Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	modified amino acid binding	MTERF1 ANXA6 SYT2 CPS1 SYT1 SYT5	9.97e-05	122	121	6	GO:0072341
GeneOntologyMolecularFunction	syntaxin binding	SYT2 VPS52 SYT1 SYT5 UNC13A	1.87e-04	87	121	5	GO:0019905
GeneOntologyMolecularFunction	glucokinase activity	HK2 HKDC1	3.60e-04	5	121	2	GO:0004340
GeneOntologyMolecularFunction	hexokinase activity	HK2 HKDC1	3.60e-04	5	121	2	GO:0004396
GeneOntologyMolecularFunction	fructokinase activity	HK2 HKDC1	3.60e-04	5	121	2	GO:0008865
GeneOntologyMolecularFunction	calcium-dependent phospholipid binding	ANXA6 SYT2 SYT1 SYT5	4.81e-04	60	121	4	GO:0005544
GeneOntologyMolecularFunction	clathrin binding	SYT2 CEMIP SYT1 SYT5	5.80e-04	63	121	4	GO:0030276
GeneOntologyBiologicalProcess	calcium ion-regulated exocytosis of neurotransmitter	SYT2 SYT1 SYT5 UNC13A	1.34e-05	25	122	4	GO:0048791
GeneOntologyCellularComponent	RNA cap binding complex	NCBP2 EIF4G1 EIF4G2 EIF4G3	2.48e-06	17	122	4	GO:0034518
GeneOntologyCellularComponent	eukaryotic translation initiation factor 4F complex	EIF4G1 EIF4G2 EIF4G3	5.31e-05	13	122	3	GO:0016281
GeneOntologyCellularComponent	NatA complex	NAA15 NAA16	3.34e-04	5	122	2	GO:0031415
GeneOntologyCellularComponent	Mon1-Ccz1 complex	CCZ1B CCZ1	3.34e-04	5	122	2	GO:0035658
GeneOntologyCellularComponent	neuromuscular junction	SYT2 TRIP4 PRKCE PRKCQ UNC13A	5.08e-04	112	122	5	GO:0031594
MousePheno	decreased skeletal muscle size	MYH4 CLCC1 MTOR WFIKKN1 WFIKKN2 PLA2G6	1.50e-05	81	92	6	MP:0010240
MousePheno	abnormal skeletal muscle size	MYH4 CLCC1 MTOR WFIKKN1 WFIKKN2 PLA2G6	3.32e-05	93	92	6	MP:0009458
Domain	MA3	EIF4G1 EIF4G2 EIF4G3	5.10e-06	6	120	3	SM00544
Domain	MA3	EIF4G1 EIF4G2 EIF4G3	5.10e-06	6	120	3	PF02847
Domain	Initiation_fac_eIF4g_MI	EIF4G1 EIF4G2 EIF4G3	5.10e-06	6	120	3	IPR003891
Domain	MI	EIF4G1 EIF4G2 EIF4G3	5.10e-06	6	120	3	PS51366
Domain	eIF5C	EIF4G1 EIF4G2 EIF4G3	8.88e-06	7	120	3	SM00515
Domain	W2	EIF4G1 EIF4G2 EIF4G3	8.88e-06	7	120	3	PF02020
Domain	W2	EIF4G1 EIF4G2 EIF4G3	8.88e-06	7	120	3	PS51363
Domain	W2_domain	EIF4G1 EIF4G2 EIF4G3	8.88e-06	7	120	3	IPR003307
Domain	MIF4G	EIF4G1 EIF4G2 EIF4G3	3.00e-05	10	120	3	SM00543
Domain	MIF4G	EIF4G1 EIF4G2 EIF4G3	3.00e-05	10	120	3	PF02854
Domain	MIF4G-like_typ-3	EIF4G1 EIF4G2 EIF4G3	3.00e-05	10	120	3	IPR003890
Domain	Synaptotagmin1	SYT2 SYT1	4.09e-05	2	120	2	IPR015428
Domain	NatA_aux_su	NAA15 NAA16	4.09e-05	2	120	2	IPR021183
Domain	DUF1712	CCZ1B CCZ1	4.09e-05	2	120	2	PF08217
Domain	NARP1	NAA15 NAA16	4.09e-05	2	120	2	PF12569
Domain	DUF1712_fun	CCZ1B CCZ1	4.09e-05	2	120	2	IPR013176
Domain	-	EIF4G1 EIF4G2 EIF4G3	1.11e-04	15	120	3	1.25.40.180
Domain	MIF4-like	EIF4G1 EIF4G2 EIF4G3	1.11e-04	15	120	3	IPR016021
Domain	tRNAsynth_Ia_anticodon-bd	RARS1 LARS1 GUCY1A2	1.11e-04	15	120	3	IPR009080
Domain	KAZAL_1	FSTL4 WFIKKN1 WFIKKN2	1.97e-04	18	120	3	PS00282
Domain	Prot_kin_PKC_delta	PRKCE PRKCQ	2.44e-04	4	120	2	IPR014376
Domain	Synaptotagmin	SYT2 SYT1 SYT5	2.72e-04	20	120	3	IPR001565
Domain	C2	SYT2 SYT1 PRKCE SYT5 PRKCQ UNC13A	3.12e-04	142	120	6	PS50004
Domain	-	SYT2 SYT1 PRKCE SYT5 PRKCQ UNC13A	3.89e-04	148	120	6	2.60.40.150
Domain	Hexokinase_2	HK2 HKDC1	4.04e-04	5	120	2	PF03727
Domain	Hexokinase_BS	HK2 HKDC1	4.04e-04	5	120	2	IPR019807
Domain	Hexokinase_C	HK2 HKDC1	4.04e-04	5	120	2	IPR022673
Domain	Hexokinase_N	HK2 HKDC1	4.04e-04	5	120	2	IPR022672
Domain	Hexokinase_1	HK2 HKDC1	4.04e-04	5	120	2	PF00349
Domain	HEXOKINASE_2	HK2 HKDC1	4.04e-04	5	120	2	PS51748
Domain	HEXOKINASE_1	HK2 HKDC1	4.04e-04	5	120	2	PS00378
Domain	AGC-kinase_C	GRK5 LATS1 PRKCE PRKCQ	4.60e-04	56	120	4	IPR000961
Domain	AGC_KINASE_CTER	GRK5 LATS1 PRKCE PRKCQ	4.60e-04	56	120	4	PS51285
Domain	S_TK_X	GRK5 LATS1 PRKCE PRKCQ	4.60e-04	56	120	4	SM00133
Domain	Keratin_2_head	KRT6A KRT6B KRT6C	4.74e-04	24	120	3	IPR032444
Domain	Keratin_2_head	KRT6A KRT6B KRT6C	4.74e-04	24	120	3	PF16208
Domain	Keratin_II	KRT6A KRT6B KRT6C	6.04e-04	26	120	3	IPR003054
Domain	Hexokinase	HK2 HKDC1	6.04e-04	6	120	2	IPR001312
Domain	CPSASE_2	MCCC1 CPS1	6.04e-04	6	120	2	PS00867
Domain	C2_dom	SYT2 SYT1 PRKCE SYT5 PRKCQ UNC13A	6.70e-04	164	120	6	IPR000008
Domain	TPR_REGION	RANBP2 NAA15 DNAH2 UNC45A CFAP46 NAA16	6.91e-04	165	120	6	PS50293
Domain	TPR	RANBP2 NAA15 DNAH2 UNC45A CFAP46 NAA16	6.91e-04	165	120	6	PS50005
Domain	CbamoylP_synth_lsu-like_ATP-bd	MCCC1 CPS1	8.42e-04	7	120	2	IPR005479
Domain	BC-like_N	MCCC1 CPS1	8.42e-04	7	120	2	IPR005481
Domain	CPSase_L_D2	MCCC1 CPS1	8.42e-04	7	120	2	PF02786
Domain	Biotin_carb_N	MCCC1 CPS1	8.42e-04	7	120	2	PF00289
Domain	C2	SYT2 SYT1 PRKCE SYT5 UNC13A	1.57e-03	131	120	5	PF00168
Domain	Kazal_2	FSTL4 WFIKKN1 WFIKKN2	1.58e-03	36	120	3	PF07648
Domain	Pkinase_C	LATS1 PRKCE PRKCQ	1.71e-03	37	120	3	IPR017892
Domain	C2	SYT2 SYT1 PRKCE SYT5 UNC13A	1.92e-03	137	120	5	SM00239
Domain	STAS	SLC26A2 SLC26A9	2.17e-03	11	120	2	PS50801
Domain	STAS	SLC26A2 SLC26A9	2.17e-03	11	120	2	PF01740
Domain	SLC26A/SulP_fam	SLC26A2 SLC26A9	2.17e-03	11	120	2	IPR001902
Domain	STAS_dom	SLC26A2 SLC26A9	2.17e-03	11	120	2	IPR002645
Domain	SLC26A/SulP_dom	SLC26A2 SLC26A9	2.17e-03	11	120	2	IPR011547
Domain	-	RARS1 LARS1	2.17e-03	11	120	2	1.10.730.10
Domain	-	SLC26A2 SLC26A9	2.17e-03	11	120	2	3.30.750.24
Domain	Sulfate_transp	SLC26A2 SLC26A9	2.17e-03	11	120	2	PF00916
Domain	-	RANBP2 NAA15 UNC45A MTOR CFAP46 NAA16	2.21e-03	207	120	6	1.25.40.10
Domain	Pkinase_C	LATS1 PRKCE PRKCQ	2.47e-03	42	120	3	PF00433
Domain	TPR_1	RANBP2 NAA15 UNC45A NAA16	2.71e-03	90	120	4	IPR001440
Domain	TPR_1	RANBP2 NAA15 UNC45A NAA16	2.71e-03	90	120	4	PF00515
Domain	-	MCCC1 CPS1	3.05e-03	13	120	2	3.40.50.20
Domain	KAZAL	FSTL4 WFIKKN1 WFIKKN2	3.21e-03	46	120	3	SM00280
Domain	ATP_GRASP	MCCC1 CPS1	3.54e-03	14	120	2	PS50975
Domain	ATP-grasp	MCCC1 CPS1	3.54e-03	14	120	2	IPR011761
Domain	PreATP-grasp_dom	MCCC1 CPS1	3.54e-03	14	120	2	IPR016185
Domain	TPR-like_helical_dom	RANBP2 NAA15 UNC45A MTOR CFAP46 NAA16	3.96e-03	233	120	6	IPR011990
Domain	KAZAL_2	FSTL4 WFIKKN1 WFIKKN2	4.07e-03	50	120	3	PS51465
Domain	TPR_2	NAA15 UNC45A NAA16	4.07e-03	50	120	3	PF07719
Domain	TPR_2	NAA15 UNC45A NAA16	4.07e-03	50	120	3	IPR013105
Domain	-	MCCC1 CPS1	4.07e-03	15	120	2	3.30.1490.20
Domain	Kazal_dom	FSTL4 WFIKKN1 WFIKKN2	4.30e-03	51	120	3	IPR002350
Domain	WAP	WFIKKN1 WFIKKN2	4.63e-03	16	120	2	SM00217
Domain	WAP	WFIKKN1 WFIKKN2	4.63e-03	16	120	2	PF00095
Domain	-	WFIKKN1 WFIKKN2	5.23e-03	17	120	2	4.10.75.10
Domain	WAP	WFIKKN1 WFIKKN2	5.23e-03	17	120	2	PS51390
Domain	aa-tRNA-synth_I_CS	RARS1 LARS1	5.86e-03	18	120	2	IPR001412
Domain	ATP_grasp_subdomain_1	MCCC1 CPS1	5.86e-03	18	120	2	IPR013815
Domain	-	MCCC1 CPS1	5.86e-03	18	120	2	3.30.470.20
Domain	KU	WFIKKN1 WFIKKN2	5.86e-03	18	120	2	SM00131
Domain	-	WFIKKN1 WFIKKN2	5.86e-03	18	120	2	4.10.410.10
Domain	Prtase_inh_Kunz-CS	WFIKKN1 WFIKKN2	5.86e-03	18	120	2	IPR020901
Domain	C1_1	PRKCE PRKCQ UNC13A	5.88e-03	57	120	3	PF00130
Domain	Ion_trans_dom	CATSPER1 TRPV2 TRPM1 CNGA2	6.28e-03	114	120	4	IPR005821
Domain	Ion_trans	CATSPER1 TRPV2 TRPM1 CNGA2	6.28e-03	114	120	4	PF00520
Pathway	BIOCARTA_IRES_PATHWAY	EIF4G1 EIF4G2 EIF4G3	1.15e-05	7	99	3	M22028
Pathway	BIOCARTA_MTOR_PATHWAY	MTOR EIF4G1 EIF4G2 EIF4G3	1.52e-05	22	99	4	M16563
Pathway	BIOCARTA_EIF4_PATHWAY	MTOR EIF4G1 EIF4G2 EIF4G3	2.18e-05	24	99	4	M4791
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	KRT6A KRT6B RANBP2 NAA15 HK2 RARS1 SPTAN1 LARS1 UNC45A CPS1 KRR1 MDH2 SLC25A22 PARP1 RUVBL1 KRT6C SYNE2 POP1 EIF4G1 EIF4G2 ECI2 NMT1 SNRPG	1.05e-09	1415	124	23	28515276
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KRT6A MYH4 KRT6B RANBP2 ABCB5 SPTAN1 GRK5 DNAH2 HKDC1 CHD3 MDH2 SLC25A22 PARP1 LATS1 GUCY1A2 KRT6C RNPS1 SYNE2 EIF4G1 EIF4G3 HSPA2 PCID2 CFAP46	1.50e-09	1442	124	23	35575683
Pubmed	eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy.	MTOR EIF4G1 EIF4G2 EIF4G3	2.30e-09	6	124	4	18426977
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	RANBP2 RARS1 SPTAN1 LARS1 IDH1 UNC45A MDH2 TRIP4 SLC25A22 CRYL1 PARP1 IGBP1 LATS1 AKAP9 RUVBL1 RNPS1 POP1 EIF4G1 EIF4G2 RASSF8 PCID2	3.32e-09	1247	124	21	27684187
Pubmed	eIF4G is required for the pioneer round of translation in mammalian cells.	NCBP2 EIF4G1 EIF4G2 EIF4G3	1.91e-08	9	124	4	15361857
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	RANBP2 HK2 RARS1 SPTAN1 LARS1 CHD3 GATAD2B PARP1 RUVBL1 EIF4G1 EIF4G2	3.30e-08	332	124	11	32786267
Pubmed	Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay.	KRT6A KRT6B KRT6C	4.42e-08	3	124	3	29357356
Pubmed	Cloning and characterization of multiple human genes and cDNAs encoding highly related type II keratin 6 isoforms.	KRT6A KRT6B KRT6C	4.42e-08	3	124	3	7543104
Pubmed	The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53.	RARS1 SPTAN1 PARP1 RUVBL1 EIF4G1 EIF4G3	7.02e-08	59	124	6	32382008
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	NAA15 HK2 SPTAN1 LARS1 CHD3 CHD1L IDH1 PARP1 ARL2 RUVBL1 MTOR EIF4G1 EIF4G2	7.23e-08	538	124	13	28524877
Pubmed	Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.	KRT6B RANBP2 HK2 RARS1 SPTAN1 LARS1 CHD3 NCBP2 PARP1 RUVBL1 KRT6C RNPS1 EIF4G1 EIF4G2	7.67e-08	641	124	14	36057605
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	KRT6A RARS1 ANXA6 SPTAN1 CHD3 CHD1L UNC45A KRR1 MDH2 TRIP4 NCBP2 PARP1 ARL2 AKAP9 RUVBL1 RNPS1 POP1 EIF4G1 TRPM1 NMT1	8.67e-08	1371	124	20	36244648
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	KRT6A KRT6B RARS1 GLB1L LARS1 FSTL4 CHD3 KRR1 MDH2 GATAD2B NCBP2 PARP1 RUVBL1 KRT6C POP1 ZW10 HSPA2 SNRPG	1.53e-07	1153	124	18	29845934
Pubmed	A Synaptotagmin Isoform Switch during the Development of an Identified CNS Synapse.	SYT2 SYT1 SYT5	1.76e-07	4	124	3	27210552
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	RANBP2 HK2 PSMG3 ANXA6 SPTAN1 LARS1 UNC45A MCCC1 KRR1 MDH2 HPSE CLCC1 PARP1 MTOR SYNE2 POP1 EIF4G1 EIF4G2 ZW10 HSPA2	1.90e-07	1440	124	20	30833792
Pubmed	mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.	NAA15 HK2 RARS1 LARS1 IDH1 UNC45A RUVBL1 KRT6C MTOR EIF4G1	1.94e-07	312	124	10	37120454
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	RANBP2 NAA15 HK2 RARS1 LARS1 DNAH2 UNC45A CLCC1 SLC25A22 VPS52 MTOR EIF4G1 EIF4G2 ZW10 EIF4G3 HSPA2	2.62e-07	942	124	16	31073040
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	KRT6B RANBP2 NAA15 HK2 RARS1 SPTAN1 LARS1 CHD1L UNC45A MCCC1 KRR1 SLC25A22 PARP1 RUVBL1 RNPS1 POP1 EIF4G1 EIF4G2 PCID2	3.38e-07	1353	124	19	29467282
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	NAA15 RARS1 ANXA6 SPTAN1 LARS1 DNAH2 HKDC1 CHD3 MDH2 PARP1 RUVBL1 EIF4G1 EIF4G3 HSPA2 SNRPG	3.78e-07	847	124	15	35235311
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	RANBP2 ANXA6 BSDC1 UNC45A MCCC1 TEX9 CLCC1 VPS52 LATS1 RUVBL1 EIF4G2 RASSF8 NMT1 HSPA2 PCID2	4.13e-07	853	124	15	28718761
Pubmed	Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E.	EIF4G1 EIF4G2 EIF4G3	4.40e-07	5	124	3	9878069
Pubmed	Pachyonychia Congenita	KRT6A KRT6B KRT6C	4.40e-07	5	124	3	20301457
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	RANBP2 NAA15 RARS1 SPTAN1 LARS1 UNC45A PARP1 RUVBL1 MTOR EIF4G1 EIF4G2 ZW10 HSPA2	5.03e-07	638	124	13	33239621
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	MYH4 RANBP2 RARS1 SPTAN1 CCDC80 UNC45A MDH2 SORCS1 NCBP2 RUVBL1 MTOR ECI2 ZW10	5.89e-07	647	124	13	26618866
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	RANBP2 NAA15 HK2 RARS1 SPTAN1 BSDC1 MCCC1 SLC1A2 GATAD2B RUVBL1 SPHKAP EIF4G2 SLC39A6 SYT1 EIF4G3 HSPA2 UNC13A	6.52e-07	1139	124	17	36417873
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	RANBP2 HK2 RARS1 ANXA6 SPTAN1 LARS1 UNC45A KRR1 MDH2 LAP3 SLC25A22 PARP1 RAB9A RUVBL1 RNPS1 MTOR EIF4G1 EIF4G2 KIF3C	7.37e-07	1425	124	19	30948266
Pubmed	Phospholipid composition dependence of Ca2+-dependent phospholipid binding to the C2A domain of synaptotagmin IV.	SYT2 SYT1 SYT5	8.78e-07	6	124	3	8626542
Pubmed	Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo.	EIF4G1 EIF4G2 EIF4G3	8.78e-07	6	124	3	10022874
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	KRT6B RANBP2 RARS1 LARS1 CHD1L MCCC1 KRR1 LAP3 NCBP2 PARP1 ARL2 VPS52 RUVBL1 RNPS1 POP1 EIF4G1 PRKCQ PCID2	1.06e-06	1318	124	18	30463901
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	RANBP2 NAA15 LARS1 CHD3 IDH1 UNC45A MCCC1 MDH2 PARP1 IGBP1 RUVBL1 RNPS1 EIF4G2 EIF4G3 NMT1	1.28e-06	934	124	15	33916271
Pubmed	The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.	KRT6A KRT6B RARS1 LARS1 CHD3 MCCC1 CPS1 GATAD2B EIF4G2	1.32e-06	298	124	9	30737378
Pubmed	Multiple roles for the C-terminal domain of eIF5 in translation initiation complex assembly and GTPase activation.	NCBP2 EIF4G1 EIF4G2	1.53e-06	7	124	3	11331597
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	KRT6B RANBP2 NAA15 KMT2B RARS1 SPTAN1 IDH1 PARP1 RUVBL1 EIF4G1 ECI2 NMT1 PCID2	1.68e-06	711	124	13	33022573
Pubmed	Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.	KRT6A LARS1 GATAD2B AKAP9 SYNE2 EIF4G1	1.75e-06	101	124	6	26949739
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	RANBP2 RARS1 ANXA6 LARS1 GATAD2B PARP1 LATS1 RUVBL1 POP1 EIF4G2	1.80e-06	399	124	10	37536630
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	SPTAN1 SYT2 MCCC1 MDH2 SLC1A2 GATAD2B SLC25A22 MTOR SYT1 PRKCE SYT5 HSPA2	2.45e-06	621	124	12	22794259
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	COL3A1 KRT6A KRT6B NAA15 RARS1 SPTAN1 LARS1 LAMA3 UNC45A KRR1 SLC25A22 PARP1 RUVBL1 RNPS1 POP1 EIF4G1 NMT1	2.48e-06	1257	124	17	36526897
Pubmed	Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.	RANBP2 POGLUT3 RARS1 ANXA6 SPTAN1 LARS1 IDH1 MCCC1 MDH2 LAP3 PARP1 EIF4G2 HSPA2 ARHGAP19	2.50e-06	859	124	14	31536960
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NAA15 SPTAN1 UNC45A MCCC1 LATS1 AKAP9 MTOR SYNE2 EIF4G1 PRKCE RASSF8 EIF4G3 BICC1 ARHGAP19	2.57e-06	861	124	14	36931259
Pubmed	Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.	SPTAN1 DNAH2 UNC45A PARP1 RUVBL1 POP1 EIF4G1 EIF4G3	2.95e-06	245	124	8	21182205
Pubmed	The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.	KRT6B RANBP2 LARS1 MCCC1 MDH2 PARP1 RUVBL1 EIF4G1 EIF4G3	3.05e-06	330	124	9	32529326
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	MPV17 SPTAN1 LARS1 DNAH2 UNC45A MDH2 SORCS1 SLC25A22 PARP1 RUVBL1 SYNE2 EIF4G1 PCID2	3.18e-06	754	124	13	35906200
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	KRT6A KRT6B MTERF1 SPTAN1 LARS1 CHD3 MDH2 SLC1A2 SLC25A22 PARP1 GUCY1A2 EIF4G1 EIF4G2 SYT1 PRKCE EIF4G3 HSPA2 UNC13A	3.37e-06	1431	124	18	37142655
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	RANBP2 NAA15 RARS1 SPTAN1 LARS1 IDH1 UNC45A MDH2 LAP3 PARP1 RUVBL1 EIF4G1 ZW10 EIF4G3 NMT1 HSPA2	3.48e-06	1149	124	16	35446349
Pubmed	GASP-2 overexpressing mice exhibit a hypermuscular phenotype with contrasting molecular effects compared to GASP-1 transgenics.	MYH4 WFIKKN1 WFIKKN2	3.66e-06	9	124	3	31960486
Pubmed	Distinct developmental expression of synaptotagmin I and IX in the mouse brain.	SYT2 SYT1 SYT5	3.66e-06	9	124	3	16407767
Pubmed	Mirror image motifs mediate the interaction of the COOH terminus of multiple synaptotagmins with the neurexins and calmodulin.	SYT2 SYT1 SYT5	3.66e-06	9	124	3	8901523
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	RANBP2 RARS1 SPTAN1 CHD3 UNC45A RUVBL1 EIF4G1 EIF4G2	4.08e-06	256	124	8	33397691
Pubmed	Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion.	SYT2 SYT1 SYT5	5.21e-06	10	124	3	9914469
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	NAA15 RARS1 ANXA6 UNC45A CPS1 MDH2 PARP1 EIF4G2 ZW10 NMT1	5.33e-06	451	124	10	36168627
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	RANBP2 RUVBL1 SYNE2 EIF4G1 EIF4G2 EIF4G3	5.50e-06	123	124	6	26912792
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	RANBP2 RARS1 LARS1 CHD3 KRR1 MDH2 TRIP4 GATAD2B NCBP2 SLC25A22 PARP1 RUVBL1 RNPS1 POP1 EIF4G1 EIF4G2 HSPA2	5.51e-06	1335	124	17	29229926
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	RANBP2 SPTAN1 BSDC1 UNC45A CLCC1 IGBP1 SYNE2 EIF4G1 EIF4G2 ZW10 PCID2	6.42e-06	568	124	11	37774976
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	RARS1 SPTAN1 LARS1 IDH1 MCCC1 MDH2 PARP1 AKAP9 RUVBL1 POP1 EIF4G1 NMT1 HSPA2	6.62e-06	807	124	13	30575818
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	MGAT4B PSMG3 GRK5 BSDC1 CCDC80 CHD1L CPS1 NCBP2 ARL2 PIEZO2 CCZ1 WFIKKN1 RNF146 EIF4G3 HSPA2 CFAP46	7.03e-06	1215	124	16	15146197
Pubmed	SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms.	SYT2 SYT1 SYT5	7.15e-06	11	124	3	10734137
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	RANBP2 NAA15 ANXA6 IDH1 MCCC1 MDH2 LAP3 CLCC1 PARP1 ARL2 IGBP1 RUVBL1 MTOR SYNE2 EIF4G1 EIF4G2 NMT1	7.51e-06	1367	124	17	32687490
Pubmed	KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II.	RARS1 LARS1 MCCC1 KRR1 NCBP2 RUVBL1 KRT6C POP1	8.06e-06	281	124	8	26725010
Pubmed	Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics.	KRT6B RARS1 CHD3 GATAD2B PARP1 RUVBL1 POP1 EIF4G1 SNRPG	1.03e-05	384	124	9	31059266
Pubmed	Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.	KRT6A KRT6B RARS1 SPTAN1 LAMA3 MCCC1 PARP1 RUVBL1 KRT6C HSPA2	1.06e-05	488	124	10	31324722
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	CCZ1B KRT6B RANBP2 HK2 RARS1 LARS1 CHD1L UNC45A SLC25A22 PARP1 IGBP1 RUVBL1 CCZ1 EIF4G1 HSPA2 PCID2	1.07e-05	1257	124	16	37317656
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	KRT6A KRT6B CHD3 KRR1 TRIP4 GATAD2B PARP1 RUVBL1 KRT6C EIF4G1 EIF4G2	1.16e-05	605	124	11	28977666
Pubmed	Multiple isoforms of the translation initiation factor eIF4GII are generated via use of alternative promoters, splice sites and a non-canonical initiation codon.	EIF4G1 EIF4G2	1.26e-05	2	124	2	22909319
Pubmed	Expression, purification and characterization of the second Kunitz-type protease inhibitor domain of the human WFIKKN protein.	WFIKKN1 WFIKKN2	1.26e-05	2	124	2	12709070
Pubmed	Activation of the PI3K/mTOR Pathway following PARP Inhibition in Small Cell Lung Cancer.	PARP1 MTOR	1.26e-05	2	124	2	27055253
Pubmed	Investigation of Novel Regulation of N-myristoyltransferase by Mammalian Target of Rapamycin in Breast Cancer Cells.	MTOR NMT1	1.26e-05	2	124	2	30154572
Pubmed	Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle.	KRT6A KRT6B	1.26e-05	2	124	2	10550543
Pubmed	The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis.	KRT6A KRT6B	1.26e-05	2	124	2	10550545
Pubmed	PARP-1 modulation of mTOR signaling in response to a DNA alkylating agent.	PARP1 MTOR	1.26e-05	2	124	2	23110147
Pubmed	Distinct modes of endocytotic presynaptic membrane and protein uptake at the calyx of Held terminal of rats and mice.	SYT2 UNC13A	1.26e-05	2	124	2	27154627
Pubmed	Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells.	SYT2 SYT1	1.26e-05	2	124	2	14504267
Pubmed	The two functional keratin 6 genes of mouse are differentially regulated and evolved independently from their human orthologs.	KRT6A KRT6B	1.26e-05	2	124	2	9790766
Pubmed	mTOR may interact with PARP-1 to regulate visible light-induced parthanatos in photoreceptors.	PARP1 MTOR	1.26e-05	2	124	2	32066462
Pubmed	Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions.	EIF4G1 EIF4G3	1.26e-05	2	124	2	31999954
Pubmed	Synaptotagmins 1 and 2 as mediators of rapid exocytosis at nerve terminals: the dyad hypothesis.	SYT2 SYT1	1.26e-05	2	124	2	23648184
Pubmed	The chromatin remodeler ALC1 underlies resistance to PARP inhibitor treatment.	CHD1L PARP1	1.26e-05	2	124	2	33355125
Pubmed	Discovery of a novel murine keratin 6 (K6) isoform explains the absence of hair and nail defects in mice deficient for K6a and K6b.	KRT6A KRT6B	1.26e-05	2	124	2	11489919
Pubmed	eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation.	EIF4G1 EIF4G3	1.26e-05	2	124	2	10872469
Pubmed	Translation of mRNAs from vesicular stomatitis virus and vaccinia virus is differentially blocked in cells with depletion of eIF4GI and/or eIF4GII.	EIF4G1 EIF4G2	1.26e-05	2	124	2	19769989
Pubmed	Introducing a null mutation in the mouse K6alpha and K6beta genes reveals their essential structural role in the oral mucosa.	KRT6A KRT6B	1.26e-05	2	124	2	10953016
Pubmed	Human cytomegalovirus infection induces rapamycin-insensitive phosphorylation of downstream effectors of mTOR kinase.	MTOR EIF4G1	1.26e-05	2	124	2	15452223
Pubmed	The complete cDNA and deduced amino acid sequence of a type II mouse epidermal keratin of 60,000 Da: analysis of sequence differences between type I and type II keratins.	KRT6A KRT6B	1.26e-05	2	124	2	6207530
Pubmed	Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained mice.	PRKCE PRKCQ	1.26e-05	2	124	2	36456864
Pubmed	Synaptotagmin I and II are present in distinct subsets of central synapses.	SYT2 SYT1	1.26e-05	2	124	2	17492637
Pubmed	Modulation of poly(ADP-ribose) polymerase-1 (PARP-1)-mediated oxidative cell injury by ring finger protein 146 (RNF146) in cardiac myocytes.	PARP1 RNF146	1.26e-05	2	124	2	24842055
Pubmed	Multiple roles for PARP1 in ALC1-dependent nucleosome remodeling.	CHD1L PARP1	1.26e-05	2	124	2	34465625
Pubmed	Differential implication of protein kinase C isoforms in cytotoxic T lymphocyte degranulation and TCR-induced Fas ligand expression.	PRKCE PRKCQ	1.26e-05	2	124	2	14645153
Pubmed	CHD1L: a new candidate gene for congenital anomalies of the kidneys and urinary tract (CAKUT).	CHD1L PARP1	1.26e-05	2	124	2	22146311
Pubmed	5'-UTR recruitment of the translation initiation factor eIF4GI or DAP5 drives cap-independent translation of a subset of human mRNAs.	EIF4G1 EIF4G2	1.26e-05	2	124	2	32571876
Pubmed	A reporter transgene based on a human keratin 6 gene promoter is specifically expressed in the periderm of mouse embryos.	KRT6A KRT6B	1.26e-05	2	124	2	11118885
Pubmed	Distinct expression pattern of two related human proteins containing multiple types of protease-inhibitory modules.	WFIKKN1 WFIKKN2	1.26e-05	2	124	2	11928817
Pubmed	Activation of the SNF2 family ATPase ALC1 by poly(ADP-ribose) in a stable ALC1·PARP1·nucleosome intermediate.	CHD1L PARP1	1.26e-05	2	124	2	23132853
Pubmed	Palmitate-activated macrophages confer insulin resistance to muscle cells by a mechanism involving protein kinase C θ and ε.	PRKCE PRKCQ	1.26e-05	2	124	2	22046423
Pubmed	eIF4G-driven translation initiation of downstream ORFs in mammalian cells.	MTOR EIF4G1	1.26e-05	2	124	2	32941651
Pubmed	Cleavage of eukaryotic translation initiation factor 4GII within foot-and-mouth disease virus-infected cells: identification of the L-protease cleavage site in vitro.	EIF4G2 EIF4G3	1.26e-05	2	124	2	15016848
Pubmed	Collapse of the keratin filament network through the expression of mutant keratin 6c observed in a case of focal plantar keratoderma.	KRT6A KRT6C	1.26e-05	2	124	2	23662636
Pubmed	Elevated Hexokinase II Expression Confers Acquired Resistance to 4-Hydroxytamoxifen in Breast Cancer Cells.	HK2 MTOR	1.26e-05	2	124	2	31519767
Pubmed	The N-terminal half of the heavy chain of botulinum type A neurotoxin forms channels in planar phospholipid bilayers.	SYT2 SYT1	1.26e-05	2	124	2	2446925
Pubmed	Inositol-1,3,4,5-tetrakisphosphate binding to C2B domain of IP4BP/synaptotagmin II.	SYT2 SYT1	1.26e-05	2	124	2	7961887
Pubmed	Synaptotagmins I and II act as nerve cell receptors for botulinum neurotoxin G.	SYT2 SYT1	1.26e-05	2	124	2	15123599
Cytoband	17p13.1	MYH4 PHF23 DNAH2 CHD3 ALOX15B	1.82e-05	118	124	5	17p13.1
Cytoband	7q21-q22	MTERF1 AKAP9	3.21e-04	10	124	2	7q21-q22
GeneFamily	Synaptotagmins	SYT2 SYT1 SYT5	5.42e-05	17	80	3	765
GeneFamily	Keratins, type II	KRT6A KRT6B KRT6C	2.26e-04	27	80	3	609
GeneFamily	C2 domain containing protein kinases	PRKCE PRKCQ	8.50e-04	10	80	2	835
GeneFamily	N(alpha)-acetyltransferase subunits\|GCN5 related N-acetyltransferases	NAA15 NAA16	1.24e-03	12	80	2	660
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	TRIP4 PARP1	1.96e-03	15	80	2	26
GeneFamily	Myosin heavy chains	MYH4 MYH16	1.96e-03	15	80	2	1098
GeneFamily	Parkinson disease associated genes	EIF4G1 PLA2G6	2.23e-03	16	80	2	672
GeneFamily	WAP four-disulfide core domain containing\|Fibronectin type III domain containing	WFIKKN1 WFIKKN2	2.83e-03	18	80	2	361
GeneFamily	Aminoacyl tRNA synthetases, Class I	RARS1 LARS1	3.15e-03	19	80	2	131
GeneFamily	Transient receptor potential cation channels	TRPV2 TRPM1	6.78e-03	28	80	2	249
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	AKAP9 SPHKAP	7.26e-03	29	80	2	396
GeneFamily	PHD finger proteins	KMT2B PHF23 CHD3	7.43e-03	90	80	3	88
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	ARL17A ARL2	8.27e-03	31	80	2	357
Coexpression	HOUNKPE_HOUSEKEEPING_GENES	CCZ1B RANBP2 SPG7 PSMG3 LARS1 BSDC1 TRIP4 GATAD2B NCBP2 PARP1 IGBP1 VPS52 RAB9A RUVBL1 CCZ1 RNPS1 MTOR EIF4G2 SLC39A6 NMT1	4.52e-07	1158	123	20	MM1338
Coexpression	HOUNKPE_HOUSEKEEPING_GENES	RANBP2 SPG7 PSMG3 LARS1 BSDC1 TRIP4 GATAD2B NCBP2 PARP1 IGBP1 VPS52 RAB9A RUVBL1 CCZ1 RNPS1 MTOR EIF4G2 SLC39A6 NMT1	1.33e-06	1129	123	19	M42508
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYH4 GRK5 CCDC80 F8 GUCY1A2 PLA2G5 BICC1	7.98e-07	182	124	7	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	Basal_cells\|World / lung cells shred on cell class, cell subclass, sample id	KRT6A CCDC80 CEMIP S100A2 NYNRIN SYNE2 SNCG	1.35e-06	197	124	7	24360b660000bdfb999d58fbf4e29585a97e1785
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6A KRT6B LAMA3 TRIM7 CEMIP S100A2 KRT6C	1.35e-06	197	124	7	2430f31d9312338e0ca23bfc6bdb0365340860fd
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORCS1 CEMIP WFIKKN1 CNGA2	5.67e-06	42	124	4	56bbec86001d43cc2c71d4dcd70b22ea41963fad
ToppCell	356C-Fibroblasts-Fibroblast-E-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL3A1 POGLUT3 CCDC80 CPS1 RASSF8 BICC1	1.07e-05	178	124	6	a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 KRT6A CCDC80 SLC1A2 CNGA2 BICC1	1.07e-05	178	124	6	6d9ecfaeb50d562899380de379ebf7b99fd8adc9
ToppCell	356C-Fibroblasts-Fibroblast-E\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL3A1 POGLUT3 CCDC80 CPS1 RASSF8 BICC1	1.07e-05	178	124	6	371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 KRT6A CCDC80 SLC1A2 CNGA2 BICC1	1.07e-05	178	124	6	d3f518cd75b02e85d45cbb9b2eff30f0272512a8
ToppCell	ASK428-Epithelial-Transformed_epithelium\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	COL3A1 PSMG3 ABCB5 CCDC80 CPS1 BICC1	1.50e-05	189	124	6	87189275234b5d59484c58acbb14a09903f2b578
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 GRK5 SLC1A2 PIEZO2 GUCY1A2 SYT1	1.55e-05	190	124	6	2306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 GRK5 SLC1A2 PIEZO2 GUCY1A2 SYT1	1.55e-05	190	124	6	1f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CPS1 SLC1A2 S100A2 AKAP9 SPHKAP SNCG	1.55e-05	190	124	6	498bbe063bc75d323cb186a82cce122b511d2cff
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 GRK5 SLC1A2 PIEZO2 GUCY1A2 SYT1	1.59e-05	191	124	6	a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 GRK5 SLC1A2 PIEZO2 GUCY1A2 SYT1	1.64e-05	192	124	6	9093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 GRK5 SLC1A2 PIEZO2 GUCY1A2 SYT1	1.64e-05	192	124	6	9ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell	RV-02._Fibroblast_II\|RV / Chamber and Cluster_Paper	COL3A1 GRK5 CCDC80 PLA2G5 RASSF8 BICC1	1.74e-05	194	124	6	11c79a8c56ece42713b04b321982e41e239f07a5
ToppCell	droplet-Tongue-nan-3m-Epithelial-keratinocyte\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT6A HK2 CRYL1 AKAP9 SYNE2 SLC39A6	1.74e-05	194	124	6	592e8c4b73ba424a52305ac411ea9c0a2dc44467
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 GRK5 SLC1A2 PIEZO2 GUCY1A2 SYT1	1.79e-05	195	124	6	d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 GRK5 SLC1A2 PIEZO2 GUCY1A2 SYT1	1.79e-05	195	124	6	803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	COL3A1 GRK5 CCDC80 TOP6BL PLA2G5 BICC1	1.79e-05	195	124	6	a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 GRK5 SLC1A2 PIEZO2 GUCY1A2 SYT1	1.79e-05	195	124	6	4f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 GRK5 SLC1A2 PIEZO2 GUCY1A2 SYT1	1.85e-05	196	124	6	a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell	Basal_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	KRT6A CEMIP S100A2 NYNRIN SYNE2 SNCG	1.85e-05	196	124	6	3b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	COL3A1 GRK5 CCDC80 PIEZO2 SPHKAP SNCG	1.85e-05	196	124	6	22538376a95fe3afe8639a216a5497087aa94110
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 GRK5 SLC1A2 PIEZO2 GUCY1A2 SYT1	1.85e-05	196	124	6	3e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 GRK5 SLC1A2 PIEZO2 GUCY1A2 SYT1	1.90e-05	197	124	6	6d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 GRK5 SLC1A2 PIEZO2 GUCY1A2 SYT1	1.90e-05	197	124	6	b349f8e96d61a4c296af64711e11fc44459a9413
ToppCell	Bronchus_Control_(B.)\|World / Sample group, Lineage and Cell type	KRT6A KRT6B SLC26A2 TRIM7 S100A2 HSPA2	1.90e-05	197	124	6	b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 GRK5 SLC1A2 PIEZO2 GUCY1A2 SYT1	1.90e-05	197	124	6	c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell	Bronchial_Biopsy\|World / Tissue, Lineage and Cell class of Lung Cells from 10X	KRT6A LAMA3 S100A2 AKAP9 SYNE2 HSPA2	1.95e-05	198	124	6	f5b7013045b61fc56894f80092f799770dde1c8f
ToppCell	metastatic_Brain-Fibroblasts-FB-like_cells\|metastatic_Brain / Location, Cell class and cell subclass	COL3A1 CCDC80 CEMIP PIEZO2 PLA2G5 BICC1	2.01e-05	199	124	6	12133087eae9f0e9b6c13a71e8187117768e64ce
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-T/NK-dn_T\|Leuk-UTI / Disease, condition lineage and cell class	BSDC1 HKDC1 RUVBL1 TRPV2 PRKCQ ZW10	2.01e-05	199	124	6	aa4d8ce8994e5032a33d5cc68c482882147cdc3b
ToppCell	proximal-mesenchymal-Vascular_Smooth_Muscle-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 ANXA6 GRK5 GUCY1A2 SNCG HSPA2	2.07e-05	200	124	6	5c0135d3cb6f7fa904e9760904dfe5f11c7e9102
ToppCell	proximal-3-mesenchymal-Vascular_Smooth_Muscle\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 ANXA6 GRK5 GUCY1A2 SNCG HSPA2	2.07e-05	200	124	6	870ab11343711f64fe6d6a858fc420fe17f1636a
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	SPTAN1 GATAD2B KIF3C SNCG EIF4G3 UNC13A	2.07e-05	200	124	6	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Cortical_neuron\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	SPTAN1 IDH1 SLC1A2 SYT1 SYT5 KIF3C	2.07e-05	200	124	6	458fb0f40c1720f1cacedf78c40bd059692bfc62
ToppCell	proximal-mesenchymal-Vascular_Smooth_Muscle\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL3A1 ANXA6 GRK5 GUCY1A2 SNCG HSPA2	2.07e-05	200	124	6	22892afca3666e944102c231b3f10340d8391364
ToppCell	Basal_cells-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	FSTL4 S100A2 NYNRIN SYT1 SNCG	7.36e-05	155	124	5	30accc72a6a914ae0c4d52b373ea1c9a98efbf22
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT2_Precursor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	LAMA3 HKDC1 SLC26A9 CPS1 MAPK13	7.36e-05	155	124	5	9cad73d0b8ead289e1073d1a2e00bbeb1228308c
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	FSTL4 LAMA3 GUCY1A2 TRPV2 PLA2G5	8.55e-05	160	124	5	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 KRT6A CCDC80 CNGA2 BICC1	8.55e-05	160	124	5	8590281165eab6514a9f6a022b900d4c222c1044
ToppCell	Thalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a7\|Thalamus / BrainAtlas - Mouse McCarroll V32	MYH4 MDH2 WFIKKN2 TRPM1 SNCG	8.55e-05	160	124	5	7d34159363d274019e14549d1186c629ce990691
ToppCell	Thalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a7-Tac2\|Thalamus / BrainAtlas - Mouse McCarroll V32	MYH4 MDH2 WFIKKN2 TRPM1 SNCG	8.55e-05	160	124	5	fe5fb0e7a79862f63529721f0a82f4f6d231d3ca
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HK2 HKDC1 PGC SLC1A2 ALOX15B	9.61e-05	164	124	5	b0ed8cb6000ce8bf94444307e4b7b3574fa3fab2
ToppCell	367C-Epithelial_cells-Epithelial-A_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HK2 HKDC1 PGC SLC1A2 ALOX15B	9.61e-05	164	124	5	3aea6207a011ad55a1aeb2ed9fb54d31b23694b5
ToppCell	356C-Fibroblasts-Fibroblast-H-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL3A1 ABCB5 CCDC80 CEMIP BICC1	1.08e-04	168	124	5	b5d74500bdac0d680ce7eb7afa0b867b8d85e6a4
ToppCell	356C-Fibroblasts-Fibroblast-H\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL3A1 ABCB5 CCDC80 CEMIP BICC1	1.08e-04	168	124	5	838ce47d4958ba12047882f97925eddd02f081c7
ToppCell	RA-01._Fibroblast_I\|RA / Chamber and Cluster_Paper	MYH4 CCDC80 SORCS1 PLA2G5 BICC1	1.11e-04	169	124	5	6373562ab3b1765060212a6a53d6543e7e942e80
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-6\|TCGA-Bladder / Sample_Type by Project: Shred V9	KRT6A KRT6B TRIM7 S100A2 KRT6C	1.17e-04	171	124	5	0e78389f8f3d54570a6deb3dd307b865b46307e9
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 SLC26A2 HKDC1 SYNE2 NMT1	1.23e-04	173	124	5	e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCell	facs-Large_Intestine-Proximal-3m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 SLC26A2 HKDC1 SYNE2 NMT1	1.23e-04	173	124	5	99532bb768ee35fed939a377acb5215d3f8904bd
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 GRK5 SYNE2 SYT5 BICC1	1.23e-04	173	124	5	c63a615998d13b1725b5767f4ad2ec7e2b61db68
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 HUS1B F8 TRPV2 SNCG	1.30e-04	175	124	5	90302e8a44858ef3b2a165b88284d4788d591a99
ToppCell	facs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA3 GUCY1A2 WFIKKN2 SYT5 SNCG	1.30e-04	175	124	5	d8e385320f554d974538b7cdc4f8e4767f1455f2
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Adult / Lineage, Cell type, age group and donor	FSTL4 PIEZO2 SPHKAP SYT1 UNC13A	1.30e-04	175	124	5	4db1a3c284488b3f6de7568363f176d74e2a4587
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231\|Adult / Lineage, Cell type, age group and donor	FSTL4 PIEZO2 SPHKAP SYT1 UNC13A	1.30e-04	175	124	5	8d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell	facs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA3 GUCY1A2 WFIKKN2 SYT5 SNCG	1.30e-04	175	124	5	cf15465855602ba135752c18755e3e058dbd42ec
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL3A1 CCDC80 PIEZO2 GUCY1A2 BICC1	1.37e-04	177	124	5	cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-5\|TCGA-Lung / Sample_Type by Project: Shred V9	KRT6A KRT6B TRIM7 S100A2 KRT6C	1.37e-04	177	124	5	a0c7d08469c513cecf87777c19876884f1511570
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL3A1 CCDC80 SYT2 PLA2G5 BICC1	1.37e-04	177	124	5	ac90e4ce5be304a5a7473736397327010f2d1999
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL3A1 CCDC80 PIEZO2 GUCY1A2 BICC1	1.37e-04	177	124	5	db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 GRK5 SLC1A2 PIEZO2 SYT1	1.49e-04	180	124	5	280ff5c8f292be1b88120db5ff1788b750644856
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 GRK5 SLC1A2 PIEZO2 SYT1	1.49e-04	180	124	5	fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CCDC80 SORCS1 SPHKAP SYT1 BICC1	1.60e-04	183	124	5	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GRK5 F8 LAP3 WFIKKN1 PLA2G5	1.60e-04	183	124	5	ce8be9418b473ea94ec806edc7a2078cc30c1703
ToppCell	droplet-Lung-3m-Epithelial-airway_epithelial-neuroendocrine_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SYT2 SORCS1 PIEZO2 MAPK13 UNC13A	1.65e-04	184	124	5	e0e5a553fb8c0947679634396d20c2ca8455b932
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL3A1 GRK5 CCDC80 SLC1A2 GUCY1A2	1.65e-04	184	124	5	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	CTRL-Lymphoid\|CTRL / Disease state, Lineage and Cell class	ANXA6 TEX9 SYNE2 SYT1 PRKCQ	1.65e-04	184	124	5	26fb2c4e6cb9950c27eb15428e7e74e5abb4397d
ToppCell	droplet-Lung-3m-Epithelial-airway_epithelial-neuroendocrine_cell-neuroendocrine\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SYT2 SORCS1 PIEZO2 MAPK13 UNC13A	1.65e-04	184	124	5	c3b848e1438a84b3fac8a4e40f3db478cc84d970
ToppCell	tumor_Lung-Fibroblasts-Mesothelial_cells\|tumor_Lung / Location, Cell class and cell subclass	COL3A1 CCDC80 PIEZO2 KRT6C BICC1	1.65e-04	184	124	5	b0a251030d127858e68cf164be158f209a4d720f
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYH4 GRK5 CCDC80 PLA2G5 BICC1	1.69e-04	185	124	5	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	COL3A1 CCDC80 SLC1A2 GUCY1A2 BICC1	1.69e-04	185	124	5	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	moderate-Lymphoid-NK\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	COL3A1 ABCB5 SORCS1 TRPM1 RASSF8	1.69e-04	185	124	5	4979a787acbc9b4ca8defe91cc79b674e51af1bf
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 CPS1 PARP1 SYNE2 NMT1	1.73e-04	186	124	5	15ab6666748a641226e42e6ca6eeaf186a501c95
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 CPS1 PARP1 SYNE2 NMT1	1.73e-04	186	124	5	4ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCell	droplet-Marrow-BM-30m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA6 IDH1 HPSE ARHGEF10L CRYL1	1.73e-04	186	124	5	bcb3ac9f9b51346e0a2b0bda96d149b3c11f7883
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	GRK5 CCDC80 TOP6BL PLA2G5 BICC1	1.77e-04	187	124	5	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	droplet-Marrow-BM-1m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA6 IDH1 HPSE CRYL1 TRPV2	1.77e-04	187	124	5	028e7d6e1211e123879d2f353dc32fae1185dd8e
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL3A1 GRK5 CCDC80 PIEZO2 GUCY1A2	1.77e-04	187	124	5	a9316e2818217ec5feae9cf8816f7249803caee6
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D175\|Adult / Lineage, Cell type, age group and donor	COL3A1 CEMIP PIEZO2 PLA2G5 BICC1	1.77e-04	187	124	5	e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCell	(6)_ILC\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ABCB5 SORCS1 NYNRIN RASSF8 BICC1	1.82e-04	188	124	5	de7cb273899d0e0748c85f45c6b5e7f0642ab057
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RARS1 LATS1 NYNRIN RASSF8 BICC1	1.82e-04	188	124	5	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RARS1 LATS1 NYNRIN RASSF8 BICC1	1.82e-04	188	124	5	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RARS1 LATS1 NYNRIN RASSF8 BICC1	1.82e-04	188	124	5	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYH4 GRK5 CCDC80 PLA2G5 BICC1	1.82e-04	188	124	5	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	F8 PIEZO2 SYT1 KIF3C CFAP46	1.82e-04	188	124	5	524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell	ASK428-Endothelial-Lymphatic\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	CCDC80 F8 PIEZO2 KIF3C SNCG	1.82e-04	188	124	5	c371bc340966cfe9205cbf4b62c6452f49f2559f
ToppCell	5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	F8 PIEZO2 SYT1 KIF3C CFAP46	1.82e-04	188	124	5	d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCell	(6)_ILC\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ABCB5 SORCS1 NYNRIN RASSF8 BICC1	1.82e-04	188	124	5	f4734d5b703678670ece204a0519cf015e180a6e
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYT2 GUCY1A2 TRPV2 SYT5 SNCG	1.86e-04	189	124	5	de51fbd6fdb24fc4549393cf41a020005444b2aa
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 HK2 CCDC80 EIF4G2 NMT1	1.86e-04	189	124	5	6dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 CCDC80 PIEZO2 GUCY1A2 BICC1	1.86e-04	189	124	5	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 CCDC80 PIEZO2 GUCY1A2 BICC1	1.86e-04	189	124	5	e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 HK2 CCDC80 EIF4G2 NMT1	1.86e-04	189	124	5	3ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 HK2 CCDC80 EIF4G2 NMT1	1.86e-04	189	124	5	875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL3A1 CCDC80 PIEZO2 GUCY1A2 BICC1	1.86e-04	189	124	5	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	facs-Brain_Myeloid-Striatum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL3A1 HK2 CCDC80 EIF4G2 NMT1	1.86e-04	189	124	5	97ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYT2 GUCY1A2 TRPV2 SYT5 SNCG	1.91e-04	190	124	5	1d8e169d2448a34180c415843bb49aa45ed540c5
ToppCell	normal_Lung-Fibroblasts-Undetermined\|normal_Lung / Location, Cell class and cell subclass	COL3A1 ABCB5 CCDC80 GUCY1A2 BICC1	1.91e-04	190	124	5	30d4658bcc6796f0cdf54cc029f4bb904b13ef66
ToppCell	IPF-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	KRT6A LAMA3 CEMIP S100A2 SNCG	1.91e-04	190	124	5	4f15842b424eefadbfe451875e517cf70e29607f
Computational	Genes upregulated in subsets of cells of a given type within various tumors	KRT6A KRT6B LAMA3 S100A2 KRT6C	1.96e-05	50	72	5	GAVISH_3CA_METAPROGRAM_EPITHELIAL_EPI3
Drug	sodium dodecyl sulfate	KRT6A MYH4 KRT6B SLC26A2 ANXA6 KRT6C PRKCE PRKCQ	3.59e-08	91	124	8	CID000008778
Drug	glutamate	HK2 RARS1 ABCB5 LARS1 IDH1 MCCC1 CPS1 MDH2 SLC1A2 CLCC1 SLC25A22 CATSPER1 MTOR EIF4G2 TRPV2 SYT1 PRKCE PRKCQ TRPM1 MAPK13	2.52e-07	962	124	20	CID000000611
Drug	ICE inhibitor	PARP1 EIF4G1 EIF4G2 SYT1 PRKCE PRKCQ EIF4G3 MAPK13	1.39e-06	146	124	8	CID000004330
Drug	morpholine-citrate	HK2 IDH1 MDH2 LAP3	2.42e-06	18	124	4	CID000173845
Drug	SC-791	KRT6A KRT6B KRT6C	3.12e-06	6	124	3	CID010291510
Drug	icilin	SLC1A2 TRPV2 PLA2G6 TRPM1	4.67e-06	21	124	4	CID000161930
Drug	eye gene	KRT6A MYH4 KRT6B RARS1 GUCY1A2 KRT6C MTOR PRKCE PRKCQ MAPK13 ALOX15B	5.76e-06	369	124	11	CID000004782
Drug	adenosine 3',5'-cyclic phosphate	KRT6A KRT6B SYT2 IDH1 CPS1 MDH2 CLCC1 LATS1 AKAP9 GUCY1A2 KRT6C SYT1 PRKCE SYT5 PRKCQ MAPK13 SNRPG	8.70e-06	907	124	17	CID000000274
Drug	Bhg-(2-1)fuc	KRT6A KRT6B RARS1 KRT6C	9.70e-06	25	124	4	CID005287784
Drug	NSC99363	CPS1 NCBP2 MTOR EIF4G1 EIF4G2 EIF4G3	9.90e-06	90	124	6	CID000414014
Drug	UDP-FGlc	NCBP2 RNPS1 EIF4G1 EIF4G2 EIF4G3	2.23e-05	62	124	5	CID000125643
Drug	CGP57380	MTOR EIF4G2 EIF4G3 MAPK13	2.35e-05	31	124	4	CID011644425
Drug	AGN 193109	KRT6A KRT6B RARS1 KRT6C	2.35e-05	31	124	4	CID000177238
Drug	aspartate	RARS1 LARS1 IDH1 MCCC1 CPS1 MDH2 SLC1A2 LAP3 CLCC1 SLC25A22 PARP1 SYT1	2.68e-05	518	124	12	CID000000424
Drug	dimethyl maleate	SPTAN1 PARP1	2.94e-05	2	124	2	ctd:C004780
Drug	baicalein	HPSE PARP1 PRKCE PLA2G6 PRKCQ MAPK13 ALOX15B	3.04e-05	162	124	7	CID005281605
Drug	tsuwabukinonol	KRT6A KRT6B KRT6C ALOX15B	4.82e-05	37	124	4	CID006440419
Drug	chrysarobin	KRT6A KRT6B KRT6C PRKCE	4.82e-05	37	124	4	CID000068111
Disease	congenital myasthenic syndrome 7 (implicated_via_orthology)	SYT2 SYT1 SYT5	2.75e-07	4	122	3	DOID:0110659 (implicated_via_orthology)
Disease	neuromuscular junction disease (implicated_via_orthology)	SYT2 SYT1 SYT5	6.85e-07	5	122	3	DOID:439 (implicated_via_orthology)
Disease	congenital myasthenic syndrome (implicated_via_orthology)	SYT2 SYT1 SYT5	3.71e-05	16	122	3	DOID:3635 (implicated_via_orthology)
Disease	Early myoclonic encephalopathy	SLC1A2 SLC25A22	5.07e-05	3	122	2	cv:C0270855
Disease	Pachyonychia congenita syndrome	KRT6A KRT6B	1.01e-04	4	122	2	cv:C0265334
Disease	retinoblastoma (is_marker_for)	KDM1B SNCG	1.01e-04	4	122	2	DOID:768 (is_marker_for)
Disease	Pachyonychia Congenita, Jadassohn Lewandowsky Type	KRT6A KRT6B	1.01e-04	4	122	2	C1706595
Disease	pachyonychia congenita (is_implicated_in)	KRT6A KRT6B	1.01e-04	4	122	2	DOID:0050449 (is_implicated_in)
Disease	Pachyonychia Congenita, Type 2 (disorder)	KRT6A KRT6B	1.01e-04	4	122	2	C1721007
Disease	Pachyonychia Congenita	KRT6A KRT6B	1.68e-04	5	122	2	C0265334
Disease	Kyphosis deformity of spine	SLC26A2 PARP1	1.68e-04	5	122	2	C0022821
Disease	hyperinsulinemic hypoglycemia (implicated_via_orthology)	HK2 HKDC1	1.68e-04	5	122	2	DOID:13317 (implicated_via_orthology)
Disease	autoimmune disease (is_implicated_in)	IDH1 PARP1	4.67e-04	8	122	2	DOID:417 (is_implicated_in)
Disease	Malignant neoplasm of breast	SPTAN1 HPSE SORCS1 PARP1 IGBP1 AKAP9 GUCY1A2 MTOR SYNE2 POP1 SLC39A6 SNCG CNGA2	5.15e-04	1074	122	13	C0006142
Disease	X-21467 measurement	MTERF1 CPS1	5.99e-04	9	122	2	EFO_0020007
Disease	maturity-onset diabetes of the young (implicated_via_orthology)	HK2 HKDC1	7.47e-04	10	122	2	DOID:0050524 (implicated_via_orthology)
Disease	stromal cell-derived factor 1 alpha measurement	SPG7 CPS1 SORCS1	7.54e-04	43	122	3	EFO_0008293
Disease	obsolete_red blood cell distribution width	KMT2B CPS1 TEX9 PGC F8 ARL17A RAB9A RUVBL1 RNF146 SYNE2 PRKCE PLA2G6 EIF4G3 NMT1	1.37e-03	1347	122	14	EFO_0005192
Disease	autosomal dominant polycystic kidney disease (implicated_via_orthology)	LATS1 BICC1	1.49e-03	14	122	2	DOID:898 (implicated_via_orthology)
Disease	Hermansky-Pudlak syndrome (implicated_via_orthology)	CCZ1B CCZ1	1.49e-03	14	122	2	DOID:3753 (implicated_via_orthology)
Disease	melanoma	POGLUT3 SPG7 PARP1 PLA2G6	1.89e-03	126	122	4	EFO_0000756
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	MTOR BICC1	1.96e-03	16	122	2	DOID:0110861 (implicated_via_orthology)
Disease	thyroxine measurement, triiodothyronine measurement	RARS1 CCDC80	2.21e-03	17	122	2	EFO_0005130, EFO_0008392
Disease	hyperglycemia (implicated_via_orthology)	HK2 HKDC1	2.21e-03	17	122	2	DOID:4195 (implicated_via_orthology)
Disease	perinatal necrotizing enterocolitis (biomarker_via_orthology)	TLR6 PARP1	2.21e-03	17	122	2	DOID:8677 (biomarker_via_orthology)
Disease	Colorectal Carcinoma	COL3A1 ABCB5 IDH1 ARHGEF10L PARP1 AKAP9 GUCY1A2 EIF4G1 PRKCE	2.61e-03	702	122	9	C0009402
Disease	Intellectual Disability	NAA15 RARS1 CHD3 SLC1A2 PARP1 MTOR SYT1	2.63e-03	447	122	7	C3714756
Disease	congenital heart disease (implicated_via_orthology)	NAA15 KMT2B NAA16	2.96e-03	69	122	3	DOID:1682 (implicated_via_orthology)
Disease	susceptibility to mononucleosis measurement	DNAH2 MDH2 GGNBP1	2.96e-03	69	122	3	EFO_0008403
Disease	intellectual disability (implicated_via_orthology)	NAA15 GATAD2B NAA16	3.75e-03	75	122	3	DOID:1059 (implicated_via_orthology)
Disease	Paroxysmal atrial fibrillation	SYNE2 KIF3C KDM1B ARMH3	4.07e-03	156	122	4	C0235480
Disease	familial atrial fibrillation	SYNE2 KIF3C KDM1B ARMH3	4.07e-03	156	122	4	C3468561
Disease	Persistent atrial fibrillation	SYNE2 KIF3C KDM1B ARMH3	4.07e-03	156	122	4	C2585653

Protein segments in the cluster

Peptide	Gene	Start	Entry
EDKFKGSLSEGMKVE	PRPF4B	501	Q13523
MSLLCVGVKKAKFDG	UNC13A	1	Q9UPW8
NKLFKDDMEKLGLAI	AKAP9	2251	Q99996
LMKAAKSGTKDGLEK	ARHGEF10L	246	Q9HCE6
EGTMLKRLIEKKFGT	CATSPER1	716	Q8NEC5
TEKMKKGLSDFLGVI	BSDC1	71	Q9NW68
LIVTLKDGMLAEKGA	ABCB5	591	Q2M3G0
LDAKDKILKMNGETG	CFAP46	1576	Q8IYW2
GKLESLDGEELMKIK	ARMH3	61	Q5T2E6
MGNIFEKLFKSLLGK	ARL17A	1	Q8IVW1
KKLEAMLQAAAEGKG	BICC1	56	Q9H694
LKLKEQMAFVGFKGS	CEMIP	1316	Q8WUJ3
GKFGMVLLKKTLQVE	CCDC80	231	Q76M96
DADAKALRKAMKGLG	ANXA6	366	P08133
AKGLMDIFGKGKETE	RASSF8	136	Q8NHQ8
TLKSGFEDMFAKKEG	RANBP2	1531	P49792
MAGKSSLFKVILLGD	RAB9A	1	P51151
DEVKAMIEKLGGKLT	PARP1	406	P09874
MLGLDNAGKTTILKK	ARL2	21	P36404
DMTKGLVLGIYSKEK	LAP3	31	P28838
GEMALKDAKNKLEGL	KRT6C	416	P48668
KIEDFILHKMLGKGS	PRKCQ	376	Q04759
KSFGLPGDMVLLEKK	LAMA3	1541	Q16787
MENKTFLEKLKFGIG	NMT1	456	P30419
SKSGDIKKIIMGLDK	NCBP2	61	P52298
GFIGKMFKSLDLSLI	MGAT4B	301	Q9UQ53
GEMALKDAKNKLEGL	KRT6A	416	P02538
DKSMFVKIKTLGIGA	LATS1	701	O95835
TVGFLESELKKLLGM	GGNBP1	31	Q5YKI7
IKVLGKGSFGKVMLA	PRKCE	411	Q02156
KNLGIGKVSSFEEKM	MDH2	301	P40926
VKMAKEELLFGGKLS	HK2	311	P52789
AAKYKAMESKLLIGG	KIF3C	511	O14782
RFLVMASDLGKEKAK	EID3	91	Q8N140
TKMKEIAEAYLGGKV	HSPA2	126	P54652
KVFKGLDLLEKAAEM	IGBP1	41	P78318
GEMALKDAKNKLEGL	KRT6B	416	P04259
EVTRALMKILGKGKS	OR2M7	296	Q8NG81
MKGLTLNCLGKKEEA	NAA16	51	Q6N069
KDGQKLTLLKEMLAG	SLC25A22	96	Q9H936
MLTGKTLFKGKDYLD	MAPK13	216	O15264
KKLGALTAEEIALKM	KRR1	356	Q13601
VGKGEFTKDVGLKEM	F8	1171	P00451
AKKVKMGQLSLGLES	KMT2B	311	Q9UMN6
LKAANLEMFKGKGIE	GATAD2B	146	Q8WXI9
DMKAALGKLIGKVAV	OR1I1	296	O60431
AIAKIKMLGNIKFIG	EIF4G2	201	P78344
KMLGNIKFIGELGKL	EIF4G2	206	P78344
AKMLKSFLKAGGEVI	HPSE	276	Q9Y251
MKGLTLNCLGKKEEA	NAA15	51	Q9BXJ9
GLLDLKSMIEKVTGK	PLA2G5	21	P39877
KGKEEEILKALSGMC	POP1	256	Q99575
KSKVGDMLEKAAELL	PCID2	131	Q5JVF3
KIIRDKGTMLGKIEF	CPS1	171	P31327
EFMDKLGENLKIKLA	IDH1	396	O75874
KKMKAINSLGAGIIE	KDM1B	646	Q8NB78
KKEKEMVGALVSDGL	CHD3	1971	Q12873
KKGLEFKDGMNVLGL	SLC1A2	231	P43004
LLFLELSTGKVGMLK	FSTL4	761	Q6MZW2
TFLKAMEDGGVKLLK	CCZ1	151	P86791
VLSGIKMAALEEGLK	CHD1L	811	Q86WJ1
KMAALEEGLKKIFLA	CHD1L	816	Q86WJ1
NMRDKLFLTGKLGSK	GLB1L	456	Q6UWU2
TFLKAMEDGGVKLLK	CCZ1B	151	P86790
LGNIKFIGELFKLKM	EIF4G1	896	Q04637
FVKAGDKVKAGDSLM	MCCC1	661	Q96RQ3
MKFRAKITGKGCLEL	HUS1B	1	Q8NHY5
VKKALKLMGSNEGEF	COL3A1	1386	P02461
KEMKLLEQAGSLKGS	CRYL1	51	Q9Y2S2
ATEMLIFGKKLTAGE	ECI2	296	O75521
EKLGEKGKEIMTKYL	GRK5	96	P34947
MDLSGISKQLVKKGV	DNAH2	286	Q9P225
GNIKFIGELFKLKML	EIF4G3	891	O43432
LDKESGLLMFKGDKK	NYNRIN	1516	Q9P2P1
AEKGFDETLAKEKGM	MTOR	241	P42345
LGMIKAAGKKIYRLD	GUCY1A2	251	P33402
AFAEMKIKGLLDRKG	ALOX15B	191	O15296
EAKNLKKMDVGGLSD	SYT1	296	P21579
ILEAKNLKKMDVGGL	SYT2	291	Q8N9I0
LEAKNLKKMDVGGLS	SYT5	261	O00445
LGEGLKRSMDKLKEK	RARS1	466	P54136
MDVFKKGFSIAKEGV	SNCG	1	O76070
ASMELGKEAIAKGLL	SPHKAP	606	Q2M3C7
MDLSGVKKKSLLGVK	RNPS1	1	Q15287
GSLFGGMVLKKFLKE	TOP6BL	61	Q8N6T0
LMLIELKKKQEAGFA	SYNE2	2156	Q8WXH0
GVSFVDLMGIKALAK	SLC26A9	671	Q7LBE3
LKMAKAGLLFGGEKS	HKDC1	311	Q2TB90
GIKDLSKVKLMRFDD	LARS1	1106	Q9P2J5
KGKKNTEMLIAGFLY	RNF146	131	Q9NTX7
TKVDALKKMLLDQGG	MPV17	81	P39210
KVFFKAGLLGTLEEM	MYH4	766	Q9Y623
ELAKTVFGAKELGKM	PLA2G6	716	O60733
TIVDGKMGKGVSFKD	SPG7	296	Q9UQ90
ILLTVFKMKSKEGRG	OR5K4	221	A6NMS3
LGDFAVLLKAGMTVK	SLC39A6	641	Q13433
LDLVAKGDKMKIGCS	ADGRE1	451	Q14246
GKGTGEFIKALMKEI	CLCC1	316	Q96S66
DIGKEMYIIKEGKLA	CNGA2	486	Q16280
FQEKEKELGKAKLMG	POGLUT3	346	Q7Z4H8
LMGVEDTAKKGFFSK	VPS52	321	Q8N1B4
LKGMLKKFKEDLRGE	TRIM7	321	Q9C029
FKSIRETMKEKGLLG	PGC	26	P20142
KFMDKKLSLKLNGGR	SNRPG	11	P62308
KYDLKKNILGDVMSG	SLC26A2	101	P50443
MKGLNGKVSDLEKAA	SPTAN1	1951	Q13813
MTGLKKEKLEDLGLK	PIEZO2	766	Q9H5I5
GKTCLMKAVLNLKDG	TRPV2	116	Q9Y5S1
RKSLFGKKNMLVGEV	TTC41P	976	Q6P2S7
DLKMFLLSKGASKEV	MTERF1	106	Q99551
LMSLKRKEKGVIFGS	ARHGAP19	101	Q14CB8
MKLKDSLFDLDGPKV	PHF23	131	Q9BUL5
IKSKKMAGRAVLLAG	RUVBL1	56	Q9Y265
KNGLKDLFKVGLMTK	TLR6	386	Q9Y2C9
LALKGGKRTIMKLEA	MYH16	966	Q9H6N6
LKQVFGKGLIKAAMT	TRPM1	116	Q7Z4N2
DVLKDDKMGLKFLGT	WFIKKN1	461	Q96NZ8
DKMGLKFLGTKYLEV	WFIKKN1	466	Q96NZ8
FVGEKVDEEGLKKLM	S100A2	46	P29034
LLKKLMSGVENSGKV	TRIP4	226	Q15650
GAELALLLGKDMFSK	WDR27	586	A2RRH5
EVAGIKGMFLANKKI	SORCS1	471	Q8WY21
CLKLMLKKSGLQGDA	USP40	871	Q9NVE5
GELMIGFKKQLKLID	TEX9	346	Q8N6V9
LQVMFDALKEGVKKG	UNC45A	261	Q9H3U1
KEMRFLKGDTTDLLK	ZW10	376	O43264
LLAVAVKDKSMEGLK	PSMG3	96	Q9BT73
DEVLKDEKMGLKFLG	WFIKKN2	486	Q8TEU8