Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionribonuclease III activity

DROSHA DICER1

1.92e-053512GO:0004525
GeneOntologyMolecularFunctiondouble-stranded RNA-specific ribonuclease activity

DROSHA DICER1

1.92e-053512GO:0032296
GeneOntologyBiologicalProcesstrachea development

RARG MAPK1 HYDIN

2.12e-0522513GO:0060438
MousePhenoincreased circulating interleukin-13 level

IRF1 NLRP3

5.79e-054442MP:0008608
MousePhenoabnormal circulating interleukin-3 level

IRF1 NLRP3

9.62e-055442MP:0008622
MousePhenoincreased circulating interleukin-3 level

IRF1 NLRP3

9.62e-055442MP:0008623
DomainRibonuclease_3

DROSHA DICER1

1.94e-053482PF00636
DomainRIBOc

DROSHA DICER1

1.94e-053482SM00535
DomainRNase_III_dom

DROSHA DICER1

1.94e-053482IPR000999
DomainRNASE_3_1

DROSHA DICER1

1.94e-053482PS00517
DomainRNASE_3_2

DROSHA DICER1

1.94e-053482PS50142
Domain-

DROSHA DICER1

1.94e-0534821.10.1520.10
DomainMyosin_tail_1

CGN CGNL1

9.64e-0418482PF01576
DomainMyosin_tail

CGN CGNL1

9.64e-0418482IPR002928
DomainDSRM

DROSHA DICER1

1.08e-0319482SM00358
Domaindsrm

DROSHA DICER1

1.19e-0320482PF00035
DomainDS_RBD

DROSHA DICER1

1.32e-0321482PS50137
DomainSANT_dom

MIER3 SMARCC1

2.02e-0326482IPR017884
Domain-

DROSHA DICER1

2.18e-03274823.30.160.20
DomaindsRBD_dom

DROSHA DICER1

2.34e-0328482IPR014720
DomainSANT

MIER3 SMARCC1

2.34e-0328482PS51293
DomainMyb_DNA-binding

MIER3 SMARCC1

3.65e-0335482PF00249
DomainBROMODOMAIN_1

BRD8 CECR2

4.07e-0337482PS00633
DomainBromodomain

BRD8 CECR2

4.29e-0338482PF00439
DomainBROMODOMAIN_2

BRD8 CECR2

4.98e-0341482PS50014
DomainBROMO

BRD8 CECR2

5.22e-0342482SM00297
DomainBromodomain

BRD8 CECR2

5.22e-0342482IPR001487
Domain-

BRD8 CECR2

5.22e-03424821.20.920.10
DomainSANT

MIER3 SMARCC1

7.32e-0350482SM00717
PathwayWP_EXRNA_MECHANISM_OF_ACTION_AND_BIOGENESIS

DROSHA DICER1

8.93e-056352M39578
PathwayWP_MIRNA_BIOGENESIS

DROSHA DICER1

8.93e-056352M39416
Pubmed

A human MAP kinase interactome.

RIF1 ANK3 DAB2 DIAPH2 EVPL AKAP13 CGNL1 MAPK1 HSP90AB1

4.85e-0848653920936779
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

BICD2 RIF1 BRD8 LMO7 GTSE1 DAB2 AKAP13 IPO4 HSP90AB1

6.50e-0850353916964243
Pubmed

Stress induces p38 MAPK-mediated phosphorylation and inhibition of Drosha-dependent cell survival.

DROSHA MAPK1

2.28e-06253225699712
Pubmed

Sperm-borne miRNAs and endo-siRNAs are important for fertilization and preimplantation embryonic development.

DROSHA DICER1

2.28e-06253226718009
Pubmed

DICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors.

DROSHA DICER1

2.28e-06253226906421
Pubmed

Impact of DICER1 and DROSHA on the Angiogenic Capacity of Human Endothelial Cells.

DROSHA DICER1

2.28e-06253234576018
Pubmed

Knock-down of core proteins regulating microRNA biogenesis has no effect on sensitivity of lung cancer cells to ionizing radiation.

DROSHA DICER1

2.28e-06253222479364
Pubmed

Upregulation of microRNA processing enzymes Drosha and Dicer in gestational diabetes mellitus.

DROSHA DICER1

2.28e-06253225295740
Pubmed

Evaluating the Effect of 3'-UTR Variants in DICER1 and DROSHA on Their Tissue-Specific Expression by miRNA Target Prediction.

DROSHA DICER1

2.28e-06253234287278
Pubmed

Differences in the Drosha and Dicer Cleavage Profiles in Colorectal Cancer and Normal Colon Tissue Samples.

DROSHA DICER1

2.28e-06253232894467
Pubmed

The effects of DICER1 and DROSHA polymorphisms on susceptibility to recurrent spontaneous abortion.

DROSHA DICER1

2.28e-06253231659796
Pubmed

Dicer, Drosha, and outcomes in patients with ovarian cancer.

DROSHA DICER1

2.28e-06253219092150
Pubmed

Dysregulated expression of dicer and drosha in breast cancer.

DROSHA DICER1

2.28e-06253221898071
Pubmed

The expression of Dicer and Drosha in matched normal tissues, tumours and lymph node metastases in triple negative breast cancer.

DROSHA DICER1

2.28e-06253224725360
Pubmed

Expression of DROSHA and DICER genes in peripheral blood leukocytes in lung sarcoidosis.

DROSHA DICER1

2.28e-06253230701851
Pubmed

siRNA release from pri-miRNA scaffolds is controlled by the sequence and structure of RNA.

DROSHA DICER1

2.28e-06253226921501
Pubmed

Alternative initiation and splicing in dicer gene expression in human breast cells.

DROSHA DICER1

2.28e-06253215987463
Pubmed

Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus.

DROSHA DICER1

2.28e-06253218434510
Pubmed

Perturbation of DROSHA and DICER expression by human papillomavirus 16 oncoproteins.

DROSHA DICER1

2.28e-06253228448850
Pubmed

Dicer and Drosha expression and response to Bevacizumab-based therapy in advanced colorectal cancer patients.

DROSHA DICER1

2.28e-06253223266047
Pubmed

JACOP, a novel plaque protein localizing at the apical junctional complex with sequence similarity to cingulin.

CGN CGNL1

2.28e-06253215292197
Pubmed

Dicer regulates activation of the NLRP3 inflammasome.

DICER1 NLRP3

2.28e-06253231013297
Pubmed

DICER1, DROSHA and miRNAs in patients with non-small cell lung cancer: implications for outcomes and histologic classification.

DROSHA DICER1

2.28e-06253223349018
Pubmed

Sequence features of Drosha and Dicer cleavage sites affect the complexity of isomiRs.

DROSHA DICER1

2.28e-06253225867481
Pubmed

Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours.

DROSHA DICER1

2.28e-06253225190313
Pubmed

DICER and DROSHA gene expression and polymorphisms in autoimmune thyroid diseases.

DROSHA DICER1

2.28e-06253227808570
Pubmed

Expression levels of the microRNA processing enzymes Drosha and dicer in epithelial skin cancer.

DROSHA DICER1

2.28e-06253220210522
Pubmed

Murine follicular development requires oocyte DICER, but not DROSHA.

DROSHA DICER1

2.28e-06253224990804
Pubmed

DROSHA rs10719 and DICER1 rs3742330 polymorphisms in endometriosis and different diseases: Case-control and review studies.

DROSHA DICER1

2.28e-06253233535080
Pubmed

The 3' UTR polymorphisms rs3742330 in DICER1 and rs10719 in DROSHA genes are not associated with primary open-angle and angle-closure glaucoma: As case-control study.

DROSHA DICER1

2.28e-06253237099569
Pubmed

The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy.

DROSHA DICER1

2.28e-06253221544061
Pubmed

Mosaic variegated aneuploidy in mouse BubR1 deficient embryos and pregnancy loss in human.

BUB1B MAPK1

2.28e-06253224981203
Pubmed

Major regulators of microRNAs biogenesis Dicer and Drosha are down-regulated in endometrial cancer.

DROSHA DICER1

2.28e-06253221559780
Pubmed

Dynamic microRNA gene transcription and processing during T cell development.

DROSHA DICER1

2.28e-06253222379031
Pubmed

HSP90β controls NLRP3 autoactivation.

NLRP3 HSP90AB1

2.28e-06253238416826
Pubmed

High copy number variation of cancer-related microRNA genes and frequent amplification of DICER1 and DROSHA in lung cancer.

DROSHA DICER1

2.28e-06253226156018
Pubmed

A role for Dicer in immune regulation.

DROSHA DICER1

2.28e-06253217060477
Pubmed

Association of rs1057035polymorphism in microRNA biogenesis pathway gene (DICER1) with azoospermia among Iranian population.

DROSHA DICER1

2.28e-06253229892896
Pubmed

Genetic variants in microRNA biogenesis pathway genes are associated with semen quality in a Han-Chinese population.

DROSHA DICER1

2.28e-06253222381205
Pubmed

microRNA signature and expression of Dicer and Drosha can predict prognosis and delineate risk groups in neuroblastoma.

DROSHA DICER1

2.28e-06253220805302
Pubmed

The microRNA-processing enzymes: Drosha and Dicer can predict prognosis of nasopharyngeal carcinoma.

DROSHA DICER1

2.28e-06253221953080
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

BICD2 RIF1 BRD8 LMO7 GTSE1 DAB2 SMARCC1 OGA HSP90AB1

2.36e-0677453915302935
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

RIF1 BRD8 UBE2Q1 LMO7 BUB1B DDX23 SNUPN HSP90AB1

2.68e-0658253820467437
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RIF1 RNH1 CGN SMARCC1 DDX23 FRYL IPO4 DICER1

6.23e-0665353822586326
Pubmed

Overexpression of microRNA biogenesis machinery: Drosha, DGCR8 and Dicer in multiple sclerosis patients.

DROSHA DICER1

6.83e-06353225439752
Pubmed

MicroRNA binding to the HIV-1 Gag protein inhibits Gag assembly and virus production.

DROSHA DICER1

6.83e-06353224938790
Pubmed

ERK1/2 activation is a therapeutic target in age-related macular degeneration.

MAPK1 DICER1

6.83e-06353222869729
Pubmed

EIF2C, Dicer, and Drosha are up-regulated along tumor progression and associated with poor prognosis in bladder carcinoma.

DROSHA DICER1

6.83e-06353225656609
Pubmed

Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs.

DROSHA DICER1

6.83e-06353222706270
Pubmed

Association between Genetic Polymorphisms in microRNA Machinery Genes and Risk of Papillary Thyroid Carcinoma.

DROSHA DICER1

6.83e-06353231250375
Pubmed

Genetic variants in microRNA machinery genes are associated [corrected] with idiopathic recurrent pregnancy loss risk.

DROSHA DICER1

6.83e-06353224769857
Pubmed

Restoration of IRF1-dependent anticancer effects by MEK inhibition in human cancer cells.

IRF1 MAPK1

6.83e-06353225497010
Pubmed

Immunohistochemical analysis of the endoribonucleases Drosha, Dicer and Ago2 in smooth muscle tumours of soft tissues.

DROSHA DICER1

6.83e-06353222394132
Pubmed

The RNase III enzyme DROSHA is essential for microRNA production and spermatogenesis.

DROSHA DICER1

6.83e-06353222665486
Pubmed

Re-evaluation of the roles of DROSHA, Export in 5, and DICER in microRNA biogenesis.

DROSHA DICER1

6.83e-06353226976605
Pubmed

The miRNA biogenesis pathway prevents inappropriate expression of injury response genes in developing and adult Schwann cells.

DROSHA DICER1

6.83e-06353230295958
Pubmed

Drosha controls dendritic cell development by cleaving messenger RNAs encoding inhibitors of myelopoiesis.

DROSHA DICER1

6.83e-06353226437240
Pubmed

Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin.

DROSHA DICER1

6.83e-06353222434867
Pubmed

Complexity in regulation of microRNA machinery components in invasive breast carcinoma.

DROSHA DICER1

6.83e-06353224574065
Pubmed

Impaired expression of DICER, DROSHA, SBDS and some microRNAs in mesenchymal stromal cells from myelodysplastic syndrome patients.

DROSHA DICER1

6.83e-06353222371183
Pubmed

Expression of the microRNA regulators Drosha, Dicer and Ago2 in non-small cell lung carcinomas.

DROSHA DICER1

6.83e-06353226227789
Pubmed

Pineoblastoma is uniquely tolerant of mutually exclusive loss of DICER1, DROSHA or DGCR8.

DROSHA DICER1

6.83e-06353232124011
Pubmed

Canonical and alternate functions of the microRNA biogenesis machinery.

DROSHA DICER1

6.83e-06353220713509
Pubmed

Investigation of AID, Dicer, and Drosha Expressions in Patients with Chronic Lymphocytic Leukemia.

DROSHA DICER1

6.83e-06353228388279
Pubmed

Drosha, DGCR8, and Dicer mRNAs are down-regulated in human cells infected with dengue virus 4, and play a role in viral pathogenesis.

DROSHA DICER1

6.83e-06353227173348
Pubmed

Inducing cell proliferation inhibition and apoptosis via silencing Dicer, Drosha, and Exportin 5 in urothelial carcinoma of the bladder.

DROSHA DICER1

6.83e-06353222766726
Pubmed

The impact of Dicer, Drosha, and Exportin-5 levels in polycystic ovary syndrome (PCOS) diagnosis and phenotyping.

DROSHA DICER1

6.83e-06353234855193
Pubmed

Male germ cells express abundant endogenous siRNAs.

DROSHA DICER1

6.83e-06353221788498
Pubmed

Expression of the ribonucleases Drosha, Dicer, and Ago2 in colorectal carcinomas.

DROSHA DICER1

6.83e-06353221769619
Pubmed

Quercetin negatively regulates IL-1β production in Pseudomonas aeruginosa-infected human macrophages through the inhibition of MAPK/NLRP3 inflammasome pathways.

MAPK1 NLRP3

6.83e-06353232817626
Pubmed

MgcRacGAP interacts with cingulin and paracingulin to regulate Rac1 activation and development of the tight junction barrier during epithelial junction assembly.

CGN CGNL1

6.83e-06353224807907
Pubmed

Transcript Level of MicroRNA Processing Elements in Gastric Cancer.

DROSHA DICER1

6.83e-06353230168106
Pubmed

Expression of genes for microRNA-processing enzymes is altered in advanced non-alcoholic fatty liver disease.

DROSHA DICER1

6.83e-06353223663110
Pubmed

Tagging genes with cassette-exchange sites.

RIF1 RARG DROSHA GTSE1 SMARCC1 AKAP13

1.20e-0533553615741177
Pubmed

Dicer and Drosha expression in patients with nephrotic syndrome.

DROSHA DICER1

1.36e-05453232412691
Pubmed

Argonaute, Dicer, and Drosha are up-regulated along tumor progression in serous ovarian carcinoma.

DROSHA DICER1

1.36e-05453222647351
Pubmed

Hsp90·Cdc37 Complexes with Protein Kinases Form Cooperatively with Multiple Distinct Interaction Sites.

MAPK1 HSP90AB1

1.36e-05453226511315
Pubmed

Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis.

DROSHA DICER1

1.36e-05453220699384
Pubmed

PTEN modulates miR-21 processing via RNA-regulatory protein RNH1.

RNH1 DROSHA

1.36e-05453222162762
Pubmed

Ars2 maintains neural stem-cell identity through direct transcriptional activation of Sox2.

DROSHA DICER1

1.36e-05453222198669
Pubmed

Pathologically high intraocular pressure induces mitochondrial dysfunction through Drp1 and leads to retinal ganglion cell PANoptosis in glaucoma.

MAPK1 NLRP3

1.36e-05453236989574
Pubmed

3'-UTR Polymorphisms in the MiRNA Machinery Genes DROSHA, DICER1, RAN, and XPO5 Are Associated with Colorectal Cancer Risk in a Korean Population.

DROSHA DICER1

1.36e-05453226147304
Pubmed

Multipotency of Adult Hippocampal NSCs In Vivo Is Restricted by Drosha/NFIB.

DROSHA DICER1

1.36e-05453227545503
Pubmed

Analysis of microRNA processing machinery gene (DROSHA, DICER1, RAN, and XPO5) variants association with end-stage renal disease.

DROSHA DICER1

1.36e-05453232770606
Pubmed

A-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in α1-adrenergic receptor-induced p38 activation.

AKAP13 MAPK1

2.27e-05553221224381
Pubmed

miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation.

DROSHA DICER1

2.27e-05553227880903
Pubmed

Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts.

IRF1 NLRP3

2.27e-05553220031576
Pubmed

The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease.

DROSHA DICER1

2.27e-05553218725527
Pubmed

BRG1 and SMARCAL1 transcriptionally co-regulate DROSHA, DGCR8 and DICER in response to doxorubicin-induced DNA damage.

DROSHA DICER1

2.27e-05553228716689
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

RIF1 CLGN BBX ANK3 RNH1 LMO7 CGN IPO4 DICER1 EHD3

2.66e-051321531027173435
Pubmed

New mitochondrial DNA synthesis enables NLRP3 inflammasome activation.

IRF1 NLRP3

3.40e-05653230046112
Pubmed

Upregulation of Cyclin B1 by miRNA and its implications in cancer.

DROSHA DICER1

3.40e-05653222053081
Pubmed

IRF1 Is a Transcriptional Regulator of ZBP1 Promoting NLRP3 Inflammasome Activation and Cell Death during Influenza Virus Infection.

IRF1 NLRP3

3.40e-05653229321274
Pubmed

Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine platelets.

DROSHA DICER1

3.40e-05653226773046
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

RHBDL2 BRD8 ANK3 UBE2Q1 SMARCC1 FRYL MAPK1 DSE EHD3

3.47e-05108453911544199
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

LMO7 CGN AKAP13 FRYL HSP90AB1

4.39e-0525553515324660
Pubmed

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

RIF1 SMARCC1 FRYL MAPK1

4.59e-0512953423022380
Pubmed

An interaction network predicted from public data as a discovery tool: application to the Hsp90 molecular chaperone machine.

IPO4 HSP90AB1

4.76e-05753222022502
Pubmed

P38MAPK-dependent phosphorylation and degradation of SRC-3/AIB1 and RARalpha-mediated transcription.

RARG MAPK1

6.34e-05853216456540
Pubmed

Black carbon exposures, blood pressure, and interactions with single nucleotide polymorphisms in MicroRNA processing genes.

DROSHA DICER1

6.34e-05853220211803
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TRPM3 GTSE1 CGN BUB1B PDCL2 PLS1

1.15e-07194536c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRPM3 LMO7 CECR2 AKAP13 CGNL1

2.19e-06177535b7fee75de7e96924af488a5baa2334711889ae7c
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRPM3 LMO7 CECR2 CGN CGNL1

2.32e-0617953504ce3673e46606f63d9c87bcba3a64c96817d812
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRPM3 LMO7 CECR2 CGN CGNL1

2.80e-061865354e94158db52df41d71e67b02b9895a358eebee0f
ToppCelldroplet-Thymus-nan-18m-Myeloid-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3F ANK3 CGN CGNL1 HYDIN

2.87e-06187535ed69e7cbd6fb59363b0e26f24887fc49405397ce
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRPM3 LMO7 CECR2 CGN CGNL1

2.87e-0618753558d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

ANK3 TRPM3 LMO7 TCEAL4 HSP90AB1

3.89e-061995351b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

ANK3 TRPM3 LMO7 TCEAL4 HSP90AB1

3.89e-061995354bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial-AT1_-_meso|PND01-03-samps / Age Group, Lineage, Cell class and subclass

LMO7 CGN EVPL PLS1

3.06e-051505346a13e4c4b9c9e54a5016573a37132465ec1c8f99
ToppCell390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CLGN GTSE1 CGN BUB1B

4.23e-05163534aa5ea367f787c1543afb7eb80a801432e1c44011
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

AKAP13 MAPK1 DSE NLRP3

5.10e-05171534bdd30100b74e012eec3090799c22635aa57fa91d
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|367C / Donor, Lineage, Cell class and subclass (all cells)

CGN BUB1B EVPL PLS1

5.22e-05172534a9e65201ad9ab4f64251aba2c0bb3d8f9e0193b6
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|367C / Donor, Lineage, Cell class and subclass (all cells)

CGN BUB1B EVPL PLS1

5.22e-0517253426006967d0c82f7bd9b36a18e97a1b93e856aa67
ToppCelldroplet-Lung-LUNG-30m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRC7 ANK3 CECR2 HYDIN

5.71e-051765345201f003192c033655ba47f0faf8c47a96eae03d
ToppCell390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CLGN GTSE1 CGN BUB1B

5.71e-05176534941e8724b6f680719ef2a4f190f943b205bb9e78
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRPM3 LMO7 CECR2 CGNL1

5.83e-051775349af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO7 DIAPH2 DDX23 HSP90AB1

5.96e-0517853401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANK3 LMO7 CGNL1 PLS1

6.09e-05179534cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRPM3 LMO7 CECR2 CGNL1

6.36e-05181534b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellControl-Classical_Monocyte-cMono_4|Control / Disease condition and Cell class

IRF1 ELF4 DSE NLRP3

6.36e-05181534f3e1d8fe5cf1eba19e51c3680a55306cae687fe9
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

RARG GTSE1 BUB1B ELF4

6.64e-0518353454782c2e23bbeca5b683aa931393b1118da4aa37
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRPM3 LMO7 CECR2 CGNL1

6.64e-05183534ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM3 GTSE1 BUB1B DAB2

6.64e-05183534e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRPM3 LMO7 CECR2 CGNL1

6.78e-0518453442ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LMO7 CGN PDCL2 CGNL1

6.78e-0518453429c95b814a0b1ad8734ed68b77df29c08594e5ec
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 TRPM3 LMO7 CECR2

6.92e-051855340d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CECR2 CGN EVPL PLS1

6.92e-05185534636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRPM3 LMO7 CECR2 CGNL1

6.92e-05185534c82eab551f65ecebe6db908eda9f9eb3414693c7
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRPM3 LMO7 CECR2 CGNL1

7.07e-051865343aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellLPS-antiTNF-Epithelial_alveolar|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 TRPM3 LMO7 CECR2

7.22e-05187534201ff693e4756ee3e44762885b3a303a77eb535b
ToppCellLPS_only-Epithelial_alveolar-AT_1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRPM3 LMO7 CGN CGNL1

7.22e-05187534ff26a533d310126521efe1d05cf8b9d32e524550
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 TRPM3 LMO7 CECR2

7.37e-0518853443a0508d2524a5b310e89e9422843dcaab999bc3
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ANK3 LMO7 CGN PLS1

7.52e-051895347659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LMO7 GTSE1 CGN PLS1

7.52e-05189534c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCell367C-Epithelial_cells|367C / Donor, Lineage, Cell class and subclass (all cells)

ANK3 LMO7 CGN PLS1

7.83e-05191534d31975fc33779b0b3ff1a50d7c64fec8d08be4d4
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANK3 LMO7 CECR2 CGNL1

7.83e-05191534e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

ANK3 LMO7 CECR2 CGNL1

7.99e-05192534499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellE15.5-Epithelial|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ANK3 LMO7 CGN HSP90AB1

7.99e-051925343f2ecd428c0c608d7bbd7b403a07399b87761338
ToppCellCOPD-Epithelial|COPD / Disease state, Lineage and Cell class

ANK3 LMO7 CGN HYDIN

7.99e-051925340644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RARG DAB2 DSE EHD3

7.99e-051925342bfac6b3956265205ca47d06888851ed68b65999
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK3 LMO7 AKAP13 CGNL1

7.99e-0519253429f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3F RIF1 HYDIN EHD3

7.99e-051925341ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RARG DAB2 DSE EHD3

7.99e-05192534d525f7f088a53110912600a7c9f6d33b9270d534
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 TRPM3 LMO7 CGNL1

8.15e-051935343866667dd221612589ae50f5c52f73a183a49ce6
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BICD2 DAB2 DSE EHD3

8.32e-05194534c8b9551b93a5aed62154b487db90130604a6125c
ToppCellControl-Epithelial|Control / Disease state, Lineage and Cell class

ANK3 LMO7 CGN CGNL1

8.49e-051955341798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANK3 LMO7 CECR2 CCER2

8.65e-05196534ed76eeb37400ca154feae9b7ebaddb6c434f8b81
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK3 CECR2 AKAP13 CGNL1

8.65e-051965347e5addaa844e66f8160e05858c341866a80aed23
ToppCellPCW_10-12-Epithelial|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LMO7 CGN EVPL PLS1

8.65e-051965349bfb31ff3e4f2c0a9405c418c86bfec5dbca23e2
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3F RARG DAB2 EHD3

8.65e-0519653481900dcc9451ff6606ec940c16b559d73247590e
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANK3 CECR2 AKAP13 CGNL1

8.83e-05197534bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCellAT1-AT2_cells|World / lung cells shred on cell class, cell subclass, sample id

LMO7 CGN EVPL CGNL1

9.00e-05198534a5b3617ea2ed4bffba59edcf6284799c2b3bbb29
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-AT1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LMO7 CGN EVPL CGNL1

9.00e-0519853454228dd9a50616d2022712d162a419ed0327cabd
ToppCellPCW_13-14-Epithelial|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LMO7 CGN EVPL PLS1

9.00e-0519853448eb6f69a464a34ab32e8d425a22b9d45ec20428
ToppCell3'-Adult-Distal_Rectal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RHBDL2 LMO7 DAB2 AKAP13

9.00e-051985347ad7726fc405806b1d7824f58548073ea5e0c70b
ToppCell3'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell-TA|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RHBDL2 LMO7 DAB2 AKAP13

9.00e-051985341fbec311f2c987ca90a023a5989128c05aa12d5c
ToppCellHealthy_Control-Myeloid-Macrophages-FCN1+SPP1+|Healthy_Control / Condition, Lineage, Cell class and cell subclass

RIF1 CLGN IRF1 DSE

9.00e-05198534aa90326b82e21de37af5642df6a70a8b21af7f04
ToppCell3'-Adult-Distal_Rectal-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RHBDL2 LMO7 DAB2 AKAP13

9.00e-05198534ceede961ad9af6a3159db7efaa5087bf38aafc2d
ToppCell3'-Adult-Distal_Rectal-Epithelial-epithelial_progenitor_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RHBDL2 LMO7 DAB2 AKAP13

9.00e-051985344f26a60e99f42343e5af7221723e108a1a1b7827
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANK3 LMO7 CECR2 CGNL1

9.18e-051995345f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANK3 LMO7 CECR2 CGNL1

9.18e-051995348587bd98de7767a575088afbea07a1feb4516b9b
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar-AT1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LMO7 CGN EVPL CGNL1

9.18e-05199534aca81a879ef9c196bd1885eff4c63ffe6c9682b7
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal-Cilia-bearing_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

TRPM3 DAB2 CGNL1 HYDIN

9.18e-051995342d8ab4aee300c7c4baf662940ce855da2b6d2cae
ToppCellBronchial-10x5prime-Epithelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ANK3 LMO7 CGN PLS1

9.36e-05200534d3ee5f79513e2ac02ad3329b59e6290d457c44d2
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ANK3 LMO7 CGN EVPL

9.36e-0520053497f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

TRPM3 LMO7 CECR2 CGNL1

9.36e-052005342dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellBiopsy_Other_PF-Epithelial-Transitional_AT2|Biopsy_Other_PF / Sample group, Lineage and Cell type

LMO7 CGN EVPL CGNL1

9.36e-052005341ba6327851aa61e9a1f1fe1671bc27929d93ac74
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Mesenchymal-Cilia-bearing_cell|3m / Sample Type, Dataset, Time_group, and Cell type.

TRPM3 DAB2 CGNL1 HYDIN

9.36e-052005340d14a950172a56b11fdebee8f4e13b0c10e0d592
ToppCelldistal-2-Epithelial|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ANK3 LMO7 CGN HYDIN

9.36e-052005342fc1e95706f212bf18ecdf6eb5b3182ac98c9b52
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Mesenchymal-Cilia-bearing_cell|2m / Sample Type, Dataset, Time_group, and Cell type.

TRPM3 DAB2 CGNL1 HYDIN

9.36e-05200534c6060205cab46628d845edbf17e2c5be7508181c
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ANK3 LMO7 CGN EVPL

9.36e-05200534ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal|6m / Sample Type, Dataset, Time_group, and Cell type.

TRPM3 LMO7 CGNL1 HYDIN

9.36e-0520053413ec8afea86e4a10599c924871ba4e325b0a8013
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LMO7 CECR2 CGNL1

4.97e-041305336434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCellControl-Classical_Monocyte-|Control / Disease condition and Cell class

CLGN BUB1B NLRP3

4.97e-04130533e55f522dab5a6c3af30ad87ac8b32166f660c314
ToppCellControl-Classical_Monocyte-|Classical_Monocyte / Disease condition and Cell class

CLGN BUB1B NLRP3

4.97e-041305334433b40b099845f113993b6ecf85ec594b4b9219
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DRC7 PLS1 HYDIN

6.69e-0414453308005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor|bone_marrow / Manually curated celltypes from each tissue

GTSE1 BUB1B CCER2

6.96e-04146533035393166f3ad5ab95602a8ae11b7d0ee4b1d691
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DRC7 GTSE1 BUB1B

7.24e-0414853318cfecd6ae20edb74f5d44ba759909df356acf3a
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DRC7 PDCL2 HYDIN

8.13e-041545334e3bc24043144143842627cacf6f90dda2228910
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DRC7 PDCL2 HYDIN

8.13e-041545337556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GTSE1 MIER3 PLS1

8.43e-04156533d411116d54add2d4fe649a97ac54cb94c085312f
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ZSCAN12 TRPM3 EVPL

8.59e-041575336a0aa66964eecbbc232abf1d2e6c8422e4ce69d0
ToppCellfacs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l8|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CECR2 GTSE1 NLRP3

8.59e-041575335098675f64342c41c5ca3551b24962d10c83e64d
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AKAP13 DSE NLRP3

9.07e-041605336ed37d1fd0304932319d6b942502404115ff36a7
ToppCellLeuk-UTI-Myeloid-tDC|Leuk-UTI / Disease, Lineage and Cell Type

CLGN BBX DAB2

9.24e-0416153351b9f60986ed2e8e2297d31c80462c3ab65a2e5e
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Hippocampus / BrainAtlas - Mouse McCarroll V32

SEMA3F EVPL CCER2

9.24e-0416153366554f59eaea4ba55a6c6724f9368e24e99c91e9
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

CGNL1 CCER2 PLS1

9.41e-041625332259e9536147e9cdee772e3a30ba7d104573262c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DRC7 ANK3 CCER2

9.41e-0416253380317c4253bf8e897782e562f29835f181c65b98
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDCL2 IPO4 PLS1

9.57e-04163533360cd65decda24853124f33a174f5224d7f3ce23
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

ANK3 LMO7 AKAP13

9.57e-04163533e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDCL2 IPO4 PLS1

9.57e-04163533b59d9b4f7c9f4e5e2c7783a49a96729dae3a81e5
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

ANK3 LMO7 AKAP13

9.74e-04164533beaa13a75c3bb72446c85084d75e9fe3f15fd3d4
ToppCell343B-Epithelial_cells-Epithelial-A_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

ANK3 LMO7 AKAP13

9.74e-04164533d005cfd821b87548b075120bffe65a0be9860463
ToppCellPBMC-Mild-Hematopoietic-Platelet-Platelet-plt_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DRC7 DAB2 EHD3

9.92e-041655336799a6580c667738995cceb31cbf1c7fbdc4ff84
ToppCellPBMC-Mild-Hematopoietic-Platelet-Platelet-plt_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DRC7 DAB2 EHD3

9.92e-041655338329d780f244bc31344443b29e5a00529a016662
ToppCellfacs-Heart-LV-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTSE1 BUB1B NLRP3

9.92e-0416553384eca6a0f5e996b6955ae79fa102af239098fe8f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZSCAN12 TRPM3 GTSE1

9.92e-04165533e2aebb2fe197151e019371b8960f76f0c2386f08
ToppCellfacs-Heart-LV-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GTSE1 BUB1B NLRP3

9.92e-04165533af59a095ecc6758abc13d763c00e44447c488167
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZSCAN12 TRPM3 GTSE1

9.92e-04165533b087771499aeb31cc4a338d2d0a9392a4ec1ac45
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZSCAN12 TRPM3 GTSE1

9.92e-04165533d8f8b088fd28a6b9dbd6b51bcaee42000e963321
DrugEtifenin [63245-28-3]; Down 200; 12.4uM; PC3; HT_HG-U133A

BICD2 BBX GTSE1 SMARCC1 AKAP13 DICER1

3.17e-061785263998_DN
DrugNeostigmine bromide [114-80-7]; Down 200; 13.2uM; PC3; HT_HG-U133A

BICD2 BBX GTSE1 DAB2 SMARCC1 DICER1

4.34e-061885266735_DN
DiseaseRhabdomyosarcoma

BUB1B DICER1

2.91e-0415502C0035412
Diseaseneutrophil count

BICD2 BBX UBE2Q1 CGN IRF1 AKAP13 HYDIN NLRP3 EHD3

4.66e-041382509EFO_0004833
DiseaseAnhedonia

ANK3 MAPK1

7.58e-0424502C0178417
DiseaseLung Neoplasms

ANK3 SMARCC1 IRF1 MAPK1

1.06e-03265504C0024121
DiseaseMalignant neoplasm of lung

ANK3 SMARCC1 IRF1 MAPK1

1.07e-03266504C0242379
Diseasecancer (implicated_via_orthology)

HSP90AB4P SMARCC1 MAPK1 HSP90AB1

1.10e-03268504DOID:162 (implicated_via_orthology)
DiseaseBilateral Wilms Tumor

DROSHA DICER1

1.11e-0329502C2930471
Diseasemuscular atrophy (biomarker_via_orthology)

HSP90AB4P HSP90AB1

1.11e-0329502DOID:767 (biomarker_via_orthology)
Diseasemean platelet volume

SEMA3F BRD8 BBX TRPM3 FRYL DSE EHD3

1.58e-031020507EFO_0004584
DiseaseNephroblastoma

DROSHA DICER1

1.71e-0336502C0027708

Protein segments in the cluster

PeptideGeneStartEntry
EDRPMPKLEIEKEIE

BUB1B

746

O60566
MEDPKEIRKEELEED

BBX

386

Q8WY36
LGPAVDKDKEALMEE

BICD2

661

Q8TD16
PSIDGKEELDLAEKM

BRD8

386

Q9H0E9
EGIPSENEEEKKMLD

AKAP13

2341

Q12802
MLPDLKEKENDELDI

DIAPH2

361

O60879
EEKEEDIEVPKAMGD

DICER1

1796

Q9UPY3
EKLDESMERPESPKE

CECR2

1301

Q9BXF3
RMDLEEPEKVDKLQE

RARG

341

P13631
DEDEEGKLPEDIMKL

IRF1

226

P10914
EVMGEDIPEKIKDEV

C8orf76

316

Q96K31
DPLGDKEIKDVKEMF

DAB2

641

P98082
FDMELDDLPKEKLKE

MAPK1

331

P28482
LELPEDEEEKKKMEE

HSP90AB1

541

P08238
KEMPKDLVVIEDEDE

ELF4

291

Q99607
LPEDEEEKKIMEESN

HSP90AB4P

451

Q58FF6
EGVESDDLKKDLPLM

KIAA1109

1976

Q2LD37
PPKEESKDEIEEMVL

PDCL2

21

Q8N4E4
EGEELEELMKLSPEE

PLS1

256

Q14651
IMEEVVKLEKDPDLE

EVPL

1461

Q92817
EIPKGDDELAIDVMD

FRYL

721

O94915
EGELVLPDLEKDDMI

LMO7

556

Q8WWI1
KELPIDEDEEMKDLL

DSE

846

Q9UL01
EDLEKEGTMPLEDLL

MIER3

56

Q7Z3K6
DELPDMTLDKEEIAK

MIER3

96

Q7Z3K6
KPDTDEAEDPEKMLA

DDX23

576

Q9BUQ8
PGKLLPDEILEDDME

MEIOSIN

371

C9JSJ3
MDDPKKEDILLLADE

GTSE1

1

Q9NYZ3
ELEKGKMPIDLVIED

MEIS3P2

146

A8K0S8
PPSEDISLDEKKEME

HYDIN

2641

Q4G0P3
FLDLEDLDMDEEIKP

IFTAP

101

Q86VG3
KLPSKVLDDMDDDDD

CGNL1

1261

Q0VF96
EEEEKEERKRGPMET

CCER2

136

I3L3R5
IDLDELMKKDEPPLD

FAM172A

41

Q8WUF8
GMDEELDSPEELGKK

ANK3

1106

Q12955
EEERLMEAEKAKPDA

DRC7

281

Q8IY82
EEEELEIELMGETPK

IPO4

316

Q8TEX9
KMKPIEEGAEDDDDV

BVES

331

Q8NE79
NMPKEEEEEEKEGRH

NLRP3

686

Q96P20
MPDKNEEEEEELLKP

DROSHA

396

Q9NRR4
KEELEEEEKMREDGG

RHBDL2

21

Q9NX52
LPKDDQELEELMLEE

SEMA3F

496

Q13275
LTKEEEKKQPDEEPM

OGA

451

O60502
EEKPEETPKMELSLE

RIF1

1881

Q5UIP0
KDDEEMDIDTVKKLP

SNUPN

81

O95149
EKLEGAEEEKMEADP

SMARCC1

771

Q92922
KLADIDKDGMLDDDE

EHD3

486

Q9NZN3
KEEMEEELGEKIEVL

CGN

596

Q9P2M7
EKAALEKPMDLEEEK

CLGN

526

O14967
EEMLKDKGKPESEGE

TCEAL4

56

Q96EI5
EKPTKEKEEEDMELT

TRPM3

841

Q9HCF6
LEEKVEHLEEGPMIE

MRPL42

96

Q9Y6G3
EEMEDRLQALEKDKP

RNH1

441

P13489
EMEVEPARKGEEEQK

ZBTB17

221

Q13105
REVLGMEELEKLPEE

VRTN

366

Q9H8Y1
MDQDEPLEVKIEEEK

ZSCAN12

11

O43309
MKEEEPAEGKKSEDD

UBE2Q1

206

Q7Z7E8