Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontRNA-4-demethylwyosine synthase activity

TYW1B TYW1

7.52e-08262GO:0102521
GeneOntologyMolecularFunctionoxo-acid-lyase activity

TYW1B TYW1

1.58e-06762GO:0016833
GeneOntologyMolecularFunctioncatalytic activity, acting on a tRNA

TYW1B TYW1 MARS2

7.23e-0614463GO:0140101
GeneOntologyMolecularFunctionFMN binding

TYW1B TYW1

9.01e-061662GO:0010181
GeneOntologyMolecularFunctionlyase activity

FASN TYW1B TYW1

2.30e-0521263GO:0016829
GeneOntologyMolecularFunction4 iron, 4 sulfur cluster binding

TYW1B TYW1

8.09e-054762GO:0051539
GeneOntologyMolecularFunctioncarbon-carbon lyase activity

TYW1B TYW1

1.15e-045662GO:0016830
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

TYW1B TYW1 MARS2

1.73e-0441763GO:0140098
GeneOntologyMolecularFunctioniron-sulfur cluster binding

TYW1B TYW1

2.24e-047862GO:0051536
GeneOntologyMolecularFunctionmetal cluster binding

TYW1B TYW1

2.53e-048362GO:0051540
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

TYW1B TYW1 MARS2

6.24e-0464563GO:0140640
GeneOntologyBiologicalProcesswybutosine metabolic process

TYW1B TYW1

1.06e-06662GO:0031590
GeneOntologyBiologicalProcesswybutosine biosynthetic process

TYW1B TYW1

1.06e-06662GO:0031591
GeneOntologyBiologicalProcesstRNA metabolic process

TYW1B TYW1 MARS2

2.01e-0520963GO:0006399
GeneOntologyBiologicalProcessglycosyl compound biosynthetic process

TYW1B TYW1

2.28e-052662GO:1901659
GeneOntologyBiologicalProcesstRNA modification

TYW1B TYW1

3.05e-049462GO:0006400
GeneOntologyBiologicalProcessglycosyl compound metabolic process

TYW1B TYW1

3.18e-049662GO:1901657
GeneOntologyBiologicalProcesstRNA processing

TYW1B TYW1

6.55e-0413862GO:0008033
GeneOntologyBiologicalProcessRNA modification

TYW1B TYW1

1.06e-0317662GO:0009451
GeneOntologyBiologicalProcesscarbohydrate derivative metabolic process

FASN TYW1B TYW1

3.66e-03122663GO:1901135
GeneOntologyBiologicalProcessRNA processing

TYW1B TYW1 TDRD6

6.50e-03150063GO:0006396
MousePhenoimpaired pupillary reflex

TYW1B TYW1

3.35e-046762MP:0006243
MousePhenoabnormal pupillary reflex

TYW1B TYW1

4.09e-047462MP:0002638
MousePhenodecreased circulating alkaline phosphatase level

TYW1B TYW1

9.18e-0411162MP:0002966
MousePhenoincreased mean corpuscular hemoglobin concentration

TYW1B TYW1

1.09e-0312162MP:0005641
DomainWyosine_form

TYW1B TYW1

1.20e-07272PF08608
DomaintRNA_wybutosine-synth

TYW1B TYW1

1.20e-07272IPR013917
DomainFlavodoxin/NO_synth

TYW1B TYW1

3.37e-06872IPR008254
DomainFlavdoxin-like

TYW1B TYW1

3.37e-06872IPR001094
DomainFLAVODOXIN_LIKE

TYW1B TYW1

3.37e-06872PS50902
DomainFlavodoxin_1

TYW1B TYW1

3.37e-06872PF00258
DomainrSAM

TYW1B TYW1

4.33e-06972IPR007197
DomainRadical_SAM

TYW1B TYW1

4.33e-06972PF04055
DomainFlavoprotein-like_dom

TYW1B TYW1

5.41e-061072IPR029039
Domain-

TYW1B TYW1

5.41e-0610723.40.50.360
Domain-

TYW1B TYW1

1.03e-0442723.20.20.70
DomainAldolase_TIM

TYW1B TYW1

1.13e-044472IPR013785
Pubmed

Discovery of a gene family critical to wyosine base formation in a subset of phenylalanine-specific transfer RNAs.

TYW1B TYW1

4.63e-0828216162496
Pubmed

Ribonucleome analysis identified enzyme genes responsible for wybutosine synthesis.

TYW1B TYW1

2.78e-0748217150819
Pubmed

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.

NBPF15 NBPF19

9.70e-06218216079250
Pubmed

Functional consequences of necdin nucleocytoplasmic localization.

TYW1B TYW1

9.27e-05648222442722
CytobandEnsembl 112 genes in cytogenetic band chr7q11

TYW1B TYW1

9.50e-0427182chr7q11
CytobandEnsembl 112 genes in cytogenetic band chr1q21

NBPF15 NBPF19

2.09e-0340482chr1q21
GeneFamilyNeuroblastoma breakpoint family

NBPF15 NBPF19

2.31e-052362662
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Stem_cells-neuroepithelial-like_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

NBPF19 TDRD6

2.19e-04127829071cd0953c8bb6746dc9cd13d153e3d6ef40b08
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TYW1B ARHGAP17

3.34e-04157824183dbed6b31ebe13ef33eb19ba6d0fb4f625953
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

TYW1B ARHGAP17

3.38e-0415882de65af8d3b8514b17978155f31975e2347b75251
ToppCellSevere-B_naive-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

NBPF15 ARHGAP17

3.43e-04159822881b054bbeb479221ee3c38bbd9b0815b123579
ToppCellBronchial_Biopsy-Immune-Neutrophils|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

NBPF15 MARS2

3.56e-0416282985adca17b0c99563feef7910f3da5df31e636b6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FASN TDRD6

3.73e-0416682c11dcf9705b85ac3da6ae86358f5ffd64ae8327e
ToppCellmetastatic_Brain-Endothelial_cells-Stalk-like_ECs|Endothelial_cells / Location, Cell class and cell subclass

NBPF15 NBPF19

4.15e-0417582f6a6db992e803d36c866a91706b02f67e0fd3e09
ToppCellCOVID-19_Convalescent|World / Disease condition and Cell class

NBPF15 NBPF19

4.44e-0418182a62115a8da486fc61225901c72b1ec70bcaf4c36
ToppCell10x5'|World / Manually curated celltypes from each tissue

NBPF15 ARHGAP17

5.14e-0419582de28b998793271c4f69ce9e183c3e62d809e9cc8
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MARS2 TDRD6

5.36e-0419982bd43a84e84d8acb8e1008b98a235cc5bd5f43586
Drugacylate

FASN MARS2

2.28e-047672CID000020186
Drugmotexafin gadolinium

FASN ARHGAP17

8.40e-0414672ctd:C437683
DrugZinc Acetate

FASN ARHGAP17

1.08e-0316672ctd:D019345
DrugEugenol

FASN ARHGAP17

2.05e-0322972ctd:D005054
Drugdibenzo(a,l)pyrene

FASN ARHGAP17

4.09e-0332672ctd:C041517
Diseasewaist circumference

FASN TYW1B

2.05e-0342952EFO_0004342

Protein segments in the cluster

PeptideGeneStartEntry
QEALWHVPEHAVVLE

FASN

746

P49327
HIPEEVVVWFQETIL

TDRD6

1106

O60522
HVEWEDAVHIIPENE

NBPF15

246

Q8N660
HVEWEDAVHIIPENE

NBPF19

246

A0A087WUL8
HVVAVIEPIIQHADW

ARHGAP17

426

Q68EM7
EPFHHVVLQWLDEEL

MARS2

236

Q96GW9
VPWHEEVVQFVHELV

TYW1

621

Q9NV66
HVPWHEEVVQFVREL

TYW1B

556

Q6NUM6