Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	N-CoR_GPS2_interact	NCOR1 NCOR2	5.42e-06	2	44	2	IPR031557
Domain	GPS2_interact	NCOR1 NCOR2	5.42e-06	2	44	2	PF15784
Domain	HMGI/Y_DNA-bd_CS	PRR12 PSIP1 YTHDC1	5.24e-05	31	44	3	IPR000637
Domain	SANT_dom	NCOR1 NCOR2	1.70e-03	26	44	2	IPR017884
Domain	SANT	NCOR1 NCOR2	1.97e-03	28	44	2	PS51293
Domain	Ank	ANKRD30B MPHOSPH8 GPANK1 NFKB2	2.00e-03	228	44	4	PF00023
Domain	-	ANKRD30B MPHOSPH8 GPANK1 NFKB2	2.72e-03	248	44	4	1.25.40.20
Domain	ANK	ANKRD30B MPHOSPH8 GPANK1 NFKB2	2.84e-03	251	44	4	SM00248
Domain	ANK_REPEAT	ANKRD30B MPHOSPH8 GPANK1 NFKB2	2.92e-03	253	44	4	PS50088
Domain	Ankyrin_rpt-contain_dom	ANKRD30B MPHOSPH8 GPANK1 NFKB2	2.96e-03	254	44	4	IPR020683
Domain	ANK_REP_REGION	ANKRD30B MPHOSPH8 GPANK1 NFKB2	2.96e-03	254	44	4	PS50297
Domain	Myb_DNA-binding	NCOR1 NCOR2	3.07e-03	35	44	2	PF00249
Domain	Ankyrin_rpt	ANKRD30B MPHOSPH8 GPANK1 NFKB2	3.31e-03	262	44	4	IPR002110
Domain	P-loop_NTPase	SMARCA2 DLG1 MCM3 MYO3A GNAS DNAH10 TK2	3.42e-03	848	44	7	IPR027417
Domain	MYB_LIKE	NCOR1 NCOR2	3.61e-03	38	44	2	PS50090
Domain	SANT	NCOR1 NCOR2	6.18e-03	50	44	2	SM00717
Domain	SANT/Myb	NCOR1 NCOR2	6.67e-03	52	44	2	IPR001005
Domain	-	SMARCA2 DLG1 MCM3 GNAS DNAH10 TK2	7.70e-03	746	44	6	3.40.50.300
Pathway	REACTOME_LOSS_OF_MECP2_BINDING_ABILITY_TO_THE_NCOR_SMRT_COMPLEX	NCOR1 NCOR2	8.53e-05	7	29	2	M27899
Pathway	WP_RETT_SYNDROME	SMARCA2 NCOR1 NCOR2	1.27e-04	48	29	3	M39759
Pathway	REACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_CONTROL_BILE_ACID_HOMEOSTASIS	NCOR1 NCOR2	1.46e-04	9	29	2	M29809
Pathway	REACTOME_LOSS_OF_FUNCTION_OF_MECP2_IN_RETT_SYNDROME	NCOR1 NCOR2	3.14e-04	13	29	2	M29766
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SMARCA2 TATDN2 DLG1 NCOR1 MCM3 NCOR2 MYO3A PSIP1 YTHDC1 ARGLU1 SCAF8	4.06e-09	774	46	11	15302935
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SMARCA2 MAK16 LENG8 PRR12 DLG1 MPHOSPH8 ZNF326 UBXN4 RPL7L1 YTHDC1 ARGLU1 SCAF8 SMG6	4.46e-08	1497	46	13	31527615
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	MAK16 DLG1 MCM3 ZNF326 GNAS RPL7L1 PSIP1 SNRPA YTHDC1 ARGLU1 SPTBN2	5.49e-07	1257	46	11	36526897
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	SMARCA2 CASP8AP2 NCOR1 MCM3 NCOR2 MPHOSPH8 PSIP1 SNRPA YTHDC1 ARGLU1	6.67e-07	1014	46	10	32416067
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	PRR12 CASP8AP2 NCOR1 NCOR2 MPHOSPH8 ZNF326 RPL7L1 PSIP1 SNRPA YTHDC1 ARGLU1	7.30e-07	1294	46	11	30804502
Pubmed	Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.	SMARCA2 NCOR1 NCOR2	1.45e-06	17	46	3	19183483
Pubmed	TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.	MAK16 ZNF326 GNAS RPL7L1 PSIP1 SNRPA YTHDC1	1.49e-06	430	46	7	38172120
Pubmed	Aberrant corepressor interactions implicated in PML-RAR(alpha) and PLZF-RAR(alpha) leukemogenesis reflect an altered recruitment and release of specific NCoR and SMRT splice variants.	NCOR1 NCOR2	1.71e-06	2	46	2	21131350
Pubmed	Regulation of corepressor alternative mRNA splicing by hormonal and metabolic signaling.	NCOR1 NCOR2	1.71e-06	2	46	2	26166430
Pubmed	Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways.	NCOR1 NCOR2	1.71e-06	2	46	2	19299558
Pubmed	Unique forms of human and mouse nuclear receptor corepressor SMRT.	NCOR1 NCOR2	1.71e-06	2	46	2	10077563
Pubmed	NCoR/SMRT co-repressors cooperate with c-MYC to create an epigenetic barrier to somatic cell reprogramming.	NCOR1 NCOR2	1.71e-06	2	46	2	29531310
Pubmed	CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas.	NCOR1 NCOR2	1.71e-06	2	46	2	27733359
Pubmed	PCSK6 exacerbates Alzheimer's disease pathogenesis by promoting MT5-MMP maturation.	MMP24 PCSK6	1.71e-06	2	46	2	38216110
Pubmed	Nuclear Receptor Corepressors NCOR1 and SMRT Regulate Metabolism via Intestinal Regulation of Carbohydrate Transport.	NCOR1 NCOR2	1.71e-06	2	46	2	39106294
Pubmed	Corepressors (NCoR and SMRT) as well as coactivators are recruited to positively regulated 1α,25-dihydroxyvitamin D3-responsive genes.	NCOR1 NCOR2	1.71e-06	2	46	2	22944139
Pubmed	Evolution of NCoR-1 and NCoR-2 corepressor alternative mRNA splicing in placental mammals.	NCOR1 NCOR2	1.71e-06	2	46	2	31208445
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	SMARCA2 LENG8 PRR12 NCOR1 NCOR2 ZNF326 SCAF8	2.22e-06	457	46	7	32344865
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	MCM3 ZNF326 GNAS RPL7L1 PSIP1 SNRPA YTHDC1 ARGLU1 SPTBN2	3.59e-06	949	46	9	36574265
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	LENG8 NCOR1 MCM3 NCOR2 MPHOSPH8 ZNF326 PSIP1 SNRPA ARGLU1	3.75e-06	954	46	9	36373674
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	SMARCA2 PRR12 NCOR1 NCOR2	4.56e-06	83	46	4	28794006
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	MAK16 LENG8 MCM3 NCOR2 MPHOSPH8 ZNF326 RPL7L1 YTHDC1 NFKB2	5.02e-06	989	46	9	36424410
Pubmed	Functional interactions with Pit-1 reorganize co-repressor complexes in the living cell nucleus.	NCOR1 NCOR2	5.13e-06	3	46	2	16030140
Pubmed	Nuclear Receptor CoRepressors, NCOR1 and SMRT, are required for maintaining systemic metabolic homeostasis.	NCOR1 NCOR2	5.13e-06	3	46	2	34390859
Pubmed	Oligomerization of ETO is obligatory for corepressor interaction.	NCOR1 NCOR2	5.13e-06	3	46	2	11113190
Pubmed	Involvement of SMRT corepressor in transcriptional repression by the vitamin D receptor.	NCOR1 NCOR2	5.13e-06	3	46	2	19098224
Pubmed	The corepressors silencing mediator of retinoid and thyroid hormone receptor and nuclear receptor corepressor are involved in agonist- and antagonist-regulated transcription by androgen receptor.	NCOR1 NCOR2	5.13e-06	3	46	2	16373395
Pubmed	Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action.	NCOR1 NCOR2	5.13e-06	3	46	2	31404087
Pubmed	RU486-induced glucocorticoid receptor agonism is controlled by the receptor N terminus and by corepressor binding.	NCOR1 NCOR2	5.13e-06	3	46	2	12011091
Pubmed	EBV nuclear antigen EBNALP dismisses transcription repressors NCoR and RBPJ from enhancers and EBNA2 increases NCoR-deficient RBPJ DNA binding.	NCOR1 NCOR2	5.13e-06	3	46	2	21518914
Pubmed	Regulated clearance of histone deacetylase 3 protects independent formation of nuclear receptor corepressor complexes.	NCOR1 NCOR2	5.13e-06	3	46	2	22337871
Pubmed	Cell cycle progression stimulated by tamoxifen-bound estrogen receptor-alpha and promoter-specific effects in breast cancer cells deficient in N-CoR and SMRT.	NCOR1 NCOR2	5.13e-06	3	46	2	15802375
Pubmed	SMRT and NCoR1 fine-tune inflammatory versus tolerogenic balance in dendritic cells by differentially regulating STAT3 signaling.	NCOR1 NCOR2	5.13e-06	3	46	2	36238311
Pubmed	The nuclear receptor corepressor N-CoR regulates differentiation: N-CoR directly interacts with MyoD.	NCOR1 NCOR2	5.13e-06	3	46	2	10406466
Pubmed	Nuclear corepressors NCOR1/NCOR2 regulate B cell development, maintain genomic integrity and prevent transformation.	NCOR1 NCOR2	5.13e-06	3	46	2	36316474
Pubmed	Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo.	NCOR1 NCOR2	5.13e-06	3	46	2	23292142
Pubmed	The functional relationship between co-repressor N-CoR and SMRT in mediating transcriptional repression by thyroid hormone receptor alpha.	NCOR1 NCOR2	5.13e-06	3	46	2	18052923
Pubmed	Equilibrium interactions of corepressors and coactivators with agonist and antagonist complexes of glucocorticoid receptors.	NCOR1 NCOR2	5.13e-06	3	46	2	15016838
Pubmed	The transcription factor B-Myb is maintained in an inhibited state in target cells through its interaction with the nuclear corepressors N-CoR and SMRT.	NCOR1 NCOR2	5.13e-06	3	46	2	11997503
Pubmed	Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor.	NCOR1 NCOR2	5.13e-06	3	46	2	24268577
Pubmed	Structural basis for nuclear receptor corepressor recruitment by antagonist-liganded androgen receptor.	NCOR1 NCOR2	5.13e-06	3	46	2	18852122
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	SMARCA2 MAK16 NCOR1 MCM3 ZNF326 RPL7L1 SNRPA YTHDC1 ARGLU1 SCAF8	6.93e-06	1318	46	10	30463901
Pubmed	MicroRNAs are mediators of androgen action in prostate and muscle.	NCOR1 NCOR2	1.03e-05	4	46	2	21048966
Pubmed	Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint.	NCOR1 NCOR2	1.03e-05	4	46	2	19595715
Pubmed	Aberrant recruitment of the nuclear receptor corepressor-histone deacetylase complex by the acute myeloid leukemia fusion partner ETO.	NCOR1 NCOR2	1.03e-05	4	46	2	9819405
Pubmed	Vitamin D-dependent recruitment of corepressors to vitamin D/retinoid X receptor heterodimers.	NCOR1 NCOR2	1.03e-05	4	46	2	18362166
Pubmed	Silencing mediator for retinoid and thyroid hormone receptor and nuclear receptor corepressor attenuate transcriptional activation by the beta-catenin-TCF4 complex.	NCOR1 NCOR2	1.03e-05	4	46	2	18632669
Pubmed	Boat, an AXH domain protein, suppresses the cytotoxicity of mutant ataxin-1.	NCOR1 NCOR2	1.03e-05	4	46	2	16121196
Pubmed	Dichotomous engagement of HDAC3 activity governs inflammatory responses.	NCOR1 NCOR2	1.03e-05	4	46	2	32760002
Pubmed	A selective peroxisome proliferator-activated receptor-gamma modulator, telmisartan, binds to the receptor in a different fashion from thiazolidinediones.	NCOR1 NCOR2	1.03e-05	4	46	2	19147680
Pubmed	A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation.	NCOR1 NCOR2	1.03e-05	4	46	2	12840002
Pubmed	A cell type-specific expression map of NCoR1 and SMRT transcriptional co-repressors in the mouse brain.	NCOR1 NCOR2	1.03e-05	4	46	2	32072640
Pubmed	NCoR1 and SMRT play unique roles in thyroid hormone action in vivo.	NCOR1 NCOR2	1.03e-05	4	46	2	25421714
Pubmed	Transcriptional activity of Sp1 is regulated by molecular interactions between the zinc finger DNA binding domain and the inhibitory domain with corepressors, and this interaction is modulated by MEK.	NCOR1 NCOR2	1.03e-05	4	46	2	15878880
Pubmed	FBI-1 functions as a novel AR co-repressor in prostate cancer cells.	NCOR1 NCOR2	1.03e-05	4	46	2	20812024
Pubmed	Direct association between the CREB-binding protein (CBP) and nuclear receptor corepressor (N-CoR).	NCOR1 NCOR2	1.03e-05	4	46	2	17073437
Pubmed	The integrity of the charged pocket in the BTB/POZ domain is essential for the phenotype induced by the leukemia-associated t(11;17) fusion protein PLZF/RARalpha.	NCOR1 NCOR2	1.03e-05	4	46	2	16024608
Pubmed	The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3.	NCOR1 NCOR2	1.03e-05	4	46	2	11509652
Pubmed	Nuclear receptor coregulator SNP discovery and impact on breast cancer risk.	NCOR1 NCOR2	1.03e-05	4	46	2	20003447
Pubmed	A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor.	NCOR1 NCOR2	1.03e-05	4	46	2	20543827
Pubmed	GR SUMOylation and formation of an SUMO-SMRT/NCoR1-HDAC3 repressing complex is mandatory for GC-induced IR nGRE-mediated transrepression.	NCOR1 NCOR2	1.03e-05	4	46	2	26712002
Pubmed	Glucocorticoid-induced tethered transrepression requires SUMOylation of GR and formation of a SUMO-SMRT/NCoR1-HDAC3 repressing complex.	NCOR1 NCOR2	1.03e-05	4	46	2	26712006
Pubmed	The retinoid X receptor binding to the thyroid hormone receptor: relationship with cofactor binding and transcriptional activity.	NCOR1 NCOR2	1.03e-05	4	46	2	19211732
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	MCM3 MPHOSPH8 ZNF326 PSIP1 FAM32A SNRPA YTHDC1 ARGLU1 SPTBN2	1.03e-05	1082	46	9	38697112
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	SMARCA2 NCOR1 MCM3 NCOR2 ZNF326	1.07e-05	220	46	5	35785414
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	SMARCA2 NCOR2 ZNF326 GNAS SNRPA ARGLU1 SCAF8	1.08e-05	582	46	7	20467437
Pubmed	Human transcription factor protein interaction networks.	SMARCA2 LENG8 PRR12 NCOR1 NCOR2 ZNF326 RPL7L1 DNAH10 SCAF8 NFKB2	1.40e-05	1429	46	10	35140242
Pubmed	Combinatorial roles of the nuclear receptor corepressor in transcription and development.	NCOR1 NCOR2	1.71e-05	5	46	2	11030619
Pubmed	Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction.	NCOR1 NCOR2	1.71e-05	5	46	2	29033129
Pubmed	Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor.	NCOR1 NCOR2	1.71e-05	5	46	2	7566114
Pubmed	ERbeta Binds N-CoR in the Presence of Estrogens via an LXXLL-like Motif in the N-CoR C-terminus.	NCOR1 NCOR2	1.71e-05	5	46	2	12904255
Pubmed	Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma.	NCOR1 NCOR2	1.71e-05	5	46	2	15175761
Pubmed	The POZ/BTB protein NAC1 interacts with two different histone deacetylases in neuronal-like cultures.	NCOR1 NCOR2	1.71e-05	5	46	2	16033423
Pubmed	Involvement of the SMRT/NCoR-HDAC3 complex in transcriptional repression by the CNOT2 subunit of the human Ccr4-Not complex.	NCOR1 NCOR2	1.71e-05	5	46	2	16712523
Pubmed	Antiandrogen effects of mifepristone on coactivator and corepressor interactions with the androgen receptor.	NCOR1 NCOR2	1.71e-05	5	46	2	14593076
Pubmed	Critical residues within the BTB domain of PLZF and Bcl-6 modulate interaction with corepressors.	NCOR1 NCOR2	1.71e-05	5	46	2	11865059
Pubmed	The histone-binding code of nuclear receptor co-repressors matches the substrate specificity of histone deacetylase 3.	NCOR1 NCOR2	1.71e-05	5	46	2	15832170
Pubmed	Targeting fusion protein/corepressor contact restores differentiation response in leukemia cells.	NCOR1 NCOR2	1.71e-05	5	46	2	15729358
Pubmed	Expression of nuclear receptor corepressors and class I histone deacetylases in astrocytic gliomas.	NCOR1 NCOR2	1.71e-05	5	46	2	21143702
Pubmed	The histone deacetylase-3 complex contains nuclear receptor corepressors.	NCOR1 NCOR2	1.71e-05	5	46	2	10860984
Pubmed	A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness.	NCOR1 NCOR2	1.71e-05	5	46	2	10809664
Pubmed	Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection.	NCOR1 NCOR2	1.71e-05	5	46	2	30664766
Pubmed	Epigenetic control of a VDR-governed feed-forward loop that regulates p21(waf1/cip1) expression and function in non-malignant prostate cells.	NCOR1 NCOR2	1.71e-05	5	46	2	21088000
Pubmed	Mouse germline restriction of Oct4 expression by germ cell nuclear factor.	NCOR1 NCOR2	1.71e-05	5	46	2	11702949
Pubmed	Coactivator and corepressor gene expression in rat cerebellum during postnatal development and the effect of altered thyroid status.	NCOR1 NCOR2	1.71e-05	5	46	2	10803578
Pubmed	Epigenetic regulation of MicroRNA-122 by peroxisome proliferator activated receptor-gamma and hepatitis b virus X protein in hepatocellular carcinoma cells.	NCOR1 NCOR2	1.71e-05	5	46	2	23703729
Pubmed	Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300.	NCOR1 NCOR2	1.71e-05	5	46	2	14985122
Pubmed	Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells.	NCOR1 NCOR2	1.71e-05	5	46	2	15531890
Pubmed	Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.	SMARCA2 RAPGEF1 NCOR1 NCOR2 NFKB2	1.99e-05	250	46	5	18660489
Pubmed	Nuclear receptor corepressors Ncor1 and Ncor2 (Smrt) are required for retinoic acid-dependent repression of Fgf8 during somitogenesis.	NCOR1 NCOR2	2.56e-05	6	46	2	27506116
Pubmed	The interaction of the vitamin D receptor with nuclear receptor corepressors and coactivators.	NCOR1 NCOR2	2.56e-05	6	46	2	9878542
Pubmed	Hdac3 Interaction with p300 Histone Acetyltransferase Regulates the Oligodendrocyte and Astrocyte Lineage Fate Switch.	NCOR1 NCOR2	2.56e-05	6	46	2	26859354
Pubmed	Cloning and characterization of a corepressor and potential component of the nuclear hormone receptor repression complex.	NCOR1 NCOR2	2.56e-05	6	46	2	9405624
Pubmed	AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor.	NCOR1 NCOR2	2.56e-05	6	46	2	12460926
Pubmed	SUMOylation of human peroxisome proliferator-activated receptor alpha inhibits its trans-activity through the recruitment of the nuclear corepressor NCoR.	NCOR1 NCOR2	2.56e-05	6	46	2	19955185
Pubmed	Sumoylation of peroxisome proliferator-activated receptor gamma by apoptotic cells prevents lipopolysaccharide-induced NCoR removal from kappaB binding sites mediating transrepression of proinflammatory cytokines.	NCOR1 NCOR2	2.56e-05	6	46	2	18832723
Pubmed	MicroRNA cluster 221-222 and estrogen receptor alpha interactions in breast cancer.	NCOR1 NCOR2	2.56e-05	6	46	2	20388878
Pubmed	Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway.	NCOR1 NCOR2	2.56e-05	6	46	2	10640275
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	SMARCA2 DLG1 NCOR1 MCM3 NCOR2 ZNF326 GNAS YTHDC1 ARGLU1	3.17e-05	1247	46	9	27684187
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	DLG1 NCOR1 MCM3 NCOR2 ARGLU1 SRGAP3 SPTBN2 SMG6	3.44e-05	963	46	8	28671696
Interaction	SP7 interactions	SMARCA2 LENG8 PRR12 NCOR1 NCOR2 RNF123 SCAF8	5.36e-06	304	46	7	int:SP7
Interaction	TBR1 interactions	SMARCA2 PRR12 NCOR1 NCOR2 RNF123	5.79e-06	113	46	5	int:TBR1
Interaction	SNRNP40 interactions	MAK16 LENG8 CASP8AP2 NCOR1 NCOR2 ZNF326 SNRPA YTHDC1 SCAF8	1.15e-05	637	46	9	int:SNRNP40
Interaction	NANOG interactions	SMARCA2 NCOR1 MCM3 NCOR2 ZNF326 PSIP1 ARGLU1 NFKB2	1.17e-05	481	46	8	int:NANOG
Interaction	GCM1 interactions	SMARCA2 PRR12 NCOR1 NCOR2	1.74e-05	68	46	4	int:GCM1
Interaction	MECP2 interactions	SMARCA2 LENG8 NCOR1 MCM3 MPHOSPH8 ZNF326 PSIP1 FAM32A SNRPA YTHDC1 ARGLU1 SPTBN2	2.23e-05	1287	46	12	int:MECP2
Interaction	TBCK interactions	GNAS RPL7L1 SNRPA SPTBN2	3.65e-05	82	46	4	int:TBCK
Interaction	SRSF1 interactions	MAK16 ZNF326 RPL7L1 PSIP1 SNRPA YTHDC1 ARGLU1 SMG6	3.94e-05	570	46	8	int:SRSF1
Interaction	MYCN interactions	SMARCA2 MAK16 LENG8 MCM3 ZNF326 RPL7L1 PSIP1 FAM32A SNRPA YTHDC1 ARGLU1 SMG6	4.22e-05	1373	46	12	int:MYCN
Interaction	EGR2 interactions	SMARCA2 PRR12 NCOR1 NCOR2 RPL7L1	4.29e-05	171	46	5	int:EGR2
Interaction	NUP35 interactions	SMARCA2 LENG8 PRR12 NCOR1 NCOR2 ZNF326 SCAF8	4.58e-05	424	46	7	int:NUP35
Interaction	NIFK interactions	MAK16 LENG8 RPL7L1 TTC1 FAM32A YTHDC1 ARGLU1	5.08e-05	431	46	7	int:NIFK
Interaction	ALG13 interactions	LENG8 PRR12 NCOR1 NCOR2 SCAF8	5.92e-05	183	46	5	int:ALG13
Interaction	SAP18 interactions	SMARCA2 PSIP1 SNRPA YTHDC1 ARGLU1 SMG6	6.44e-05	305	46	6	int:SAP18
Interaction	SOX17 interactions	SMARCA2 PRR12 NCOR1 NCOR2	6.50e-05	95	46	4	int:SOX17
Interaction	NFIA interactions	SMARCA2 PRR12 NCOR1 NCOR2 ZNF326	6.73e-05	188	46	5	int:NFIA
Interaction	NUP43 interactions	MAK16 CASP8AP2 NCOR1 NCOR2 PSIP1 FAM32A YTHDC1 ARGLU1	7.54e-05	625	46	8	int:NUP43
Interaction	KLF5 interactions	SMARCA2 LENG8 PRR12 NCOR1 NCOR2	8.00e-05	195	46	5	int:KLF5
Interaction	SMG7 interactions	LENG8 PRR12 NCOR1 NCOR2 SCAF8 SMG6	8.25e-05	319	46	6	int:SMG7
Interaction	RUNX1 interactions	NCOR1 NCOR2 ZNF326 PSIP1 YTHDC1 ARGLU1	8.98e-05	324	46	6	int:RUNX1
Interaction	PAX8 interactions	SMARCA2 PRR12 NCOR1 NCOR2	1.19e-04	111	46	4	int:PAX8
Interaction	TBXT interactions	SMARCA2 PRR12 NCOR1 NCOR2	1.41e-04	116	46	4	int:TBXT
Interaction	PAX6 interactions	SMARCA2 PRR12 DLG1 NCOR1 NCOR2 GPANK1	1.75e-04	366	46	6	int:PAX6
Interaction	PAX7 interactions	SMARCA2 PRR12 NCOR1 NCOR2	1.82e-04	124	46	4	int:PAX7
Interaction	PAX9 interactions	SMARCA2 PRR12 NCOR1 NCOR2	2.19e-04	130	46	4	int:PAX9
Interaction	ASF1A interactions	LENG8 CASP8AP2 NCOR1 NCOR2 SPTBN2	2.51e-04	249	46	5	int:ASF1A
Interaction	NFIB interactions	SMARCA2 PRR12 NCOR1 NCOR2	3.06e-04	142	46	4	int:NFIB
Interaction	CIT interactions	SMARCA2 MAK16 MCM3 MPHOSPH8 ZNF326 GNAS RPL7L1 PSIP1 SNRPA ARGLU1 SPTBN2	3.29e-04	1450	46	11	int:CIT
Interaction	SAMD9L interactions	RNF123 YTHDC1	3.32e-04	12	46	2	int:SAMD9L
Interaction	TNIP1 interactions	LENG8 MCM3 ZNF326 GNAS RPL7L1 PSIP1 SNRPA YTHDC1 ARGLU1 SPTBN2	3.44e-04	1217	46	10	int:TNIP1
Interaction	SMC5 interactions	LENG8 NCOR1 MCM3 NCOR2 MPHOSPH8 ZNF326 PSIP1 SNRPA ARGLU1	3.69e-04	1000	46	9	int:SMC5
Interaction	TOP3B interactions	LPIN3 PRR12 RAPGEF1 NCOR1 NCOR2 GNAS PSIP1 SNRPA NFKB2 SPTBN2 SMG6	3.70e-04	1470	46	11	int:TOP3B
Cytoband	9p22.3	SMARCA2 PSIP1	7.61e-05	13	46	2	9p22.3
Cytoband	3p25.3	TATDN2 SRGAP3	9.46e-04	45	46	2	3p25.3
GeneFamily	Ankyrin repeat domain containing	ANKRD30B MPHOSPH8 GPANK1 NFKB2	4.31e-04	242	27	4	403
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	NCOR1 NCOR2	2.82e-03	53	27	2	532
GeneFamily	RNA binding motif containing	MAK16 SNRPA SCAF8	3.83e-03	213	27	3	725
Coexpression	PYEON_HPV_POSITIVE_TUMORS_UP	SMARCA2 CASP8AP2 MCM3 PSIP1 TAF7L	9.30e-07	101	46	5	M7738
Coexpression	GRYDER_PAX3FOXO1_ENHANCERS_IN_TADS	SMARCA2 FAM217B RAPGEF1 MCM3 NCOR2 GNAS PSIP1 ARGLU1 AOPEP PCSK6	7.89e-06	1009	46	10	M157
Coexpression	GSE24671_CTRL_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_DN	SMARCA2 NCOR1 FAM32A ARGLU1 TK2	2.55e-05	199	46	5	M9443
Coexpression	STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP	SMARCA2 LENG8 CNNM1 ARGLU1 AOPEP	3.01e-05	206	46	5	M2817
Coexpression	STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP	SMARCA2 LENG8 CNNM1 ARGLU1 AOPEP	3.16e-05	208	46	5	MM581
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	SMARCA2 RAPGEF1 NCOR1 FAM53B MPHOSPH8 UBXN4 GNAS PSIP1 YTHDC1 SCAF8 SRGAP3	4.12e-05	1492	46	11	M40023
Coexpression	GRYDER_PAX3FOXO1_ENHANCERS_KO_DOWN	SMARCA2 FAM217B RAPGEF1 PSIP1 AOPEP PCSK6	1.12e-04	438	46	6	M227
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	MPHOSPH8 PSIP1 SNRPA YTHDC1 SMG6	1.81e-06	197	46	5	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
Computational	Neighborhood of BUB3	MCM3 PSIP1 SNRPA	6.78e-05	28	31	3	GNF2_BUB3
Disease	developmental disorder of mental health (implicated_via_orthology)	DLG1 NCOR1 NCOR2	5.07e-05	49	43	3	DOID:0060037 (implicated_via_orthology)
Disease	opportunistic bacterial infectious disease (implicated_via_orthology)	SMARCA2 NFKB2	7.42e-05	9	43	2	DOID:0050340 (implicated_via_orthology)
Disease	S-warfarin measurement	SMARCA2 MAK16 NCOR2	3.86e-04	97	43	3	EFO_0803323
Disease	opioid dependence	SMARCA2 RAPGEF1 ZNF326 SPTBN2	3.92e-04	237	43	4	EFO_0005611
Disease	gluteofemoral adipose tissue measurement	DLG1 NCOR2 DNAH10	9.47e-04	132	43	3	EFO_0803317
Disease	cysteine-rich with EGF-like domain protein 1 measurement	TATDN2 SRGAP3	1.00e-03	32	43	2	EFO_0021870
Disease	colorectal cancer, endometrial neoplasm	SCAF8 AOPEP	1.72e-03	42	43	2	EFO_0004230, MONDO_0005575
Disease	childhood gender nonconformity	SMARCA2 SPTBN2	1.80e-03	43	43	2	EFO_0020103
Disease	cardioembolic stroke	NCOR2 AOPEP PCSK6	1.96e-03	170	43	3	EFO_1001976

Protein segments in the cluster

Peptide	Gene	Start	Entry
RRQDRTKERPRLKKQ	SMG6	281	Q86US8
EKRRNVDILKEKIRP	ANKRD30B	1021	Q9BXX2
SRDKERVRKRSKSRE	ARGLU1	31	Q9NWB6
IPSKRRVEKKERARL	DLG1	641	Q12959
PRKRKRREKEEVFEK	AOPEP	691	Q8N6M6
PLKAERHRTEDKRKR	CASP8AP2	461	Q9UKL3
QKEVERRKERRLPQD	MMP24	571	Q9Y5R2
KKVERIENNPRRRAK	NCOR2	311	Q9Y618
RRRKPKQKEDAVATD	LPIN3	146	Q9BQK8
PLSKKVERREKRREE	MAK16	136	Q9BXY0
RKEERPKKERPRKEE	JSRP1	251	Q96MG2
QTEPARERKRKKRRI	GPANK1	61	O95872
EDPERELKKQKRAAR	LENG8	501	Q96PV6
KKVGVKRRRPEEVQE	FAM53B	276	Q14153
QEVKRRVKRQVRSDP	PCSK6	141	P29122
EKLKESISPEARRKR	FAM217B	46	Q9NTX9
EEEKIRRQVEKRREK	GOLGA6L7	516	A0A1B0GV03
QRLKKRCREEEKVIP	TK2	191	O00142
EQKRKRRKTRQPDAK	MCM3	686	P25205
KNEEEKRRGLDKRTP	FAM32A	46	Q9Y421
AEEEKPKRRRQEKQA	DDX11L8	301	A8MPP1
ESKEPKEEKQRRRCK	GNAS	206	O95467
FREIKPKREKVARLE	DNAH10	3251	Q8IVF4
RAREREKERQKKGLP	SCAF8	451	Q9UPN6
RDLKTKTREDPKENR	MPHOSPH8	236	Q99549
DPNIVRKKERGREEK	TAF7L	201	Q5H9L4
EPNKVQKRKRDRLRD	TATDN2	166	Q93075
RKRRRNVDKDPAKED	SMARCA2	1346	P51531
QKRDKVRLRRLEVKP	RPL7L1	71	Q6DKI1
KVDRIENNPRRKAKE	NCOR1	321	O75376
EKEKEKVTRGERPLR	PRR12	1741	Q9ULL5
RKKQRVPQRERKRHD	CNNM1	576	Q9NRU3
RRGRKRKAEKQVETE	PSIP1	146	O75475
KRKREEEERRKQPPA	SPTBN2	2086	O15020
EDRPQRRSSVKKIEK	SRGAP3	206	O43295
IKPRNITRRKTDREE	RAPGEF1	1061	Q13905
TEDKLRRCPKRRKDI	RNF123	786	Q5XPI4
EKTCVRKRDPERRAK	YTHDC1	131	Q96MU7
REKEIPRREEKSKRQ	TMC2	116	Q8TDI7
RLPKQIEERNERLKE	TTC1	231	Q99614
EKREPVRKRVLEKRG	UBXN4	461	Q92575
EEPEKRRRQEREKKY	TCHH	976	Q07283
FVERDRKREKRKPKS	SNRPA	101	P09012
PKNEEEEKRRIEARR	ZNF326	276	Q5BKZ1
KSIQEEKRRPRKDSQ	MYO3A	1516	Q8NEV4
DKEEVQRKRRKALPT	NFKB2	331	Q00653