Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF726P1 ZNF84 ZNF225 PPARA NR3C1 FOXA1 FOXA2 HNF4G CREM ZFY

4.85e-0512443610GO:0000978
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

ZNF225 PPARA NR3C1 FOXA1 FOXA2 HNF4G ZFY

5.41e-05560367GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

ZNF225 PPARA NR3C1 FOXA1 FOXA2 HNF4G ZFY

5.79e-05566367GO:0001216
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF726P1 ZNF84 ZNF225 PPARA NR3C1 FOXA1 FOXA2 HNF4G CREM ZFY

5.82e-0512713610GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF726P1 ZNF84 ZNF225 PPARA NR3C1 FOXA1 FOXA2 HNF4G CREM ZFY

1.40e-0414123610GO:0000981
GeneOntologyMolecularFunctionnuclear receptor activity

PPARA NR3C1 HNF4G

1.72e-0460363GO:0004879
GeneOntologyMolecularFunctionligand-activated transcription factor activity

PPARA NR3C1 HNF4G

1.80e-0461363GO:0098531
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF726P1 ZNF84 ZNF225 PPARA NR3C1 FOXA1 FOXA2 HNF4G CREM ZFY

1.84e-0414593610GO:0000977
GeneOntologyMolecularFunctiontranscription factor binding

LMO3 PPARA NR3C1 FOXA1 FOXA2 LMO1 CREM

3.38e-04753367GO:0008134
GeneOntologyMolecularFunctionzinc ion binding

DUSP12 ZC3HC1 ZNF84 PPARA NR3C1 HNF4G PEG10

9.23e-04891367GO:0008270
GeneOntologyMolecularFunctionnuclear steroid receptor activity

PPARA NR3C1

9.24e-0425362GO:0003707
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

LMO3 PPARA FOXA1 LMO1 CREM

3.69e-03582365GO:0140297
GeneOntologyMolecularFunctiontransition metal ion binding

DUSP12 ZC3HC1 ZNF84 PPARA NR3C1 HNF4G PEG10

4.75e-031189367GO:0046914
GeneOntologyBiologicalProcesspositive regulation of intracellular steroid hormone receptor signaling pathway

LMO3 NR3C1 FOXA1

3.91e-0618363GO:0033145
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

LMO3 ZNF225 PPARA NR3C1 ARID4B FOXA1 FOXA2 LMO1 HNF4G CREM ZFY

1.56e-0513903611GO:0045944
GeneOntologyBiologicalProcesspositive regulation of dopaminergic neuron differentiation

FOXA1 FOXA2

1.77e-054362GO:1904340
GeneOntologyBiologicalProcesspositive regulation of glucocorticoid receptor signaling pathway

LMO3 NR3C1

4.42e-056362GO:2000324
GeneOntologyBiologicalProcesshormone-mediated signaling pathway

LHCGR LMO3 PPARA NR3C1 FOXA1

6.21e-05244365GO:0009755
GeneOntologyBiologicalProcessregulation of steroid metabolic process

LHCGR ABCG4 NR3C1 FOXA2

8.79e-05135364GO:0019218
GeneOntologyBiologicalProcesssteroid hormone receptor signaling pathway

LMO3 PPARA NR3C1 FOXA1

1.50e-04155364GO:0043401
GeneOntologyBiologicalProcesspositive regulation of cell-cell adhesion mediated by cadherin

FOXA1 FOXA2

1.61e-0411362GO:2000049
GeneOntologyBiologicalProcessregulation of dopaminergic neuron differentiation

FOXA1 FOXA2

1.93e-0412362GO:1904338
GeneOntologyBiologicalProcessregulation of glucocorticoid receptor signaling pathway

LMO3 NR3C1

1.93e-0412362GO:2000322
GeneOntologyBiologicalProcessnuclear receptor-mediated glucocorticoid signaling pathway

LMO3 NR3C1

3.96e-0417362GO:0042921
GeneOntologyBiologicalProcessregulation of miRNA transcription

PPARA NR3C1 FOXA1

4.08e-0483363GO:1902893
GeneOntologyBiologicalProcessmiRNA transcription

PPARA NR3C1 FOXA1

4.22e-0484363GO:0061614
GeneOntologyBiologicalProcessnuclear receptor-mediated corticosteroid signaling pathway

LMO3 NR3C1

4.45e-0418362GO:0031958
GeneOntologyBiologicalProcessregulation of intracellular steroid hormone receptor signaling pathway

LMO3 NR3C1 FOXA1

4.68e-0487363GO:0033143
GeneOntologyBiologicalProcessparental behavior

NR3C1 ZFY

6.09e-0421362GO:0060746
GeneOntologyBiologicalProcessregulation of cell-cell adhesion mediated by cadherin

FOXA1 FOXA2

6.09e-0421362GO:2000047
GeneOntologyBiologicalProcessregulation of carbohydrate metabolic process

LHCGR PPARA NR3C1 FOXA2

6.81e-04231364GO:0006109
GeneOntologyBiologicalProcessregulation of cardiac muscle tissue growth

PPARA NR3C1 CXADR

7.03e-04100363GO:0055021
GeneOntologyBiologicalProcessregulation of lipid metabolic process

LHCGR ABCG4 PPARA NR3C1 FOXA2

7.26e-04415365GO:0019216
GeneOntologyBiologicalProcessintracellular receptor signaling pathway

LMO3 PPARA NR3C1 FOXA1 HNF4G

7.34e-04416365GO:0030522
GeneOntologyBiologicalProcessregulation of miRNA metabolic process

PPARA NR3C1 FOXA1

7.66e-04103363GO:2000628
GeneOntologyBiologicalProcesscellular response to steroid hormone stimulus

LMO3 PPARA NR3C1 FOXA1

7.74e-04239364GO:0071383
GeneOntologyBiologicalProcessregulation of steroid hormone biosynthetic process

LHCGR NR3C1

7.98e-0424362GO:0090030
GeneOntologyBiologicalProcessregulation of steroid biosynthetic process

LHCGR ABCG4 NR3C1

8.33e-04106363GO:0050810
GeneOntologyBiologicalProcessregulation of heart growth

PPARA NR3C1 CXADR

8.56e-04107363GO:0060420
GeneOntologyBiologicalProcessregulation of lipid biosynthetic process

LHCGR ABCG4 PPARA NR3C1

8.62e-04246364GO:0046890
GeneOntologyBiologicalProcessdorsal/ventral neural tube patterning

FOXA1 FOXA2

8.66e-0425362GO:0021904
GeneOntologyBiologicalProcessregulation of small molecule metabolic process

LHCGR ABCG4 PPARA NR3C1 FOXA2

8.87e-04434365GO:0062012
GeneOntologyBiologicalProcessmiRNA metabolic process

PPARA NR3C1 FOXA1

1.16e-03119363GO:0010586
DomainFork-head_N

FOXA1 FOXA2

9.64e-063342IPR013638
DomainForkhead_N

FOXA1 FOXA2

9.64e-063342PF08430
DomainForkhead_box_C

FOXA1 FOXA2

9.64e-063342IPR018533
DomainHNF_C

FOXA1 FOXA2

9.64e-063342PF09354
Domainzf-C4

PPARA NR3C1 HNF4G

7.93e-0546343PF00105
DomainNUCLEAR_REC_DBD_1

PPARA NR3C1 HNF4G

7.93e-0546343PS00031
DomainZnf_hrmn_rcpt

PPARA NR3C1 HNF4G

7.93e-0546343IPR001628
DomainNuclear_hrmn_rcpt

PPARA NR3C1 HNF4G

7.93e-0546343IPR001723
DomainZnF_C4

PPARA NR3C1 HNF4G

7.93e-0546343SM00399
DomainNUCLEAR_REC_DBD_2

PPARA NR3C1 HNF4G

7.93e-0546343PS51030
Domain-

PPARA NR3C1 HNF4G

8.46e-05473431.10.565.10
DomainHOLI

PPARA NR3C1 HNF4G

9.01e-0548343SM00430
DomainNucl_hrmn_rcpt_lig-bd

PPARA NR3C1 HNF4G

9.01e-0548343IPR000536
DomainHormone_recep

PPARA NR3C1 HNF4G

9.01e-0548343PF00104
Domain-

PPARA NR3C1 HNF4G

1.51e-04573433.30.50.10
DomainZnf_NHR/GATA

PPARA NR3C1 HNF4G

1.59e-0458343IPR013088
DomainZINC_FINGER_C2H2_2

DUSP12 ZNF84 ZNF223 ZNF225 ZNF230 ZFY ZNF222

4.16e-04775347PS50157
DomainKRAB

ZNF84 ZNF223 ZNF225 ZNF230 ZNF222

4.43e-04358345PS50805
DomainKRAB

ZNF84 ZNF223 ZNF225 ZNF230 ZNF222

4.43e-04358345PF01352
DomainKRAB

ZNF84 ZNF223 ZNF225 ZNF230 ZNF222

5.09e-04369345SM00349
DomainKRAB

ZNF84 ZNF223 ZNF225 ZNF230 ZNF222

5.15e-04370345IPR001909
DomainZnf_C2H2

DUSP12 ZNF84 ZNF223 ZNF225 ZNF230 ZFY ZNF222

5.22e-04805347IPR007087
Domain-

ZNF84 ZNF223 ZNF225 ZNF230 ZFY ZNF222

1.27e-036793463.30.160.60
Domainzf-C2H2

ZNF84 ZNF223 ZNF225 ZNF230 ZFY ZNF222

1.41e-03693346PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF84 ZNF223 ZNF225 ZNF230 ZFY ZNF222

1.42e-03694346IPR013087
DomainZINC_FINGER_C2H2_1

ZNF84 ZNF223 ZNF225 ZNF230 ZFY ZNF222

2.52e-03777346PS00028
DomainZnf_C2H2-like

ZNF84 ZNF223 ZNF225 ZNF230 ZFY ZNF222

2.85e-03796346IPR015880
DomainZnF_C2H2

ZNF84 ZNF223 ZNF225 ZNF230 ZFY ZNF222

3.07e-03808346SM00355
DomainTF_fork_head_CS_2

FOXA1 FOXA2

3.17e-0346342IPR030456
DomainTF_fork_head_CS_1

FOXA1 FOXA2

3.30e-0347342IPR018122
DomainFORK_HEAD_3

FOXA1 FOXA2

3.59e-0349342PS50039
DomainFH

FOXA1 FOXA2

3.59e-0349342SM00339
DomainFORK_HEAD_1

FOXA1 FOXA2

3.59e-0349342PS00657
DomainFORK_HEAD_2

FOXA1 FOXA2

3.59e-0349342PS00658
DomainForkhead

FOXA1 FOXA2

3.59e-0349342PF00250
DomainFork_head_dom

FOXA1 FOXA2

3.59e-0349342IPR001766
DomainLIM

LMO3 LMO1

6.99e-0369342PF00412
Domain-

LMO3 LMO1

7.19e-03703422.10.110.10
DomainLIM_DOMAIN_2

LMO3 LMO1

7.39e-0371342PS50023
DomainZnf_LIM

LMO3 LMO1

7.39e-0371342IPR001781
DomainLIM_DOMAIN_1

LMO3 LMO1

7.39e-0371342PS00478
DomainLIM

LMO3 LMO1

7.39e-0371342SM00132
PathwayPID_HNF3B_PATHWAY

NR3C1 FOXA1 FOXA2

1.05e-0445293M106
PathwayREACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY

PPARA NR3C1 HNF4G

1.71e-0453293M8276
PathwayREACTOME_FORMATION_OF_AXIAL_MESODERM

FOXA1 FOXA2

3.66e-0414292M46441
PathwayREACTOME_CIRCADIAN_CLOCK

PPARA NR3C1 CREM

3.91e-0470293M938
PathwayWP_FOXA2_PATHWAY

FOXA1 FOXA2

8.38e-0421292M42579
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS

FOXA2 HNF4G

8.38e-0421292M14966
PathwayKEGG_MATURITY_ONSET_DIABETES_OF_THE_YOUNG

FOXA2 HNF4G

1.19e-0325292M18312
Pubmed

Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.

ZNF223 ZNF225 ZNF230 ZNF222

4.63e-092036412743021
Pubmed

Glucocorticoid Receptor β Induces Hepatic Steatosis by Augmenting Inflammation and Inhibition of the Peroxisome Proliferator-activated Receptor (PPAR) α.

PPARA NR3C1

1.04e-06236227784782
Pubmed

Foxa1 and Foxa2 interact with the androgen receptor to regulate prostate and epididymal genes differentially.

FOXA1 FOXA2

1.04e-06236216467259
Pubmed

PPARalpha blocks glucocorticoid receptor alpha-mediated transactivation but cooperates with the activated glucocorticoid receptor alpha for transrepression on NF-kappaB.

PPARA NR3C1

1.04e-06236219376972
Pubmed

The pioneer transcription factors Foxa1 and Foxa2 regulate alternative RNA splicing during thymocyte positive selection.

FOXA1 FOXA2

1.04e-06236234323272
Pubmed

Transcription factors FOXA1 and FOXA2 maintain dopaminergic neuronal properties and control feeding behavior in adult mice.

FOXA1 FOXA2

1.04e-06236226283356
Pubmed

Pioneer Factors FOXA1 and FOXA2 Assist Selective Glucocorticoid Receptor Signaling in Human Endometrial Cells.

FOXA1 FOXA2

1.04e-06236228938408
Pubmed

Differential induction of HNF-3 transcription factors during neuronal differentiation.

FOXA1 FOXA2

1.04e-0623629260895
Pubmed

Hepatic deficiency of the pioneer transcription factor FoxA restricts hepatitis B virus biosynthesis by the developmental regulation of viral DNA methylation.

FOXA1 FOXA2

1.04e-06236228235042
Pubmed

Chromatin accessibility and pioneer factor FOXA1 restrict glucocorticoid receptor action in prostate cancer.

NR3C1 FOXA1

1.04e-06236238015476
Pubmed

Chromatin recruitment of activated AMPK drives fasting response genes co-controlled by GR and PPARα.

PPARA NR3C1

1.04e-06236227576532
Pubmed

Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors.

FOXA1 FOXA2

1.04e-06236234789735
Pubmed

Transcription factors Foxa1 and Foxa2 are required for adult dopamine neurons maintenance.

FOXA1 FOXA2

1.04e-06236225249938
Pubmed

Glucocorticoid receptor-PPARα axis in fetal mouse liver prepares neonates for milk lipid catabolism.

PPARA NR3C1

1.04e-06236227367842
Pubmed

Human but not mouse adipogenesis is critically dependent on LMO3.

LMO3 NR3C1

1.04e-06236223823477
Pubmed

Foxa1 and Foxa2 are essential for sexual dimorphism in liver cancer.

FOXA1 FOXA2

1.04e-06236222265403
Pubmed

Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues.

FOXA1 FOXA2

1.04e-06236215567715
Pubmed

The evolutionarily ancient FOXA transcription factors shape the murine gut microbiome via control of epithelial glycosylation.

FOXA1 FOXA2

1.04e-06236238821056
Pubmed

FOXA1/2 depletion drives global reprogramming of differentiation state and metabolism in a human liver cell line and inhibits differentiation of human stem cell-derived hepatic progenitor cells.

FOXA1 FOXA2

1.04e-06236236515690
Pubmed

Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in mice.

FOXA1 FOXA2

1.04e-06236219737569
Pubmed

Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus.

FOXA1 FOXA2

1.04e-06236225211022
Pubmed

Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer.

FOXA1 FOXA2

1.04e-06236220160041
Pubmed

Meta-Analysis of Transcriptome Data Related to Hippocampus Biopsies and iPSC-Derived Neuronal Cells from Alzheimer's Disease Patients Reveals an Association with FOXA1 and FOXA2 Gene Regulatory Networks.

FOXA1 FOXA2

1.04e-06236226890743
Pubmed

Negative regulation of hepatitis B virus replication by forkhead box protein A in human hepatoma cells.

FOXA1 FOXA2

1.04e-06236225836733
Pubmed

Nucleosome-binding affinity as a primary determinant of the nuclear mobility of the pioneer transcription factor FoxA.

FOXA1 FOXA2

1.04e-06236219339686
Pubmed

A Druggable FOXA1-Glucocorticoid Receptor Transcriptional Axis Drives Tumor Growth in a Subset of Non-Small Cell Lung Cancer.

NR3C1 FOXA1

1.04e-06236237691854
Pubmed

Foxa1 and Foxa2 regulate bile duct development in mice.

FOXA1 FOXA2

1.04e-06236220347503
Pubmed

Foxa (HNF3) up-regulates vitronectin expression during retinoic acid-induced differentiation in mouse neuroblastoma Neuro2a cells.

FOXA1 FOXA2

1.04e-06236212441652
Pubmed

Foxa1 and Foxa2 in thymic epithelial cells (TEC) regulate medullary TEC and regulatory T-cell maturation.

FOXA1 FOXA2

1.04e-06236230061015
Pubmed

FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth.

FOXA1 FOXA2

3.12e-06336227045898
Pubmed

The human HNF-3 genes: cloning, partial sequence and mutation screening in patients with impaired glucose homeostasis.

FOXA1 FOXA2

3.12e-06336210899756
Pubmed

Expression of LIM protein genes Lmo1, Lmo2, and Lmo3 in adult mouse hippocampus and other forebrain regions: differential regulation by seizure activity.

LMO3 LMO1

3.12e-0633629204936
Pubmed

FoxO1 and FoxA1/2 form a complex on DNA and cooperate to open chromatin at insulin-regulated genes.

FOXA1 FOXA2

3.12e-06336230142277
Pubmed

FoxA-dependent demethylation of DNA initiates epigenetic memory of cellular identity.

FOXA1 FOXA2

3.12e-06336233636105
Pubmed

Protein or amino acid deprivation differentially regulates the hepatic forkhead box protein A (FOXA) genes through an activating transcription factor-4-independent pathway.

FOXA1 FOXA2

3.12e-06336219415718
Pubmed

Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head.

FOXA1 FOXA2

3.12e-0633621672118
Pubmed

The HNF-3 gene family of transcription factors in mice: gene structure, cDNA sequence, and mRNA distribution.

FOXA1 FOXA2

3.12e-0633628034310
Pubmed

Forkhead box transcription factors Foxa1 and Foxa2 are important regulators of Muc2 mucin expression in intestinal epithelial cells.

FOXA1 FOXA2

3.12e-06336218336786
Pubmed

Assignment of the human genes for hepatocyte nuclear factor 3-alpha, -beta, and -gamma (HNF3A, HNF3B, HNF3G) to 14q12-q13, 20p11, and 19q13.2-q13.4.

FOXA1 FOXA2

3.12e-0633629119385
Pubmed

Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 alpha, beta and gamma genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm.

FOXA1 FOXA2

3.12e-0633628187630
Pubmed

PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal.

PPARA NR3C1

3.12e-06336225970251
Pubmed

Foxa1 and Foxa2 regulate bile duct development in mice.

FOXA1 FOXA2

3.12e-06336219436110
Pubmed

Exon-I is involved in positive as well as negative regulation of human angiotensinogen gene expression.

FOXA1 FOXA2

3.12e-0633629931457
Pubmed

Molecular mechanisms of liver development and differentiation.

FOXA1 FOXA2

3.12e-06336210600708
Pubmed

Loss of Interdependent Binding by the FoxO1 and FoxA1/A2 Forkhead Transcription Factors Culminates in Perturbation of Active Chromatin Marks and Binding of Transcriptional Regulators at Insulin-sensitive Genes.

FOXA1 FOXA2

3.12e-06336226929406
Pubmed

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.

FOXA1 FOXA2

3.12e-06336226551672
Pubmed

Forkhead box A1 (FOXA1) and A2 (FOXA2) oppositely regulate human type 1 iodothyronine deiodinase gene in liver.

FOXA1 FOXA2

3.12e-06336222067325
Pubmed

Chromatin remodeling mediated by the FOXA1/A2 transcription factors activates CFTR expression in intestinal epithelial cells.

FOXA1 FOXA2

3.12e-06336224440874
Pubmed

Null mutation of the Lmo4 gene or a combined null mutation of the Lmo1/Lmo3 genes causes perinatal lethality, and Lmo4 controls neural tube development in mice.

LMO3 LMO1

3.12e-06336214966285
Pubmed

Hepatocyte nuclear factor 3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic function.

FOXA1 FOXA2

3.12e-0633628248124
Pubmed

The initiation of liver development is dependent on Foxa transcription factors.

FOXA1 FOXA2

3.12e-06336215959514
Pubmed

A census of human transcription factors: function, expression and evolution.

PPARA NR3C1 ZNF230 FOXA1 FOXA2 HNF4G CREM ZFY

3.31e-0690836819274049
Pubmed

Hepatocyte-specific HDAC3 ablation promotes hepatocellular carcinoma in females by suppressing Foxa1/2.

FOXA1 FOXA2

6.24e-06436237752418
Pubmed

ErbB3 binding protein 1 represses metastasis-promoting gene anterior gradient protein 2 in prostate cancer.

FOXA1 FOXA2

6.24e-06436220048076
Pubmed

Integrative genomic analysis identifies that SERPINA6-rs1998056 regulated by FOXA/ERα is associated with female hepatocellular carcinoma.

FOXA1 FOXA2

6.24e-06436225198130
Pubmed

Overexpression of transcription factor FoxA2 in the developing skeleton causes an enlargement of the cartilage hypertrophic zone, but it does not trigger ectopic differentiation in immature chondrocytes.

FOXA1 FOXA2

6.24e-06436235398294
Pubmed

The expression of p21 is upregulated by forkhead box A1/2 in p53-null H1299 cells.

FOXA1 FOXA2

6.24e-06436225281925
Pubmed

Association between hepatocyte nuclear factor 6 (HNF-6) and FoxA2 DNA binding domains stimulates FoxA2 transcriptional activity but inhibits HNF-6 DNA binding.

FOXA1 FOXA2

6.24e-06436212509444
Pubmed

LIM-domain-only proteins: multifunctional nuclear transcription coregulators that interacts with diverse proteins.

LMO3 LMO1

6.24e-06436224379077
Pubmed

Collapse of the hepatic gene regulatory network in the absence of FoxA factors.

FOXA1 FOXA2

6.24e-06436232561546
Pubmed

Reprogramming of glucocorticoid receptor function by hypoxia.

PPARA NR3C1

6.24e-06436234699114
Pubmed

The ratio of FoxA1 to FoxA2 in lung adenocarcinoma is regulated by LncRNA HOTAIR and chromatin remodeling factor LSH.

FOXA1 FOXA2

6.24e-06436226658322
Pubmed

Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles.

PPARA FOXA1 ZFY

7.72e-063736319865483
Pubmed

Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues.

FOXA1 FOXA2

1.04e-0553629032290
Pubmed

Foxa1 and Foxa2 orchestrate development of the urethral tube and division of the embryonic cloaca through an autoregulatory loop with Shh.

FOXA1 FOXA2

1.04e-05536232645357
Pubmed

FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancer.

FOXA1 FOXA2

1.04e-05536230475207
Pubmed

A hepatocyte nuclear factor-3 site in the fibrinogen beta promoter is important for interleukin 6-induced expression, and its activity is influenced by the adjacent -148C/T polymorphism.

FOXA1 FOXA2

1.04e-05536215737987
Pubmed

FoxA proteins regulate H19 endoderm enhancer E1 and exhibit developmental changes in enhancer binding in vivo.

FOXA1 FOXA2

1.04e-05536215485926
Pubmed

Chronological expression of Ciliated Bronchial Epithelium 1 during pulmonary development.

FOXA1 FOXA2

1.04e-05536219213785
Pubmed

Physical and functional interactions between homeodomain NKX2.1 and winged helix/forkhead FOXA1 in lung epithelial cells.

FOXA1 FOXA2

1.04e-05536217220277
Pubmed

Conditional regulation of the human CYP4X1 and CYP4Z1 genes.

PPARA NR3C1

1.04e-05536215797250
Pubmed

A GO catalogue of human DNA-binding transcription factors.

ZNF223 ZNF230 ZNF222

1.14e-054236334673265
Pubmed

Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors.

NR3C1 FOXA1 FOXA2

1.40e-054536322696295
Pubmed

Islet α-, β-, and δ-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor.

LMO3 FOXA2 LMO1

1.40e-054536323193182
Pubmed

Foxa2 activity increases plasma high density lipoprotein levels by regulating apolipoprotein M.

FOXA1 FOXA2

1.56e-05636218381283
Pubmed

The zinc finger-containing transcription factor Gata-4 is expressed in the developing endocrine pancreas and activates glucagon gene expression.

FOXA1 FOXA2

1.56e-05636215539431
Pubmed

Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo.

FOXA1 FOXA2

1.56e-0563628375339
Pubmed

Expression of Foxa transcription factors in the developing and adult murine prostate.

FOXA1 FOXA2

1.56e-05636215389796
Pubmed

Foxa1 is essential for development and functional integrity of the subthalamic nucleus.

FOXA1 FOXA2

2.18e-05736227934886
Pubmed

Differential interaction of steroid hormone receptors with LXXLL motifs in SRC-1a depends on residues flanking the motif.

PPARA NR3C1

2.18e-05736210731636
Pubmed

GATA-4/-6 and HNF-1/-4 families of transcription factors control the transcriptional regulation of the murine Muc5ac mucin during stomach development and in epithelial cancer cells.

FOXA2 HNF4G

2.18e-05736222554936
Pubmed

FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma.

FOXA1 FOXA2

2.18e-05736235835117
Pubmed

Multiple roles for activin-like kinase-2 signaling during mouse embryogenesis.

FOXA1 FOXA2

2.18e-05736210479450
Pubmed

Members of the HNF-3/forkhead family of transcription factors exhibit distinct cellular expression patterns in lung and regulate the surfactant protein B promoter.

FOXA1 FOXA2

2.18e-0573627958446
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

LMO3 PPARA NR3C1 FOXA1 LMO1 HNF4G ZFY

2.79e-0587736720211142
Pubmed

The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo.

FOXA1 FOXA2

2.91e-0583628069910
Pubmed

Wnt signaling maintains the notochord fate for progenitor cells and supports the posterior extension of the notochord.

FOXA1 FOXA2

2.91e-05836219720144
Pubmed

The winged helix transcriptional activator HFH-8 is expressed in the mesoderm of the primitive streak stage of mouse embryos and its cellular derivatives.

FOXA1 FOXA2

2.91e-0583629486531
Pubmed

The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins.

FOXA1 FOXA2

2.91e-0583628306889
Pubmed

HNF-3 beta as a regulator of floor plate development.

FOXA1 FOXA2

2.91e-0583628287471
Pubmed

Early postnatal lethality in Hoxa-5 mutant mice is attributable to respiratory tract defects.

FOXA1 FOXA2

3.73e-0593629441679
Pubmed

Conserved linkage of NK-2 homeobox gene pairs Nkx2-2/2-4 and Nkx2-1/2-9 in mammals.

FOXA1 FOXA2

3.73e-05936210818213
Pubmed

Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell.

FOXA1 FOXA2

3.73e-05936220534694
Pubmed

Stage-specific regulation of respiratory epithelial cell differentiation by Foxa1.

FOXA1 FOXA2

3.73e-05936216214823
Pubmed

Quantitative gene expression profiling reveals a fetal hepatic phenotype of murine ES-derived hepatocytes.

FOXA1 FOXA2

4.66e-051036215005571
Pubmed

Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation.

FOXA1 FOXA2

4.66e-051036215987773
Pubmed

Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression.

PPARA NR3C1

4.66e-051036215870285
Pubmed

Genetic patterning of the posterior neuropore region of curly tail mouse embryos: deficiency of Wnt5a expression.

FOXA1 FOXA2

4.66e-05103629712518
Pubmed

The onecut transcription factor HNF6 is required for normal development of the biliary tract.

FOXA1 FOXA2

4.66e-051036211934848
Pubmed

Genetic patterning of the developing mouse tail at the time of posterior neuropore closure.

FOXA1 FOXA2

4.66e-05103629415428
InteractionONECUT1 interactions

NR3C1 FOXA1 FOXA2

5.22e-0710343int:ONECUT1
InteractionZNF84 interactions

LMO3 ZNF84 LMO1

1.24e-0613343int:ZNF84
InteractionNCOA1 interactions

PPARA NR3C1 FOXA2 HNF4G CXADR

4.38e-06146345int:NCOA1
Cytoband19q13.2

ZNF223 ZNF225 ZNF222

2.93e-0416436319q13.2
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF223 ZNF225 ZNF230 FBXO46 ZNF222

2.26e-031192365chr19q13
GeneFamilyNuclear hormone receptors

PPARA NR3C1 HNF4G

9.64e-054933371
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF84 ZNF223 ZNF225 ZNF230 ZFY ZNF222

1.70e-0371833628
GeneFamilyForkhead boxes

FOXA1 FOXA2

2.78e-0343332508
GeneFamilyLIM domain containing

LMO3 LMO1

5.18e-03593321218
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 IGSF5 PPARA FOXA2 CXADR

2.70e-0717835576e71fff99cf64302e2e3c0d66dd8ba0ff13624e
ToppCelldroplet-Lung-30m-Epithelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 IGSF5 PPARA FOXA2 CXADR

2.70e-071783555442bc52b8e902da1383f44d97a9f95e471a8d4d
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 IGSF5 PPARA FOXA2 CXADR

2.70e-0717835582f78ea1ea3ff3e2347cd8bc2f06e2a10e96f220
ToppCelldroplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 IGSF5 PPARA FOXA2 CXADR

2.70e-07178355523b286ebe0359c7f1902f28cbd71f452626fc0d
ToppCellPND07-28-samps-Epithelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TRPM6 IGSF5 FOXA1 FOXA2 CXADR

3.10e-07183355a98f1d71d82ed6cca996f74352ab834fb6e95206
ToppCelldroplet-Lung-nan-21m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 C6 FOXA1 FOXA2 CXADR

3.27e-071853550e7351cd6d6e6e8c29573042e168da50ee496cfc
ToppCelldroplet-Lung-nan-21m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 C6 FOXA1 FOXA2 CXADR

3.27e-071853556938ac3cab536cf8a474eba441ce6dcdfcc43b53
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

LMO3 FOXA1 FOXA2 PEG10 CXADR

3.45e-0718735511670a85db87cbb3e78022a589632173604b0940
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

LMO3 FOXA1 FOXA2 PEG10 CXADR

3.45e-071873550277d4e54bd4d48f30241c2951a569209423fee8
ToppCelldroplet-Lung-21m-Epithelial-alveolar_epithelial-type_II_pneumocyte|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 C6 FOXA1 FOXA2 CXADR

3.54e-07188355068b761a7b6778bc6d6c776b5f09094aac87477e
ToppCelldroplet-Lung-21m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 C6 FOXA1 FOXA2 CXADR

3.54e-07188355c95134245dab9057eb1f9b54acb371470f9c8b86
ToppCelldroplet-Lung-21m-Epithelial-alveolar_epithelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 C6 FOXA1 FOXA2 CXADR

3.54e-071883553ee321a74f04eb0982c7b4977426946b0ae6e5a9
ToppCelldroplet-Lung-21m-Epithelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 C6 FOXA1 FOXA2 CXADR

3.73e-0719035550a8ba20f8153279387c335538bc52bf18ac1fc2
ToppCellfacs-Lung-EPCAM-3m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF5 C6 FOXA1 FOXA2 CXADR

3.83e-07191355629007189034ee8451411428f1c6cc57daee2d91
ToppCelldroplet-Lung-18m-Epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 C6 FOXA1 FOXA2 CXADR

3.83e-071913551b59f1cad6c1a6a5938afa9195164918e3ff4e86
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 C6 FOXA1 FOXA2 CXADR

3.93e-0719235513e4b17d7a592604140777aca235f795df6b3f91
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 C6 FOXA1 FOXA2 CXADR

3.93e-07192355f51b3fd962263920a6cae783ca7af13f5eb7aaa3
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 C6 FOXA1 FOXA2 CXADR

3.93e-071923556244541688f85917018a057aa0b3e5972934dfbc
ToppCellfacs-Lung-nan-3m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 C6 FOXA1 FOXA2 CXADR

3.93e-07192355cca2d0fedfbd946c54d6f4fc45887117c8dae58a
ToppCellfacs-Lung-3m-Epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IGSF5 C6 FOXA1 FOXA2 CXADR

4.03e-07193355db5e43e0b571737e7006365bdf0575340b8b900b
ToppCellP28-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TRPM6 C6 FOXA1 FOXA2

9.40e-06170354d0ed3a8a7ad96c05641ec409b0a69c4fb094893c
ToppCellP07-Epithelial|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

C6 FOXA1 FOXA2 CXADR

1.01e-051733548b10087a917b825809d35a2b2b349c73a2782472
ToppCellP07-Epithelial-alveolar_epithelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IGSF5 FOXA1 FOXA2 CXADR

1.03e-051743542739de68e0266054694f99807cfb1f07b6bbb371
ToppCelldroplet-Lung-LUNG-30m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 IGSF5 FOXA2 CXADR

1.08e-051763545201f003192c033655ba47f0faf8c47a96eae03d
ToppCellfacs-Lung-nan-3m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C6 FOXA1 FOXA2 CXADR

1.10e-05177354b37d821f4f3204daf7c568ac17a0af0ba97273d6
ToppCellfacs-Lung-nan-3m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C6 FOXA1 FOXA2 CXADR

1.10e-05177354e5070934c674a46e070b0d52b9a374516bf6aea1
ToppCellP15-Epithelial|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

C6 FOXA1 FOXA2 CXADR

1.15e-05179354869d3d203e2cb88636e2f0c4476c72571ae3b5ca
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPDYA LMO3 FOXA2 CXADR

1.20e-051813540513b9e6673ff7bf8e72ba123ca3794b65d10170
ToppCellP15-Epithelial-alveolar_epithelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

C6 FOXA1 FOXA2 CXADR

1.20e-051813547033be0ba90556f7e5f7c0d4a9f7644afcb22c9b
ToppCelldroplet-Lung-nan-21m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 FOXA1 FOXA2 CXADR

1.23e-0518235440539ade8c3cd12b61f1cd0d493828e58282796b
ToppCellPND07-28-samps-Epithelial-Alveolar_epithelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TRPM6 C6 FOXA2 CXADR

1.26e-0518335423e55f88a802a9299d2773f9394970e86e8bbfaa
ToppCellPND07-28-samps-Epithelial-Alveolar_epithelial-AT2|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TRPM6 C6 FOXA2 CXADR

1.26e-051833540a69e22750dd8b66ab988cf36d0dd2b59e2f7d26
ToppCellE12.5-Epithelial-airway_epithelial_cell-club_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IGSF5 FOXA1 FOXA2 CXADR

1.28e-05184354a69c3c57cd939b2888f548a0fbca3392ad310445
ToppCellP28-Epithelial|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IGSF5 FOXA1 FOXA2 CXADR

1.28e-0518435405811d13bd8a602095a3fcf5e55345edadc7b8bf
ToppCellE12.5-Epithelial-airway_epithelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IGSF5 FOXA1 FOXA2 CXADR

1.28e-051843543df78b17098b50e1a7f2c8791bf2d0806328330a
ToppCellPND01-03-samps-Epithelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

TRPM6 IGSF5 FOXA2 CXADR

1.31e-051853542b854df79cfe2cb4d2f9c2938a066e0aa3649325
ToppCellP28-Epithelial-alveolar_epithelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IGSF5 FOXA1 FOXA2 CXADR

1.31e-051853545bb513e569f3a197d55ae2ca683e202daebabeac
ToppCellfacs-Lung-EPCAM-24m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 IGSF5 FOXA1 CXADR

1.34e-051863543c4994a1a7db06a61da8170e45e06aaef7896592
ToppCellfacs-Lung-EPCAM-24m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 IGSF5 FOXA1 CXADR

1.34e-05186354a583d6fc0f1e729f6e9fd18d7b49d6eab9ca32b9
ToppCellfacs-Lung-EPCAM-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 IGSF5 C6 FOXA2

1.40e-051883543dd571bd8e7358b4346dea71f6bf9602dabf583c
ToppCell15-Distal-Epithelial-Secretory_progenitor|Distal / Age, Tissue, Lineage and Cell class

LMO3 FOXA1 FOXA2 CXADR

1.40e-051883549a64fb07de611de38d6f24673feb3b81a5e85384
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 IGSF5 C6 FOXA2

1.40e-05188354b1049003ca79c340bb8c78da66bdc0956e1aebc2
ToppCelldroplet-Lung-nan-18m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 C6 FOXA1 FOXA2

1.43e-05189354e5325f1c7430b574947f8ee67e425455b60dc518
ToppCelldroplet-Lung-nan-18m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 C6 FOXA1 FOXA2

1.43e-05189354ca657353f2b649530809c0bc057e448adc511ec1
ToppCelldroplet-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 C6 FOXA1 FOXA2

1.46e-05190354a51405f8466fc6d4087873137472619b2e84c1da
ToppCelldroplet-Lung-nan-18m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 FOXA1 FOXA2 CXADR

1.46e-05190354b057bea6e55cef872290893b6e439bbcdcee2f2e
ToppCellpdx-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PPARA C6 NR3C1 PEG10

1.46e-05190354b05db0de9b6ae01dd30074453f7de44f7397631e
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 FOXA1 FOXA2 CXADR

1.46e-05190354aaf5f1c1ff7b1454f4e5dacfeb48e1c3627e3372
ToppCelldroplet-Lung-18m-Epithelial-alveolar_epithelial-type_II_pneumocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 C6 FOXA1 FOXA2

1.46e-05190354059beca1c92181b8ba4dcd6fc71ff7530d83d0de
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 FOXA1 FOXA2 CXADR

1.46e-05190354a20123d5c6cb8c2f0dfd99bbfdb571a73c36234d
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 IGSF5 C6 FOXA2

1.49e-05191354f98fc372e579ce69409afbbe0f83c03c7ea62632
ToppCell15-Airway-Epithelial-Secretory_progenitor|Airway / Age, Tissue, Lineage and Cell class

LMO3 FOXA1 FOXA2 CXADR

1.49e-051913549359d8c6b00f8977848986baf3c950157adf4c9a
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRPM6 C6 FOXA2 CXADR

1.49e-051913542f71f1fb6b5872d84860840b22e789a87ab14eec
ToppCellE15.5-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FOXA1 FOXA2 LMO1 CXADR

1.49e-05191354402c341b00f98e8215458766b3c219fff8dcb447
ToppCelldroplet-Lung-18m-Epithelial-alveolar_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 C6 FOXA1 FOXA2

1.49e-05191354caed913e7ede9f8ae3af273d1ecf375de6c5e813
ToppCell367C-Epithelial_cells|367C / Donor, Lineage, Cell class and subclass (all cells)

LMO3 FOXA1 FOXA2 CXADR

1.49e-05191354d31975fc33779b0b3ff1a50d7c64fec8d08be4d4
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 IGSF5 C6 FOXA2

1.49e-05191354210589095a3f5d5117174caf6ec110b502f27030
ToppCellPND14-Epithelial-Epithelial_Alveolar|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRPM6 C6 FOXA2 CXADR

1.49e-051913545f8b3b2d38b37027901db9a1cccdbd1ff70f29de
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 IGSF5 C6 FOXA2

1.52e-051923544a46f7980ec145be5b4bf8b98265e3e0f2ea4c63
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGSF5 C6 FOXA2 CXADR

1.52e-05192354f206c015f091234e2c86dfa66926e97b2ea99690
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Club|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

LMO3 FOXA1 FOXA2 CXADR

1.52e-05192354044c7ae56da17cacf2705efa8ac2c8aeba6cfeee
ToppCellPND28-Epithelial-Epithelial_Alveolar|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IGSF5 C6 FOXA2 CXADR

1.52e-0519235469963e8dc6d6368243e61da133484eb23225625a
ToppCellE15.5-Epithelial-alveolar_epithelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FOXA1 FOXA2 LMO1 CXADR

1.52e-05192354567f4355a01aae1f2eafc16fe86d1538a62030ab
ToppCellfacs-Lung-24m-Epithelial-alveolar_epithelial-type_II_pneumocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 IGSF5 FOXA1 CXADR

1.55e-0519335468adc680deb2f1a29d3cca19c13b9f6271dd4d60
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor|E16.5-samps / Age Group, Lineage, Cell class and subclass

IGSF5 FOXA1 FOXA2 CXADR

1.55e-05193354c1817ad675b9f9d2d3436c8b9646edf89f0d4c82
ToppCellfacs-Lung-24m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 IGSF5 FOXA1 CXADR

1.55e-05193354819e6ee2ffa3e31bf9a2d57c99d9e3eac7072765
ToppCellE16.5-samps-Epithelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

IGSF5 FOXA1 FOXA2 CXADR

1.55e-051933541cb5a1cffa2b4a3bfecca16b791c1992edeb237d
ToppCellfacs-Lung-24m-Epithelial-alveolar_epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 IGSF5 FOXA1 CXADR

1.55e-051933544a1b4a2faf741ffba5c84218af4df6a8b2a9f4de
ToppCell(7)_Epithelial-J_(AT1-AT2_progenitors)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

LMO3 MRPL36 PEG10 CXADR

1.61e-0519535470e6b58c502a2abeb4e36bed179020c675468bd4
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LMO3 FOXA2 PEG10 CXADR

1.61e-05195354d9694db6bf239636d1335016878c98f6ee2eb0eb
ToppCell15-Airway-Epithelial|Airway / Age, Tissue, Lineage and Cell class

LMO3 FOXA1 FOXA2 CXADR

1.61e-05195354cd0af7e260e4f0c5a9ecdfa93619f37b2a9308a5
ToppCell11.5-Airway-Epithelial-Secretory_progenitor|Airway / Age, Tissue, Lineage and Cell class

LMO3 FOXA1 FOXA2 CXADR

1.61e-051953548cbc78a6cb812f907c69b00f85263976216840ac
ToppCell11.5-Distal-Epithelial-Secretory_progenitor|Distal / Age, Tissue, Lineage and Cell class

LMO3 FOXA1 FOXA2 CXADR

1.65e-051963542648d64b0e7b59ae78182d55f32699ceea37ff8d
ToppCellcellseq-Epithelial-Epithelial_Alveolar|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LMO3 FOXA2 PEG10 CXADR

1.65e-05196354a7cbe66ebd8931ef2b8ff26a42afce0ad1c48f17
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Club|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

LMO3 FOXA1 FOXA2 CXADR

1.65e-051963544e4c632db73b1340d80bf40a7657cb4821084d3c
ToppCell11.5-Distal-Epithelial-Bud_tip_adjacent|Distal / Age, Tissue, Lineage and Cell class

LMO3 FOXA1 FOXA2 CXADR

1.65e-05196354a6a242868df0d2ff30825624a8d7c0367527594d
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C6 FOXA1 HNF4G CXADR

1.65e-051963544deaadb9796b907b7480fb7af5ed76ebad240850
ToppCelltumor_Lung-T/NK_cells-CD8+/CD4+_Mixed_Th|tumor_Lung / Location, Cell class and cell subclass

NR3C1 ARID4B STK17B CREM

1.68e-05197354de26ca046038e34790cece24529a05d491e6f8ef
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C6 FOXA1 HNF4G CXADR

1.68e-05197354f097e729f515e7945b9482e9f9dbc9536b90f0bb
ToppCell11.5-Airway-Epithelial|Airway / Age, Tissue, Lineage and Cell class

LMO3 FOXA1 FOXA2 CXADR

1.68e-05197354e671af1b69566d97afe97f1a959a07b6f4c05620
ToppCelldistal-Epithelial-Club-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LMO3 FOXA1 FOXA2 PEG10

1.71e-05198354e56a5ffadfa4d1e34d34aec43eaf560cd80286e1
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-AT1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LMO3 FOXA2 PEG10 CXADR

1.71e-0519835454228dd9a50616d2022712d162a419ed0327cabd
ToppCellAT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

LMO3 FOXA2 PEG10 CXADR

1.71e-05198354893036558a9ad86b57f9e735df35812e9d18739e
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LMO3 FOXA1 FOXA2 PEG10

1.75e-05199354a8bfc0b93ad9968cf52a25be86995ffe436bd636
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Transitional_AT2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LMO3 FOXA1 PEG10 CXADR

1.75e-05199354b44d74895846e2ac144438b73e0ca91e3949c16c
ToppCellBiopsy_Control_(H.)-Epithelial-Transitional_AT2|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

LMO3 FOXA2 PEG10 CXADR

1.75e-05199354e04a57a55c724091db353e2b3baf84372d788728
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C6 FOXA1 HNF4G CXADR

1.75e-051993549d24223b571fba202455c5bd49bd79530abf09c0
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C6 FOXA1 HNF4G CXADR

1.75e-05199354722b9ebf7e47c361a7f192689a8d46947ec62b45
ToppCelldistal-Epithelial-Club|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LMO3 FOXA1 FOXA2 PEG10

1.75e-05199354c63ccce1285352927fd8c4f7374ec5fff8d70cec
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Transitional_AT2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LMO3 FOXA1 PEG10 CXADR

1.75e-051993544b374a5de82b4614d3d8a00202ea6cb8f1fd8104
ToppCellEpithelial_cells|World / lung cells shred on cell class, cell subclass, sample id

LMO3 FOXA2 PEG10 CXADR

1.75e-05199354bbe69e44b7970f57628365ae771790f2b13d0cae
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

LMO3 FOXA2 PEG10 CXADR

1.75e-05199354e459d5aa63c83f960562be33cea8182b0556eabf
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Late_airway_progenitor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

LMO3 FOXA1 FOXA2 CXADR

1.75e-05199354494461665f945ce6c97299c58f7785e90dec5812
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_2_alveolar|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

LMO3 FOXA2 PEG10 CXADR

1.75e-05199354e28ace2ca680c6154398e17110aa1838dd7a5548
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Transitional_AT2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

LMO3 FOXA1 PEG10 CXADR

1.75e-051993549e8231c9007d8d963805a4c99e0905538ceb9b60
ToppCelldistal-3-Epithelial-Club|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LMO3 FOXA1 FOXA2 PEG10

1.75e-051993541a0c3506df2438f5be40a8ea72effe5f8ebd35c4
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT2-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

LMO3 FOXA2 PEG10 CXADR

1.78e-0520035435c05cae30cd6b323d2662f1396ddeab08bc75fc
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LMO3 FOXA2 PEG10 CXADR

1.78e-052003543c251ad03fbbdae91dfd9037880ba43adbb03807
ToppCell11.5-Airway|11.5 / Age, Tissue, Lineage and Cell class

LMO3 FOXA1 FOXA2 PEG10

1.78e-052003549e3a8978b76ee9ba1ccc220f128dad081eceba1a
ToppCellmedial-2-Epithelial|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LMO3 FOXA1 FOXA2 CXADR

1.78e-052003540079041c3e654c1ef77c492bdb2f31ce8f4b507b
DrugNSC123116

FOXA1 FOXA2 HNF4G

5.44e-0711353CID000275966
DrugOrlistat, 5

LMO3 PPARA LMO1 CREM

9.08e-0686354CID000004599
Drugandrostenol

PPARA NR3C1 CXADR

9.49e-0627353CID000101989
Diseaselung non-small cell carcinoma (is_marker_for)

NR3C1 FOXA1 FOXA2

8.87e-04169333DOID:3908 (is_marker_for)
Diseaseeosinophil count

ZC3HC1 PPARA NR3C1 FOXA1 FBXO46 STK17B CREM

1.10e-031488337EFO_0004842
Diseasebody mass index, fasting blood glucose measurement

FOXA2 LMO1

1.49e-0351332EFO_0004340, EFO_0004465
Diseaseirritability measurement

PLEKHM1 MYO1H

3.81e-0382332EFO_0009594
DiseaseDrug toxicity

PPARA NR3C1

3.99e-0384332C0013221
DiseaseAdverse reaction to drug

PPARA NR3C1

3.99e-0384332C0041755
Diseaseage at menarche

ZC3HC1 LMO1 HNF4G MYO1H

4.19e-03594334EFO_0004703
Diseasebeta-amyloid 1-42 measurement

TRPM6 MRPL36

4.28e-0387332EFO_0004670
DiseaseFatty Liver

PPARA FOXA1

4.37e-0388332C0015695
DiseaseSteatohepatitis

PPARA FOXA1

4.37e-0388332C2711227
DiseaseProstatic Neoplasms

IGSF5 PPARA NR3C1 FOXA1

4.76e-03616334C0033578
DiseaseMalignant neoplasm of prostate

IGSF5 PPARA NR3C1 FOXA1

4.76e-03616334C0376358
Diseaseovarian carcinoma

MRPL36 PPARA PLEKHM1

5.47e-03321333EFO_0001075
Diseasebody surface area

PPARA NR3C1 LMO1 HNF4G

5.54e-03643334EFO_0022196

Protein segments in the cluster

PeptideGeneStartEntry
KRGKRRYCNTEECLK

ARID4B

821

Q4LE39
YKTLLKCLSGKFCRR

ABCG4

81

Q9H172
KKRCRDYDEKGFCMR

RBM26

291

Q5T8P6
GCNRKIKDRYLLKAL

LMO1

26

P25800
FGCCKRRAELYRRKD

LHCGR

641

P22888
ERLHKCRLCYKQLKS

KATNB1

611

Q9BVA0
KRYGRCKRDCLESEK

DEFB114

31

Q30KQ6
RDDPCKQCRKRYEKG

FBXO46

526

Q6PJ61
KQCRKRYEKGDVSLC

FBXO46

531

Q6PJ61
KERRRKLNLCLYCGT

PEG10

286

Q86TG7
KGCAGCNRKIKDRYL

LMO3

11

Q8TAP4
DKIRRKNCPACRYRK

NR3C1

466

P04150
VDKDKRNQCRYCRLR

HNF4G

56

Q14541
NGCYLRRQKRFKCEK

FOXA1

256

P55317
CCRRKRGFRIQFQKK

IGSF5

306

Q9NSI5
KNKFRCDSGRCIARK

C6

141

P13671
IIFCCRKKRREEKYE

CXADR

256

P78310
KECRRRKKEYVKCLE

CREM

301

Q03060
QGLKDEVLYKCRKCR

DUSP12

211

Q9UNI6
RLKLVYDKCDRSCKI

PPARA

131

Q07869
GCYLRRQKRFKCEKQ

FOXA2

246

Q9Y261
VKKGCPRCARRRKYQ

PLEKHM1

1036

Q9Y4G2
VLKKRCKDCYLVKRR

MRPL36

71

Q9P0J6
VDCSLCGKKRRYVRL

SPDYA

226

Q5MJ70
ERQYRKKCAKCGLPL

STEEP1

86

Q9H5V9
AKFLKKRRRGQDCRA

STK17B

61

O94768
RYNLKQRKPKVLECC

RNF182

26

Q8N6D2
RYKQRCAELKKALCT

ZC3HC1

136

Q86WB0
SKCEDCGKRYKRRLN

ZNF223

456

Q9UK11
CCRKLKLPDLKRNDY

TRPM6

1971

Q9BX84
RLGEKLYECSECRKR

ZNF84

201

P51523
KCEDCGKRYKRRLNL

ZNF225

681

Q9UK10
NSSKCEDCGKRYKRR

ZNF230

446

Q9UIE0
HRRKKLYKCEECGKA

ZNF726P1

96

Q15940
KCEDCGKRYKRRLNL

ZNF222

426

Q9UK12
KDLPFRCKRCRKGFR

ZFY

711

P08048
KRCLGRREYVKKRQA

MYO1H

716

Q8N1T3