Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN1B SCN3A SCN3B SCN7A

6.94e-0826314GO:0005248
GeneOntologyMolecularFunctionsodium channel activity

SCN1B SCN3A SCN3B SCN7A

1.22e-0652314GO:0005272
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity involved in cardiac muscle cell action potential

SCN1B SCN3B

3.49e-056312GO:0086006
GeneOntologyMolecularFunctionsodium channel inhibitor activity

SCN1B SCN3B

6.49e-058312GO:0019871
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SCN1B SCN3A SCN3B SCN7A

1.36e-04171314GO:0015081
GeneOntologyMolecularFunctiontransmembrane transporter binding

TRPC1 SCN1B SCN3B SCN7A

1.39e-04172314GO:0044325
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TRPC1 SCN1B SCN3A SCN3B SCN7A

1.71e-04343315GO:0005261
GeneOntologyMolecularFunctionsodium ion binding

SCN3A CAPN3

2.10e-0414312GO:0031402
GeneOntologyMolecularFunctionmonoatomic ion channel activity

TRPC1 SCN1B SCN3A SCN3B SCN7A

6.51e-04459315GO:0005216
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

TRPC1 SCN1B SCN3A SCN3B SCN7A

6.91e-04465315GO:0046873
GeneOntologyMolecularFunctionalkali metal ion binding

SCN3A CAPN3

7.41e-0426312GO:0031420
GeneOntologyMolecularFunctionfatty acyl-CoA hydrolase activity

ABCD1 HNF4A

7.99e-0427312GO:0047617
GeneOntologyMolecularFunctionacyl-CoA hydrolase activity

ABCD1 HNF4A

8.60e-0428312GO:0016289
GeneOntologyMolecularFunctionchannel activity

TRPC1 SCN1B SCN3A SCN3B SCN7A

1.19e-03525315GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

TRPC1 SCN1B SCN3A SCN3B SCN7A

1.20e-03526315GO:0022803
GeneOntologyMolecularFunctionsodium channel regulator activity

SCN1B SCN3B

2.12e-0344312GO:0017080
GeneOntologyMolecularFunctionthiolester hydrolase activity

ABCD1 HNF4A

2.41e-0347312GO:0016790
GeneOntologyMolecularFunctionion channel inhibitor activity

SCN1B SCN3B

2.52e-0348312GO:0008200
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

TRPC1 SCN1B SCN3A SCN3B SCN7A

2.59e-03627315GO:0022890
GeneOntologyMolecularFunctionchannel inhibitor activity

SCN1B SCN3B

2.73e-0350312GO:0016248
GeneOntologyMolecularFunctiontransporter inhibitor activity

SCN1B SCN3B

2.84e-0351312GO:0141110
GeneOntologyMolecularFunctiontransporter activity

ABCD1 XKR9 TRPC1 SCN1B SCN3A SCN3B SCN7A

3.07e-031289317GO:0005215
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

TRPC1 SCN1B SCN3A SCN3B SCN7A

3.32e-03664315GO:0008324
GeneOntologyMolecularFunctiontranscription corepressor binding

PER1 HNF4A

3.78e-0359312GO:0001222
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR8K1 KDR IL1RL1 TAS2R13 OPN4 ADGRV1 SCN7A

4.02e-031353317GO:0004888
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

TRPC1 SCN1B SCN3A SCN3B SCN7A

5.82e-03758315GO:0015318
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

TRPC1 SCN1B SCN3A SCN3B SCN7A

7.03e-03793315GO:0015075
GeneOntologyMolecularFunctiontransmembrane transporter activity

ABCD1 TRPC1 SCN1B SCN3A SCN3B SCN7A

8.66e-031180316GO:0022857
GeneOntologyBiologicalProcessmembrane depolarization

KDR ABCD1 SCN1B SCN3A SCN3B

1.13e-06121325GO:0051899
GeneOntologyBiologicalProcessregulation of membrane depolarization

KDR ABCD1 SCN1B SCN3B

2.34e-0661324GO:0003254
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN1B SCN3A SCN3B SCN7A

2.50e-0662324GO:0086002
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN1B SCN3A SCN3B SCN7A

9.70e-0687324GO:0086001
GeneOntologyBiologicalProcesscardiac muscle cell contraction

SCN1B SCN3A SCN3B SCN7A

1.26e-0593324GO:0086003
GeneOntologyBiologicalProcessresponse to pyrethroid

SCN1B SCN3A

1.40e-054322GO:0046684
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN1B SCN3A SCN3B

2.34e-0536323GO:0086010
GeneOntologyBiologicalProcessactin-mediated cell contraction

SCN1B SCN3A SCN3B SCN7A

4.31e-05127324GO:0070252
GeneOntologyBiologicalProcesssodium ion transport

PER1 SCN1B SCN3A SCN3B SCN7A

6.09e-05275325GO:0006814
GeneOntologyBiologicalProcessresponse to insecticide

SCN1B SCN3A

8.34e-059322GO:0017085
GeneOntologyBiologicalProcessheart contraction

TRPC1 SCN1B SCN3A SCN3B SCN7A

8.90e-05298325GO:0060047
GeneOntologyBiologicalProcessactin filament-based movement

SCN1B SCN3A SCN3B SCN7A

8.90e-05153324GO:0030048
GeneOntologyBiologicalProcessregulation of atrial cardiac muscle cell membrane depolarization

SCN1B SCN3B

1.04e-0410322GO:0060371
GeneOntologyBiologicalProcessheart process

TRPC1 SCN1B SCN3A SCN3B SCN7A

1.06e-04309325GO:0003015
GeneOntologyBiologicalProcesscardiac muscle contraction

SCN1B SCN3A SCN3B SCN7A

1.25e-04167324GO:0060048
GeneOntologyBiologicalProcessregulation of membrane potential

KDR ABCD1 SCN1B SCN3A SCN3B SCN7A

1.92e-04559326GO:0042391
GeneOntologyBiologicalProcessself proteolysis

ADGRV1 CAPN3

2.42e-0415322GO:0097264
GeneOntologyBiologicalProcessaction potential

SCN1B SCN3A SCN3B SCN7A

2.54e-04201324GO:0001508
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SCN1B SCN3A SCN3B SCN7A

2.90e-04208324GO:0035725
GeneOntologyBiologicalProcessstriated muscle contraction

SCN1B SCN3A SCN3B SCN7A

3.40e-04217324GO:0006941
GeneOntologyBiologicalProcessblood circulation

KDR TRPC1 SCN1B SCN3A SCN3B SCN7A

4.24e-04648326GO:0008015
GeneOntologyBiologicalProcesscardiac conduction

TRPC1 SCN1B SCN3B

4.95e-04100323GO:0061337
GeneOntologyBiologicalProcesschemical homeostasis

KDR XK ABCD1 HNF4A JAGN1 TRPC1 CAPN3 SCN7A

5.03e-041249328GO:0048878
GeneOntologyBiologicalProcessregulation of sodium ion transport

PER1 SCN1B SCN3B

5.10e-04101323GO:0002028
GeneOntologyBiologicalProcessmembrane depolarization during cardiac muscle cell action potential

SCN1B SCN3B

5.78e-0423322GO:0086012
GeneOntologyBiologicalProcessmetal ion transport

PER1 TRPC1 SCN1B SCN3A SCN3B CAPN3 SCN7A

7.15e-041000327GO:0030001
GeneOntologyBiologicalProcesspositive regulation of monoatomic ion transport

TRPC1 SCN1B SCN3B CAPN3

7.32e-04266324GO:0043270
GeneOntologyBiologicalProcessregulation of mitochondrial depolarization

KDR ABCD1

7.99e-0427322GO:0051900
GeneOntologyBiologicalProcesscirculatory system process

KDR TRPC1 SCN1B SCN3A SCN3B SCN7A

8.11e-04733326GO:0003013
GeneOntologyBiologicalProcessregulation of metal ion transport

PER1 TRPC1 SCN1B SCN3B CAPN3

9.03e-04493325GO:0010959
GeneOntologyBiologicalProcesspositive regulation of fatty acid biosynthetic process

ABCD1 HNF4A

9.22e-0429322GO:0045723
GeneOntologyBiologicalProcessregulation of circadian rhythm

PER1 OPN4 HNF4A

1.18e-03135323GO:0042752
GeneOntologyBiologicalProcesscell-cell signaling involved in cardiac conduction

SCN1B SCN3B

1.27e-0334322GO:0086019
GeneOntologyBiologicalProcessmitochondrial depolarization

KDR ABCD1

1.34e-0335322GO:0051882
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1B SCN3A SCN3B SCN7A

1.06e-0817324GO:0001518
GeneOntologyCellularComponentsodium channel complex

SCN1B SCN3A SCN3B SCN7A

1.05e-0729324GO:0034706
GeneOntologyCellularComponentcation channel complex

TRPC1 SCN1B SCN3A SCN3B SCN7A

2.70e-05235325GO:0034703
GeneOntologyCellularComponentmonoatomic ion channel complex

TRPC1 SCN1B SCN3A SCN3B SCN7A

2.54e-04378325GO:0034702
GeneOntologyCellularComponenttransmembrane transporter complex

TRPC1 SCN1B SCN3A SCN3B SCN7A

1.11e-03523325GO:1902495
GeneOntologyCellularComponentphotoreceptor cell cilium

KIAA1549 OPN4 ADGRV1

1.24e-03139323GO:0097733
GeneOntologyCellularComponenttransporter complex

TRPC1 SCN1B SCN3A SCN3B SCN7A

1.38e-03550325GO:1990351
GeneOntologyCellularComponent9+0 non-motile cilium

KIAA1549 OPN4 ADGRV1

1.63e-03153323GO:0097731
GeneOntologyCellularComponentphotoreceptor connecting cilium

KIAA1549 ADGRV1

2.45e-0348322GO:0032391
GeneOntologyCellularComponentnon-motile cilium

KIAA1549 OPN4 ADGRV1

3.30e-03196323GO:0097730
DomainXK_rel

XK XKR9 XKRY

7.47e-0711323IPR018629
DomainXK-related

XK XKR9 XKRY

7.47e-0711323PF09815
DomainNa_channel_b1/b3

SCN1B SCN3B

2.84e-062322IPR027098
DomainNa_channel_asu

SCN3A SCN7A

1.27e-0410322IPR001696
DomainNa_trans_assoc

SCN3A SCN7A

1.27e-0410322IPR010526
DomainNa_trans_assoc

SCN3A SCN7A

1.27e-0410322PF06512
DomainIon_trans_dom

TRPC1 SCN3A SCN7A

9.66e-04114323IPR005821
DomainIon_trans

TRPC1 SCN3A SCN7A

9.66e-04114323PF00520
DomainV-set

KDR SCN1B SCN3B

3.78e-03184323PF07686
DomainChannel_four-helix_dom

SCN3A SCN7A

4.28e-0357322IPR027359
Domain-

SCN3A SCN7A

4.28e-03573221.20.120.350
DomainIg_V-set

KDR SCN1B SCN3B

4.71e-03199323IPR013106
DomainIQ

SCN3A SCN7A

8.47e-0381322SM00015
DomainIG_LIKE

KDR IL1RL1 SCN1B SCN3B

9.47e-03491324PS50835
DomainIg-like_dom

KDR IL1RL1 SCN1B SCN3B

1.03e-02503324IPR007110
DomainIQ_motif_EF-hand-BS

SCN3A SCN7A

1.04e-0290322IPR000048
DomainEF-hand-dom_pair

SCN3A CAPN3 SCN7A

1.28e-02287323IPR011992
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN1B SCN3A SCN3B SCN7A

1.97e-0731244M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN1B SCN3A SCN3B SCN7A

2.25e-0732244M27455
PathwayREACTOME_CARDIAC_CONDUCTION

TRPC1 SCN1B SCN3A SCN3B SCN7A

2.28e-06130245M27454
PathwayWP_DRAVET_SYNDROME_SCN1AA1783V_POINT_MUTATION_MODEL

KDR SCN1B SCN3A SCN3B

6.50e-0673244MM16641
PathwayWP_DRAVET_SYNDROME

SCN1B SCN3A SCN3B

1.38e-0528243M45519
PathwayREACTOME_MUSCLE_CONTRACTION

TRPC1 SCN1B SCN3A SCN3B SCN7A

2.00e-05203245M5485
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

COL6A5 ADGRV1 TRPC1 SCN1B SCN3A SCN3B SCN7A

3.42e-05575247M29853
PathwayREACTOME_L1CAM_INTERACTIONS

SCN1B SCN3A SCN3B SCN7A

4.80e-05121244M872
PathwayREACTOME_SENSORY_PERCEPTION_OF_TASTE

TAS2R13 SCN1B SCN3A

6.69e-0547243M42524
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1B SCN3A SCN3B

1.55e-071232330175250
Pubmed

HNF4 alpha and the Ca-channel TRPC1 are novel disease candidate genes in diabetic nephropathy.

HNF4A TRPC1

8.20e-07232218184923
Pubmed

Study of the residues involved in the binding of β1 to β3 subunits in the sodium channel.

SCN1B SCN3B

8.20e-07232224581800
Pubmed

Structural basis for modulation of human NaV1.3 by clinical drug and selective antagonist.

SCN1B SCN3A

2.46e-06332235277491
Pubmed

Klotho is associated with VEGF receptor-2 and the transient receptor potential canonical-1 Ca2+ channel to maintain endothelial integrity.

KDR TRPC1

2.46e-06332220966350
Pubmed

Identification of functional voltage-gated Na(+) channels in cultured human pulmonary artery smooth muscle cells.

SCN1B SCN3A

2.46e-06332216052353
Pubmed

Transient Receptor Potential Canonical 1 (TRPC1) Channels as Regulators of Sphingolipid and VEGF Receptor Expression: IMPLICATIONS FOR THYROID CANCER CELL MIGRATION AND PROLIFERATION.

KDR TRPC1

2.46e-06332225971967
Pubmed

Sudden infant death syndrome-associated mutations in the sodium channel beta subunits.

SCN1B SCN3B

4.92e-06432220226894
Pubmed

Sodium channel beta1 and beta3 subunits associate with neurofascin through their extracellular immunoglobulin-like domain.

SCN1B SCN3B

4.92e-06432211470829
Pubmed

Contribution of Cardiac Sodium Channel β-Subunit Variants to Brugada Syndrome.

SCN1B SCN3B

4.92e-06432226179811
Pubmed

Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation.

SCN1B SCN3B

4.92e-06432221051419
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1B SCN3A

4.92e-06432235801810
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

SCN1B SCN3A SCN3B SCN7A

8.05e-0613932416985003
Pubmed

Mutations in sodium channel β1- and β2-subunits associated with atrial fibrillation.

SCN1B SCN3B

8.19e-06532219808477
Pubmed

Kell and Kx, two disulfide-linked proteins of the human erythrocyte membrane are phosphorylated in vivo.

XK XKRY

8.19e-0653229647734
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1B SCN3A

8.19e-06532224337656
Pubmed

Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks.

PER1 HNF4A

1.72e-05732230530698
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

MED12L PER1 XK HNF4A TRPC1

2.14e-0537132515747579
Pubmed

The identification of different endothelial cell populations within the mouse proepicardium.

KDR HNF4A

2.29e-05832221932312
Pubmed

The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome.

SCN1B SCN3B

2.29e-05832225757662
Pubmed

KDR identifies a conserved human and murine hepatic progenitor and instructs early liver development.

KDR HNF4A

2.94e-05932223746980
Pubmed

Endothelial cells are not required for specification of respiratory progenitors.

KDR HNF4A

2.94e-05932228501476
Pubmed

The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors.

PER1 HNF4A

2.94e-05932220159955
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1B SCN3A

2.94e-05932215746173
Pubmed

Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals.

SCN1B SCN3B

2.94e-05932217884088
Pubmed

Exposure of phosphatidylserine by Xk-related protein family members during apoptosis.

XK XKR9

3.67e-051032225231987
Pubmed

Melanopsin signalling in mammalian iris and retina.

OPN4 TRPC1

6.36e-051332222051675
Pubmed

Confirmation of quantitative trait loci for alcohol preference in mice.

SCN3A SCN7A

8.55e-05153229726281
Pubmed

Deficiency of autotaxin/lysophospholipase D results in head cavity formation in mouse embryos through the LPA receptor-Rho-ROCK pathway.

KDR HNF4A

8.55e-051532220692235
Pubmed

Small intestinal resident eosinophils maintain gut homeostasis following microbial colonization.

KDR IL1RL1

1.11e-041732235709757
Pubmed

Loss of PiT-1 results in abnormal endocytosis in the yolk sac visceral endoderm.

KDR HNF4A

1.11e-041732225138534
Pubmed

Genetic Targeting of Organ-Specific Blood Vessels.

KDR HNF4A

1.11e-041732229764841
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

MED12L KIAA1549 RNF213

1.11e-0410132310997877
Pubmed

Genetic lineage tracing identifies endocardial origin of liver vasculature.

KDR HNF4A

1.24e-041832227019112
Pubmed

Cyclic-Nucleotide- and HCN-Channel-Mediated Phototransduction in Intrinsically Photosensitive Retinal Ganglion Cells.

OPN4 TRPC1

1.70e-042132230270038
Pubmed

Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.

KDR HNF4A

1.87e-04223229136933
Pubmed

Brugada Syndrome

SCN1B SCN3B

2.24e-042432220301690
Pubmed

Visceral endoderm expression of Yin-Yang1 (YY1) is required for VEGFA maintenance and yolk sac development.

KDR HNF4A

2.43e-042532223554936
Pubmed

Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development.

KDR HNF4A

2.43e-042532236046192
Pubmed

Mab21l2 is essential for embryonic heart and liver development.

KDR HNF4A

2.43e-042532222412967
Pubmed

Deletion of Pdcd5 in mice led to the deficiency of placenta development and embryonic lethality.

KDR HNF4A

2.84e-042732228542142
Pubmed

Paternal obesity induces placental hypoxia and sex-specific impairments in placental vascularization and offspring metabolism†.

KDR HNF4A

2.84e-042732235377412
Pubmed

Inactivation of the Huntington's disease gene (Hdh) impairs anterior streak formation and early patterning of the mouse embryo.

KDR HNF4A

3.05e-042832216109169
Pubmed

ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification.

KDR HNF4A

3.51e-043032218462699
Pubmed

Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis.

COL6A5 KDR

5.65e-043832225572963
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

KIAA1549 RNF213 FAP GOLGA5 EIF4G3 JAGN1

7.02e-04120132635696571
CytobandEnsembl 112 genes in cytogenetic band chr2q24

FAP SCN3A SCN7A

9.67e-05127323chr2q24
GeneFamilyBlood group antigens|XK related family

XK XKR9 XKRY

2.21e-0711213955
GeneFamilyV-set domain containing|Immunoglobulin like domain containing|Sodium voltage-gated channel beta subunits

SCN1B SCN3B

7.70e-0642121204
GeneFamilyAdenosine receptors|V-set domain containing

KDR SCN1B SCN3B

8.49e-04163213590
GeneFamilyImmunoglobulin like domain containing

KDR IL1RL1 SCN1B

1.38e-03193213594
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

KDR IL1RL1

1.48e-02161212593
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

RNF213 KDR SCN3B SCN7A

7.48e-061823147af3b2029b7f55b923d5a4b764d4292f4ea48599
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_A|E18.5-samps / Age Group, Lineage, Cell class and subclass

RNF213 KDR SCN3B SCN7A

7.48e-06182314ea4f6c8f600ffe9f8e0609637b3371a5ac48ca03
ToppCellE18.5-samps-Endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

RNF213 KDR SCN3B SCN7A

7.48e-06182314e2d799e6e7526176a6fe6515b8fbe4d83d3a3ea1
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAP COL6A5 TNFAIP6 SCN7A

8.15e-061863145473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_granulocytic|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KIAA1549 IL1RL1 TNFAIP6 SCN7A

8.51e-0618831436ff615154d6d9e3ba6ccb73a0f11574bcbf5ece
ToppCellBronchial_Biopsy-Mesenchymal-Fibroblasts|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

FAP COL6A5 TNFAIP6 SCN7A

9.82e-061953145870b2956d50d6550a3174a220a6cc70c5538d70
ToppCellBronchial_Biopsy-Mesenchymal|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

FAP COL6A5 TNFAIP6 SCN7A

1.00e-05196314d37d821229dce716a05c2a5865415e10f79032de
ToppCelldistal-1-mesenchymal-Alveolar_Fibroblast|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FAP COL6A5 TNFAIP6 SCN7A

1.04e-051983146594c35ab203dc51462167c61807b0d49fa30fb2
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAP COL6A5 TNFAIP6 SCN7A

1.09e-052003148c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf|Entopeduncular / BrainAtlas - Mouse McCarroll V32

OPN4 TNFAIP6 ADGRV1

2.01e-0576313efbbbf91bca35720d8ecddb076f2c9f4de25e44d
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

OPN4 TNFAIP6 ADGRV1

2.01e-0576313254d18bece2676faa4bbeb8d48b1d327ab3c2215
ToppCelllymphoid-T_cell-pro-T_cell|lymphoid / Lineage, cell class and subclass

KIAA1549 IL1RL1 TNFAIP6

4.31e-05983134da11182885d5f2673e85bd9c5717939b0268427
ToppCellEndothelial-G|World / shred on cell class and cell subclass (v4)

KDR SCN1B SCN3A

8.68e-051243134b72809463f2986b7d1b7ab9de633ac4d7854a92
ToppCellCTRL-Lymphoid-pDC|CTRL / Disease state, Lineage and Cell class

MED12L FAP SCN3A

1.22e-04139313bbc10812b0c5b8c85e78171c12316becde8895c3
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_granulocytic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KIAA1549 IL1RL1 SCN7A

1.59e-0415231332634195048858ae84605c61e43c542d90f7cab5
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_granulocytic-mast_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KIAA1549 IL1RL1 SCN7A

1.59e-041523130eb185b2404f015efff1bd140e0c502d714720fb
ToppCellCOVID-19-Mast_cells|COVID-19 / group, cell type (main and fine annotations)

MED12L KIAA1549 IL1RL1

1.71e-04156313159504d43421ee83b9ab484816333ae549c9c2fd
ToppCellCOVID-19-Mast_cells-Mast_cells|COVID-19 / group, cell type (main and fine annotations)

MED12L KIAA1549 IL1RL1

1.71e-04156313bc10b94673184ef384c6665b16a1209a8975a4f1
ToppCell3'_v3-blood-Lymphocytic_Invariant-Inducer-like-ILC3|blood / Manually curated celltypes from each tissue

MED12L ERMARD SCN1B

1.74e-04157313eb2520c237543ea4869d4386afc0457b111f6193
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAP COL6A5 SCN7A

1.74e-04157313f147e24f2ece82e1c54750868954d09b3c461804
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAP COL6A5 SCN7A

1.78e-04158313e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_granulocytic-mast_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KIAA1549 IL1RL1 SCN7A

1.81e-04159313ecd1daa33549541aee3bf4e139ab6732efc8e74c
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_granulocytic|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KIAA1549 IL1RL1 SCN7A

1.81e-041593137b6370c9567da7d40541c6e243efa704ed7e90ae
ToppCell356C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

COL6A5 XK SCN7A

1.84e-041603130293b244c063a62819690bf22bbc2681f8d15252
ToppCell356C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

COL6A5 XK SCN7A

1.84e-041603133eaae86fa08f7651021316f8e5811bf48055591e
ToppCellPND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDR SCN1B SCN3A

1.88e-04161313133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDR SCN1B SCN3A

1.88e-04161313cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDR SCN1B SCN3A

1.88e-041613139466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDR SCN1B SCN3A

1.91e-0416231396c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

RNF213 KDR SCN7A

1.95e-04163313d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDR SCN1B SCN3A

2.02e-04165313347b59aa625a8a960828b8620824d8ac48990e07
ToppCellEndothelial-B-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

KDR SCN3A SCN3B

2.02e-04165313b6893882472aeb0d18e26f47eaec9d53688afcde
ToppCellPND03-Endothelial-Endothelial_lymphatic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDR SCN1B SCN3A

2.02e-041653131890f9c33b0c5b381d57f97042da2610a093a6de
ToppCellnucseq-Immune-Hematopoietic-Granulocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MED12L KIAA1549 IL1RL1

2.02e-0416531337615622c736e43260c38016e7c9e565ac97a3e8
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDR SCN1B SCN3A

2.02e-04165313507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDR SCN1B SCN3A

2.02e-0416531339a25be081a5d59c7cf107a997d352793d5025fb
ToppCellnucseq-Immune-Hematopoietic-Granulocytic-Mast/Basophil|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MED12L KIAA1549 IL1RL1

2.02e-04165313640bb71e74a61df2fcb01ceeabe4c493ef836b21
ToppCellnucseq-Immune-Hematopoietic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MED12L KIAA1549 IL1RL1

2.02e-04165313f3df74b5763130c71c0a482a3a23f6b22acc2892
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|356C / Donor, Lineage, Cell class and subclass (all cells)

KDR SCN3A SCN3B

2.05e-041663136bd5aa205b6e4b88ba9f8cd0999e2191d7d1d16c
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|356C / Donor, Lineage, Cell class and subclass (all cells)

KDR SCN3A SCN3B

2.05e-041663135ba45407a47207ff01e4a3f9f5d91d8247fe9b6f
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAP CAPN3 SCN7A

2.05e-04166313aa2df07eff323ded751ced8938af08223d7f2029
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAP CAPN3 SCN7A

2.05e-04166313695298a94d62b8adab083900003ec636fbaae5d9
ToppCellEndothelial-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

KDR SCN3A SCN3B

2.05e-04166313c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

PER1 ADGRV1 PHTF1

2.09e-04167313c0c944eae0514dc8e00d0c2892a0792e157695ec
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDR SCN3B SCN7A

2.13e-0416831355c9de7b3a1d6cf7b02b020ff92ab4ede8d195cc
ToppCellEndothelial-B-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

KDR SCN3A SCN3B

2.13e-041683134977c3837fbb1f36c89fddd5764e37290ac25ad8
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDR SCN1B SCN3A

2.17e-04169313f077e39e41fffe7672541f5b72b80faaf56c597c
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDR SCN3B SCN7A

2.17e-0416931341ad349806b279fbe1374b7e3cc7f146a11adb44
ToppCellEndothelial-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

KDR SCN3A SCN3B

2.17e-0416931395c617143e1fbdd1d55a93ffdcc210e0be37cf2f
ToppCellfacs-Heart-LV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAP TNFAIP6 SCN1B

2.17e-04169313849a8f8509c58d65462a09c84d58b6ecdc8934f5
ToppCellControl-Mast_cells|Control / group, cell type (main and fine annotations)

MED12L KIAA1549 IL1RL1

2.17e-04169313fdb9abca1d0f4fdc32dd8ac6231651ef34aa5afb
ToppCellEndothelial-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

KDR SCN3A SCN3B

2.17e-041693138889c9e8af1ab0b093d57b69abd80b59b3461be9
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDR SCN3B SCN7A

2.17e-0416931342782c61592742190ab0cba8a94f8bdf9c278f90
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDR SCN1B SCN3A

2.20e-0417031335e3945d8a540a3e2cec1b559316265aaad023d1
ToppCell390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

IL1RL1 TRPC1 CAPN3

2.20e-04170313a6fa0cab1fa829ec601fe48306b4c43c83425b04
ToppCell390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

IL1RL1 TRPC1 CAPN3

2.20e-04170313b40255eee45eb18b5a297336d7f3845fd8f8aa3b
ToppCellControl-Mast_cells-Mast_cells|Control / group, cell type (main and fine annotations)

MED12L KIAA1549 IL1RL1

2.20e-04170313c80f6d29096c372da95a8407f402349ff1bb7018
ToppCellPND01-Endothelial-Endothelial_lymphatic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDR SCN1B SCN3A

2.20e-041703130ea625abaa25bab93b70b7000e8f90d5c0f9a0fb
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDR SCN1B SCN3A

2.20e-041703130b5ddc7d452db0a389927a367914f7d257703f7e
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_Erythro-Mega|lymph-node_spleen / Manually curated celltypes from each tissue

MED12L COL6A5 XK

2.24e-041713133ecd0a074344179c57eb2d9a857ba594904d00fa
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KDR SCN3B SCN7A

2.28e-04172313490745024730df6357f6c2b81d7a64e21557c0d5
ToppCell3'_v3-blood-Mast|blood / Manually curated celltypes from each tissue

MED12L KIAA1549 IL1RL1

2.28e-04172313e7a46bbeff749ca59b9f1357409ce1ad59dd22dd
ToppCellEndothelial-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

KDR TRPC1 SCN3A

2.28e-04172313d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCellEndothelial-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

KDR SCN3A SCN3B

2.28e-041723138a527dff06d841a86c7eb04a1dd9630787294da4
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KDR SCN3A SCN3B

2.32e-041733137dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

PER1 ADGRV1 PHTF1

2.32e-0417331342c911ed16fabdabef063830e8407192d8bde950
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D122|Adult / Lineage, Cell type, age group and donor

KDR SCN3A SCN3B

2.32e-04173313dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCellBAL-Severe-Myeloid-Neutrophil-Neutrophil-Neu_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RNF213 FAP TNFAIP6

2.32e-041733131edef5aeab626cbf2c09468e77b02cfa2d21ba03
ToppCellBAL-Severe-Myeloid-Neutrophil-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RNF213 FAP TNFAIP6

2.32e-04173313c37dba3804df7c3151e18e6ae4e0b6e7a92bae97
ToppCellEndothelial-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

KDR SCN3A SCN3B

2.32e-04173313a81992965137195d20fc498f750975303961a828
ToppCellBAL-Severe-Myeloid-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RNF213 FAP TNFAIP6

2.32e-041733135b76d9cc56bbb29017e64a2d0a3c76c0be003d96
ToppCellBAL-Severe-Myeloid-Neutrophil-Neutrophil-Neu_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNF213 FAP TNFAIP6

2.32e-04173313bf685025961e79b379f2c35464b6c8ce3e31ace0
ToppCellBAL-Severe-Myeloid-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNF213 FAP TNFAIP6

2.32e-04173313a6e73a40b0d5356564a594053e772f9d061a5919
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Mast_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIAA1549 IL1RL1 SCN7A

2.32e-04173313a7dee23b1d43d3070d502487af319ff81a9a747b
ToppCellBAL-Severe-Myeloid-Neutrophil-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNF213 FAP TNFAIP6

2.32e-04173313a8b5370f4c893a20c58e97659f3ac168699693f8
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND01-03-samps / Age Group, Lineage, Cell class and subclass

KDR SCN3B SCN7A

2.36e-04174313b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high|PND01-03-samps / Age Group, Lineage, Cell class and subclass

KDR SCN3B SCN7A

2.36e-04174313cb0109661e8c9ca04d67d33f2d926f0e649bf67d
ToppCell343B-Fibroblasts-Fibroblast-H-|343B / Donor, Lineage, Cell class and subclass (all cells)

FAP TNFAIP6 TMEM121

2.36e-041743132627c3983009839fedbc5e3f628739dc026447f4
ToppCell10x5'-GI_small-bowel-Mast|GI_small-bowel / Manually curated celltypes from each tissue

KIAA1549 IL1RL1 SCN7A

2.36e-04174313e94c980b25edfd0e8598c416828801fcc00e8ead
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MED12L ADGRV1 TMEM121

2.36e-0417431346bd0ef7d0541386de7a901d85d53d0176dc92bf
ToppCell10x5'-GI_small-bowel-Mast-Mast_cells|GI_small-bowel / Manually curated celltypes from each tissue

KIAA1549 IL1RL1 SCN7A

2.36e-0417431305525bf0a2bde2be4f7c147b17a24530ce8819e0
ToppCell343B-Fibroblasts-Fibroblast-H|343B / Donor, Lineage, Cell class and subclass (all cells)

FAP TNFAIP6 TMEM121

2.36e-04174313507a33e58f62e2b72f0bcc743e84dbd0bf705a15
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN1B SCN3A SCN3B

2.40e-04175313f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCellNS-moderate-d_07-13-Lymphoid-NK|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KDR TRPC1 CAPN3

2.40e-04175313f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAP TNFAIP6 SCN1B

2.44e-04176313f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-4|TCGA-Lung / Sample_Type by Project: Shred V9

RNF213 FAP KDR

2.44e-041763130923b01137d6f9956ca815b41102c81e82624065
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3-5_THEMIS_ELOF1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAP XKR9 SCN1B

2.44e-0417631378306517b1e52411a2ba72f141efea4d12c09f25
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAP TNFAIP6 SCN1B

2.44e-04176313fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL6A5 OPN4 SCN7A

2.48e-041773132b675840b7d2bb536c2c600936733bd9e97e7120
ToppCellSevere_COVID-19-Myeloid-Neutrophil|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

RNF213 FAP TNFAIP6

2.48e-04177313a6fae376f1beb1df423484d9b1bd1d954ca117af
ToppCell368C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

XK ABCD1 SCN1B

2.48e-04177313946803293a7955116c80f403e99e4093e798ca3f
ToppCellCOVID-19-Heart-Lymph_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

KDR SCN3A SCN3B

2.48e-04177313326fde0734ef0d7272693966d346ca479b9d8147
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KDR SCN3A SCN3B

2.52e-04178313ad3de3e03a401dac64431a541899445262246347
ToppCellE17.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KDR SCN3B SCN7A

2.52e-04178313982205ba117a4c7b7e9b713689a5b69190f0bca9
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAP XKR9 SCN1B

2.52e-04178313674ee5095b98929c29e4f6bd56029a336cc4a38c
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KDR SCN3A SCN3B

2.56e-0417931335fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KDR SCN3A SCN3B

2.56e-04179313ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

IL1RL1 TNFAIP6 XKR9

2.56e-0417931387f608b137aae34572b150492a83a3a127cff40b
ToppCell3'_v3-bone_marrow-Mast|bone_marrow / Manually curated celltypes from each tissue

MED12L KIAA1549 IL1RL1

2.61e-04180313b37ee81b792213d6595b4ec65d04bc35d83321c7
ToppCell3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAP KDR OPN4

2.61e-04180313efc4c5a4dea456527526bbfd88cf70d803893671
Drugdiprafenone

SCN1B SCN3A SCN3B SCN7A

1.23e-0819324CID000071249
DrugAC1NT1AF

SCN1B SCN3A SCN3B SCN7A

3.98e-0825324CID005322157
DrugPirmenolum

SCN1B SCN3A SCN3B SCN7A

4.70e-0826324CID000004853
Drugfenpropathrin

SCN1B SCN3A SCN3B

5.03e-086323ctd:C044267
DrugAC1L1MOZ

SCN1B SCN3A SCN3B SCN7A

5.51e-0827324CID000031958
Drugnefopam

SCN1B SCN3A SCN3B SCN7A

5.51e-0827324CID000004450
DrugPbTx-1

SCN1B SCN3A SCN3B SCN7A

5.51e-0827324CID006437089
Drugparaben

SCN1B SCN3A SCN3B SCN7A

6.42e-0828324CID000007175
Drugtocainide

SCN1B SCN3A SCN3B SCN7A

8.58e-0830324CID000038945
DrugNSC93767

SCN1B SCN3A SCN3B SCN7A

1.12e-0732324CID000005658
Drug5-hydroxypropafenone

SCN1B SCN3A SCN3B SCN7A

1.45e-0734324CID000107927
Drugbenzocaine

SCN1B SCN3A SCN3B SCN7A

2.05e-0737324CID000002337
Drugaprindine

SCN1B SCN3A SCN3B SCN7A

2.29e-0738324CID000002218
Drugtrimethoprim

PER1 SCN1B SCN3A SCN3B SCN7A

2.58e-0799325CID000005578
DrugS-ropivacaine

SCN1B SCN3A SCN3B SCN7A

2.83e-0740324CID000071273
Drugpilsicainide

SCN1B SCN3A SCN3B SCN7A

5.03e-0746324CID000004820
Drugspiradoline

SCN1B SCN3A SCN3B SCN7A

5.03e-0746324CID000005620
Drugindoxacarb

SCN1B SCN3A SCN3B SCN7A

6.51e-0749324CID000107720
DrugAC1NSN3X

SCN1B SCN3A SCN3B SCN7A

9.67e-0754324CID005366189
DrugAC1L1W4O

KDR SCN1B SCN3B

1.13e-0615323CID000036625
Drugtriamterene

SCN1B SCN3A SCN3B SCN7A

1.29e-0658324CID000005546
Drugzonisamide

SCN1B SCN3A SCN3B SCN7A

1.69e-0662324CID000005734
Drugsaxitoxin

SCN1B SCN3A SCN3B SCN7A

2.05e-0665324CID000037165
DrugAC1L1CQC

SCN1B SCN3A SCN3B SCN7A

2.05e-0665324CID000002012
Drugmexiletine

SCN1B SCN3A SCN3B SCN7A

2.18e-0666324CID000004178
Drugresiniferatoxin

SCN1B SCN3A SCN3B SCN7A

2.18e-0666324CID000104826
Drugdisopyramide

SCN1B SCN3A SCN3B SCN7A

2.18e-0666324CID000003114
Drugdibucaine

SCN1B SCN3A SCN3B SCN7A

2.46e-0668324CID000003025
DrugGBR 12909

SCN1B SCN3A SCN3B SCN7A

2.61e-0669324CID000003455
DrugT2755

SCN1B SCN3A SCN3B SCN7A

2.92e-0671324CID000005514
Drugflecainide

SCN1B SCN3A SCN3B SCN7A

2.92e-0671324CID000003355
Drugimide

SCN1B SCN3A SCN3B SCN7A

3.45e-0674324CID000443040
Drug1, 3-diallylurea

SCN1B SCN3A SCN3B SCN7A

3.45e-0674324CID000074537
Drugdiphenhydramine

SCN1B SCN3A SCN3B SCN7A

3.64e-0675324CID000003100
Drugfenfluramine

HNF4A SCN1B SCN3A SCN3B SCN7A

4.68e-06178325CID000003337
Drugbupropion

SCN1B SCN3A SCN3B SCN7A

4.95e-0681324CID000000444
Drugstrychnine HCl

ADGRV1 SCN1B SCN3A SCN3B SCN7A

5.08e-06181325CID000005304
DrugAcenocoumarol [152-72-7]; Down 200; 11.4uM; HL60; HG-U133A

PER1 RBM25 ABCD1 EIF4G3 PHTF1

7.68e-061973251394_DN
Drugcyfluthrin

SCN1B SCN3A SCN3B

8.99e-0629323ctd:C052570
Drugpropafenone

SCN1B SCN3A SCN3B SCN7A

1.06e-0598324CID000004932
Drugpyrethrin

KDR SCN1B SCN3B

1.10e-0531323CID000011442
Drugisradipine

SCN1B SCN3A SCN3B SCN7A

1.15e-05100324CID000003784
DrugAC1NPPZW

XK TRPC1 SCN1B SCN3B

1.29e-05103324CID005183170
Drugpentobarbital

XK SCN1B SCN3A SCN3B SCN7A

1.43e-05224325CID000004737
Druglamotrigine

SCN1B SCN3A SCN3B SCN7A

2.06e-05116324CID000003878
Drughydrochlorothiazide

SCN1B SCN3A SCN3B SCN7A

2.35e-05120324CID000003639
Drugbupivacaine

SCN1B SCN3A SCN3B SCN7A

2.76e-05125324CID000002474
Drugbepridil

SCN1B SCN3A SCN3B SCN7A

2.85e-05126324CID000002351
Drugketamine

XK SCN1B SCN3A SCN3B SCN7A

3.03e-05262325CID000003821
Drugmanganese chloride

PER1 IL1RL1 TNFAIP6 SCN3B PHTF1 SCN7A

3.64e-05456326ctd:C025340
Drugtriphosphoinositide

TRPC1 SCN1B SCN3A SCN3B SCN7A

3.69e-05273325CID009543520
Drugisoflurane

XK SCN1B SCN3A SCN3B SCN7A

4.09e-05279325CID000003763
Drugclenbuterol

SCN1B SCN3A SCN3B SCN7A

4.55e-05142324CID000002783
Drugsalbutamol

SCN1B SCN3A SCN3B SCN7A

5.07e-05146324CID000002083
Druglacosamide

ADGRV1 SCN1B SCN3B

5.32e-0552323CID000219078
Drug2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate

SCN1B SCN3A

5.33e-058322ctd:C489827
Drugprocaine

SCN1B SCN3A SCN3B SCN7A

6.09e-05153324CID000004914
Drugdihydrochloride

SCN1B SCN3A SCN3B SCN7A

7.07e-05159324CID000070978
Druglidocaine

SCN1B SCN3A SCN3B SCN7A

7.24e-05160324CID000003676
Drugamiodarone

SCN1B SCN3A SCN3B SCN7A

7.24e-05160324CID000002156
Druggabapentin

SCN1B SCN3A SCN3B SCN7A

8.96e-05169324CID000003446
Drugriluzole

SCN1B SCN3A SCN3B SCN7A

1.00e-04174324CID000005070
Drugtoluene

SCN1B SCN3A SCN3B SCN7A

1.02e-04175324CID000001140
DrugRH-3421

SCN1B SCN3B

1.04e-0411322CID000108039
Drugchloroacetylajmaline

SCN1B SCN3B

1.04e-0411322CID000038681
Drugcarbamazepine

SCN1B SCN3A SCN3B SCN7A

1.12e-04179324CID000002554
DrugNSC7524

SCN1B SCN3A SCN3B SCN7A

1.19e-04182324CID000005657
Drugpseudococaine

PER1 TNFAIP6 SCN1B SCN3A SCN3B SCN7A

1.25e-04570326CID000002826
DrugRo 22-9194

SCN1B SCN3B

1.25e-0412322CID000129209
Drugsynthetic pyrethrins

KDR SCN1B SCN3B

1.35e-0471323CID000002982
DrugPyrethroids

KDR SCN1B SCN3B

1.35e-0471323CID000005053
Drugprocainamide

SCN1B SCN3A SCN3B SCN7A

1.41e-04190324CID000004913
Drugpropofol

SCN1B SCN3A SCN3B SCN7A

1.44e-04191324CID000004943
DrugCID6432355

SCN1B SCN3B

1.48e-0413322CID006432355
DrugAC1LCJM3

SCN1B SCN3B

1.48e-0413322CID000631640
DrugCyclopenthiazide [742-20-1]; Down 200; 10.6uM; MCF7; HT_HG-U133A

PER1 ABCD1 TRPC1 TMEM121

1.65e-041983247325_DN
Drugvinblastine sulfate; Down 200; 0.1uM; MCF7; HT_HG-U133A

FAP XK HNF4A TMEM121

1.65e-041983247517_DN
DrugSotalol hydrochloride [959-24-0]; Up 200; 13uM; PC3; HT_HG-U133A

KDR IL1RL1 TNFAIP6 SCN3A

1.65e-041983244079_UP
Druggadolinium

KDR ABCD1 ADGRV1 TRPC1

1.68e-04199324CID000023982
Drugwortmannin from Penicillium funiculosum; Down 200; 0.01uM; MCF7; HT_HG-U133A

PER1 XK ABCD1 TRPC1

1.71e-042003245603_DN
Drugbioallethrin

KDR SCN1B

1.72e-0414322ctd:C018465
Druglorcainide

SCN1B SCN3B

1.72e-0414322CID000042883
Drugoctylguanidine

SCN1B SCN3B

1.72e-0414322CID000030621
Drugvalproate

ADGRV1 GOLGA5 SCN1B SCN3B PHTF1

1.77e-04381325CID000003121
Drugtrimethyloxonium

SCN1B SCN3B

1.99e-0415322CID000093245
DrugQX-314

TRPC1 SCN1B SCN3B

2.07e-0482323CID000003925
DrugSodium

SCN1B SCN3A SCN3B

2.22e-0484323ctd:D012964
Drugtrans-permethrin

KDR SCN1B SCN3B

2.38e-0486323CID000040159
Drugquindine

SCN1B SCN3A SCN3B SCN7A

2.42e-04219324CID000001065
Drugphenytoin

SCN1B SCN3A SCN3B SCN7A

2.42e-04219324CID000001775
DrugAsbestos, Crocidolite

PER1 TMEM156 RNF213 KDR RBM25 IL1RL1 TAS2R13 TNFAIP6

2.48e-041241328ctd:D017638
Drugarticaine

SCN1B SCN3B

2.57e-0417322CID000032169
Druglifarizine

SCN1B SCN3B

2.57e-0417322CID000071336
Drugsodium

XK TRPC1 SCN1B SCN3A SCN3B PHTF1 SCN7A

2.79e-04944327CID000000923
Drugmoricizine

SCN1B SCN3B

2.89e-0418322CID000034632
Drugfenvalerate

SCN1B SCN3A SCN3B

3.40e-0497323ctd:C017690
DrugBDF 9148

SCN1B SCN3B

3.95e-0421322CID000123765
Druglactate

ADGRV1 SCN1B SCN3A SCN3B SCN7A

4.27e-04461325CID000000612
Drugpyraclofos

SCN1B SCN3B SCN7A

4.41e-04106323CID000093460
DrugAC1L1CD9

XK TMEM121

4.75e-0423322CID000001844
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1B SCN3A SCN7A

2.53e-0712323DOID:0060170 (implicated_via_orthology)
DiseaseBrugada syndrome

SCN1B SCN3B

3.18e-058322cv:C1142166
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

ADGRV1 SCN1B

4.08e-059322C3502809
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN3A SCN7A

5.10e-0510322DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN3A SCN7A

5.10e-0510322DOID:0080422 (implicated_via_orthology)
DiseaseOther specified cardiac arrhythmias

SCN1B SCN3B

6.23e-0511322C0348626
DiseaseNodal rhythm disorder

SCN1B SCN3B

6.23e-0511322C0264893
DiseaseEctopic rhythm

SCN1B SCN3B

6.23e-0511322C1399226
DiseaseCARDIAC CONDUCTION DEFECT, NONSPECIFIC (disorder)

SCN1B SCN3B

6.23e-0511322C2748542
DiseaseBrugada Syndrome 1

SCN1B SCN3B

8.82e-0513322C4551804
DiseaseSinus Node Dysfunction (disorder)

SCN1B SCN3B

1.19e-0415322C0428908
DiseaseAcute Lung Injury

IL1RL1 TNFAIP6

2.60e-0422322C0242488
DiseaseATRIAL FIBRILLATION, FAMILIAL, 1 (disorder)

SCN1B SCN3B

2.60e-0422322C1843687
DiseaseBrugada Syndrome (disorder)

SCN1B SCN3B

3.10e-0424322C1142166
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

HNF4A TRPC1 SCN1B

5.40e-04147323DOID:9352 (biomarker_via_orthology)
Diseasefibrinogen measurement, tissue plasminogen activator measurement

HNF4A CAPN3

1.10e-0345322EFO_0004623, EFO_0004791
Diseasefibrinogen measurement, plasminogen activator inhibitor 1 measurement

HNF4A CAPN3

1.10e-0345322EFO_0004623, EFO_0004792
Diseaseobesity (implicated_via_orthology)

MED12L HNF4A CAPN3

1.62e-03215323DOID:9970 (implicated_via_orthology)
DiseaseIschemic stroke, fibrinogen measurement

HNF4A CAPN3

1.63e-0355322EFO_0004623, HP_0002140

Protein segments in the cluster

PeptideGeneStartEntry
MKYLEESVWLHLLII

ADGRV1

1416

Q8WXG9
VFIVKMWRLLIYETE

RBM25

821

P49756
VVMVIVVILYWKLCR

KIAA1549

1311

Q9HCM3
QINLILLERLWYVML

ABCD1

316

P33897
YLTWILDVLEKIRPM

MED12L

251

Q86YW9
EIKKLIYVHLVIWLL

JAGN1

36

Q8N5M9
IYVHLVIWLLLVAKM

JAGN1

41

Q8N5M9
VIIYMALLHLWVMIV

GOLGA5

701

Q8TBA6
MKEQLLVLVEWAKYI

HNF4A

191

P41235
VIKYVLQDPIWLLMA

PER1

1121

O15534
KIMLLVILLFVLSWA

OPN4

296

Q9UHM6
LVIILKMFWIEATLL

IL1RL1

346

Q01638
MKILLIIFVLIIWTE

COL6A5

1

A8TX70
FILKIMLPYWEVALV

ERMARD

266

Q5T6L9
IIKLNVLEWLQLTMY

CAPN3

806

P20807
IWLYLAELVTPMLKE

EIF4G3

1316

O43432
YLKWRVNKVILMILL

TAS2R13

121

Q9NYV9
LLYVIIMAEKVLWVL

OR8K1

136

Q8NGG5
IMAEKVLWVLVIVPY

OR8K1

141

Q8NGG5
VFTYIFILEMLLKWV

SCN3A

1246

Q9NY46
SMKITWYILVLLVFI

TMEM156

211

Q8N614
LEVDEITLWYKMILP

FAP

511

Q12884
ERIDYLLILWIIGMI

TRPC1

421

P48995
IWVFLFKLLILQYLM

RNF213

2066

Q63HN8
MIILIYLFLLLWEDT

TNFAIP6

1

P98066
AIKLQVIKLIYLMIW

XKRY

36

O14609
VIKLIYLMIWHSLVI

XKRY

41

O14609
VWLLLLYFMQVIAIV

PHTF1

101

Q9UMS5
MILWFLYIFVLEIKL

TMEM121

76

Q9BTD3
IMMYVLIVVLTIWLV

SCN1B

161

Q07699
LIVVLTIWLVAEMIY

SCN1B

166

Q07699
MMYILLVFLTLWLLI

SCN3B

161

Q9NY72
AIKLQVIKLIYLMIW

XKRY2

36

A2RUG3
VIKLIYLMIWHSLVI

XKRY2

41

A2RUG3
LISWLIIVNMYIVVV

SCN7A

1481

Q01118
MFFWLLLVIILRTVK

KDR

776

P35968
YMIRFIENAILLLLW

XK

321

P51811
WMLSVVLLLFLNVKI

XKR9

216

Q5GH70