Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprolactin receptor binding

CSH1 CSH2 CSHL1

4.87e-0671053GO:0005148
GeneOntologyMolecularFunctiongrowth hormone receptor binding

CSH1 CSH2 CSHL1

1.65e-05101053GO:0005131
GeneOntologyMolecularFunctionhistone modifying activity

HUWE1 PHF2 KAT2B SUDS3 BRD1 PRDM16 TRIM37 VCPKMT

2.84e-052291058GO:0140993
GeneOntologyMolecularFunctionacyltransferase activity

RGPD4 HECW1 HECTD3 RNF144A UBR4 RGPD1 HUWE1 TTC3 KAT2B UBE2O HHAT RGPD3 BRD1 TRIM37

5.44e-0577510514GO:0016746
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

RGPD4 HECW1 HECTD3 RNF144A UBR4 RGPD1 HUWE1 TTC3 UBE2O RGPD3 TRIM37

8.03e-0551210511GO:0019787
GeneOntologyMolecularFunctionaminoacyltransferase activity

RGPD4 HECW1 HECTD3 RNF144A UBR4 RGPD1 HUWE1 TTC3 UBE2O RGPD3 TRIM37

1.13e-0453210511GO:0016755
GeneOntologyMolecularFunctionSUMO ligase activity

RGPD4 RGPD1 RGPD3

1.51e-04201053GO:0061665
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

RGPD4 HECW1 RNF144A UBR4 RGPD1 HUWE1 UBE2O RGPD3 TRIM37

2.53e-043981059GO:0061659
GeneOntologyMolecularFunctionphosphatase regulator activity

PPP2R2D ELFN2 PPP2R2B PPP2R2C SBF2

3.27e-041131055GO:0019208
GeneOntologyMolecularFunctionhormone receptor binding

CSH1 CSH2 CSHL1

7.51e-04341053GO:0051427
GeneOntologyMolecularFunctionSUMO transferase activity

RGPD4 RGPD1 RGPD3

8.89e-04361053GO:0019789
GeneOntologyBiologicalProcesspositive regulation of glucokinase activity

RGPD4 RGPD1 RGPD3

9.94e-0691033GO:0033133
GeneOntologyBiologicalProcesspositive regulation of hexokinase activity

RGPD4 RGPD1 RGPD3

1.41e-05101033GO:1903301
GeneOntologyBiologicalProcessregulation of kainate selective glutamate receptor activity

KLHL24 NETO1

2.47e-0521032GO:2000312
GeneOntologyBiologicalProcesspositive regulation of steroid hormone biosynthetic process

CSH1 CSH2 CSHL1

3.34e-05131033GO:0090031
GeneOntologyBiologicalProcessregulation of glucokinase activity

RGPD4 RGPD1 RGPD3

3.34e-05131033GO:0033131
GeneOntologyBiologicalProcessregulation of hexokinase activity

RGPD4 RGPD1 RGPD3

4.23e-05141033GO:1903299
GeneOntologyBiologicalProcessregulation of SA node cell action potential

ANK2 RYR2

7.38e-0531032GO:0098907
GeneOntologyBiologicalProcesspositive regulation of hormone biosynthetic process

CSH1 CSH2 CSHL1

1.11e-04191033GO:0046886
GeneOntologyBiologicalProcessNLS-bearing protein import into nucleus

RGPD4 RGPD1 RGPD3

1.30e-04201033GO:0006607
GeneOntologyBiologicalProcessregulation of atrial cardiac muscle cell action potential

ANK2 RYR2

1.47e-0441032GO:0098910
GeneOntologyBiologicalProcessregulation of steroid hormone biosynthetic process

CSH1 CSH2 CSHL1

2.27e-04241033GO:0090030
GeneOntologyBiologicalProcessregulation of AV node cell action potential

ANK2 RYR2

2.45e-0451032GO:0098904
GeneOntologyBiologicalProcessgrowth hormone receptor signaling pathway

CSH1 CSH2 CSHL1

2.89e-04261033GO:0060396
GeneOntologyBiologicalProcesspositive regulation of hormone metabolic process

CSH1 CSH2 CSHL1

2.89e-04261033GO:0032352
GeneOntologyBiologicalProcesscellular response to growth hormone stimulus

CSH1 CSH2 CSHL1

3.24e-04271033GO:0071378
GeneOntologyBiologicalProcesschromatin remodeling

HUWE1 PHF2 KAT2B RUVBL1 SUDS3 ATAD2B BRD1 USP15 TASOR PRDM16 TRIM37 VCPKMT

3.25e-0474110312GO:0006338
GeneOntologyCellularComponentnuclear pore nuclear basket

RGPD4 CETN3 RGPD1 RGPD3

1.74e-06181054GO:0044615
GeneOntologyCellularComponentgrowth hormone receptor complex

CSH1 CSH2 CSHL1

2.44e-0661053GO:0070195
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RGPD4 RGPD1 RGPD3

6.77e-0681053GO:1990723
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RGPD4 RGPD1 RGPD3

1.44e-05101053GO:0044614
GeneOntologyCellularComponentannulate lamellae

RGPD4 RGPD1 RGPD3

4.31e-05141053GO:0005642
GeneOntologyCellularComponentinclusion body

RGPD4 RGPD1 RGPD3 PRDM16 TRIM37

9.10e-05901055GO:0016234
GeneOntologyCellularComponentprotein phosphatase type 2A complex

PPP2R2D PPP2R2B PPP2R2C

9.51e-05181053GO:0000159
GeneOntologyCellularComponentnuclear inclusion body

RGPD4 RGPD1 RGPD3

1.32e-04201053GO:0042405
GeneOntologyCellularComponentA band

ANK2 CMYA5 RYR2 KAT2B

1.35e-04521054GO:0031672
GeneOntologyCellularComponentSUMO ligase complex

RGPD4 RGPD1 RGPD3

1.53e-04211053GO:0106068
GeneOntologyCellularComponentkinetochore

CENPF SEPTIN2 PHF2 KAT2B DYNC1LI1 SKA1

3.07e-041811056GO:0000776
GeneOntologyCellularComponentcondensed chromosome, centromeric region

CENPF SEPTIN2 PHF2 KAT2B DYNC1LI1 SKA1

4.32e-041931056GO:0000779
GeneOntologyCellularComponentnuclear pore

RGPD4 CETN3 RGPD1 RGPD3

1.69e-031011054GO:0005643
MousePhenoabnormal blastocyst formation

RGPD4 RGPD1 RUVBL1 RGPD3 AATF

5.06e-0639915MP:0012128
MousePhenodecreased pituitary gland weight

CSH1 CSH2 CSHL1

1.46e-058913MP:0008938
MousePhenoabsent somatotrophs

CSH1 CSH2 CSHL1

2.18e-059913MP:0008330
MousePhenoabsent lactotrophs

CSH1 CSH2 CSHL1

2.18e-059913MP:0008333
MousePhenodelayed vaginal opening

NSMF CSH1 CSH2 CSHL1

3.05e-0528914MP:0002636
MousePhenoabnormal sex determination

RGPD4 GALNT3 RGPD1 HSPBP1 AK7 SLC4A2 NSMF MAST4 CSH1 CSH2 CSHL1 HHAT RGPD3 PLAT CARD11 TRIM37 PDE11A NOBOX

3.16e-059459118MP:0002210
MousePhenoabnormal timing of vaginal opening

NSMF CSH1 CSH2 CSHL1

4.62e-0531914MP:0020150
MousePhenofailure of blastocyst formation

RGPD4 RGPD1 RGPD3 AATF

4.62e-0531914MP:0012129
MousePhenoaneuploidy

RGPD4 DDX12P RGPD1 SUDS3 RGPD3

4.67e-0561915MP:0004024
MousePhenoincreased circulating ghrelin level

CSH1 CSH2 CSHL1

5.63e-0512913MP:0011612
MousePhenoabnormal pituitary gland weight

CSH1 CSH2 CSHL1

5.63e-0512913MP:0008937
MousePhenoabnormal circulating ghrelin level

CSH1 CSH2 CSHL1

1.15e-0415913MP:0011611
MousePhenoelevated level of mitotic sister chromatid exchange

RGPD4 RGPD1 RGPD3

1.41e-0416913MP:0003701
MousePhenodecreased lactotroph cell number

CSH1 CSH2 CSHL1

1.70e-0417913MP:0008332
MousePhenoabnormal lactotroph morphology

CSH1 CSH2 CSHL1

2.40e-0419913MP:0008323
MousePhenoabnormal chromosome number

RGPD4 DDX12P RGPD1 SUDS3 RGPD3

2.41e-0486915MP:0004023
MousePhenodelayed sexual maturation

NSMF CSH1 CSH2 CSHL1

2.85e-0449914MP:0001938
MousePhenodecreased somatotroph cell number

CSH1 CSH2 CSHL1

3.26e-0421913MP:0008329
MousePhenosmall adenohypophysis

CSH1 CSH2 CSHL1

4.30e-0423913MP:0008321
MousePhenoabnormal somatotroph morphology

CSH1 CSH2 CSHL1

4.89e-0424913MP:0008322
MousePhenoanencephaly

FREM2 TIAM1 TRAPPC10

4.89e-0424913MP:0001890
MousePhenodisproportionate dwarf

CSH1 CSH2 CSHL1 HHAT

5.10e-0457914MP:0002427
MousePhenosmall gonad

RGPD4 GALNT3 RGPD1 HSPBP1 AK7 SLC4A2 NSMF MAST4 HHAT RGPD3 PLAT CARD11 TRIM37 PDE11A NOBOX

5.54e-048859115MP:0001116
DomainPP2A_PR55_CS

PPP2R2D PPP2R2B PPP2R2C

6.68e-0741043IPR018067
DomainPP2A_PR55

PPP2R2D PPP2R2B PPP2R2C

6.68e-0741043IPR000009
DomainPR55_2

PPP2R2D PPP2R2B PPP2R2C

6.68e-0741043PS01025
DomainPR55_1

PPP2R2D PPP2R2B PPP2R2C

6.68e-0741043PS01024
DomainSOMATOTROPIN_2

CSH1 CSH2 CSHL1

3.31e-0661043PS00338
DomainSOMATOTROPIN_1

CSH1 CSH2 CSHL1

3.31e-0661043PS00266
DomainHormone_1

CSH1 CSH2 CSHL1

3.31e-0661043PF00103
DomainSomatotropin

CSH1 CSH2 CSHL1

5.78e-0671043IPR001400
DomainRab_bind

RGPD4 RGPD1 RGPD3

5.78e-0671043PF16704
DomainGCC2_Rab_bind

RGPD4 RGPD1 RGPD3

5.78e-0671043IPR032023
Domain-

RGPD4 RGPD1 RGPD3

1.96e-051010431.10.220.60
DomainGrip

RGPD4 RGPD1 RGPD3

2.68e-05111043SM00755
DomainGRIP

RGPD4 RGPD1 RGPD3

2.68e-05111043PF01465
DomainRan_BP1

RGPD4 RGPD1 RGPD3

3.56e-05121043PF00638
DomainRANBD1

RGPD4 RGPD1 RGPD3

3.56e-05121043PS50196
DomainGRIP_dom

RGPD4 RGPD1 RGPD3

3.56e-05121043IPR000237
DomainGRIP

RGPD4 RGPD1 RGPD3

3.56e-05121043PS50913
DomainRanBD

RGPD4 RGPD1 RGPD3

4.61e-05131043SM00160
DomainRan_bind_dom

RGPD4 RGPD1 RGPD3

4.61e-05131043IPR000156
DomainUbiquitin_3

USP32 USP15

1.83e-0441042PF14836
DomainUb_USP-typ

USP32 USP15

1.83e-0441042IPR028135
DomainEFh

CALU CETN3 SPTA1 RYR2 NECAB1 USP32

2.55e-041581046SM00054
DomainSomatotropin_CS

CSH1 CSHL1

3.04e-0451042IPR018116
Domain-

RGPD4 RGPD1 PLEKHG1 TIAM1 SBF2 RGPD3 PHLDB2 ANKS1A SOS2

3.36e-0439110492.30.29.30
DomainEF-hand_5

CALU NECAB1 USP32

3.53e-04251043PF13202
DomainBromodomain_CS

KAT2B ATAD2B BRD1

3.97e-04261043IPR018359
DomainDH_1

ARHGEF38 PLEKHG1 TIAM1 SOS2

4.20e-04631044PS00741
DomainHECT

HECW1 HECTD3 HUWE1

4.45e-04271043PF00632
DomainHECTc

HECW1 HECTD3 HUWE1

4.45e-04271043SM00119
DomainHECT_dom

HECW1 HECTD3 HUWE1

4.45e-04271043IPR000569
DomainHECT

HECW1 HECTD3 HUWE1

4.45e-04271043PS50237
DomainDUSP

USP32 USP15

4.54e-0461042PF06337
DomainDUSP

USP32 USP15

4.54e-0461042SM00695
DomainRhoGEF

ARHGEF38 PLEKHG1 TIAM1 SOS2

5.62e-04681044SM00325
DomainPH_dom-like

RGPD4 RGPD1 PLEKHG1 TIAM1 SBF2 RGPD3 PHLDB2 ANKS1A SOS2

6.24e-044261049IPR011993
DomainRhoGEF

ARHGEF38 PLEKHG1 TIAM1 SOS2

6.27e-04701044PF00621
DomainDH_2

ARHGEF38 PLEKHG1 TIAM1 SOS2

6.27e-04701044PS50010
DomainDUSP

USP32 USP15

6.33e-0471042PS51283
Domain-

USP32 USP15

6.33e-04710423.30.2230.10
DomainPept_C19_DUSP

USP32 USP15

6.33e-0471042IPR006615
Domain-

ARHGEF38 PLEKHG1 TIAM1 SOS2

6.62e-047110441.20.900.10
DomainDH-domain

ARHGEF38 PLEKHG1 TIAM1 SOS2

6.62e-04711044IPR000219
DomainCalx_beta

FREM3 FREM2

8.41e-0481042SM00237
DomainCalx_beta

FREM3 FREM2

1.08e-0391042IPR003644
DomainCalx-beta

FREM3 FREM2

1.08e-0391042PF03160
DomainBROMODOMAIN_1

KAT2B ATAD2B BRD1

1.14e-03371043PS00633
DomainBromodomain

KAT2B ATAD2B BRD1

1.23e-03381043PF00439
DomainGDS_CDC24_CS

PLEKHG1 TIAM1 SOS2

1.33e-03391043IPR001331
DomainTPR-contain_dom

RGPD4 RGPD1 ZFC3H1 TTC3 RGPD3

1.52e-031501045IPR013026
DomainBROMODOMAIN_2

KAT2B ATAD2B BRD1

1.53e-03411043PS50014
DomainBromodomain

KAT2B ATAD2B BRD1

1.64e-03421043IPR001487
DomainBROMO

KAT2B ATAD2B BRD1

1.64e-03421043SM00297
Domain-

KAT2B ATAD2B BRD1

1.64e-034210431.20.920.10
Domain-

ANK2 CARD6 CARD11 NLRP4

1.81e-039310441.10.533.10
DomainEF_HAND_2

CALU CETN3 SPTA1 RYR2 NECAB1 USP32

1.86e-032311046PS50222
DomainEF_hand_dom

CALU CETN3 SPTA1 RYR2 NECAB1 USP32

1.90e-032321046IPR002048
DomainTPR-like_helical_dom

RGPD4 RGPD1 ZFC3H1 TTC3 RGPD3 TRAPPC10

1.94e-032331046IPR011990
DomainDEATH-like_dom

ANK2 CARD6 CARD11 NLRP4

2.28e-03991044IPR011029
DomainTPR_REGION

RGPD4 RGPD1 ZFC3H1 TTC3 RGPD3

2.30e-031651045PS50293
DomainTPR

RGPD4 RGPD1 ZFC3H1 TTC3 RGPD3

2.30e-031651045PS50005
Domain4_helix_cytokine_core

CSH1 CSH2 CSHL1

2.88e-03511043IPR012351
Domain-

CALU CETN3 SPTA1 RYR2 NECAB1 USP32

3.41e-0326110461.10.238.10
DomainEF-hand-dom_pair

CALU CETN3 SPTA1 RYR2 NECAB1 USP32

5.40e-032871046IPR011992
PathwayREACTOME_AMPLIFICATION_OF_SIGNAL_FROM_THE_KINETOCHORES

RGPD4 CENPF RGPD1 RGPD3 DYNC1LI1 SKA1

1.08e-05100716MM14561
PathwayREACTOME_MITOTIC_SPINDLE_CHECKPOINT

RGPD4 CENPF RGPD1 RGPD3 DYNC1LI1 SKA1

2.65e-05117716MM15387
PathwayREACTOME_PROLACTIN_RECEPTOR_SIGNALING

CSH1 CSH2 CSHL1

3.38e-0513713MM14516
PathwayREACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION

RGPD4 CENPF RGPD1 RGPD3 DYNC1LI1 SKA1

4.60e-05129716MM14894
PathwayREACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING

CSH1 CSH2 CSHL1

6.54e-0516713MM15710
PathwayREACTOME_RHO_GTPASES_ACTIVATE_FORMINS

RGPD4 CENPF RGPD1 RGPD3 DYNC1LI1 SKA1

7.56e-05141716MM15266
PathwayBIOCARTA_RANBP2_PATHWAY

RGPD4 RGPD1 RGPD3

9.46e-0518713MM1549
PathwayBIOCARTA_LONGEVITY_PATHWAY

CSH1 CSH2 CSHL1

1.12e-0419713MM1513
PathwayKEGG_MEDICUS_REFERENCE_PP2A_AKT_SIGNALING_PATHWAY

PPP2R2D PPP2R2B PPP2R2C

1.12e-0419713M47525
PathwayREACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN

CSH1 CSH2 CSHL1

1.31e-0420713MM15070
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

RGPD4 STAM2 DOHH GALNT3 CALU SPTA1 RNF144A RGPD1 ADAMTS5 KAT2B RUVBL1 SUDS3 FDX1 RGPD3 TRAPPC10 DYNC1LI1 USP15 VCPKMT

1.32e-0413897118MM15307
PathwayKEGG_MEDICUS_REFERENCE_CD80_CD86_CTLA4_PP2A_SIGNALING_PATHWAY

PPP2R2D PPP2R2B PPP2R2C

1.76e-0422713M47919
PathwayREACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK

ARHGEF38 TIAM1 AATF SOS2

2.18e-0459714M11215
PathwayBIOCARTA_AKT_PATHWAY

CSH1 CSH2 CSHL1

2.93e-0426713MM1345
PathwayBIOCARTA_TFF_PATHWAY

CSH1 CSH2 CSHL1

4.07e-0429713MM1522
PathwayREACTOME_SEPARATION_OF_SISTER_CHROMATIDS

RGPD4 CENPF RGPD1 RGPD3 DYNC1LI1 SKA1

4.17e-04193716MM14890
PathwayREACTOME_MITOTIC_PROMETAPHASE

RGPD4 CENPF RGPD1 RGPD3 DYNC1LI1 SKA1

5.31e-04202716MM15362
PathwayREACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE

ARHGEF38 TIAM1 AATF SOS2

5.77e-0476714M19832
PathwayBIOCARTA_GH_PATHWAY

CSH1 CSH2 CSHL1

5.99e-0433713MM1404
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

RGPD4 RGPD1 RGPD3

1.06e-0340713MM14945
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

RGPD4 RGPD1 RGPD3

1.14e-0341713MM15200
PathwayREACTOME_MITOTIC_METAPHASE_AND_ANAPHASE

RGPD4 CENPF RGPD1 RGPD3 DYNC1LI1 SKA1

1.14e-03234716MM14898
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

RGPD4 RGPD1 RGPD3

1.22e-0342713MM15039
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

RGPD4 RGPD1 RGPD3

1.31e-0343713MM14609
PathwayREACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING

ARHGEF38 TIAM1 AATF SOS2

1.44e-0397714M9400
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

RGPD4 STAM2 CENPF RGPD1 PLEKHG1 RGPD3 MTR DYNC1LI1 SKA1 SOS2

1.45e-036497110MM15690
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

RGPD4 RGPD1 RGPD3

1.69e-0347713MM14939
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

RGPD4 ANK2 HECW1 CENPF UBR4 RGPD1 HUWE1 TTC3 SEPTIN2 UBE2O NETO1 KIAA1217 RGPD3 PRRC2B PHLDB2 BEGAIN ANKS1A

7.47e-099631081728671696
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ANK2 UBR4 NCKAP5 ZFC3H1 HUWE1 CMYA5 TTC3 SEPTIN2 UBE2O NSMF TIAM1 NECAB1 NETO1 USP32 DGCR8 MBD4 WDR17 TRIM37 SOS2

1.55e-0812851081935914814
Pubmed

The human growth hormone gene locus: structure, evolution, and allelic variations.

CSH1 CSH2 CSHL1

2.91e-08310833030680
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

RGPD4 RGPD1 ELFN2 SEPTIN2 TIAM1 RGPD3 DYNC1LI1 PRRC2B BEGAIN

4.76e-08231108916452087
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

RGPD4 ANK2 HECW1 UBR4 RGPD1 HUWE1 ELFN2 RYR2 YTHDF1 UBE2O RUVBL1 KIAA1217 RGPD3 CNDP2 DYNC1LI1 USP15 BEGAIN

8.49e-0811391081736417873
Pubmed

Developmental control and alternative splicing of the placentally expressed transcripts from the human growth hormone gene cluster.

CSH1 CSH2 CSHL1

1.16e-07410831378436
Pubmed

Central growth hormone action regulates metabolism during pregnancy.

CSH1 CSH2 CSHL1

2.90e-075108331479305
Pubmed

Molecular evolution of growth hormone and receptor in the guinea-pig, a mammal unresponsive to growth hormone.

CSH1 CSH2 CSHL1

2.90e-075108310767558
Pubmed

Heterogeneous growth hormone (GH) gene mutations in familial GH deficiency.

CSH1 CSH2 CSHL1

2.90e-07510838496314
Pubmed

Exploring endocrine GH pattern in mice using rank plot analysis and random blood samples.

CSH1 CSH2 CSHL1

2.90e-075108321045135
Pubmed

Analysis of gender difference of cardiac risk biomarkers using hGH-transgenic mice.

CSH1 CSH2 CSHL1

2.90e-075108316508206
Pubmed

Rescue of pituitary function in a mouse model of isolated growth hormone deficiency type II by RNA interference.

CSH1 CSH2 CSHL1

2.90e-075108318006625
Pubmed

Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia.

CSH1 CSH2 CSHL1

2.90e-075108315616010
Pubmed

Nitric oxide stimulates embryonic somatotroph differentiation and growth hormone mRNA and protein expression through a cyclic guanosine monophosphate-independent mechanism.

CSH1 CSH2 CSHL1

2.90e-075108319019400
Pubmed

The Effects of 20-kDa Human Placental GH in Male and Female GH-deficient Mice: An Improved Human GH?

CSH1 CSH2 CSHL1

2.90e-075108332556100
Pubmed

High frequency of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice created from two different strains of mice.

CSH1 CSH2 CSHL1

2.90e-07510831525063
Pubmed

Obesity and elevated plasma leptin concentration in oMT1A-o growth hormone transgenic mice.

CSH1 CSH2 CSHL1

2.90e-075108311346667
Pubmed

Cardiac contractile function is enhanced in isolated ventricular myocytes from growth hormone transgenic mice.

CSH1 CSH2 CSHL1

2.90e-075108312010633
Pubmed

Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis.

CSH1 CSH2 CSHL1

2.90e-075108317626886
Pubmed

Growth hormone prevents the development of autoimmune diabetes.

CSH1 CSH2 CSHL1

2.90e-075108324218587
Pubmed

Regulation of rapid signal transducer and activator of transcription-5 phosphorylation in the resting cells of the growth plate and in the liver by growth hormone and feeding.

CSH1 CSH2 CSHL1

2.90e-075108319359380
Pubmed

Body composition of inactivated growth hormone (oMt1a-oGH) transgenic mice: generation of an obese phenotype.

CSH1 CSH2 CSHL1

2.90e-07510839546108
Pubmed

Transgene transmission to progeny by oMt1a-oGH transgenic mice.

CSH1 CSH2 CSHL1

2.90e-075108316201410
Pubmed

Growth hormone stimulates the selective trafficking of thymic CD4+CD8- emigrants to peripheral lymphoid organs.

CSH1 CSH2 CSHL1

2.90e-075108315316240
Pubmed

Genes that prolong life: relationships of growth hormone and growth to aging and life span.

CSH1 CSH2 CSHL1

2.90e-075108311487592
Pubmed

Overexpressed growth hormone (GH) synergistically promotes carcinogen-initiated liver tumour growth by promoting cellular proliferation in emerging hepatocellular neoplasms in female and male GH-transgenic mice.

CSH1 CSH2 CSHL1

2.90e-075108311318985
Pubmed

Involvement of insulin-like growth factor-1 in the effect of caloric restriction: regulation of plasma adiponectin and leptin.

CSH1 CSH2 CSHL1

2.90e-075108317301034
Pubmed

Growth hormone action in the developing neural retina: a proteomic analysis.

CSH1 CSH2 CSHL1

2.90e-075108318203262
Pubmed

Identification of the glomerular podocyte as a target for growth hormone action.

CSH1 CSH2 CSHL1

2.90e-075108317272398
Pubmed

Glucose homeostasis and insulin sensitivity in growth hormone-transgenic mice: a cross-sectional analysis.

CSH1 CSH2 CSHL1

2.90e-075108320707609
Pubmed

Assignment of the porcine growth hormone gene to chromosome 12.

CSH1 CSH2 CSHL1

2.90e-07510832249485
Pubmed

Growth hormone stimulates adipogenesis of 3T3-L1 cells through activation of the Stat5A/5B-PPARgamma pathway.

CSH1 CSH2 CSHL1

2.90e-075108317242167
Pubmed

A single injection of double-stranded adeno-associated viral vector expressing GH normalizes growth in GH-deficient mice.

CSH1 CSH2 CSHL1

2.90e-075108318180319
Pubmed

Induction of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice.

CSH1 CSH2 CSHL1

2.90e-07510831874564
Pubmed

Cloning and characterisation of the GH gene from the common dolphin (Delphinus delphis).

CSH1 CSH2 CSHL1

2.90e-075108312225773
Pubmed

Growth Hormone Deficiency and Excess Alter the Gut Microbiome in Adult Male Mice.

CSH1 CSH2 CSHL1

2.90e-075108332100023
Pubmed

The related genes encoding growth hormone and prolactin have been dispersed to chromosomes 10 and 17 in the rat.

CSH1 CSH2 CSHL1

2.90e-07510833780533
Pubmed

High, persistent hepatocellular proliferation and apoptosis precede hepatocarcinogenesis in growth hormone transgenic mice.

CSH1 CSH2 CSHL1

2.90e-075108310395045
Pubmed

Effect of genetic background on growth of mice hemizygous for wild-type or dwarf mutated bovine growth hormone transgenes.

CSH1 CSH2 CSHL1

2.90e-075108324190208
Pubmed

Brief report: short stature caused by a mutant growth hormone.

CSH1 CSH2 CSHL1

2.90e-07510838552145
Pubmed

Promotion of Joint Degeneration and Chondrocyte Metabolic Dysfunction by Excessive Growth Hormone in Mice.

CSH1 CSH2 CSHL1

2.90e-075108336762426
Pubmed

High molecular weight isoforms of growth hormone in cells of the immune system.

CSH1 CSH2 CSHL1

2.90e-075108321741628
Pubmed

Structure of the growth hormone-encoding gene and its promoter in mice.

CSH1 CSH2 CSHL1

2.90e-07510838647448
Pubmed

Thiol-Disulfide Exchange in Human Growth Hormone.

CSH1 CSH2 CSHL1

2.90e-075108326887678
Pubmed

Transgenic mice expressing bovine GH develop arthritic disorder and self-antibodies.

CSH1 CSH2 CSHL1

2.90e-075108310810296
Pubmed

The role of growth hormone in fetal mouse reproductive tract differentiation.

CSH1 CSH2 CSHL1

2.90e-07510838756530
Pubmed

GH Knockout Mice Have Increased Subcutaneous Adipose Tissue With Decreased Fibrosis and Enhanced Insulin Sensitivity.

CSH1 CSH2 CSHL1

2.90e-075108331099824
Pubmed

Somatotropin transgenic mice have reduced jejunal active glucose transport rates.

CSH1 CSH2 CSHL1

2.90e-07510837965203
Pubmed

Hot spots for growth hormone gene deletions in homologous regions outside of Alu repeats.

CSH1 CSH2 CSHL1

2.90e-07510831980158
Pubmed

Vitamin D3 cannot revert desensitization of growth hormone (GH)-induced STAT5-signaling in GH-overexpressing mice non-calcemic tissues.

CSH1 CSH2 CSHL1

2.90e-075108317881271
Pubmed

Neural growth hormone implicated in body weight sex differences.

CSH1 CSH2 CSHL1

2.90e-075108323861378
Pubmed

Growth hormone increases low-density lipoprotein receptor and HMG-CoA reductase mRNA expression in mesangial cells.

CSH1 CSH2 CSHL1

2.90e-075108312759574
Pubmed

Growth hormone production and action in N1E-115 neuroblastoma cells.

CSH1 CSH2 CSHL1

2.90e-075108319301152
Pubmed

Adipocyte insensitivity to insulin in growth hormone-transgenic mice.

CSH1 CSH2 CSHL1

2.90e-075108311350075
Pubmed

Transgenic mice overexpressing growth hormone (GH) have reduced or increased cardiac apoptosis through activation of multiple GH-dependent or -independent cell death pathways.

CSH1 CSH2 CSHL1

2.90e-075108318617616
Pubmed

Adipocytokines and the regulation of lipid metabolism in growth hormone transgenic and calorie-restricted mice.

CSH1 CSH2 CSHL1

2.90e-075108317347312
Pubmed

Growth hormone and fertility in oMt1a-oGH transgenic mice.

CSH1 CSH2 CSHL1

2.90e-075108311570960
Pubmed

Promoter shuffling has occurred during the evolution of the vertebrate growth hormone gene.

CSH1 CSH2 CSHL1

2.90e-075108310974531
Pubmed

Pleiotropic effects of growth hormone signaling in aging.

CSH1 CSH2 CSHL1

2.90e-075108321852148
Pubmed

Body composition, bone mass and microstructural analysis in GH-transgenic mice reveals that skeletal changes are specific to bone compartment and gender.

CSH1 CSH2 CSHL1

2.90e-075108312175649
Pubmed

Transgenic mice reveal novel activities of growth hormone in wound repair, angiogenesis, and myofibroblast differentiation.

CSH1 CSH2 CSHL1

2.90e-075108315070902
Pubmed

Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormone.

CSH1 CSH2 CSHL1

2.90e-075108323428905
Pubmed

A novel missense mutation in the mouse growth hormone gene causes semidominant dwarfism, hyperghrelinemia, and obesity.

CSH1 CSH2 CSHL1

2.90e-075108314726450
Pubmed

UV photodegradation of murine growth hormone: chemical analysis and immunogenicity consequences.

CSH1 CSH2 CSHL1

2.90e-075108324758742
Pubmed

Consequences of overexpression of growth hormone in transgenic mice on liver cytochrome P450 enzymes.

CSH1 CSH2 CSHL1

2.90e-075108310076541
Pubmed

Overgrowth of skin in growth hormone transgenic mice depends on the presence of male gonads.

CSH1 CSH2 CSHL1

2.90e-075108310594738
Pubmed

Hypoxia and cytoplasmic alkalinization upregulate growth hormone expression in lymphocytes.

CSH1 CSH2 CSHL1

2.90e-075108323639351
Pubmed

Pituitary growth hormone network responses are sexually dimorphic and regulated by gonadal steroids in adulthood.

CSH1 CSH2 CSHL1

2.90e-075108321098290
Pubmed

Cardiac expression of adenine nucleotide translocase-1 in transgenic mice overexpressing bovine GH.

CSH1 CSH2 CSHL1

2.90e-075108317761891
Pubmed

Age-related changes in body composition of bovine growth hormone transgenic mice.

CSH1 CSH2 CSHL1

2.90e-075108318948397
Pubmed

The human growth hormone locus: nucleotide sequence, biology, and evolution.

CSH1 CSH2 CSHL1

5.78e-07610832744760
Pubmed

Growth hormone, acting in part through the insulin-like growth factor axis, rescues developmental, but not metabolic, activity in the mammary gland of mice expressing a single allele of the prolactin receptor.

CSH1 CSH2 CSHL1

5.78e-076108312399427
Pubmed

Transgenic mice over-expressing galanin exhibit pituitary adenomas and increased secretion of galanin, prolactin and growth hormone.

CSH1 CSH2 CSHL1

5.78e-076108314596666
Pubmed

GH modulates hepatic epidermal growth factor signaling in the mouse.

CSH1 CSH2 CSHL1

5.78e-076108320032199
Pubmed

Growth inhibition in giant growth hormone transgenic mice by overexpression of insulin-like growth factor-binding protein-2.

CSH1 CSH2 CSHL1

5.78e-076108311316754
Pubmed

The use of transgenic mice to analyze the role of accessory factor two in the regulation of phosphoenolpyruvate carboxykinase (GTP) gene transcription during diabetes.

CSH1 CSH2 CSHL1

5.78e-076108311309401
Pubmed

The rise in growth hormone during starvation does not serve to maintain glucose levels or lean mass but is required for appropriate adipose tissue response in female mice.

CSH1 CSH2 CSHL1

5.78e-076108323150490
Pubmed

Nucleotide sequence of mouse prolactin and growth hormone mRNAs and expression of these mRNAs during pregnancy.

CSH1 CSH2 CSHL1

5.78e-07610832991252
Pubmed

Genetic dissection of IGF1-dependent and -independent effects of permanent GH excess on postnatal growth and organ pathology of mice.

CSH1 CSH2 CSHL1

5.78e-076108325017732
Pubmed

Third party data gene data set of eutherian growth hormone genes.

CSH1 CSH2 CSHL1

5.78e-076108326697363
Pubmed

Role of growth hormone in the genetic change of mice divergently selected for body weight and fatness.

CSH1 CSH2 CSHL1

5.78e-076108310689811
Pubmed

Effects of long-term treatment with growth hormone-releasing peptide-2 in the GHRH knockout mouse.

CSH1 CSH2 CSHL1

5.78e-076108315985453
Pubmed

Phosphorylation of sterol regulatory element-binding protein (SREBP)-1a links growth hormone action to lipid metabolism in hepatocytes.

CSH1 CSH2 CSHL1

5.78e-076108320863500
Pubmed

An early reduction in GH peak amplitude in preproghrelin-deficient male mice has a minor impact on linear growth.

CSH1 CSH2 CSHL1

5.78e-076108324949662
Pubmed

Growth Hormone Pulses and Liver Gene Expression Are Differentially Regulated by the Circadian Clock Gene Bmal1.

CSH1 CSH2 CSHL1

5.78e-076108333539533
Pubmed

Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice.

CSH1 CSH2 CSHL1

5.78e-076108320231469
Pubmed

Growth hormone resistance: clinical states and animal models.

CSH1 CSH2 CSHL1

5.78e-076108310556764
Pubmed

Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling.

CSH1 CSH2 CSHL1

5.78e-076108312208853
Pubmed

Involvement of growth hormone as a regulating factor in sex differences of mouse hepatic aldehyde oxidase.

CSH1 CSH2 CSHL1

5.78e-07610839175714
Pubmed

Disruption of growth hormone signaling retards early stages of prostate carcinogenesis in the C3(1)/T antigen mouse.

CSH1 CSH2 CSHL1

5.78e-076108316141391
Pubmed

Sex differences in thrombosis in mice are mediated by sex-specific growth hormone secretion patterns.

CSH1 CSH2 CSHL1

5.78e-076108318618017
Pubmed

Transcript abundance in mouse pituitaries with altered growth hormone expression quantified by reverse transcriptase polymerase chain reaction implicates transcription factor Zn-16 in gene regulation in vivo.

CSH1 CSH2 CSHL1

5.78e-076108312166626
Pubmed

Growth hormone expression in murine bone marrow cells is independent of the pituitary transcription factor Pit-1.

CSH1 CSH2 CSHL1

5.78e-07610839275086
Pubmed

Disruption of JAK2 in adipocytes impairs lipolysis and improves fatty liver in mice with elevated GH.

CSH1 CSH2 CSHL1

5.78e-076108323782652
Pubmed

Growth hormone is a positive regulator of adiponectin receptor 2 in 3T3-L1 adipocytes.

CSH1 CSH2 CSHL1

5.78e-076108314759511
Pubmed

Age related changes in gene expression within the cochlea of C57BL/6J mice.

CSH1 CSH2 CSHL1

5.78e-076108323010755
Pubmed

Acylated ghrelin is not required for the surge in pituitary growth hormone observed in pregnant mice.

CSH1 CSH2 CSHL1

5.78e-076108325645493
Pubmed

Administration of human insulin-like growth factor-binding protein-1 increases circulating levels of growth hormone in mice.

CSH1 CSH2 CSHL1

5.78e-076108315166120
Pubmed

Osteocalcin induces growth hormone/insulin-like growth factor-1 system by promoting testosterone synthesis in male mice.

CSH1 CSH2 CSHL1

5.78e-076108324691732
Pubmed

Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice.

CSH1 CSH2 CSHL1

5.78e-076108321725989
InteractionCSHL1 interactions

UBR4 CSH1 CSH2 CSHL1

2.60e-0871074int:CSHL1
InteractionIER5 interactions

PPP2R2D PPP2R2B PPP2R2C SKA1

5.18e-07131074int:IER5
Cytoband17q24.2

CSH1 CSH2 CSHL1

4.91e-0530108317q24.2
CytobandEnsembl 112 genes in cytogenetic band chr17q23

CSH1 CSH2 CSHL1 USP32

1.93e-041201084chr17q23
Cytoband1q41

CENPF RRP15 C1orf115

5.20e-046610831q41
GeneFamilyGrowth hormone family

CSH1 CSH2 CSHL1

1.20e-0667231175
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R2D PPP2R2B PPP2R2C

2.66e-0515723696
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF38 PLEKHG1 TIAM1 SOS2

1.38e-0466724722
GeneFamilyEF-hand domain containing

CALU CETN3 SPTA1 RYR2 NECAB1 USP32

2.37e-04219726863
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RGPD4 RGPD1 TTC3 RGPD3

1.15e-03115724769
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHG1 TIAM1 SBF2 PHLDB2 SOS2

1.38e-03206725682
CoexpressionNAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_7DY_NEGATIVE

RGPD4 KLHL24 GALNT3 RGPD1 ACBD6 ATAD2B RGPD3 TRAPPC10 BRD1 FHIT MBD4 VCPKMT

6.18e-0747410812M40991
CoexpressionTABULA_MURIS_SENIS_TRACHEA_GRANULOCYTE_AGEING

RGPD4 RGPD1 ACBD6 SUDS3 RGPD3

9.19e-07431085MM3857
CoexpressionGSE30083_SP2_VS_SP3_THYMOCYTE_UP

ANK2 CMYA5 AK7 MAST4 HHAT PRDM16 NLRP4 PDE11A

1.76e-061991088M5031
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

KLHL24 ANK2 NCKAP5 CMYA5 RYR2 MAST4 FHIT PRDM16

2.14e-081901088fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

KLHL24 ANK2 CMYA5 RYR2 MAST4 FHIT PRDM16

4.03e-0718910875e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

ANK2 NCKAP5 CMYA5 RYR2 MAST4 KIAA1217 PHLDB2

4.03e-0718910870a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

KLHL24 ANK2 CMYA5 RYR2 MAST4 FHIT PRDM16

4.17e-071901087de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

KLHL24 ANK2 NCKAP5 CMYA5 RYR2 MAST4 FHIT

4.48e-071921087ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

ANK2 NCKAP5 CMYA5 RYR2 MAST4 FHIT PRDM16

4.64e-071931087dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANK2 ARHGEF38 FREM2 MAST4 MTR FHIT PRDM16

5.14e-071961087eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellcontrol-Epithelial-Ionocyte|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ANK2 NCKAP5 C1orf115 NSMF PHLDB2 PDE11A

3.12e-0616510865cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCellcontrol-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ANK2 NCKAP5 C1orf115 NSMF PHLDB2 PDE11A

3.46e-061681086327b02f19f4a8607c033203824fdc60a1254331f
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

TIAM1 SUDS3 SBF2 TRAPPC10 DNASE1L3

3.54e-069510853d6b97576ce4e7a3e495cbc7246ea8c0b2a386f7
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

KLHL24 ANK2 NCKAP5 CMYA5 RYR2 PRDM16

6.81e-0618910869c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

ANK2 NCKAP5 CMYA5 RYR2 MAST4 PHLDB2

7.01e-06190108693c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

KLHL24 ANK2 CMYA5 RYR2 MAST4 FHIT

7.23e-06191108625f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARHGEF38 NCKAP5 PLEKHG1 MAST4 KIAA1217 PRDM16

7.23e-06191108623776c7302cead3881b39127398f3b3e0d27885e
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARHGEF38 FREM2 MAST4 NECAB1 KIAA1217 PRDM16

7.23e-061911086e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GALNT3 ARHGEF38 PLEKHG1 FREM2 SKA1 PRDM16

7.45e-06192108625378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

ARHGEF38 NCKAP5 PLEKHG1 MAST4 KIAA1217 PRDM16

7.67e-0619310862bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

ANK2 NCKAP5 CMYA5 RYR2 MAST4 FHIT

7.90e-061941086c3535f7cc0076653c72db582047cff053c322397
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

ANK2 NCKAP5 CMYA5 RYR2 MAST4 FHIT

8.14e-06195108675fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARHGEF38 NCKAP5 PLEKHG1 MAST4 KIAA1217 PRDM16

8.14e-061951086dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANK2 PPP2R2B MAST4 MTR FHIT PRDM16

8.38e-061961086c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGEF38 FREM2 MAST4 KIAA1217 FHIT PRDM16

9.13e-0619910865f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGEF38 FREM2 MAST4 KIAA1217 FHIT PRDM16

9.13e-0619910865cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

ANK2 RYR2 PPP2R2C C1orf115 MAST4 NECAB1

9.40e-06200108661d7dd0a78942b069c3f5e75044368dc00e6e8e6
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

ANK2 RYR2 PPP2R2C C1orf115 MAST4 NECAB1

9.40e-0620010865c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1-Excitatory_Neuron.Slc17a7.Cbln1-Gpr88_(Medial_entorrhinal_cortex)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

ADAM7 ARHGEF38 DNASE1L3 NOBOX

1.05e-05561084a310f50724ada8da92257c54b18d9214d7415010
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1-Excitatory_Neuron.Slc17a7.Cbln1-Gpr88_(Medial_entorrhinal_cortex)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ADAM7 ARHGEF38 DNASE1L3 NOBOX

1.05e-055610844740900fffc892200f3e2480328eb43cb6d19f20
ToppCelldroplet-Heart-nan-3m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTA1 UBE2O CARD11 PROSER2 DNASE1L3

2.34e-051401085ab90f6f30d89761687f8836e3d327d143ce49ed4
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HECW1 ADAM7 FREM2 PPP2R2B PDE11A

4.70e-051621085bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

KLHL24 ARHGEF38 MAST4 KIAA1217 PRDM16

4.84e-051631085e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCellNS-control-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ANK2 NCKAP5 C1orf115 NSMF PDE11A

5.28e-0516610856d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCell343B-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

GALNT3 ABCA6 HHAT CARD11 DNASE1L3

5.75e-051691085632aa3ab39ec87bafcefec6cddf71129a054d3b0
ToppCellEndothelial-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

PTCHD3 ADAMTS5 PLEKHG1 PPP2R2B PLAT

6.42e-051731085a81992965137195d20fc498f750975303961a828
ToppCellnucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-pDC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KAT2B HHAT ANKRD11 CARD11 DNASE1L3

6.78e-05175108537c2d4e0b6e9a3171931797ce9a54f3347288e57
ToppCellNS-moderate-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ANK2 NCKAP5 C1orf115 PHLDB2 PDE11A

6.78e-051751085a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGEF38 FREM2 MAST4 KIAA1217 PRDM16

7.54e-051791085815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCellNS-moderate-d_16-33-Epithelial-Ionocyte|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ANK2 NCKAP5 C1orf115 NECAB1 PDE11A

7.74e-0518010858af8b4af2dc72223ac71fc027e0d4280c5dd81f8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ANK2 ARHGEF38 MAST4 FHIT PRDM16

7.74e-0518010859e09b3dfe344b5d50520711513d389865d73a861
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

HHAT FDX1 CARD6 SKA1 PDE11A

7.74e-05180108581d60f0fa9e3b5bfcec85139a0a49e9130145f0e
ToppCellNS-critical-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ANK2 NCKAP5 C1orf115 NECAB1 PDE11A

7.95e-051811085cfc3ed541d93158ce26641ea30b7573d93600a11
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AK7 PPP2R2C C1orf115 PLAT PHLDB2

8.37e-0518310856f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

ANK2 CMYA5 RYR2 MAST4 FHIT

8.59e-051841085ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARHGEF38 PLEKHG1 FREM2 MAST4 PRDM16

8.59e-051841085102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

ARHGEF38 PLEKHG1 MAST4 KIAA1217 PRDM16

8.81e-05185108598b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CENPF SPTA1 UBE2O USP32 USP15

8.81e-051851085e8f7da9641b6cf1db1093b4f301ce828fd3a529c
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

ANK2 CMYA5 RYR2 MAST4 FHIT

8.81e-0518510856baccb26f999145e51b91d94315bf8d4655bef31
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGEF38 FREM2 MAST4 KIAA1217 PRDM16

9.04e-0518610852ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

RNF144A PLEKHG1 SBF2 MTR FHIT

9.27e-051871085f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCellmoderate-Epithelial-Ionocyte|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ANK2 NCKAP5 C1orf115 NECAB1 PDE11A

9.27e-0518710853e3fe2d5712a0ac477cddefe56705d4b8d8f7eac
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-Cycling_Dendritic|lymph-node_spleen / Manually curated celltypes from each tissue

CENPF NCKAP5 SHCBP1 SKA1 DNASE1L3

9.50e-051881085723348a1836a074e068320cb736ce6a953e0038f
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CFAP47 ARHGEF38 PLEKHG1 FREM2 PRDM16

9.74e-0518910857659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GALNT3 ARHGEF38 PLEKHG1 FREM2 PRDM16

9.74e-051891085c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FREM2 MAST4 NECAB1 KIAA1217 PRDM16

9.99e-0519010858aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

ANK2 ADAMTS5 ABCA6 PLAT PHLDB2

9.99e-0519010857dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GALNT3 ARHGEF38 PLEKHG1 FREM2 PRDM16

9.99e-051901085c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF38 PPP2R2B MAST4 FHIT PRDM16

9.99e-051901085cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCellCOPD-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

RGPD1 KAT2B MAST4 TIAM1 USP15

1.02e-0419110853ae18bc4e3dff49b5d5958da8ebc3f747274b69c
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CFAP47 ARHGEF38 PLEKHG1 FREM2 PRDM16

1.02e-04191108560ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

ANK2 NCKAP5 CMYA5 RYR2 MAST4

1.02e-0419110855d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellCOVID-19-kidney-Proliferating_T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

CENPF SPTA1 SHCBP1 CARD11 SKA1

1.02e-041911085bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

RNF144A PLEKHG1 KIAA1217 PLAT DNASE1L3

1.02e-0419110852f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

ARHGEF38 FREM2 MAST4 KIAA1217 PRDM16

1.05e-041921085499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ANK2 ARHGEF38 PLEKHG1 FREM2 PRDM16

1.05e-041921085b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGEF38 FREM2 MAST4 NECAB1 KIAA1217

1.05e-041921085fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell|Adult / Lineage, Cell type, age group and donor

ANK2 ADAMTS5 ABCA6 PLAT PHLDB2

1.05e-041921085d21f0f577156f17c899b08871046a26b88aea011
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

NCKAP5 MAST4 SBF2 ANKRD11 FHIT

1.05e-041921085e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

HUWE1 SBF2 USP32 TRAPPC10 AQR

1.07e-041931085abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARHGEF38 FREM2 MAST4 KIAA1217 PRDM16

1.07e-041931085a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-OPC_related|GW19 / Sample Type, Dataset, Time_group, and Cell type.

ARHGEF38 NCKAP5 NETO1 KIAA1217 PROSER2

1.07e-04193108580ae4d11e373e54ead919294786e0a8cbd11ea8a
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-OPC_related-OPC|GW19 / Sample Type, Dataset, Time_group, and Cell type.

ARHGEF38 NCKAP5 NETO1 KIAA1217 PROSER2

1.07e-0419310855c3b4cc1ca8439ac59ba00253903b9774dc048f8
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CENPF FREM2 SHCBP1 SKA1 PRDM16

1.10e-041941085c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ARHGEF38 NCKAP5 FREM2 MAST4 PRDM16

1.10e-04194108553f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

ANK2 NCKAP5 CMYA5 RYR2 MAST4

1.10e-04194108589812fb164065041357bb37a3c2d87028ec3de4e
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CFAP47 ARHGEF38 PLEKHG1 FREM2 PRDM16

1.10e-0419410856b286992d4bb56013c0ea5a7601d3476d806175a
ToppCellCOVID-19-kidney-Glomerular_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

RNF144A PLEKHG1 KIAA1217 PLAT DNASE1L3

1.10e-041941085660535b492445063d965095a50e1e299ce04c50a
ToppCellPCW_07-8.5-Epithelial|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GALNT3 ARHGEF38 PLEKHG1 FREM2 PRDM16

1.10e-041941085f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CFAP47 ARHGEF38 PLEKHG1 FREM2 PRDM16

1.10e-041941085f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

ANK2 NCKAP5 CMYA5 RYR2 FHIT

1.13e-041951085f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellCOVID-19-kidney-Proliferating_T_cell|kidney / Disease (COVID-19 only), tissue and cell type

CENPF SPTA1 SHCBP1 CARD11 SKA1

1.13e-0419510857e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF38 MAST4 MTR FHIT PRDM16

1.13e-0419510856477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellBronchus_Control_(B.)-Epithelial-TX-AT1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

ANK2 RNF144A C1orf115 HHAT PDE11A

1.18e-041971085f7ef62d78336812573148f8bfce401877ec4e29c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RNF144A PLEKHG1 PLAT DNASE1L3 ANKS1A

1.21e-0419810851378c6d4ceb84b42fdd6556be3296df7a8059e6e
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

ANK2 RYR2 HHAT SKA1 BEGAIN

1.21e-0419810850c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCellFetal_29-31_weeks-Epithelial-club_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KLHL24 ARHGEF38 MAST4 KIAA1217 PRDM16

1.21e-0419810855fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGEF38 FREM2 MAST4 NECAB1 PRDM16

1.24e-041991085725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCelldistal-3-mesenchymal-Adventitial_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ANK2 ADAMTS5 ABCA6 MKRN9P PLAT

1.24e-041991085547a7c30abc730af2670aee00c7a6af60426c9ac
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANK2 RNF144A ELFN2 ABCA6 PHLDB2

1.24e-0419910853835452e4848d7f7dd8651c17b746b271ef39688
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANK2 RNF144A ELFN2 ABCA6 PHLDB2

1.24e-0419910859c2db0bb94cba71a3cc1827844da090e213e0258
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

RNF144A NCKAP5 SEPTIN2 MAST4 KIAA1217

1.27e-042001085f15fffefe372005c33e31845982e2d2714ac26af
ToppCellLPS-IL1RA-Unknown-Endothelial-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CENPF SHCBP1 PLAT WDR17

2.43e-0412510842938a1d62afe1e0a3abba5eb92f07b886cc0accd
Diseaseisolated growth hormone deficiency type II (implicated_via_orthology)

CSH1 CSH2 CSHL1

4.36e-0751053DOID:0060872 (implicated_via_orthology)
Diseaseisolated growth hormone deficiency (implicated_via_orthology)

CSH1 CSH2 CSHL1

1.52e-0671053DOID:0060870 (implicated_via_orthology)
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

PPP2R2D PPP2R2B PPP2R2C

9.41e-06121053DOID:1441 (implicated_via_orthology)
Diseasecongenital hypothyroidism (biomarker_via_orthology)

CSH1 CSH2 CSHL1

1.55e-05141053DOID:0050328 (biomarker_via_orthology)
Diseaseosteoporosis (biomarker_via_orthology)

CSH1 CSH2 CSHL1

6.42e-05221053DOID:11476 (biomarker_via_orthology)
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

CSH1 CSH2 CSHL1 MTR PLAT

1.85e-041471055DOID:9352 (biomarker_via_orthology)
DiseaseS-7-hydroxywarfarin to S-warfarin ratio measurement

PPP2R2B TIAM1 FHIT AQR

2.04e-04811054EFO_0803334
Diseasesyndromic X-linked intellectual disability (implicated_via_orthology)

HUWE1 PHF2

3.46e-0481052DOID:0060309 (implicated_via_orthology)
Diseasetype 1 diabetes mellitus (implicated_via_orthology)

CSH1 CSH2 CSHL1

3.65e-04391053DOID:9744 (implicated_via_orthology)
Diseaseheel bone mineral density, urate measurement

SPTA1 GPR149 BRD1 PHLDB2 PDE11A

4.96e-041821055EFO_0004531, EFO_0009270
DiseaseVENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1 (disorder)

ANK2 RYR2

5.54e-04101052C1631597
DiseaseR-6-hydroxywarfarin measurement

NETO1 CARD6 MTR AQR

7.48e-041141054EFO_0803327
Diseasealcohol and nicotine codependence

RGPD1 PLEKHG1

9.54e-04131052EFO_0004776
Diseaserenal sinus adipose tissue measurement

TIAM1 FDX1

9.54e-04131052EFO_0004864
Diseaseposterior thigh muscle volume

CSH1 CSHL1

1.28e-03151052EFO_0020931
DiseaseFEV/FEC ratio

ARHGEF38 ADAMTS5 SEPTIN2 PHF2 FREM2 NETO1 HHAT FDX1 SBF2 ANKRD11 PRDM16 PHLDB2

1.41e-03122810512EFO_0004713
DiseaseHeadache

GPR149 HHAT PRDM16

1.56e-03641053HP_0002315
Diseasecaudal anterior cingulate cortex volume measurement

HECW1 FHIT

1.65e-03171052EFO_0010289
Diseaseobesity

CMYA5 KIAA1217 CARD11 FHIT PRDM16

1.73e-032411055EFO_0001073
DiseaseAntihypertensive use measurement

PLEKHG1 KAT2B SBF2 PRDM16 PHLDB2

2.62e-032651055EFO_0009927
Diseasemean platelet volume

PCDHGA2 SPTA1 MAST4 ATAD2B ANKRD11 PROSER2 BRD1 TASOR PRDM16 ANKS1A

3.48e-03102010510EFO_0004584
Diseasecoronary artery disease

PHF2 PLEKHG1 MAST4 GPR149 KIAA1217 HHAT FDX1 SEC63 PRDM16 NLRP4 ANKS1A

3.52e-03119410511EFO_0001645

Protein segments in the cluster

PeptideGeneStartEntry
HLEEEEYLEKAGYLE

ERICH6B

91

Q5W0A0
YLEEEEYLGKEEHLE

ERICH6B

121

Q5W0A0
EYLGKEEHLEEEEYL

ERICH6B

126

Q5W0A0
HEAAYLADEREDLLT

SLC4A2

586

P04920
HEPEFDYLKSLEIEE

PPP2R2B

76

Q00005
HEPEFDYLKSLEIEE

PPP2R2C

76

Q9Y2T4
YKNLHEFEEDFDLII

BRD1

621

O95696
EEALHEYREDSNDKI

ANKRD11

1286

Q6UB99
EEFLEAHSTDEFKDV

CCDC7

246

Q96M83
EKLETEFDSTRHYLE

BEGAIN

26

Q9BUH8
DHIYEKLDAITDEEN

FDX1

121

P10109
THDDDILKTYEEELL

ADAM7

46

Q9H2U9
HDEKYVELFIVADDT

ADAM7

196

Q9H2U9
EEHYDAAILFTREDL

ADAMTS5

356

Q9UNA0
HDEAHSILESYEKEE

ARHGEF38

191

Q9NXL2
IEKEIDAEHPSDDYF

ABCA6

451

Q8N139
TSDSDDYHLLKDLEE

CSHL1

136

Q14406
HEPEFDYLKSLEIEE

PPP2R2D

86

Q66LE6
DYDHDAFLGAEEAKT

CALU

46

O43852
HGEEELETEKDFSRY

AQR

881

O60306
DEEEEDHIDKKYFPL

ANKS1A

416

Q92625
HEETIREEDKNIFDY

ACBD6

151

Q9BR61
EEKPKDSEELEYFNH

DGCR8

586

Q8WYQ5
DSEELEYFNHISIED

DGCR8

591

Q8WYQ5
EAAAILEHLEYADEA

C1orf115

31

Q9H7X2
LEHLEYADEAEAAAE

C1orf115

36

Q9H7X2
AFDDDSALLKHELAY

DOHH

46

Q9BU89
DFADVADDFENYHKL

NETO1

406

Q8TDF5
DLDYEDATFHEIDIE

PCDHGA2

306

Q9Y5H1
ELEKIFQEDHYPDSD

NOBOX

286

O60393
KEHFCDYTEDELNEI

ANK2

1106

Q01484
FDFEKIPLEKHDEEY

VCPKMT

196

Q9H867
FLDDVFEVKLHDNYE

KIAA0100

881

Q14667
HTYTFIDKVDLTDEE

MAGEB2

176

O15479
LDVEYLFTCVHKEED

KAT2B

166

Q92831
SDYERLEHGTLFDDK

SBF2

1516

Q86WG5
DLSDLEYLDEEFHQS

HECW1

1376

Q76N89
FADYENHTEDRKLLE

ATAD2B

1166

Q9ULI0
IDDSLYEEEETFHVL

FREM2

1966

Q5SZK8
SVLEKEHDYRDEHFD

DYNC1LI1

251

Q9Y6G9
TSDSDDYHLLKDLEE

CSH2

131

P0DML3
LAIDDIHFDDFSLDV

PDE11A

606

Q9HCR9
LYDHEHATFEDILEE

NSMF

376

Q6X4W1
LYFEEEVKQEECDHL

NLRP4

121

Q96MN2
IARSDDELLDDFFHD

HUWE1

2616

Q7Z6Z7
ESLDDDFLLIHYDKG

RNF144A

216

P50876
KIAHEDYYDDDENSI

GPR149

411

Q86SP6
YKVSREHEEELDQEF

HHAT

26

Q5VTY9
EHVGFSLDVDEIEKY

NBPF3

526

Q9H094
EYEEDAHVTFAILDA

RGPD3

646

A6NKT7
DSIYEELQKHDKEDF

FHIT

111

P49789
HEEFLELDKDELIDY

KLHL24

201

Q6TFL4
EKEHLDLETSEFFRD

CARD6

136

Q9BX69
YKLTEEEALDVSDHF

DNASE1L3

261

Q13609
DLSEKLEYFSCDHQE

CENPF

1841

P49454
ILVDDASVDEYLHDK

GALNT3

221

Q14435
ASVDEYLHDKLDEYV

GALNT3

226

Q14435
ALEHEYDLVKLDESF

CMYA5

3101

Q8N3K9
DEDDLEEEHITKIYH

DDX12P

236

Q92771
LFDTDKDEAIDYHEL

CETN3

36

O15182
DSEHNEKYEDTFLES

MBD4

341

O95243
LYEGHIEKDAREFLD

MAST4

726

O15021
TSDSDDYHLLKDLEE

CSH1

131

P0DML2
TEEHYFEDKLIEDLA

RYR2

3631

Q92736
EYHPDKDEDTFDRLL

CFAP47

106

Q6ZTR5
FDALDLDDDSHERYS

CARD11

596

Q9BXL7
FLYLPKDEEEDLEEH

PTCHD3

156

Q3KNS1
DDDGFIEDKYIDIHE

LRRC19

351

Q9H756
EYEEDAHITFAILDA

RGPD1

636

P0DJD0
DESDLFHEELEDFYD

MKRN9P

16

Q6NVV0
IVYEHDDSETKEDSF

FREM3

1266

P0C091
HEEYQEELEFCEKLL

HSPBP1

331

Q9NZL4
EYEEDAHVTFAILDA

RGPD4

646

Q7Z3J3
YASSIDDILEDEEHY

SNX4

286

O95219
DDILEDEEHYADQLK

SNX4

291

O95219
HELSDGDLDLDLVYE

TRIM37

511

O94972
EHHFYDFERDLELLE

SOS2

696

Q07890
EEQDHLDACFKDSDY

PHF2

861

O75151
SLEEDYKDIEHLKEN

SKA1

76

Q96BD8
KTFVYDLDSHVDADD

NCKAP5

466

O14513
LDDESLKYLTHEEKD

PROSER2

46

Q86WR7
NHALLDEKEDSYFSE

PRDM16

1061

Q9HAZ2
EEYEDIRQDHYESLK

MTR

911

Q99707
EFFHEDVRKSDVEYE

KIAA1217

1181

Q5T5P2
SDDIYKEDFNELLHK

WDR17

931

Q8IZU2
KEGILIKDFLDEHYD

SHCBP1

511

Q8NEM2
DADLLDVESKHFEDL

PHLDB2

711

Q86SQ0
TDDAYEELRQKHEYE

TASOR

801

Q9UK61
KDLDEEIFDDDDFYH

AATF

451

Q9NY61
EIFDDDDFYHQLLRE

AATF

456

Q9NY61
LKEEDGEEIVTYDHL

CHURC1

46

Q8WUH1
EEEHKLYDDIDFDIE

CNDP2

271

Q96KP4
DHFSDLVKTYSLEEE

C10orf120

306

Q5SQS8
EEFKEDIDYRHFKDE

TCEAL7

46

Q9BRU2
KEFDDDTYDNDIALL

PLAT

396

P00750
RELFALTDAESEEHY

TIAM1

1201

Q13009
HLYNIESEIEESDYD

UBE2O

706

Q9C0C9
YFDENAAEDFEKHES

USP15

761

Q9Y4E8
DHLRQDVEEFEALYD

TTC3

1071

P53804
HEEVDYSEKLKFSDD

PRRC2B

376

Q5JSZ5
HTLLHFLEDEKYEEV

SEC63

421

Q9UGP8
YDFEAVEDNELTFKH

STAM2

211

O75886
SEKDHFYSDDDAIEA

RRP15

51

Q9Y3B9
FAESLIADEHYAKEE

SPTA1

1456

P02549
EKEHVEEISELFYDA

RUVBL1

426

Q9Y265
YHLPDAESDEDEDFK

SEPTIN2

211

Q15019
DIDHVYDNISYEDLK

PLEKHG1

656

Q9ULL1
EALSSVEAFEKHYLD

TRAPPC10

446

P48553
DASETDLAKHDEEDY

SUDS3

51

Q9H7L9
KYDEDHSGDDKVFLD

UBR4

4646

Q5T4S7
LHLESTFEEKDYVCE

ZFC3H1

1441

O60293
DDEDHKLEYLKIQDE

USP32

681

Q8NFA0
SIFDDFAHYEKRQEE

YTHDF1

531

Q9BYJ9
VQFAKDEDLHDILDY

ELFN2

796

Q5R3F8
DLIHFLYDHLGKEDE

HECTD3

221

Q5T447
DDETVFNYFDELEIH

AK7

566

Q96M32
IEEDLEEFQLALKHY

NECAB1

261

Q8N987