Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SOX1 SOX4 ONECUT2 TBX3 DACH1 POU2F1 IRX3 HOXA11 SP8 SAFB SKOR2 SP9 SUZ12 PAX7 OLIG2 TBX1 ZNF367 FOXC1 FOXD1	8.61e-05	1244	115	19	GO:0000978
GeneOntologyMolecularFunction	mono-olein transacylation activity	PNPLA2 PNPLA4	9.83e-05	3	115	2	GO:0051264
GeneOntologyMolecularFunction	diolein transacylation activity	PNPLA2 PNPLA4	9.83e-05	3	115	2	GO:0051265
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	SOX1 SOX4 ONECUT2 TBX3 DACH1 POU2F1 IRX3 HOXA11 SP8 SAFB SKOR2 SP9 SUZ12 PAX7 OLIG2 TBX1 ZNF367 FOXC1 FOXD1	1.14e-04	1271	115	19	GO:0000987
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	SOX1 SOX4 ONECUT2 TBX3 DACH1 POU2F1 YBX3 IRX3 HOXA11 SP8 SAFB SKOR2 SP9 SUZ12 PAX7 OLIG2 TBX1 ZNF367 FOXC1 FOXD1	2.37e-04	1459	115	20	GO:0000977
GeneOntologyMolecularFunction	chromatin binding	POLG MKRN1 POU2F1 JARID2 TRIM33 ARID1B SAFB TLE1 TLE4 SKOR2 CHD6 SUZ12 FOXC1	3.33e-04	739	115	13	GO:0003682
GeneOntologyMolecularFunction	histone methyltransferase activity	SETD1B JARID2 SETBP1 SUZ12	7.54e-04	71	115	4	GO:0042054
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	SOX1 SOX4 IRF2BP2 ZNF703 TBX3 DACH1 IRAK1 JPH2 POU2F1 YBX3 IRX3 PPP1R13L JARID2 TRIM33 TLE1 TLE4 SKOR2 SUZ12 HDAC10 OLIG2 TBX1 FOXC1 FOXD1	2.78e-06	1399	116	23	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	SOX1 SOX4 IRF2BP2 ZNF703 TBX3 DACH1 IRAK1 JPH2 POU2F1 YBX3 IRX3 PPP1R13L JARID2 TRIM33 TLE1 TLE4 SKOR2 SUZ12 HDAC10 OLIG2 TBX1 FOXC1 FOXD1	3.29e-06	1413	116	23	GO:1902679
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	SOX1 SOX4 IRF2BP2 TBX3 DACH1 JPH2 YBX3 IRX3 PPP1R13L JARID2 TRIM33 TLE1 TLE4 SKOR2 SUZ12 HDAC10 OLIG2 TBX1 FOXC1	6.31e-06	1053	116	19	GO:0000122
GeneOntologyBiologicalProcess	pattern specification process	SOX1 TDRD5 TBX3 SHROOM3 IRX3 NCLN HOXA11 SP8 DCHS1 PAX7 TBX1 FOXC1 FOXD1	8.35e-06	526	116	13	GO:0007389
GeneOntologyBiologicalProcess	embryo development	EPHB2 TDRD5 TBX3 FRAS1 SHROOM3 HCN4 INTS1 POU2F1 YBX3 IRX3 PPP1R13L HOXA11 SP8 SLC39A12 PRICKLE2 DCHS1 SP9 PAX7 NOCT MMP14 TBX1 FOXC1	1.47e-05	1437	116	22	GO:0009790
GeneOntologyBiologicalProcess	kidney morphogenesis	SOX4 FRAS1 IRX3 HOXA11 DCHS1 FOXD1	3.89e-05	111	116	6	GO:0060993
GeneOntologyBiologicalProcess	chromatin organization	SOX1 TDRD5 SETD1B CHD9 HUWE1 EZHIP JARID2 ARID1B SAFB UBR5 SETBP1 CENPV CHD6 SUZ12 PAX7 HDAC10	4.17e-05	896	116	16	GO:0006325
GeneOntologyBiologicalProcess	chromatin remodeling	TDRD5 SETD1B CHD9 HUWE1 EZHIP JARID2 ARID1B UBR5 SETBP1 CENPV CHD6 SUZ12 PAX7 HDAC10	7.21e-05	741	116	14	GO:0006338
GeneOntologyBiologicalProcess	regionalization	SOX1 TDRD5 TBX3 IRX3 NCLN HOXA11 SP8 PAX7 TBX1 FOXC1 FOXD1	8.14e-05	478	116	11	GO:0003002
GeneOntologyBiologicalProcess	atrioventricular bundle cell differentiation	TBX3 IRX3	9.37e-05	3	116	2	GO:0003167
GeneOntologyBiologicalProcess	cytoplasm protein quality control by the ubiquitin-proteasome system	UBR4 UBR5	9.37e-05	3	116	2	GO:0071629
GeneOntologyBiologicalProcess	cytoplasm protein quality control	UBR4 UBR5	9.37e-05	3	116	2	GO:0140455
GeneOntologyBiologicalProcess	protein-DNA complex organization	SOX1 TDRD5 SETD1B CHD9 HUWE1 EZHIP JARID2 ARID1B SAFB UBR5 SETBP1 CENPV CHD6 SUZ12 PAX7 HDAC10	1.49e-04	999	116	16	GO:0071824
GeneOntologyBiologicalProcess	His-Purkinje system cell differentiation	TBX3 IRX3	1.87e-04	4	116	2	GO:0060932
GeneOntologyBiologicalProcess	embryonic morphogenesis	EPHB2 TBX3 FRAS1 SHROOM3 POU2F1 IRX3 HOXA11 SP8 SLC39A12 SP9 MMP14 TBX1 FOXC1	1.88e-04	713	116	13	GO:0048598
GeneOntologyBiologicalProcess	regulation of postsynaptic density assembly	ABI3 SIPA1L1 PRICKLE2	2.14e-04	21	116	3	GO:0099151
GeneOntologyBiologicalProcess	mesoderm development	TBX3 IRX3 NCLN HOXA11 TBX1 FOXC1	2.63e-04	157	116	6	GO:0007498
GeneOntologyCellularComponent	chromatin	SOX1 SOX4 ONECUT2 TBX3 POU2F1 IRX3 JARID2 TRIM33 SP8 ARID1B UBR5 SP9 CHD6 SUZ12 PAX7 ALDOA OLIG2 TBX1 FOXC1 FOXD1	1.56e-04	1480	115	20	GO:0000785
MousePheno	lethality during fetal growth through weaning, complete penetrance	SOX4 IRF2BP2 TBX3 FRAS1 SHROOM3 SPINK1 UBR4 DACH1 POU2F1 SOCS7 JARID2 SP8 ARID1B SAFB LLGL1 CDK13 SLC19A1 SKOR2 DCHS1 SP9 CAMTA1 MMP14 OLIG2 AGRN TBX1 FOXC1 NOVA1 FOXD1	1.50e-08	1269	96	28	MP:0011111
MousePheno	abnormal kidney development	FRAS1 CDK13 SLC19A1 DCHS1 MMP14 FOXC1 FOXD1	3.38e-06	93	96	7	MP:0000527
MousePheno	abnormal urinary system development	FRAS1 CDK13 SLC19A1 DCHS1 MMP14 FOXC1 FOXD1	1.10e-05	111	96	7	MP:0003942
MousePheno	abnormal oviduct size	CBL SAFB FOXC1	2.56e-05	9	96	3	MP:0009063
MousePheno	abnormal ureteric bud morphology	FRAS1 DCHS1 MMP14 FOXC1 FOXD1	4.34e-05	57	96	5	MP:0006032
MousePheno	perinatal lethality, complete penetrance	SHROOM3 UBR4 DACH1 JARID2 SP8 ARID1B SAFB LLGL1 SKOR2 DCHS1 OLIG2 AGRN TBX1 FOXC1 FOXD1	9.67e-05	712	96	15	MP:0011089
MousePheno	abnormal striatum morphology	SOX1 LLGL1 TRIM67 SP9 FOXC1	1.62e-04	75	96	5	MP:0004077
MousePheno	abnormal oviduct morphology	CBL SAFB FOXC1	1.65e-04	16	96	3	MP:0003574
MousePheno	impaired branching involved in ureteric bud morphogenesis	FRAS1 DCHS1 MMP14 FOXD1	1.74e-04	41	96	4	MP:0004936
MousePheno	cleft secondary palate	TBX3 FRAS1 SP8 CDK13 SKOR2 TBX1	2.37e-04	127	96	6	MP:0009890
MousePheno	abnormal conotruncus morphology	SOX4 SHROOM3 TBX1	2.38e-04	18	96	3	MP:0010583
MousePheno	abnormal muscle physiology	TBX3 PNPLA2 SHROOM3 HCN4 PPP1R13L CBL RTN2 JARID2 ARID1B MTMR14 COQ9 CACNA1H PAX7 OLIG2 ABHD12 AGRN TBX1	2.43e-04	954	96	17	MP:0002106
MousePheno	abnormal eye size	SOX1 TBX3 FRAS1 SHROOM3 AMN PPP1R13L SOCS7 MMP14 TBX1 FOXC1	2.48e-04	375	96	10	MP:0002697
MousePheno	abnormal branching involved in ureteric bud morphogenesis	FRAS1 DCHS1 MMP14 FOXD1	2.51e-04	45	96	4	MP:0010981
MousePheno	midline facial cleft	SHROOM3 SP8 CDK13	2.81e-04	19	96	3	MP:0000108
MousePheno	abnormal heart septum morphology	SOX4 TBX3 PNPLA2 FRAS1 SHROOM3 PPP1R13L JARID2 DCHS1 TBX1 FOXC1	3.26e-04	388	96	10	MP:0006113
Domain	Tim17	TIMM17B TIMM17A	3.56e-05	2	112	2	IPR005678
Domain	Groucho_enhance	TLE1 TLE4	3.52e-04	5	112	2	IPR009146
Domain	PLPL	PNPLA2 PNPLA4	3.52e-04	5	112	2	IPR033562
Domain	TLE_N	TLE1 TLE4	3.52e-04	5	112	2	PF03920
Domain	Groucho/TLE_N	TLE1 TLE4	3.52e-04	5	112	2	IPR005617
Domain	Znf_RING_CS	MKRN1 TRIM39 CBL TRIM33 TRIM67 SH3RF3	4.50e-04	163	112	6	IPR017907
Domain	PET	PRICKLE4 PRICKLE2	5.26e-04	6	112	2	PF06297
Domain	BRK	CHD9 CHD6	5.26e-04	6	112	2	SM00592
Domain	PET_domain	PRICKLE4 PRICKLE2	5.26e-04	6	112	2	IPR010442
Domain	BRK_domain	CHD9 CHD6	5.26e-04	6	112	2	IPR006576
Domain	PET	PRICKLE4 PRICKLE2	5.26e-04	6	112	2	PS51303
Domain	BRK	CHD9 CHD6	5.26e-04	6	112	2	PF07533
Domain	ZF_UBR	UBR4 UBR5	7.34e-04	7	112	2	PS51157
Domain	ApoL	APOLD1 APOL3	7.34e-04	7	112	2	IPR008405
Domain	zf-UBR	UBR4 UBR5	7.34e-04	7	112	2	PF02207
Domain	Ski_Sno	DACH1 SKOR2	7.34e-04	7	112	2	PF02437
Domain	-	DACH1 SKOR2	7.34e-04	7	112	2	3.10.260.20
Domain	Transform_Ski	DACH1 SKOR2	7.34e-04	7	112	2	IPR003380
Domain	Znf_UBR	UBR4 UBR5	7.34e-04	7	112	2	IPR003126
Domain	ApoL	APOLD1 APOL3	7.34e-04	7	112	2	PF05461
Domain	ZnF_UBR1	UBR4 UBR5	7.34e-04	7	112	2	SM00396
Domain	Tim17/Tim22/Tim23/PMP24	TIMM17B TIMM17A	9.75e-04	8	112	2	IPR003397
Domain	Tim17	TIMM17B TIMM17A	9.75e-04	8	112	2	PF02466
Domain	Patatin/PLipase_A2-rel	PNPLA2 PNPLA4	1.25e-03	9	112	2	IPR002641
Domain	Patatin	PNPLA2 PNPLA4	1.25e-03	9	112	2	PF01734
Domain	PNPLA	PNPLA2 PNPLA4	1.25e-03	9	112	2	PS51635
Domain	Sp1_fam	SP8 SP9	1.55e-03	10	112	2	IPR030450
Domain	DNA-bd_dom_put	DACH1 SKOR2	1.89e-03	11	112	2	IPR009061
Domain	Bbox_C	TRIM33 TRIM67	3.56e-03	15	112	2	IPR003649
Domain	-	JARID2 ARID1B	3.56e-03	15	112	2	1.10.150.60
Domain	BBC	TRIM33 TRIM67	3.56e-03	15	112	2	SM00502
Domain	BRIGHT	JARID2 ARID1B	3.56e-03	15	112	2	SM00501
Domain	ARID_dom	JARID2 ARID1B	3.56e-03	15	112	2	IPR001606
Domain	ARID	JARID2 ARID1B	3.56e-03	15	112	2	PS51011
Domain	ARID	JARID2 ARID1B	3.56e-03	15	112	2	PF01388
Domain	TF_T-box	TBX3 TBX1	4.57e-03	17	112	2	IPR001699
Domain	TBOX	TBX3 TBX1	4.57e-03	17	112	2	SM00425
Domain	TF_T-box_CS	TBX3 TBX1	4.57e-03	17	112	2	IPR018186
Domain	-	TBX3 TBX1	4.57e-03	17	112	2	2.60.40.820
Domain	TBOX_3	TBX3 TBX1	4.57e-03	17	112	2	PS50252
Domain	Acyl_Trfase/lysoPLipase	PNPLA2 PNPLA4	4.57e-03	17	112	2	IPR016035
Domain	T-box	TBX3 TBX1	4.57e-03	17	112	2	PF00907
Domain	TBOX_1	TBX3 TBX1	4.57e-03	17	112	2	PS01283
Domain	TBOX_2	TBX3 TBX1	4.57e-03	17	112	2	PS01264
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SOX4 PNPLA2 FRAS1 SHROOM3 SETD1B POLG UBR4 INTS1 IRAK1 ATG2A HUWE1 NCLN ANO8 DIP2A MTMR14 TMEM259 CDK13 CENPV CACNA1H MMP14 AGRN	1.26e-10	1105	117	21	35748872
Pubmed	A census of human transcription factors: function, expression and evolution.	SOX1 SOX4 ONECUT2 TBX3 POU2F1 YBX3 IRX3 TSC22D2 HOXA11 SKOR2 SETBP1 SP9 PAX7 CAMTA1 OLIG2 TBX1 FOXC1	1.09e-08	908	117	17	19274049
Pubmed	The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.	UBR4 HUWE1 TRIM33 UBR5	1.19e-07	14	117	4	27626314
Pubmed	Deterministic and stochastic allele specific gene expression in single mouse blastomeres.	SOX1 SOX4 TBX3 MKRN1 JARID2 TLE4 TIMM17A PAX7 NOCT HDAC10 FOXC1	2.12e-07	424	117	11	21731673
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	IRF2BP2 DACH1 POU2F1 ARID1B TLE1 FOXC1	3.89e-07	83	117	6	28794006
Pubmed	The Groucho-related gene family regulates the gonadotropin-releasing hormone gene through interaction with the homeodomain proteins MSX1 and OCT1.	POU2F1 TLE1 TLE4	2.05e-06	8	117	3	16002402
Pubmed	Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons.	SOX1 SP8 SP9 OLIG2	2.34e-06	28	117	4	30796806
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	SOX4 ONECUT2 TBX3 IRX3 HOXA11 SP8 SKOR2 SP9 PAX7 OLIG2 TBX1	2.42e-06	544	117	11	28473536
Pubmed	The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.	TBX3 YBX3 IRX3 HOXA11 JARID2 SP8 FOXD1	4.02e-06	191	117	7	24146773
Pubmed	Quantitative single-cell live imaging links HES5 dynamics with cell-state and fate in murine neurogenesis.	SOX1 PAX7 OLIG2	4.38e-06	10	117	3	31249377
Pubmed	EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells.	EZHIP JARID2 SUZ12	4.38e-06	10	117	3	31451685
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	TBX3 UBR4 INTS1 CHD9 TRIM33 UBR5 CHD6 FOXC1	5.38e-06	282	117	8	23667531
Pubmed	Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways.	SOX1 SOX4 SP8 TLE4 SP9 OLIG2	5.41e-06	130	117	6	19386638
Pubmed	Human transcription factor protein interaction networks.	SOX4 IRF2BP2 ZNF703 UBR4 NUMA1 DACH1 IRAK1 POU2F1 YBX3 TRIM33 ARID1B TLE1 TLE4 SP9 CHD6 PAX7 FOXC1	6.05e-06	1429	117	17	35140242
Pubmed	Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways.	SOX1 SOX4 SP8 TLE4 SP9 OLIG2	6.44e-06	134	117	6	19030180
Pubmed	Foxp1 regulates cardiac outflow tract, endocardial cushion morphogenesis and myocyte proliferation and maturation.	SOX4 IRX3 FOXC1	7.98e-06	12	117	3	15342473
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRAS1 SETD1B UBR5 TLE4 SIPA1L1 CACNA1H CHD6 SUZ12 CAMTA1	1.02e-05	407	117	9	12693553
Pubmed	c-Cbl mediates ubiquitination, degradation, and down-regulation of human protease-activated receptor 2.	CBL F2RL1	1.12e-05	2	117	2	15708858
Pubmed	SLC25A28 Overexpression Promotes Adipogenesis by Reducing ATGL.	PNPLA2 SLC25A28	1.12e-05	2	117	2	38736904
Pubmed	Combinatorial expression patterns of individual TLE proteins during cell determination and differentiation suggest non-redundant functions for mammalian homologs of Drosophila Groucho.	TLE1 TLE4	1.12e-05	2	117	2	9572356
Pubmed	The POU2F1-ALDOA axis promotes the proliferation and chemoresistance of colon cancer cells by enhancing glycolysis and the pentose phosphate pathway activity.	POU2F1 ALDOA	1.12e-05	2	117	2	34997215
Pubmed	Zeppo1 is a novel metastasis promoter that represses E-cadherin expression and regulates p120-catenin isoform expression and localization.	ZNF703 TLE4	1.12e-05	2	117	2	21317240
Pubmed	Deficiency of skeletal muscle Agrin contributes to the pathogenesis of age-related sarcopenia in mice.	PAX7 AGRN	1.12e-05	2	117	2	38461287
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	UBR4 CHD9 HUWE1 DIP2A TMEM131	1.17e-05	87	117	5	12465718
Pubmed	Molecular characterization of the mouse superior lateral parabrachial nucleus through expression of the transcription factor Runx1.	TLE1 TLE4 PAX7	1.31e-05	14	117	3	21085653
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	UBR4 HUWE1 CBL TRIM33 UBR5	1.80e-05	95	117	5	29643511
Pubmed	Sp8 plays a supplementary role to Pax6 in establishing the pMN/p3 domain boundary in the spinal cord.	SP8 PAX7 OLIG2	2.01e-05	16	117	3	24948600
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHROOM3 HCN4 UBR4 NUMA1 HUWE1 TRIM67 INA CAMKV UBR5 TMEM259 SIPA1L1 DCHS1 AGRN	2.26e-05	963	117	13	28671696
Pubmed	Calcium handling precedes cardiac differentiation to initiate the first heartbeat.	SOX1 HCN4 CACNA1H	2.44e-05	17	117	3	27725084
Pubmed	Functional dissection of the Pax6 paired domain: Roles in neural tube patterning and peripheral nervous system development.	SOX1 SP8 OLIG2	2.44e-05	17	117	3	26187199
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	INTS1 NUMA1 HUWE1 JARID2 TRIM33 CDK13 CENPV CHD6 SUZ12	3.12e-05	469	117	9	27634302
Pubmed	Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas.	EZHIP SUZ12	3.36e-05	3	117	2	29909548
Pubmed	Loss of ephrin B2 receptor (EPHB2) sets lipid rheostat by regulating proteins DGAT1 and ATGL inducing lipid droplet storage in prostate cancer cells.	EPHB2 PNPLA2	3.36e-05	3	117	2	33824421
Pubmed	The closely related transcription factors Sox4 and Sox11 function as survival factors during spinal cord development.	SOX4 OLIG2	3.36e-05	3	117	2	20646169
Pubmed	Trim33 (Tif1γ) is not required for skeletal muscle development or regeneration but suppresses cholecystokinin expression.	TRIM33 PAX7	3.36e-05	3	117	2	31811178
Pubmed	Tle corepressors are differentially partitioned to instruct CD8+ T cell lineage choice and identity.	TLE1 TLE4	3.36e-05	3	117	2	30045946
Pubmed	Sox4 mediates Tbx3 transcriptional regulation of the gap junction protein Cx43.	SOX4 TBX3	3.36e-05	3	117	2	21538160
Pubmed	UBR E3 ligases and the PDIA3 protease control degradation of unfolded antibody heavy chain by ERAD.	UBR4 UBR5	3.36e-05	3	117	2	32558906
Pubmed	EZHIP/CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma.	EZHIP SUZ12	3.36e-05	3	117	2	30923826
Pubmed	PRDM14 ensures naive pluripotency through dual regulation of signaling and epigenetic pathways in mouse embryonic stem cells.	JARID2 SUZ12	3.36e-05	3	117	2	23333148
Pubmed	Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members.	PNPLA2 PNPLA4	3.36e-05	3	117	2	16150821
Pubmed	CD56 expression in human myeloma cells derived from the neurogenic gene expression: possible role of the SRY-HMG box gene, SOX4.	SOX1 SOX4	3.36e-05	3	117	2	20049565
Pubmed	A comparative study of human GS2, its paralogues, and its rat orthologue.	PNPLA2 PNPLA4	3.36e-05	3	117	2	17603008
Pubmed	Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival.	TLE1 TLE4	3.36e-05	3	117	2	18258796
Pubmed	Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3.	SOX4 IRX3	3.36e-05	3	117	2	20080751
Pubmed	Cortical Neural Stem Cell Lineage Progression Is Regulated by Extrinsic Signaling Molecule Sonic Hedgehog.	SP8 SP9 OLIG2	3.46e-05	19	117	3	32234482
Pubmed	MOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndrome.	TBX3 TBX1 FOXC1	4.06e-05	20	117	3	22921202
Pubmed	Mir-17-3p controls spinal neural progenitor patterning by regulating Olig2/Irx3 cross-repressive loop.	IRX3 PAX7 OLIG2	4.06e-05	20	117	3	21338882
Pubmed	Single cell enhancer activity distinguishes GABAergic and cholinergic lineages in embryonic mouse basal ganglia.	DACH1 TLE4 SP9 OLIG2	4.19e-05	57	117	4	35377797
Pubmed	Global gene expression analysis of murine limb development.	TBX3 IRX3 CBL HOXA11 PAX7	4.91e-05	117	117	5	22174793
Pubmed	Homozygous Ft embryos are affected in floor plate maintenance and ventral neural tube patterning.	IRX3 PAX7 OLIG2	5.45e-05	22	117	3	15789444
Pubmed	Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity.	IRX3 PAX7 OLIG2	5.45e-05	22	117	3	12435629
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	UBR4 HUWE1 JARID2 TRIM33 GARIN3 ARID1B UBR5 SUZ12	6.10e-05	396	117	8	26687479
Pubmed	CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism.	EZHIP JARID2 SUZ12	6.26e-05	23	117	3	31281901
Pubmed	miR-30a inhibits androgen-independent growth of prostate cancer via targeting MYBL2, FOXD1, and SOX4.	SOX4 FOXD1	6.70e-05	4	117	2	32294305
Pubmed	TLE expression correlates with mouse embryonic segmentation, neurogenesis, and epithelial determination.	TLE1 TLE4	6.70e-05	4	117	2	8645603
Pubmed	A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.	UBR4 UBR5	6.70e-05	4	117	2	16055722
Pubmed	Human TBX1 missense mutations cause gain of function resulting in the same phenotype as 22q11.2 deletions.	TBX3 TBX1	6.70e-05	4	117	2	17273972
Pubmed	TRIM26 promotes non-small cell lung cancer survival by inducing PBX1 degradation.	UBR4 HUWE1	6.70e-05	4	117	2	37324936
Pubmed	Lgl1 Is Required for Olfaction and Development of Olfactory Bulb in Mice.	SP8 LLGL1	6.70e-05	4	117	2	27603780
Pubmed	Planar cell polarity-dependent asymmetric organization of microtubules for polarized positioning of the basal body in node cells.	PRICKLE2 DCHS1	6.70e-05	4	117	2	35420656
Pubmed	Hoxa 11 is upstream of Integrin alpha8 expression in the developing kidney.	HOXA11 FOXD1	6.70e-05	4	117	2	12060755
Pubmed	The substrate recognition domains of the N-end rule pathway.	UBR4 UBR5	6.70e-05	4	117	2	19008229
Pubmed	Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube.	TLE1 TLE4	6.70e-05	4	117	2	11290324
Pubmed	Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities.	PNPLA2 PNPLA4	6.70e-05	4	117	2	15364929
Pubmed	A genomic atlas of mouse hypothalamic development.	EPHB2 SOX4 SIPA1L1 OLIG2 NOVA1 FOXD1	7.08e-05	205	117	6	20436479
Pubmed	Sonic hedgehog signaling controls thalamic progenitor identity and nuclei specification in mice.	SOX1 PAX7 OLIG2	8.08e-05	25	117	3	19357274
Pubmed	Wnt signaling determines ventral spinal cord cell fates in a time-dependent manner.	IRX3 PAX7 OLIG2	8.08e-05	25	117	3	18927156
Pubmed	Loss of Gsx1 and Gsx2 function rescues distinct phenotypes in Dlx1/2 mutants.	SP8 SP9 OLIG2	8.08e-05	25	117	3	23042297
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SHROOM3 UBR4 NUMA1 ATG2A TSC22D2 SETBP1 PAX7 CAMTA1	1.08e-04	430	117	8	35044719
Pubmed	Rescuing Z+ agrin splicing in Nova null mice restores synapse formation and unmasks a physiologic defect in motor neuron firing.	AGRN NOVA1	1.11e-04	5	117	2	19221030
Pubmed	Functional redundancy between human SHOX and mouse Shox2 genes in the regulation of sinoatrial node formation and pacemaking function.	TBX3 HCN4	1.11e-04	5	117	2	21454626
Pubmed	Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins.	TLE1 TLE4	1.11e-04	5	117	2	1303260
Pubmed	Loss of PRMT5 Promotes PDGFRα Degradation during Oligodendrocyte Differentiation and Myelination.	CBL OLIG2	1.11e-04	5	117	2	30057274
Pubmed	Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer.	TBX1 FOXC1	1.11e-04	5	117	2	12533514
Pubmed	Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development.	TBX3 TBX1	1.11e-04	5	117	2	8853987
Pubmed	Activity-Based Probes for HECT E3 Ubiquitin Ligases.	HUWE1 UBR5	1.11e-04	5	117	2	28425671
Pubmed	Lipid droplet dynamics regulate adult muscle stem cell fate.	PNPLA2 PAX7	1.11e-04	5	117	2	35045287
Pubmed	Sp8 and Sp9, two closely related buttonhead-like transcription factors, regulate Fgf8 expression and limb outgrowth in vertebrate embryos.	SP8 SP9	1.11e-04	5	117	2	15358670
Pubmed	Membralin deficiency dysregulates astrocytic glutamate homeostasis leading to ALS-like impairment.	TMEM259 OLIG2	1.11e-04	5	117	2	31112137
Pubmed	Embryonic Tbx3+ cardiomyocytes form the mature cardiac conduction system by progressive fate restriction.	TBX3 HCN4	1.11e-04	5	117	2	30042181
Pubmed	Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein.	TLE1 TLE4	1.11e-04	5	117	2	8365415
Pubmed	Epigenetic mechanisms of Groucho/Grg/TLE mediated transcriptional repression.	TLE4 SUZ12	1.11e-04	5	117	2	22169276
Pubmed	A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes.	SOX1 SOX4	1.11e-04	5	117	2	2374589
Pubmed	Grg3, a murine Groucho-related gene, is expressed in the developing nervous system and in mesenchyme-induced epithelial structures.	TLE1 TLE4	1.11e-04	5	117	2	8989517
Pubmed	Non-coding RNA Neat1 and Abhd11os expressions are dysregulated in medium spiny neurons of Huntington disease model mice.	SMIM10L2A SMIM10L2B	1.11e-04	5	117	2	30391555
Pubmed	Genetic variance in the adiponutrin gene family and childhood obesity.	PNPLA2 PNPLA4	1.11e-04	5	117	2	19390624
Pubmed	Cul3-KLHL20 E3 ubiquitin ligase plays a key role in the arms race between HIV-1 Nef and host SERINC5 restriction.	UBR4 HUWE1 UBR5	1.14e-04	28	117	3	35474067
Pubmed	The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development.	SP8 SP9 FOXD1	1.14e-04	28	117	3	32868762
Pubmed	Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components.	IRX3 PAX7 OLIG2	1.27e-04	29	117	3	21209331
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	ABI3 TTC9B UBR4 F2RL1 ANO8 LLGL1 TMEM259 CACNA1H SLC25A28 ABHD12	1.28e-04	697	117	10	28298427
Pubmed	Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.	EPHB2 SOX1 FRAS1 SP8 SLC19A1 MMP14 TBX1	1.35e-04	331	117	7	20634891
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	HUWE1 LLGL1 UBR5 SIPA1L1 SUZ12 FOXC1	1.39e-04	232	117	6	25515538
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SHROOM3 POLG CHD9 HUWE1 ANO8 TMCO4 CDK13 SLC19A1 SETBP1 CACNA1H TTC17 CHD6 CAMTA1 SH3RF3 FAM149A	1.45e-04	1489	117	15	28611215
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	UBR4 DACH1 POU2F1 HUWE1 TRIM33 UBR5 TLE1 TLE4 FOXC1 NOVA1 FOXD1	1.55e-04	857	117	11	25609649
Pubmed	Wnt/β-catenin signaling maintains the mesenchymal precursor pool for murine sinus horn formation.	TBX3 HCN4 TBX1	1.56e-04	31	117	3	21757651
Pubmed	Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry.	IRAK1 TRIM39 YBX3 CBL	1.58e-04	80	117	4	16094384
Pubmed	Chromosomal localization of six human forkhead genes, freac-1 (FKHL5), -3 (FKHL7), -4 (FKHL8), -5 (FKHL9), -6 (FKHL10), and -8 (FKHL12).	FOXC1 FOXD1	1.67e-04	6	117	2	8825632
Pubmed	Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2.	JARID2 SUZ12	1.67e-04	6	117	2	27892467
Pubmed	Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network.	HCN4 IRX3	1.67e-04	6	117	2	21825130
Interaction	PAX7 interactions	ZNF703 DACH1 POU2F1 ARID1B TLE1 TLE4 CHD6 PAX7 FOXC1	3.29e-08	124	113	9	int:PAX7
Interaction	SP7 interactions	IRF2BP2 ZNF703 POU2F1 CBL TRIM33 ARID1B TLE1 TLE4 SP9 FOXC1	8.30e-06	304	113	10	int:SP7
Interaction	TLE3 interactions	IRF2BP2 ZNF703 TBX3 CBL ARID1B UBR5 TLE1 TLE4 CHD6 PAX7 FOXC1	8.75e-06	376	113	11	int:TLE3
Interaction	GSC interactions	ZNF703 TBX3 POU2F1 ARID1B TLE1 TLE4	9.49e-06	87	113	6	int:GSC
Interaction	FOXI1 interactions	ZNF703 TRIM33 ARID1B TLE1 TLE4 FOXC1	1.31e-05	92	113	6	int:FOXI1
Interaction	FEV interactions	ZNF703 DACH1 POU2F1 ARID1B TLE1 TLE4 CHD6 FOXC1	1.91e-05	203	113	8	int:FEV
Interaction	TOP3B interactions	SOX4 PNPLA2 FRAS1 SHROOM3 SETD1B POLG UBR4 INTS1 IRAK1 ATG2A HUWE1 NCLN ANO8 DIP2A SAFB MTMR14 TMEM259 CDK13 CENPV CACNA1H MMP14 AGRN	1.94e-05	1470	113	22	int:TOP3B
Interaction	BANF1 interactions	EPHB2 SOX4 NUMA1 POU2F1 HUWE1 CBL TRIM67 CDK13	1.98e-05	204	113	8	int:BANF1
Interaction	RHOT1 interactions	IRAK1 HUWE1 ASB14 TRIM67 COQ9	3.71e-05	67	113	5	int:RHOT1
Interaction	ERG interactions	ZNF703 UBR4 NUMA1 HUWE1 TRIM33 ARID1B UBR5 TLE1	3.74e-05	223	113	8	int:ERG
Interaction	VASP interactions	IRF2BP2 SHROOM3 ABI3 UBR4 IRAK1 CBL TRIM67 SIPA1L1 APBB1IP	4.20e-05	294	113	9	int:VASP
Interaction	BAG2 interactions	IRF2BP2 ZNF703 POLG IRAK1 POU2F1 HUWE1 PPP1R13L CBL TRIM33 LLGL1 TRIM67 TLE4 FOXC1	4.62e-05	622	113	13	int:BAG2
Interaction	TBXT interactions	IRF2BP2 ZNF703 ARID1B TLE1 TLE4 FOXC1	4.89e-05	116	113	6	int:TBXT
Interaction	TLX1 interactions	IRF2BP2 ZNF703 DACH1 ARID1B TLE1 TLE4 FOXC1	5.88e-05	175	113	7	int:TLX1
Interaction	UBTD1 interactions	SHROOM3 TRIM39 ATG2A TRIM67	7.33e-05	40	113	4	int:UBTD1
Interaction	ADI1 interactions	TRIM67 TRAPPC14 ALDOA MMP14	9.77e-05	43	113	4	int:ADI1
GeneFamily	Prickle planar cell polarity proteins\|LIM domain containing	PRICKLE4 PRICKLE2	1.07e-04	4	77	2	1184
GeneFamily	Ubiquitin protein ligase E3 component n-recognins	UBR4 UBR5	3.71e-04	7	77	2	785
GeneFamily	Zinc fingers C2H2-type\|Sp transcription factors	SP8 SP9	6.32e-04	9	77	2	755
GeneFamily	Patatin like phospholipase domain containing	PNPLA2 PNPLA4	7.88e-04	10	77	2	466
GeneFamily	Ring finger proteins	MKRN1 TRIM39 CBL TRIM33 TRIM67 SH3RF3	1.13e-03	275	77	6	58
GeneFamily	AT-rich interaction domain containing	JARID2 ARID1B	1.81e-03	15	77	2	418
GeneFamily	T-boxes	TBX3 TBX1	2.62e-03	18	77	2	766
GeneFamily	SRY-boxes	SOX1 SOX4	2.92e-03	19	77	2	757
GeneFamily	Solute carriers	SLC39A12 SLC19A1 SLC2A13 SLC25A28 SLC4A11 SLC25A31	6.74e-03	395	77	6	752
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM39 TRIM33 TRIM67	7.76e-03	95	77	3	59
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3	SOX1 ONECUT2 TBX3 SHROOM3 HCN4 IRX3 F2RL1 SP8 INA RGS9BP SP9 TACR3 MMP14 OLIG2 SLC4A11 FOXC1 FOXD1	5.74e-06	1074	117	17	M1941
Coexpression	XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_UP	EPHB2 F2RL1 FOXD1	2.40e-05	13	117	3	M17359
Coexpression	KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3	IRF2BP2 ZNF703 TBX3 POLG CHD9 TSC22D2 PPP1R13L CBL F2RL1 TMEM259 TLE1 SETBP1 SLC25A28 SLC4A11	2.44e-05	843	117	14	M2356
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	EPHB2 CHD9 TSC22D2 JARID2 TRIM33 UBR5 CDK13 TLE1 TLE4 SIPA1L1 TMEM131 KAZN SUZ12 FOXD1	2.88e-05	856	117	14	M4500
Coexpression	GSE3982_EOSINOPHIL_VS_MAC_UP	POU2F1 MAPKAPK5-AS1 JARID2 MTMR14 UBR5 CDK13 OLIG2	3.01e-05	197	117	7	M5401
Coexpression	GSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN	AMN TTC9B SLC39A12 LLGL1 MTMR14 SIPA1L1 SUZ12	3.21e-05	199	117	7	M9846
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	CHD9 JARID2 TRIM33 UBR5 CDK13 TLE1 TLE4 TMEM131 SUZ12 FOXD1	4.69e-05	466	117	10	M13522
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_DN	TBX3 HCN4 POLG GPR135 MAPKAPK5-AS1 ATG2A NCLN RTN2 TMEM259 SLC19A1 TLE4 TIMM17A CACNA1H TBX1	5.52e-05	909	117	14	M41018
Coexpression	BENPORATH_SUZ12_TARGETS	SOX1 ONECUT2 ZNF703 TBX3 AMN HCN4 DACH1 IRX3 TRIM67 INA RGS9BP PAX7 OLIG2 TBX1 APBB1IP	5.86e-05	1035	117	15	M9898
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000	EPHB2 TBX3 DACH1 IRAK1 POU2F1 RTN2 SP8 SAFB INA UBR5 TLE4 SETBP1 SP9 CHD6 SUZ12 TRAPPC14 OLIG2 SH3RF3 NOVA1	1.53e-06	983	116	19	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05	EPHB2 SOX1 ZNF703 IFI27L2 SHROOM3 PCDHGB6 PCDHGA11 SMIM10L2A NUMA1 DACH1 IRX3 ANO8 SP8 TLE4 CACNA1H TTC17 HDAC10 SLC25A28 AGRN	5.61e-06	1075	116	19	PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500	SHROOM3 IRAK1 POU2F1 YBX3 RTN2 JARID2 INA TLE4 OLIG2 SH3RF3 NOVA1 FOXD1	1.73e-05	495	116	12	Facebase_RNAseq_e8.5_Floor Plate_500
CoexpressionAtlas	kidney_P0_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_500	SHROOM3 DACH1 FOXC1 FOXD1	2.37e-05	31	116	4	gudmap_kidney_P0_CapMes_Crym_k3_500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#2	SETD1B DACH1 IRAK1 RTN2 LLGL1 UBR5 TLE4 OLIG2 ZNF367 NOVA1	6.27e-05	395	116	10	Facebase_RNAseq_e8.5_Floor Plate_2500_K2
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#1	SHROOM3 RTN2 INA TLE4 SP9 ZNF367	7.05e-05	127	116	6	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K1
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_500	IRF2BP2 AMN SPINK1 DACH1 HUWE1 F2RL1 SUZ12 AGRN FOXC1 FOXD1	7.25e-05	402	116	10	gudmap_developingKidney_e15.5_anlage of loop of Henle_500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500	SHROOM3 POU2F1 IRX3 RTN2 JARID2 SP8 INA SP9 PAX7 ALDOA NOVA1	8.75e-05	496	116	11	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500	EPHB2 DACH1 POU2F1 IRX3 SAFB INA UBR5 OLIG2 ZNF367 NOVA1 FOXD1	9.06e-05	498	116	11	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000	SHROOM3 INTS1 DACH1 IRAK1 POU2F1 YBX3 RTN2 JARID2 INA UBR5 TLE4 OLIG2 SH3RF3 ZNF367 NOVA1 FOXD1	1.01e-04	994	116	16	Facebase_RNAseq_e8.5_Floor Plate_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#1	IRAK1 POU2F1 SP8 INA TLE4	2.02e-04	98	116	5	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K1
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_100	IRX3 SP8 INA SP9 PAX7	2.02e-04	98	116	5	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_100
CoexpressionAtlas	kidney_P0_CapMes_Crym_top-relative-expression-ranked_500	SHROOM3 SPINK1 DACH1 HOXA11 SIPA1L1 CENPV FOXC1 FOXD1	2.14e-04	294	116	8	gudmap_kidney_P0_CapMes_Crym_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	EPHB2 DACH1 IRAK1 SAFB UBR5 TLE4 SETBP1 COQ9 CHD6 SUZ12 TRAPPC14 NOVA1	2.44e-04	654	116	12	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlas	kidney_P0_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_1000	SHROOM3 DACH1 FOXC1 FOXD1	2.86e-04	58	116	4	gudmap_kidney_P0_CapMes_Crym_k4_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000	SHROOM3 POU2F1 RTN2 JARID2 SP8 DIP2A INA SETBP1 PRICKLE2 SP9 CACNA1H OLIG2 SH3RF3 ZNF367 NOVA1	3.10e-04	986	116	15	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000
CoexpressionAtlas	DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_top-relative-expression-ranked_200	TDRD5 AMN DACH1 AGRN FOXC1 FOXD1	3.14e-04	167	116	6	gudmap_developingKidney_e15.5_stage III -IV renal corpusc_200
CoexpressionAtlas	kidney_P3_CapMes_Crym_k-means-cluster#1_top-relative-expression-ranked_1000	SHROOM3 YBX3 HOXA11 SIPA1L1 SETBP1 CENPV CAMTA1	3.20e-04	236	116	7	gudmap_kidney_P3_CapMes_Crym_k1_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000	TIMM17B SHROOM3 POU2F1 YBX3 IRX3 RTN2 JARID2 SP8 INA TLE4 SP9 PAX7 ALDOA ZNF367 NOVA1	3.27e-04	991	116	15	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#1	IRAK1 POU2F1 INA FOXD1	3.47e-04	61	116	4	Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K1
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	SOX1 ZNF703 IFI27L2 SHROOM3 PCDHGB6 PCDHGA11 NUMA1 DACH1 IRX3 PPP1R13L ANO8 SP8 DIP2A TLE4 CACNA1H TTC17 HDAC10 SLC25A28 AGRN	3.63e-04	1466	116	19	PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
CoexpressionAtlas	dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_200	TTC9B RTN2 INA	4.22e-04	27	116	3	gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k2_200
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX4 ONECUT2 TTC9B INA CAMKV SP9 CENPV NOVA1	5.31e-08	197	117	8	47c4d9de71a435119c71f5219de836cf9b2aab6d
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 ZNF703 JPH2 YBX3 IRX3 CDK13 FOXC1	6.94e-07	189	117	7	965e0e388251e7318f8b463816dc96ccb4658677
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Immature_INs\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	SOX1 SOX4 POU2F1 TSC22D2 SP8 ARID1B SP9	7.19e-07	190	117	7	842760bfe0a52e67bad800efa7d99448a4a23ebb
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	TBX3 FRAS1 SPINK1 JARID2 ARID1B UBR5 CHD6	7.71e-07	192	117	7	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 SHROOM3 DACH1 ARID1B SIPA1L1 SETBP1 PRICKLE2	7.71e-07	192	117	7	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	TBX3 FRAS1 SPINK1 JARID2 ARID1B UBR5 CHD6	7.98e-07	193	117	7	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Neuronal\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	SOX4 TTC9B RTN2 SP8 INA CAMKV SP9	9.47e-07	198	117	7	076c862f2a723f0361749377561cae902068b1a0
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	SOX1 HCN4 SP8 TRIM67 CHD6 SLC2A13	4.01e-06	159	117	6	7f29f9dcf25ffa1822b137c571e9ac16defc6292
ToppCell	facs-Aorta-Heart-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX1 SHROOM3 AMN SPINK1 JPH2 PAX7	5.69e-06	169	117	6	daed9083ee05c220365200328c2c50047fe21efd
ToppCell	Control\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SOX4 TBX3 FRAS1 DACH1 PRICKLE2 NOVA1	7.42e-06	177	117	6	b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_A2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	EPHB2 PRICKLE4 SETD1B TMCO4 TLE1 SIPA1L1	8.17e-06	180	117	6	62511d76d24b836839c3dcc2bf30485ffe9401e2
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF703 JPH2 YBX3 IRX3 CDK13 FOXC1	9.84e-06	186	117	6	bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD5 FRAS1 F2RL1 SLC4A11 FOXC1 FOXD1	1.01e-05	187	117	6	806075c2531a7f5c1da38b85ea494a3b4b5e92ec
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX4 TTC9B INA CAMKV CENPV NOVA1	1.01e-05	187	117	6	85645de9069bd9a8a02d53b0d3d73bf9c2b57189
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ONECUT2 TBX3 HCN4 TTC9B TRIM67 INA	1.05e-05	188	117	6	bd091503f580dedab40e0996273101285d24b586
ToppCell	LV-14._Fibroblast_III\|World / Chamber and Cluster_Paper	EPHB2 JARID2 TLE1 PRICKLE2 KAZN SLC2A13	1.08e-05	189	117	6	3922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCell	IPF-Myeloid-ncMonocyte\|Myeloid / Disease state, Lineage and Cell class	ZNF703 ABI3 TLE4 SIPA1L1 SETBP1 NOCT	1.08e-05	189	117	6	5c22d2d935f7bb270260b8bc6be67b565ec401bf
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 F2RL1 AGRN SLC4A11 FOXC1 FOXD1	1.11e-05	190	117	6	050d6e0546954675b6adbfecb67854b1e09739d1
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TBX3 FRAS1 DACH1 TLE4 PRICKLE2 NOVA1	1.11e-05	190	117	6	474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 IRX3 KAZN SLC2A13 SLC4A11 FOXC1	1.14e-05	191	117	6	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron\|World / Primary Cells by Cluster	SOX1 SOX4 IFI27L2 CHD9 SP8 SP9	1.14e-05	191	117	6	4dd9c8117c4499ed9bde127baf2598603a82080d
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-SST-MGE1\|World / Primary Cells by Cluster	SOX1 SOX4 IFI27L2 CHD9 SP8 SP9	1.18e-05	192	117	6	bcc499f4c7ba2898ecd9c47bf68c92ed359b81ba
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-CFuPNs\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	SOX4 TTC9B INA CAMKV TLE4 KAZN	1.18e-05	192	117	6	a8841ebd879f1c344ab4246fdef77044170f644d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX4 ZNF703 IRX3 SLC2A13 SLC4A11 FOXC1	1.21e-05	193	117	6	0f2167eef8203a5659c8c72e4e77646003d64797
ToppCell	LA-14._Fibroblast_III\|LA / Chamber and Cluster_Paper	YBX3 ARID1B PRICKLE2 KAZN SLC2A13 NOVA1	1.21e-05	193	117	6	7426c291bac59e539c427bcaae18abc7d397d44e
ToppCell	TCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma\|TCGA-Adrenal / Sample_Type by Project: Shred V9	ZNF703 TBX3 SMIM10L2A NCLN TMCO4 COQ9	1.21e-05	193	117	6	c0d4da15d973cf6f8daa2b0af84b1baaf8491b83
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX4 ONECUT2 INA CAMKV SP9 CENPV	1.25e-05	194	117	6	4e93bd903cddfd0c8f220b6a35b449895de4119b
ToppCell	LA-14._Fibroblast_III\|World / Chamber and Cluster_Paper	YBX3 ARID1B PRICKLE2 KAZN SLC2A13 NOVA1	1.25e-05	194	117	6	803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX4 TTC9B INA CENPV OLIG2 NOVA1	1.33e-05	196	117	6	fe2dd3a93fe22da93e24a400e154a68757985fc8
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TBX3 JPH2 APOLD1 CACNA1H AGRN FOXC1	1.33e-05	196	117	6	73f029d2b276776d6c24356b14c6592c9cb74bd5
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M\|organoid_Kanton_Nature / Sample Type, Dataset, Time_group, and Cell type.	SOX4 IRX3 CAMKV TLE4 KAZN NOVA1	1.36e-05	197	117	6	86157ba4f9a40a80bab2404684fe5a7b4ee380c5
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX4 ONECUT2 TTC9B CAMKV SP9 NOVA1	1.36e-05	197	117	6	b4554353c56e220bae31ee3c8aa222674dd0b18c
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_2\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	SOX4 TTC9B SP8 INA CAMKV SP9	1.40e-05	198	117	6	b73b9feb82997b654718aa27f33ca7b454214802
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Neuronal\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	SOX4 TTC9B SP8 INA CAMKV SP9	1.49e-05	200	117	6	7534005613ee22aee2bac51070929957dece3c8b
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Neuronal-Intermediate\|1m / Sample Type, Dataset, Time_group, and Cell type.	SOX4 TTC9B DACH1 TLE1 TBX1 NOVA1	1.49e-05	200	117	6	805f50236113713b02f77aa5e208efb3b3b959d5
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Interneuron\|6m / Sample Type, Dataset, Time_group, and Cell type.	SOX4 ONECUT2 TTC9B INA SP9 CENPV	1.49e-05	200	117	6	274871d632bbbe03720726a59ab3ec6d5fa0da11
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Neuronal-Interneuron\|1m / Sample Type, Dataset, Time_group, and Cell type.	SOX4 ONECUT2 HCN4 TTC9B INA NOVA1	1.49e-05	200	117	6	fc839e9c33ea1d4ee0f42f21fd32a54e7cbe1f5a
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	UBR4 POU2F1 JARID2 TRIM33 UBR5	2.89e-05	135	117	5	3351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	SOX1 HCN4 SP8 TRIM67 SLC2A13	3.32e-05	139	117	5	408bc31aa5e1c2b379f79198fe8b5411f8d7bd08
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SETD1B SPINK1 CBL SLC39A12 DCHS1	3.93e-05	144	117	5	5e948d4cb913ccd8f82262a1b4d20967aadab3ab
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF703 TTC9B IRX3 SLC2A13 SLC4A11	4.07e-05	145	117	5	8da10bc6611976e1ec85e09f04a2dc5bf6555c9e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 SHROOM3 SMIM10L2A DACH1 OLIG2	6.30e-05	159	117	5	50d951cf27a571c0c5002003c16fbc370fa17eb1
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SOX1 UBR5 SP9 CHD6 SLC2A13	6.69e-05	161	117	5	b81b346309f3facbfbebd91cae4c5b33c7bd24ef
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	CHD9 YBX3 TLE1 SIPA1L1 SETBP1	7.09e-05	163	117	5	6bed27d2f67a430a847da5eb47878d14b4949c45
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC39A12 APOLD1 TMEM131 SLC25A28 TBX1	7.51e-05	165	117	5	50a8513d8d2630861499393a7f102b35366bad37
ToppCell	10x5'-blood-Lymphocytic_NK-NK_CD56bright_CD16-\|blood / Manually curated celltypes from each tissue	FRAS1 PPP1R13L TLE1 KAZN FOXC1	7.73e-05	166	117	5	ba42349a68b22e91a0340bda1ccecd6c7592392f
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SOX4 SPINK1 IRAK1 NCLN DIP2A	7.95e-05	167	117	5	d1a13d6ada572d8ddb2da95e6e122d2b705fad7f
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231\|Adult / Lineage, Cell type, age group and donor	TBX3 DACH1 APOL3 PRICKLE2 SH3RF3	7.95e-05	167	117	5	5af9127bae05768a5164d5708a4ad37edca99324
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IRX3 APOL3 DCHS1 SH3RF3 ZNF367	8.18e-05	168	117	5	37249f38f8f04ec5743097259de67b106ca2b02f
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SOX1 SP8 SP9 CHD6 SLC2A13	8.41e-05	169	117	5	c135d7ae0490d0024e0f4bd8c4ad42f6674a61da
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD5 TBX3 PCDHGA11 PRICKLE2 FOXD1	8.41e-05	169	117	5	87116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell	Frontal_cortex-Neuronal-Inhibitory\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	SOX1 TRIM67 SP9 CHD6 SLC2A13	8.41e-05	169	117	5	78eb70dd916724e476eabccf18fb7fcec4210308
ToppCell	PND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLG LLGL1 APOLD1 TBX1 FOXC1	9.39e-05	173	117	5	03b50b2376d353748a32bf14a9fc8341ea61dbca
ToppCell	PND28-Endothelial-Endothelial_lymphatic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLG LLGL1 APOLD1 TBX1 FOXC1	9.39e-05	173	117	5	2978c744d3c8dcaa2b9bb225abf846f82e8f9176
ToppCell	PND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLG LLGL1 APOLD1 TBX1 FOXC1	9.39e-05	173	117	5	12da47b90aecedaa31764ff7ddb853ee39123e9d
ToppCell	PND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POLG LLGL1 APOLD1 TBX1 FOXC1	9.39e-05	173	117	5	23d4a315a0ad5c6fc77bcfc18b6c1ff55be99e8f
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 PCDHGB6 PCDHGA11 TMEM131 FOXD1	9.64e-05	174	117	5	268be5e7d2a18b866770b7cdb966c3958c7e6534
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX4 PCDHGB6 PCDHGA11 TMEM131 FOXD1	9.64e-05	174	117	5	4cdf2eedc28d88d18241ee390092426fdf849e79
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB2 SOX4 CAMKV TMEM131 KAZN	9.64e-05	174	117	5	b2fc2a756f8e373ad903bd416d9de703d945fa1c
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JPH2 CAMKV RGS9BP TMEM131 KAZN	1.02e-04	176	117	5	d43d9e86c4d4fa1e88fbf2b899ac7143717aac90
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TDRD5 ONECUT2 SPINK1 CAMKV TRAPPC14	1.05e-04	177	117	5	43dce527392f3b8364bb6a55268ce9d6518d3a29
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte-2\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ONECUT2 IRX3 F2RL1 SLC4A11 FOXC1	1.05e-04	177	117	5	8f0873d348f37c823294b698043319b6608b678a
ToppCell	Striatum-Endothelial-MURAL\|Striatum / BrainAtlas - Mouse McCarroll V32	TBX3 APOLD1 SLC19A1 FOXC1 FOXD1	1.10e-04	179	117	5	3d58babf44e47462c3d4129dd2e94a2339fd7ce0
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)\|Striatum / BrainAtlas - Mouse McCarroll V32	TBX3 APOLD1 SLC19A1 FOXC1 FOXD1	1.10e-04	179	117	5	99167ac678cae5c35b1d4f4a81b32000437c00c2
ToppCell	Control-Endothelial_cells-Capillary_endothelial_cells\|Control / group, cell type (main and fine annotations)	TBX3 DACH1 APOL3 PRICKLE2 SH3RF3	1.13e-04	180	117	5	b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SOX4 FRAS1 SHROOM3 SOCS7 FAM149A	1.13e-04	180	117	5	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Alv_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TBX3 FRAS1 DACH1 TLE4 NOVA1	1.13e-04	180	117	5	544fb373a3346186ec60afe2cfcf141bb04a1eed
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	IRX3 HOXA11 SLC39A12 PLAAT2 MMP14	1.16e-04	181	117	5	46c428037b6eac605635e20e8cc78bce744b4daa
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX4 TTC9B INA CENPV NOVA1	1.19e-04	182	117	5	fa23d5bed1147a423c42bd30029a06963410b16e
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_A2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	EPHB2 PRICKLE4 SETD1B TMCO4 SIPA1L1	1.19e-04	182	117	5	03992d0ae519795239e4f2cc8e63f33c4482de6a
ToppCell	Hippocampus-Neuronal-Inhibitory\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SOX1 UBR5 SP9 CHD6 SLC2A13	1.19e-04	182	117	5	b54ae650c04dfd0759c5f5e752b9bf684dd36516
ToppCell	wk_20-22-Hematologic-Myeloid-Basophil\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PNPLA2 UBR4 RTN2 TRAPPC14 OLIG2	1.22e-04	183	117	5	93d821d5340caed0eef455d3d738be213ce5fff8
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX4 TTC9B SP9 CENPV NOVA1	1.22e-04	183	117	5	af14da45267261e775dd6dab7a4c359b181e46f1
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD5 TBX3 SLC39A12 PRICKLE2 FOXD1	1.22e-04	183	117	5	f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCell	Neuron-Postmitotic-Inhibitory_Neuron-SST-MGE1-3\|World / Primary Cells by Cluster	SOX1 SOX4 IFI27L2 SP8 SP9	1.25e-04	184	117	5	907ba412166bcb0526c5be0b06a76b6bd37c5a35
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DACH1 RTN2 APOLD1 CDK13 DCHS1	1.32e-04	186	117	5	2cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPP1R13L F2RL1 SETBP1 DCHS1 FOXC1	1.32e-04	186	117	5	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DACH1 RTN2 APOLD1 CDK13 DCHS1	1.32e-04	186	117	5	90d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX1 ONECUT2 CAMKV SP9 FOXD1	1.32e-04	186	117	5	bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCell	Adult-Endothelial-endothelial_cell_of_artery\|Adult / Lineage, Cell type, age group and donor	DACH1 SETBP1 APOL3 TBX1 FOXC1	1.32e-04	186	117	5	2d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ONECUT2 HCN4 INA TBX1 FAM149A	1.32e-04	186	117	5	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	Control-Endothelial-Endothelial-Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TBX3 FRAS1 DACH1 TLE4 PRICKLE2	1.35e-04	187	117	5	ea9d34bcd3bd1f36745846309ede349773de501a
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 TTC9B TRIM67 INA CAMKV	1.35e-04	187	117	5	a748b3a59e398e0da019db3f16d38adb1960c29f
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TBX3 DACH1 JPH2 TLE1 CACNA1H	1.35e-04	187	117	5	86250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	DACH1 JARID2 TLE4 PRICKLE2 SH3RF3	1.35e-04	187	117	5	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX4 ZNF703 IRX3 SLC4A11 FOXC1	1.35e-04	187	117	5	9225caf66e06ebe57e90d677122acb6498607f36
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	YBX3 ARID1B TLE1 SIPA1L1 SETBP1	1.39e-04	188	117	5	d8decd9b5967873ca8320c2f9f07365f163c777f
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TBX3 DACH1 TLE4 PRICKLE2 NOVA1	1.39e-04	188	117	5	789d1be574e693d7bdd488f3c72c6df788e47b47
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ONECUT2 HCN4 INA TBX1 FAM149A	1.39e-04	188	117	5	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB2 SHROOM3 F2RL1 SLC2A13 SLC4A11	1.39e-04	188	117	5	14e120b20e76baa07b6510a94f0c2dcdfdd52357
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 DACH1 UBR5 TLE4 PRICKLE2	1.39e-04	188	117	5	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TBX3 DACH1 APOL3 PRICKLE2 SH3RF3	1.42e-04	189	117	5	b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB2 SHROOM3 F2RL1 SLC2A13 SLC4A11	1.42e-04	189	117	5	443359d90fafae0c1de6bdcce9e8c95df6ea4de8
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TBX3 TTC9B TRIM67 INA SKOR2	1.42e-04	189	117	5	cceca3d14dd559bbb2cb4b81ea12c2b62d18ee49
ToppCell	COPD-Myeloid-ncMonocyte\|Myeloid / Disease state, Lineage and Cell class	ZNF703 ABI3 TLE4 SIPA1L1 SETBP1	1.46e-04	190	117	5	ed978cd5d9da87b49878a330e362762c487f849f
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB2 SHROOM3 F2RL1 SLC2A13 FOXC1	1.46e-04	190	117	5	c247562df3e1aa3173c9f01a74d5831f0764a1b2
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX4 TTC9B CENPV OLIG2 NOVA1	1.46e-04	190	117	5	a28e14fff75c36b1a8634eaf3f305e3206fdc2ed
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHB2 SHROOM3 F2RL1 SLC2A13 FOXC1	1.46e-04	190	117	5	5cea8298c8336c136ba009630c9e48d4bc832cb2
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX4 TTC9B INA SP9 CENPV	1.46e-04	190	117	5	b4dfc41f5a630140cab8b1b86de85de0f5b25e4a
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TBX3 DACH1 TLE4 PRICKLE2 NOVA1	1.46e-04	190	117	5	106ea0bb7b99c697ffc5443d72343df2484250c7
Computational	Neighborhood of NUMA1	NUMA1 CHD9 SAFB TTC17 TRAPPC14	2.24e-05	56	66	5	GCM_NUMA1
Drug	Muramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A	EPHB2 SOX4 NUMA1 PPP1R13L RTN2 JARID2 CACNA1H AGRN	7.15e-06	193	117	8	3262_UP
Drug	Metyrapone [54-36-4]; Up 200; 17.6uM; HL60; HT_HG-U133A	EPHB2 ONECUT2 PCDHGB6 TSC22D2 PPP1R13L SOCS7 LLGL1 INA	8.00e-06	196	117	8	3070_UP
Drug	Glibenclamide [10238-21-8]; Up 200; 8uM; HL60; HG-U133A	EPHB2 FRAS1 LLGL1 CAMKV PLAAT2 TRAPPC14 AGRN FOXC1	8.00e-06	196	117	8	1546_UP
Drug	Pempidine tartrate [546-48-5]; Up 200; 13uM; MCF7; HT_HG-U133A	EPHB2 PNPLA2 CBL SOCS7 HOXA11 TLE1 CACNA1H MMP14	8.30e-06	197	117	8	3832_UP
Drug	felodipine; Up 200; 10uM; MCF7; HG-U133A	PNPLA2 HOXA11 DCHS1 PLAAT2 KAZN TRAPPC14 SLC25A28 APBB1IP	8.30e-06	197	117	8	337_UP
Drug	Ornidazole [16773-42-5]; Up 200; 18.2uM; HL60; HG-U133A	AMN POU2F1 ATG2A HOXA11 INA CAMKV TLE1 AGRN	8.94e-06	199	117	8	1425_UP
Drug	Scopolamin-N-oxide hydrobromide [6106-81-6]; Up 200; 10uM; HL60; HG-U133A	EPHB2 AMN INTS1 ATG2A JARID2 LLGL1 CAMKV AGRN	8.94e-06	199	117	8	1415_UP
Drug	irinotecan HCl; Down 200; 100uM; PC3; HT_HG-U133A	POU2F1 CHD9 JARID2 TRIM33 UBR5 CDK13 SIPA1L1	2.95e-05	171	117	7	7535_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA	SOX4 TIMM17B ATG2A TSC22D2 SLC19A1 AGRN FOXC1	4.71e-05	184	117	7	1064_DN
Drug	Withaferin A [5119-48-2]; Down 200; 1uM; MCF7; HT_HG-U133A	SOX4 ONECUT2 NUMA1 TSC22D2 CDK13 SIPA1L1 PLAAT2	5.05e-05	186	117	7	3902_DN
Drug	retinoic acid; Down 200; 1uM; HL60; HT_HG-U133A	HCN4 HOXA11 TLE1 KAZN MMP14 OLIG2 AGRN	5.58e-05	189	117	7	6170_DN
Drug	Phthalylsulfathiazole [85-73-4]; Down 200; 10uM; MCF7; HT_HG-U133A	EPHB2 DACH1 CBL TMEM259 TLE4 PLAAT2 TRAPPC14	5.77e-05	190	117	7	5614_DN
Drug	rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	EPHB2 HUWE1 RTN2 APOLD1 TLE1 CACNA1H FAM149A	6.37e-05	193	117	7	921_UP
Drug	Prednicarbate [73771-04-7]; Down 200; 8.2uM; PC3; HT_HG-U133A	EPHB2 TRIM33 APOLD1 TIMM17A TTC17 TRAPPC14 MMP14	6.37e-05	193	117	7	5119_DN
Drug	Corticosterone [50-22-6]; Down 200; 11.6uM; HL60; HT_HG-U133A	SOX4 PNPLA2 DACH1 ATG2A TSC22D2 SLC19A1 TRAPPC14	6.58e-05	194	117	7	1307_DN
Drug	Ethoxyquin [91-53-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A	EPHB2 FRAS1 CBL TLE1 TLE4 APOL3 MMP14	6.58e-05	194	117	7	3846_UP
Drug	Cephalosporanic acid, 7-amino [957-68-6]; Down 200; 14.6uM; PC3; HT_HG-U133A	PNPLA2 RTN2 TRIM33 TMEM259 CDK13 MMP14 AGRN	6.58e-05	194	117	7	4242_DN
Drug	Diphenhydramine hydrochloride [147-24-0]; Up 200; 13.8uM; PC3; HT_HG-U133A	EPHB2 GPR135 TSC22D2 SLC19A1 KAZN MMP14 TBX1	6.80e-05	195	117	7	7318_UP
Drug	Pindolol [13523-86-9]; Up 200; 16.2uM; MCF7; HT_HG-U133A	EPHB2 ONECUT2 AMN NYX TSC22D2 SLC19A1 KAZN	6.80e-05	195	117	7	6834_UP
Drug	17-DMAG; Down 200; 0.1uM; HL60; HT_HG-U133A	EPHB2 NUMA1 TSC22D2 NCLN UBR5 SLC19A1 TRAPPC14	6.80e-05	195	117	7	6172_DN
Drug	Ceforanide [60925-61-3]; Up 200; 7.6uM; HL60; HT_HG-U133A	UBR4 GPR135 HUWE1 INA CAMKV PLAAT2 FOXC1	7.02e-05	196	117	7	2447_UP
Drug	PF-00539745-00 [351321-33-0]; Down 200; 10uM; MCF7; HT_HG-U133A	EPHB2 SPINK1 NUMA1 F2RL1 SOCS7 NOCT NOVA1	7.02e-05	196	117	7	5974_DN
Drug	copper(II) sulfate pentahydrate; Down 200; 100uM; ssMCF7; HG-U133A	SOX4 ONECUT2 TBX3 AMN CBL LLGL1 SLC25A28	7.02e-05	196	117	7	500_DN
Drug	Propidium iodide [25535-16-4]; Up 200; 6uM; MCF7; HT_HG-U133A	ONECUT2 DACH1 SAFB TMEM259 SLC19A1 PLAAT2 NOCT	7.25e-05	197	117	7	6277_UP
Drug	SB 203580; Down 200; 1uM; MCF7; HT_HG-U133A	HCN4 NUMA1 DACH1 HUWE1 APOLD1 CACNA1H TRAPPC14	7.25e-05	197	117	7	7061_DN
Drug	rottlerin; Down 200; 10uM; MCF7; HT_HG-U133A_EA	CHD9 PPP1R13L DIP2A SLC19A1 TLE4 TRAPPC14 FOXC1	7.25e-05	197	117	7	825_DN
Drug	Aminocaproic acid [60-32-2]; Down 200; 30.4uM; HL60; HT_HG-U133A	UBR4 RTN2 SLC19A1 SIPA1L1 KAZN TRAPPC14 MMP14	7.25e-05	197	117	7	3122_DN
Drug	SC 19220; Down 200; 10uM; PC3; HT_HG-U133A	SOX4 POLG TSC22D2 NCLN DIP2A MTMR14 MMP14	7.49e-05	198	117	7	7095_DN
Drug	Cefadroxil [50370-12-2]; Down 200; 11uM; MCF7; HT_HG-U133A	PNPLA2 POLG DACH1 TMEM259 CDK13 TRAPPC14 SLC25A28	7.49e-05	198	117	7	3259_DN
Drug	Propantheline bromide [50-34-0]; Up 200; 9uM; PC3; HT_HG-U133A	NUMA1 RTN2 LLGL1 TMEM259 SLC19A1 TLE4 MMP14	7.49e-05	198	117	7	4214_UP
Drug	Nialamide [51-12-7]; Up 200; 13.4uM; PC3; HT_HG-U133A	AMN DACH1 HUWE1 TSC22D2 INA APOL3 TBX1	7.49e-05	198	117	7	3790_UP
Drug	Metrizamide [31112-62-6]; Down 200; 5uM; HL60; HT_HG-U133A	SOX4 PNPLA2 TSC22D2 APOLD1 SIPA1L1 TRAPPC14 MMP14	7.73e-05	199	117	7	1318_DN
Drug	Sulfasalazine [599-79-1]; Up 200; 10uM; MCF7; HT_HG-U133A	EPHB2 SPINK1 NUMA1 NYX HUWE1 SLC19A1 SETBP1	7.73e-05	199	117	7	2882_UP
Drug	Atropine-N-oxide hydrochloride [4574-60-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A	PNPLA2 DACH1 APOLD1 TMEM259 CACNA1H TRAPPC14 MMP14	7.73e-05	199	117	7	2216_DN
Drug	Acebutolol hydrochloride [34381-68-5]; Down 200; 10.8uM; PC3; HG-U133A	TBX3 MKRN1 POU2F1 PPP1R13L UBR5 AGRN NOVA1	7.73e-05	199	117	7	1911_DN
Drug	Riboflavine [83-88-5]; Up 200; 10.6uM; PC3; HT_HG-U133A	AMN DACH1 HUWE1 CBL LLGL1 APOL3 MMP14	7.73e-05	199	117	7	4485_UP
Drug	Flucloxacillin sodium [1847-24-1]; Down 200; 8.4uM; HL60; HT_HG-U133A	UBR4 GPR135 SLC19A1 SETBP1 TIMM17A TRAPPC14 FOXC1	7.73e-05	199	117	7	3128_DN
Drug	Chenodiol [474-25-9]; Up 200; 10.2uM; MCF7; HT_HG-U133A	EPHB2 HCN4 TSC22D2 CBL RTN2 CDK13 TIMM17A	7.73e-05	199	117	7	6012_UP
Disease	age at first birth measurement	AMN MKRN1 EZHIP CAMKV SIPA1L1	1.05e-04	120	114	5	EFO_0009101
Disease	Myelomonocytic leukemia	CBL SETBP1	1.47e-04	5	114	2	C0027019
Disease	Self-injurious behavior	GPR135 ARID1B KAZN NOCT	2.42e-04	78	114	4	HP_0100716
Disease	diastolic blood pressure, systolic blood pressure	TBX3 SPINK1 HCN4 GPR135 JPH2 TRIM33 SLC39A12 ARID1B SETBP1 CHD6	2.79e-04	670	114	10	EFO_0006335, EFO_0006336
Disease	CHARGE syndrome (implicated_via_orthology)	CHD9 CHD6	3.07e-04	7	114	2	DOID:0050834 (implicated_via_orthology)
Disease	Abnormality of the skeletal system	INTS1 SUZ12	4.08e-04	8	114	2	C4021790
Disease	brain volume measurement	EPHB2 FRAS1 DACH1 GPR135 SLC39A12 INA TLE1 HDAC10 CAMTA1	5.15e-04	595	114	9	EFO_0006930
Disease	epilepsy (is_implicated_in)	POLG TBX1	5.23e-04	9	114	2	DOID:1826 (is_implicated_in)
Disease	Malignant neoplasm of breast	TBX3 PCDHGB6 UBR4 POU2F1 SLC39A12 ARID1B LLGL1 INA SIPA1L1 SETBP1 ALDOA MMP14	9.29e-04	1074	114	12	C0006142
Disease	response to carboplatin, methylcobalamin deficiency type cblE, response to antineoplastic agent	APOL3 KAZN	9.52e-04	12	114	2	GO_0097327, GO_0097328, MONDO_0009354
Disease	QRS duration	UBR4 SP8 UBR5 SIPA1L1 SKOR2 SETBP1	1.08e-03	298	114	6	EFO_0005055
Disease	Coffin-Siris syndrome	SOX4 ARID1B	1.12e-03	13	114	2	C0265338
Disease	Disorder of eye	FRAS1 NYX RGS9BP ABHD12 FOXC1	1.42e-03	212	114	5	C0015397
Disease	irritable bowel syndrome symptom measurement	ARID1B TRIM67 APOLD1	1.48e-03	58	114	3	EFO_0021536
Disease	lymphocyte count	FRAS1 AMN PCDHGB6 PCDHGA11 IRAK1 JPH2 NCLN CBL JARID2 DIP2A APOLD1 CDK13 TLE4 APBB1IP	1.55e-03	1464	114	14	EFO_0004587
Disease	Tetralogy of Fallot	TBX1 FOXC1	1.71e-03	16	114	2	C0039685
Disease	Muscle hypotonia	INTS1 PAX7	1.94e-03	17	114	2	C0026827
Disease	Limb Deformities, Congenital	TBX3 HOXA11	1.94e-03	17	114	2	C0206762
Disease	ischemia (implicated_via_orthology)	ARID1B MMP14	1.94e-03	17	114	2	DOID:326 (implicated_via_orthology)
Disease	Alzheimer disease, gastroesophageal reflux disease	ABI3 PPP1R13L UBR5 CDK13 CAMTA1	1.96e-03	228	114	5	EFO_0003948, MONDO_0004975
Disease	mean platelet volume	SETD1B PCDHGB6 PCDHGA11 NUMA1 CHD9 TSC22D2 F2RL1 SP8 SETBP1 CAMTA1 ZNF367	2.01e-03	1020	114	11	EFO_0004584
Disease	Juvenile Myelomonocytic Leukemia	CBL SETBP1	2.42e-03	19	114	2	C0349639
Disease	Nonorganic psychosis	SP8 OLIG2 TBX1	2.44e-03	69	114	3	C0349204
Disease	waist-hip ratio	EPHB2 PNPLA2 HCN4 TSC22D2 F2RL1 HOXA11 TRIM33 SP8 APOLD1 SETBP1 KAZN FOXC1	2.81e-03	1226	114	12	EFO_0004343
Disease	autism spectrum disorder (implicated_via_orthology)	CHD9 ARID1B CHD6 TBX1	2.91e-03	152	114	4	DOID:0060041 (implicated_via_orthology)
Disease	Moderate albuminuria	SHROOM3 NUMA1 CAMTA1	3.72e-03	80	114	3	HP_0012594
Disease	Cleft Palate	INTS1 SLC19A1 TBX1	3.85e-03	81	114	3	C0008925

Protein segments in the cluster

Peptide	Gene	Start	Entry
EIAGAGAASVLSALT	PLAAT2	41	Q9NWW9
STATAALGAAARLAT	TDRD5	951	Q8NAT2
SAAAVAASSLTLTAG	CAMTA1	551	Q9Y6Y1
SAACSSASSLGLGLA	INA	51	Q16352
SGQAGAAASESLFVS	ALDOA	346	P04075
SASLQASIFSGAASL	APBB1IP	96	Q7Z5R6
TSGAIAAGATARATT	AGRN	1261	O00468
SSAAGLAGGVAAAVL	AMN	356	Q9BXJ7
AALKEGGSAAALSSS	ARID1B	106	Q8NFD5
ASDSSSILLEAASGG	ASB14	246	A6NK59
ASAAAAAATVTSTGG	DACH1	61	Q9UI36
TGLTAAAAAAAAATN	DACH1	321	Q9UI36
GLLLGGASAATAATA	CDK13	156	Q14004
AASFGSSTASAALEL	ATG2A	1786	Q2TAZ0
SGATSSLAAAGAGAT	ANO8	991	Q9HCE9
LTLGTALASLGSAQS	MMP14	16	P50281
GVAGASSGVAARALS	RGS9BP	116	Q6ZS82
AAAASSVSSSAALGT	FOXD1	431	Q16676
LASASEAADGSSTLG	PCDHGA11	856	Q9Y5H2
AASASQGSASAAEVL	NCLN	161	Q969V3
LASASEAADGSSTLG	PCDHGB6	851	Q9Y5F9
QGGLAAAAAAADTSS	PAX7	336	P23759
AASDIAALGTEGSSV	LLGL1	146	Q15334
AAAGSSSSGSAAAAL	ABHD12	16	Q8N2K0
SSAFSLASAGSAEGV	ABI3	206	Q9P2A4
ANVAGSSLSATGALA	APOLD1	86	Q96LR9
SSLSATGALAAIVGL	APOLD1	91	Q96LR9
GAADAGNLSASVTVS	DCHS1	2786	Q96JQ0
ASAGALTATALVTGV	PNPLA2	46	Q96AD5
GASDAASTASLGEAA	JPH2	256	Q9BR39
VAASLSQTGASIGSA	FRAS1	3891	Q86XX4
GAAASASAAGDSAAT	KAZN	51	Q674X7
ATLQSVGAAGLSTSS	IFI27L2	61	Q9H2X8
AAAALSSASALTGLT	INTS1	61	Q8N201
GSAASRAAGAVGTLL	FAM149A	81	A5PLN7
AAAAAASAGSSASSG	MTMR14	6	Q8NCE2
GSSAAAATSAAIFIT	EZHIP	66	Q86X51
LSGAESTSLVAARGS	EPHB2	211	P29323
GASAGSLVASVLLTA	PNPLA4	41	P41247
LGTAAAAAAAASRSA	ONECUT2	91	O95948
LSGACAGAVAAAATT	SLC25A28	266	Q96A46
AATATSAAAAAAATG	HOXA11	171	P31270
AVEGLALGSSASSSS	IRAK1	641	P51617
LASLAAAGSGTDAQV	HUWE1	2136	Q7Z6Z7
ALALLSLSGNTGADS	SPINK1	11	P00995
AAGGTESRSSALGAA	HCN4	61	Q9Y3Q4
SLVSAAAASAGNSAP	POU2F1	691	P14859
SLALSNATGLSADGG	PRICKLE2	546	Q7Z3G6
ATLSRTLLAAAGGSS	PRICKLE4	241	Q2TBC4
GAAILLAASLSCSGT	F2RL1	11	P55085
LANLASGGAAGATSL	SLC25A31	126	Q9H0C2
SGIAKATAAAAAASA	CHD9	2636	Q3L8U1
ATAAAAAASATSVSG	CHD9	2641	Q3L8U1
NSGIAATPASAAAAT	HDAC10	476	Q969S8
TVATAALGNLSDASG	GPR135	46	Q8IZ08
AGGATAAAASGATSA	CAMKV	351	Q8NCB2
LGAGRTSALSASTLA	CHD6	266	Q8TD26
AELSSGLLASAAASS	FOXC1	326	Q12948
GLLASAAASSRAGIA	FOXC1	331	Q12948
SGASAAPAASAAAAL	CENPV	21	Q7Z7K6
SLALTAAGVGLGAAS	APOL3	216	O95236
SSLVAAAASVAAAAG	TMEM259	521	Q4ZIN3
SASAGGSRLAAAAAA	MAPKAPK5-AS1	66	Q8N8E1
GLSSAGSLSASFQLS	C2orf81	216	A6NN90
SSASALGTASKAASG	CBL	511	P22681
IAEGAQSLGLSSAAA	COQ9	121	O75208
SAAATPGAAATTALA	DIP2A	196	Q14689
ATAAASLRLATGLGT	CACNA1H	596	O95180
GLAIGAAFSSSSESG	SLC39A12	556	Q504Y0
GAAIFATTLSDGATA	PPP1R13L	716	Q8WUF5
GGRAAASLAAVSGTA	IRF2BP2	206	Q7Z5L9
ASLAAVSGTAAASLG	IRF2BP2	211	Q7Z5L9
LLAAASAASGAARSC	NOCT	46	Q9UK39
ATTTASAATAAAIGA	NUMA1	2091	Q14980
AAAPSTGSSAKGLAA	JARID2	271	Q92833
LGAGASELNASGSLS	IRX3	36	P78415
LSQAAATGALAAAAA	NOVA1	336	P51513
GTFALGSLAAATAAT	NOVA1	381	P51513
ATTSGAGAAAATAAA	MKRN1	11	Q9UHC7
GLANASLSDSLSSRG	NYX	436	Q9GZU5
STVGAAAVSALAGGA	SLC2A13	126	Q96QE2
AGAASLSQDSSLSAA	GARIN3	361	Q8TC56
GTGALASAAAAVSGS	RTN2	526	O75298
ATAASAAASAILGGR	POLG	71	A0A3B3IS91
SSLVSLSGLGASLNA	SLC4A11	516	Q8NBS3
ASSAASASAALAAPG	SOX4	271	Q06945
GVAAASSGSAQAASS	TRIM33	66	Q9UPN9
LLEAGASAASTAAAL	TRIM39	6	Q9HCM9
MASAAAAQGLSGASA	TBX3	561	O15119
TIIGSAGAAALGSAA	TMCO4	221	Q5TGY1
RSVSGALASTLAAAA	TSC22D2	111	O75157
TGASAAAVASLVSGP	SIPA1L1	361	O43166
ALSAAAAAAALSGLA	SMIM10L2A	6	P0DMW4
ALSAAAAAAALSGLA	SMIM10L2B	6	P0DMW5
AALEGSGLASASSLS	SHROOM3	1126	Q8TF72
VTAVAGATAAFRGSS	SETD1B	336	Q9UPS6
AAAAAAAVSSASLPG	OLIG2	231	Q13516
AAAAAASSGALGALG	SOX1	301	O00570
AVNLTASLAAGAATG	TACR3	21	P29371
AAAAAAGGSSARSAR	SP9	286	P0CG40
SGAAGAAALSSASSE	SAFB	11	Q15424
RNGGSSSAAAAAAAA	SP8	61	Q8IXZ3
GSSAAAARGAACSSL	TRIM67	136	Q6ZTA4
SAGLLALSSALSGQS	TLE1	161	Q04724
SGLGSAAAAAAAAAS	ZNF703	501	Q9H7S9
APAATGTAAAASLAT	YBX3	61	P16989
GTAAAASLATAAGSE	YBX3	66	P16989
ATALAALASVSAGGG	TRAPPC14	76	Q8WVR3
SAGLLALSSALGGQS	TLE4	166	Q04727
FLSAAAGSTAGSLRE	SH3RF3	166	Q8TEJ3
SSSSAAAAAGAAVLP	SUZ12	56	Q15022
NGAADAASTLLGAIT	SLC19A1	306	P41440
AASTLLGAITSFAAG	SLC19A1	311	P41440
GATTAAVSTSAGAGL	TMEM131	11	Q92545
SALLSVAARGAFATT	TTC17	26	Q96AE7
VTAKAGGGTSAAAAS	nan	6	Q8N1X5
LAASAASLTDMGGSA	SOCS7	241	O14512
AAAASLSVAAASGGA	SKOR2	331	Q2VWA4
NSITSGALTGAVLAA	TIMM17B	91	O60830
NSITSGALTGAILAA	TIMM17A	91	Q99595
EAFTASSLSSLGAAG	TBX1	11	O43435
TLSPGAAGAAASAAL	ZNF367	81	Q7RTV3
ISSATAAALLSSGAV	UBR4	3081	Q5T4S7
KVLAALAASSGSSSA	UBR4	3331	Q5T4S7
LAASAATSDAVGSSL	SETBP1	1381	Q9Y6X0
SGSLGAALDSSLRAA	TTC9B	51	Q8N6N2
SVVTAATAGSEAGAS	UBR5	1641	O95071
GTISTSAAAAAAALE	UBR5	1756	O95071
LVGSFSASLAGTSNL	LEG1	11	Q6P5S2