Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

TYK2 PIK3R4 FCSK FLT1 CRPPA OAS3 KDR TNKS FGFR4 LRRK1 PFKFB3 PRAG1 TRPT1

2.30e-059387113GO:0016772
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

TYK2 PIK3R4 FCSK FLT1 KDR FGFR4 LRRK1 PFKFB3 PRAG1 TRPT1

1.95e-047097110GO:0016773
GeneOntologyMolecularFunctionvascular endothelial growth factor receptor activity

FLT1 KDR

2.59e-047712GO:0005021
GeneOntologyMolecularFunctionheat shock protein binding

EEF1AKMT3 UNC45B APAF1 KDR NOD2

2.87e-04163715GO:0031072
GeneOntologyMolecularFunctionHsp90 protein binding

UNC45B KDR NOD2

9.90e-0455713GO:0051879
GeneOntologyMolecularFunctionNAD+ nucleotidase, cyclic ADP-ribose generating

TLR2 SARM1

1.45e-0316712GO:0061809
GeneOntologyMolecularFunctionkinase activity

TYK2 PIK3R4 FCSK FLT1 KDR FGFR4 LRRK1 PFKFB3 PRAG1

1.49e-03764719GO:0016301
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

FLT1 KDR FGFR4

1.61e-0365713GO:0004714
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

TYK2 FLT1 KDR FGFR4

1.78e-03145714GO:0004713
GeneOntologyMolecularFunctionpeptidoglycan binding

TLR2 NOD2

2.05e-0319712GO:0042834
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

FLT1 KDR FGFR4

3.45e-0385713GO:0019199
DomainPROTEIN_KINASE_TYR

TYK2 FLT1 KDR FGFR4 PRAG1

2.94e-0597695PS00109
DomainTyr_kinase_AS

TYK2 FLT1 KDR FGFR4 PRAG1

2.94e-0597695IPR008266
DomainTyrKc

TYK2 FLT1 KDR FGFR4

3.15e-0488694SM00219
DomainTyr_kinase_cat_dom

TYK2 FLT1 KDR FGFR4

3.15e-0488694IPR020635
DomainTyr_kinase_rcpt_3_CS

FLT1 KDR

3.71e-048692IPR001824
DomainRECEPTOR_TYR_KIN_III

FLT1 KDR

3.71e-048692PS00240
DomainAnk_3

ASB18 TNKS

5.94e-0410692PF13606
DomainP-loop_NTPase

DNHD1 ABCC3 MYH3 MYH8 SPEF2 APAF1 SHPRH LRRK1 PFKFB3 NOD2

1.06e-038486910IPR027417
DomainPkinase_Tyr

TYK2 FLT1 KDR FGFR4

1.33e-03129694PF07714
DomainMyosin_N

MYH3 MYH8

1.37e-0315692PF02736
DomainMyosin_N

MYH3 MYH8

1.37e-0315692IPR004009
Domain-

MON2 PIK3R4 UNC45B SARM1 CUL9

1.37e-032226951.25.10.10
DomainAnk

ASB18 KANK4 TNKS LRRK1 ANKRD55

1.55e-03228695PF00023
DomainARM-type_fold

MON2 PIK3R4 THADA UNC45B SARM1 CUL9

1.57e-03339696IPR016024
DomainSer-Thr/Tyr_kinase_cat_dom

TYK2 FLT1 KDR FGFR4

1.70e-03138694IPR001245
DomainMyosin_tail_1

MYH3 MYH8

1.98e-0318692PF01576
DomainMyosin_tail

MYH3 MYH8

1.98e-0318692IPR002928
DomainProt_kinase_dom

TYK2 PIK3R4 FLT1 KDR FGFR4 LRRK1 PRAG1

2.15e-03489697IPR000719
DomainMyosin-like_IQ_dom

MYH3 MYH8

2.21e-0319692IPR027401
Domain-

MYH3 MYH8

2.21e-03196924.10.270.10
Domain-

ASB18 KANK4 TNKS LRRK1 ANKRD55

2.23e-032486951.25.40.20
DomainPROTEIN_KINASE_DOM

TYK2 PIK3R4 FLT1 KDR FGFR4 LRRK1 PRAG1

2.25e-03493697PS50011
DomainANK

ASB18 KANK4 TNKS LRRK1 ANKRD55

2.35e-03251695SM00248
DomainANK_REPEAT

ASB18 KANK4 TNKS LRRK1 ANKRD55

2.43e-03253695PS50088
DomainAnkyrin_rpt-contain_dom

ASB18 KANK4 TNKS LRRK1 ANKRD55

2.48e-03254695IPR020683
DomainANK_REP_REGION

ASB18 KANK4 TNKS LRRK1 ANKRD55

2.48e-03254695PS50297
DomainTIR

TLR2 SARM1

2.70e-0321692SM00255
DomainAnkyrin_rpt

ASB18 KANK4 TNKS LRRK1 ANKRD55

2.83e-03262695IPR002110
DomainARM-like

MON2 PIK3R4 UNC45B SARM1 CUL9

3.22e-03270695IPR011989
Domain-

TLR2 SARM1

3.24e-03236923.40.50.10140
DomainWGR_domain

TNKS TRPT1

3.52e-0324692IPR008893
DomainTIR

TLR2 SARM1

3.52e-0324692PS50104
DomainKinase-like_dom

TYK2 PIK3R4 FLT1 KDR FGFR4 LRRK1 PRAG1

3.80e-03542697IPR011009
DomainTIR_dom

TLR2 SARM1

3.82e-0325692IPR000157
DomainCARD

APAF1 NOD2

4.78e-0328692PF00619
DomainGalactose-bd-like

CUL9 UBOX5 F5

5.09e-0394693IPR008979
DomainCARD

APAF1 NOD2

5.84e-0331692IPR001315
Domain-

DNHD1 ABCC3 SPEF2 APAF1 SHPRH LRRK1 PFKFB3 NOD2

6.08e-037466983.40.50.300
DomainCARD

APAF1 NOD2

6.60e-0333692PS50209
DomainPROTEIN_KINASE_ATP

TYK2 PIK3R4 FLT1 KDR FGFR4 LRRK1

6.93e-03459696PS00107
DomainAnk_2

ASB18 TNKS LRRK1 ANKRD55

8.24e-03215694PF12796
DomainMyosin_head_motor_dom

MYH3 MYH8

8.68e-0338692IPR001609
Pubmed

Identification of novel protein kinases expressed in the myocardium of the developing mouse heart.

TYK2 FLT1 KDR FGFR4

7.98e-08207247893599
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MON2 TYK2 ABCC3 THADA SH3TC1 CUL9 ZFYVE26 LRRK1 TNRC6C PRAG1 SH2B2 ADCY9 NOD2

3.91e-071105721335748872
Pubmed

Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium.

FLT1 KDR

4.23e-0627228356051
Pubmed

Vascular endothelial growth factor and its receptors in normal human testicular tissue.

FLT1 KDR

4.23e-0627229256359
Pubmed

Expression of vascular endothelial growth factor receptors in the endometrium of septate uterus.

FLT1 KDR

4.23e-06272219200976
Pubmed

Production of VEGF receptor 1 and 2 mRNA and protein during endochondral bone repair is differential and healing phase specific.

FLT1 KDR

4.23e-06272220947709
Pubmed

NOD2 mediates anti-inflammatory signals induced by TLR2 ligands: implications for Crohn's disease.

TLR2 NOD2

4.23e-06272215214053
Pubmed

Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice.

FLT1 KDR

4.23e-06272215852018
Pubmed

VEGFR1 and VEGFR2 in lip carcinogenesis and its association with microvessel density.

FLT1 KDR

4.23e-06272225895461
Pubmed

Recognition of Borrelia burgdorferi by NOD2 is central for the induction of an inflammatory reaction.

TLR2 NOD2

4.23e-06272220441518
Pubmed

VEGFR1 and VEGFR2 in Alzheimer's Disease.

FLT1 KDR

4.23e-06272229226875
Pubmed

Blockade of VEGFR1 and 2 suppresses pathological angiogenesis and vascular leakage in the eye.

FLT1 KDR

4.23e-06272221731737
Pubmed

Expression of VEGF receptors on endothelial cells in mouse skeletal muscle.

FLT1 KDR

4.23e-06272222984559
Pubmed

Differential expression of the two VEGF receptors flt and KDR in placenta and vascular endothelial cells.

FLT1 KDR

4.23e-0627228126087
Pubmed

Quantitative assessment and clinical relevance of VEGFRs-positive tumor cells in refractory brain tumors.

FLT1 KDR

4.23e-06272232088190
Pubmed

Expression of vascular endothelial growth factor receptors during male germ cell differentiation in the mouse.

FLT1 KDR

4.23e-06272212773425
Pubmed

VEGF receptor blockade markedly reduces retinal microglia/macrophage infiltration into laser-induced CNV.

FLT1 KDR

4.23e-06272223977149
Pubmed

Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation.

FLT1 KDR

4.23e-06272215611243
Pubmed

Bacterial peptidoglycan breaks down intestinal tolerance via mast cell activation: the role of TLR2 and NOD2.

TLR2 NOD2

4.23e-06272217563761
Pubmed

GPR126 protein regulates developmental and pathological angiogenesis through modulation of VEGFR2 receptor signaling.

KDR ADGRG6

4.23e-06272225217645
Pubmed

Inhibition of prostate cancer osteoblastic progression with VEGF121/rGel, a single agent targeting osteoblasts, osteoclasts, and tumor neovasculature.

FLT1 KDR

4.23e-06272221343372
Pubmed

Selected angiogenic cytokines in systemic lupus erythematosus patients.

FLT1 KDR

4.23e-06272219811263
Pubmed

Flt1 and Flk1 mediate regulation of intraocular pressure and their double heterozygosity causes the buphthalmia in mice.

FLT1 KDR

4.23e-06272222426483
Pubmed

VEGFR1 tyrosine kinase signaling promotes lymphangiogenesis as well as angiogenesis indirectly via macrophage recruitment.

FLT1 KDR

4.23e-06272218174461
Pubmed

The effects of VEGF-R1 and VEGF-R2 ligands on angiogenic responses and left ventricular function in mice.

FLT1 KDR

4.23e-06272219955220
Pubmed

Involvement of VEGFR-2 (kdr/flk-1) but not VEGFR-1 (flt-1) in VEGF-A and VEGF-C-induced tube formation by human microvascular endothelial cells in fibrin matrices in vitro.

FLT1 KDR

4.23e-06272211824379
Pubmed

Herbal compound farnesiferol C exerts antiangiogenic and antitumor activity and targets multiple aspects of VEGFR1 (Flt1) or VEGFR2 (Flk1) signaling cascades.

FLT1 KDR

4.23e-06272220103598
Pubmed

Quantitative real-time reverse transcription PCR study of the expression of vascular endothelial growth factor (VEGF) splice variants and VEGF receptors (VEGFR-1 and VEGFR-2) in non small cell lung cancer.

FLT1 KDR

4.23e-06272217599955
Pubmed

Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival.

FLT1 KDR

4.23e-06272216793887
Pubmed

The soluble VEGF receptor 1 and 2 expression in cerebral spinal fluid as an indicator for leukemia central nervous system metastasis.

FLT1 KDR

4.23e-06272223400753
Pubmed

NOD2 and TLR2 ligands trigger the activation of basophils and eosinophils by interacting with dermal fibroblasts in atopic dermatitis-like skin inflammation.

TLR2 NOD2

4.23e-06272226388234
Pubmed

Butyrate mediates nucleotide-binding and oligomerisation domain (NOD) 2-dependent mucosal immune responses against peptidoglycan.

TLR2 NOD2

4.23e-06272219830732
Pubmed

Endothelial progenitor cells induce transplant arteriosclerosis via VEGFR-1/2 activity.

FLT1 KDR

4.23e-06272225437886
Pubmed

Invasive Streptococcus mutans induces inflammatory cytokine production in human aortic endothelial cells via regulation of intracellular toll-like receptor 2 and nucleotide-binding oligomerization domain 2.

TLR2 NOD2

4.23e-06272227004566
Pubmed

Nucleotide-binding oligomerization domain 2 and Toll-like receptor 2 function independently in a murine model of arthritis triggered by intraarticular peptidoglycan.

TLR2 NOD2

4.23e-06272220131263
Pubmed

Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia.

FLT1 KDR

4.23e-0627229295307
Pubmed

Trophoblast expression of fms-like tyrosine kinase 1 is not required for the establishment of the maternal-fetal interface in the mouse placenta.

FLT1 KDR

4.23e-06272214668430
Pubmed

Endothelial cell-by-cell profiling reveals the temporal dynamics of VEGFR1 and VEGFR2 membrane localization after murine hindlimb ischemia.

FLT1 KDR

4.23e-06272223376830
Pubmed

Expression of vascular endothelial growth factor receptor-1/-2 and nitric oxide in unruptured intracranial aneurysms.

FLT1 KDR

4.23e-06272220635108
Pubmed

Hypoxia differentially regulates VEGFR1 and VEGFR2 levels and alters intracellular signaling and cell migration in endothelial cells.

FLT1 KDR

4.23e-06272221168388
Pubmed

Distinct expression patterns of Flk1 and Flt1 in the coronary vascular system during development and after myocardial infarction.

FLT1 KDR

4.23e-06272229158084
Pubmed

Signaling via pattern recognition receptors NOD2 and TLR2 contributes to immunomodulatory control of lethal pneumovirus infection.

TLR2 NOD2

4.23e-06272227312104
Pubmed

Staphylococcal peptidoglycan co-localizes with Nod2 and TLR2 and activates innate immune response via both receptors in primary murine keratinocytes.

TLR2 NOD2

4.23e-06272220949035
Pubmed

Vascular endothelial growth factor-induced genes in human umbilical vein endothelial cells: relative roles of KDR and Flt-1 receptors.

FLT1 KDR

4.23e-06272212426207
Pubmed

Randomized Phase II Study of Ramucirumab or Icrucumab in Combination with Capecitabine in Patients with Previously Treated Locally Advanced or Metastatic Breast Cancer.

FLT1 KDR

4.23e-06272228220020
Pubmed

Comparative study of human colonic tumor-derived endothelial cells (HCTEC) and normal colonic microvascular endothelial cells (HCMEC): Hypoxia-induced sVEGFR-1 and sVEGFR-2 levels.

FLT1 KDR

4.23e-06272219287991
Pubmed

Immunohistochemical expression of vascular endothelial growth factor A (VEGF), and its receptors (VEGFR1, 2) in normal and pathologic conditions of the human thymus.

FLT1 KDR

4.23e-06272218356031
Pubmed

The role of heterodimerization between VEGFR-1 and VEGFR-2 in the regulation of endothelial cell homeostasis.

FLT1 KDR

4.23e-06272222828632
Pubmed

Suppression of migratory and metastatic pathways via blocking VEGFR1 and VEGFR2.

FLT1 KDR

4.23e-06272230929546
Pubmed

Proangiogenic Effect of Metformin in Endothelial Cells Is via Upregulation of VEGFR1/2 and Their Signaling under Hyperglycemia-Hypoxia.

FLT1 KDR

4.23e-06272229351188
Pubmed

Comparative structure-function analysis of VEGFR-1 and VEGFR-2: What have we learned from chimeric systems?

FLT1 KDR

4.23e-06272212814952
Pubmed

In vivo regulation of mRNA expression of vascular endothelial growth factor receptors (KDR and flt-1) in the human oviduct.

FLT1 KDR

4.23e-06272214967383
Pubmed

Blockade of VEGFR2 and not VEGFR1 can limit diet-induced fat tissue expansion: role of local versus bone marrow-derived endothelial cells.

FLT1 KDR

4.23e-06272219333381
Pubmed

Nod2 deficiency impairs inflammatory and epithelial aspects of the cutaneous wound-healing response.

TLR2 NOD2

4.23e-06272222951952
Pubmed

Hypoxia-induced reduction of sVEGFR-2 levels in human colonic microvascular endothelial cells in vitro: Comparative study with HUVEC.

FLT1 KDR

4.23e-06272219082506
Pubmed

VEGFR1 and VEGFR2 immunohistochemical expression in oral squamous cell carcinoma: a morphometric study.

FLT1 KDR

4.23e-06272222203933
Pubmed

Absence of mutations in the activation loop and juxtamembrane domains of VEGFR-1 and VEGFR-2 gene in chronic myelomonocytic leukemia (CMML).

FLT1 KDR

4.23e-06272222153185
Pubmed

Angiogenesis in systemic sclerosis: impaired expression of vascular endothelial growth factor receptor 1 in endothelial progenitor-derived cells under hypoxic conditions.

FLT1 KDR

4.23e-06272218975312
Pubmed

Soluble forms of VEGF receptor-1 and -2 promote vascular maturation via mural cell recruitment.

FLT1 KDR

4.23e-06272220484670
Pubmed

The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branching.

FLT1 KDR

4.23e-06272218504303
Pubmed

Evidence in support of a role for anti-angiogenic factors in preterm prelabor rupture of membranes.

FLT1 KDR

4.23e-06272220158393
Pubmed

Nod2 suppresses Borrelia burgdorferi mediated murine Lyme arthritis and carditis through the induction of tolerance.

TLR2 NOD2

4.23e-06272221387014
Pubmed

Expression of vascular endothelial growth factor receptors is closely related to the histological grade of hepatocellular carcinoma.

FLT1 KDR

4.23e-06272216786116
Pubmed

A cyclic peptide reproducing the α1 helix of VEGF-B binds to VEGFR-1 and VEGFR-2 and inhibits angiogenesis and tumor growth.

FLT1 KDR

4.23e-06272230700502
Pubmed

Aberrant Expression of Bacterial Pattern Recognition Receptor NOD2 of Basophils and Microbicidal Peptides in Atopic Dermatitis.

TLR2 NOD2

4.23e-06272227077833
Pubmed

Bone formation during distraction osteogenesis is dependent on both VEGFR1 and VEGFR2 signaling.

FLT1 KDR

4.23e-06272218433297
Pubmed

The vascular endothelial growth factor (VEGF) receptor Flt-1 (VEGFR-1) modulates Flk-1 (VEGFR-2) signaling during blood vessel formation.

FLT1 KDR

4.23e-06272215111299
Pubmed

The crosstalk between TLR2 and NOD2 in Aspergillus fumigatus keratitis.

TLR2 NOD2

4.23e-06272225549945
Pubmed

Increased expression of KDR/Flk-1 (VEGFR-2) in murine model of ischemia-induced retinal neovascularization.

FLT1 KDR

4.23e-0627229828156
Pubmed

Bovine papular stomatitis virus encodes a functionally distinct VEGF that binds both VEGFR-1 and VEGFR-2.

FLT1 KDR

4.23e-06272217325350
Pubmed

Phase III Trial of Adjuvant Sunitinib in Patients with High-Risk Renal Cell Carcinoma: Exploratory Pharmacogenomic Analysis.

FLT1 KDR

4.23e-06272230401688
Pubmed

Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells.

FLT1 KDR

4.23e-06272219265665
Pubmed

Toll-like receptor 2 and nucleotide-binding oligomerization domain-2 play divergent roles in the recognition of gut-derived lactobacilli and bifidobacteria in dendritic cells.

TLR2 NOD2

4.23e-06272218217947
Pubmed

VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia.

FLT1 KDR

4.23e-06272214996703
Pubmed

Distinct roles of VEGFR-1 and VEGFR-2 in the aberrant hematopoiesis associated with elevated levels of VEGF.

FLT1 KDR

4.23e-06272217376891
Pubmed

Vascular endothelial growth factor and its soluble receptors VEGFR-1 and VEGFR-2 in the serum of patients with systemic lupus erythematosus.

FLT1 KDR

4.23e-06272214760936
Pubmed

DC electric stimulation upregulates angiogenic factors in endothelial cells through activation of VEGF receptors.

FLT1 KDR

4.23e-06272221524919
Pubmed

VEGFR1 and VEGFR2 involvement in extracellular galectin-1- and galectin-3-induced angiogenesis.

FLT1 KDR

4.23e-06272223799140
Pubmed

VEGFR2-mediated vascular dilation as a mechanism of VEGF-induced anemia and bone marrow cell mobilization.

FLT1 KDR

4.23e-06272225310988
Pubmed

Inhibition of VEGF receptors significantly impairs mammary cancer growth in C3(1)/Tag transgenic mice through antiangiogenic and non-antiangiogenic mechanisms.

FLT1 KDR

4.23e-06272215592523
Pubmed

The Staphylococcus aureus lipoprotein SitC colocalizes with Toll-like receptor 2 (TLR2) in murine keratinocytes and elicits intracellular TLR2 accumulation.

TLR2 NOD2

4.23e-06272220679445
Pubmed

Morphine inhibits murine dendritic cell IL-23 production by modulating Toll-like receptor 2 and Nod2 signaling.

TLR2 NOD2

4.23e-06272221245149
Pubmed

Identification of functional VEGF receptors on human platelets.

FLT1 KDR

4.23e-06272211852061
Pubmed

Expression of vascular endothelial growth factor and its receptors in hematopoietic malignancies.

FLT1 KDR

4.23e-0627229973224
Pubmed

Distinct roles of vascular endothelial growth factor receptor-1- and receptor-2-mediated signaling in T cell priming and Th17 polarization to lipopolysaccharide-containing allergens in the lung.

FLT1 KDR

4.23e-06272220921519
Pubmed

TLR2 and Nod2 mediate resistance or susceptibility to fatal intracellular Ehrlichia infection in murine models of ehrlichiosis.

TLR2 NOD2

4.23e-06272223526993
Pubmed

Nucleotide-binding oligomerization domain protein 2-deficient mice control infection with Mycobacterium tuberculosis.

TLR2 NOD2

4.23e-06272217709422
Pubmed

Prognostic significance of VEGF receptors expression on the tumor cells in skull base chordoma.

FLT1 KDR

4.23e-06272231240525
Pubmed

The Prognostic Value of the Combination of Low VEGFR-1 and High VEGFR-2 Expression in Endothelial Cells of Colorectal Cancer.

FLT1 KDR

4.23e-06272230423986
Pubmed

Properties of two VEGF receptors, Flt-1 and KDR, in signal transduction.

FLT1 KDR

4.23e-06272210865839
Pubmed

Retinal astrocytes pretreated with NOD2 and TLR2 ligands activate uveitogenic T cells.

TLR2 NOD2

4.23e-06272222808176
Pubmed

Inhibition of Vascular Endothelial Growth Factor Receptors 1 and 2 Attenuates Natural Killer Cell and Innate Immune Responses in an Experimental Model for Obliterative Bronchiolitis.

FLT1 KDR

4.23e-06272234774518
Pubmed

Attenuation of VEGFR-2 expression by sFlt-1 and low oxygen in human placenta.

FLT1 KDR

4.23e-06272224260556
Pubmed

Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects.

FLT1 KDR HBB

6.79e-061872312093914
Pubmed

Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development.

FLT1 KDR HBB

8.05e-061972316787915
Pubmed

MARCO is required for TLR2- and Nod2-mediated responses to Streptococcus pneumoniae and clearance of pneumococcal colonization in the murine nasopharynx.

TLR2 NOD2

1.27e-05372223197261
Pubmed

Early endocardial morphogenesis requires Scl/Tal1.

FLT1 KDR

1.27e-05372217722983
Pubmed

The expression of VEGF receptor genes is concurrently influenced by epigenetic gene silencing of the genes and VEGF activation.

FLT1 KDR

1.27e-05372219633424
Pubmed

Analysis of circulating vascular endothelial growth factor and its soluble receptors in patients with different forms of chronic urticaria.

FLT1 KDR

1.27e-05372225756047
Pubmed

Vascular endothelial growth factor isoform and receptor expression during compensatory lung growth.

FLT1 KDR

1.27e-05372219535097
GeneFamilyReceptor Tyrosine Kinases|CD molecules

FLT1 KDR FGFR4

1.43e-0440463321
GeneFamilyMyosin heavy chains

MYH3 MYH8

6.51e-04154621098
GeneFamilyWD repeat domain containing|Caspase recruitment domain containing|Apoptosome

APAF1 NOD2

2.63e-0330462959
GeneFamilyAnkyrin repeat domain containing

ASB18 KANK4 TNKS ANKRD55

3.29e-03242464403
ToppCellfacs-MAT-Fat-18m-Endothelial|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KANK4 KDR PRAG1 ITPRIPL1

6.50e-0719072634e56c5e7ea6a8f227dbaefe73cbb8818d18b523
ToppCellfacs-MAT-Fat-18m-Endothelial-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KANK4 KDR PRAG1 ITPRIPL1

6.50e-0719072614cdb660ad3aabcf49572173e7628d8b99dcbe6f
ToppCellfacs-MAT-Fat-18m-Endothelial-endothelial_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KANK4 KDR PRAG1 ITPRIPL1

6.50e-071907269aaa48f3aad813c87a45efdbb67d255c94f6e6a4
ToppCellLPS-antiTNF-Endothelial-Endothelial-Vein|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT1 SPEF2 IL4I1 F5 SH2B2 ADGRG6

6.90e-0719272681baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCell(08)_PNEC-(2)_48hpi|(08)_PNEC / shred by cell type and Timepoint

RHCG CLCN5 ENPP1 OAS3 KDR

3.44e-06142725e95d34170f5053678e0dd9793e68d93c03b05822
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FLT1 SH3TC1 UNC45B KDR ST6GALNAC2

5.12e-06154725b0735365de153d4586ca17896431d7bd9c7d8eac
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Cilia-bearing_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

SPEF2 CRPPA ROM1 METAP1D UBOX5

6.95e-06164725346e1530b4bf30adbcb2f7d64fdfb4cd8df69d7f
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLT1 UNC45B KDR PFKFB3 ST6GALNAC2

9.27e-0617472540bb87d219aafab0357ab0d797efd38085fc0312
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_2|356C / Donor, Lineage, Cell class and subclass (all cells)

EEF1AKMT3 ROM1 TNRC6C F5 VCPIP1

1.03e-051787258b939659f713eea50a1a6e28b571f680ca0b4c12
ToppCellmild_COVID-19_(asymptomatic)-cDC|World / disease group, cell group and cell class (v2)

ASB18 OAS3 IL4I1 ADGRG6 NOD2

1.09e-0518072568d1c867734fb2977b01ac686b20bf602f9a6b72
ToppCellfacs-GAT-Fat-24m-Endothelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR PRAG1 ST6GALNAC2

1.42e-05190725da2fcd4a2cc6e45c8174109d892f1424e39919a1
ToppCellfacs-GAT-Fat-24m-Endothelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR PRAG1 ST6GALNAC2

1.42e-051907253395b2ff6ffadf84cdb1b5a37a5b6be05b56c30f
ToppCellfacs-SCAT-Fat-18m-Endothelial-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR PRAG1 ITPRIPL1

1.42e-05190725b0c9dae8189d407c94964c6bfe3ef92035245357
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR PFKFB3 NOD2

1.42e-0519072538a815abf0ac5cac6071737cadc54a514f62d37d
ToppCellfacs-SCAT-Fat-18m-Endothelial|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR PRAG1 ITPRIPL1

1.42e-05190725ee63dc04e91ad49aa7820c98e97261176ecebaa6
ToppCellfacs-GAT-Fat-24m-Endothelial-endothelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR PRAG1 ST6GALNAC2

1.42e-05190725e584eaccbc22aa7f7a4340ed8a2a8b45ddca93f4
ToppCellfacs-SCAT-Fat-18m-Endothelial-endothelial_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR PRAG1 ITPRIPL1

1.42e-051907250e50808bfc3d0820524c8470ae3e8250819d65b2
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR PFKFB3 NOD2

1.42e-05190725bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR PFKFB3 NOD2

1.42e-05190725d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLT1 UNC45B KDR PFKFB3 NOD2

1.42e-051907252655df8c0883dd811fa7617301f9c4b0a4dd55ec
ToppCelldroplet-Fat-Gat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR PRAG1 ST6GALNAC2

1.49e-05192725c312e39003c51503c9f648332fb5c6218f33f99b
ToppCelldroplet-Fat-Gat-18m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR PRAG1 ST6GALNAC2

1.49e-05192725df09056f0e562f53b6fb30b674d2d83e9eb857d0
ToppCelldroplet-Fat-Gat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR PRAG1 ST6GALNAC2

1.49e-05192725133b3ad251d72ff31e45e1dc6217945516ac63de
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT1 IL4I1 F5 SH2B2 ADGRG6

1.53e-051937257261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCell367C-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ENPP1 PFKFB3 ITPRIPL1 ADGRG6 VCPIP1

1.61e-05195725fca958f73de450ef813444d3dc590353f1c55326
ToppCellBronchial-10x5prime-Immune_Myeloid-Macrophage_other-Macro_interstitial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TLR2 OAS3 PFKFB3 IL4I1 NOD2

1.69e-051977251a30747a2188a890f58d831030328986b3a4356d
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Vein|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FLT1 IL4I1 F5 SH2B2 ADGRG6

1.77e-05199725cfb624c7728046fc7f3ef071f57e4d7b013f3fef
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

FLT1 OAS3 KDR IL4I1 SH2B2

1.81e-05200725edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHCG CUL9 METAP1D HDAC10

4.74e-05123724a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_STALK|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FLT1 SH3TC1 UNC45B ST6GALNAC2

6.06e-05131724308ddb7fe113eac5dbeb9cb0b688d9e09275ce5e
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FLT1 SH3TC1 UNC45B ST6GALNAC2

6.24e-0513272406e7337de35bd7120655a22b6020604ad004c4e1
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

FLT1 UNC45B ST6GALNAC2 NOD2

6.43e-05133724bc29a2faa151b0e48c1c7e3f016cccc49f9a15eb
ToppCell356C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FCSK SH3TC1 CRPPA HDAC10

7.01e-05136724edfd453c9a650d69d05a5a3ab15f7df56349fa86
ToppCell356C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FCSK SH3TC1 CRPPA HDAC10

7.01e-0513672403e4e2353c23ceffde35b2d0aadd15299e3db09f
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma_Heterologous_Type-4|TCGA-Uterus / Sample_Type by Project: Shred V9

MYH3 MYH8 FBXO10 UNC45B

7.41e-05138724d1104a9f751ffa6970fd3096a4abf5bed30aa78f
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_STALK|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

FLT1 SH3TC1 UNC45B ST6GALNAC2

8.51e-0514372435d3652680c4dddd293301595d813161c66e5673
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FLT1 SH3TC1 UNC45B ST6GALNAC2

8.74e-051447241c118b22c2ff3a526a5207d6c9d772636ee065fd
ToppCellTCGA-Uterus|World / Sample_Type by Project: Shred V9

MYH3 MYH8 UNC45B KANK4

8.74e-051447247efb45286ebf2dbfb9125fd6373f28dccb029a2e
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FLT1 SH3TC1 UNC45B ST6GALNAC2

9.98e-05149724d9c47f523c75ddcd6131e45d2ffc24b970932cae
ToppCell10x3'2.3-week_12-13-Hematopoietic-HSC/MPP_and_pro-eo/baso/mast_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MYH3 CRPPA TTC34 SLC27A2

9.98e-05149724797b5f267e86fbe1d7af99df514d8074446603c6
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ENPP1 DHDDS KDR TNRC6C

1.08e-041527240652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RHCG ABCC3 CRPPA SLC27A2

1.16e-041557245fabe24a784f0be46040ffc886eabd8d5ce78121
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK|Thalamus / BrainAtlas - Mouse McCarroll V32

FLT1 SH3TC1 UNC45B ST6GALNAC2

1.16e-04155724fe6c4aba0e98cda84bf178aeac2e9fa834477f22
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLT1 UNC45B KDR FAM187A

1.25e-0415872478b48b110b777bcc4c07cd23388bee911c0231d6
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Granulocytic|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TLR2 PFKFB3 F5 NOD2

1.31e-041607243b5a335786165391fe983ff0585cd508733793aa
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TLR2 PFKFB3 F5 NOD2

1.31e-041607242586035a1380bc56814a6db0ca773ad835666042
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_STALK|Entopeduncular / BrainAtlas - Mouse McCarroll V32

SH3TC1 UNC45B ITPRIPL1 ST6GALNAC2

1.31e-0416072404714d0b9bad4c11fa193ed168e2d84a4df39e2e
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FLT1 UNC45B KDR ST6GALNAC2

1.34e-04161724a60ef3f390f56bb05b687b17986fe6382f69f260
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell-Endo|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FLT1 UNC45B KDR ST6GALNAC2

1.38e-041627240bdb1e5ba33e162bec1acb28256c1405a7658ee5
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tregs|GI_large-bowel / Manually curated celltypes from each tissue

THADA SH3TC1 F5 ANKRD55

1.38e-041627249a5e65c45f73a6a685b8362aa2e6aea77181caa3
ToppCellT_cells-Tph_and_Tfh|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

FLT1 THADA ANKRD55 SLC27A2

1.38e-04162724146058f2d60846376078916055d08f68562e3a7c
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FLT1 UNC45B KDR ST6GALNAC2

1.38e-041627245799a602ef8d83925907e8e34532428be7330228
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FLT1 UNC45B KDR ST6GALNAC2

1.44e-041647246a41a159134e605b80d5e731f9ed5bc803bb531b
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RHCG SPEF2 KANK4 SLC27A2

1.44e-041647243caf4cdaa0164907893fea61e251fd8b5fa926e4
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FLT1 UNC45B KDR ST6GALNAC2

1.44e-04164724ec68954fc09b6850273b5e59caa6b09d02151097
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ASB18 MYH8 ENPP1 PRAG1

1.44e-04164724382e42701779d12a7948690b3be72d06dd75c8b4
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MTHFD2L OAS3 MTX1 NOD2

1.48e-04165724436ce4bc75e1ba4351c439ccad19f84ad5bcb92f
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MTHFD2L OAS3 MTX1 NOD2

1.48e-04165724242bdb7654f415391fb8e9bdc06412c7eee9c97e
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SH3TC1 ENPP1 LRRK1 IL4I1

1.48e-04165724d8b0a9b6f704b98e8f0412c11739879a26c036e2
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FLT1 UNC45B KDR ST6GALNAC2

1.51e-0416672427af6c906cff1d40d134f0386db7708869691121
ToppCelldroplet-Thymus-nan-3m-Myeloid-B_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCSK IL4I1 SH2B2 ADCY9

1.51e-04166724c0af93db981dfd448abc7efcd257f3e5ff066aae
ToppCellCTRL-Myeloid-Monocyte|CTRL / Disease state, Lineage and Cell class

FLT1 TLR2 PFKFB3 F5

1.58e-0416872413dca90c7b811e4d5e8fa44f5e892e29be9787a6
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHPRH CSTF1 ADCY9 TRPT1

1.58e-04168724de1042267407719f19eb3f580a5df0c9cd0e8273
ToppCellCTRL-Myeloid-Monocyte|Myeloid / Disease state, Lineage and Cell class

FLT1 TLR2 PFKFB3 F5

1.69e-04171724bfa01571516a0b24476ae06cb07f56c5579dbd70
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLT1 UNC45B KDR PFKFB3

1.73e-04172724c84cab89c97d647b8a256fd08e33d9102810febd
ToppCellControl-MAIT|Control / Disease group and Cell class

ABCC3 FLT1 SPEF2 TTC34

1.73e-04172724552bc62e8e8bb0ac1cd0452f4410a3af087787eb
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

SH3TC1 ZFYVE26 IL4I1 SH2B2

1.77e-041737248384d533a1071fc65a06e6d9f5f17d8ab00c3966
ToppCelldroplet-Heart-4Chambers-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 SH3TC1 UNC45B KDR

1.77e-041737249a04271c51fae34f547db3206f9ff5857686e45c
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR SLC27A2

1.81e-04174724fa6eb451555766398996bbe8f555a3f4c0f3c108
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR SLC27A2

1.81e-041747241f5b0fa58b2a7335667357af7e50e5242cd13d7d
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR SLC27A2

1.81e-04174724ac3aee6ed49d1c421f33509e3ffc5cb17750a473
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLT1 UNC45B KDR ADGRG6

1.85e-041757242e54961846c65b185d9bd6e305dd81205579d890
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLT1 UNC45B KDR ADGRG6

1.85e-04175724efa6a05f7417d46141b6e635f258c126b7a03aa1
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLT1 UNC45B KDR ST6GALNAC2

1.85e-041757247be76d39e1a4f4ac709672cd2d409a2523a083ce
ToppCellT_cells-Tph_and_Tfh|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

FLT1 THADA F5 SLC27A2

1.89e-0417672456c055488e34605d32562571a2fee621b47c9441
ToppCellfacs-Aorta|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MYH8 UNC45B KDR

1.89e-041767240b3491451be02c18a16cdb875645be47eb867a7f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 LDHAL6A KDR ANKRD55

1.89e-0417672464e426f5e84884ce2c29acf6f4b958962a63927f
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Pitx2_(Subthalamic_nucleus_(STN))-|Thalamus / BrainAtlas - Mouse McCarroll V32

RHCG MYH8 EEF1AKMT3

1.91e-046972310d5fccc1fa10ffc9051df42dd0e5046d97ec4af
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Pitx2_(Subthalamic_nucleus_(STN))|Thalamus / BrainAtlas - Mouse McCarroll V32

RHCG MYH8 EEF1AKMT3

1.91e-04697239d7e911434c6b18327fa7adaec5c449e0c300919
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR PFKFB3

1.93e-04177724ca5a30b3e7bcfdd8de01ceaf7449735b5cd503af
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR PFKFB3

1.93e-04177724f471f7747d6e8db7546899019af9508f48a14f89
ToppCell368C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PIK3R4 ENPP1 OAS3 METAP1D

1.93e-04177724946803293a7955116c80f403e99e4093e798ca3f
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR PFKFB3

1.93e-04177724cd0684b876c2a7d5fe7e2773e8e25bb61ecbc795
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-cDC1|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRRK1 IL4I1 ITPRIPL1 NOD2

1.93e-04177724345cebc19f93970a9a46be139208b300081f5493
ToppCelldroplet-Bladder-BLADDER-1m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KANK4 KDR

1.98e-041787246bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCellASK440-Epithelial-Transformed_epithelium|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

FLT1 SHPRH PFKFB3 TARS2

1.98e-0417872486f1741636ed3e85bb4a65f84949b718fc38c290
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B ST6GALNAC2 ADGRG6

2.02e-04179724a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCelldroplet-Fat-Gat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR PRAG1

2.02e-0417972408cf9986804a6417a9afb19b50c69a3554f71ec6
ToppCellCV-Severe-4|Severe / Virus stimulation, Condition and Cluster

TTC34 F5 SLC27A2 TRPT1

2.06e-04180724cf84a01e6a33e5d27ad7be1d9069a0370b5116d1
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLT1 SH3TC1 KDR ITPRIPL1

2.06e-04180724455d1e3ccf2ab609954f3b870e8f514ddca735f4
ToppCell(01)_Cycling_Basal_(homeostasis)-(1)_24hpi|(01)_Cycling_Basal_(homeostasis) / shred by cell type and Timepoint

ADCY9 ADGRG6 NOD2

2.08e-04717236aa56b0daaeb5e0ae30619f9c6945c8e42899b27
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B APAF1 KDR

2.11e-041817244df7972f88117108698efd06b124b232f8588981
ToppCellControl-Myeloid-DC1|Control / Condition, Lineage and Cell class

ENPP1 LRRK1 ITPRIPL1 ADGRG6

2.11e-041817245a2a1f017ad23baed9972c68b4a46f4c618ef21a
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B APAF1 KDR

2.11e-04181724cbb530566893281289026bfd93adf721decd4ca3
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLT1 UNC45B KDR NOD2

2.15e-04182724840427d1c23d60482c943ff006b14007ed44d247
ToppCelldroplet-Kidney-nan-3m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KANK4 KDR

2.15e-04182724f4a5f1c3a04c0566eb96607dab7a0d9a5ebc3fd1
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 ENPP1 FGFR4 F5

2.20e-04183724d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT1 KDR IL4I1 SH2B2

2.24e-04184724c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 UNC45B KDR ITPRIPL1

2.29e-04185724c3105978d971da7d0fad1a717ee29afee5ed6357
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLT1 KDR IL4I1 SH2B2

2.29e-04185724808d5e880069aff8866cd2c733b9fe568a37701f
Diseasecerebral cavernous malformation (is_marker_for)

FLT1 KDR

1.52e-053672DOID:0060669 (is_marker_for)
Diseaseallergic contact dermatitis (is_marker_for)

FLT1 KDR

1.52e-053672DOID:3042 (is_marker_for)
Diseasearteriovenous malformations of the brain (is_marker_for)

FLT1 KDR

1.52e-053672DOID:0060688 (is_marker_for)
Diseasemeningococcal meningitis (is_implicated_in)

TLR2 NOD2

3.04e-054672DOID:0080176 (is_implicated_in)
Diseaselatent autoimmune diabetes in adults

THADA PFKFB3

3.04e-054672EFO_0009706
DiseaseHypophosphatemic rickets

CLCN5 ENPP1

5.06e-055672cv:C1704375
DiseaseHereditary hypophosphatemic rickets

CLCN5 ENPP1

5.06e-055672cv:CN296404
DiseaseRickets

CLCN5 ENPP1

5.06e-055672cv:C0035579
Diseaserheumatoid arthritis, ACPA-negative rheumatoid arthritis

TYK2 ANKRD55

5.06e-055672EFO_0000685, EFO_0009460
Diseasetorsin-1A-interacting protein 1 measurement

SARM1 F5

7.57e-056672EFO_0802137
Diseaseosteopetrosis (implicated_via_orthology)

CLCN5 LRRK1

1.06e-047672DOID:13533 (implicated_via_orthology)
DiseaseX-16935 measurement

ABCC3 SLC27A2

1.06e-047672EFO_0800763
Diseasecolitis (biomarker_via_orthology)

SI KDR NOD2

1.21e-0442673DOID:0060180 (biomarker_via_orthology)
Diseasenasopharynx carcinoma (is_marker_for)

FLT1 KDR FGFR4

1.29e-0443673DOID:9261 (is_marker_for)
Diseasepsoriasis (is_marker_for)

FLT1 TLR2 KDR

1.39e-0444673DOID:8893 (is_marker_for)
Diseaseleprosy (is_implicated_in)

TLR2 NOD2

1.41e-048672DOID:1024 (is_implicated_in)
DiseaseE3 ubiquitin-protein ligase RNF13 measurement

SARM1 F5

1.41e-048672EFO_0801556
DiseaseDistal arthrogryposis

MYH3 MYH8

1.81e-049672cv:C0265213
Diseaseinterferon alpha/beta receptor 1 measurement

TYK2 SARM1

1.81e-049672EFO_0021850
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH3 MYH8

2.26e-0410672DOID:0111269 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH3 MYH8

2.26e-0410672DOID:0111602 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH3 MYH8

2.26e-0410672DOID:0111596 (implicated_via_orthology)
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH3 MYH8

2.26e-0410672DOID:0110454 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH3 MYH8

2.26e-0410672DOID:0080719 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH3 MYH8

2.26e-0410672DOID:3429 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH3 MYH8

2.26e-0410672DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH3 MYH8

2.26e-0410672DOID:0080326 (implicated_via_orthology)
DiseaseAntithrombotic agent use measurement

FLT1 TNKS F5

2.70e-0455673EFO_0009925
Diseaseretinopathy of prematurity (biomarker_via_orthology)

FLT1 KDR

3.30e-0412672DOID:13025 (biomarker_via_orthology)
Diseasedistal myopathy (implicated_via_orthology)

MYH3 MYH8

3.30e-0412672DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MYH3 MYH8

3.30e-0412672DOID:2106 (implicated_via_orthology)
Diseasethyroid gland carcinoma (is_marker_for)

FLT1 KDR

3.30e-0412672DOID:3963 (is_marker_for)
Diseasemacular retinal edema (is_marker_for)

FLT1 KDR

3.30e-0412672DOID:4449 (is_marker_for)
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

DNHD1 FLT1 APAF1 KDR

3.64e-04148674C0279702
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH3 MYH8

3.90e-0413672DOID:397 (implicated_via_orthology)
DiseaseT-cell surface glycoprotein CD3 epsilon chain measurement

SARM1 F5

3.90e-0413672EFO_0802114
Diseaserheumatoid arthritis, ACPA-positive rheumatoid arthritis, rheumatoid factor seropositivity measurement

TYK2 TTC34 ANKRD55

4.03e-0463673EFO_0000685, EFO_0007791, EFO_0009459
DiseaseKuhnt-Junius degeneration (is_marker_for)

FLT1 TLR2

4.54e-0414672DOID:10873 (is_marker_for)
DiseaseCrohn's disease

TYK2 THADA KANK4 GSAP ANKRD55 NOD2

4.98e-04441676EFO_0000384
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH3 MYH8

5.23e-0415672DOID:0050646 (implicated_via_orthology)
Diseaseinflammatory bowel disease

TYK2 THADA DHDDS F5 ANKRD55 NOD2

5.47e-04449676EFO_0003767
DiseaseSpondyloepiphyseal Dysplasia

FLT1 KDR

5.97e-0416672C0038015
DiseaseSpondyloepiphyseal Dysplasia Tarda, X-Linked

FLT1 KDR

5.97e-0416672C3541456
DiseaseSchwartz-Jampel Syndrome, Type 1

FLT1 KDR

5.97e-0416672C4551479
DiseaseSchwartz-Jampel Syndrome

FLT1 KDR

5.97e-0416672C0036391
DiseaseMelnick-Needles Syndrome

FLT1 KDR

5.97e-0416672C0025237
Diseaseblood phosphate measurement

ENPP1 FGFR4 PRAG1 ADCY9

6.70e-04174674EFO_0010972
DiseaseRheumatoid Arthritis

TYK2 ABCC3 TLR2 ANKRD55

6.70e-04174674C0003873
Diseaseallergic rhinitis (is_marker_for)

TLR2 NOD2

6.76e-0417672DOID:4481 (is_marker_for)
DiseaseEye Abnormalities

APAF1 CRPPA

6.76e-0417672C0015393
DiseaseKuhnt-Junius degeneration (is_implicated_in)

FLT1 KDR

6.76e-0417672DOID:10873 (is_implicated_in)
DiseaseUremia

FLT1 KDR

6.76e-0417672C0041948
DiseaseVan Buchem disease

FLT1 KDR

6.76e-0417672C0432272
DiseaseHemangiosarcoma

FLT1 KDR

7.59e-0418672C0018923
DiseaseOsteochondrodysplasias

FLT1 KDR

8.47e-0419672C0029422
Diseasekidney failure (biomarker_via_orthology)

RHCG TLR2

8.47e-0419672DOID:1074 (biomarker_via_orthology)
DiseaseDyschondroplasias

FLT1 KDR

8.47e-0419672C0013366
Diseaseurinary microalbumin measurement

MON2 CRPPA

9.40e-0420672EFO_0010967
DiseaseMultiple Epiphyseal Dysplasia

FLT1 KDR

9.40e-0420672C0026760
DiseaseDeep Vein Thrombosis

KDR F5

1.04e-0321672C0149871
DiseaseVenous Thrombosis

KDR F5

1.04e-0321672C0042487
Diseasepre-eclampsia (is_implicated_in)

FLT1 F5

1.47e-0325672DOID:10591 (is_implicated_in)
DiseaseCerebral Hemorrhage

FLT1 KDR

1.85e-0328672C2937358
Diseaserespiratory failure, COVID-19

TYK2 OAS3

1.98e-0329672EFO_0009686, MONDO_0100096
Diseaserhinitis (is_implicated_in)

TLR2 NOD2

2.12e-0330672DOID:4483 (is_implicated_in)
Diseaseobesity

TNKS PFKFB3 PRAG1 ADCY9

2.22e-03241674EFO_0001073

Protein segments in the cluster

PeptideGeneStartEntry
LLLPLHELRGHNGCV

APAF1

1116

O14727
GLRLHTVNVRQLGHC

ADGRG6

511

Q86SQ4
LILCNQIHHGLRSGI

FBXO10

521

Q9UK96
LIGRHKNIINLLGVC

FGFR4

526

P22455
LLLGTLQHLCRPHGT

EEF1AKMT3

161

Q96AZ1
GNRILCSIILSHHQG

ANKRD55

206

Q3KP44
FHQQRLGHGLIISCP

FAM187A

276

A6NFU0
NGLHLHNLRGLLCAL

DNHD1

1921

Q96M86
GRVASLLEHHALQLC

CCDC22

201

O60826
LLEHHALQLCQQTGR

CCDC22

206

O60826
GHAGRHLQQIILDQC

CRPPA

321

A4D126
GGIQAARVLHQALLH

ABCC3

1036

O15438
GLHQACQLARHVLLL

METAP1D

96

Q6UB28
LHALQHPCIVALIGI

LRRK1

1311

Q38SD2
LGGHTACVRLLLQHR

ASB18

161

Q6ZVZ8
LVLHQLRCNGVLEGI

MYH8

691

P13535
LCRHGENEHNLQGRI

PFKFB3

251

Q16875
NLHRCLNLILISDHG

ENPP1

411

P22413
RTLLNLAHCHGAVLG

MON2

681

Q7Z3U7
SHQHRLGLGVRALNL

PORCN

386

Q9H237
LGRGLQQRSLHHFLI

ITPRIPL1

481

Q6GPH6
NLGLITLIGLNSHLH

OR8B12

41

Q8NGG6
VQLGPGSVLQHCHLQ

FCSK

376

Q8N0W3
LHTILGVQCLPLHNL

GSAP

701

A4D1B5
LQELHRHGLGNLLLS

C4orf50

96

Q6ZRC1
HGAQRLLCVALGQLD

HDAC10

501

Q969S8
LLQGLNLLRQHHELC

KLHL28

21

Q9NXS3
LGLRQCLVTHNGRLL

CLCN5

776

P51795
LLSRGLLHGCIHAIG

ADCY9

281

O60503
ACHHGNVDLVRLLLA

KANK4

936

Q5T7N3
LLLCNHHTLGDQIIT

CUL9

876

Q8IWT3
LLGNVLVCVLAHHFG

HBB

106

P68871
LLSLGHNNIVRCIVH

CSTF1

391

Q05048
LQKHGVCIRVLGDLH

DHDDS

111

Q86SQ9
GLRTVLGLIQQHQHL

OAS3

251

Q9Y6K5
HRILHKLCQGLGLNL

IL4I1

121

Q96RQ9
SGKLQVHLRGLHNLC

MTX1

366

Q13505
LVDLCQGPHLRHTGQ

TARS2

236

Q9BW92
FLLQHSIPGCHLLGR

UBOX5

331

O94941
PSNNCILGHILHRLA

SPEF2

526

Q9C093
IHQHCQVRIDTLGLL

THADA

631

Q6YHU6
RTLCLQHGPLITFHL

TNRC6C

1531

Q9HCJ0
VRLHLLNIGGSQDIH

F5

1826

P12259
HDHLGLRQGDCVALL

SLC27A2

96

O14975
QQHLLLPLGRLHALC

PRORY

116

Q9H606
GKGQACRHLLHLAIQ

ST6GALNAC2

61

Q9UJ37
RQLVCALNGLAGIHI

SHPRH

1021

Q149N8
CGRDFTHVLLQLGHL

SH3TC1

941

Q8TE82
THVLLQLGHLCTRQG

SH3TC1

946

Q8TE82
EHSLVLHQLRCNGVL

MYH3

686

P11055
INLHVRGGHILPCQE

SI

1681

P14410
LLKGLSCQGRTHIHL

TRPT1

141

Q86TN4
IRKDLGNIIHNLCGH

PIK3R4

346

Q99570
LCLHDQLSVQHRGLV

UNC45B

856

Q8IWX7
RLLQETSALHGLCHL

NOD2

471

Q9HC29
LLCSGHLLVQLRHLG

ROM1

36

Q03395
QQLLEDCGIHLGVHR

SARM1

521

Q6SZW1
HRAALAGHLQTCRLL

TNKS

596

O95271
SLLHLSRLCVRHNLG

SPSB2

226

Q99619
HLRLSLNGHGQCHVQ

SH2B2

466

O14492
GLRNIHIFGLANVLH

VCPIP1

286

Q96JH7
LLQLCNGLEHLKEHG

PRAG1

1126

Q86YV5
FHIINIGRLCLDQHS

MTHFD2L

171

Q9H903
RLHIQDTCGINNLHG

RHCG

331

Q9UBD6
LKCGLIQHQLIHSGA

ZNF416

421

Q9BWM5
ARGLLLIQHQRIHTG

ZNF420

541

Q8TAQ5
HIGHHLNVVNLLGAC

KDR

891

P35968
GHHLNVVNLLGACTK

FLT1

886

P17948
LIHLCLLHLRASGQP

VSIG10L2

16

P0DP72
LILLTGVLCHRFHGL

TLR2

601

O60603
RQLLQGHCHARALAI

TTC34

131

A8MYJ7
LNLHRDSIACGHQLI

ZFYVE26

1941

Q68DK2
VHGNVCGRNILLARL

TYK2

731

P29597
QRLGIHSESCHGLIL

LDHAL6A

176

Q6ZMR3