Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainNIPSNAP

NIPSNAP3A NIPSNAP3B

3.71e-054472IPR012577
DomainNIPSNAP

NIPSNAP3A NIPSNAP3B

3.71e-054472PF07978
DomainDimeric_a/b-barrel

NIPSNAP3A NIPSNAP3B

1.29e-047472IPR011008
DomainDUF4599

SPATA31D4 SPATA31D3

4.03e-0412472PF15371
DomainDUF4599

SPATA31D4 SPATA31D3

4.03e-0412472IPR027970
Domainfn3

PTPRB TNN L1CAM

7.86e-03162473PF00041
DomainFN3

PTPRB TNN L1CAM

1.13e-02185473SM00060
Pubmed

Expression pattern and raft association of NIPSNAP3 and NIPSNAP4, highly homologous proteins encoded by genes in close proximity to the ATP-binding cassette transporter A1.

NIPSNAP3A NIPSNAP3B

1.87e-06248215177564
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

PRICKLE2 SPATA31D4 VIL1 SPATA31D3 TET3

1.75e-0523348537704626
Pubmed

Phosphacan short isoform, a novel non-proteoglycan variant of phosphacan/receptor protein tyrosine phosphatase-beta, interacts with neuronal receptors and promotes neurite outgrowth.

PTPRB L1CAM

1.86e-05548212700241
Pubmed

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.

RANBP2 TAGLN2 NDUFAF2 NDUFV1 PGM1 L1CAM

2.46e-0542248627342126
Pubmed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

OGDHL NIPSNAP3A PHYH ACACB NDUFAF2 NIPSNAP3B NDUFV1 ETFDH

3.60e-0592648820877624
Pubmed

A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure.

PRICKLE2 TET3

1.44e-041348226989192
Pubmed

EHMT2 directs DNA methylation for efficient gene silencing in mouse embryos.

TET3 TENM2

1.94e-041548226576615
Pubmed

Identification of casein kinase Ialpha interacting protein partners.

ERF CHKA

2.50e-041748212062430
Pubmed

Vangl2 promotes Wnt/planar cell polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidance.

PRICKLE2 L1CAM

2.50e-041748221316586
Pubmed

mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR.

CHKA CDC25B

4.63e-042348222017875
Pubmed

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.

OGDHL MGAM PGM1

5.33e-0411448328245920
Pubmed

Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.

RANBP2 TAGLN2 NDUFAF2 PGM1

6.30e-0428348418854154
Pubmed

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells.

RANBP2 DNAJC1 TAGLN2

6.34e-0412148322412018
Pubmed

N-cadherin can structurally substitute for E-cadherin during intestinal development but leads to polyp formation.

VIL1 L1CAM

7.92e-043048220534673
Pubmed

Nuclear Gene-Encoded Leigh Syndrome Spectrum Overview

NDUFAF2 NDUFV1

7.92e-043048226425749
Pubmed

Analysis of proteomic changes induced upon cellular differentiation of the human intestinal cell line Caco-2.

VIL1 TAGLN2

1.02e-033448221492153
Pubmed

Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.

NIPSNAP3A RANBP2 NIPSNAP3B NDUFV1 PGM1 ETFDH

1.13e-0385948631536960
Pubmed

Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry.

NIPSNAP3A NIPSNAP3B NDUFV1 ETFDH

1.28e-0334348428130547
Cytoband9q21.32

SPATA31D4 SPATA31D3

1.81e-04194829q21.32
Cytoband5q34

PANK3 TENM2

5.20e-04324825q34
CytobandEnsembl 112 genes in cytogenetic band chr5q34

PANK3 TENM2

8.55e-0441482chr5q34
Cytoband9q31.1

NIPSNAP3A NIPSNAP3B

8.55e-04414829q31.1
GeneFamilyFibronectin type III domain containing

PTPRB TNN L1CAM

1.20e-03160243555
GeneFamilySH2 domain containing

SHE SHC2

7.87e-03101242741
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RANBP2 PEX5L

1.01e-02115242769
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK|Striatum / BrainAtlas - Mouse McCarroll V32

USP43 VIL1 SHE PTPRB

1.44e-05137484d37f425b13bc046baa1f8619b98a16b936f88ff6
ToppCellStriatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Striatum / BrainAtlas - Mouse McCarroll V32

USP43 VIL1 SHE PTPRB

1.44e-05137484306b11b3b9e5fd562d845fb5eaa4ac982864efce
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

USP43 VIL1 SHE PTPRB

1.76e-051444841c118b22c2ff3a526a5207d6c9d772636ee065fd
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

USP43 VIL1 SHE PTPRB

2.01e-05149484d9c47f523c75ddcd6131e45d2ffc24b970932cae
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SHE PTPRB ERF PEX5L

2.65e-0516048433050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRB SHC2 NIPSNAP3B ITPRIPL1

3.52e-0517248494093d356b0252b440deda4e1b0ac332b31513f6
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MGAM PTPRB ITPRIPL1 PGM1

4.20e-05180484455d1e3ccf2ab609954f3b870e8f514ddca735f4
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRICKLE2 SHE PTPRB R3HDML

4.98e-0518848451c6796a9488c056a10d048082015342c2e037f9
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRICKLE2 SHE PTPRB R3HDML

4.98e-05188484b651024d58ed1bcfe0d80b21755f8bf709eda81f
ToppCellLPS-antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRICKLE2 PTPRB ACACB CDC25B

4.98e-05188484789d1be574e693d7bdd488f3c72c6df788e47b47
ToppCellLPS-IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRICKLE2 SHE PTPRB ACACB

5.18e-05190484106ea0bb7b99c697ffc5443d72343df2484250c7
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RANBP2 PTPRB CHKA TET3

5.62e-05194484e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellChildren_(3_yrs)-Endothelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

PRICKLE2 SHE PTPRB SHC2

5.73e-05195484094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

STK3 TACC3 ERF CDC25B

5.97e-051974841bb8f9535a9ab6c7a444bcbe346fcc0a13b09bdf
ToppCellPCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating2_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SHE PTPRB TACC3 CDC25B

5.97e-05197484491e12a5fca06b86443c0173f5fa750ea3b8a715
ToppCellPCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating2_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SHE PTPRB TACC3 CDC25B

5.97e-051974848e655db7c6f04d49927a1f0a75178e5955b4af08
ToppCellcontrol-unassigned|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PANK3 ACACB PGBD4 ITPRIPL1

6.20e-0519948450e2da35edff1aadef939cfbd4549f73c1a07717
ToppCellcontrol-unassigned|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PANK3 ACACB PGBD4 ITPRIPL1

6.20e-051994845db7c8089172ac8e796613b3cef618d87007a0ab
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Stem_cells|GW10 / Sample Type, Dataset, Time_group, and Cell type.

TACC3 ERF CDC25B PGM1

6.33e-052004844c22a1f35ff496fa6af2ab171f2936785272bc06
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Stem_cells-Neuroepithelial_cell|GW10 / Sample Type, Dataset, Time_group, and Cell type.

TACC3 ERF CDC25B PGM1

6.33e-052004840632b8d3a1be437f146bc86aae9646303e37a0bd
Drugalpha-bisabolene

MGAM BTN1A1

4.17e-062472CID000086597
Diseasedecanoylcarnitine measurement

DHX8 ETFDH

1.42e-0412442EFO_0021039
DiseaseMITOCHONDRIAL COMPLEX I DEFICIENCY

NDUFAF2 NDUFV1

9.21e-0430442C1838979
DiseaseInherited neuropathies

PHYH L1CAM

1.64e-0340442C0598589
Diseaseepilepsy (implicated_via_orthology)

PRICKLE2 CHKA L1CAM

1.86e-03163443DOID:1826 (implicated_via_orthology)
Diseaseglioblastoma (is_marker_for)

PTPRB L1CAM

1.98e-0344442DOID:3068 (is_marker_for)
DiseaseLeigh Disease

NDUFAF2 NDUFV1

2.25e-0347442C0023264
Diseasealcohol consumption measurement

PIGN MGAM PTPRB ACACB NDUFAF2 TET3 TENM2

2.25e-031242447EFO_0007878

Protein segments in the cluster

PeptideGeneStartEntry
MKTPADTGFAFPDWA

ERF

1

P50548
KKGFDPMTPENGFWA

BTN1A1

381

Q13410
ENGFVKKFEPKSGWM

BCL2A1

141

Q16548
PGPWFNQLDMDGDKT

CEMIP

941

Q8WUJ3
SMVKFPGGTPGRWEK

DNAJC1

341

Q96KC8
PTGWKFFGNLMDASK

PGM1

356

P36871
PKSGFEGMFIRKGQW

RANBP2

1771

P49792
FQMKPGGPALWGDAF

NIPSNAP3A

151

Q9UFN0
PGPKGFSRMDKWKDT

PGBD4

136

Q96DM1
GVGFPSKVPWKKMSA

AFMID

6

Q63HM1
KNGVAFLGPPSEAMW

ACACB

366

O00763
FLGPPSEAMWALGDK

ACACB

371

O00763
VGHFSSFPGMPKWRK

MMP10

96

P09238
QGPLPGTKDDFWKMV

PTPRB

1776

P23467
KMSWFGSKPAPKGSI

GOLGA1

741

Q92805
WGMFSRDQPPGYKKN

MGAM

1151

O43451
TWGMFSRDQPPGYKK

MGAM

2046

O43451
WPGFFNVDGEPKSMT

OGDHL

576

Q9ULD0
NPFKDWPGAFEEGLK

PEX5L

321

Q8IYB4
FQMKPGGPALWGDAF

NIPSNAP3B

151

Q9BS92
DKENDGFVFKMPWKP

CDC25B

191

P30305
EMAPEKWYSLGKVPG

L1CAM

656

P32004
AKKPSFPWFGMDIGG

PANK3

6

Q9H999
GAQPEMWGKHFSNPK

PRICKLE2

436

Q7Z3G6
VLGKKDMGWPFQADG

ITPRIPL1

86

Q6GPH6
PGAFKELFPDWKEKG

ETFDH

121

Q16134
PFNKEPKWLFGTMEK

CHKA

241

P35790
GNWIGESPYKMGKPC

R3HDML

211

Q9H3Y0
MPNDIPEWKKHAFGG

DHX8

531

Q14562
DYPKWEGGVNKMFHG

PHYH

221

O14832
PMKEGNPFGPFWDQF

POFUT1

141

Q9H488
DWDKMDDPNFIPFGG

TACC3

406

Q9Y6A5
DGLFSGDPNWFPKKS

TAGLN2

141

P37802
AGFPTGLKWSFMNKP

NDUFV1

91

P49821
GLKWSFMNKPSDGRP

NDUFV1

96

P49821
DYTMWKNVGKEPAPF

TENM2

2441

Q9NT68
DFLMWKENGKKPGSF

SPATA31D4

421

Q6ZUB0
FWKMLNEPEDQAPGG

OS9

311

Q13438
PANFWMALGGKAPYA

VIL1

591

P09327
DFLMWKENGKKPGSF

SPATA31D3

421

P0C874
SPTPKWFVKAGGVAM

TLCD5

186

Q6ZRR5
EPFPMSKNVFPDNWK

STK3

416

Q13188
KQGPFKTMPLRWSFG

USP43

806

Q70EL4
RMPQWKFAAPGGFLG

SHC2

31

P98077
EGFGDPMKEFWLGLD

TNN

1131

Q9UQP3
GAKPGVSERKMTPFW

PRR19

201

A6NJB7
GKTFQPGSWMPRDGK

NDUFAF2

151

Q8N183
LKGSPGFQDKLWNPM

TET3

1546

O43151
GFQDKLWNPMKGEEG

TET3

1551

O43151
WGSPDILPMFAKGAS

PIGN

136

O95427
GTPFSPDKVGDWMAK

ZBED9

676

Q6R2W3
AGRGPLMAAKWFKEF

SHE

31

Q5VZ18
GKFDELDMSPGDPKW

TBC1D10A

136

Q9BXI6