Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium ion binding	CELSR3 MEGF8 PLCH2 PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	1.30e-06	749	58	12	GO:0005509
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	CELSR3 TRO PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	3.98e-12	187	58	11	GO:0007156
GeneOntologyBiologicalProcess	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB4 PCDHB3 PCDHB16	1.33e-10	53	58	7	GO:0016339
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	CELSR3 TRO PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	9.96e-10	313	58	11	GO:0098742
GeneOntologyBiologicalProcess	cell-cell adhesion	JAK2 CYP1B1 CELSR3 TRO PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 IRAK1 PCDHB16	1.21e-06	1077	58	14	GO:0098609
GeneOntologyBiologicalProcess	synapse assembly	PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB4 PCDHB3 CHRNB2 PCDHB16	2.26e-06	308	58	8	GO:0007416
GeneOntologyBiologicalProcess	cell junction assembly	PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB4 PCDHB3 CHRNB2 PCDHB16	1.82e-04	569	58	8	GO:0034329
GeneOntologyBiologicalProcess	anterograde trans-synaptic signaling	JAK2 SYNGR3 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB4 PCDHB3 CHRNB2 PCDHB16	2.43e-04	931	58	10	GO:0098916
GeneOntologyBiologicalProcess	chemical synaptic transmission	JAK2 SYNGR3 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB4 PCDHB3 CHRNB2 PCDHB16	2.43e-04	931	58	10	GO:0007268
GeneOntologyBiologicalProcess	trans-synaptic signaling	JAK2 SYNGR3 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB4 PCDHB3 CHRNB2 PCDHB16	2.60e-04	939	58	10	GO:0099537
MousePheno	abnormal maxillary nerve morphology	MEGF8 CYP26A1	9.68e-06	2	44	2	MP:0009799
MousePheno	abnormal ophthalmic nerve morphology	MEGF8 CYP26A1	5.79e-05	4	44	2	MP:0009798
Domain	Cadherin_C	PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	4.89e-15	42	57	9	IPR032455
Domain	Cadherin_C_2	PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	4.89e-15	42	57	9	PF16492
Domain	Cadherin_2	PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	3.32e-13	65	57	9	PF08266
Domain	Cadherin_N	PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	3.32e-13	65	57	9	IPR013164
Domain	Cadherin_CS	CELSR3 PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	1.03e-12	109	57	10	IPR020894
Domain	CADHERIN_1	CELSR3 PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	1.49e-12	113	57	10	PS00232
Domain	Cadherin	CELSR3 PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	1.49e-12	113	57	10	PF00028
Domain	CADHERIN_2	CELSR3 PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	1.63e-12	114	57	10	PS50268
Domain	-	CELSR3 PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	1.63e-12	114	57	10	2.60.40.60
Domain	CA	CELSR3 PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	1.78e-12	115	57	10	SM00112
Domain	Cadherin-like	CELSR3 PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	1.95e-12	116	57	10	IPR015919
Domain	Cadherin	CELSR3 PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	2.31e-12	118	57	10	IPR002126
Domain	K_chnl_volt-dep_Kv	KCNA7 KCNC2	3.06e-03	27	57	2	IPR003968
Domain	EGF_LAM_2	CELSR3 MEGF8	3.77e-03	30	57	2	PS50027
Domain	EGF_LAM_1	CELSR3 MEGF8	3.77e-03	30	57	2	PS01248
Domain	VG_K_chnl	KCNA7 KCNC2	4.55e-03	33	57	2	IPR028325
Domain	Laminin_EGF	CELSR3 MEGF8	5.10e-03	35	57	2	PF00053
Domain	EGF_Lam	CELSR3 MEGF8	5.10e-03	35	57	2	SM00180
Domain	Laminin_EGF	CELSR3 MEGF8	6.00e-03	38	57	2	IPR002049
Domain	TF_fork_head_CS_2	FOXN1 FOXL1	8.69e-03	46	57	2	IPR030456
Domain	TF_fork_head_CS_1	FOXN1 FOXL1	9.06e-03	47	57	2	IPR018122
Domain	FH	FOXN1 FOXL1	9.82e-03	49	57	2	SM00339
Domain	FORK_HEAD_1	FOXN1 FOXL1	9.82e-03	49	57	2	PS00657
Domain	FORK_HEAD_2	FOXN1 FOXL1	9.82e-03	49	57	2	PS00658
Domain	Fork_head_dom	FOXN1 FOXL1	9.82e-03	49	57	2	IPR001766
Domain	FORK_HEAD_3	FOXN1 FOXL1	9.82e-03	49	57	2	PS50039
Domain	Forkhead	FOXN1 FOXL1	9.82e-03	49	57	2	PF00250
Pathway	KEGG_MEDICUS_ENV_FACTOR_NICOTINE_TO_JAK_STAT_SIGNALING_PATHWAY	JAK2 CHRNB2	7.04e-05	5	38	2	M48978
Pubmed	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.	PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	1.02e-20	20	59	9	11322959
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	CELSR3 PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	4.37e-17	72	59	10	10380929
Pubmed	Protocadherins.	PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB4 PCDHB3 PCDHB16	4.76e-17	13	59	7	12231349
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	CELSR3 PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	1.33e-16	80	59	10	10716726
Pubmed	Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.	PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	5.18e-16	57	59	9	32633719
Pubmed	CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.	PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	6.13e-16	58	59	9	30377227
Pubmed	Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.	PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	2.80e-15	68	59	9	11230163
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	6.23e-15	74	59	9	10817752
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	9.06e-15	77	59	9	10835267
Pubmed	Single-neuron diversity generated by Protocadherin-β cluster in mouse central and peripheral nervous systems.	PCDHB15 PCDHB11 PCDHB7 PCDHB3	1.56e-09	10	59	4	22969705
Pubmed	Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system.	PCDHB15 PCDHB11 PCDHB4 PCDHB3	1.75e-08	17	59	4	18279309
Pubmed	Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes.	PCDHB15 PCDHB11 PCDHB4 PCDHB3 PCDHB16	5.51e-08	59	59	5	23754746
Pubmed	Identification of novel cadherins expressed in human melanoma cells.	PCDHB14 PCDHB11 PCDHB16	1.62e-07	7	59	3	9182820
Pubmed	A unique role of cohesin-SA1 in gene regulation and development.	PCDHB15 PCDHB14 PCDHB16	2.56e-06	16	59	3	22415368
Pubmed	Structural basis for phosphotyrosine recognition by the Src homology-2 domains of the adapter proteins SH2-B and APS.	JAK2 SH2B1	2.83e-06	2	59	2	16824542
Pubmed	Identification of SH2-Bbeta as a substrate of the tyrosine kinase JAK2 involved in growth hormone signaling.	JAK2 SH2B1	2.83e-06	2	59	2	9343427
Pubmed	Tyrosine 813 is a site of JAK2 autophosphorylation critical for activation of JAK2 by SH2-B beta.	JAK2 SH2B1	8.48e-06	3	59	2	15121872
Pubmed	The Dyslexia-susceptibility Protein KIAA0319 Inhibits Axon Growth Through Smad2 Signaling.	JAK2 SH2B1	8.48e-06	3	59	2	28334068
Pubmed	Jak2 is involved in c-Myc induction by Bcr-Abl.	JAK2 SH2B1	8.48e-06	3	59	2	12370803
Pubmed	[Molecular mechanism of SH2B1 in regulating JAK2/IRS2 during obesity development].	JAK2 SH2B1	8.48e-06	3	59	2	20360640
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	JAK2 CCDC71L EHBP1L1 CELSR3 MEGF8 HELZ2 IRAK1 GBA2 KIFC2 FAM83H	1.54e-05	1105	59	10	35748872
Pubmed	SH2B1 enhances leptin signaling by both Janus kinase 2 Tyr813 phosphorylation-dependent and -independent mechanisms.	JAK2 SH2B1	1.69e-05	4	59	2	17565041
Pubmed	α4β2 nicotinic receptors partially mediate anti-inflammatory effects through Janus kinase 2-signal transducer and activator of transcription 3 but not calcium or cAMP signaling.	JAK2 CHRNB2	1.69e-05	4	59	2	20943775
Pubmed	Lnk inhibits myeloproliferative disorder-associated JAK2 mutant, JAK2V617F.	JAK2 SH2B1	1.69e-05	4	59	2	19293402
Pubmed	SH2-B promotes insulin receptor substrate 1 (IRS1)- and IRS2-mediated activation of the phosphatidylinositol 3-kinase pathway in response to leptin.	JAK2 SH2B1	2.82e-05	5	59	2	15316008
Pubmed	Mammary gland remodeling depends on gp130 signaling through Stat3 and MAPK.	JAK2 FOXN1	2.82e-05	5	59	2	15292206
Pubmed	Kinase activation through dimerization by human SH2-B.	JAK2 SH2B1	2.82e-05	5	59	2	15767667
Pubmed	WT1-mediated gene regulation in early urogenital ridge development.	CYP1B1 GATA6 ZIC1	6.25e-05	45	59	3	18391535
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	JAK2 CYP1B1 ABHD5 GPAA1 TRO SYNGR3 IRAK1 NCAPG2 STT3A	7.06e-05	1061	59	9	33845483
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FOXN1 TRO DDX52 SYNGR3 FBXW5 LARP1 SH2B1 FOXL1	9.61e-05	857	59	8	25609649
Pubmed	Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.	CELSR3 MEGF8	1.01e-04	9	59	2	9693030
Pubmed	Molecular cloning of murine STAP-1, the stem-cell-specific adaptor protein containing PH and SH2 domains.	JAK2 SH2B1	2.93e-04	15	59	2	10679268
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	EHBP1L1 EIF4H SLC16A3 IRAK1 LARP1 FAM83H	3.89e-04	565	59	6	25468996
Pubmed	REST corepressors RCOR1 and RCOR2 and the repressor INSM1 regulate the proliferation-differentiation balance in the developing brain.	CELSR3 CHRNB2	4.25e-04	18	59	2	28049845
Pubmed	Distinct and Cooperative Functions for the Protocadherin-α, -β and -γ Clusters in Neuronal Survival and Axon Targeting.	PCDHB15 PCDHB4	4.75e-04	19	59	2	28066179
Pubmed	Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome.	PCDHB14 PCDHB16	4.75e-04	19	59	2	23920377
Pubmed	Embryonic retinoic acid synthesis is essential for heart morphogenesis in the mouse.	CYP26A1 GATA6	5.27e-04	20	59	2	11245568
Pubmed	Retinoic acid, hypoxia, and GATA factors cooperatively control the onset of fetal liver erythropoietin expression and erythropoietic differentiation.	CYP26A1 GATA6	7.00e-04	23	59	2	15766748
Pubmed	Identification of potential target genes for RFX4_v3, a transcription factor critical for brain development.	CYP26A1 ZIC1	7.00e-04	23	59	2	16893423
Pubmed	Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.	PCDHB15 PCDHB3	7.62e-04	24	59	2	24698270
Pubmed	Defining the membrane proteome of NK cells.	EHBP1L1 GPAA1 EIF4H DDX52 HELZ2 LARP1 NCAPG2 STT3A	7.67e-04	1168	59	8	19946888
Pubmed	Gamma protocadherins are required for survival of spinal interneurons.	PCDHB15 PCDHB16	8.96e-04	26	59	2	12467588
Pubmed	Rhombomere-specific analysis reveals the repertoire of genetic cues expressed across the developing hindbrain.	CYP1B1 CELSR3	9.66e-04	27	59	2	19208226
Pubmed	Abnormal neocortex arealization and Sotos-like syndrome-associated behavior in Setd2 mutant mice.	PCDHB3 PCDHB16	1.04e-03	28	59	2	33523829
Pubmed	Voltage-gated potassium channel genes are clustered in paralogous regions of the mouse genome.	KCNA7 KCNC2	1.27e-03	31	59	2	8034307
Pubmed	The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse.	GATA6 FOXL1	1.36e-03	32	59	2	23369715
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HELZ2 ZNF629 ARMCX2 GBA2 SH2B1	1.50e-03	493	59	5	15368895
Pubmed	High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.	RNF220 EHBP1L1 MEGF8 EIF4H SLC16A3 LARP1 NCAPG2	1.66e-03	1021	59	7	26760575
Interaction	PCDHB10 interactions	PCDHB10 PCDHB3 PCDHB16	7.45e-07	7	57	3	int:PCDHB10
Interaction	PCDHB3 interactions	PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	2.85e-06	141	57	6	int:PCDHB3
Interaction	PCDHB16 interactions	PCDHB10 PCDHB7 PCDHB3 PCDHB16	5.39e-06	41	57	4	int:PCDHB16
Interaction	TMTC2 interactions	PCDHB11 PCDHB7 PCDHB3	9.53e-06	15	57	3	int:TMTC2
Interaction	PCDHB9 interactions	PCDHB9 PCDHB3	2.35e-05	3	57	2	int:PCDHB9
Interaction	PCDHB4 interactions	PCDHB4 PCDHB3	2.35e-05	3	57	2	int:PCDHB4
Interaction	PCDHB13 interactions	PCDHB11 PCDHB3	7.82e-05	5	57	2	int:PCDHB13
Cytoband	5q31	PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	3.19e-14	115	59	9	5q31
Cytoband	Ensembl 112 genes in cytogenetic band chr5q31	PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	1.71e-10	298	59	9	chr5q31
Cytoband	8q24.3	GPAA1 KIFC2 OPLAH FAM83H	1.43e-05	113	59	4	8q24.3
Cytoband	Ensembl 112 genes in cytogenetic band chr8q24	GPAA1 KIFC2 OPLAH FAM83H	1.14e-03	355	59	4	chr8q24
GeneFamily	Clustered protocadherins	PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB7 PCDHB4 PCDHB3 PCDHB16	3.12e-14	64	44	9	20
GeneFamily	Potassium voltage-gated channels	KCNA7 KCNC2	4.26e-03	40	44	2	274
GeneFamily	Forkhead boxes	FOXN1 FOXL1	4.91e-03	43	44	2	508
Coexpression	MIKKELSEN_ES_HCP_WITH_H3K27ME3	PCDHB15 PCDHB14 PCDHB11 PCDHB7 PCDHB16	3.88e-08	42	59	5	MM1275
Coexpression	MIKKELSEN_IPS_HCP_WITH_H3_UNMETHYLATED	PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 KIAA1755	6.56e-08	93	59	6	MM1266
Coexpression	MIKKELSEN_ES_HCP_WITH_H3K27ME3	PCDHB15 PCDHB14 PCDHB7 PCDHB16	2.20e-06	41	59	4	M2000
Coexpression	HAY_BONE_MARROW_STROMAL	TRHDE CYP1B1 PCDHB15 PCDHB14 PCDHB10 PCDHB7 KIAA1755 ARMCX2 PCDHB16 ZIC1	7.46e-06	767	59	10	M39209
Coexpression	FIGUEROA_AML_METHYLATION_CLUSTER_3_UP	PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB16	4.08e-05	170	59	5	M2168
Coexpression	MIKKELSEN_IPS_HCP_WITH_H3_UNMETHYLATED	PCDHB15 PCDHB14 PCDHB10 KIAA1755	4.28e-05	86	59	4	M1968
Coexpression	KRAS.DF.V1_UP	JAK2 EHBP1L1 PLCH2 GATA6 OPLAH	7.09e-05	191	59	5	M2863
CoexpressionAtlas	PP_RBC_top-relative-expression-ranked_2500_k-means-cluster#3	PCDHB15 PCDHB14 PCDHB11 PCDHB10 PCDHB9 PCDHB3	4.54e-06	158	58	6	PP_RBC_2500_K3
ToppCell	facs-Lung-EPCAM-18m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPAA1 KCNC2 PCDHB15 PCDHB14 PCDHB10 PCDHB7	1.02e-07	170	59	6	12203d4410f38cc933d9f160b5fb76828df94119
ToppCell	facs-Lung-EPCAM-18m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPAA1 KCNC2 PCDHB15 PCDHB14 PCDHB10 PCDHB7	1.02e-07	170	59	6	f9decb3bf3bf6d4996b0ac27af768236e116aac5
ToppCell	10x5'v1-week_12-13-Endothelial-stroma-sinusoidal_EC\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PCDHB15 PCDHB9 PCDHB7 ALPK3 GATA6	4.78e-06	186	59	5	e8ead5634686ebaa6a230eea69795d923ce9939d
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP1B1 TRO PCDHB11 GATA6 KIAA1755	4.91e-06	187	59	5	ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GPAA1 TRO PCDHB14 HELZ2	5.46e-05	156	59	4	895927228c93cd090303984c5be6ebfb59ed6f3a
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCDHB14 ZNF629 PCDHB3 EME2	5.59e-05	157	59	4	1f21d78a467fe22c5ab75d0917b840c1ac93f32c
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC16A3 SYNGR3 EME2 ZIC1	8.33e-05	174	59	4	4a18b51501eaaeb7907e99316ba8ae15b2c7d529
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-Granular_Neuron_CB_Gabra6\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	QRFP KCNC2 TRO PCDHB4	8.90e-05	177	59	4	9b02fd91c110b405eba6cb74ceb90b1286535973
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF33 PCDHB14 STOX1 ARMCX2	1.06e-04	185	59	4	742350093d90f96735dc73e3360cdd749bae63fd
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE ARHGEF33 PLCH2 ZIC1	1.08e-04	186	59	4	a1ab273b01971d6a892912560d387685dd657179
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CELSR3 SYNGR3 KIFC2 CHRNB2	1.08e-04	186	59	4	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRHDE TRO PLCH2 ZIC1	1.10e-04	187	59	4	1b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PCDHB15 PCDHB10 PCDHB4 PCDHB16	1.15e-04	189	59	4	8e6b6025f5554672e26a5d19fe365acb4333789c
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 GATA6 KIAA1755 FOXL1	1.15e-04	189	59	4	378f26f751ab4b470948c35dd8347de72dd12ff7
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 GATA6 KIAA1755 FOXL1	1.15e-04	189	59	4	f0a2d4ef9896d764971ebbc6952510c128bb76e8
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHB14 PCDHB9 PCDHB7 OPLAH	1.15e-04	189	59	4	1db5dd1ef2a65251af2d5696622d1dd9c4ae2b55
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHB14 PCDHB9 PCDHB7 OPLAH	1.15e-04	189	59	4	bfb1c183a8a2752a2368b74150e66181c6a9da48
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHB14 PCDHB9 PCDHB7 OPLAH	1.15e-04	189	59	4	14833feea8f80744a06ece73f813eaeff8c4dd61
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CELSR3 SYNGR3 KIFC2 CHRNB2	1.17e-04	190	59	4	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYP1B1 GATA6 KIAA1755 FOXL1	1.22e-04	192	59	4	f9fb24457999dc9e751a099d7f995543b9330ad4
ToppCell	facs-Kidney-nan-18m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 GATA6 NCAPG2 PCDHB16	1.27e-04	194	59	4	bbc625b4cc53bb7d6254fde287258e51f9171572
ToppCell	facs-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 GATA6 NCAPG2 PCDHB16	1.27e-04	194	59	4	fcd5e9238d299c41f0bf9693b56cd8c900d2112b
ToppCell	facs-Kidney-nan-18m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1B1 GATA6 NCAPG2 PCDHB16	1.27e-04	194	59	4	6afc21c5fec30ab8e373e3e46ab7866204c805b6
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW12-Neuronal-GABAergic_neurons\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	ARHGEF33 KCNA7 HELZ2 PCDHB3	1.29e-04	195	59	4	efdea22118d5be46c5abfe8e3fbe39503390665d
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNC2 TRO SYNGR3 CHRNB2	1.29e-04	195	59	4	ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCell	facs-Heart-RA-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC71L CYP1B1 KCNC2 STT3A	1.34e-04	197	59	4	940cf1e54d7c820e04946258a8b784f35c6a144c
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Mgp_(Gkn3)--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	QRFP ALPK3 GATA6	1.76e-04	82	59	3	72d5a55ca7c03e9c54f865524e206b288f242017
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Mgp_(Gkn3)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	QRFP ALPK3 GATA6	1.76e-04	82	59	3	e500582511814a067852dc3bd78d19937c28ba60
ToppCell	Globus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Mgp_(Gkn3)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	QRFP ALPK3 GATA6	1.76e-04	82	59	3	ea3bdd7b871269eacb81167c6cf59a0e21bf6d83
Disease	5-oxoproline measurement	GPAA1 OPLAH	3.74e-04	16	53	2	EFO_0010988
Disease	ankylosing spondylitis (is_implicated_in)	JAK2 IRAK1	5.31e-04	19	53	2	DOID:7147 (is_implicated_in)
Disease	colon adenocarcinoma (is_marker_for)	JAK2 ABHD5	9.25e-04	25	53	2	DOID:234 (is_marker_for)
Disease	colon adenocarcinoma (is_implicated_in)	JAK2 ABHD5	1.00e-03	26	53	2	DOID:234 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
EDRAFGAVPVAGFFL	TRHDE	196	Q9UKU6
SEPRARAFCEAGADG	nan	51	Q8N814
GAGAKFDTRRFSADA	DDX52	11	Q9Y2R4
IFAAEARAAPGFGEV	ALPK3	1686	Q96L96
AAAVAARGASRTFFP	ARHGEF33	751	A8MVX0
SPRAGARELGEFHAF	CAPN10	226	Q9HC96
FRPGDGAAAAAAASA	ARMCX2	311	Q7L311
ARAAGVFGDRLAGVF	RNF32-DT	46	Q8NI28
RIGALGFSGAFEDRD	JAK2	826	O60674
AGAAGAGRRDFVEAP	LARP1	106	Q6PKG0
RDDFNSGFRDDFLGG	EIF4H	151	Q15056
RASDHPGGGREFFFD	KCNC2	91	Q96PR1
GGDRARAFARDFAAH	GPAA1	66	O43292
GFIDIFARPAAGFVA	SLC16A3	271	O15427
ATARGAGEAERAEFP	KIAA1755	911	Q5JYT7
VLGEGRGSDAFFDAL	FBXW5	381	Q969U6
ERFAELSPFAGRAAA	NANOS1	146	Q8WY41
AADRADGAAPGVASR	EHBP1L1	1196	Q8N3D4
RDPAFSARIGAAGAF	MEGF8	221	Q7Z7M0
AFEFRVGATDRGSPA	PCDHB10	526	Q9UN67
AFEFRVGATDRGFPA	PCDHB15	526	Q9Y5E8
LGDFGLARFSRFAGS	IRAK1	356	P51617
AFDFRVGATDRGSPA	PCDHB11	526	Q9Y5F2
FRFGRQDEGSEATGF	QRFP	86	P83859
FEFRVGASDRGSPAL	PCDHB4	526	Q9Y5E5
AFEFRVGATDRGSPA	PCDHB16	526	Q9NRJ7
EFEFRVGATDRGSPA	PCDHB14	526	Q9Y5E9
AFEFRVGATDRGSPA	PCDHB7	526	Q9Y5E2
PKRFGAAGADASDSR	GATA6	11	Q92908
AAGADASDSRAFPAR	GATA6	16	Q92908
PDFRDDRDGTGLAAA	KCNA7	166	Q96RP8
TRFFGQDGDAAPALS	GBA2	431	Q9HCG7
RGDAAATDDPAARFQ	DPP9	11	Q86TI2
AFAPAAALAASGRAE	FOXL1	31	Q12952
PATAARGGDFRAEDG	CCDC71L	16	Q8N9Z2
DASRFSFIPFGGGLR	CYP26A1	426	O43174
GSAFADRPAFASFRV	CYP1B1	111	Q16678
SAGSEAAARARDPAG	EME2	41	A4GXA9
RFVGPPAARAAAAAA	CELSR3	471	Q9NYQ7
PAGELAGARGFFQAR	FAM83H	386	Q6ZRV2
LRGGRAGFADPDDFT	FAM83H	476	Q6ZRV2
DVEARRQGAAFYAPG	HELZ2	1386	Q9BYK8
FRRDGGAAAAAEPGD	KIFC2	16	Q96AC6
AFEFRVGATDRGSPA	PCDHB3	526	Q9Y5E6
AFDFRVGASDRGSPA	PCDHB9	526	Q9Y5E1
AGPGAEAAFSRRFAE	SH2B1	56	Q9NRF2
TAGAGSLAPGRREFF	TDRD6	106	O60522
RSPRAGDFGAAFVER	OPLAH	601	O14841
GFGFEEAAASSPGRF	FOXN1	101	O15353
SARGGDGSRIIFDDF	STT3A	491	P46977
GVGAFRPFASTEDRE	RNF220	116	Q5VTB9
GFAGRDASRAFVTGD	CYB5D2	81	Q8WUJ1
EGAGALFFREAPGAD	CHRNB2	371	P17787
GFGRSSRPRFDSDAE	ABHD5	111	Q8WTS1
RGFSEAAAPRAFGLH	NCAPG2	811	Q86XI2
SDGFGSRPNASFDRG	TRO	1316	Q12816
TADDFAPSFEGGSRR	PLCH2	1261	O75038
GAAEEPGGRAVFRAF	STOX1	26	Q6ZVD7
ASSPDDGGRTDRFAF	PPP1R3F	231	Q6ZSY5
DGGRTDRFAFQLPFA	PPP1R3F	236	Q6ZSY5
DRFAFQLPFAEGAGD	PPP1R3F	241	Q6ZSY5
FGAGRAGAALDPVSF	SYNGR3	6	O43761
LFRNRGFGDAAAAAS	ZIC1	101	Q15915
FRGNSYPGAAEGRAE	ZNF629	621	Q9UEG4