962442441_UP
DrugChlorprothixene hydrochloride [6469-93-8]; Down 200; 11.4uM; PC3; HT_HG-U133A

ALMS1 ZNF85 MLLT10 PLCH1

4.95e-051962446692_DN
DrugSulfadiazine [68-35-9]; Up 200; 16uM; PC3; HT_HG-U133A

PLEKHO1 NSD2 HDGFL3 PLCH1

4.95e-051962441810_UP
DrugGR63799

CCNB3 CCNB1

6.98e-0512242CID005311224
Drugaloisine A

CCNB3 CCNB1

8.25e-0513242CID005326843
Diseasemultiple myeloma

TICRR PREX1 MYNN

1.02e-04112243EFO_0001378
Diseaseinsomnia measurement

ALMS1 TEX15 MLLT10 PLCH1

4.20e-04443244EFO_0007876
Diseasepreeclampsia

LZTS1 PREX1

1.83e-0378242EFO_0000668
Diseasesleep duration

JHY MLLT10 SH3RF1

3.06e-03362243EFO_0005271
Diseaseinterleukin-6 measurement

LZTS1 EFCAB13

3.73e-03112242EFO_0004810
Diseaselifestyle measurement, maximum cigarettes per day measurement

LZTS1 KCNU1

4.41e-03122242EFO_0009264, EFO_0010724
Diseaseemphysema imaging measurement

NSD2 ZNF770

6.25e-03146242EFO_0007626
Diseasecervical carcinoma

ALMS1 LZTS1

9.55e-03182242EFO_0001061
Diseasediet measurement

ZNF770 TEX15 MLLT10 SH3RF1

9.56e-031049244EFO_0008111

Protein segments in the cluster

PeptideGeneStartEntry
RSKHTKSSKHNKKRS

ARGLU1

11

Q9NWB6
KKRFKSLEKSHKNTG

ALMS1

3676

Q8TCU4
HKLSSLKKKCTIYGK

CCNB3

281

Q8WWL7
KKSTSHGKVFFLKKQ

CCNB3

751

Q8WWL7
SQYKLRKSSHLKKLN

LZTS1

21

Q9Y250
HKKRSSSKNTKLKGY

JHY

636

Q6NUN7
LHSYTKLKGQKKSAR

NSD2

246

O96028
NSYTDIKNLKKHKTK

MYNN

506

Q9NPC7
TLKRTGKSKYKFRNH

KCNU1

701

A8MYU2
KAGSKRKKSYTSKKS

HDGFL3

141

Q9Y3E1
KNKYATSKHAKISTL

CCNB1

401

P14635
SGTINHKKYIKFSKT

EFCAB13

31

Q8IY85
STRKHRKKCKSYLKT

CCDC168

2316

Q8NDH2
SHKSRKYRSSSKMKS

CCDC168

6861

Q8NDH2
KKSTKRTKSINGSLY

PREX1

311

Q8TCU6
LRKSKSRSKKNHSKF

PLEKHO1

81

Q53GL0
KHSDTKKNTKKRHSF

SH3RF1

291

Q7Z6J0
YHFSKLKKSKRGSNR

MLLT10

196

P55197
GRTSSKAKSKSKHKQ

SLC7A14

741

Q8TBB6
TFGFGALSKHTKKKK

TMTC4

426

Q5T4D3
NFKKNKGYHKLLTKS

TICRR

951

Q7Z2Z1
SNQKKKSLKSYSSRK

SYCP2L

521

Q5T4T6
NFGKHKKTTKSRSKS

PLCH1

551

Q4KWH8
KHGTYKTIGNRKKKT

ZNF770

391

Q6IQ21
GKAFNQSSKLTKHKK

ZNF85

516

Q03923
KHKSYKTSGEKKCLS

TEX15

1091

Q9BXT5