Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE1 SYNE2

6.88e-055532GO:0140444
GeneOntologyBiologicalProcesspositive regulation of mRNA splicing, via spliceosome

RBMXL2 RBMXL3 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

1.81e-1344538GO:0048026
GeneOntologyBiologicalProcesspositive regulation of mRNA processing

RBMXL2 RBMXL3 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

4.55e-1349538GO:0050685
GeneOntologyBiologicalProcesspositive regulation of RNA splicing

RBMXL2 RBMXL3 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

3.80e-1263538GO:0033120
GeneOntologyBiologicalProcessregulation of mRNA splicing, via spliceosome

RBMXL2 RBMXL3 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

1.32e-09129538GO:0048024
GeneOntologyBiologicalProcessregulation of mRNA processing

RBMXL2 RBMXL3 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

6.56e-09158538GO:0050684
GeneOntologyBiologicalProcessregulation of RNA splicing

RBMXL2 RBMXL3 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

5.41e-08207538GO:0043484
GeneOntologyBiologicalProcessmRNA splicing, via spliceosome

RBMXL2 RBMXL3 CDC40 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

2.92e-07358539GO:0000398
GeneOntologyBiologicalProcessRNA splicing, via transesterification reactions with bulged adenosine as nucleophile

RBMXL2 RBMXL3 CDC40 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

2.92e-07358539GO:0000377
GeneOntologyBiologicalProcesspositive regulation of mRNA metabolic process

RBMXL2 RBMXL3 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

3.02e-07259538GO:1903313
GeneOntologyBiologicalProcessRNA splicing, via transesterification reactions

RBMXL2 RBMXL3 CDC40 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

3.21e-07362539GO:0000375
GeneOntologyBiologicalProcessRNA splicing

RBMXL2 RBMXL3 CDC40 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

4.77e-06502539GO:0008380
GeneOntologyBiologicalProcessmRNA processing

RBMXL2 RBMXL3 CDC40 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

1.01e-05551539GO:0006397
GeneOntologyBiologicalProcessregulation of mRNA metabolic process

RBMXL2 RBMXL3 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

1.62e-05443538GO:1903311
GeneOntologyBiologicalProcessmicrotubule-based movement

KIF13B DNAH3 SYNE2 FMN2 ULK4 CFAP69 IQUB

2.54e-04493537GO:0007018
GeneOntologyBiologicalProcessactin filament-based process

CYRIA MYH11 XIRP2 ELMO2 PECAM1 SYNE2 FMN2 CTNNA2 ACAP2

4.77e-04912539GO:0030029
GeneOntologyBiologicalProcessmRNA metabolic process

RBMXL2 RBMXL3 CDC40 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

4.97e-04917539GO:0016071
GeneOntologyCellularComponentspliceosomal complex

RBMXL2 RBMXL3 CDC40 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

3.26e-09215539GO:0005681
GeneOntologyCellularComponentnuclear protein-containing complex

KMT2C RBMXL2 RBMXL3 CDC40 SYNE1 CECR2 RBMY1A1 RBMY1C SYNE2 RBMY1F RBMY1D RBMY1B RBMY1E

2.92e-0513775313GO:0140513
GeneOntologyCellularComponentsmooth muscle contractile fiber

MYH11 PECAM1

6.28e-055532GO:0030485
GeneOntologyCellularComponentmale germ cell nucleus

RBMY1A1 RBMY1D RBMY1B RBMY1E

6.70e-0586534GO:0001673
GeneOntologyCellularComponentgerm cell nucleus

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.93e-04113534GO:0043073
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE1 SYNE2

3.42e-0411532GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE1 SYNE2

3.42e-0411532GO:0034993
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE1 SYNE2

3.42e-0411532GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE1 SYNE2

3.42e-0411532GO:0106094
GeneOntologyCellularComponentcontractile muscle fiber

MYH11 XIRP2 SYNE1 PECAM1 SYNE2

8.27e-04290535GO:0043292
GeneOntologyCellularComponentplatelet alpha granule membrane

PECAM1 PCDH7

8.37e-0417532GO:0031092
GeneOntologyCellularComponentaxoneme

DNAH3 CFAP69 IQUB BRWD1

1.87e-03207534GO:0005930
GeneOntologyCellularComponentciliary plasm

DNAH3 CFAP69 IQUB BRWD1

1.90e-03208534GO:0097014
GeneOntologyCellularComponentcytoplasmic region

DNAH3 CTNNA2 CFAP69 IQUB BRWD1

2.15e-03360535GO:0099568
GeneOntologyCellularComponentU12-type spliceosomal complex

RBMXL2 RBMXL3

2.62e-0330532GO:0005689
GeneOntologyCellularComponentsupramolecular fiber

KIF13B DNAH3 MYH11 XIRP2 SYNE1 PECAM1 SYNE2 FMN2 FSD1

2.63e-031179539GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

KIF13B DNAH3 MYH11 XIRP2 SYNE1 PECAM1 SYNE2 FMN2 FSD1

2.75e-031187539GO:0099081
GeneOntologyCellularComponentribonucleoprotein complex

RBMXL2 RBMXL3 CDC40 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

2.86e-031194539GO:1990904
GeneOntologyCellularComponentnuclear outer membrane

SYNE1 SYNE2

4.63e-0340532GO:0005640
DomainRBM1CTR

RBMXL2 RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

8.53e-158516PF08081
DomainRBM1CTR

RBMXL2 RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

8.53e-158516IPR012604
DomainRRM_1

RBMXL2 RBMXL3 RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

1.47e-06208517PF00076
DomainRRM

RBMXL2 RBMXL3 RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

1.95e-06217517SM00360
DomainRRM_dom

RBMXL2 RBMXL3 RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

2.62e-06227517IPR000504
DomainRRM

RBMXL2 RBMXL3 RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

2.86e-06230517PS50102
DomainNucleotide-bd_a/b_plait

RBMXL2 RBMXL3 RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

6.10e-06258517IPR012677
DomainKASH

SYNE1 SYNE2

4.37e-054512PF10541
DomainKASH

SYNE1 SYNE2

4.37e-054512IPR012315
DomainKASH

SYNE1 SYNE2

4.37e-054512PS51049
DomainKASH

SYNE1 SYNE2

4.37e-054512SM01249
Domain-

RBMXL2 RBMXL3 RBMY1F RBMY1D RBMY1B RBMY1E

5.15e-052445163.30.70.330
Domain-

ELMO2 ULK4 PSMD2 CFAP69 TRIP12

3.41e-042225151.25.10.10
DomainARM-like

ELMO2 ULK4 PSMD2 CFAP69 TRIP12

8.30e-04270515IPR011989
DomainAT_hook

KMT2C CECR2

8.56e-0416512PF02178
DomainActinin_actin-bd_CS

SYNE1 SYNE2

1.78e-0323512IPR001589
DomainSpectrin

SYNE1 SYNE2

1.78e-0323512PF00435
DomainACTININ_2

SYNE1 SYNE2

1.78e-0323512PS00020
DomainACTININ_1

SYNE1 SYNE2

1.78e-0323512PS00019
DomainARM-type_fold

ELMO2 ULK4 PSMD2 CFAP69 TRIP12

2.27e-03339515IPR016024
DomainBromodomain_CS

CECR2 BRWD1

2.28e-0326512IPR018359
DomainAnk_2

KIDINS220 ANKRD30B ACAP2 NOTCH2

2.79e-03215514PF12796
DomainSpectrin_repeat

SYNE1 SYNE2

2.83e-0329512IPR002017
DomainHMGI/Y_DNA-bd_CS

KMT2C CECR2

3.23e-0331512IPR000637
DomainSpectrin/alpha-actinin

SYNE1 SYNE2

3.44e-0332512IPR018159
DomainSPEC

SYNE1 SYNE2

3.44e-0332512SM00150
DomainAnk

KIDINS220 ANKRD30B ACAP2 NOTCH2

3.45e-03228514PF00023
DomainBROMODOMAIN_1

CECR2 BRWD1

4.58e-0337512PS00633
Domain-

KIDINS220 ANKRD30B ACAP2 NOTCH2

4.65e-032485141.25.40.20
DomainBromodomain

CECR2 BRWD1

4.83e-0338512PF00439
DomainANK

KIDINS220 ANKRD30B ACAP2 NOTCH2

4.85e-03251514SM00248
DomainANK_REPEAT

KIDINS220 ANKRD30B ACAP2 NOTCH2

4.99e-03253514PS50088
DomainAnkyrin_rpt-contain_dom

KIDINS220 ANKRD30B ACAP2 NOTCH2

5.06e-03254514IPR020683
DomainANK_REP_REGION

KIDINS220 ANKRD30B ACAP2 NOTCH2

5.06e-03254514PS50297
DomainBROMODOMAIN_2

CECR2 BRWD1

5.60e-0341512PS50014
DomainAnkyrin_rpt

KIDINS220 ANKRD30B ACAP2 NOTCH2

5.64e-03262514IPR002110
DomainBROMO

CECR2 BRWD1

5.87e-0342512SM00297
DomainBromodomain

CECR2 BRWD1

5.87e-0342512IPR001487
Domain-

CECR2 BRWD1

5.87e-03425121.20.920.10
PathwayWP_MRNA_PROCESSING

RBMXL2 RBMXL3 CDC40 RBMY1A1 RBMY1D RBMY1B RBMY1E BRWD1

2.17e-05451388MM15946
Pubmed

A Y chromosome gene family with RNA-binding protein homology: candidates for the azoospermia factor AZF controlling human spermatogenesis.

RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

6.53e-1775368269511
Pubmed

Structure and organization of the RBMY genes on the human Y chromosome: transposition and amplification of an ancestral autosomal hnRNPG gene.

RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

8.57e-15125369598316
Pubmed

RBMY, a male germ cell-specific RNA-binding protein, activated in human liver cancers and transforms rodent fibroblasts.

RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

4.06e-14653515184870
Pubmed

Degeneracy in human multicopy RBM (YRRM), a candidate spermatogenesis gene.

RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

1.42e-1375358875892
Pubmed

RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing.

RBMXL2 RBMY1A1 RBMY1C RBMY1F RBMY1B

8.63e-121353510749975
Pubmed

An RBM homologue maps to the mouse Y chromosome and is expressed in germ cells.

RBMY1A1 RBMY1D RBMY1B RBMY1E

2.40e-1155348817321
Pubmed

Human RBMY regulates germline-specific splicing events by modulating the function of the serine/arginine-rich proteins 9G8 and Tra2-{beta}.

RBMY1A1 RBMY1D RBMY1B RBMY1E

2.40e-11553420016065
Pubmed

The role of human and mouse Y chromosome genes in male infertility.

RBMY1A1 RBMY1D RBMY1B RBMY1E

2.40e-11553411097427
Pubmed

Rapid evolution of mouse Y centromere repeat DNA belies recent sequence stability.

RBMY1A1 RBMY1D RBMY1B RBMY1E

2.40e-11553419737860
Pubmed

The behavior of the X- and Y-chromosomes in the oocyte during meiotic prophase in the B6.Y(TIR)sex-reversed mouse ovary.

RBMY1A1 RBMY1D RBMY1B RBMY1E

7.19e-11653418239052
Pubmed

Identification of target messenger RNA substrates for mouse RBMY.

RBMY1A1 RBMY1D RBMY1B RBMY1E

7.19e-11653418492746
Pubmed

Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist.

RBMY1A1 RBMY1D RBMY1B RBMY1E

7.19e-11653412356914
Pubmed

Mouse homologues of the human AZF candidate gene RBM are expressed in spermatogonia and spermatids, and map to a Y chromosome deletion interval associated with a high incidence of sperm abnormalities.

RBMY1A1 RBMY1D RBMY1B RBMY1E

7.19e-1165349499427
Pubmed

Does Rbmy have a role in sperm development in mice?

RBMY1A1 RBMY1D RBMY1B RBMY1E

7.19e-11653415051956
Pubmed

RNA-binding motif protein 15 binds to the RNA transport element RTE and provides a direct link to the NXF1 export pathway.

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.68e-10753417001072
Pubmed

The roles of RNA-binding proteins in spermatogenesis and male infertility.

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.68e-10753410377282
Pubmed

Y chromosome short arm-Sxr recombination in XSxr/Y males causes deletion of Rbm and XY female sex reversal.

RBMY1A1 RBMY1D RBMY1B RBMY1E

3.35e-1085347479793
Pubmed

Mice with Y chromosome deletion and reduced Rbm genes on a heterozygous Dazl1 null background mimic a human azoospermic factor phenotype.

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.00e-091053410601091
Pubmed

Characterisation of the coding sequence and fine mapping of the human DFFRY gene and comparative expression analysis and mapping to the Sxrb interval of the mouse Y chromosome of the Dffry gene.

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.00e-09105349384609
Pubmed

The role of Dby mRNA in early development of male mouse zygotes.

RBMY1A1 RBMY1D RBMY1B RBMY1E

2.36e-091253420543856
Pubmed

GASZ promotes germ cell derivation from embryonic stem cells.

RBMY1A1 RBMY1D RBMY1B RBMY1E

3.40e-091353423816659
Pubmed

Absence of mDazl produces a final block on germ cell development at meiosis.

RBMY1A1 RBMY1D RBMY1B RBMY1E

4.76e-091453414611631
Pubmed

Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.

RBMY1A1 RBMY1D RBMY1B RBMY1E

6.48e-091553414762062
Pubmed

Loss of maternal Trim28 causes male-predominant early embryonic lethality.

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.13e-081753428115466
Pubmed

Sex differences in sex chromosome gene expression in mouse brain.

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.45e-081853412023983
Pubmed

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.

RBMXL2 RBMXL3 CDC40 RBMY1A1 RBMY1D RBMY1B RBMY1E BRWD1

5.43e-0834753816033648
Pubmed

MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice.

RBMY1A1 RBMY1D RBMY1B RBMY1E

7.01e-082653435920200
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

KIF13B JCAD RAPGEF6 ELMO2 SYNE2 FMN2 FSD1 TRIP12 PCDH7 NOTCH2

6.11e-07861531036931259
Pubmed

Lineage-specific biology revealed by a finished genome assembly of the mouse.

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.55e-065553419468303
Pubmed

An abundance of X-linked genes expressed in spermatogonia.

RBMY1A1 RBMY1D RBMY1B RBMY1E

2.06e-065953411279525
Pubmed

Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.

SYNE1 SYNE2

2.28e-06253222768332
Pubmed

Potential dual functional roles of the Y-linked RBMY in hepatocarcinogenesis.

RBMY1A1 RBMY1B

2.28e-06253232473614
Pubmed

Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.

SYNE1 SYNE2

2.28e-06253211792814
Pubmed

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.

SYNE1 SYNE2

2.28e-06253224931616
Pubmed

Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.

SYNE1 SYNE2

2.28e-06253217267447
Pubmed

Nesprins: tissue-specific expression of epsilon and other short isoforms.

SYNE1 SYNE2

2.28e-06253224718612
Pubmed

Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.

SYNE1 SYNE2

2.28e-06253224586179
Pubmed

Haploinsufficiency of the germ cell-specific nuclear RNA binding protein hnRNP G-T prevents functional spermatogenesis in the mouse.

RBMXL2 RBMXL3

2.28e-06253218562473
Pubmed

An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning.

RBMXL2 RBMXL3

2.28e-06253230674417
Pubmed

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.

SYNE1 SYNE2

2.28e-06253217761684
Pubmed

Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.

SYNE1 SYNE2

2.28e-06253231578382
Pubmed

Generation of Pecam1 endothelial specific dual reporter mouse model.

MYH11 PECAM1

2.28e-06253232618127
Pubmed

RAD21 cooperates with pluripotency transcription factors in the maintenance of embryonic stem cell identity.

RBMXL2 RBMXL3 NACC1 PSMD2 TRIP12

2.97e-0614653521589869
Pubmed

Essential role for thymosin β4 in regulating vascular smooth muscle cell development and vessel wall stability.

MYH11 ANPEP PECAM1

3.18e-061953322723298
Pubmed

Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis.

MYH11 PECAM1 NOTCH2

5.79e-062353319897741
Pubmed

Targeted disruption of the histone lysine 79 methyltransferase Dot1L in nephron progenitors causes congenital renal dysplasia.

MYH11 PECAM1 NOTCH2

5.79e-062353333315499
Pubmed

The germ cell nuclear proteins hnRNP G-T and RBMY activate a testis-specific exon.

RBMXL2 RBMY1A1

6.83e-06353219893608
Pubmed

Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.

SYNE1 SYNE2

6.83e-06353210878022
Pubmed

Aminopeptidase N/CD13 induces angiogenesis through interaction with a pro-angiogenic protein, galectin-3.

ANPEP PECAM1

6.83e-06353217888402
Pubmed

The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.

SYNE1 SYNE2

6.83e-06353216079285
Pubmed

The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.

SYNE1 SYNE2

6.83e-06353212408964
Pubmed

Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.

SYNE1 SYNE2

6.83e-06353217462627
Pubmed

Impaired angiogenesis in aminopeptidase N-null mice.

ANPEP PECAM1

6.83e-06353217360568
Pubmed

Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.

SYNE1 SYNE2

6.83e-06353233472039
Pubmed

Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.

SYNE1 SYNE2

6.83e-06353225516977
Pubmed

Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.

MYH11 PECAM1 NOTCH2

1.19e-052953325535917
Pubmed

SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.

SYNE1 SYNE2

1.36e-05453216648470
Pubmed

LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.

SYNE1 SYNE2

1.36e-05453223071752
Pubmed

Expression of the Nkx3.1 homobox gene during pre and postnatal development.

MYH11 PECAM1

1.36e-05453210415359
Pubmed

Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.

SYNE1 SYNE2

1.36e-05453220108321
Pubmed

Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton.

SYNE1 SYNE2

1.36e-05453219596800
Pubmed

Notch2 is required for formation of the placental circulatory system, but not for cell-type specification in the developing mouse placenta.

PECAM1 NOTCH2

1.36e-05453217359302
Pubmed

Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.

SYNE1 SYNE2

1.36e-05453228716842
Pubmed

Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.38e-059553424029230
Pubmed

Lem2 is essential for cardiac development by maintaining nuclear integrity.

SYNE1 PECAM1 SYNE2

1.61e-053253337067297
Pubmed

Hepatocyte nuclear factor 4alpha is essential for embryonic development of the mouse colon.

MYH11 PECAM1 ATP12A

1.77e-053353316618389
Pubmed

A SOX17-PDGFB signaling axis regulates aortic root development.

MYH11 PECAM1 SEMA3G

1.93e-053453335831318
Pubmed

Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.

SYNE1 SYNE2

2.27e-05553218396275
Pubmed

LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.

SYNE1 SYNE2

2.27e-05553222632968
Pubmed

Notch2 is required for the proliferation of cardiac neural crest-derived smooth muscle cells.

PECAM1 NOTCH2

2.27e-05553218330927
Pubmed

The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes.

RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

3.35e-0524153512815422
Pubmed

Regulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase Rumi.

PECAM1 NOTCH2

3.40e-05653221490058
Pubmed

Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.

SYNE1 SYNE2

3.40e-05653233058875
Pubmed

TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton.

SYNE1 SYNE2

3.40e-05653218827015
Pubmed

The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility.

PECAM1 CTNNA2

3.40e-05653212975353
Pubmed

Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis.

MLKL PECAM1

3.40e-05653231748744
Pubmed

Loss of Notch2 and Notch3 in vascular smooth muscle causes patent ductus arteriosus.

MYH11 NOTCH2

4.76e-05753226453897
Pubmed

The asymmetric Pitx2 gene regulates gut muscular-lacteal development and protects against fatty liver disease.

MYH11 PECAM1

4.76e-05753234818545
Pubmed

Mfsd2a is critical for the formation and function of the blood-brain barrier.

ANPEP PECAM1

4.76e-05753224828040
Pubmed

Capturing novel mouse genes encoding chromosomal and other nuclear proteins.

CECR2 TRIP12

4.76e-0575329701556
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

JCAD RAPGEF6 CDC40 XIRP2 FSD1 TRIP12

4.85e-0543053635044719
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KIF13B MYH11 RBMXL2 SYNE1 SYNE2 ANKRD30B PSMD2 ATP12A CFAP69 TRIP12

5.57e-051442531035575683
Pubmed

Nkx2-5 suppresses the proliferation of atrial myocytes and conduction system.

PECAM1 NOTCH2

6.34e-05853224563458
Pubmed

Testosterone levels influence mouse fetal Leydig cell progenitors through notch signaling.

PECAM1 NOTCH2

6.34e-05853223467742
Pubmed

Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.

PECAM1 NOTCH2

6.34e-05853222156581
Pubmed

G9a controls placental vascular maturation by activating the Notch Pathway.

PECAM1 NOTCH2

6.34e-05853228455378
Pubmed

The identification of different endothelial cell populations within the mouse proepicardium.

MYH11 PECAM1

6.34e-05853221932312
Pubmed

A novel podocyte gene, semaphorin 3G, protects glomerular podocyte from lipopolysaccharide-induced inflammation.

PECAM1 SEMA3G

6.34e-05853227180624
Pubmed

Notch1 and Jagged1 expression by the developing pulmonary vasculature.

PECAM1 NOTCH2

6.34e-05853212242716
Pubmed

Numb regulates somatic cell lineage commitment during early gonadogenesis in mice.

PECAM1 NOTCH2

6.34e-05853228360133
Pubmed

Tbx18 is essential for normal development of vasculature network and glomerular mesangium in the mammalian kidney.

MYH11 PECAM1

8.15e-05953224727670
Pubmed

Tissue interactions pattern the mesenchyme of the embryonic mouse lung.

MYH11 PECAM1

8.15e-05953212781691
Pubmed

Nuclear membrane proteins with potential disease links found by subtractive proteomics.

SYNE1 SYNE2

1.02e-041053212958361
Pubmed

Patent ductus arteriosus in mice with smooth muscle-specific Jag1 deletion.

MYH11 PECAM1

1.02e-041053221068062
Pubmed

Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle.

SYNE1 SYNE2

1.02e-041053228533284
Pubmed

Evidence for developmental vascular-associated necroptosis and its contribution to venous-lymphatic endothelial differentiation.

MLKL PECAM1

1.02e-041053237576598
Pubmed

T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis.

RBMY1A1 RBMY1C

1.02e-041053210332027
Pubmed

A Non-canonical PDK1-RSK Signal Diminishes Pro-caspase-8-Mediated Necroptosis Blockade.

MLKL PECAM1

1.02e-041053232979304
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

KIDINS220 VPS13C SYNE2 FMN2 PCDH7 NOTCH2

1.16e-0450453634432599
Pubmed

Class 3 semaphorins negatively regulate dermal lymphatic network formation.

PECAM1 SEMA3G

1.24e-041153226319580
CytobandYq11.223

RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

8.13e-0893535Yq11.223
CytobandEnsembl 112 genes in cytogenetic band chrYq11

RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E

3.04e-05311535chrYq11
Cytoband16q23.1

MLKL CNTNAP4

6.34e-043253216q23.1
GeneFamilyRNA binding motif containing

RBMXL2 RBMXL3 RBMY1A1 RBMY1C RBMY1F RBMY1D RBMY1B RBMY1E

7.42e-09213368725
GeneFamilySpectrin repeat containing nuclear envelope family

SYNE1 SYNE2

2.31e-0543621252
GeneFamilyAnkyrin repeat domain containing

KIDINS220 ANKRD30B ACAP2 NOTCH2

1.32e-03242364403
CoexpressionCHEN_ETV5_TARGETS_TESTIS

RBMY1A1 RBMY1D RBMY1B RBMY1E

5.40e-0733524MM701
CoexpressionZHENG_IL22_SIGNALING_DN

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.93e-0645524MM763
CoexpressionACEVEDO_METHYLATED_IN_LIVER_CANCER_DN

KMT2C KIDINS220 VPS13C RBMY1A1 RBMY1F RBMY1D RBMY1B RBMY1E CNTNAP4 DGKG

7.10e-068735210M16009
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 SYNE1 SYNE2 ULK4 CFAP69 IQUB

8.84e-0819750674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MLKL GPR4 MYH11 PECAM1 PCDH7

1.78e-06180505455d1e3ccf2ab609954f3b870e8f514ddca735f4
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MLKL GPR4 SALL3 PECAM1 SEMA3G

2.50e-061935051e6e2d786511cc40241197368f5df20c20b882f3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 SYNE1 ULK4 CFAP69 IQUB

2.56e-061945054a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD GPR4 PECAM1 SYNE2 SEMA3G

2.76e-06197505e8e879b7634a29569061d3515d180784094a31e7
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

JCAD GPR4 PECAM1 SYNE2 SEMA3G

2.83e-0619850556b746e5791b47fe33a7872f0942ae0747b13d4a
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Endothelial|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

JCAD GPR4 PECAM1 SYNE2 SEMA3G

2.83e-06198505531b0f88c95f813e3914c96749f591e80ca321d0
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MLKL JCAD GPR4 PECAM1 SYNE2

2.97e-062005053585484c7e24e941708bee471ca607d8ccee74e6
ToppCellCOVID-19-kidney-Mito-rich_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

JCAD SYNE1 PECAM1 SYNE2

2.12e-05145504afed661aef990edb8e7012ab67ace56443520c9f
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MLKL GPR4 PECAM1 SEMA3G

2.36e-05149504d9c47f523c75ddcd6131e45d2ffc24b970932cae
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH11 CECR2 CNTNAP4 CTNNA2

3.12e-05160504c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH11 CECR2 CNTNAP4 CTNNA2

3.12e-0516050425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ULK4 FSD1 CTNNA2 IQUB

3.69e-05167504cf6206c506715cd846799c62cf7c06e3fa99f7af
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 ULK4 CFAP69 IQUB

3.87e-05169504fba841664939c771881ba97f14ef1df6635c04ff
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ULK4 FSD1 CTNNA2 IQUB

3.87e-0516950430141f76e9bfc2b4586429857c72dbc85ba65cc9
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DNAH3 MYH11 FMN2 DGKG

4.05e-05171504fe0665c5ca01b0b2cc8f20d64587f0847c3d215c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD SYNE1 PECAM1 DGKG

4.14e-05172504c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 SALL3 PECAM1 CTNNA2

4.43e-05175504c36b4526970db9ccfbe2c70b00961fab9f13b133
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 SALL3 PECAM1 CTNNA2

4.43e-05175504c1e082538f31b5c98ac63f71dcca4a1211a14708
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 SALL3 PECAM1 CTNNA2

4.43e-051755042f9b5bdf8a62e8e99d1c4f677a8e5525bfd3b4ce
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF13B XIRP2 VPS13C PCDH7

4.53e-05176504749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD GPR4 PECAM1 SEMA3G

4.73e-05178504360d7a987f91d6d721487a921824057ec31a7332
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF13B VPS13C SYNE1 SYNE2

4.73e-0517850401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)|367C / Donor, Lineage, Cell class and subclass (all cells)

JCAD GPR4 PECAM1 SEMA3G

4.73e-05178504e1e96a0e3ff718ebf676a982bc63e8ced6984059
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)-|367C / Donor, Lineage, Cell class and subclass (all cells)

JCAD GPR4 PECAM1 SEMA3G

4.73e-05178504363e8b23b3834692a8a79e5fdc7b43bd3a4dab5e
ToppCellhuman_hepatoblastoma-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MYH11 XIRP2 DGKG CTNNA2

4.84e-0517950414fc8ccb6b215063d747643f47d780d2b237eb67
ToppCellBronchial_Biopsy-Mesenchymal-Smooth_muscle|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

GPR4 MYH11 DGKG SEMA3G

4.94e-051805047085a851807e6a833965e1366946db0bbc5174e2
ToppCelldroplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD CECR2 PECAM1 SYNE2

5.05e-0518150492d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

JCAD SYNE1 PECAM1 SYNE2

5.05e-05181504c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCelldroplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD CECR2 PECAM1 SYNE2

5.16e-0518250481279877b920b5a1bc991a07d3031d6458700fe3
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH3 FMN2 CFAP69 IQUB

5.38e-051845045daff849625f2f41d56615569c0ed59cd733b34c
ToppCellEndothelial-A-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

JCAD GPR4 PECAM1 SEMA3G

5.50e-05185504dee0b7ba2f338f0979d2306aedf52ac35a36b60c
ToppCell356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|356C / Donor, Lineage, Cell class and subclass (all cells)

JCAD GPR4 PECAM1 SEMA3G

5.61e-05186504f0b78c7ee20279970ea8961bf59acb5262f2dce5
ToppCell356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|356C / Donor, Lineage, Cell class and subclass (all cells)

JCAD GPR4 PECAM1 SEMA3G

5.61e-051865042b3c814a7dee8286ea113c63dc3de5daf0257d37
ToppCellfacs-Heart-LA-24m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ZBTB39 PECAM1 PCDH7

5.73e-05187504d9943e65eedab73d141eae524e2411653a751705
ToppCellfacs-Heart-LA-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ZBTB39 PECAM1 PCDH7

5.73e-051875047b13c3b67d66f3afb410141d5471c9e78a4d8623
ToppCellEndothelial-A-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

JCAD GPR4 PECAM1 SEMA3G

5.73e-05187504fd93f3f4b82dae3bf4eef245bfedc2a9e3251b61
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MLKL JCAD GPR4 PECAM1

5.73e-05187504dffa8447c2f3fdacf39a7258c6b4e81a25245041
ToppCellfacs-Pancreas-Endocrine-3m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD GPR4 MYH11 PECAM1

5.85e-05188504da862ea3c74f42d0dbae38b09211a45c593d477e
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH3 FMN2 CFAP69 IQUB

5.85e-051885042b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCellfacs-Pancreas-Endocrine-3m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD GPR4 MYH11 PECAM1

5.85e-05188504b82a7667ef74a05e8bc744f6c090a7cc7b8efe32
ToppCellfacs-Pancreas-Endocrine-3m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD GPR4 MYH11 PECAM1

5.85e-0518850419672d284fe89c9c3c7697514ca1f659329c34f4
ToppCelldroplet-Pancreas-Endocrine-21m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD GPR4 MYH11 PECAM1

5.97e-0518950437ce47abd6f96df04d35a4a6189d007bef5ccc94
ToppCelldroplet-Pancreas-Endocrine-21m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD GPR4 MYH11 PECAM1

5.97e-05189504b55324cb365a827d071952709bbf0e8ef8c313de
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH3 FMN2 CFAP69 IQUB

5.97e-0518950468a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCelldroplet-Pancreas-Endocrine-21m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD GPR4 MYH11 PECAM1

5.97e-0518950462e46d59d3b89d4566b595c704d8b02f1ea9060b
ToppCellEndothelial-A-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

JCAD GPR4 PECAM1 SEMA3G

6.10e-051905046e83fa0eb8cabe0ffb35375f16e6bf3755ec4977
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JCAD GPR4 PECAM1 SEMA3G

6.10e-0519050406bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCellPCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MLKL JCAD PECAM1 SEMA3G

6.10e-051905049a2244c3973aee7270646bf00db7727edb9decc5
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD GPR4 PECAM1 SEMA3G

6.10e-05190504141266bf411ea675fbf889b20c1b08673c45ff95
ToppCellControl-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

JCAD SYNE1 PECAM1 SEMA3G

6.22e-05191504c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD PECAM1 SYNE2 SEMA3G

6.22e-05191504adb2e3efcad02889d8229325080da5e7830fd3ae
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYH11 SYNE1 DGKG PCDH7

6.22e-0519150408042952431ca1a6fd7dfc13f36eb28643979598
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYH11 SYNE1 DGKG PCDH7

6.22e-051915047853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellIPF-Epithelial-Goblet|Epithelial / Disease state, Lineage and Cell class

KIF13B ANPEP PECAM1 ATP12A

6.22e-05191504267e1192aaec468c1a59eb24848b37e0e18cbc44
ToppCellfacs-Heart-LA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ZBTB39 PECAM1 PCDH7

6.35e-0519250414a816ef116aa992f86edab411f043cf7d07fe04
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-Early_cap|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

JCAD GPR4 PECAM1 SEMA3G

6.35e-051925044986ef70a665fdfa1df86f7f8a15117487eae159
ToppCellfacs-Heart-LA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ZBTB39 PECAM1 PCDH7

6.35e-05192504847822514d747a21d5eb40e04ba9a023fd32bd65
ToppCell367C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

JCAD GPR4 PECAM1 SEMA3G

6.48e-051935045c6b03d6d98aa873fda1a201d44a912246bb5a92
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_capillary_(2)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MLKL JCAD PECAM1 SEMA3G

6.48e-051935044f38aae346ea3b4258744e9dc1e5aeb4fea13d06
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 CFAP69 PCDH7 IQUB

6.48e-05193504ea345d34440b25f65358a53dc72831998d1c3620
ToppCelldroplet-Bladder-nan-3m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 MYH11 PECAM1 SEMA3G

6.48e-051935048be24713f8ba2545b7647d1994e9e993623ddaa3
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH3 SYNE1 ULK4 CFAP69

6.48e-05193504ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCelldroplet-Bladder-nan-3m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 MYH11 PECAM1 SEMA3G

6.48e-0519350419dfc4a2c91fcea4f5991e7c44df46faeecb06b8
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ZBTB39 PECAM1 PCDH7

6.48e-051935042483bb7f398e4fa0ef09c8bd584ed25703853f03
ToppCelldroplet-Bladder-nan-3m-Endothelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 MYH11 PECAM1 SEMA3G

6.48e-05193504351e0acd411a9eb0dbc0e358d0d1e3759753fa40
ToppCellCOVID-19-Endothelial_cells-Inflamed_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

JCAD GPR4 SYNE1 PECAM1

6.48e-05193504979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KMT2C ARPP21 VPS13C DGKG

6.48e-05193504a6a864644e1b80b7417ea0a27281e79068a3fd3d
ToppCell367C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

JCAD GPR4 PECAM1 SEMA3G

6.48e-05193504d4b58eee97043b4337ec36c40f9af6499d864df9
ToppCell390C-Endothelial_cells-Endothelial-B_(Artery)|390C / Donor, Lineage, Cell class and subclass (all cells)

JCAD GPR4 PECAM1 SEMA3G

6.61e-05194504f8a59bd4609d147d8a706bf606e9e8173c9992a3
ToppCell390C-Endothelial_cells-Endothelial-B_(Artery)-|390C / Donor, Lineage, Cell class and subclass (all cells)

JCAD GPR4 PECAM1 SEMA3G

6.61e-0519450404b1acc2e879feafb43f75435281c5acd8d23be2
ToppCell(6)_Endothelial-B_(Artery)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

JCAD GPR4 PECAM1 SEMA3G

6.61e-051945040cf4e67d4024652794b5bfdd4a71a7d98900b4c8
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JCAD GPR4 PECAM1 SEMA3G

6.61e-05194504ea5e1bc8d9e27cabfe1fb833ca47ec0893593b12
ToppCellCOVID-19-kidney-Glomerular_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

JCAD SYNE1 PECAM1 SYNE2

6.61e-05194504660535b492445063d965095a50e1e299ce04c50a
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

JCAD SYNE1 PECAM1 SEMA3G

6.61e-0519450440842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JCAD GPR4 PECAM1 SEMA3G

6.61e-05194504cceb7c88492bb6cd531e1c2651638da1ddf30931
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH3 SYNE1 SYNE2 CFAP69

6.74e-05195504fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell367C-Endothelial_cells-Endothelial-E-|367C / Donor, Lineage, Cell class and subclass (all cells)

JCAD GPR4 PECAM1 SEMA3G

6.74e-0519550465fc50e3818e902028fc4226070fa57609c66b9c
ToppCell367C-Endothelial_cells-Endothelial-E|367C / Donor, Lineage, Cell class and subclass (all cells)

JCAD GPR4 PECAM1 SEMA3G

6.74e-051955043b79e6bb525b17192ecec9e1227a29c419968144
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

DNAH3 SYNE1 SYNE2 CFAP69

6.74e-05195504eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 SYNE1 CFAP69 IQUB

6.74e-051955043486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

JCAD SYNE1 PECAM1 SYNE2

6.74e-0519550450a193475db1bb1e05b8590225a553688c372c14
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-Late_cap|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

JCAD GPR4 PECAM1 SEMA3G

6.74e-05195504dfc5da514fb34a2c318a5c4c61f44049fa43960e
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD GPR4 PECAM1 SEMA3G

6.88e-05196504ae46d4b00be92e64e46252dcc156161b171eded4
ToppCelldroplet-Bladder-nan-24m-Endothelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 MYH11 PECAM1 DGKG

6.88e-051965049a90dd26e7a43e3fd55e7c5d8354cfa4cdd5a6cc
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD SYNE1 PECAM1 SEMA3G

6.88e-05196504d323f7dc41380446e5967c69832bea88351a9331
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH3 SYNE1 SYNE2 CFAP69

6.88e-05196504af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOVID-19-lung-Capillary_Aerocytes|COVID-19 / Disease (COVID-19 only), tissue and cell type

JCAD SYNE1 PECAM1 SYNE2

6.88e-0519650449cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCellwk_08-11-Endothelial-Blood_vessel_endothelial-Early_cap|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

JCAD GPR4 PECAM1 SEMA3G

6.88e-051965040f00aac6dac699507ce336020b2e96fd192de0be
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH3 SYNE1 SYNE2 CFAP69

6.88e-051965046d02d494196e3f857d53eea46d9419690d43beca
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 SYNE1 CFAP69 IQUB

6.88e-05196504d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JCAD GPR4 PECAM1 SEMA3G

6.88e-05196504ed818de15f84f7f28bd06fd69d7876710da232a0
ToppCelldroplet-Bladder-nan-24m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR4 MYH11 PECAM1 DGKG

6.88e-0519650404dfef1bd4ebb0e9469ae80024dc177e469a2560
ToppCellCOVID-19-lung-Capillary_Aerocytes|lung / Disease (COVID-19 only), tissue and cell type

JCAD SYNE1 PECAM1 SYNE2

6.88e-051965044ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCell3'-Distal_airway-Endothelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JCAD GPR4 PECAM1 SEMA3G

7.01e-051975049ffb823c0f3f23cc85f9fd3ca24f77817e90bd86
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JCAD GPR4 PECAM1 SEMA3G

7.01e-0519750462c0a90869431e582bb7bb329e0b0cc59123d3d1
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 SYNE1 CFAP69 IQUB

7.01e-051975046865f4831eb23794fb88a8649d48d497bbae3f44
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 SYNE1 CFAP69 IQUB

7.01e-0519750471fea4aa6ce96c7693fa94792d08770622873850
ToppCellBronchial_Biopsy-Mesenchymal-Smooth_muscle|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

GPR4 MYH11 DGKG SEMA3G

7.01e-0519750498f0184a09563a544f0c2d4df22c9db2fbc95019
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 SYNE1 CFAP69 IQUB

7.01e-05197504e453d085182364ca347cbcc9dc995c62c3353016
Drughydantoin-5-propionic acid

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.41e-0721524CID000000782
DrugAZFd

RBMY1A1 RBMY1D RBMY1B RBMY1E

2.07e-0723524CID000196489
DrugSU6668

RBMY1A1 PECAM1 RBMY1D RBMY1B RBMY1E

5.52e-0770525CID000206042
DrugVistar

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.35e-0636524CID000040896
Drug2-chlorodideoxyadenosine

RBMY1A1 RBMY1D RBMY1B RBMY1E

2.79e-0643524CID000072194
Drug2-oyl

GPR4 RBMY1A1 RBMY1D RBMY1B RBMY1E

4.15e-06105525CID000657137
DrugPKI166

RBMY1A1 RBMY1D RBMY1B RBMY1E

4.37e-0648524CID006918403
DrugHgCl

RBMY1A1 RBMY1D RBMY1B RBMY1E

4.75e-0649524CID000024182
Drugcarbonyl sulfide

SYNE1 RBMY1A1 RBMY1D RBMY1B RBMY1E

6.76e-06116525CID000010039
Drugazafagomine

RBMY1A1 RBMY1D RBMY1B RBMY1E

8.74e-0657524CID011957435
Drugthioglycolate

RBMY1A1 RBMY1D RBMY1B RBMY1E

1.67e-0567524CID000001133
Drugp11-13

RBMY1A1 RBMY1D RBMY1B RBMY1E

2.61e-0575524CID000015759
Drugoligoadenylate

SYNE1 RBMY1A1 RBMY1D RBMY1B RBMY1E

2.93e-05157525CID000107918
Drugbipy

RBMY1A1 RBMY1D RBMY1B RBMY1E

7.16e-0597524CID000001474
Drughaloperidol; Up 200; 10uM; MCF7; HG-U133A

GPR4 DNAH3 ELMO2 SEMA3G ATP12A

9.25e-05200525418_UP
Drug1,3,4-thiadiazole

ANPEP SYNE1

1.07e-047522CID000119391
DiseaseAutosomal dominant Emery-Dreifuss muscular dystrophy

SYNE1 SYNE2

1.36e-054452cv:CN293514
DiseaseAutosomal Recessive Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

2.27e-055452C1450051
DiseaseAutosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)

SYNE1 SYNE2

2.27e-055452C0410190
DiseaseEmery-Dreifuss muscular dystrophy

SYNE1 SYNE2

3.40e-056452cv:C0410189
DiseaseMuscular Dystrophy, Emery-Dreifuss

SYNE1 SYNE2

3.40e-056452C0410189
DiseaseX-Linked Emery-Dreifuss Muscular Dystrophy

SYNE1 SYNE2

4.75e-057452C0751337
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE1 SYNE2

1.49e-0412452DOID:11726 (implicated_via_orthology)
Diseaseperceived unattractiveness to mosquitos measurement

RAPGEF6 CDC40 CTNNA2

1.84e-0472453EFO_0008380
Disease3-hydroxy-1-methylpropylmercapturic acid measurement

RTL3 CNTNAP4 CTNNA2 ACAP2 PCDH7

1.94e-04352455EFO_0007015
Diseasewaist-hip ratio

JCAD MYH11 ARPP21 KIDINS220 SYNE2 DGKG TRIP12 IQUB

4.75e-041226458EFO_0004343
Diseasebody weight

RTL3 VPS13C CNTNAP4 DGKG ULK4 CTNNA2 TRIP12 PCDH7

5.73e-041261458EFO_0004338
Diseasebreast milk measurement

CYRIA ULK4 PCDH7

5.73e-04106453EFO_0009092
Diseasemean platelet volume

JCAD CYRIA MYH11 PECAM1 SYNE2 PSMD2 ACAP2

8.32e-041020457EFO_0004584
Diseaseplatelet component distribution width

JCAD CYRIA SYNE1 PECAM1 PSMD2 BRWD1

9.58e-04755456EFO_0007984
DiseasePapillary Renal Cell Carcinoma

PRCC SYNE2 FMN2

9.90e-04128453C1306837
DiseaseRenal Cell Carcinoma

PRCC SYNE2 FMN2

9.90e-04128453C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

PRCC SYNE2 FMN2

9.90e-04128453C1266043
DiseaseChromophobe Renal Cell Carcinoma

PRCC SYNE2 FMN2

9.90e-04128453C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

PRCC SYNE2 FMN2

9.90e-04128453C1266044
DiseaseHereditary Diffuse Gastric Cancer

KMT2C FSD1 CTNNA2 NOTCH2

1.03e-03293454C1708349
DiseaseStomach Neoplasms

KMT2C FSD1 CTNNA2 NOTCH2

1.08e-03297454C0038356
DiseaseMalignant neoplasm of stomach

KMT2C FSD1 CTNNA2 NOTCH2

1.12e-03300454C0024623
DiseaseBladder Neoplasm

KMT2C ANPEP NOTCH2

1.28e-03140453C0005695
DiseaseMalignant neoplasm of urinary bladder

KMT2C ANPEP NOTCH2

1.31e-03141453C0005684
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

PRCC SYNE2 FMN2

1.50e-03148453C0279702

Protein segments in the cluster

PeptideGeneStartEntry
RAAQMFPSESKQKDD

ANKRD30B

556

Q9BXX2
QEPDVVNFDFKNMAD

CNTNAP4

1086

Q9C0A0
QMQAADARKSFPCFD

ANPEP

211

P15144
DFSQMASNNPEKLNR

ACAP2

756

Q15057
RMDAVAAKVPNDGQN

CECR2

1281

Q9BXF3
KEDNQQNRMHPFRDD

ARPP21

261

Q9UBL0
ENPADAKNAAKDMNG

RBMY1A1

56

P0DJD3
ENPADAKNAAKDMNG

RBMY1B

56

A6NDE4
ENPADAKNAAKDMNG

RBMY1C

56

P0DJD4
ENPADAKNAAKDMNG

RBMY1D

56

P0C7P1
ENPADAKNAAKDMNG

RBMY1E

56

A6NEQ0
ENPADAKNAAKDMNG

RBMY1F

56

Q15415
PSKMNEFLENFEKNA

NIPSNAP3A

46

Q9UFN0
ANRDMQDNKEETPLF

NOTCH2

2001

Q04721
FDELKMRNPAIQNDF

CYRIA

141

Q9H0Q0
LDPNCEKMFDNGNFR

FOXI3

221

A8MTJ6
PANRANQNFDEMEGI

KIDINS220

1691

Q9ULH0
PEDQMVFSEQAANKD

KMT2C

551

Q8NEZ4
DARDKNSAFNPMASD

KMT2C

1596

Q8NEZ4
QAMDSEDFPQAAKQI

FSD1

106

Q9BTV5
AAKNAADMVLLDDNF

ATP12A

756

P54707
RDMDNNDLKPSADQK

JCAD

596

Q9P266
DKNDNDPKFMQDVFT

PCDH7

631

O60245
NDDVRNHAMKPINDN

PECAM1

666

P16284
AMNRFKAALEEANGE

MLKL

61

Q8NB16
RFLASDKPQEMANAS

GPR4

306

P46093
SNMAEKQAPAEDQVA

DGKG

126

P49619
ARPQSKVAQDNMDVF

CTNNA2

471

P26232
AADQPRMAEKLQEAN

DNAH3

1136

Q8TD57
APEDKRQDMANAFAQ

ELMO2

246

Q96JJ3
IEKPNNFMKDSASQD

BRWD1

1876

Q9NSI6
EKQYAMQRPNDDSLA

IQUB

96

Q8NA54
DDEAQDVFKPMDLNR

CFAP69

36

A5D8W1
EPQDLFQASQMKFED

FMN2

1561

Q9NZ56
FQKDLAARAMNVDPS

SALL3

1196

Q9BXA9
LARMAANVENPASAD

KIF13B

1321

Q9NQT8
VLQDTFDNPENMKDA

RTL3

311

Q8N8U3
QDLQDIFDPSRNMAK

RAPGEF6

981

Q8TEU7
AFQDDAANAPLEFKM

PRCC

311

Q92733
EEMDKNKNLFSQAFP

SYNE1

6431

Q8NF91
FQNMAFQDHPEKSEQ

SYNE2

3606

Q8WXH0
ESDADDKMRQLNGFQ

SYNE2

6276

Q8WXH0
ENMAPGENKRFAADI

PSMD2

111

Q13200
FNPDEDKQNLFVAGM

CDC40

381

O60508
FESPADAKAAARDMN

RBMXL2

56

O75526
QDDIKNQQPASFMRE

CCDC15

671

Q0P6D6
NQMAEKADGFVNLPD

CNK3/IPCEF1

541

G9CGD6
FKKERNTDQASMPDN

MYH11

361

P35749
MAENFVNDPENEINR

XIRP2

3146

A4UGR9
FESPADAKAAARDMN

RBMXL3

56

Q8N7X1
LDNNFEVNFDKDPME

VPS13C

3156

Q709C8
AFGENDNRENKAMPC

ZBTB39

331

O15060
FVMAARIPENSDQDN

SEMA3G

226

Q9NS98
RRQEKMADPESNQEA

TRIP12

351

Q14669
DNKNNNEMAAPLLFS

ULK4

1096

Q96C45
NFAPNFKESEMNAIA

NACC1

446

Q96RE7