Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 RPP38 ERVK-7 ERVK-10 DICER1 ERVK-8 ERVK-11

4.04e-1037957GO:0016891
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

9.90e-1011955GO:0004523
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 RPP38 ERVK-7 ERVK-10 DICER1 ERVK-8 ERVK-11

2.03e-0946957GO:0016893
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

4.24e-0914955GO:0003964
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

4.20e-0821955GO:0035613
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-6 RPP38 ERVK-7 ERVK-10 DICER1 ERVK-8 ERVK-11

9.67e-0879957GO:0004521
GeneOntologyMolecularFunctionRNA nuclease activity

ERVK-6 RPP38 ERVK-7 ERVK-10 DICER1 ERVK-8 PARN ERVK-11

2.78e-07136958GO:0004540
GeneOntologyMolecularFunctionendonuclease activity

ERVK-6 RPP38 ERVK-7 ERVK-10 DICER1 N4BP2 ERVK-8 ERVK-11

2.78e-07136958GO:0004519
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18

8.47e-0737955GO:0004190
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

9.72e-0738955GO:0034061
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18

9.72e-0738955GO:0070001
GeneOntologyMolecularFunctionnuclease activity

ERVK-6 RPP38 ERVK-7 ERVK-10 DICER1 N4BP2 ERVK-8 PARN ERVK-11

1.57e-06231959GO:0004518
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERVK-6 TTF2 CHD1 ERVK-7 ERVK-10 DICER1 N4BP2 ERVK-8 ERVK-11

4.42e-06262959GO:0140097
GeneOntologyMolecularFunctionnucleotidyltransferase activity

ERVK-6 NMNAT1 PARP3 ERVK-7 ERVK-10 ERVK-8 ERVK-11

8.14e-06152957GO:0016779
GeneOntologyMolecularFunctionco-SMAD binding

USP9Y SMAD2 SMAD3

2.22e-0512953GO:0070410
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

ERVK-6 MYH3 MYH8 PPP1R12A RPP38 ERVK-7 ERVK-10 PDE10A DICER1 PTPRJ N4BP2 ERVK-8 PARN ERVK-11

2.71e-058079514GO:0016788
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

ERVK-6 TTF2 RPP38 CHD1 ERVK-7 ERVK-10 DICER1 DDX27 N4BP2 ERVK-8 PARN ERVK-11

5.51e-056459512GO:0140640
GeneOntologyMolecularFunctiondenatured protein binding

HSPA1A HSPA1B

6.70e-053952GO:0031249
GeneOntologyMolecularFunctionI-SMAD binding

SMURF1 SMAD2 SMAD3

6.76e-0517953GO:0070411
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

ERVK-6 RPP38 ERVK-7 ERVK-10 DICER1 DDX27 ERVK-8 PARN ERVK-11

1.67e-04417959GO:0140098
GeneOntologyMolecularFunctiondeath receptor agonist activity

HSPA1A HSPA1B

2.22e-045952GO:0038177
GeneOntologyMolecularFunctionR-SMAD binding

SMURF1 SMAD2 SMAD3

2.51e-0426953GO:0070412
GeneOntologyMolecularFunctionATP-dependent protein disaggregase activity

HSPA1A HSPA1B

3.32e-046952GO:0140545
GeneOntologyMolecularFunctionC3HC4-type RING finger domain binding

HSPA1A HSPA1B

3.32e-046952GO:0055131
GeneOntologyMolecularFunctiontransforming growth factor beta receptor binding

SMURF1 SMAD2 SMAD3

4.26e-0431953GO:0005160
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

ERVK-6 NMNAT1 PARP3 ERVK-7 ERVK-10 AURKA N4BP2 AK5 ERVK-8 ERVK-11 ULK2 PLK4 MUSK

4.90e-049389513GO:0016772
GeneOntologyMolecularFunctiontranscription regulator inhibitor activity

HEXIM1 HSPA1A HSPA1B

6.65e-0436953GO:0140416
GeneOntologyMolecularFunctionSMAD binding

SMURF1 USP9Y SMAD2 SMAD3

7.58e-0486954GO:0046332
GeneOntologyMolecularFunctiondisordered domain specific binding

HSPA1A HSPA1B SMAD2

8.42e-0439953GO:0097718
GeneOntologyMolecularFunctioncAMP response element binding

ATF7 ATF2

1.43e-0312952GO:0035497
GeneOntologyMolecularFunctionactin binding

MYH3 MYH8 CALD1 RUSC1 DST SYNE2 PLEKHH2 EPB41

2.03e-03479958GO:0003779
GeneOntologyMolecularFunctionphosphatase regulator activity

PPP2R2D PPP1R12A PPP2R2B PPP1R2C

2.08e-03113954GO:0019208
GeneOntologyMolecularFunctiontranscription coactivator binding

ATF7 TFAM SMAD3

2.17e-0354953GO:0001223
GeneOntologyMolecularFunctionprotein-containing complex destabilizing activity

HSPA1A HSPA1B

2.26e-0315952GO:0140776
GeneOntologyMolecularFunctionATP-dependent activity

TTF2 MYH3 MYH8 CHD1 DICER1 DDX27 HSPA1A HSPA1B DNAH8

2.60e-03614959GO:0140657
GeneOntologyMolecularFunctionprotein kinase binding

ATF7 PPP1R12A SPG11 TRIM21 ATF2 AURKA CD4 PTPRJ PARN MUSK SMAD3

2.87e-038739511GO:0019901
GeneOntologyMolecularFunctionmisfolded protein binding

HSPA1A HSPA1B

3.26e-0318952GO:0051787
GeneOntologyMolecularFunctionzinc ion binding

ERVK-6 TTF2 TRIM4 TRIM21 ERVK-7 ERVK-10 TRIM29 CD4 ERVK-8 ERVK-11 SMAD3

3.36e-038919511GO:0008270
GeneOntologyMolecularFunctionclathrin binding

LDLRAP1 CLTB SCLT1

3.37e-0363953GO:0030276
GeneOntologyMolecularFunctiondeath receptor activity

HSPA1A HSPA1B

4.43e-0321952GO:0005035
GeneOntologyMolecularFunctionATP hydrolysis activity

MYH3 MYH8 CHD1 DDX27 HSPA1A HSPA1B DNAH8

5.10e-03441957GO:0016887
GeneOntologyMolecularFunctioncadherin binding

CALD1 SWAP70 KTN1 TRIM29 PTPRJ HSPA1A

5.62e-03339956GO:0045296
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

2.33e-0913955GO:0015074
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-6 ERVK-7 ERVK-10 SYCP1 ERVK-8 ERVK-11

8.54e-0848956GO:0000731
GeneOntologyBiologicalProcessRNA-templated DNA biosynthetic process

ERVK-6 ERVK-7 ERVK-10 ERVK-8 PARN ERVK-11

2.31e-0683956GO:0006278
GeneOntologyBiologicalProcessDNA biosynthetic process

ERVK-6 PARP3 ERVK-7 ERVK-10 SYCP1 ERVK-8 PARN ERVK-11

7.56e-06218958GO:0071897
GeneOntologyBiologicalProcessDNA metabolic process

ERVK-6 TTF2 NMNAT1 SWAP70 PARP3 ERVK-7 ERVK-10 DICER1 KMT5B N4BP2 SYCP1 ERVK-8 PARN ERVK-11 HSPA1A HSPA1B TADA3

7.99e-0610819517GO:0006259
GeneOntologyBiologicalProcessviral process

ERVK-6 CHD1 TRIM21 ERVK-7 ERVK-10 DICER1 HEXIM1 CD4 ERVK-8 HSPA1A HSPA1B

9.46e-064649511GO:0016032
GeneOntologyBiologicalProcessDNA repair

ERVK-6 TTF2 PARP3 ERVK-7 ERVK-10 KMT5B SYCP1 ERVK-8 ERVK-11 HSPA1A HSPA1B TADA3

4.22e-056489512GO:0006281
GeneOntologyBiologicalProcessregulation of mitotic spindle organization

MAP9 PARP3 HSPA1A HSPA1B

4.98e-0544954GO:0060236
GeneOntologyBiologicalProcessDNA recombination

ERVK-6 SWAP70 PARP3 ERVK-7 ERVK-10 KMT5B SYCP1 ERVK-8 ERVK-11

5.06e-05368959GO:0006310
GeneOntologyBiologicalProcessorganelle assembly

MAP9 MYH3 ERICH3 SMURF1 SPG11 DICER1 SEPTIN6 AURKA SYNE2 SSX2IP SCLT1 HSPA1A HSPA1B DNAH8 ULK2 PLK4

5.94e-0511389516GO:0070925
GeneOntologyBiologicalProcessregulation of spindle organization

MAP9 PARP3 HSPA1A HSPA1B

7.04e-0548954GO:0090224
GeneOntologyBiologicalProcessmicrotubule-based process

MAP9 PPP1R12A KTN1 PARP3 SPG11 QRICH2 DICER1 AURKA DST SYNE2 SSX2IP HSPA1A HSPA1B DNAH8 PLK4

9.47e-0510589515GO:0007017
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

MAP9 PPP1R12A PARP3 DICER1 AURKA DST SYNE2 SSX2IP HSPA1A HSPA1B DNAH8 PLK4

1.15e-047209512GO:0000226
GeneOntologyBiologicalProcessDNA damage response

ERVK-6 TTF2 PARP3 ERVK-7 ERVK-10 ATF2 KMT5B SYCP1 ERVK-8 ZBTB40 ERVK-11 HSPA1A HSPA1B TADA3

1.22e-049599514GO:0006974
GeneOntologyBiologicalProcessmotor neuron apoptotic process

SPG11 ATF2 MUSK

2.85e-0428953GO:0097049
GeneOntologyBiologicalProcesscellular heat acclimation

HSPA1A HSPA1B

3.11e-046952GO:0070370
GeneOntologyCellularComponentcentrosome

PPP1R12A PARP3 TTC23L CCDC141 AURKA CCDC112 AK5 KIAA1217 SSX2IP SCLT1 HSPA1A HSPA1B PLK4

3.99e-057709413GO:0005813
GeneOntologyCellularComponentcentriole

PARP3 AURKA SCLT1 HSPA1A HSPA1B PLK4

1.27e-04172946GO:0005814
GeneOntologyCellularComponentmicrotubule organizing center

PPP1R12A PARP3 TTC23L CCDC141 AURKA CCDC112 AK5 KIAA1217 SSX2IP SCLT1 HSPA1A HSPA1B PLK4

2.34e-049199413GO:0005815
GeneOntologyCellularComponentheteromeric SMAD protein complex

SMAD2 SMAD3

5.50e-048942GO:0071144
DomainTF_CRE-BP1-typ

ATF7 ATF2

6.56e-053882IPR016378
DomainPP2A_PR55

PPP2R2D PPP2R2B

1.31e-044882IPR000009
DomainPP2A_PR55_CS

PPP2R2D PPP2R2B

1.31e-044882IPR018067
DomainPR55_2

PPP2R2D PPP2R2B

1.31e-044882PS01025
DomainPR55_1

PPP2R2D PPP2R2B

1.31e-044882PS01024
DomainSpectrin

CCDC141 DST SYNE2

1.67e-0423883PF00435
DomainSpectrin_repeat

CCDC141 DST SYNE2

3.38e-0429883IPR002017
DomainDwarfin

SMAD2 SMAD3

6.03e-048882IPR013790
DomainDWB

SMAD2 SMAD3

6.03e-048882SM00524
DomainMH2

SMAD2 SMAD3

6.03e-048882PS51076
DomainMH1

SMAD2 SMAD3

6.03e-048882PS51075
Domain-

SMAD2 SMAD3

6.03e-0488823.90.520.10
DomainMAD_homology_MH1

SMAD2 SMAD3

6.03e-048882IPR013019
DomainMH2

SMAD2 SMAD3

6.03e-048882PF03166
DomainSMAD_dom_Dwarfin-type

SMAD2 SMAD3

6.03e-048882IPR001132
DomainMYTH4

PLEKHH1 PLEKHH2

7.73e-049882PS51016
DomainMyTH4_dom

PLEKHH1 PLEKHH2

7.73e-049882IPR000857
DomainMyTH4

PLEKHH1 PLEKHH2

7.73e-049882PF00784
DomainMyTH4

PLEKHH1 PLEKHH2

7.73e-049882SM00139
DomainFERM_M

PLEKHH1 PLEKHH2 EPB41

1.33e-0346883PF00373
DomainMAD_homology1_Dwarfin-type

SMAD2 SMAD3

1.40e-0312882IPR003619
DomainDWA

SMAD2 SMAD3

1.40e-0312882SM00523
DomainMH1

SMAD2 SMAD3

1.40e-0312882PF03165
Domain-

PLEKHH1 PLEKHH2 EPB41

1.59e-03498831.20.80.10
DomainFERM_central

PLEKHH1 PLEKHH2 EPB41

1.59e-0349883IPR019748
DomainFERM_domain

PLEKHH1 PLEKHH2 EPB41

1.59e-0349883IPR000299
DomainHelicase_C

TTF2 CHD1 DICER1 DDX27

1.64e-03107884PF00271
DomainHELICc

TTF2 CHD1 DICER1 DDX27

1.64e-03107884SM00490
DomainFERM_1

PLEKHH1 PLEKHH2 EPB41

1.69e-0350883PS00660
DomainFERM_2

PLEKHH1 PLEKHH2 EPB41

1.69e-0350883PS00661
DomainFERM_3

PLEKHH1 PLEKHH2 EPB41

1.69e-0350883PS50057
DomainBand_41_domain

PLEKHH1 PLEKHH2 EPB41

1.69e-0350883IPR019749
DomainB41

PLEKHH1 PLEKHH2 EPB41

1.69e-0350883SM00295
DomainFERM/acyl-CoA-bd_prot_3-hlx

PLEKHH1 PLEKHH2 EPB41

1.69e-0350883IPR014352
DomainHelicase_C

TTF2 CHD1 DICER1 DDX27

1.70e-03108884IPR001650
DomainHELICASE_CTER

TTF2 CHD1 DICER1 DDX27

1.76e-03109884PS51194
DomainHELICASE_ATP_BIND_1

TTF2 CHD1 DICER1 DDX27

1.76e-03109884PS51192
DomainDEXDc

TTF2 CHD1 DICER1 DDX27

1.76e-03109884SM00487
DomainHelicase_ATP-bd

TTF2 CHD1 DICER1 DDX27

1.82e-03110884IPR014001
DomainMyosin_N

MYH3 MYH8

2.21e-0315882PF02736
DomainMyosin_N

MYH3 MYH8

2.21e-0315882IPR004009
DomainHSP70

HSPA1A HSPA1B

2.52e-0316882PF00012
DomainSMAD_dom-like

SMAD2 SMAD3

2.52e-0316882IPR017855
Domain-

SMAD2 SMAD3

2.52e-03168822.60.200.10
DomainHSP70_2

HSPA1A HSPA1B

2.85e-0317882PS00329
DomainHSP70_3

HSPA1A HSPA1B

2.85e-0317882PS01036
DomainHSP70_1

HSPA1A HSPA1B

2.85e-0317882PS00297
DomainMyosin_tail_1

MYH3 MYH8

3.20e-0318882PF01576
DomainMyosin_tail

MYH3 MYH8

3.20e-0318882IPR002928
DomainHsp_70_fam

HSPA1A HSPA1B

3.20e-0318882IPR013126
DomainMyosin-like_IQ_dom

MYH3 MYH8

3.56e-0319882IPR027401
Domain-

MYH3 MYH8

3.56e-03198824.10.270.10
DomainBBOX

TRIM4 TRIM21 TRIM29

4.23e-0369883SM00336
DomainCa/CaM-dep_Ca-dep_prot_Kinase

AURKA ULK2 PLK4

4.23e-0369883IPR020636
Domain-

TRIM4 TRIM21 TRIM29

4.59e-03718834.10.45.10
PathwayREACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION

E2F5 SMAD2 SMAD3

2.47e-0426673MM14878
PathwayREACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING

SMURF1 SMAD2 SMAD3

2.47e-0426673M628
PathwayREACTOME_SIGNALING_BY_NODAL

SMAD2 SMAD3

3.30e-046672MM14517
PathwayKEGG_ADHERENS_JUNCTION

PTPRJ SSX2IP SMAD2 SMAD3

3.96e-0473674M638
PathwayKEGG_TIGHT_JUNCTION

MYH3 MYH8 PPP2R2D PPP2R2B EPB41

4.05e-04132675M11355
PathwayREACTOME_LOSS_OF_FUNCTION_OF_SMAD2_3_IN_CANCER

SMAD2 SMAD3

4.60e-047672M29623
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_CYCLE_GENES

SMAD2 SMAD3

4.60e-047672MM15661
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

SMURF1 E2F5 SMAD2 SMAD3

4.86e-0477674MM14670
PathwayKEGG_MEDICUS_REFERENCE_TGF_BETA_SIGNALING_PATHWAY

SMAD2 SMAD3

6.12e-048672M47415
PathwayKEGG_MEDICUS_REFERENCE_NODAL_SIGNALING_PATHWAY

SMAD2 SMAD3

6.12e-048672M47849
PathwayKEGG_MEDICUS_REFERENCE_ACTIVIN_SIGNALING_PATHWAY

SMAD2 SMAD3

6.12e-048672M47846
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX_IN_CANCER

SMAD2 SMAD3

6.12e-048672M27246
PathwayPID_SMAD2_3NUCLEAR_PATHWAY

E2F5 ATF2 SMAD2 SMAD3

6.17e-0482674M2
PathwayREACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION

E2F5 SMAD2 SMAD3

6.55e-0436673M633
PathwayKEGG_TGF_BETA_SIGNALING_PATHWAY

SMURF1 E2F5 SMAD2 SMAD3

7.39e-0486674M2642
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

MYH3 MYH8 CALD1 PPP2R2D PPP1R12A CHD1 DICER1 HEXIM1 AURKA CD4 DST PARN HSPA1A HSPA1B PLK4

3.00e-08910961536736316
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MAP9 MYH3 MYH8 CALD1 FAM133A PPP1R12A KTN1 ANKRD30B SPG11 PDE10A TFAM DST N4BP2 SYNE2 SYCP1 ANKRD30A DNAH8 CCDC191

7.47e-081442961835575683
Pubmed

Dicer deficiency in proximal tubules exacerbates renal injury and tubulointerstitial fibrosis and upregulates Smad2/3.

DICER1 SMAD2 SMAD3

8.14e-08496330280598
Pubmed

Estrogen inhibits transforming growth factor beta signaling by promoting Smad2/3 degradation.

SMURF1 SMAD2 SMAD3

8.14e-08496320207742
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10

8.14e-08496310469592
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

BDP1 ATF7 MYH3 STARD4 NMNAT1 COX4I1 RPP38 TRIM21 E2F5 DICER1 AURKA PPP2R2B DST VPS35L SERTAD4 ANKRD30A PLK4

8.68e-081293961715342556
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-7 ERVK-18

2.03e-07596312629516
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-11

2.53e-079496621542922
Pubmed

Hepatitis C virus/human interactome identifies SMURF2 and the viral protease as critical elements for the control of TGF-β signaling.

SMURF1 SMAD2 SMAD3

4.05e-07696323781096
Pubmed

CHIP mediates degradation of Smad proteins and potentially regulates Smad-induced transcription.

SMURF1 SMAD2 SMAD3

7.08e-07796314701756
Pubmed

MAP4K4 and WT1 mediate SOX6-induced cellular senescence by synergistically activating the ATF2-TGFβ2-Smad2/3 signaling pathway in cervical cancer.

ATF2 SMAD2 SMAD3

7.08e-07796338383842
Pubmed

E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression.

E2F5 SMAD2 SMAD3

7.08e-07796312150994
Pubmed

Identification of mZnf8, a mouse Krüppel-like transcriptional repressor, as a novel nuclear interaction partner of Smad1.

SMURF1 SMAD2 SMAD3

7.08e-07796312370310
Pubmed

A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.

CALD1 PPP1R12A TRIM21 HEXIM1 KIAA1217 CLTB

9.70e-0711896630979931
Pubmed

Selective compounds enhance osteoblastic activity by targeting HECT domain of ubiquitin ligase Smurf1.

SMURF1 SMAD2 SMAD3

1.13e-06896328881580
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

MYH3 MYH8 KTN1 CCDC141 DST SYNE2 ZBTB40 HSPA1B SMAD2 SMAD3

1.22e-06497961023414517
Pubmed

YAP and TAZ are required for the postnatal development and the maintenance of the structural integrity of the oviduct.

CALD1 DICER1 SMAD2 SMAD3

1.23e-062996432520726
Pubmed

The Smad pathway.

SMURF1 SMAD2 SMAD3

1.69e-06996310708948
Pubmed

Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1).

SMURF1 SMAD2 SMAD3

2.41e-061096315221015
Pubmed

The protein interactome of collapsin response mediator protein-2 (CRMP2/DPYSL2) reveals novel partner proteins in brain tissue.

MAP9 SEPTIN6 PLEKHH1 AK5 CLTB

2.77e-067996525921334
Pubmed

An intrinsic distinction in neuromuscular junction assembly and maintenance in different skeletal muscles.

MYH3 MNX1 MUSK

3.31e-061196311988168
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

ATF7 TTF2 PPP2R2D PPP1R12A KTN1 TRIM29 ATF2 PHF21A CBFA2T2 ZBTB40 SMAD2 SMAD3

4.36e-06857961225609649
Pubmed

Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling.

SMURF1 SMAD2 SMAD3

4.40e-061296319917253
Pubmed

Autophagic degradation of the inhibitory p53 isoform Δ133p53α as a regulatory mechanism for p53-mediated senescence.

CALD1 PPP1R12A CLTB HSPA1A HSPA1B

4.71e-068896525144556
Pubmed

Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways.

SMURF1 SMAD2 SMAD3

5.71e-061396319914168
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

CALD1 SWAP70 KTN1 TRIM21 DST KIAA1217 CLTB HSPA1B

7.32e-0636096833111431
Pubmed

Exercise induces hepatosplanchnic release of heat shock protein 72 in humans.

HSPA1A HSPA1B

7.54e-06296212411538
Pubmed

Molecular cloning and analysis of DNA complementary to three mouse Mr = 68,000 heat shock protein mRNAs.

HSPA1A HSPA1B

7.54e-0629622868009
Pubmed

Up-regulation of inducible heat shock protein-70 expression in multiple sclerosis patients.

HSPA1A HSPA1B

7.54e-06296224328534
Pubmed

Lack of extracellular matrix switches TGF-β induced apoptosis of endometrial cells to epithelial to mesenchymal transition.

SMAD2 SMAD3

7.54e-06296236050359
Pubmed

Receptor-regulated and inhibitory Smads are critical in regulating transforming growth factor beta-mediated Meckel's cartilage development.

SMAD2 SMAD3

7.54e-06296211984875
Pubmed

In vitro transcription of a human hsp 70 heat shock gene by extracts prepared from heat-shocked and non-heat-shocked human cells.

HSPA1A HSPA1B

7.54e-0629623786141
Pubmed

Polycomb determines responses to smad2/3 signaling in embryonic stem cell differentiation and in reprogramming.

SMAD2 SMAD3

7.54e-06296223666711
Pubmed

Characterization of the binding between a 70-kDa heat shock protein, HspA1A, and phosphoinositides.

HSPA1A HSPA1B

7.54e-06296226923070
Pubmed

Phosphorylated Smad2/3 immunoreactivity in sporadic and familial amyotrophic lateral sclerosis and its mouse model.

SMAD2 SMAD3

7.54e-06296218210139
Pubmed

Surface expression of HSP72 by LPS-stimulated neutrophils facilitates gammadeltaT cell-mediated killing.

HSPA1A HSPA1B

7.54e-06296216482515
Pubmed

Effect of hyaluronan oligosaccharides on the expression of heat shock protein 72.

HSPA1A HSPA1B

7.54e-06296211864979
Pubmed

ASAP is a novel substrate of the oncogenic mitotic kinase Aurora-A: phosphorylation on Ser625 is essential to spindle formation and mitosis.

MAP9 AURKA

7.54e-06296217925329
Pubmed

Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis.

SMAD2 SMAD3

7.54e-06296220010874
Pubmed

Hippocampal 72-kDa heat shock protein expression varies according to mice learning performance independently from chronic exposure to stress.

HSPA1A HSPA1B

7.54e-06296215719414
Pubmed

Hsp70 protects from stroke in atrial fibrillation patients by preventing thrombosis without increased bleeding risk.

HSPA1A HSPA1B

7.54e-06296226976620
Pubmed

Inhibition of MuSK expression by CREB interacting with a CRE-like element and MyoD.

ATF2 MUSK

7.54e-06296215964791
Pubmed

Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation.

SMAD2 SMAD3

7.54e-06296216382155
Pubmed

Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70.1 antibody.

HSPA1A HSPA1B

7.54e-06296221187371
Pubmed

Plk4 and Aurora A cooperate in the initiation of acentriolar spindle assembly in mammalian oocytes.

AURKA PLK4

7.54e-06296228972102
Pubmed

Inducible expression of an hsp68-lacZ hybrid gene in transgenic mice.

DST HSPA1B

7.54e-0629622557196
Pubmed

Radiation therapy induces circulating serum Hsp72 in patients with prostate cancer.

HSPA1A HSPA1B

7.54e-06296220430459
Pubmed

Astrocyte targeted overexpression of Hsp72 or SOD2 reduces neuronal vulnerability to forebrain ischemia.

HSPA1A HSPA1B

7.54e-06296220235222
Pubmed

Genetic determinants of HSP70 gene expression following heat shock.

HSPA1A HSPA1B

7.54e-06296220876613
Pubmed

The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange.

HSPA1A HSPA1B

7.54e-06296220223214
Pubmed

Evidence for a role of Smad3 and Smad2 in stabilization of the tumor-derived mutant Smad2.Q407R.

SMAD2 SMAD3

7.54e-06296212700238
Pubmed

Asthma-derived fibroblast to myofibroblast transition is enhanced in comparison to fibroblasts derived from non-asthmatic patients in 3D in vitro culture due to Smad2/3 signalling.

SMAD2 SMAD3

7.54e-06296233245228
Pubmed

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells.

HSPA1A HSPA1B

7.54e-06296220093776
Pubmed

Bacterial infection elicits heat shock protein 72 release from pleural mesothelial cells.

HSPA1A HSPA1B

7.54e-06296223704948
Pubmed

Formation of the definitive endoderm in mouse is a Smad2-dependent process.

SMAD2 SMAD3

7.54e-06296210862745
Pubmed

Smad2-dependent downregulation of miR-30 is required for TGF-β-induced apoptosis in podocytes.

SMAD2 SMAD3

7.54e-06296224086574
Pubmed

Structure and expression of the human gene encoding major heat shock protein HSP70.

HSPA1A HSPA1B

7.54e-0629622858050
Pubmed

Nuclear heat shock protein 72 as a negative regulator of oxidative stress (hydrogen peroxide)-induced HMGB1 cytoplasmic translocation and release.

HSPA1A HSPA1B

7.54e-06296217513788
Pubmed

IL-6 activates HSP72 gene expression in human skeletal muscle.

HSPA1A HSPA1B

7.54e-06296212207910
Pubmed

Inducing heat shock protein 70 expression provides a robust antithrombotic effect with minimal bleeding risk.

HSPA1A HSPA1B

7.54e-06296228837204
Pubmed

Concurrent action of purifying selection and gene conversion results in extreme conservation of the major stress-inducible Hsp70 genes in mammals.

HSPA1A HSPA1B

7.54e-06296229572464
Pubmed

Protective effect of heat shock proteins 70.1 and 70.3 on retinal photic injury after systemic hyperthermia.

HSPA1A HSPA1B

7.54e-06296215988927
Pubmed

Specific Smad2/3 Linker Phosphorylation Indicates Esophageal Non-neoplastic and Neoplastic Stem-Like Cells and Neoplastic Development.

SMAD2 SMAD3

7.54e-06296232705438
Pubmed

Smad2/3 Linker Phosphorylation Is a Possible Marker of Pancreatic Stem/Progenitor Cells in the Regenerative Phase of Acute Pancreatitis.

SMAD2 SMAD3

7.54e-06296228099259
Pubmed

Arsenite Disrupts Zinc-Dependent TGFβ2-SMAD Activity During Murine Cardiac Progenitor Cell Differentiation.

SMAD2 SMAD3

7.54e-06296226354774
Pubmed

Hsp70 (HSPA1) Lysine Methylation Status as a Potential Prognostic Factor in Metastatic High-Grade Serous Carcinoma.

HSPA1A HSPA1B

7.54e-06296226448330
Pubmed

HSP70.1 and -70.3 are required for late-phase protection induced by ischemic preconditioning of mouse hearts.

HSPA1A HSPA1B

7.54e-06296212714332
Pubmed

Inflammation-induced, 3'UTR-dependent translational inhibition of Hsp70 mRNA impairs intestinal homeostasis.

HSPA1A HSPA1B

7.54e-06296219299581
Pubmed

Insights into regulation and function of the major stress-induced hsp70 molecular chaperone in vivo: analysis of mice with targeted gene disruption of the hsp70.1 or hsp70.3 gene.

HSPA1A HSPA1B

7.54e-06296211713291
Pubmed

Heat shock protein 72 (Hsp72) improves long term recovery after focal cerebral ischemia in mice.

HSPA1A HSPA1B

7.54e-06296221108992
Pubmed

Differential effects of Smad2 and Smad3 in regulation of macrophage phenotype and function in the infarcted myocardium.

SMAD2 SMAD3

7.54e-06296235780861
Pubmed

Prion disease is accelerated in mice lacking stress-induced heat shock protein 70 (HSP70).

HSPA1A HSPA1B

7.54e-06296231320473
Pubmed

Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming.

SMAD2 SMAD3

7.54e-06296229174331
Pubmed

Differential expression of AURKA/PLK4 in quiescence and senescence of osteosarcoma U2OS cells.

AURKA PLK4

7.54e-06296232200684
Pubmed

hsp72, a host determinant of measles virus neurovirulence.

HSPA1A HSPA1B

7.54e-06296216971451
Pubmed

SMAD2/3 Phosphorylation Is Downregulated in T Cells in HIV-Infected Patients.

SMAD2 SMAD3

7.54e-06296236226468
Pubmed

Phosphorylation of Smad2/3 at specific linker threonine indicates slow-cycling intestinal stem-like cells before reentry to cell cycle.

SMAD2 SMAD3

7.54e-06296225185661
Pubmed

Increased TGF-β1-mediated suppression of growth and motility in castrate-resistant prostate cancer cells is consistent with Smad2/3 signaling.

SMAD2 SMAD3

7.54e-06296222228025
Pubmed

Heat shock protein 70 promotes lipogenesis in HepG2 cells.

HSPA1A HSPA1B

7.54e-06296229631603
Pubmed

Coordinated post-transcriptional regulation of Hsp70.3 gene expression by microRNA and alternative polyadenylation.

HSPA1A HSPA1B

7.54e-06296221757701
Pubmed

Oocyte-secreted factor activation of SMAD 2/3 signaling enables initiation of mouse cumulus cell expansion.

SMAD2 SMAD3

7.54e-06296217192514
Pubmed

Role of membrane Hsp70 in radiation sensitivity of tumor cells.

HSPA1A HSPA1B

7.54e-06296226197988
Pubmed

Hsp72 overexpression accelerates the recovery from caerulein-induced pancreatitis.

HSPA1A HSPA1B

7.54e-06296222792201
Pubmed

TGFβ pathway deregulation and abnormal phospho-SMAD2/3 staining in hereditary cerebral hemorrhage with amyloidosis-Dutch type.

SMAD2 SMAD3

7.54e-06296228557134
Pubmed

ATF2 and ATF7 Are Critical Mediators of Intestinal Epithelial Repair.

ATF7 ATF2

7.54e-06296231958521
Pubmed

Inhibition of hsp70-1 and hsp70-3 expression disrupts preimplantation embryogenesis and heightens embryo sensitivity to arsenic.

HSPA1A HSPA1B

7.54e-0629629820195
Pubmed

Differential activation of noncanonical SMAD2/SMAD3 signaling by bone morphogenetic proteins causes disproportionate induction of hyaluronan production in immortalized human granulosa cells.

SMAD2 SMAD3

7.54e-06296226992562
Pubmed

Global analysis of Smad2/3-dependent TGF-beta signaling in living mice reveals prominent tissue-specific responses to injury.

SMAD2 SMAD3

7.54e-06296215972691
Pubmed

Surface expression of a C-terminal alpha-helix region in heat shock protein 72 on murine LL/2 lung carcinoma can be recognized by innate immune sentinels.

HSPA1A HSPA1B

7.54e-06296219157555
Pubmed

Heat Shock Protein 70 Is Involved in the Efficiency of Preconditioning with Cyclosporine A in Renal Ischemia Reperfusion Injury by Modulating Mitochondrial Functions.

HSPA1A HSPA1B

7.54e-06296237298493
Pubmed

Enrichment of human ESC-derived multipotent mesenchymal stem cells with immunosuppressive and anti-inflammatory properties capable to protect against experimental inflammatory bowel disease.

SMAD2 SMAD3

7.54e-06296221732483
Pubmed

Smad2 and 3 transcription factors control muscle mass in adulthood.

SMAD2 SMAD3

7.54e-06296219357234
Pubmed

Smad2 and Smad3 have differential sensitivity in relaying TGFβ signaling and inversely regulate early lineage specification.

SMAD2 SMAD3

7.54e-06296226905010
Pubmed

Genetic manipulation of cardiac Hsp72 levels does not alter substrate metabolism but reveals insights into high-fat feeding-induced cardiac insulin resistance.

HSPA1A HSPA1B

7.54e-06296225618331
Pubmed

Cigarette smoke exacerbates mouse allergic asthma through Smad proteins expressed in mast cells.

SMAD2 SMAD3

7.54e-06296221496353
Pubmed

Reduction of Smad2 caused by oxidative stress leads to necrotic death of hypertrophic chondrocytes associated with an endemic osteoarthritis.

SMAD2 SMAD3

7.54e-06296233769459
Pubmed

Extracellular heat shock protein 72 is a marker of the stress protein response in acute lung injury.

HSPA1A HSPA1B

7.54e-06296216679378
Pubmed

Inducible 70 kDa heat shock proteins protect embryos from teratogen-induced exencephaly: Analysis using Hspa1a/a1b knockout mice.

HSPA1A HSPA1B

7.54e-06296219639652
Pubmed

Acceleration of Smad2 and Smad3 phosphorylation via c-Jun NH(2)-terminal kinase during human colorectal carcinogenesis.

SMAD2 SMAD3

7.54e-06296215665291
Pubmed

Effect of mutation of amino acids 246-251 (KRKHKK) in HSP72 on protein synthesis and recovery from hypoxic injury.

HSPA1A HSPA1B

7.54e-06296216100242
InteractionANKRD30A interactions

ANKRD30B ANKRD30A SCLT1

5.07e-068923int:ANKRD30A
InteractionNPM1 interactions

BDP1 NMNAT1 SWAP70 PPP1R12A KTN1 RPP38 CHD1 TRIM21 DICER1 DDX27 HEXIM1 AURKA CD4 SYNE2 SYCP1 ANKRD30A HSPA1A HSPA1B

6.91e-0612019218int:NPM1
InteractionCTNNB1 interactions

COX4I1 PPP1R12A SMURF1 TRIM21 ATF2 TFAM AURKA DST PTPRJ KIAA1217 SYNE2 HSPA1A HSPA1B TADA3 SMAD2 SMAD3

1.21e-0510099216int:CTNNB1
InteractionRAB11A interactions

CALD1 SWAP70 KTN1 TRIM29 ATF2 TFAM DDX27 HEXIM1 COLEC12 DST PTPRJ SYNE2 HSPA1A EPB41

2.30e-058309214int:RAB11A
InteractionFHL1 interactions

SMURF1 TRIM21 ZBTB40 HSPA1A SMAD2 SMAD3

2.78e-05129926int:FHL1
InteractionTRIB2 interactions

PPP1R12A SMURF1 TRIM21 KIAA1217

6.24e-0547924int:TRIB2
InteractionSREBF2 interactions

LDLRAP1 SMURF1 DICER1 HEXIM1 AURKA KMT5B ULK2 SMAD3

6.45e-05297928int:SREBF2
InteractionATF3 interactions

ATF7 CALD1 ATF2 SMAD2 SMAD3

7.08e-0594925int:ATF3
InteractionTOMM70 interactions

COX4I1 DDX27 KMT5B SYNE2 HSPA1A HSPA1B

7.23e-05153926int:TOMM70
InteractionFAM107B interactions

MAP9 CALD1 TADA3

8.46e-0519923int:FAM107B
InteractionSERTAD4 interactions

PPP2R2D PPP2R2B SERTAD4

8.46e-0519923int:SERTAD4
InteractionKDM1A interactions

TRIM4 PPP1R12A RUSC1 TRIM21 SEPTIN6 PHF21A DST N4BP2 KIAA1217 SSX2IP SCLT1 HSPA1A HSPA1B TADA3

8.97e-059419214int:KDM1A
InteractionDCTN1 interactions

TTF2 MAP9 SMURF1 TRIM29 HEXIM1 AURKA DST KIAA1217 HSPA1A EPB41

8.98e-054979210int:DCTN1
InteractionC1orf116 interactions

HEXIM1 SMAD2 SMAD3

9.92e-0520923int:C1orf116
GeneFamilySMAD family

SMAD2 SMAD3

2.89e-048592750
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

PLEKHH1 PLEKHH2 EPB41

5.80e-04505931293
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R2D PPP2R2B

1.07e-0315592696
GeneFamilyMyosin heavy chains

MYH3 MYH8

1.07e-03155921098
GeneFamilyHeat shock 70kDa proteins

HSPA1A HSPA1B

1.38e-0317592583
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM4 TRIM21 TRIM29

3.69e-039559359
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

PPP1R12A CHD1 E2F5 ATF2 AURKA DST CBFA2T2 PLK4 SMAD3

9.38e-07300909M8702
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SWAP70 PPP1R12A CHD1 SPG11 E2F5 ATF2 DICER1 PHF21A AURKA DST SYNE2 PARN SMAD3

7.08e-068569013M4500
CoexpressionGSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_UP

BDP1 PPP1R12A QRICH2 DST SYCP1 ULK2

1.44e-05152906M2964
CoexpressionHIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN

CALD1 RUSC1 HEXIM1 DST PARN

2.73e-05102905M2124
CoexpressionLAMB_CCND1_TARGETS

HSPA1A HSPA1B SMAD3

4.28e-0520903M2935
CoexpressionGSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_UP

KTN1 CCDC141 AURKA SYNE2 SCLT1 PLK4

5.65e-05194906M7467
CoexpressionGSE29618_PRE_VS_DAY7_FLU_VACCINE_PDC_DN

PPP1R12A ATF2 DDX27 PHF21A KMT5B SMAD2

6.69e-05200906M4979
CoexpressionGSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_UP

MAP9 STARD4 PPP1R12A CBFA2T2 SSX2IP EPB41

6.69e-05200906M7489
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

BDP1 TTF2 KTN1 RPP38 CHD1 PDE10A RBM25 N4BP2 SCLT1 PLK4 EPB41

1.23e-055328811Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#5

LDLRAP1 MYH3 PDE10A CD4 ULK2

3.26e-0588885Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_500_K5
ToppCellBasal_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CALD1 CHST9 TRIM29 SERPINB13 DST SYNE2 SERTAD4 SMAD3

6.42e-091969083b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCellBasal_cells|World / lung cells shred on cell class, cell subclass, sample id

CALD1 CHST9 TRIM29 SERPINB13 DST KIAA1217 SYNE2 SERTAD4

6.68e-0919790824360b660000bdfb999d58fbf4e29585a97e1785
ToppCellBronchial_Biopsy|World / Tissue, Lineage and Cell class of Lung Cells from 10X

CHST9 TRIM29 SERPINB13 DST KIAA1217 SYNE2 SERTAD4

1.58e-07198907f5b7013045b61fc56894f80092f799770dde1c8f
ToppCellCOVID-19-T_cells-Tregs|COVID-19 / group, cell type (main and fine annotations)

CCDC141 SEPTIN6 PPP2R2B PTPRJ SYNE2 DNAH8

1.84e-06181906534659cf754326c6a73c0daa30e9d610612a0292
ToppCellT_cells-Treg_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

LDLRAP1 CCDC141 SEPTIN6 CD4 SYNE2 EPB41

2.99e-06197906de5448fcdf4e433fc167496413abe5d0c8a5c6d8
ToppCellmild-CD4+_T_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LDLRAP1 CCDC141 SEPTIN6 AK5 SYNE2 EPB41

3.17e-061999063e4baaf4ee23f257d821194468102c00a8ad2f21
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TRIM29 DST KIAA1217 SYNE2 HSPA1A HSPA1B

3.27e-0620090697f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TRIM29 DST KIAA1217 SYNE2 HSPA1A HSPA1B

3.27e-06200906ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CALD1 HLX HTRA3 SYNE2 PLEKHH2 MUSK

3.27e-06200906ac8a5d71acd4d401995babd233f0d3738e8ad2a5
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LDLRAP1 TRIM29 CCDC141 SYNE2 EPB41

1.48e-051539057480522a47e367f8facc4f5d599fbaf0b5ad4007
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LDLRAP1 TRIM29 CCDC141 SYNE2 EPB41

1.63e-0515690553ded973358e3e48054130131e959f0d1f4ef60f
ToppCellCOVID-Treg|COVID / Condition, Cell_class and T cell subcluster

CALD1 CCDC141 SEPTIN6 SYNE2 EPB41

1.63e-05156905a1dd61d4c9ed8f283f0fcbf875c5fd7807ca370d
ToppCelldroplet-Liver-nan-3m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R12A SEPTIN6 ZBTB40 DNAH8 CCDC191

2.07e-05164905950f87d9dacee45c9004a9bf894543de38f72ee5
ToppCelldroplet-Liver-nan-3m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R12A SEPTIN6 ZBTB40 DNAH8 CCDC191

2.07e-05164905c33910a6d87580902e9e7bd27afe6ea63b5eff8d
ToppCelldroplet-Liver-nan-3m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPP1R12A SEPTIN6 ZBTB40 DNAH8 CCDC191

2.07e-05164905bf0d3ad9016a0b8011a2385bb92f0a4f5edad1d6
ToppCellFetal_29-31_weeks-Epithelial-basal_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CHST9 TRIM29 SERPINB13 SERPINI2 KIAA1217

2.33e-051689056521bead9789d626b86cbd08692c621c5a5aef33
ToppCellBasal_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

CALD1 CHST9 TRIM29 SERPINB13 DST

2.33e-0516890548089fa2d4a0f31a72405717119b767a92571f01
ToppCellControl-T_cells-Tregs|Control / group, cell type (main and fine annotations)

SEPTIN6 PPP2R2B CD4 SYNE2 DNAH8

2.39e-05169905e1e0983f31ec81b3fad5f9c6140d17f03f81a5dc
ToppCellFetal_29-31_weeks-Epithelial-basal_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CHST9 TRIM29 SERPINB13 SERPINI2 KIAA1217

2.39e-05169905c3ee781735a9288ce1822b230d39bb91c1415589
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell-B_activate-7|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERICH3 CALD1 E2F5 CCDC141 DNAH8

2.46e-05170905ee2ee67d90ae4596de8ccd620e37c82cf51651d4
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERICH3 CALD1 E2F5 CCDC141 DNAH8

2.46e-05170905d7ca0c6ce5d2b7de99346f87e07aa7fe728fa08a
ToppCellBAL-Mild-Lymphocyte-B-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERICH3 CALD1 E2F5 CCDC141 DNAH8

2.46e-0517090552787f6d529c285d9f0c04cc022710ead5b89b3f
ToppCellmild_COVID-19-Treg|mild_COVID-19 / disease group, cell group and cell class (v2)

LDLRAP1 CCDC141 SYNE2 PPP1R2C EPB41

2.60e-0517290577af6324c06b67867e7ce07706536fe38de5ed7b
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTF2 PDE10A AURKA SYNE2 DNAH8

2.75e-051749059d5dcd46cf346c381dea68ada6665f7fb68114a3
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTF2 PDE10A AURKA SYNE2 DNAH8

2.75e-0517490553cec5c666c45278a71c21dd9c62a052a97e0fdf
ToppCellEpithelial-basal_cell|World / Lineage, Cell type, age group and donor

CHST9 TRIM29 SERPINB13 SERPINI2 KIAA1217

3.15e-05179905d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCellfacs-Heart-LV-18m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SWAP70 HLX N4BP2 HSPA1B ULK2

3.41e-051829056dff753d65ba45db81f3cc0c9f59e1779d490955
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CALD1 RPP38 HLX COLEC12 PLEKHH2

3.50e-051839055377b4fbd8fdfe68933b4c0965aa9525f7f31591
ToppCell10x5'-blood-Lymphocytic_T_CD4-Tregs|blood / Manually curated celltypes from each tissue

CCDC141 SEPTIN6 CD4 SYNE2 EPB41

3.59e-0518490522c15ce30171c687ab564f4383ae74d38b759272
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAALAD2 TTC23L HTRA3 COLEC12 AK5

3.69e-05185905785c55d39909fac74415f24427979691e7e694e6
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAALAD2 TTC23L HTRA3 COLEC12 AK5

3.69e-0518590597a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COX4I1 CHST9 IRX1 DST SYNE2

3.78e-051869058eafd4bea692f7ef33de27dd53f9d1fe67deaad8
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAALAD2 TTC23L HTRA3 COLEC12 AK5

3.78e-0518690594d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LDLRAP1 CHD1 CD4 SYNE2 EPB41

3.88e-05187905e61c1755531469dd3850c9740474b5ad4e0499c1
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

LDLRAP1 N4BP2 AK5 SYNE2 EPB41

3.98e-05188905b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BDP1 MAP9 SWAP70 E2F5 CCDC191

4.08e-05189905b13f315f617840eb5143a4e8a33a657c20365c21
ToppCellNS-critical-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PDE10A AURKA SSX2IP SERTAD4 PLK4

4.19e-051909057be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-regulatory_T_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CD4 PTPRJ SYNE2 DNAH8 EPB41

4.19e-05190905b69709323a9f1b368b5a4f87295b9f7fd9c9be8e
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

USP9Y DST PLEKHH2 HSPA1A HSPA1B

4.19e-0519090562a3ec1ae0829602b0569cc051210551644f1d46
ToppCellCOPD-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

CCDC141 CD4 PTPRJ SYNE2 DNAH8

4.29e-051919053ae18bc4e3dff49b5d5958da8ebc3f747274b69c
ToppCellfacs-MAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLX HTRA3 COLEC12 SERTAD4 MUSK

4.29e-05191905b4fba92f9bd1354a07fedfca7304a3757e6d5beb
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAALAD2 CALD1 HTRA3 COLEC12 AK5

4.29e-051919056cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCelldroplet-Fat-Gat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAALAD2 CALD1 HTRA3 COLEC12 AK5

4.29e-05191905850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAALAD2 CALD1 HTRA3 COLEC12 AK5

4.29e-051919058b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCell(04)_Pre-ciliated|World / shred by cell type and Timepoint

MAP9 AURKA AK5 DNAH8 PLK4

4.29e-0519190537cf121e6e80760c8519075b7845b9029958a988
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-IPC_like-IPCs|6_mon / Sample Type, Dataset, Time_group, and Cell type.

CALD1 CCDC141 PPP2R2B CBFA2T2 SYNE2

4.40e-05192905bd91bf0ceeac49dc5a18aa2e401244db0ca596ae
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC141 SEPTIN6 CD4 SYNE2 EPB41

4.40e-051929057a90ec9fc8f29216c4828e0cf5d040906456e53b
ToppCellCOVID-19_Severe-Lymphoid_T/NK-Treg|COVID-19_Severe / Disease group, lineage and cell class

CCDC141 SEPTIN6 CD4 SYNE2 EPB41

4.40e-051929053fb4c148dadcf5e79094e55c6bb53ec7bf9d44c8
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CCDC141 SEPTIN6 CD4 SYNE2 EPB41

4.40e-05192905d883b91bbab71673de4858346d3ab33e5fbbf842
ToppCellBAL-Severe-Lymphocyte-T/NK-CD4+_T-Treg-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC141 SEPTIN6 SYNE2 DNAH8 EPB41

4.40e-05192905d85a785a12076e34c404171363a647f318926b18
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-IPC_like|6_mon / Sample Type, Dataset, Time_group, and Cell type.

CALD1 CCDC141 PPP2R2B CBFA2T2 SYNE2

4.40e-0519290518fbf485ad762ba7a9ac3e19bad136b0cf3af3c5
ToppCellBAL-Severe-Lymphocyte-T/NK-CD4+_T-Treg|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCDC141 SEPTIN6 SYNE2 DNAH8 EPB41

4.40e-05192905230f3090607a62bb6d1e1f4b0341ee96d93f1c00
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LDLRAP1 SEPTIN6 CD4 SYNE2 EPB41

4.51e-05193905194b49c152e3e3f599068ec88a7f0af6427b743a
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHST9 HEXIM1 DST KIAA1217 SERTAD4

4.51e-05193905739fb2a57772a800a2e94bdd6c71285bb2c162a7
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LDLRAP1 MAP9 USP9Y SYNE2 EPB41

4.51e-05193905c3cffafc1d40c3d7cf81034d5c51f1c78f5eb0a9
ToppCell21-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

CALD1 HTRA3 COLEC12 DST PLEKHH2

4.62e-051949058fc98d2c9d94f3bc6292265e20ab71c4f1f37bb3
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MAP9 SWAP70 E2F5 CCDC141 CCDC191

4.62e-05194905d852aebf7a763b9a776c4570711f0c759f591910
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BDP1 MAP9 SWAP70 E2F5 CCDC191

4.74e-05195905481989d2e5bd2582da3d86b0155c4d6615317067
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BDP1 MAP9 SWAP70 E2F5 CCDC191

4.74e-051959056108a27523d1b93a7fbe35cb95704a5ad9071e3c
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

HTRA3 COLEC12 PLEKHH2 MUSK SMAD3

4.74e-05195905f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellCOVID-19-Lymphoid-Tregs|Lymphoid / Condition, Lineage and Cell class

CCDC141 CD4 SYNE2 HSPA1A DNAH8

4.74e-051959059ad844d9d5aac39d133ae8ab9c4839300f08064c
ToppCellCOVID-19-Lymphoid-Tregs|COVID-19 / Condition, Lineage and Cell class

CCDC141 SEPTIN6 SYNE2 DNAH8 EPB41

4.74e-05195905284cfff4d59ecc1430997b118de17fee167dcbb1
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

LDLRAP1 CD4 DST SYNE2 EPB41

4.74e-0519590522191d361af136942508f1553ff41a626ed982ad
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

NAALAD2 CALD1 DST PLEKHH2 MUSK

4.74e-05195905aa0add081881d349099d12efca5cdee098038d4e
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAALAD2 CALD1 HTRA3 COLEC12 HSPA1B

4.85e-051969052aa1acea3cefb3dbe3afdb04875c96b927e9d860
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAALAD2 CALD1 HTRA3 COLEC12 HSPA1B

4.85e-0519690559ca204c96149fdff08bc524cfa832a30e60e8a4
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Mesenchymal|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAALAD2 CALD1 HTRA3 COLEC12 HSPA1B

4.85e-05196905d06a29775a41223e02728615af519a18f7e82e8b
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CALD1 HTRA3 DST PLEKHH2 MUSK

4.85e-0519690542e9828222a9663525d571633e8a454c30bfa7f8
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NAALAD2 CALD1 COLEC12 DST PLEKHH2

4.97e-0519790573a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellT_cells-Treg_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

LDLRAP1 CCDC141 CD4 DNAH8 EPB41

4.97e-05197905ec9398ae3577f61d6b1e6aba50ef4261aaaa7610
ToppCell3'-Broncho-tracheal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHST9 TRIM29 SERPINB13 DST SYNE2

4.97e-051979055d33f8a6940431093e927b186fb9b630a89d8ec1
ToppCellEpithelial_cells-Basal_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

CALD1 CHST9 TRIM29 SERPINB13 DST

5.09e-051989054235005c49fc2b29ad3a0ee6b608f0109d04f775
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

STARD4 CHD1 RBM25 CD4 SMAD3

5.09e-0519890561ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCellsevere-Treg|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CCDC141 SEPTIN6 CD4 SYNE2 EPB41

5.09e-05198905377980b9f7d02818e1d145e6884604f8bfacc4f2
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NAALAD2 CALD1 COLEC12 DST PLEKHH2

5.09e-0519890517dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCellIPF-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

SWAP70 CHD1 PDE10A SYNE2 SMAD3

5.09e-05198905b8bd1ba268480f54451648e01631b615a3401144
ToppCellmLN-(1)_T_cell-(15)_Treg|mLN / shred on region, Cell_type, and subtype

CD4 SYNE2 HSPA1A HSPA1B DNAH8

5.09e-05198905d4885f9c59b275e4e50dfcfb51c5351bebba1769
ToppCellmLN-T_cell-Treg|mLN / Region, Cell class and subclass

CD4 SYNE2 HSPA1A HSPA1B DNAH8

5.09e-051989056ce9681d1287632956176239f223e71abb8de44f
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

MAP9 RPP38 CHD1 RBM25 SYNE2

5.09e-0519890576d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRIM29 SERPINB13 DST KIAA1217 SMAD3

5.09e-05198905fc00cb25cdc6c31b7f9d397bc9f9a8f4e9708003
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CALD1 HTRA3 DST PLEKHH2 MUSK

5.09e-05198905f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BDP1 USP9Y RBM25 SYNE2 EPB41

5.22e-05199905f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellPCW_10-12-Mesenchymal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NAALAD2 CALD1 COLEC12 DST PLEKHH2

5.22e-05199905a09292de4c4447b8eee55d401808e43b817321cc
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

CALD1 KTN1 RPP38 RBM25 SYNE2

5.22e-05199905a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CHST9 TRIM29 SERPINB13 KIAA1217 SERTAD4

5.34e-05200905afac850d5a40de0d6f02857cf81a19443d90b1eb
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-Treg|COVID-19_Severe / Disease, condition lineage and cell class

CCDC141 SEPTIN6 CD4 SYNE2 EPB41

5.34e-052009052b363f2a1d08019b6ff0b10419870049063cc1cf
ToppCellParenchyma_COVID-19-Epithelial-TX-Basal_1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

CHST9 TRIM29 SERPINB13 DST SERTAD4

5.34e-05200905592c7c3ded409a9957cbcdc62fcc213fa8eae598
ToppCellBronchus_Control_(B.)-Epithelial-TX|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

ERICH3 CHST9 TRIM29 KIAA1217 SYNE2

5.34e-05200905f5bc7d30aa03dd0f95eb64255bd1a2543be8d327
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BDP1 CHD1 RBM25 SYNE2 EPB41

5.34e-0520090512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_basal-Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TRIM29 SERPINB13 DST KIAA1217 SERTAD4

5.34e-052009059da214f756a03516eaafde00289b90f69623b9f3
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Basal_1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CHST9 TRIM29 SERPINB13 DST SERTAD4

5.34e-052009058cfbde43c5e66269ad128aa5398b1517667d7d36
ToppCellwk_15-18-Mesenchymal-Fibroblast|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NAALAD2 CALD1 COLEC12 DST PLEKHH2

5.34e-052009054f624c3c57d1a84baa86d0830cb1b83ae110bf67
ToppCellBiopsy_Other_PF-Epithelial-Basal|Biopsy_Other_PF / Sample group, Lineage and Cell type

CHST9 TRIM29 SERPINB13 KIAA1217 SERTAD4

5.34e-052009057098ae4b0ea8ba607519eaed8577c577530fc2a1
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal-Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CHST9 TRIM29 SERPINB13 KIAA1217 SERTAD4

5.34e-052009050594ca7bc313b73e1dc800cf058f8f798b0284cb
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

NAALAD2 COLEC12 SERPINB13 DST PLEKHH2

5.34e-05200905bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Basal_1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CHST9 TRIM29 SERPINB13 DST SERTAD4

5.34e-0520090561811380d9252f12f27b7ad4752380b52692677f
ToppCellLung_Parenchyma|World / Location, Disease Group, Cell group, Cell class (2021.03.09)

CALD1 COLEC12 DST HSPA1A HSPA1B

5.47e-0520190591ec5eebe93a3c7b1a33c27e5da949b123b676a8
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAALAD2 HTRA3 COLEC12 PLEKHH2

1.21e-04125904b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-3|TCGA-Brain / Sample_Type by Project: Shred V9

PPP1R12A CHST9 EPB41 SMAD3

1.62e-04135904b128596653a5e3b64ed7f657bbfeda35438e2e48
ToppCellCOVID-Treg-CD4_Treg|COVID / Condition, Cell_class and T cell subcluster

CALD1 CCDC141 SEPTIN6 SYNE2

2.62e-0415390447c649fd4231e507f2d4654ccac61faf21a04eff
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A

PPP1R12A RPP38 SMURF1 CHD1 AURKA KMT5B ZBTB40 PLK4

7.49e-071849182321_DN
Diseasegraft-versus-host disease (biomarker_via_orthology)

HSPA1A HSPA1B

8.54e-055872DOID:0081267 (biomarker_via_orthology)
DiseaseLoeys-Dietz Syndrome

SMAD2 SMAD3

1.79e-047872C2697932
DiseaseDistal arthrogryposis

MYH3 MYH8

3.05e-049872cv:C0265213
DiseaseMajor depression, single episode

HSPA1A HSPA1B

3.05e-049872C0024517
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH3 MYH8

3.81e-0410872DOID:0111269 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH3 MYH8

3.81e-0410872DOID:0111602 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH3 MYH8

3.81e-0410872DOID:0111596 (implicated_via_orthology)
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH3 MYH8

3.81e-0410872DOID:0110454 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH3 MYH8

3.81e-0410872DOID:0080719 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH3 MYH8

3.81e-0410872DOID:3429 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH3 MYH8

3.81e-0410872DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH3 MYH8

3.81e-0410872DOID:0080326 (implicated_via_orthology)
Diseaselevel of Sphingomyelin (d34:0) in blood serum

SYNE2 MUSK

4.65e-0411872OBA_2045176
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

PPP2R2D PPP2R2B

5.56e-0412872DOID:1441 (implicated_via_orthology)
Diseasedistal myopathy (implicated_via_orthology)

MYH3 MYH8

5.56e-0412872DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MYH3 MYH8

5.56e-0412872DOID:2106 (implicated_via_orthology)
DiseaseAlzheimer's disease (is_implicated_in)

TFAM PPP2R2B HSPA1A HSPA1B

6.39e-04132874DOID:10652 (is_implicated_in)
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH3 MYH8

6.56e-0413872DOID:397 (implicated_via_orthology)
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH3 MYH8

8.80e-0415872DOID:0050646 (implicated_via_orthology)
Diseaselevel of Phosphatidylcholine (18:0_20:3) in blood serum

PARN MUSK

1.00e-0316872OBA_2045093
Diseasedilated cardiomyopathy (implicated_via_orthology)

MYH3 MYH8 DICER1

1.73e-0380873DOID:12930 (implicated_via_orthology)
DiseaseLeft Ventricle Remodeling

SMAD2 SMAD3

1.74e-0321872C0600520
DiseaseVentricular Remodeling

SMAD2 SMAD3

1.74e-0321872C0600519
Diseaselevel of Sphingomyelin (d40:2) in blood serum

SYNE2 MUSK

2.09e-0323872OBA_2045181
DiseaseCarcinoma, Pancreatic Ductal

HSPA1A HSPA1B

2.27e-0324872C0887833
DiseaseLynch syndrome (is_implicated_in)

SMAD2 SMAD3

2.27e-0324872DOID:3883 (is_implicated_in)
Diseasedental caries

CHST9 CCDC141 SSX2IP SMAD3

2.31e-03187874EFO_0003819
Diseasecomplement C4b measurement

HSPA1A HSPA1B

2.47e-0325872EFO_0008092
Diseasehypertrophic cardiomyopathy

CCDC141 PHF21A CCDC112

2.57e-0392873EFO_0000538
DiseaseColorectal cancer

AURKA PTPRJ

2.88e-0327872cv:C0346629
DiseaseCOLORECTAL CANCER

AURKA PTPRJ

2.88e-0327872114500
DiseaseNeoplasm of the large intestine

AURKA PTPRJ

2.88e-0327872cv:C0009404
DiseaseC-reactive protein measurement

PPP2R2D HLX SPG11 CCDC168 PDE10A PHF21A RBM25 AK5 ZBTB40 MUSK

2.89e-0312068710EFO_0004458

Protein segments in the cluster

PeptideGeneStartEntry
KEKDQAWKTLKERES

TADA3

411

O75528
KSKLWEESTAQVKDK

ERICH3

701

Q5RHP9
SKTWLDSAKEIKKQV

EPB41

261

P11171
NDKTVKLWKVSERDK

PPP2R2B

111

Q00005
EIKNKFKREEKTNGW

BDP1

336

A6H8Y1
QKLAVEAWKKQKSIE

CCDC112

271

Q8NEF3
AKEIKSQLENQKAKW

ANKRD30B

991

Q9BXX2
SKQKNEESKKRQWAL

AURKA

116

O14965
RLKEEWSLFKEQKKN

SSX2IP

431

Q9Y2D8
DNLSSVKETQKKWAE

ERP29

186

P30040
AKEIKSQLENQKVKW

ANKRD30A

1006

Q9BXX3
NDKTIKLWKISERDK

PPP2R2D

121

Q66LE6
QKRKVWVQSLEKKAE

ATF2

371

P15336
QKRKLWVSSLEKKAE

ATF7

351

P17544
SAEKRKAKWESLQNK

DICER1

1016

Q9UPY3
SSEVKRKKHKDEDWQ

CHD1

136

O14646
SWFQTKEERKKEKIA

DDX27

651

Q96GQ7
VDAKTKAQLDEWKAK

RBM25

161

P49756
TVKTLAKEVWQEKAK

QRICH2

1086

Q9H0J4
KQEEKQIKRKWTEDS

PARN

516

O95453
EKKFREKTKNNWAER

PARP3

126

Q9Y6F1
FWQVSKEEKEKRDKA

LDLRAP1

171

Q5SW96
WRKKRKDAKNNEVSF

PTPRJ

996

Q12913
WEEVKKQLENKKTGS

FAM133A

41

Q8N9E0
WKKQKDKVAELENSE

CD58

56

P19256
EKKKDNLTAVEKWNE

MAP9

551

Q49MG5
WRHSKEAQAQKDKDK

HLX

331

Q14774
CDKVKWDTFVSQEKK

AK5

51

Q9Y6K8
DERDKVQKKTFTKWI

DST

31

Q03001
KWVSNISKTLKDAEK

DST

1451

Q03001
WKRSKKAKEQAAQEA

MNX1

296

P50219
IQDVKRKKSQKWDES

PPP1R2C

36

O14990
KIVATKEWKRNDKIE

KMT5B

211

Q4FZB7
TWEEKKKFDEKQSLR

HEXIM1

171

O94992
DKKKVLDKCQEVISW

HSPA1B

566

P0DMV9
EFWKKTEEAVNKVKI

CBFA2T2

436

O43439
DKKQRNFDKVLSEWK

MYH8

1446

P13535
ETVEKWLKRKNNKSE

PDE10A

41

Q9Y233
AKKDTDWLKEKVQSL

COLEC12

251

Q5KU26
KTWIKSKEKENDLQV

DNAH8

3476

Q96JB1
KQKLLKWSSDLKQER

PHF21A

566

Q96BD5
LKNKFDVTWKQAKDI

HERVK_113

606

P63132
ENKWKVKVDESHKTI

KTN1

1161

Q86UP2
LKNKFDVTWKQAKDI

ERVK-7

606

P63135
LKNKFDVTWKQAKDI

ERVK-6

606

Q9BXR3
KAAKIKEWVTVKLNE

PLEKHH2

126

Q8IVE3
LKNKFDVTWKQAKDI

ERVK-18

606

Q9QC07
LTEFQDKQIKDWKKR

HTRA3

341

P83110
IKAKEWNSAVEKLKS

CCDC141

296

Q6ZP82
IDLIEKKSKNSIQWK

E2F5

101

Q15329
TVKAAWKIEKKRQEE

CCDC191

266

Q8NCU4
NKEAKVSKREKAVWV

CD4

346

P01730
DKKKVLDKCQEVISW

HSPA1A

566

P0DMV8
NKKEFKTADWKTRAD

CCDC168

2736

Q8NDH2
DILNTKKLQWKSKEQ

CCDC168

5041

Q8NDH2
SASQKALKEKEKASW

COX4I1

56

P13073
KKKKNWGADVVAESR

CCDC153

16

Q494R4
KIDTEKTKAEWKTTE

RUSC1

236

Q9BVN2
KWQKEKDRIKSFTTN

TRIM29

291

Q14134
KLEQSKKELTLWEKN

TMC3

346

Q7Z5M5
KEKKTDAKQQVSGWT

RPP38

91

P78345
TWDQCEKKIKELKSR

SYNE2

5811

Q8WXH0
KKENKVTWGARSKDQ

IRX1

186

P78414
RAVSIEKAEKKWEEK

KIAA1217

961

Q5T5P2
VWKVTKDKSNKNRET

SMIM42

46

A0A5F9ZH02
KQRNFDKVLAEWKTK

MYH3

1446

P11055
NNVNESWKKSLRKKE

SERTAD4

326

Q9NUC0
KLKTVKENWKNLSDS

TFAM

181

Q00059
QKDTSKNAWTDTKVK

PLK4

511

O00444
KNAWTDTKVKKNSDA

PLK4

516

O00444
SQTLKRDKEKKNNPW

SEPTIN6

416

Q14141
DKIDLNDWKSNTRLK

SMURF1

636

Q9HCE7
KWVNEKKAQEDKLQT

CALD1

416

Q05682
SLVKDNKWKKTEETQ

CHST9

161

Q7L1S5
NKWKKTEETQEKRRS

CHST9

166

Q7L1S5
SKVTEQEWREKAKKD

CLTB

121

P09497
KVKESNIWKKLSFEE

SPG11

676

Q96JI7
KDAWASDQKVKALKI

VPS35L

196

Q7Z3J2
QWDREFKKENTKEEK

SERPINB13

186

Q9UIV8
QEEKWCEKAVKSLVK

SMAD2

36

Q15796
QEEKWCEKAVKSLVK

SMAD3

26

P84022
IKKWKVSTEAELRQK

SYCP1

116

Q15431
LKNKFDVTWKQAKDI

ERVK-10

606

P10266
LKNKFDVTWKQAKDI

ERVK-8

606

P63133
LKNKFDVTWKQAKDI

ERVK-11

606

Q9UQG0
KGDWKQKFRKEDTQL

SERPINI2

186

O75830
KAANRWKEETKKLTE

SCLT1

586

Q96NL6
SWTNASKKQREKLLE

USP9Y

476

O00507
TLWDANSEVEKKQKS

WDR53

266

Q7Z5U6
WKANTTSNKEKEEIL

TTC23L

146

Q6PF05
EKKAQKKSRQAWLTA

nan

466

Q6ZUG5
AIKRADWKKTVETQK

TRIM21

161

P19474
AKTVQEKAAKIKEWV

PLEKHH1

121

Q9ULM0
KTDWEVAIKSINKKN

ULK2

31

Q8IYT8
DKVEGQKQKLEAWKN

ZBED9

1131

Q6R2W3
EDKWRVAKKTKDVTV

STARD4

26

Q96DR4
ISASDKKKKQEWIQA

SWAP70

286

Q9UH65
EVKNATQWKDKIKSQ

TRIM4

181

Q9C037
TKEDGEKETWKVSNK

ZBTB40

671

Q9NUA8
QEKKEEKEKSTALTW

TTF2

616

Q9UNY4
ENKANSRLAWKEVKK

NAALAD2

706

Q9Y3Q0
RKQWKNKKRESAAVT

MUSK

521

O15146
WKIEKNKISISDSIK

N4BP2

1026

Q86UW6
RKWEDDLKKNSSVNE

PPP1R12A

531

O14974
KRKWTETQDSSQKKS

NMNAT1

126

Q9HAN9