Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessregulation of receptor-mediated endocytosis

DAB2 USP6 CBLB CLU

4.13e-05156264GO:0048259
DomainDNA/RNA_helicase_DEAH_CS

CHD8 DHX8

9.96e-0435252IPR002464
DomainDEAH_ATP_HELICASE

CHD8 DHX8

1.17e-0338252PS00690
DomainHelicase_C

CHD8 DHX8

8.95e-03107252PF00271
DomainHELICc

CHD8 DHX8

8.95e-03107252SM00490
DomainHelicase_C

CHD8 DHX8

9.11e-03108252IPR001650
DomainHELICASE_CTER

CHD8 DHX8

9.28e-03109252PS51194
DomainHELICASE_ATP_BIND_1

CHD8 DHX8

9.28e-03109252PS51192
DomainDEXDc

CHD8 DHX8

9.28e-03109252SM00487
DomainHelicase_ATP-bd

CHD8 DHX8

9.44e-03110252IPR014001
Pubmed

Genome-wide association study of panic disorder in the Japanese population.

PLEKHG1 CLU

4.17e-051326219165232
Pubmed

Engrailed transcription factors direct excitatory cerebellar neuron diversity and survival.

PLEKHG1 ZFHX3

8.16e-051826238912572
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

HTATSF1 CHD8 NUTF2 MED13L NSUN2 STAG2

8.45e-05101426632416067
Pubmed

Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.

PRAMEF33 PRAMEF10

1.01e-042026226694250
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

DAB2 CHD8 NSUN2 STAG2

1.03e-0433226432786267
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

MLF2 PRAMEF33 PRAMEF10 CPLANE1 STAG2 ATG13

1.22e-04108426611544199
Pubmed

Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.

PRAMEF33 PRAMEF10

1.23e-042226231729367
Pubmed

MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.

PRAMEF33 PRAMEF10

1.60e-042526237451217
Pubmed

Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.

PRAMEF33 PRAMEF10

2.01e-042826225089626
Pubmed

Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.

PRAMEF33 PRAMEF10

2.31e-043026238786026
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

ZFHX3 CHD8 NUTF2 NSUN2 UNC79

2.91e-0480726530575818
Pubmed

Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.

PRAMEF33 PRAMEF10

3.15e-043526219389355
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

HTATSF1 MLF2 CHD8 UNC79

3.86e-0446926427634302
Pubmed

A human MAP kinase interactome.

DAB2 CHD8 CPLANE1 CBLB

4.41e-0448626420936779
Pubmed

DUX is a non-essential synchronizer of zygotic genome activation.

PRAMEF33 PRAMEF10

6.44e-045026231806660
Cytoband9q34.11

CERCAM TOR2A

4.18e-04532629q34.11
Cytoband1p36.21

PRAMEF33 PRAMEF10

5.90e-04632621p36.21
CytobandEnsembl 112 genes in cytogenetic band chr5p13

DAB2 CPLANE1

2.82e-03139262chr5p13
CytobandEnsembl 112 genes in cytogenetic band chr16q22

ZFHX3 NUTF2

4.82e-03183262chr16q22
ToppCellPND14-Immune-Immune_Myeloid-DC-maDC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CERCAM ZNF296 ZFAND4

1.18e-041652631c3709ac9f96ace1f3b28e1f2f15b4a8d65885ca
ToppCellPND14-Immune-Immune_Myeloid-DC-maDC-maDC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CERCAM ZNF296 ZFAND4

1.18e-04165263fbc7d97e6f30975d35c76a7c97947a34cf5975d2
ToppCellsystemic_lupus_erythematosus-flare-Hematopoietic-Progen-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CHD8 UNC79 SLC1A6

1.23e-04167263b89ebd4906f52b1fe6b6540ec9339284e7caddd2
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTATSF1 ZFHX3 CPLANE1

1.25e-04168263d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CERCAM ZNF296 FCHSD1

1.38e-041742637be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CERCAM ZNF296 DHX8

1.38e-04174263ff13a5c55d18b951315908f33cb47c7f9cb901bf
ToppCellnormal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells|normal_Lymph_Node / Location, Cell class and cell subclass

DAB2 USP6 MED13L

1.41e-0417526329fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 PLEKHG1 F8

1.56e-04181263a53f05c4c47465ee62e353716456bd09ab464b23
ToppCellfacs-Thymus-Epithelium-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 PLEKHG1 CLU

1.56e-04181263bce56e12ab93693c9c04fa6aad8f2e1dff0c4d45
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHG1 F8 ZFAND4

1.56e-04181263fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCellfacs-Skin-Anagen-3m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CBLB CLU NSUN2

1.58e-0418226322d6f4790950508e8aa27e02a8133af5f53f13c8
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLEKHG1 CLU F8

1.58e-04182263f231e86524b628e6e11ac33d5c34be99d454a92a
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 PLEKHG1 F8

1.61e-04183263709a486154b3157427deb3b8886b63ac39ea42dd
ToppCelldroplet-Liver-nan-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 PLEKHG1 F8

1.61e-04183263dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCellCOPD-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

PLEKHG1 ZFHX3 MED13L

1.74e-041882631aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

PLEKHG1 ZFHX3 F8

1.79e-04190263a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell(2)_5-FU-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

DAB2 PLEKHG1 F8

1.79e-041902636b391b8a3ffcbdec3acaf242bc52fc3fc9da77c8
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 PLEKHG1 F8

1.82e-0419126388f91e57a1409bdeb91e9bf47510a6fb998a1bf5
ToppCell(1)_Control_(PBS)|World / Stress and Cell class

DAB2 CLU F8

1.82e-04191263b346e13259cb2d506b923ad44b894c21a3eee4c3
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 PLEKHG1 F8

1.82e-041912631924af7d8b0a0b892e480a9fd6d874941b0c0b5d
ToppCellfacs-Skin-Anagen-3m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CBLB CLU NSUN2

1.85e-04192263ec1fd2fb6e71f87189d66261909a84e2be63cacb
ToppCell(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells|(1)_Control_(PBS) / Stress and Cell class

DAB2 PLEKHG1 F8

1.85e-04192263e16e49b302019474232ef4cc0ff217d33afe34cf
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 PLEKHG1 F8

1.85e-04192263d525f7f088a53110912600a7c9f6d33b9270d534
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 PLEKHG1 F8

1.85e-041922632bfac6b3956265205ca47d06888851ed68b65999
ToppCellfacs-Liver-Non-hepatocytes-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 PLEKHG1 F8

1.88e-041932638084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 PLEKHG1 F8

1.91e-04194263c8b9551b93a5aed62154b487db90130604a6125c
ToppCellnucseq-Endothelial-Endothelial_Lymphatic-LEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PLEKHG1 CLU F8

1.91e-04194263f772a9f9ef8635aeaeb8b022dbb94e9672b36ead
ToppCellnucseq-Endothelial-Endothelial_Lymphatic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PLEKHG1 CLU F8

1.91e-041942635d2b3ed5374e2ab10c1c7eb3a03139fc95036a48
ToppCellnucseq-Endothelial-Endothelial_Lymphatic-LEC-LEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PLEKHG1 CLU F8

1.91e-041942633b73f2d305a7566f7ab567e5f18c82cd3d80e32c
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PLEKHG1 CLU F8

1.94e-04195263023e3c97dd3696d74f002ff8da0c04d876c82aef
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 PLEKHG1 F8

1.94e-0419526312ba6d95e42d06b1991b011043c0e3370a7b4131
ToppCell(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

DAB2 PLEKHG1 F8

1.94e-041952636b5d3ecec0c00ebfc889dc6235390ff53b5c0b6a
ToppCellBAL-Mild-cDC_10|Mild / Compartment, Disease Groups and Clusters

PLEKHG1 ZNF296 CBLB

2.00e-04197263c0550d41dd5619b369b590f3d6a61154dd7b2cab
ToppCellproximal-Endothelial-Lymphatic|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PLEKHG1 CLU F8

2.00e-041972638835961bd734a86063fd854cd2fb7028aefb7a72
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 PLEKHG1 F8

2.00e-04197263deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 PLEKHG1 F8

2.00e-04197263d584d0334ea97e3fa8c4cd869f5eeea2c7a1ed04
ToppCellproximal-3-Endothelial-Lymphatic|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PLEKHG1 CLU F8

2.00e-041972631c64e4eb9bfbaf5d6b4349642858f83a00d4d4c6
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 PLEKHG1 F8

2.00e-04197263a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCellproximal-Endothelial-Lymphatic-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PLEKHG1 CLU F8

2.00e-041972638d79e747e344656e2bfc7fe872b4430dca941196
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 PLEKHG1 F8

2.00e-04197263412091994196a06c2779b4c2cfed84be889a5f8d
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLEKHG1 CLU F8

2.00e-04197263e8e879b7634a29569061d3515d180784094a31e7
ToppCell5'-Adult-Appendix-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLEKHG1 CLU F8

2.03e-0419826390e85fe7a0ab376a41666dfff6c0e95b7f1c9475
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2 PLEKHG1 F8

2.03e-04198263f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCellParenchyma_Control_(B.)-Endothelial-TX-Macrophages|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

PLEKHG1 CLU F8

2.09e-04200263d7b89a721988660d8010c804916f5d0ef2520ee2
ToppCellLung_Parenchyma-Control-Myeloid-Macrophage-Macrophages|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PLEKHG1 CLU F8

2.09e-042002631ed1c673184f0c6aae04f90edbb1383b1c1f64d9
ToppCellLung_Parenchyma-Control-Myeloid-Macrophage|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PLEKHG1 CLU F8

2.09e-042002632a1ba87ca4adf351ef8fa2b3154b86a5407b8f2f
ToppCellLung_Parenchyma-Control-Myeloid-Macrophage-Macrophages-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLEKHG1 CLU F8

2.09e-0420026398f6a86fbbe5305c71dae91e7278de9813827935
ToppCell5'-Adult-SmallIntestine-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLEKHG1 CLU F8

2.09e-042002632554b77edfe3d378296b0b25625caacbfb1c0e76
DrugMiconazole [22916-47-8]; Up 200; 9.6uM; PC3; HG-U133A

HTATSF1 MED13L CBLB CLU DHX8

1.92e-061932551896_UP
Diseasepanic disorder

PLEKHG1 CLU

3.02e-0433232EFO_0004262
DiseaseIntellectual Disability

CHD8 MED13L NSUN2 STAG2

3.66e-04447234C3714756
DiseaseAutism Spectrum Disorders

CHD8 NSUN2

1.99e-0385232C1510586
Diseasecortical surface area measurement

PLEKHG1 MLF2 ZFHX3 MED13L ATG13

3.31e-031345235EFO_0010736
Diseasepulse pressure measurement

PLEKHG1 CERCAM ZFHX3 MED13L DHX8

3.83e-031392235EFO_0005763
Diseasebitter alcoholic beverage consumption measurement

MLF2 ZFHX3

4.79e-03133232EFO_0010092
Diseaselung non-small cell carcinoma (is_implicated_in)

ZFHX3 CBLB

5.22e-03139232DOID:3908 (is_implicated_in)
DiseaseMental Retardation, Psychosocial

CHD8 MED13L

5.22e-03139232C0025363
DiseaseProfound Mental Retardation

CHD8 MED13L

5.22e-03139232C0020796
DiseaseMental deficiency

CHD8 MED13L

5.22e-03139232C0917816
Diseasecognitive decline measurement

PLEKHG1 MED13L CBLB

6.16e-03486233EFO_0007710

Protein segments in the cluster

PeptideGeneStartEntry
LPREVFPLMFMEAFS

PRAMEF33

31

A0A0G2JMD5
MFAPKNLELEDTDPM

ATG13

396

O75143
MADPIMDLFDDPNLF

CHD8

1

Q9HCK8
EMLHADMNVPFPEGF

NSUN2

196

Q08J23
DQMDLFGDMSTPPDL

DAB2

211

P98082
NNDDMFVDLPFPDDM

MED13L

2021

Q71F56
PFGMPMLDLDDDDDR

CBLB

441

Q13191
ADEDPIMGFHQMFLL

NUTF2

91

P61970
PDAQNPDMSFFKMLF

F8

1106

P00451
MFHPMDFEDDPLVLN

HTATSF1

271

O43719
DKALDFPGFLDMMAP

FCHSD1

651

Q86WN1
PLDDFDVPFEMLQDD

CPLANE1

2521

Q9H799
DAFMDLIRNMFPPNL

SLC1A6

176

P48664
MLPVDEFLPIMFDQH

CERCAM

496

Q5T4B2
LSFDFMDAPPMETLI

DHX8

941

Q14562
EDPMFLMDPFAIHRQ

MLF2

11

Q15773
SLFLFDEMDKMPPGL

TOR2A

156

Q8N2E6
EPLNFHAMFQPFLEM

CLU

236

P10909
SLFLFDEMDKMPPGL

TOR2A

156

Q5JU69
NEGMDFDTMDIDLPP

STAG2

1186

Q8N3U4
LPREVFPLMFMEAFS

PRAMEF10

31

O60809
LASEMPLMDNPYDLA

PLEKHG1

936

Q9ULL1
MDNRKEPPFFNDDNM

ZFAND4

1

Q86XD8
FLSLPLPMDSYMDLE

USP6

706

P35125
APAANPDDEMEMQDL

ZNF296

16

Q8WUU4
LDRSLDMPFMLFDPS

ZFHX3

2566

Q15911
DMPFMLFDPSNPLLA

ZFHX3

2571

Q15911
MFDIELCPLPFSMEE

UNC79

651

Q9P2D8