Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	regulation of small GTPase mediated signal transduction	SYDE2 NTRK1 RAPGEF1 DGKZ AKAP13 ARHGAP35 TEK CDH2 FAM13B STAMBP	6.36e-07	333	80	10	GO:0051056
GeneOntologyBiologicalProcess	regulation of Ras protein signal transduction	SYDE2 NTRK1 RAPGEF1 DGKZ STAMBP	3.88e-06	61	80	5	GO:0046578
GeneOntologyBiologicalProcess	small GTPase-mediated signal transduction	SYDE2 NTRK1 RAPGEF1 DGKZ AKAP13 ARHGAP35 TEK CDH2 KLK1 FAM13B STAMBP	7.07e-06	538	80	11	GO:0007264
GeneOntologyBiologicalProcess	regulation of cellular component size	SPTBN5 CYRIA BMPR2 PCLO SPTAN1 ANXA7 MACF1 RICTOR ARHGAP35	3.99e-05	426	80	9	GO:0032535
GeneOntologyBiologicalProcess	establishment or maintenance of cell polarity	DST FBF1 FSCN2 MACF1 RICTOR ARHGAP35 TEK	6.29e-05	257	80	7	GO:0007163
GeneOntologyBiologicalProcess	regulation of neuron projection development	BMPR2 HECW1 PLXNC1 SYNE1 NTRK1 RAPGEF1 MACF1 ARHGAP35 CDH2 CLIP1	1.25e-04	612	80	10	GO:0010975
GeneOntologyBiologicalProcess	negative regulation of small GTPase mediated signal transduction	RAPGEF1 DGKZ ARHGAP35 STAMBP	1.34e-04	67	80	4	GO:0051058
GeneOntologyBiologicalProcess	regulation of anatomical structure size	SPTBN5 CYRIA BMPR2 PCLO SPTAN1 ANXA7 MACF1 RICTOR ARHGAP35 KLK1	1.35e-04	618	80	10	GO:0090066
GeneOntologyBiologicalProcess	Ras protein signal transduction	SYDE2 NTRK1 RAPGEF1 DGKZ STAMBP	1.41e-04	128	80	5	GO:0007265
GeneOntologyBiologicalProcess	meiotic metaphase I homologous chromosome alignment	BRCA2 CENPC	1.47e-04	5	80	2	GO:0043060
GeneOntologyBiologicalProcess	negative regulation of Ras protein signal transduction	RAPGEF1 DGKZ STAMBP	1.72e-04	28	80	3	GO:0046580
GeneOntologyBiologicalProcess	meiotic metaphase chromosome alignment	BRCA2 CENPC	2.21e-04	6	80	2	GO:0051311
GeneOntologyBiologicalProcess	regulation of protein polymerization	SPTBN5 CYRIA HAUS4 SPTAN1 RICTOR CLIP1	2.78e-04	231	80	6	GO:0032271
GeneOntologyBiologicalProcess	regulation of supramolecular fiber organization	SPTBN5 CYRIA HAUS4 SPTAN1 AKAP13 RICTOR ARHGAP35 CLIP1	2.96e-04	438	80	8	GO:1902903
GeneOntologyBiologicalProcess	protein polymerization	SPTBN5 CYRIA HAUS4 SPTAN1 RICTOR CCDC57 CLIP1	3.16e-04	334	80	7	GO:0051258
GeneOntologyBiologicalProcess	regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	NTRK1 RAPGEF1 RICTOR OTUD3 TEK KLK1 STAMBP	3.16e-04	334	80	7	GO:0051896
GeneOntologyCellularComponent	microtubule organizing center	HAUS4 CLUAP1 BRCA2 MTUS1 CEP112 FBF1 MLF1 ANKRD26 CKAP2L E2F1 ARHGAP35 TEK CCDC57 CLIP1 DHX9 PCNT	3.92e-07	919	81	16	GO:0005815
GeneOntologyCellularComponent	centrosome	HAUS4 CLUAP1 BRCA2 MTUS1 CEP112 FBF1 ANKRD26 CKAP2L E2F1 TEK CCDC57 CLIP1 DHX9 PCNT	1.39e-06	770	81	14	GO:0005813
GeneOntologyCellularComponent	actin cytoskeleton	SPTBN5 DST SPTAN1 FSCN2 ANKRD26 MACF1 AKAP13 ARHGAP35 TEK CDH2 DHX9	1.34e-05	576	81	11	GO:0015629
GeneOntologyCellularComponent	cell cortex	SPTBN5 DST PCLO SPTAN1 MACF1 AKAP13 CDH2 CLIP1	9.50e-05	371	81	8	GO:0005938
GeneOntologyCellularComponent	cortical cytoskeleton	SPTBN5 PCLO SPTAN1 AKAP13 CDH2	1.46e-04	129	81	5	GO:0030863
GeneOntologyCellularComponent	supramolecular fiber	HAUS4 DST MTUS1 KRT35 SYNE1 SPTAN1 FBF1 MACF1 AKAP13 LMNB2 TEK CCDC57 CLIP1 PCNT	1.60e-04	1179	81	14	GO:0099512
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	HAUS4 DST MTUS1 KRT35 FBF1 MACF1 AKAP13 LMNB2 TEK CCDC57 CLIP1 PCNT	1.71e-04	899	81	12	GO:0099513
GeneOntologyCellularComponent	supramolecular polymer	HAUS4 DST MTUS1 KRT35 SYNE1 SPTAN1 FBF1 MACF1 AKAP13 LMNB2 TEK CCDC57 CLIP1 PCNT	1.72e-04	1187	81	14	GO:0099081
GeneOntologyCellularComponent	intermediate filament	DST KRT35 FBF1 MACF1 LMNB2 CLIP1	2.53e-04	227	81	6	GO:0005882
GeneOntologyCellularComponent	cortical actin cytoskeleton	SPTBN5 SPTAN1 AKAP13 CDH2	4.70e-04	93	81	4	GO:0030864
GeneOntologyCellularComponent	spectrin	SPTBN5 SPTAN1	5.25e-04	9	81	2	GO:0008091
GeneOntologyCellularComponent	intermediate filament cytoskeleton	DST KRT35 FBF1 MACF1 LMNB2 CLIP1	5.52e-04	263	81	6	GO:0045111
GeneOntologyCellularComponent	RPAP3/R2TP/prefoldin-like complex	URI1 RPAP3	9.54e-04	12	81	2	GO:1990062
GeneOntologyCellularComponent	fascia adherens	SPTAN1 CDH2	1.13e-03	13	81	2	GO:0005916
GeneOntologyCellularComponent	cell-cell junction	BMPR2 DST SPTAN1 FBF1 SNAP23 TEK CDH2 ARHGEF6	2.05e-03	591	81	8	GO:0005911
GeneOntologyCellularComponent	intercalated disc	DST SPTAN1 CDH2	2.34e-03	68	81	3	GO:0014704
GeneOntologyCellularComponent	lateral element	BRCA2 RAD21L1	2.43e-03	19	81	2	GO:0000800
GeneOntologyCellularComponent	asymmetric synapse	BMPR2 DST PLXNC1 PCLO MACF1 DGKZ CDH2	2.51e-03	477	81	7	GO:0032279
HumanPheno	Intermittent diarrhea	ATP6V0A1 ATRX BRCA2 POLG	7.61e-06	22	31	4	HP:0002254
Domain	Spectrin	SPTBN5 DST SYNE1 SPTAN1 MACF1	3.77e-08	23	79	5	PF00435
Domain	Spectrin_repeat	SPTBN5 DST SYNE1 SPTAN1 MACF1	1.31e-07	29	79	5	IPR002017
Domain	Spectrin/alpha-actinin	SPTBN5 DST SYNE1 SPTAN1 MACF1	2.19e-07	32	79	5	IPR018159
Domain	SPEC	SPTBN5 DST SYNE1 SPTAN1 MACF1	2.19e-07	32	79	5	SM00150
Domain	Actinin_actin-bd_CS	SPTBN5 DST SYNE1 MACF1	2.47e-06	23	79	4	IPR001589
Domain	ACTININ_2	SPTBN5 DST SYNE1 MACF1	2.47e-06	23	79	4	PS00020
Domain	ACTININ_1	SPTBN5 DST SYNE1 MACF1	2.47e-06	23	79	4	PS00019
Domain	CH	SPTBN5 DST SYNE1 MACF1 ARHGEF6	8.07e-06	65	79	5	SM00033
Domain	CH	SPTBN5 DST SYNE1 MACF1 ARHGEF6	1.16e-05	70	79	5	PF00307
Domain	-	SPTBN5 DST SYNE1 MACF1 ARHGEF6	1.25e-05	71	79	5	1.10.418.10
Domain	CH	SPTBN5 DST SYNE1 MACF1 ARHGEF6	1.43e-05	73	79	5	PS50021
Domain	CH-domain	SPTBN5 DST SYNE1 MACF1 ARHGEF6	1.63e-05	75	79	5	IPR001715
Domain	DUF3496	ANKRD26 CCDC144A	5.29e-05	3	79	2	IPR021885
Domain	DUF3496	ANKRD26 CCDC144A	5.29e-05	3	79	2	PF12001
Domain	-	DST MACF1	2.62e-04	6	79	2	3.90.1290.10
Domain	GAR	DST MACF1	2.62e-04	6	79	2	PS51460
Domain	-	DST MACF1	2.62e-04	6	79	2	3.30.920.20
Domain	GAS_dom	DST MACF1	2.62e-04	6	79	2	IPR003108
Domain	GAS2	DST MACF1	2.62e-04	6	79	2	PF02187
Domain	GAS2	DST MACF1	2.62e-04	6	79	2	SM00243
Domain	Plectin_repeat	DST MACF1	3.66e-04	7	79	2	IPR001101
Domain	Plectin	DST MACF1	3.66e-04	7	79	2	PF00681
Domain	PLEC	DST MACF1	3.66e-04	7	79	2	SM00250
Domain	Rho_GTPase_activation_prot	PLXNC1 SYDE2 ARHGAP35 FAM13B	5.28e-04	88	79	4	IPR008936
Domain	GATA_ZN_FINGER_1	ATRX RERE	2.04e-03	16	79	2	PS00344
Domain	GATA_ZN_FINGER_2	ATRX RERE	2.04e-03	16	79	2	PS50114
Domain	RhoGAP	SYDE2 ARHGAP35 FAM13B	2.30e-03	62	79	3	SM00324
Domain	RhoGAP	SYDE2 ARHGAP35 FAM13B	2.41e-03	63	79	3	PF00620
Domain	RHOGAP	SYDE2 ARHGAP35 FAM13B	2.52e-03	64	79	3	PS50238
Domain	RhoGAP_dom	SYDE2 ARHGAP35 FAM13B	2.52e-03	64	79	3	IPR000198
Domain	-	SYDE2 ARHGAP35 FAM13B	2.52e-03	64	79	3	1.10.555.10
Domain	Furin_repeat	FRAS1 CRELD2	2.59e-03	18	79	2	IPR006212
Domain	FU	FRAS1 CRELD2	2.59e-03	18	79	2	SM00261
Domain	Prefoldin	URI1 ATP6V0A1 KRT35	3.52e-03	72	79	3	IPR009053
Pathway	REACTOME_RHO_GTPASE_CYCLE	DST SYDE2 SPTAN1 ANKRD26 SNAP23 RAPGEF1 AKAP13 ARHGAP35 FMNL2 FAM13B ARHGEF6 FAM83B	2.13e-07	439	59	12	MM15595
Pathway	REACTOME_RHO_GTPASE_CYCLE	DST SYDE2 SPTAN1 ANKRD26 SNAP23 RAPGEF1 AKAP13 ARHGAP35 FMNL2 FAM13B ARHGEF6 FAM83B	2.77e-07	450	59	12	M27078
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	DST CENPC SYDE2 SPTAN1 ANKRD26 SNAP23 RAPGEF1 AKAP13 ARHGAP35 FMNL2 CLIP1 FAM13B ARHGEF6 FAM83B	3.25e-07	649	59	14	MM15690
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	DST CENPC SYDE2 SPTAN1 ANKRD26 SNAP23 RAPGEF1 AKAP13 ARHGAP35 FMNL2 CLIP1 FAM13B ARHGEF6 FAM83B	1.13e-06	720	59	14	M41838
Pathway	REACTOME_RND3_GTPASE_CYCLE	DST ANKRD26 ARHGAP35 FAM83B	2.75e-05	42	59	4	M41826
Pathway	REACTOME_RND1_GTPASE_CYCLE	DST ANKRD26 ARHGAP35 FAM83B	2.75e-05	42	59	4	M41828
Pathway	REACTOME_RND3_GTPASE_CYCLE	DST ANKRD26 ARHGAP35 FAM83B	2.75e-05	42	59	4	MM15677
Pathway	REACTOME_RND2_GTPASE_CYCLE	DST ANKRD26 ARHGAP35 FAM83B	3.02e-05	43	59	4	M41827
Pathway	REACTOME_RND1_GTPASE_CYCLE	DST ANKRD26 ARHGAP35 FAM83B	3.02e-05	43	59	4	MM15679
Pathway	REACTOME_RND2_GTPASE_CYCLE	DST ANKRD26 ARHGAP35 FAM83B	3.32e-05	44	59	4	MM15678
Pathway	REACTOME_CDC42_GTPASE_CYCLE	SNAP23 ARHGAP35 FMNL2 FAM13B ARHGEF6	4.67e-04	155	59	5	M41808
Pathway	REACTOME_RHOU_GTPASE_CYCLE	DST SPTAN1 ARHGEF6	5.72e-04	39	59	3	MM15607
Pathway	REACTOME_RHOU_GTPASE_CYCLE	DST SPTAN1 ARHGEF6	6.16e-04	40	59	3	M41816
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTBN5 SPTAN1	7.58e-04	10	59	2	MM15112
Pathway	REACTOME_RAC1_GTPASE_CYCLE	SYDE2 SNAP23 ARHGAP35 FAM13B ARHGEF6	8.11e-04	175	59	5	MM15599
Pubmed	A human MAP kinase interactome.	DST SYNE1 SPTAN1 ANXA7 MKNK2 RAPGEF1 MACF1 AKAP13 FMNL2 FAM13B STAMBP	2.31e-08	486	83	11	20936779
Pubmed	Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.	HAUS4 CEP112 FBF1 ANKRD26 CKAP2L CLIP1 PCNT	6.32e-08	146	83	7	21399614
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	MYT1L DST HECW1 SYNE1 TMCC2 MACF1 ARHGAP35 PCNT	7.04e-08	225	83	8	12168954
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SRRT BMPR2 DST MTUS1 CEP112 SYDE2 SPTAN1 ANKRD26 MACF1 AKAP13 RICTOR PUM1 FAM83B	1.28e-07	861	83	13	36931259
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	DST SYNE1 ANKRD26 MACF1	1.42e-07	20	83	4	21689717
Pubmed	Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.	TMCC2 MACF1 OTUD3 RERE SMYD3	2.38e-07	56	83	5	9455484
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	MYT1L CYRIA ATP6V0A1 DST ATRX SYNE1 POLG SPTAN1 ANXA7 NARS1 MACF1 FMNL2 SMYD3 STAMBP PCNT	3.47e-07	1285	83	15	35914814
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	FRAS1 ATP6V0A1 ATRX CENPC RPAP3 SYNE1 SPTAN1 ANKRD26 SNAP23 MACF1 AKAP13 RICTOR LMNB2 FAM83B DHX9 PCNT	3.97e-07	1487	83	16	33957083
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	MYT1L ATRX CEP112 POLG SNAP23 MACF1 DGKZ RICTOR PUM1 UBN2 F13A1 ARHGEF6 PCNT	1.71e-06	1084	83	13	11544199
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	DST HECW1 SYNE1 SPTAN1 MCC MACF1 DGKZ LMNB2 UBN2 CDH2 CLIP1 PCNT	3.02e-06	963	83	12	28671696
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	5.63e-06	2	83	2	11002341
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	HAUS4 BRCA2 MTUS1 RPAP3 MLF1 ANKRD26 SNAP23 CCDC57 CLIP1 FAM83B PCNT	5.86e-06	853	83	11	28718761
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	SPTBN5 DST SYNE1 SPTAN1 LMNB2 PCNT	5.97e-06	187	83	6	26460568
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	DST ATRX CENPC CEP112 SYNE1 PCLO SPTAN1 FBF1 ANKRD26 MACF1 OTUD3 LMNB2 CCDC57 PCNT	7.56e-06	1442	83	14	35575683
Pubmed	Does 3D Phenotyping Yield Substantial Insights in the Genetics of the Mouse Mandible Shape?	FRAS1 AKAP13 RERE	1.04e-05	18	83	3	26921296
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	BMPR2 URI1 TRPC4AP ATRX POLG ANXA7 MACF1 AKAP13 RERE ARHGAP35 UBN2 CCDC57 SMYD3 PCNT	1.09e-05	1489	83	14	28611215
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	HAUS4 ATRX BRCA2 KRT35 ANKRD26 MACF1 UBN2 FAM83B PCNT	1.15e-05	588	83	9	38580884
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	DST SPTAN1 FBF1 ANKRD26 RICTOR PUM1 CLIP1 FAM83B	1.17e-05	446	83	8	24255178
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FRAS1 HAUS4 DST POLG TMCC2 TASP1 RAPGEF1 AKAP13 LMNB2 ARHGAP35 PUM1 PCNT	1.21e-05	1105	83	12	35748872
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	HAUS4 CLUAP1 URI1 TRPC4AP ATRX RPAP3 MLF1 MCC FMNL2 CLIP1 ARHGEF6 CCDC144A DHX9	1.44e-05	1321	83	13	27173435
Pubmed	Expression of the mouse Macf2 gene during inner ear development.	DST MACF1	1.69e-05	3	83	2	12399109
Pubmed	mTORC2 promotes cell survival through c-Myc-dependent up-regulation of E2F1.	E2F1 RICTOR	1.69e-05	3	83	2	26459601
Pubmed	Essential role for nuclear PTEN in maintaining chromosomal integrity.	CENPC E2F1	1.69e-05	3	83	2	17218262
Pubmed	BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations.	BRCA2 NTRK1	1.69e-05	3	83	2	28591715
Pubmed	SNAP23 deficiency causes severe brain dysplasia through the loss of radial glial cell polarity.	SNAP23 CDH2 PCNT	1.69e-05	21	83	3	33332551
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	ATRX PCLO SPTAN1 MACF1 LMNB2 ARHGAP35	1.98e-05	231	83	6	16452087
Pubmed	Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development.	BMPR2 E2F1 TEK	2.24e-05	23	83	3	25759071
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HECW1 TMCC2 ANKRD26 MACF1 RICTOR ARHGAP35 UBN2 FMNL2	2.40e-05	493	83	8	15368895
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	SRRT URI1 MTUS1 RPAP3 TASP1 AKAP13 FAM83B	2.58e-05	361	83	7	30344098
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	SRRT DST SYNE1 SNAP23 CKAP2L MACF1 LMNB2 PUM1 FAM83B DHX9 PCNT	3.19e-05	1024	83	11	24711643
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	MYT1L DST SYNE1 SPTAN1 MACF1	3.19e-05	151	83	5	17043677
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SRRT ATP6V0A1 DST SYNE1 PCLO SPTAN1 NARS1 MACF1 DGKZ ARHGAP35 FMNL2 CDH2 DHX9	3.32e-05	1431	83	13	37142655
Pubmed	ATRX, a member of the SNF2 family of helicase/ATPases, is required for chromosome alignment and meiotic spindle organization in metaphase II stage mouse oocytes.	ATRX CENPC	3.37e-05	4	83	2	15242786
Pubmed	cDNA cloning, expression pattern, and chromosomal localization of Mlf1, murine homologue of a gene involved in myelodysplasia and acute myeloid leukemia.	NTRK1 MLF1	3.37e-05	4	83	2	10393836
Pubmed	Elevated HMGN4 expression potentiates thyroid tumorigenesis.	ATRX BRCA2	3.37e-05	4	83	2	28186538
Pubmed	Non-TrkA-expressing small DRG neurons are lost in TrkA deficient mice.	NTRK1 KLK1	3.37e-05	4	83	2	7666178
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	DST MACF1	3.37e-05	4	83	2	8954775
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	SPTBN5 DST RPAP3 SYNE1 POLG PCLO MLF1 LMNB2 RERE IFIT1 FAM83B DHX9 PCNT	5.24e-05	1496	83	13	32877691
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	ATRX SYNE1 DGKZ AKAP13 FAM13B	5.31e-05	168	83	5	30631154
Pubmed	Mnk1 and 2 are dispensable for T cell development and activation but important for the pathogenesis of experimental autoimmune encephalomyelitis.	MKNK2 DGKZ	5.60e-05	5	83	2	23269249
Pubmed	Role of CLASP2 in microtubule stabilization and the regulation of persistent motility.	MACF1 CLIP1	5.60e-05	5	83	2	17113391
Pubmed	Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo.	ARHGAP35 TEK	5.60e-05	5	83	2	17562701
Pubmed	Altiratinib Inhibits Tumor Growth, Invasion, Angiogenesis, and Microenvironment-Mediated Drug Resistance via Balanced Inhibition of MET, TIE2, and VEGFR2.	NTRK1 TEK	5.60e-05	5	83	2	26285778
Pubmed	Four proline-rich sequences of the guanine-nucleotide exchange factor C3G bind with unique specificity to the first Src homology 3 domain of Crk.	NTRK1 RAPGEF1	5.60e-05	5	83	2	7806500
Pubmed	MNK1 and MNK2 enforce expression of E2F1, FOXM1, and WEE1 to drive soft tissue sarcoma.	MKNK2 E2F1	5.60e-05	5	83	2	33564073
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	PLXNC1 ANXA7 ANKRD26 SNAP23 RAPGEF1 RICTOR FMNL2 FAM83B	6.57e-05	569	83	8	30639242
Pubmed	Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex.	FBF1 CDH2 PCNT	6.79e-05	33	83	3	30626697
Pubmed	Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.	BMPR2 DST BRCA2 MACF1 E2F1	6.79e-05	177	83	5	22560297
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	DST ANKRD26 SNAP23 MACF1 RICTOR CDH2 FAM83B	6.82e-05	421	83	7	36976175
Pubmed	HAUSP regulates c-MYC expression via de-ubiquitination of TRRAP.	CEP112 FBF1 MACF1	7.43e-05	34	83	3	25925205
Pubmed	BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing.	ATRX BRCA2	8.39e-05	6	83	2	28976962
Pubmed	Suppression of polyploidy by the BRCA2 protein.	BRCA2 E2F1	8.39e-05	6	83	2	17686574
Pubmed	Nerve growth factor activates persistent Rap1 signaling in endosomes.	NTRK1 RAPGEF1	8.39e-05	6	83	2	11466412
Pubmed	Stiffening of Circumferential F-Actin Bands Correlates With Regenerative Failure and May Act as a Biomechanical Brake in the Mammalian Inner Ear.	SPTAN1 CDH2	8.39e-05	6	83	2	35602553
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SRRT DST CENPC RPAP3 SPTAN1 NARS1 MACF1 AKAP13 RICTOR LMNB2 PUM1 DHX9	8.64e-05	1353	83	12	29467282
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SRRT ATRX SPTAN1 RICTOR RERE ARHGAP35 CLIP1 ARHGEF6 DHX9	9.67e-05	774	83	9	15302935
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SEC24D DST SYDE2 ANKRD26 SNAP23 RICTOR FMNL2 FAM83B DHX9	9.96e-05	777	83	9	35844135
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SEC24D DST SYNE1 MACF1	1.03e-04	101	83	4	9872452
Pubmed	Modulation of β-catenin levels regulates cranial neural crest patterning and dispersal into first pharyngeal arch.	E2F1 CDH2	1.17e-04	7	83	2	32427396
Pubmed	Asymmetric distribution of prickle-like 2 reveals an early underlying polarization of vestibular sensory epithelia in the inner ear.	SPTAN1 PCNT	1.17e-04	7	83	2	17376975
Pubmed	Distinct roles for nerve growth factor and brain-derived neurotrophic factor in controlling the rate of hair follicle morphogenesis.	NTRK1 KLK1	1.17e-04	7	83	2	10651992
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	ATP6V0A1 DST BRCA2 PCLO SPTAN1 NARS1 LMNB2 DHX9	1.20e-04	621	83	8	22794259
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	HAUS4 DST CENPC SPTAN1 ANKRD26 UBN2 ARHGEF6 PCNT	1.56e-04	645	83	8	25281560
Pubmed	Identification of a switch in neurotrophin signaling by selective tyrosine phosphorylation.	NTRK1 RAPGEF1	1.56e-04	8	83	2	16284401
Pubmed	ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1.	ATRX SYNE1 ANKRD26 CLIP1	1.59e-04	113	83	4	34474245
Pubmed	AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.	SEC24D ATP6V0A1 SPTAN1 ANXA7 SNAP23 CDH2 DHX9	1.62e-04	484	83	7	31995728
Pubmed	Three ways to make a vesicle.	SEC24D SNAP23 PUM1	1.62e-04	44	83	3	11252894
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	BMPR2 ATP6V0A1 DST PCLO SPTAN1 MACF1	1.87e-04	347	83	6	17114649
Pubmed	Large-scale structural analysis of the classical human protein tyrosine phosphatome.	NTRK1 TEK CDH2	1.97e-04	47	83	3	19167335
Pubmed	TRIP6 functions in brain ciliogenesis.	CLUAP1 CDH2	2.00e-04	9	83	2	34620853
Pubmed	Intercalated cushion cells within the cardiac outflow tract are derived from the myocardial troponin T type 2 (Tnnt2) Cre lineage.	E2F1 CDH2	2.00e-04	9	83	2	29920846
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	DST SYNE1 SPTAN1 MACF1	2.01e-04	120	83	4	31413325
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SRRT DST ATRX SYNE1 TASP1 SNAP23 GOLIM4 MACF1 DGKZ RICTOR UBN2 FAM83B	2.21e-04	1497	83	12	31527615
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	CYRIA DST SPTAN1 MACF1 LMNB2 PCNT	2.28e-04	360	83	6	33111431
Pubmed	Identification of HYPK-interacting proteins reveals involvement of HYPK in regulating cell growth, cell cycle, unfolded protein response and cell death.	SRRT MLF1 LMNB2	2.37e-04	50	83	3	23272104
Pubmed	Analysis of URI nuclear interaction with RPB5 and components of the R2TP/prefoldin-like complex.	URI1 RPAP3	2.50e-04	10	83	2	23667685
Pubmed	Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle.	SYNE1 LMNB2	2.50e-04	10	83	2	28533284
Pubmed	SDCCAG8 regulates pericentriolar material recruitment and neuronal migration in the developing cortex.	CDH2 PCNT	2.50e-04	10	83	2	25088364
Pubmed	RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex.	URI1 RPAP3	2.50e-04	10	83	2	29662061
Pubmed	ACF7 regulates cytoskeletal-focal adhesion dynamics and migration and has ATPase activity.	MACF1 CLIP1	2.50e-04	10	83	2	18854161
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	SRRT DST SYNE1 SPTAN1 ANXA7 MACF1 LMNB2 ARHGAP35 ARHGEF6 DHX9	2.54e-04	1082	83	10	38697112
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	SEC24D DST CEP112 SPTAN1 ANXA7 SNAP23 GOLIM4 CRELD2 MACF1 AKAP13 DHX9	2.57e-04	1297	83	11	33545068
Pubmed	Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction.	ATP6V0A1 PCLO SPTAN1 DHX9	2.81e-04	131	83	4	28634551
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	DST RPAP3 ANKRD26 NARS1 MACF1 RICTOR FAM83B DHX9	2.92e-04	708	83	8	39231216
Pubmed	Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure.	E2F1 CDH2	3.05e-04	11	83	2	33103996
Pubmed	The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway.	DST MACF1	3.05e-04	11	83	2	16815997
Pubmed	A conserved KASH domain protein associates with telomeres, SUN1, and dynactin during mammalian meiosis.	CENPC SYNE1	3.05e-04	11	83	2	22826121
Pubmed	LATS1/2 control TGFB-directed epithelial-to-mesenchymal transition in the murine dorsal cranial neuroepithelium through YAP regulation.	E2F1 CDH2	3.05e-04	11	83	2	36125128
Pubmed	The centrosome protein AKNA regulates neurogenesis via microtubule organization.	CDH2 PCNT	3.05e-04	11	83	2	30787442
Pubmed	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	SYNE1 PCLO	3.05e-04	11	83	2	20351715
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	RPAP3 SPTAN1 ANKRD26 MACF1 AKAP13 ARHGAP35 PUM1 UBN2	3.39e-04	724	83	8	36232890
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	HECW1 RPAP3 SPTAN1 LMNB2 DHX9	3.39e-04	250	83	5	33536335
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	BMPR2 TRPC4AP SPTAN1 ANXA7 MCC SNAP23 CRELD2 DGKZ F13A1 ARHGEF6	3.43e-04	1124	83	10	21900206
Pubmed	Spatiotemporal patterns of expression of neurotrophins and neurotrophin receptors in mice suggest functional roles in testicular and epididymal morphogenesis.	NTRK1 KLK1	3.66e-04	12	83	2	10491653
Pubmed	A new meiosis-specific cohesin complex implicated in the cohesin code for homologous pairing.	CENPC RAD21L1	3.66e-04	12	83	2	21274006
Pubmed	High-resolution mapping of the protein interaction network for the human transcription machinery and affinity purification of RNA polymerase II-associated complexes.	URI1 RPAP3	3.66e-04	12	83	2	19450687
Pubmed	Syndactyly in a novel Fras1(rdf) mutant results from interruption of signals for interdigital apoptosis.	FRAS1 BMPR2	3.66e-04	12	83	2	26813283
Pubmed	The deubiquitylase OTUD3 stabilizes GRP78 and promotes lung tumorigenesis.	OTUD3 DHX9	3.66e-04	12	83	2	31266968
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	DST SYDE2 PCLO NARS1 AKAP13 LMNB2 FMNL2 DHX9	3.78e-04	736	83	8	29676528
Pubmed	Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.	TRPC4AP MKNK2 TASP1 GOLIM4 E2F1	3.85e-04	257	83	5	30945288
Interaction	RAC1 interactions	BMPR2 DST SYDE2 SPTAN1 FBF1 ANKRD26 SNAP23 RAPGEF1 MACF1 RICTOR LMNB2 ARHGAP35 FMNL2 CDH2 CLIP1 FAM13B ARHGEF6 FAM83B DHX9	3.01e-08	1063	81	19	int:RAC1
Interaction	YWHAZ interactions	DST ANKRD34B MTUS1 CEP112 SYDE2 NTRK1 SPTAN1 MLF1 MCC ANKRD26 MACF1 AKAP13 RICTOR PUM1 CLIP1 FAM13B ARHGEF6 FAM83B PCNT	8.56e-07	1319	81	19	int:YWHAZ
Interaction	RND3 interactions	SRRT BMPR2 DST SPTAN1 ANKRD26 SNAP23 RICTOR ARHGAP35 FAM83B	1.50e-06	273	81	9	int:RND3
Interaction	FLOT1 interactions	DST PCLO SPTAN1 FBF1 ANKRD26 SNAP23 RAPGEF1 MACF1 RICTOR FMNL2 FAM83B	3.05e-06	475	81	11	int:FLOT1
Interaction	MAPRE3 interactions	DST CENPC MTUS1 CKAP2L MACF1 CLIP1 FAM83B PCNT	4.00e-06	230	81	8	int:MAPRE3
Interaction	RHOV interactions	BMPR2 DST SPTAN1 ANKRD26 SNAP23 RICTOR ARHGEF6 FAM83B	6.00e-06	243	81	8	int:RHOV
Interaction	RAC3 interactions	BMPR2 SPTAN1 ANKRD26 SNAP23 RAPGEF1 MACF1 RICTOR LMNB2 ARHGAP35 CDH2 ARHGEF6 FAM83B	6.47e-06	619	81	12	int:RAC3
Interaction	RND1 interactions	BMPR2 DST SPTAN1 ANKRD26 SNAP23 RICTOR ARHGAP35 FAM83B	6.57e-06	246	81	8	int:RND1
Interaction	CEP63 interactions	HAUS4 DST SYNE1 SPTAN1 FBF1 MACF1 PCNT	7.75e-06	179	81	7	int:CEP63
Interaction	RHOJ interactions	BMPR2 ATP6V0A1 SPTAN1 ANKRD26 SNAP23 MACF1 RICTOR LMNB2 ARHGAP35 CDH2 ARHGEF6 FAM83B	8.11e-06	633	81	12	int:RHOJ
Interaction	RND2 interactions	BMPR2 ATP6V0A1 DST SPTAN1 ANKRD26 SNAP23 RICTOR LMNB2 ARHGAP35 FAM83B	1.05e-05	440	81	10	int:RND2
Interaction	YWHAB interactions	URI1 DST RPAP3 CEP112 SYDE2 NTRK1 SPTAN1 MCC ANKRD26 MACF1 AKAP13 RICTOR PUM1 FAM83B DHX9	1.09e-05	1014	81	15	int:YWHAB
Interaction	RHOQ interactions	BMPR2 ATP6V0A1 DST SPTAN1 ANKRD26 SNAP23 RAPGEF1 RICTOR ARHGEF6 FAM83B	1.09e-05	442	81	10	int:RHOQ
Interaction	RAC2 interactions	BMPR2 ATP6V0A1 DST SPTAN1 SNAP23 MACF1 RICTOR LMNB2 ARHGAP35 CDH2 ARHGEF6 FAM83B	1.52e-05	674	81	12	int:RAC2
Interaction	RHOD interactions	BMPR2 SPTAN1 ANKRD26 SNAP23 MACF1 RICTOR LMNB2 ARHGAP35 FMNL2 CDH2 FAM83B	1.76e-05	572	81	11	int:RHOD
Interaction	RDX interactions	DST NTRK1 SPTAN1 SNAP23 MACF1 RICTOR FAM83B PCNT	1.86e-05	284	81	8	int:RDX
Interaction	SFN interactions	DST MTUS1 RPAP3 CEP112 NTRK1 SPTAN1 ANKRD26 MACF1 AKAP13 RICTOR PUM1 FAM83B	1.97e-05	692	81	12	int:SFN
Interaction	RHOC interactions	BMPR2 ATP6V0A1 FBF1 ANKRD26 SNAP23 MACF1 RICTOR LMNB2 FMNL2 CDH2 FAM83B	2.13e-05	584	81	11	int:RHOC
Interaction	EPB41L4A interactions	DST SPTAN1 ANKRD26 SNAP23 MACF1 FAM83B	2.14e-05	140	81	6	int:EPB41L4A
Interaction	APC interactions	TRAF1 DST SYNE1 ANXA7 MACF1 AKAP13 RICTOR CLIP1 FAM83B	2.60e-05	389	81	9	int:APC
Interaction	YWHAH interactions	SRRT DST MTUS1 CEP112 SYDE2 NTRK1 SPTAN1 ANKRD26 MACF1 AKAP13 RICTOR PUM1 ARHGEF6 FAM83B PCNT	2.89e-05	1102	81	15	int:YWHAH
Interaction	YWHAG interactions	DST MTUS1 RPAP3 CEP112 SYDE2 NTRK1 SPTAN1 MCC ANKRD26 MACF1 AKAP13 RICTOR PUM1 FAM13B ARHGEF6 FAM83B	3.12e-05	1248	81	16	int:YWHAG
Interaction	YWHAE interactions	DST RPAP3 CEP112 SYDE2 NTRK1 SPTAN1 MCC ANKRD26 MACF1 AKAP13 RICTOR PUM1 CLIP1 FAM13B FAM83B DHX9	3.37e-05	1256	81	16	int:YWHAE
Interaction	SPTBN5 interactions	SPTBN5 SPTAN1 FBF1	3.37e-05	16	81	3	int:SPTBN5
Interaction	MAPRE1 interactions	DST MTUS1 NTRK1 SPTAN1 ANKRD26 CKAP2L MACF1 LMNB2 CLIP1 PCNT	3.96e-05	514	81	10	int:MAPRE1
Interaction	UTP14C interactions	TRAF1 BRCA2 MCC CCDC57	4.85e-05	50	81	4	int:UTP14C
Interaction	AFDN interactions	DST NTRK1 ANKRD26 SNAP23 MACF1 RICTOR FMNL2 FAM83B	5.76e-05	333	81	8	int:AFDN
Interaction	CCDC120 interactions	TRAF1 HAUS4 KRT35 LMNB2 RERE CCDC57	6.14e-05	169	81	6	int:CCDC120
Interaction	RBM11 interactions	SRRT TRPC4AP DST ATRX POLG STAMBP	6.14e-05	169	81	6	int:RBM11
Interaction	CDC42 interactions	BMPR2 ATP6V0A1 SYNE1 SPTAN1 ANKRD26 SNAP23 GOLIM4 RICTOR LMNB2 ARHGAP35 FMNL2 CLIP1 FAM13B ARHGEF6 FAM83B DHX9	6.28e-05	1323	81	16	int:CDC42
Interaction	OFD1 interactions	URI1 RPAP3 NTRK1 FBF1 CCDC57 FAM83B DRC3 PCNT	7.68e-05	347	81	8	int:OFD1
Interaction	CTTN interactions	SRRT BRCA2 NTRK1 SPTAN1 RICTOR OTUD3 ARHGAP35 UBN2 FMNL2	8.01e-05	450	81	9	int:CTTN
Interaction	DIRAS3 interactions	DST SPTAN1 ANKRD26 SNAP23 MACF1 RICTOR FAM83B	8.88e-05	262	81	7	int:DIRAS3
Interaction	CALD1 interactions	DST SYDE2 NTRK1 SPTAN1 RICTOR UBN2 FMNL2	9.53e-05	265	81	7	int:CALD1
Interaction	GOLGA1 interactions	DST MTUS1 ANKRD26 MACF1 ARHGAP35 PCNT	9.53e-05	183	81	6	int:GOLGA1
Interaction	SOHLH1 interactions	TRAF1 HAUS4 MTUS1 MLF1 RICTOR	1.01e-04	115	81	5	int:SOHLH1
Interaction	CEP135 interactions	HAUS4 BRCA2 CEP112 FBF1 ANKRD26 FAM83B PCNT	1.12e-04	272	81	7	int:CEP135
Interaction	WASHC2A interactions	NTRK1 SPTAN1 FBF1 MLF1 RICTOR	1.33e-04	122	81	5	int:WASHC2A
Interaction	TTC3 interactions	ATP6V0A1 DST POLG SPTAN1 FMNL2	1.43e-04	124	81	5	int:TTC3
Interaction	DCTN1 interactions	SEC24D HAUS4 DST MTUS1 NTRK1 CKAP2L MACF1 RICTOR CLIP1	1.70e-04	497	81	9	int:DCTN1
Interaction	MIB1 interactions	HAUS4 BMPR2 NTRK1 ANKRD26 OTUD3 ARHGAP35 PCNT	1.85e-04	295	81	7	int:MIB1
Interaction	TRIM52 interactions	URI1 BRCA2 MTUS1 RICTOR PCNT	1.99e-04	133	81	5	int:TRIM52
Interaction	SHC3 interactions	TRAF1 KRT35 NTRK1 SMYD3	2.02e-04	72	81	4	int:SHC3
Interaction	PFN1 interactions	NTRK1 PCLO SPTAN1 ANKRD26 MACF1 AKAP13 ARHGAP35 FMNL2 PCNT	2.03e-04	509	81	9	int:PFN1
Interaction	RHOU interactions	BMPR2 DST SPTAN1 ANKRD26 SNAP23 MACF1 RICTOR ARHGEF6 FAM83B	2.06e-04	510	81	9	int:RHOU
Interaction	RHOH interactions	BMPR2 ATP6V0A1 DST SPTAN1 ANKRD26 SNAP23 RICTOR LMNB2 FAM83B	2.12e-04	512	81	9	int:RHOH
Interaction	HERC2P9 interactions	MTUS1 MLF1 RICTOR	2.35e-04	30	81	3	int:HERC2P9
Interaction	C11orf52 interactions	DST SPTAN1 ANKRD26 SNAP23 MACF1 RICTOR FAM83B	2.55e-04	311	81	7	int:C11orf52
Interaction	NDC80 interactions	HAUS4 CENPC NTRK1 MLF1 ANKRD26 CCDC57 PCNT	2.60e-04	312	81	7	int:NDC80
Interaction	RHOG interactions	BMPR2 POLG SPTAN1 ANKRD26 SNAP23 RAPGEF1 MACF1 RICTOR LMNB2 ARHGAP35 CDH2 FAM83B	2.67e-04	910	81	12	int:RHOG
Interaction	EXOC1 interactions	DST NTRK1 SPTAN1 MACF1 PCNT	2.79e-04	143	81	5	int:EXOC1
Interaction	CLTC interactions	ATP6V0A1 MTUS1 RPAP3 NTRK1 SPTAN1 FBF1 MCC RICTOR STAMBP FAM83B	2.89e-04	655	81	10	int:CLTC
Interaction	DSCR9 interactions	DST SYNE1 NARS1 MACF1 STAMBP	3.17e-04	147	81	5	int:DSCR9
Interaction	PLEC interactions	DST BRCA2 SYDE2 SPTAN1 MLF1 MACF1 RICTOR PCNT	3.32e-04	430	81	8	int:PLEC
Interaction	TRIM29 interactions	SRRT BRCA2 KRT35 SYNE1 FBF1 CCDC57	3.37e-04	231	81	6	int:TRIM29
Interaction	PCM1 interactions	HAUS4 CEP112 NTRK1 FBF1 ANKRD26 CKAP2L CCDC57 PCNT	3.53e-04	434	81	8	int:PCM1
Interaction	EZR interactions	DST NTRK1 SPTAN1 MCC ANKRD26 SNAP23 MACF1 RICTOR ARHGAP35	3.73e-04	553	81	9	int:EZR
Interaction	TXLNA interactions	DST KRT35 NTRK1 FBF1 MCC CCDC57	3.78e-04	236	81	6	int:TXLNA
Interaction	SYNE3 interactions	DST BRCA2 FBF1 ANKRD26 MACF1 PUM1 FAM83B PCNT	4.11e-04	444	81	8	int:SYNE3
Interaction	DYNLT1 interactions	BMPR2 DST MTUS1 SNAP23 LMNB2 CLIP1	4.22e-04	241	81	6	int:DYNLT1
Interaction	PCNT interactions	MYT1L DST SYNE1 SPTAN1 MACF1 PCNT	4.22e-04	241	81	6	int:PCNT
Interaction	HSP90AB1 interactions	CLUAP1 BRCA2 RPAP3 NTRK1 SPTAN1 TASP1 MCC RICTOR CLIP1 IFIT1 SMYD3 CCDC144A	4.34e-04	960	81	12	int:HSP90AB1
Interaction	STX6 interactions	DST SPTAN1 ANKRD26 SNAP23 CKAP2L MACF1 RICTOR FAM83B	4.36e-04	448	81	8	int:STX6
Interaction	CYRIA interactions	CYRIA RICTOR	4.40e-04	8	81	2	int:CYRIA
Interaction	TSHZ2 interactions	TRAF1 MCC CCDC57	4.40e-04	37	81	3	int:TSHZ2
Interaction	HAUS6 interactions	HAUS4 NTRK1 FBF1 MLF1 RICTOR	4.80e-04	161	81	5	int:HAUS6
Interaction	YWHAQ interactions	DST MTUS1 CEP112 SYDE2 NTRK1 ANKRD26 MACF1 E2F1 AKAP13 RICTOR PUM1 FAM83B DHX9	4.89e-04	1118	81	13	int:YWHAQ
Interaction	CTNNA1 interactions	NTRK1 SPTAN1 ANKRD26 SNAP23 MACF1 FMNL2 CDH2	4.93e-04	347	81	7	int:CTNNA1
Interaction	DTNBP1 interactions	DST BRCA2 SYNE1 MACF1 PCNT	4.94e-04	162	81	5	int:DTNBP1
Interaction	POLR3A interactions	URI1 RPAP3 NTRK1 MCC RICTOR	5.08e-04	163	81	5	int:POLR3A
Interaction	C6orf141 interactions	BRCA2 MLF1 RICTOR FAM83B	5.17e-04	92	81	4	int:C6orf141
Interaction	RHOB interactions	BMPR2 SPTAN1 ANKRD26 SNAP23 MACF1 AKAP13 RICTOR ARHGAP35 FMNL2 CDH2 FAM83B	5.22e-04	840	81	11	int:RHOB
Interaction	GAN interactions	SPTBN5 DST SYNE1 SPTAN1 LMNB2 PCNT	5.45e-04	253	81	6	int:GAN
Interaction	GJA1 interactions	DST SPTAN1 ANKRD26 SNAP23 MACF1 RICTOR CDH2 STAMBP FAM83B	5.46e-04	583	81	9	int:GJA1
Interaction	DBR1 interactions	ATRX NTRK1 SPTAN1	5.55e-04	40	81	3	int:DBR1
Interaction	PDIA4 interactions	SRRT SYNE1 NTRK1 PCLO CKAP2L RICTOR CDH2 ARHGEF6	5.82e-04	468	81	8	int:PDIA4
Interaction	EPHA2 interactions	ATP6V0A1 DST NTRK1 ANKRD26 SNAP23 GOLIM4 MACF1 RICTOR CDH2 FAM83B	6.00e-04	719	81	10	int:EPHA2
Interaction	IQGAP1 interactions	CLUAP1 TRPC4AP DST NTRK1 SPTAN1 GOLIM4 RICTOR CLIP1 DHX9	6.02e-04	591	81	9	int:IQGAP1
Interaction	NIN interactions	HAUS4 BRCA2 ANKRD26 CCDC57 CLIP1 FAM83B PCNT	6.03e-04	359	81	7	int:NIN
Interaction	CDC5L interactions	MYT1L DST CENPC SYNE1 NTRK1 SPTAN1 MACF1 RICTOR SNX12 DHX9 PCNT	6.04e-04	855	81	11	int:CDC5L
Interaction	FAM167A interactions	HAUS4 MTUS1 RICTOR ARHGAP35	6.08e-04	96	81	4	int:FAM167A
Interaction	TRAF3IP1 interactions	CLUAP1 DST MACF1 PCNT	6.08e-04	96	81	4	int:TRAF3IP1
Interaction	CAV1 interactions	BMPR2 DST NTRK1 SPTAN1 ANKRD26 SNAP23 MACF1 RICTOR TEK FAM83B	6.33e-04	724	81	10	int:CAV1
Interaction	HRAS interactions	BMPR2 ANKRD34B SPTAN1 ANXA7 SNAP23 RAPGEF1 DGKZ RICTOR OTUD3 FMNL2	6.39e-04	725	81	10	int:HRAS
Interaction	GIT1 interactions	SRRT NTRK1 PCLO RICTOR ARHGEF6	6.49e-04	172	81	5	int:GIT1
Interaction	AKAP17A interactions	TRAF1 HAUS4 DST RICTOR	6.82e-04	99	81	4	int:AKAP17A
Interaction	MYT1L interactions	MYT1L PCNT	7.03e-04	10	81	2	int:MYT1L
Interaction	RDM1 interactions	BRCA2 CCDC57	7.03e-04	10	81	2	int:RDM1
Interaction	PER1 interactions	BRCA2 MCC CCDC57 DRC3	7.09e-04	100	81	4	int:PER1
Interaction	NCAPG2 interactions	SRRT CLUAP1 NTRK1 NARS1	7.09e-04	100	81	4	int:NCAPG2
Interaction	CXADR interactions	DST ANKRD26 SNAP23 MACF1 RICTOR FMNL2 FAM83B	7.09e-04	369	81	7	int:CXADR
Interaction	SCRIB interactions	NTRK1 FBF1 MCC RICTOR FMNL2 ARHGEF6	7.09e-04	266	81	6	int:SCRIB
Interaction	JUP interactions	SRRT NTRK1 SPTAN1 NARS1 RICTOR LMNB2 FMNL2 CDH2	7.34e-04	485	81	8	int:JUP
Interaction	TTI1 interactions	URI1 BRCA2 RPAP3 NTRK1	7.36e-04	101	81	4	int:TTI1
Interaction	ZNF417 interactions	TRAF1 KRT35 TMCC2 MCC CCDC57	7.57e-04	178	81	5	int:ZNF417
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	HECW1 SYDE2 PCLO	1.68e-04	36	54	3	823
GeneFamily	EF-hand domain containing\|Spectrins	SPTBN5 SPTAN1	1.82e-04	7	54	2	1113
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	2.42e-04	8	54	2	939
Coexpression	CUI_DEVELOPING_HEART_TRABECULAR_ATRIAL_CARDIOMYOCYTE	FRAS1 BMPR2 DST SPTAN1 ANKRD26 GOLIM4 MACF1 CDH2	1.03e-07	179	83	8	M39308
Coexpression	LAKE_ADULT_KIDNEY_C22_ENDOTHELIAL_CELLS_GLOMERULAR_CAPILLARIES	BMPR2 CEP112 SYNE1 MACF1 TEK FMNL2 SMYD3	2.72e-07	137	83	7	M39241
Coexpression	GSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_UP	DST CEP112 SYNE1 MLF1 CRELD2 IFIT1 F13A1	5.51e-07	152	83	7	M2964
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	SEC24D URI1 DST ATRX BRCA2 CENPC MACF1 AKAP13 ARHGAP35 PUM1 CDH2 CLIP1 PCNT	2.81e-06	856	83	13	M4500
Coexpression	GSE21927_C26GM_VS_4T1_TUMOR_MONOCYTE_BALBC_DN	ATRX SYNE1 SPTAN1 SNAP23 MACF1 AKAP13 ARHGEF6	3.34e-06	199	83	7	M7607
Coexpression	HALLMARK_MITOTIC_SPINDLE	DST BRCA2 SPTAN1 AKAP13 RICTOR CLIP1 PCNT	3.34e-06	199	83	7	M5893
Coexpression	GSE24726_WT_VS_E2_2_KO_PDC_DAY6_POST_DELETION_DN	ATRX SNAP23 NARS1 RERE PUM1 IFIT1 ARHGEF6	3.45e-06	200	83	7	M8056
Coexpression	GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA5_STIM_CD8_TCELL_UP	ATRX MKNK2 ANKRD26 AKAP13 RERE STAMBP PCNT	3.45e-06	200	83	7	M8050
Coexpression	LAKE_ADULT_KIDNEY_C24_ENDOTHELIAL_CELLS_AEA_AND_DVR	BMPR2 DST MTUS1 SYNE1 MACF1 AKAP13	9.00e-06	152	83	6	M39243
Coexpression	CARRILLOREIXACH_HEPATOBLASTOMA_VS_NORMAL_HYPOMETHYLATED_AND_UP	PLXNC1 CKAP2L RERE FMNL2 F13A1 DHX9	1.29e-05	162	83	6	M45037
Coexpression	DANG_REGULATED_BY_MYC_DN	ATRX SPTAN1 MCC CKAP2L DGKZ CDH2 IFIT1	1.52e-05	251	83	7	M2310
Coexpression	CUI_TCF21_TARGETS_2_DN	CYRIA DST MTUS1 TMCC2 MCC SNAP23 MACF1 RICTOR TEK FMNL2 KLK1 CLIP1	1.53e-05	854	83	12	M1533
Coexpression	CUI_TCF21_TARGETS_2_DN	CYRIA DST MTUS1 TMCC2 MCC SNAP23 MACF1 RICTOR TEK FMNL2 KLK1 CLIP1	2.26e-05	888	83	12	MM1018
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP	CYRIA BMPR2 URI1 ATRX RPAP3 PLXNC1 ANXA7 MCC SNAP23 CRELD2 MACF1 PUM1 CLIP1 STAMBP	2.60e-05	1215	83	14	M41122
Coexpression	GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_UP	SEC24D TRAF1 BMPR2 POLG MACF1 F13A1	4.12e-05	199	83	6	M7656
Coexpression	GSE3982_EOSINOPHIL_VS_DC_UP	SRRT CYRIA SYNE1 MLF1 GOLIM4 ARHGEF6	4.12e-05	199	83	6	M5399
Coexpression	GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_DC_DN	DST BRCA2 SYNE1 DGKZ CDH2 ARHGEF6	4.24e-05	200	83	6	M5204
Coexpression	GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_UP	ANXA7 TASP1 GOLIM4 CLIP1 CHRND DRC3	4.24e-05	200	83	6	M9000
Coexpression	LAKE_ADULT_KIDNEY_C2_PODOCYTES	BMPR2 DST CEP112 GOLIM4 MACF1 FMNL2	5.86e-05	212	83	6	M39221
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	TRAF1 URI1 ATRX CENPC SYNE1 SPTAN1 RAPGEF1 MACF1 AKAP13 RICTOR ARHGAP35 CLIP1 FAM13B ARHGEF6 DHX9	6.22e-05	1492	83	15	M40023
Coexpression	LAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2	FRAS1 PCLO ANKRD26 AKAP13 RERE SMYD3	7.38e-05	221	83	6	M39222
Coexpression	GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_BALBC_MOUSE_DN	CYRIA SYDE2 DGKZ RERE FAM83B	8.13e-05	139	83	5	M2928
Coexpression	MARSON_BOUND_BY_FOXP3_UNSTIMULATED	HAUS4 URI1 TRPC4AP ATP6V0A1 CENPC PLXNC1 ANXA7 FSCN2 FAM13B SNX12 SMYD3 ARHGEF6 DRC3	1.34e-04	1239	83	13	M1743
Coexpression	GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_DN	SYNE1 NKPD1 OTUD3 FMNL2 F13A1	1.44e-04	157	83	5	M7733
Coexpression	GSE45365_NK_CELL_VS_CD8_TCELL_UP	BMPR2 ATP6V0A1 PLXNC1 CRELD2 FMNL2	1.53e-04	159	83	5	M10025
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN	DST CENPC CDH2 PCNT	1.56e-04	85	83	4	M10575
Coexpression	CEBALLOS_TARGETS_OF_TP53_AND_MYC_DN	ATRX CKAP2L DGKZ	1.56e-04	33	83	3	M1252
Coexpression	LAKE_ADULT_KIDNEY_C29_UNKNOWN_NOVEL_PT_CFH_POS_SUBPOPULATION_S2	DST CEP112 SYNE1 MACF1	1.63e-04	86	83	4	M39248
Coexpression	MARSON_BOUND_BY_FOXP3_UNSTIMULATED	HAUS4 URI1 TRPC4AP ATP6V0A1 CENPC PLXNC1 ANXA7 FSCN2 FAM13B SNX12 SMYD3 ARHGEF6 DRC3	1.81e-04	1277	83	13	MM1032
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	MYT1L CYRIA ATRX MTUS1 PLXNC1 PCLO RICTOR ARHGAP35 UBN2 FMNL2 CLIP1 CCDC144A	1.83e-04	1106	83	12	M39071
Coexpression	GSE25677_R848_VS_MPL_AND_R848_STIM_BCELL_DN	MKNK2 GOLIM4 RAPGEF1 AKAP13 DHX9	1.87e-04	166	83	5	M8182
Coexpression	KIM_WT1_TARGETS_8HR_UP	BMPR2 SYNE1 MKNK2 SNAP23 GOLIM4	1.92e-04	167	83	5	M8857
Coexpression	BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING	SRRT CYRIA DST SYNE1 NTRK1 RAPGEF1 ARHGAP35 DHX9	2.03e-04	506	83	8	M253
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	CENPC MTUS1 RPAP3 PLXNC1 CEP112 GOLIM4 NARS1 CLIP1 FAM13B	2.31e-04	656	83	9	M18979
Coexpression	BROWNE_HCMV_INFECTION_14HR_DN	CLUAP1 DST SYNE1 FSCN2 AKAP13 STAMBP	3.22e-04	290	83	6	M13251
Coexpression	GSE21927_GMCSF_IL6_VS_GMCSF_GCSF_TREATED_BONE_MARROW_UP	CYRIA RAD21L1 AKAP13 IFIT1 STAMBP	3.24e-04	187	83	5	M7572
Coexpression	GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_4H_DN	TRAF1 RICTOR CCDC57 IFIT1 DRC3	3.40e-04	189	83	5	M4261
Coexpression	GSE11057_CD4_CENT_MEM_VS_PBMC_DN	ATP6V0A1 PLXNC1 SNAP23 FMNL2 F13A1	3.93e-04	195	83	5	M3117
Coexpression	GSE19401_PLN_VS_PEYERS_PATCH_FOLLICULAR_DC_UP	ATRX SYNE1 RERE TEK PCNT	4.02e-04	196	83	5	M7666
Coexpression	GSE22886_IL2_VS_IL15_STIM_NKCELL_UP	SPTBN5 FRAS1 FSCN2 TEK CHRND	4.02e-04	196	83	5	M4514
Coexpression	GSE7509_DC_VS_MONOCYTE_WITH_FCGRIIB_STIM_DN	BMPR2 BRCA2 MACF1 RERE IFIT1	4.12e-04	197	83	5	M6835
Coexpression	GSE8685_IL2_STARVED_VS_IL2_ACT_IL2_STARVED_CD4_TCELL_DN	SEC24D PXT1 CKAP2L CRELD2 DHX9	4.21e-04	198	83	5	M325
Coexpression	GSE25085_FETAL_BM_VS_ADULT_BM_SP4_THYMIC_IMPLANT_DN	SEC24D CYRIA TRAF1 CRELD2 FMNL2	4.31e-04	199	83	5	M8070
Coexpression	GSE14350_TREG_VS_TEFF_UP	SYNE1 MKNK2 DGKZ PUM1 IFIT1	4.31e-04	199	83	5	M3417
Coexpression	GSE41867_NAIVE_VS_EFFECTOR_CD8_TCELL_DN	CYRIA TRAF1 CLUAP1 ANKRD26 E2F1	4.41e-04	200	83	5	M9475
Coexpression	GSE8835_CD4_VS_CD8_TCELL_UP	CLUAP1 MKNK2 PUM1 SMYD3 PCNT	4.41e-04	200	83	5	M6254
Coexpression	GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN	CYRIA TRAF1 BRCA2 PLXNC1 IFIT1	4.41e-04	200	83	5	M5228
Coexpression	GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_DN	CYRIA RAPGEF1 AKAP13 IFIT1 FAM13B	4.41e-04	200	83	5	M7150
Coexpression	GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_DN	ATP6V0A1 PLXNC1 SYNE1 RICTOR IFIT1	4.41e-04	200	83	5	M5724
Coexpression	GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_STAT3_KO_CD4_TCELL_UP	AKR1E2 BMPR2 NARS1 SNX12 SMYD3	4.41e-04	200	83	5	M7431
Coexpression	GSE7831_1H_VS_4H_INFLUENZA_STIM_PDC_UP	AKR1E2 TRPC4AP PLXNC1 PCLO TEK	4.41e-04	200	83	5	M6963
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	BRCA2 CENPC RPAP3 PLXNC1 POLG PCLO SPTAN1 ANKRD26 CDH2 DHX9 PCNT	5.48e-06	532	81	11	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	ATRX BRCA2 RPAP3 PLXNC1 PCLO ANKRD26 GOLIM4 CRELD2 RERE FMNL2 CDH2 CLIP1	7.04e-05	831	81	12	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	gudmap_RNAseq_p2_Glomerlular Endothelial_2500_K1	CYRIA TRAF1 BMPR2 MTUS1 SYNE1 SPTAN1 ANXA7 TMCC2 MCC RAPGEF1 DGKZ AKAP13	8.73e-05	850	81	12	gudmap_RNAseq_p2_Glomerlular Endothelial_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#4	ATRX BRCA2 PCLO ANKRD26 MACF1 CLIP1	9.34e-05	192	81	6	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K4
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	BMPR2 DST ATRX SPTAN1 MACF1 DGKZ TEK IFIT1 FAM13B PCNT	4.41e-12	200	83	10	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	BMPR2 DST ATRX SPTAN1 MACF1 TEK IFIT1	9.63e-08	200	83	7	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMPR2 ATRX CEP112 GOLIM4 MACF1 DHX9	9.67e-07	176	83	6	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEC24D FRAS1 DST PCLO GOLIM4 CDH2	1.03e-06	178	83	6	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CYRIA RAPGEF1 AKAP13 RERE FMNL2 SMYD3	1.65e-06	193	83	6	779276e775cb2492e8dd36436295a536084a6415
ToppCell	facs-Liver-Non-hepatocytes-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMPR2 PLXNC1 TMCC2 MACF1 TEK FMNL2	1.65e-06	193	83	6	8084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST ATRX PCLO MACF1 RERE CDH2	1.76e-06	195	83	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST ATRX PCLO MACF1 RERE CDH2	1.76e-06	195	83	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	MYT1L CYRIA DST ATRX PCLO SPTAN1	1.97e-06	199	83	6	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	MYT1L CYRIA DST ATRX PCLO SPTAN1	1.97e-06	199	83	6	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell	Caecum-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	ATP6V0A1 RICTOR LMNB2 F13A1	9.00e-06	70	83	4	05f8fc648641b9db50c2ae20d6246b52869957cf
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	TRAF1 CENPC SYNE1 MACF1 CCDC144A	1.71e-05	171	83	5	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	PCLO CKAP2L E2F1 OTUD3 CFAP65	1.91e-05	175	83	5	fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|368C / Donor, Lineage, Cell class and subclass (all cells)	PCLO CKAP2L E2F1 OTUD3 CFAP65	1.91e-05	175	83	5	36c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	DST SYNE1 SPTAN1 ANKRD26 RICTOR	2.02e-05	177	83	5	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX MACF1 CLIP1 F13A1 DHX9	2.31e-05	182	83	5	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX MACF1 CLIP1 F13A1 DHX9	2.49e-05	185	83	5	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BMPR2 DST ATRX SPTAN1 MACF1	2.83e-05	190	83	5	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 BMPR2 MCC TEK IFIT1	2.83e-05	190	83	5	474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCell	facs-Lung-Endomucin_-18m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMPR2 SYNE1 TMCC2 MCC TEK	2.98e-05	192	83	5	ba3fe97786564dba1c8185f2802ce1b57f4f3cc9
ToppCell	facs-Lung-Endomucin_\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMPR2 SYNE1 TMCC2 MCC TEK	2.98e-05	192	83	5	85d4d0df701451daf95e94a87a0096da1e86533b
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMPR2 MTUS1 TMCC2 MCC TEK	2.98e-05	192	83	5	4bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 MACF1 AKAP13 RERE SMYD3	2.98e-05	192	83	5	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMPR2 SYNE1 TMCC2 MCC TEK	3.05e-05	193	83	5	2218833749576ba1a0fc95bd155c781e7e1163c6
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMPR2 MTUS1 TMCC2 MCC TEK	3.13e-05	194	83	5	f159ef8541d75a4e98468947f231bb463bec922c
ToppCell	COPD-Myeloid-Macrophage\|World / Disease state, Lineage and Cell class	CYRIA RAPGEF1 AKAP13 FMNL2 F13A1	3.13e-05	194	83	5	7d682408e9a6239a4e47befc9376e760cc3d133a
ToppCell	LPS-IL1RA-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BMPR2 DST MCC TEK IFIT1	3.13e-05	194	83	5	43f92b0533e26633dc94cce554045d641ef8fd76
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BMPR2 DST MCC MACF1 TEK	3.13e-05	194	83	5	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	LPS-IL1RA-Endothelial-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BMPR2 DST MCC TEK IFIT1	3.13e-05	194	83	5	1d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-J_(AT1-AT2_progenitors)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	ATRX BRCA2 CKAP2L E2F1 LMNB2	3.13e-05	194	83	5	4d6ae2b25db11a4ae6dadee83be5c8c05b1225c3
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MTUS1 TMCC2 MCC DGKZ FMNL2	3.21e-05	195	83	5	cad21edd90bf3e2fefdf5773a59cb1a664a69ddd
ToppCell	facs-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MTUS1 TMCC2 MCC DGKZ FMNL2	3.21e-05	195	83	5	7e0ef92059ff34e368d2324815f49b50e3ca7332
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMPR2 PLXNC1 MACF1 TEK FMNL2	3.37e-05	197	83	5	deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCell	NS-moderate-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CLUAP1 SYNE1 MLF1 DRC3 CFAP65	3.37e-05	197	83	5	71fea4aa6ce96c7693fa94792d08770622873850
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMPR2 PLXNC1 MACF1 TEK FMNL2	3.37e-05	197	83	5	a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCell	COVID-19_Severe-PLT_0\|COVID-19_Severe / Disease Group and Platelet Clusters	ANXA7 MACF1 E2F1 CLIP1 F13A1	3.37e-05	197	83	5	dbdeefa72d10f2c5f75ad5aac6f31a892d4e94a9
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	URI1 ATRX SYNE1 MACF1 RICTOR	3.45e-05	198	83	5	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	critical-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CLUAP1 SYNE1 MLF1 DRC3 CFAP65	3.45e-05	198	83	5	ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYT1L HECW1 SYNE1 PCLO SPTAN1	3.45e-05	198	83	5	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Severe-B_intermediate-6\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	CYRIA PLXNC1 RAPGEF1 AKAP13 KLK1	3.45e-05	198	83	5	8402421dc060926e968efe39a4e907f1e8ae5b1f
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMPR2 PLXNC1 MACF1 TEK FMNL2	3.45e-05	198	83	5	f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	DST ATRX MTUS1 PCLO CLIP1	3.53e-05	199	83	5	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	Neuron\|World / Primary Cells by Cluster	MYT1L CYRIA ATRX PCLO SPTAN1	3.53e-05	199	83	5	1f8104fd92f04690b41d9d07ac08dc59d76bb97d
ToppCell	Severe-B_intermediate-6\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	CYRIA PLXNC1 RAPGEF1 AKAP13 KLK1	3.53e-05	199	83	5	bf6ebb63ab361d9d1946225894d7be433e9befab
ToppCell	Neuron-Postmitotic\|World / Primary Cells by Cluster	MYT1L CYRIA ATRX PCLO SPTAN1	3.53e-05	199	83	5	1973527f8a7d4c6490d75c0d0ea153688166a08b
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	BRCA2 CENPC CKAP2L E2F1 LMNB2	3.53e-05	199	83	5	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T\|COVID-19_Mild / Disease, condition lineage and cell class	TRAF1 SPTAN1 MACF1 IFIT1 ARHGEF6	3.53e-05	199	83	5	f307d4887b28cf60a591439e278fd668409cb104
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_\|World / Primary Cells by Cluster	MYT1L CYRIA ATRX PCLO SPTAN1	3.53e-05	199	83	5	058373b4ac3cec2108cb24265628ff0a50646e33
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	BMPR2 DST SPTAN1 MACF1 IFIT1	3.62e-05	200	83	5	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	BRCA2 CENPC CKAP2L E2F1 LMNB2	3.62e-05	200	83	5	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	BMPR2 DST SPTAN1 MACF1 IFIT1	3.62e-05	200	83	5	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	LPS_only-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	BMPR2 DST SPTAN1 MACF1 IFIT1	3.62e-05	200	83	5	81e76508c9050d533853d5fd2f3097b27613d836
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	BMPR2 DST SPTAN1 MACF1 TEK	3.62e-05	200	83	5	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	BMPR2 DST SPTAN1 MACF1 IFIT1	3.62e-05	200	83	5	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ATRX CENPC MACF1 AKAP13 IFIT1	3.62e-05	200	83	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	VE\|World / Condition, Cell_class and T cell subcluster	URI1 MKNK2 MACF1 AKAP13 IFIT1	3.62e-05	200	83	5	8ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Cortical_neuron\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	MYT1L CYRIA SYNE1 PCLO SPTAN1	3.62e-05	200	83	5	44bc4d6616fc8d0ad8498e56125939034e8cff01
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	BMPR2 DST SPTAN1 TEK IFIT1	3.62e-05	200	83	5	b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANKRD34B BRCA2 CKAP2L E2F1 LMNB2	3.62e-05	200	83	5	af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	BMPR2 DST SPTAN1 MACF1 IFIT1	3.62e-05	200	83	5	4bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCell	facs-Brain_Myeloid-Cortex_-18m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF1 PLXNC1 E2F1 F13A1	2.07e-04	156	83	4	2ba838bc864c2c1767bcab7bb4d790af96b91387
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	TRAF1 CENPC MACF1 RICTOR	2.07e-04	156	83	4	1545169694f686d28648a68b552c2ae606599d66
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MTUS1 SYNE1 NTRK1 GOLIM4	2.12e-04	157	83	4	0673c7161c25feceee8f1e5fd237171576c42c6b
ToppCell	facs-Marrow-B-cells-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MTUS1 SYNE1 NTRK1 GOLIM4	2.12e-04	157	83	4	d307d0b48af35e0e1af41ecd3ebf91be8fd29dc0
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANKRD34B MTUS1 DRC3 CFAP65	2.27e-04	160	83	4	028b5261a1da832d52f66fb620db83e5fbbd874a
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANKRD34B MTUS1 DRC3 CFAP65	2.27e-04	160	83	4	1f4ee446436726c3d373f56d87dd80b6a12e8b9e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRAF1 CENPC SYDE2 DHX9	2.39e-04	162	83	4	80317c4253bf8e897782e562f29835f181c65b98
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BRCA2 CKAP2L LMNB2 TEK	2.44e-04	163	83	4	5285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell	10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3\|Liver / Manually curated celltypes from each tissue	AKR1E2 DST CEP112 SYDE2	2.44e-04	163	83	4	7f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SPTBN5 BRCA2 NKPD1 E2F1	2.68e-04	167	83	4	108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYNE1 TMCC2 SMYD3 F13A1	2.68e-04	167	83	4	1bd27ffe381d26731b6d4cc5f29b27f1bac4473b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 CKAP2L E2F1 TEK	2.68e-04	167	83	4	bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRAF1 MLF1 GOLIM4 STAMBP	2.74e-04	168	83	4	ca94b29c1030484143a77f2df06dad74d2c6136e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 RAD21L1 CKAP2L E2F1	2.80e-04	169	83	4	121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell	343B-Myeloid-Dendritic-cDC_activated\|343B / Donor, Lineage, Cell class and subclass (all cells)	TRAF1 PLXNC1 CDH2 SPATA32	2.80e-04	169	83	4	2098f15a388d019ed7f1d4c209affd5ca2886dcc
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	URI1 ANXA7 F13A1 DRC3	2.93e-04	171	83	4	d1e87478d8c0329e662849823f5c7604f20e1b1a
ToppCell	normal-na-Lymphocytic_NK-natural_killer_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	MYT1L SPTBN5 SYNE1 TMCC2	2.93e-04	171	83	4	d339840626211a7bf1a9eb8f14d6c9509ab05e1c
ToppCell	droplet-Marrow-nan-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXNC1 SYNE1 GOLIM4 FMNL2	3.00e-04	172	83	4	d354424c1f861b6607dfd63b9724f4c237b30275
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST ATRX MACF1 AKAP13	3.06e-04	173	83	4	869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCell	Leuk-UTI-Myeloid-cDC1\|Leuk-UTI / Disease, Lineage and Cell Type	AKR1E2 DST CEP112 CDH2	3.06e-04	173	83	4	226bb8d881f32d65c60f5e4c034c6d465f8e7ba5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 NKPD1 CKAP2L E2F1	3.06e-04	173	83	4	a25459b8140b0dbcb73e3b4cc1407b679229f25c
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST ATRX MACF1 AKAP13	3.06e-04	173	83	4	0672bd8a4a9d18af343d01f09253fb3388896c10
ToppCell	facs-Brain_Myeloid-Cerebellum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST ATRX MACF1 AKAP13	3.06e-04	173	83	4	870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 CKAP2L E2F1 LMNB2	3.13e-04	174	83	4	c26eac176e9b0cba385630fdc60e0314a4e4caac
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HAUS4 CEP112 CKAP2L LMNB2	3.13e-04	174	83	4	72df66319f6efbd88ecf439013d97409fbf3cb52
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HAUS4 CEP112 CKAP2L LMNB2	3.13e-04	174	83	4	c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRCA2 CENPC MCC ANKRD26	3.20e-04	175	83	4	31f0fb2e47e357dbf9c15436b7df85b3c370ded7
ToppCell	droplet-Lung-21m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CENPC CKAP2L E2F1 ARHGAP35	3.20e-04	175	83	4	6751ee4b312d7f87275f2c35e5878cfc3be3ebe3
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPC CKAP2L CDH2 ARHGEF6	3.20e-04	175	83	4	3e56695a9db97cb1d3503425c48eb79bbf99213e
ToppCell	facs-Marrow-B-cells-18m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEC24D HECW1 CRELD2 CDH2	3.27e-04	176	83	4	5f9ae5eb45603ed0422a3a993ecdbe2ce05d6e45
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	E2F1 CLIP1 SMYD3 F13A1	3.27e-04	176	83	4	1510cdfcfb46ce1196a1220c07fb5f3986c81b78
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYRIA TRAF1 PLXNC1 CCDC144A	3.34e-04	177	83	4	aa56129d2d5a73a10e33b7162233a4d9337ee535
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CLUAP1 BMPR2 MTUS1 NTRK1	3.34e-04	177	83	4	36b5d29caa9cffbc0284f771a4db71aa72171a89
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-Migratory_DCs_L.1.2.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYRIA TRAF1 PLXNC1 CCDC144A	3.34e-04	177	83	4	d78a6003ce2d15d7771ae385de252eec7e3c3eea
ToppCell	367C-Myeloid-Dendritic-cDC_activated\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TRAF1 PCLO TMCC2 CDH2	3.34e-04	177	83	4	a0ff337f11bdb11959ac71805ff94be6b4ec1083
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYRIA TRAF1 PLXNC1 CCDC144A	3.34e-04	177	83	4	70ca5b6fde2e38af1eb88a7d6e8746edba298191
ToppCell	facs-Marrow-B-cells-18m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEC24D HECW1 CRELD2 CDH2	3.34e-04	177	83	4	35d42b07d9c31528bf59199e361bb8a3bfbe3b75
ToppCell	facs-Lung-EPCAM-3m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF1 PLXNC1 KLK1 SPATA32	3.34e-04	177	83	4	d445167dae956e641386f84ab3ae9f47c089e09a
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK1 SMYD3 ARHGEF6 CCDC144A	3.34e-04	177	83	4	86c41d262142eeaa95ea7fa6668169eb1bb2953f
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMPR2 ATRX SYNE1 IFIT1	3.41e-04	178	83	4	01dafd19de04eff459253eaa9a35debf8f3deedf
Drug	Sulfaguanidine [57-67-0]; Down 200; 18.6uM; PC3; HT_HG-U133A	MTUS1 CEP112 PCLO SPTAN1 MLF1 AKAP13 ARHGAP35	7.52e-06	196	83	7	4257_DN
Drug	plakin	SPTBN5 DST SYNE1 SPTAN1 MACF1	1.25e-05	82	83	5	CID000018752
Drug	PRODAN	SPTBN5 SPTAN1 NKPD1	2.06e-05	15	83	3	CID000028127
Drug	geldanamycin; Up 200; 1uM; MCF7; HT_HG-U133A	SEC24D MKNK2 SNAP23 CRELD2 CDH2 IFIT1	3.60e-05	169	83	6	5225_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	CYRIA CEP112 PCLO SPTAN1 MLF1 IFIT1	4.24e-05	174	83	6	6085_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	CYRIA CEP112 PCLO SPTAN1 TMCC2 MLF1	4.66e-05	177	83	6	4821_UP
Drug	trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A	CYRIA CEP112 PCLO TMCC2 MLF1 IFIT1	5.96e-05	185	83	6	5935_UP
Drug	Nifuroxazide [965-52-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A	SRRT ATRX SNAP23 OTUD3 CLIP1 DHX9	6.52e-05	188	83	6	4835_DN
Drug	PF-00562151-00 [351320-12-2]; Up 200; 10uM; MCF7; HT_HG-U133A	SRRT FRAS1 ATP6V0A1 HECW1 TMCC2 SNAP23	7.12e-05	191	83	6	5917_UP
Drug	GSK-3beta Inhibitor VIII; Down 200; 10uM; MCF7; HT_HG-U133A	ANKRD26 SNAP23 E2F1 CCDC57 CLIP1 DHX9	7.32e-05	192	83	6	7092_DN
Drug	Cyproterone acetate [427-51-0]; Down 200; 9.6uM; HL60; HT_HG-U133A	SRRT CYRIA TRAF1 ATP6V0A1 MTUS1 ANKRD26	7.75e-05	194	83	6	6124_DN
Drug	Isoetharine mesylate salt [7279-75-6]; Down 200; 12uM; PC3; HT_HG-U133A	ATRX CEP112 SPTAN1 TMCC2 AKAP13 CDH2	8.21e-05	196	83	6	5812_DN
Drug	Rauwolscine hydrochloride [6211-32-1]; Up 200; 10.2uM; PC3; HT_HG-U133A	SPTBN5 ATP6V0A1 HECW1 PLXNC1 TEK CCDC57	8.21e-05	196	83	6	5800_UP
Drug	Thioperamide maleate [106243-16-7]; Up 200; 9.8uM; HL60; HT_HG-U133A	BMPR2 MTUS1 CEP112 PCLO RERE CLIP1	8.21e-05	196	83	6	3055_UP
Drug	Azathymine, 6 [932-53-6]; Down 200; 31.4uM; MCF7; HT_HG-U133A	BRCA2 POLG E2F1 AKAP13 CLIP1 DHX9	8.21e-05	196	83	6	2827_DN
Drug	sulindac sulfide; Down 200; 50uM; MCF7; HG-U133A	FRAS1 ATP6V0A1 HECW1 MTUS1 TMCC2 E2F1	8.44e-05	197	83	6	308_DN
Drug	Loracarbef [121961-22-6]; Down 200; 10.8uM; HL60; HT_HG-U133A	TRAF1 BMPR2 ATP6V0A1 ATRX RERE DHX9	8.44e-05	197	83	6	2970_DN
Drug	Penbutolol sulfate [38363-32-5]; Down 200; 5.8uM; HL60; HT_HG-U133A	TRAF1 ATP6V0A1 MTUS1 POLG MLF1 IFIT1	8.44e-05	197	83	6	2972_DN
Drug	Xylazine [7361-61-7]; Down 200; 18.2uM; PC3; HT_HG-U133A	SPTBN5 ATP6V0A1 MTUS1 PLXNC1 SYNE1 AKAP13	8.44e-05	197	83	6	4066_DN
Drug	Methoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; HL60; HT_HG-U133A	SPTBN5 CYRIA BMPR2 NTRK1 PCLO RERE	8.44e-05	197	83	6	2488_UP
Drug	Salsolinol hydrobromide [38221-21-5]; Up 200; 15.4uM; MCF7; HT_HG-U133A	SPTBN5 HECW1 TMCC2 E2F1 RERE ARHGAP35	8.68e-05	198	83	6	4816_UP
Drug	Sulfaguanidine [57-67-0]; Up 200; 18.6uM; MCF7; HT_HG-U133A	SPTBN5 HECW1 PCLO TMCC2 RERE CDH2	8.68e-05	198	83	6	4839_UP
Drug	Sulfabenzamide [127-71-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A	BMPR2 ATP6V0A1 POLG SPTAN1 AKAP13 ARHGAP35	8.68e-05	198	83	6	4979_DN
Drug	Dapsone [80-08-0]; Down 200; 16.2uM; HL60; HT_HG-U133A	TRAF1 SPTAN1 TASP1 MLF1 AKAP13 IFIT1	8.68e-05	198	83	6	1868_DN
Drug	Cefotiam hydrochloride; Down 200; 7.2uM; HL60; HT_HG-U133A	CYRIA BMPR2 SPTAN1 MCC RERE ARHGAP35	8.68e-05	198	83	6	2458_DN
Drug	Lidocaone hydrochloride [73-78-9]; Up 200; 14.8uM; MCF7; HT_HG-U133A	SRRT HECW1 ATRX POLG TMCC2 CCDC57	8.68e-05	198	83	6	1499_UP
Drug	Acenocoumarol [152-72-7]; Down 200; 11.4uM; PC3; HT_HG-U133A	SEC24D TRPC4AP ATRX POLG PCLO DHX9	8.68e-05	198	83	6	5878_DN
Drug	Propantheline bromide [50-34-0]; Down 200; 9uM; HL60; HT_HG-U133A	SRRT TRPC4AP BRCA2 PLXNC1 CLIP1 IFIT1	8.68e-05	198	83	6	3013_DN
Drug	Proglumide [6620-60-6]; Up 200; 12uM; HL60; HT_HG-U133A	BMPR2 MTUS1 RERE ARHGAP35 CDH2 KLK1	8.92e-05	199	83	6	2363_UP
Drug	Bupropion hydrochloride [31677-93-7]; Up 200; 14.4uM; MCF7; HT_HG-U133A	SPTBN5 CYRIA ATRX PCLO TMCC2 IFIT1	8.92e-05	199	83	6	6256_UP
Drug	Propylthiouracil [51-52-5]; Up 200; 23.4uM; HL60; HT_HG-U133A	MYT1L CYRIA TRAF1 HECW1 SPTAN1 CCDC57	8.92e-05	199	83	6	2476_UP
Drug	Boldine [476-70-0]; Up 200; 12.2uM; HL60; HT_HG-U133A	CYRIA ATP6V0A1 MTUS1 SPTAN1 TMCC2 CCDC57	9.17e-05	200	83	6	2148_UP
Disease	cholesteryl ester 16:1 measurement	CYRIA CDH2 SMYD3	1.09e-05	16	81	3	EFO_0010342
Disease	lung small cell carcinoma (is_marker_for)	ATRX E2F1 RICTOR	1.09e-05	16	81	3	DOID:5409 (is_marker_for)
Disease	optic disc size measurement	CYRIA RPAP3 RAPGEF1 MACF1 RERE CDH2	2.20e-05	205	81	6	EFO_0004832
Disease	cup-to-disc ratio measurement	FRAS1 MTUS1 RPAP3 RAPGEF1 RERE ARHGAP35 CCDC57 FMNL2	2.42e-05	430	81	8	EFO_0006939
Disease	lung small cell carcinoma (is_implicated_in)	ATRX E2F1 RICTOR	6.21e-05	28	81	3	DOID:5409 (is_implicated_in)
Disease	hereditary sensory neuropathy (implicated_via_orthology)	DST NTRK1	7.40e-05	5	81	2	DOID:0050548 (implicated_via_orthology)
Disease	cerebellar ataxia (is_implicated_in)	SYNE1 POLG	7.40e-05	5	81	2	DOID:0050753 (is_implicated_in)
Disease	3- 4-hydroxyphenyl lactate measurement	CCDC57 CDH2	1.55e-04	7	81	2	EFO_0021008
Disease	Malignant neoplasm of breast	BMPR2 BRCA2 SYNE1 SPTAN1 GOLIM4 MACF1 E2F1 TEK CDH2 CLIP1 CHRND	1.66e-04	1074	81	11	C0006142
Disease	progeria (implicated_via_orthology)	POLG LMNB2	2.06e-04	8	81	2	DOID:3911 (implicated_via_orthology)
Disease	cerebrospinal fluid biomarker measurement, alpha synuclein measurement	CLUAP1 RAPGEF1	3.30e-04	10	81	2	EFO_0006794, EFO_0009323
Disease	Cryptorchidism	ATRX PUM1	3.30e-04	10	81	2	C0010417
Disease	Bipolar Disorder	SRRT BRCA2 SYNE1 NTRK1 POLG PCLO PCNT	3.43e-04	477	81	7	C0005586
Disease	asthma, chronic obstructive pulmonary disease	PLXNC1 RERE CDH2	3.56e-04	50	81	3	EFO_0000341, MONDO_0004979
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 LMNB2	4.83e-04	12	81	2	DOID:11726 (implicated_via_orthology)
Disease	Malignant Glioma	ATRX BRCA2 NTRK1	9.55e-04	70	81	3	C0555198
Disease	mixed gliomas	ATRX BRCA2 NTRK1	9.55e-04	70	81	3	C0259783
Disease	diffuse plaque measurement	MYT1L AKR1E2 PLXNC1 MCC MACF1 RERE SMYD3 F13A1	1.13e-03	758	81	8	EFO_0010699
Disease	cardiomyopathy (is_implicated_in)	POLG KLK1	1.23e-03	19	81	2	DOID:0050700 (is_implicated_in)
Disease	Intellectual Disability	MYT1L SYNE1 MCC MACF1 PUM1 CDH2	1.46e-03	447	81	6	C3714756
Disease	skin hydration measurement	MKNK2 TASP1	1.51e-03	21	81	2	EFO_0009586
Disease	gastric ulcer (biomarker_via_orthology)	TEK F13A1	1.51e-03	21	81	2	DOID:10808 (biomarker_via_orthology)
Disease	Glioma	ATRX BRCA2 NTRK1	1.79e-03	87	81	3	C0017638
Disease	Ovarian Serous Adenocarcinoma	NTRK1 TEK	1.81e-03	23	81	2	C1335177
Disease	Carcinoma of lung	BRCA2 RICTOR	1.81e-03	23	81	2	C0684249
Disease	basal cell carcinoma	CYRIA TRPC4AP BRCA2 TMCC2	1.85e-03	189	81	4	EFO_0004193
Disease	Myocardial Infarction	DGKZ KLK1 F13A1	2.30e-03	95	81	3	C0027051

Protein segments in the cluster

Peptide	Gene	Start	Entry
VNHMRDQNNYNEEKD	CHRND	446	Q07001
TQHSDELEQFMENQG	ARHGEF6	346	Q15052
LESDQREHRMFDQQI	AKAP13	1651	Q12802
LRAANMEHENQIQEF	CEP112	701	Q8N8E3
RDENQSINHQMAQED	ANXA7	331	P20073
QSENMLLRQQLDDVH	CCDC144CP	856	Q8IYA2
SENMLLRQQLDDAHN	ANKRD26	1141	Q9UPS8
DFDTQNMNAIDVSEH	RAD21L1	116	Q9H4I0
MHQNRVASLQEELQD	ANKRD34B	256	A5PLL1
HLDIENEVNNEMANR	CYRIA	171	Q9H0Q0
DFQREAELLTMLQHQ	NTRK1	556	P04629
HSAQVMEDFEERQNA	FRAS1	2956	Q86XX4
FNMSLLENHTRQADE	KLK1	101	P06870
MQLQEQFDNLNAAHE	MTUS1	1031	Q9ULD2
EEALNLAMEFHNSLQ	DST	6591	Q03001
QHNRDLVNFINMFAD	HECW1	1001	Q76N89
MAQALEELRSQHDEQ	LMNB2	256	Q03252
ELNSTELHQMRVQDN	CFAP65	1221	Q6ZU64
IHLMQLSQDYNNEDE	FAM13B	116	Q9NYF5
DESNFNHFLNMTEKQ	FAM83B	181	Q5T0W9
HLLFQQEEERQAQFM	PCLO	3266	Q9Y6V0
IFTEDMHNRDANDKN	PLXNC1	1036	O60486
AMNRQLAQHDEDLAE	MKNK2	401	Q9HBH9
LMQFNHRLTQQEAAE	POLG	966	P54098
SAHDNDANLQMDIFL	F13A1	341	P00488
NALEIELQAQHSMRD	KRT35	321	Q92764
IIHEDFDNNSMSNNI	PRSS54	116	Q6PEW0
SAKHQSEMEDLQNQF	PCNT	366	O95613
NQRQFMDEQAAEREH	PCNT	1476	O95613
LFQDVQFLQMHEEAE	RICTOR	1676	Q6R327
HFFQQIQELNLEMED	MACF1	4256	Q9UPN3
QVRSMDELNHDFQAL	PUM1	121	Q14671
TDFQMLHQDESNKRE	OTUD3	201	Q5T2D3
QLRQQAHYDAMDNDI	GOLIM4	476	O00461
DQQQVERHFTMNELT	ATRX	2191	P46100
QHEVNEDSRSMDQDQ	MCC	121	P23508
RHMAEQDRDFLENEQ	FBF1	1101	Q8TES7
RQLQESEQQLDHLMN	E2F1	211	Q01094
FSEEQLRALNNHRQM	BRCA2	2921	P51587
QDEFQRNSDRNMEEH	CENPC	451	Q03188
HRAQEMLQNQFIGED	BMPR2	841	Q13873
EHEFRLQADNMSNTA	CCDC57	186	Q2TAC2
EKLMEHFRNEDNNID	FMNL2	301	Q96PY5
HFRNEDNNIDFMVAS	FMNL2	306	Q96PY5
LMQEEHDNQANVRSL	IFIT1	81	P09914
ENRQHYQMIQREDQE	DGKZ	911	Q13574
EINQYIDHMQSELDN	DRC3	501	Q9H069
HLQEQDMENSRQVLN	HAUS4	311	Q9H6D7
QSENMLLRQQLDDAH	CCDC144A	1046	A2RUR9
SDFECNQMLEAQEEH	CRELD2	86	Q6UXH1
NVIDMNDNRPEFLHQ	CDH2	256	P19022
MRLDYQHEIENLQNQ	CLIP1	666	P30622
NELMYQLEQDHDLQA	DHX9	366	Q08211
ANQDDELDHETFLMQ	FSCN2	281	O14926
LDMDHTFNIEIENAQ	SYDE2	726	Q5VT97
AQNERCLHMFLQEEA	SNX12	136	Q9UMY4
EEKEDRNTNVNAMHQ	URI1	246	O94763
DALMRVANEESEHNQ	TRPC4AP	336	Q8TEL6
EEQLNDLTELHQNEM	TMCC2	566	O75069
NEESDVDVQLNNRHM	NARS1	221	O43776
DSMEANLNESERQHA	SYNE1	3406	Q8NF91
LEQQRAHELFQAEMF	SYNE1	7491	Q8NF91
MQQEAAQRESEELQH	NKPD1	1	Q17RQ9
MDNLSSEEIQQRAHQ	SNAP23	1	O00161
EMRDDLSQHQIQEEQ	SPATA32	21	Q96LK8
HAQSAELQRLAMEQQ	RERE	1521	Q9P2R6
EMESLQRQFDQDHNL	ARHGAP35	1291	Q9NRY4
FQHFMREEIQDASQL	SMYD3	151	Q9H7B4
MHLDRQQFLNDLRND	SEC24D	666	O94855
FQAELDASMHQQQEL	SPTBN5	2726	Q9NRC6
RQQMQDFFLAHKDEE	SRRT	181	Q9BXP5
ENIQVFDFELTQHDM	AKR1E2	276	Q96JD6
MNNIHVENESLDNFL	CKAP2L	166	Q8IYA6
QQLEDHHRMEQERFE	CLUAP1	271	Q96AJ1
FNDEHQERQEVEMLA	UBN2	166	Q6ZU65
QQAHYDMRRNDDIIN	RAPGEF1	1026	Q13905
QNAEELQDFMRDLEN	RPAP3	16	Q9H6T3
TDMAAHEERVNEVNQ	SPTAN1	196	Q13813
QLEQEQFHAFEEMIR	STAMBP	156	O95630
QFHAFEEMIRNQELE	STAMBP	161	O95630
NQEFINMNESDAHAF	MLF1	181	P58340
TFMLLDQNNREHAID	TRAF1	346	Q13077
TIGRDFEALMNQHQD	TEK	56	Q02763
DDLQMVLNQTEDHRQ	ATP6V0A1	266	Q93050
DNIDHRMVREDLQQD	PXT1	91	Q8NFP0
QAEDAHQALLETMQN	TASP1	311	Q9H6P5
HNTRIMQDTEKDDNN	MYT1L	176	Q9UL68