Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesspositive regulation of Arp2/3 complex-mediated actin nucleation

CYFIP1 WASF1 WASF2

3.21e-078383GO:2000601
GeneOntologyBiologicalProcesspositive regulation of actin nucleation

CYFIP1 WASF1 WASF2

2.07e-0614383GO:0051127
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

GPC1 FUZ MTMR4 CYFIP1 ZFYVE9 WASF1 SMAD7

8.91e-06412387GO:0090287
GeneOntologyBiologicalProcessregulation of Arp2/3 complex-mediated actin nucleation

CYFIP1 WASF1 WASF2

2.50e-0531383GO:0034315
GeneOntologyBiologicalProcessregulation of alkaline phosphatase activity

PPARGC1B HPN

4.93e-056382GO:0010692
GeneOntologyBiologicalProcessregulation of actin nucleation

CYFIP1 WASF1 WASF2

5.86e-0541383GO:0051125
GeneOntologyBiologicalProcessArp2/3 complex-mediated actin nucleation

CYFIP1 WASF1 WASF2

8.85e-0547383GO:0034314
GeneOntologyBiologicalProcesspositive regulation of neurotrophin TRK receptor signaling pathway

CYFIP1 WASF1

9.19e-058382GO:0051388
GeneOntologyBiologicalProcessnegative regulation of epithelial to mesenchymal transition

FUZ HPN SMAD7

1.49e-0456383GO:0010719
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

GPC1 FUZ MTMR4 SMAD7

1.64e-04150384GO:0090288
GeneOntologyBiologicalProcessRac protein signal transduction

CYFIP1 WASF1 WASF2

1.84e-0460383GO:0016601
GeneOntologyBiologicalProcessactin nucleation

CYFIP1 WASF1 WASF2

2.33e-0465383GO:0045010
GeneOntologyBiologicalProcessestablishment of T cell polarity

TRAF3IP2 SCRIB

3.42e-0415382GO:0001768
GeneOntologyBiologicalProcessestablishment of lymphocyte polarity

TRAF3IP2 SCRIB

3.90e-0416382GO:0001767
GeneOntologyBiologicalProcessregulation of neurotrophin TRK receptor signaling pathway

CYFIP1 WASF1

4.42e-0417382GO:0051386
GeneOntologyBiologicalProcesslamellipodium morphogenesis

WASF1 WASF2

4.96e-0418382GO:0072673
GeneOntologyBiologicalProcesspositive regulation of cytoskeleton organization

CYFIP1 STIL WASF1 WASF2

5.37e-04205384GO:0051495
GeneOntologyCellularComponentSCAR complex

CYFIP1 WASF1 WASF2

1.21e-0612383GO:0031209
DomainSCAR/WAVE_fam

WASF1 WASF2

1.14e-053372IPR028288
DomainWH2

WASF1 WASF2

3.42e-0414372SM00246
DomainWH2

WASF1 WASF2

4.50e-0416372PF02205
DomainLRR

ISLR SCRIB LGR5 CIITA

6.51e-04201374PS51450
DomainWH2_dom

WASF1 WASF2

7.83e-0421372IPR003124
DomainLRR_1

ISLR SCRIB LGR5 CIITA

8.97e-04219374PF00560
DomainWH2

WASF1 WASF2

1.03e-0324372PS51082
DomainFYVE

MTMR4 ZFYVE9

1.50e-0329372PF01363
DomainFYVE

MTMR4 ZFYVE9

1.50e-0329372SM00064
DomainLeu-rich_rpt

ISLR SCRIB LGR5 CIITA

1.96e-03271374IPR001611
DomainZnf_FYVE-rel

MTMR4 ZFYVE9

2.06e-0334372IPR017455
DomainZnf_FYVE

MTMR4 ZFYVE9

2.57e-0338372IPR000306
DomainZF_FYVE

MTMR4 ZFYVE9

2.84e-0340372PS50178
Domain-

ISLR SCRIB LGR5 CIITA

3.62e-033213743.80.10.10
DomainL_dom-like

ISLR SCRIB LGR5 CIITA

3.91e-03328374IPR032675
DomainLRR_8

ISLR SCRIB LGR5

4.66e-03171373PF13855
DomainLeu-rich_rpt_typical-subtyp

ISLR SCRIB LGR5

5.13e-03177373IPR003591
DomainLRR_TYP

ISLR SCRIB LGR5

5.13e-03177373SM00369
DomainHEAT_REPEAT

SCYL2 COPG2

8.47e-0370372PS50077
PathwayKEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPE_TO_RAC_SIGNALING_PATHWAY

CYFIP1 WASF1 WASF2

8.72e-0620293M47737
PathwayKEGG_MEDICUS_REFERENCE_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY

CYFIP1 WASF1 WASF2

1.75e-0525293M47716
PathwayREACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING

MTMR4 ZFYVE9 SMAD7

1.97e-0526293M628
PathwayKEGG_MEDICUS_PATHOGEN_SHIGELLA_IPGD_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY

CYFIP1 WASF1 WASF2

2.76e-0529293M47717
PathwayKEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY

CYFIP1 WASF1 WASF2

3.06e-0530293M47738
PathwayREACTOME_RHO_GTPASES_ACTIVATE_WASPS_AND_WAVES

CYFIP1 WASF1 WASF2

4.49e-0534293MM15265
PathwayREACTOME_RHO_GTPASES_ACTIVATE_WASPS_AND_WAVES

CYFIP1 WASF1 WASF2

5.34e-0536293M27549
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

MTMR4 ZFYVE9 SMAD7

6.29e-0538293MM14874
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

MTMR4 ZFYVE9 SMAD7

1.19e-0447293M646
PathwayBIOCARTA_ACTINY_PATHWAY

WASF1 WASF2

1.82e-0410292MM1528
PathwayBIOCARTA_ACTINY_PATHWAY

WASF1 WASF2

2.66e-0412292M7825
PathwayREACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING

MTMR4 SMAD7

4.82e-0416292MM14873
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

MTMR4 ZFYVE9 SMAD7

5.17e-0477293MM14670
PathwayBIOCARTA_TGFB_PATHWAY

ZFYVE9 SMAD7

6.84e-0419292M18933
PathwayREACTOME_RAC3_GTPASE_CYCLE

CYFIP1 WASF1 WASF2

8.97e-0493293MM15609
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

MTMR4 ZFYVE9 SMAD7

9.25e-0494293M1041
PathwayREACTOME_RAC3_GTPASE_CYCLE

CYFIP1 WASF1 WASF2

9.25e-0494293M41818
PathwayREACTOME_SIGNALING_BY_VEGF

CYFIP1 WASF1 WASF2

1.21e-03103293MM14752
PathwayREACTOME_SIGNALING_BY_VEGF

CYFIP1 WASF1 WASF2

1.31e-03106293M27077
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

CYFIP1 WASF1 WASF2

1.61e-03114293MM14814
PathwayREACTOME_PARASITE_INFECTION

CYFIP1 WASF1 WASF2

1.70e-03116293M29843
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

MTMR4 ZFYVE9 SMAD7

1.78e-03118293MM15588
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

CYFIP1 WASF1 WASF2

3.08e-03143293M27107
Pubmed

Structure and control of the actin regulatory WAVE complex.

CYFIP1 WASF1 WASF2

6.71e-08838321107423
Pubmed

Neurodevelopmental disorder-associated CYFIP2 regulates membraneless organelles and eIF2α phosphorylation via protein interactors and actin cytoskeleton.

CYFIP1 WASF1 WASF2

1.01e-07938338981622
Pubmed

Abi1 is essential for the formation and activation of a WAVE2 signalling complex.

CYFIP1 WASF1 WASF2

1.44e-071038315048123
Pubmed

WAVE1 and WAVE2 have distinct and overlapping roles in controlling actin assembly at the leading edge.

WASF1 WASF2

1.16e-06238232697617
Pubmed

Phosphorylation of WAVE2 by MAP kinases regulates persistent cell migration and polarity.

WASF1 WASF2

1.16e-06238218032787
Pubmed

Regulation of WAVE1 expression in macrophages at multiple levels.

WASF1 WASF2

1.16e-06238218765479
Pubmed

Smad7 Knockdown Restores Aryl Hydrocarbon Receptor-mediated Protective Signals in the Gut.

AHR SMAD7

1.16e-06238226818761
Pubmed

Loss of aryl hydrocarbon receptor suppresses the response of colonic epithelial cells to IL22 signaling by upregulating SOCS3.

AHR LGR5

1.16e-06238234755534
Pubmed

Genomic organization and expression profile of the human and mouse WAVE gene family.

WASF1 WASF2

3.48e-06338212856283
Pubmed

The Environmental Sensor AHR Protects from Inflammatory Damage by Maintaining Intestinal Stem Cell Homeostasis and Barrier Integrity.

AHR LGR5

3.48e-06338230119997
Pubmed

SMURF2 and SMAD7 induce SARA degradation via the proteasome.

ZFYVE9 SMAD7

3.48e-06338232283253
Pubmed

SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development.

WASF1 WASF2

3.48e-0633829732292
Pubmed

WAVE/Scars in platelets.

WASF1 WASF2

3.48e-06338215280206
Pubmed

Characterization of the WAVE1 knock-out mouse: implications for CNS development.

WASF1 WASF2

3.48e-06338212716942
Pubmed

Expression and subcellular localization of WAVE isoforms in the megakaryocyte/platelet lineage.

WASF1 WASF2

3.48e-06338215670045
Pubmed

Neutrophils establish rapid and robust WAVE complex polarity in an actin-dependent fashion.

WASF1 WASF2

6.96e-06438219200726
Pubmed

mDia1 and WAVE2 proteins interact directly with IRSp53 in filopodia and are involved in filopodium formation.

WASF1 WASF2

6.96e-06438222179776
Pubmed

The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery.

WASF1 WASF2

6.96e-06438217664349
Pubmed

Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation.

CYFIP1 WASF2

6.96e-06438214765121
Pubmed

Loss of aryl hydrocarbon receptor potentiates FoxM1 signaling to enhance self-renewal of colonic stem and progenitor cells.

AHR LGR5

6.96e-06438232915464
Pubmed

Retrolinkin recruits the WAVE1 protein complex to facilitate BDNF-induced TrkB endocytosis and dendrite outgrowth.

CYFIP1 WASF1

6.96e-06438227605705
Pubmed

Interaction between Wiskott-Aldrich Syndrome protein (WASP) and the Fyn protein-tyrosine kinase.

WASF1 WASF2

6.96e-06438210532312
Pubmed

WAVE2 is required for directed cell migration and cardiovascular development.

WASF1 WASF2

1.16e-05538212879075
Pubmed

IL-17A-Induced PLET1 Expression Contributes to Tissue Repair and Colon Tumorigenesis.

TRAF3IP2 LGR5

1.16e-05538229070673
Pubmed

Wiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cells.

WASF1 WASF2

1.16e-0553829307968
Pubmed

Local F-actin network links synapse formation and axon branching.

CYFIP1 WASF1

1.16e-05538224439377
Pubmed

FBP11 regulates nuclear localization of N-WASP and inhibits N-WASP-dependent microspike formation.

WASF1 WASF2

1.16e-05538214697212
Pubmed

HIV-1 Nef drives macrophages into hiding.

WASF1 WASF2

1.74e-05638225745180
Pubmed

HIV-1 reprograms the migration of macrophages.

WASF1 WASF2

1.74e-05638225527710
Pubmed

Scar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffold.

WASF1 WASF2

1.74e-05638210970852
Pubmed

PSTPIP 2, a second tyrosine phosphorylated, cytoskeletal-associated protein that binds a PEST-type protein-tyrosine phosphatase.

WASF1 WASF2

1.74e-0563829804817
Pubmed

Interleukin-22 protects intestinal stem cells against genotoxic stress.

AHR LGR5

1.74e-05638230700914
Pubmed

Free Brick1 is a trimeric precursor in the assembly of a functional wave complex.

CYFIP1 WASF2

2.43e-05738218560548
Pubmed

Smaller Body Size, Early Postnatal Lethality, and Cortical Extracellular Matrix-Related Gene Expression Changes of Cyfip2-Null Embryonic Mice.

CYFIP1 WASF1

2.43e-05738230687000
Pubmed

Quick validation of genetic quality for conditional alleles in mice.

ISLR SMAD7

2.43e-05738233540482
Pubmed

Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex.

WASF1 WASF2

2.43e-0573829889097
Pubmed

Genome-wide association study indicates variants associated with insulin signaling and inflammation mediate lipoprotein responses to fenofibrate.

PPARGC1B PDE10A

2.43e-05738222890011
Pubmed

Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex.

WASF1 WASF2

3.24e-05838210381382
Pubmed

IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling.

WASF1 WASF2

3.24e-05838211130076
Pubmed

A systematic evaluation of protein kinase A-A-kinase anchoring protein interaction motifs.

WASF1 WASF2

3.24e-05838225097019
Pubmed

Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis.

ATF6 LGR5

3.24e-05838224519940
Pubmed

Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex.

WASF1 WASF2

3.24e-05838211146629
Pubmed

Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck.

WASF1 WASF2

3.24e-05838212181570
Pubmed

Confirmed rare copy number variants implicate novel genes in schizophrenia.

CYFIP1 PDE10A

4.16e-05938220298200
Pubmed

IL-17R-EGFR axis links wound healing to tumorigenesis in Lrig1+ stem cells.

TRAF3IP2 LGR5

4.16e-05938230578323
Pubmed

The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis.

SCRIB LGR5

5.20e-051038226376988
Pubmed

NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylation.

WASF1 WASF2

5.20e-051038217101133
Pubmed

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.

CYFIP1 WASF1 WASF2

5.49e-056738321875946
Pubmed

The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex.

ANKRD31 CYFIP1 EFEMP1

6.81e-057238333726789
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ADGRA1 CYFIP1 SCRIB WASF1 N4BP2 WASF2 NAT10

7.28e-0596338728671696
Pubmed

Topologically associating domain boundaries are required for normal genome function.

AHR SMAD7

7.62e-051238237081156
Pubmed

WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelination.

WASF1 WASF2

9.00e-051338216723544
Pubmed

Stability of the cancer target DDIAS is regulated by the CHIP/HSP70 pathway in lung cancer cells.

EFEMP1 PLSCR1

9.00e-051338228079882
Pubmed

Immune tolerance. Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4⁺ T cells.

AHR CIITA

9.00e-051338225908663
Pubmed

Rac1 signaling is critical to cardiomyocyte polarity and embryonic heart development.

SCRIB WASF2

1.05e-041438225315346
Pubmed

Axis specification and morphogenesis in the mouse embryo require Nap1, a regulator of WAVE-mediated actin branching.

CYFIP1 WASF1

1.56e-041738216831833
Pubmed

In mouse brain profilin I and profilin II associate with regulators of the endocytic pathway and actin assembly.

CYFIP1 WASF1

1.76e-04183829463375
Pubmed

NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons.

CYFIP1 WASF1

2.65e-042238221946561
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

SCYL2 COPG2 SCRIB PLSCR1 WASF2

3.58e-0456538525468996
Pubmed

Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination.

SCYL2 PLSCR1

4.01e-042738230442762
Pubmed

Functional proteomics mapping of a human signaling pathway.

SCYL2 MTMR4 ZFYVE9 SMAD7 TMEM139

4.40e-0459138515231748
Pubmed

Loss of Mptx2 alters bacteria composition and intestinal homeostasis potentially by impairing autophagy.

ATF6 LGR5

4.96e-043038238218976
Pubmed

Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain.

CYFIP1 WASF1 WASF2

5.17e-0414338332560809
Pubmed

GRAMD4 inhibits tumour metastasis by recruiting the E3 ligase ITCH to target TAK1 for degradation in hepatocellular carcinoma.

COPG2 NAT10

6.01e-043338234841685
Pubmed

The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters.

COPG2 NAT10

6.01e-043338226296893
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

SCYL2 COPG2 CYFIP1 SCRIB NAT10

6.22e-0463838533239621
Pubmed

α-catenin interaction with YAP/FoxM1/TEAD-induced CEP55 supports liver cancer cell migration.

CYFIP1 SCRIB

6.76e-043538237381005
Pubmed

Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.

SCYL2 STIL N4BP2

8.39e-0416938331462741
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

COPG2 MTMR4 SCRIB ZFYVE9 WASF1 NAT10

8.97e-04104938627880917
Pubmed

Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1.

SCRIB SPIDR

9.28e-04413828590280
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

SCYL2 COPG2 CYFIP1 SCRIB WASF2

9.92e-0470838539231216
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

ISLR CYFIP1 EFEMP1 PLSCR1 HPN WASF2

9.94e-04107038623533145
InteractionZFPL1 interactions

SCYL2 COPG2 MTMR4 SCRIB HPN WASF2 TMEM139

1.22e-05448367int:ZFPL1
Cytoband3q23

PXYLP1 PLSCR1

6.17e-04443823q23
Cytoband5q32

PPARGC1B SH3RF2

9.29e-04543825q32
CytobandEnsembl 112 genes in cytogenetic band chr5q32

PPARGC1B SH3RF2

2.02e-0380382chr5q32
Cytoband6q21

TRAF3IP2 WASF1

2.90e-03963826q21
CytobandEnsembl 112 genes in cytogenetic band chr6q21

TRAF3IP2 WASF1

4.55e-03121382chr6q21
GeneFamilyWiskott-Aldrich Syndrome protein family

WASF1 WASF2

2.36e-041626214
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

MTMR4 ZFYVE9

9.01e-043126281
CoexpressionGOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_DN

GPC1 TRAF3IP2 ATF6 CYFIP1 PLSCR1

1.01e-05200385M3039
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_D_DN

GPC1 PXYLP1

7.32e-059382MM482
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_D_DN

GPC1 PXYLP1

9.14e-0510382M527
CoexpressionGSE9988_LPS_VS_LOW_LPS_MONOCYTE_DN

PPARGC1B ISLR STIL LGR5

1.50e-04186384M5855
CoexpressionGSE29618_PRE_VS_DAY7_FLU_VACCINE_BCELL_UP

GPC1 ISLR STIL LGR5

1.83e-04196384M4972
CoexpressionGSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_DN

AHR PXYLP1 MTMR4 STIL

1.91e-04198384M3352
CoexpressionGSE43863_LY6C_INT_CXCR5POS_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP

EFEMP1 WASF1 WASF2 SMAD7

1.94e-04199384M9754
CoexpressionGSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_STIM_DN

AHR KCNK6 CYFIP1 PLSCR1

1.98e-04200384M7958
CoexpressionGSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_KO_MACROPHAGE_UP

GPC1 CYFIP1 STIL HPN

1.98e-04200384M9033
CoexpressionGSE19772_CTRL_VS_HCMV_INF_MONOCYTES_UP

AHR ATF6 CYFIP1 PLSCR1

1.98e-04200384M7282
CoexpressionGSE23568_CTRL_TRANSDUCED_VS_WT_CD8_TCELL_UP

ATF6 CYFIP1 CIITA PLSCR1

1.98e-04200384M8522
CoexpressionGSE40068_CXCR5NEG_BCL6NEG_CD4_TCELL_VS_CXCR5POS_BCL6NEG_TFH_DN

GPC1 ATF6 PLSCR1 NAT10

1.98e-04200384M9263
CoexpressionGSE17721_POLYIC_VS_PAM3CSK4_2H_BMDC_UP

TRAF3IP2 ATF6 PPARGC1B SCRIB

1.98e-04200384M3830
CoexpressionGSE9878_CTRL_VS_EBF_TRANSDUCED_PAX5_KO_PRO_BCELL_UP

ISLR PLSCR1 HPN SMAD7

1.98e-04200384M6988
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

R3HDM2 SPIDR STIL ZFYVE9 WASF1 PLSCR1 SMAD7

2.01e-04856387M4500
ToppCellMS-CD4-CD8_2|MS / Condition, Cell_class and T cell subcluster

PXYLP1 SCRIB CCDC24 PRR29

7.81e-0614938408fb6be5599c5988890c851ce5ac6781c319948e
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

KCNK6 CYFIP1 CIITA PLSCR1

9.85e-06158384216b3f482daa2d0d7fcaf5a8559e3ccbdb8e110d
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KCNK6 CYFIP1 CIITA PLSCR1

9.85e-061583849712bb8b1bacb8a38c99a22bc2babec5d5160e2a
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COPG2 PXYLP1 N4BP2 NAT10

1.31e-051703843ad9f950b87ee98f025ab9b4a8ed551e6a9b4764
ToppCell11.5-Airway-Epithelial-Basal_cell|Airway / Age, Tissue, Lineage and Cell class

EFEMP1 LGR5 HPN TMEM139

1.38e-051723849d4d92e2d16dfc8a394f2641653bb97de20a2530
ToppCell10x5'-bone_marrow-Myeloid_Dendritic-DC2|bone_marrow / Manually curated celltypes from each tissue

AHR CYFIP1 CIITA PLSCR1

1.38e-0517238464928cea7e5b60e4bc4af016454b0173ebcc07c7
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic-DC2|bone_marrow / Manually curated celltypes from each tissue

AHR KCNK6 CIITA PLSCR1

1.75e-05183384f482e4fe011fa450a475034b1e25587233855bdb
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AHR ANKRD31 KCNK6 CIITA

1.79e-05184384a45980306c4e697a2703bed72a7b48fb23d942f4
ToppCellmild-Myeloid-mDC|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

AHR KCNK6 CYFIP1 CIITA

1.79e-051843848b37c00d59d9992d3b43268991da7bb94646c70e
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AHR ANKRD31 KCNK6 CIITA

1.79e-051843841c56378b3888c46258d446b47de4d6282fe74b0d
ToppCellCOVID_non-vent-Myeloid-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

AHR KCNK6 CYFIP1 CIITA

1.91e-05187384936aaca144b79a809617cbe3058bf434a4b3d46a
ToppCellCOVID_non-vent-Myeloid-Dendritic-cDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

AHR KCNK6 CYFIP1 CIITA

1.91e-0518738455fe4e8b4f301876716c1af15c34d42164f2358e
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC24 LGR5 SH3RF2 HPN

2.08e-05191384a8d77095ba20b47fc70ba04f80759fbce873253d
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNK6 ISLR CYFIP1 EFEMP1

2.16e-0519338406b65110db974f4ef90d3511ff34428976a52c9c
ToppCellfacs-Brain_Non-Myeloid-Striatum|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE10A WASF1 EGR4 SH3RF2

2.16e-05193384d8ccfb780a75bdf9141f41fb29a076958601ebb4
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNK6 ISLR CYFIP1 EFEMP1

2.16e-051933849c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCellfacs-Brain_Myeloid-Hippocampus-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNK6 ISLR CYFIP1 EFEMP1

2.16e-05193384a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNK6 ISLR CYFIP1 EFEMP1

2.16e-05193384b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCell356C-Myeloid-Dendritic-cDC2|356C / Donor, Lineage, Cell class and subclass (all cells)

AHR KCNK6 CIITA PLSCR1

2.25e-051953844c9a2167d8cfe40dfd609c303ada5b5ef800bd8f
ToppCellhealthy_donor-Myeloid-Dendritic-cDC|healthy_donor / Disease condition, Lineage, Cell class and subclass

AHR KCNK6 CYFIP1 CIITA

2.30e-05196384aac79fc45cab4a16e2fa02652ece0999591261a5
ToppCell356C-Myeloid-Dendritic|356C / Donor, Lineage, Cell class and subclass (all cells)

AHR KCNK6 CIITA PLSCR1

2.30e-051963841425eb35bd170d434c47390773e5c74c30c2f592
ToppCellhealthy_donor-Myeloid-Dendritic|healthy_donor / Disease condition, Lineage, Cell class and subclass

AHR KCNK6 CYFIP1 CIITA

2.30e-05196384ea590b8ea3d13ff93cb5863a44936b0cfdf3b868
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-cDC2-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AHR KCNK6 CIITA PLSCR1

2.34e-051973844f7c10a636646dfc82a84026c1b5a36603367abe
ToppCellCOVID-19_Moderate-cDC|COVID-19_Moderate / disease group, cell group and cell class

AHR KCNK6 CYFIP1 CIITA

2.34e-05197384ff45a212434a1b128e1a217c6abdec6380938da9
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-cDC2|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AHR KCNK6 CIITA PLSCR1

2.39e-05198384da36c1bb62fdd1da7aca9c5115432a87fb48adb0
ToppCellHealthy-cDC|Healthy / disease group, cell group and cell class

AHR KCNK6 CIITA PLSCR1

2.39e-051983844cf874333b9fd6cd22ee647cd12c032fc6d05740
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AHR KCNK6 CYFIP1 CIITA

2.39e-05198384c1fe38594bd6292fcc60bdbb563376b454731d00
ToppCellCOVID-19_Severe-cDC|World / disease group, cell group and cell class

KCNK6 CYFIP1 CIITA PLSCR1

2.39e-05198384c452334249f047265ae89dcabe7de446d968cae6
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AHR KCNK6 CYFIP1 CIITA

2.39e-05198384bfc15de70a7577a2860b53e1e6826a7b5ad23040
ToppCellBronchial-10x5prime-Immune_Myeloid-Dendritic_cell-DC_2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AHR KCNK6 CIITA PLSCR1

2.44e-05199384fdd8c4c04837341e17a4772a2adcdf2f187c56b1
ToppCellcontrol-HLA-DR+_CD83+_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

AHR CYFIP1 CIITA PLSCR1

2.44e-05199384f1b370d2869ad29c9d8ff41fdcc486fffa781ee2
ToppCellcontrol-cDC|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

AHR KCNK6 CYFIP1 CIITA

2.48e-052003844a6d17a4225be38537d3dd8a39512051f597f4e0
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a|Striatum / BrainAtlas - Mouse McCarroll V32

PDE10A EGR4 SH3RF2

1.10e-04109383e8e0f2c5f8c9e45f2b4d173569c94275eedfe432
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AHR PLSCR1 HPN

2.44e-041433834c5a5db46beb8f2f3c40e8ed95911fbfea61bae0
ToppCellfacs-Brain_Myeloid-Cerebellum_-18m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHR CIITA PLSCR1

2.87e-041513833105b8c0c401faa92e1ab8223d435b21ed45c5b7
ToppCellHippocampus-Macroglia-CSF_related|Hippocampus / BrainAtlas - Mouse McCarroll V32

SH3RF2 PRR29 TMEM139

2.92e-04152383c2b6cc41546cbd46b9ea5d28a7c66f6330a27df2
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ISLR EFEMP1 SH3RF2

2.98e-04153383151c469b26f9adf04dd6f117f03bef760cc3d45d
ToppCellfacs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC1 AHR CIITA

2.98e-041533830ef7c45cdd854c79e527006034029767f8e108b2
ToppCellnormal_Lung-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

KCNK6 CIITA WASF1

3.04e-04154383835ef49d314ecbcbfd8d1041ba202a5eedcda0bd
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-liver_dendritic_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KCNK6 CIITA PLSCR1

3.16e-04156383411c170a7dd65269ae442b8069caf5231bddb116
ToppCellGlobus_pallidus-Neuronal-Excitatory|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PDE10A EGR4 SH3RF2

3.40e-04160383f843287ed57d2d5a3b3f6dfb03b6934e330e6645
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

PDE10A EGR4 SH3RF2

3.46e-04161383ebcd5066e82b7760b9da6adc02d11258d1309dab
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mast-Mast|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AHR ANKRD31 SMAD7

3.52e-0416238330508c4007faa38b76246e3c6d7b3fde4492cc85
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mast|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AHR ANKRD31 SMAD7

3.52e-0416238333b73c6727b5c5ada2dddf304f56d84397725ca8
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mast-Mast-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AHR ANKRD31 SMAD7

3.52e-0416238344ef0932ee38964ff11edc2aa14698d9db3b2b6b
ToppCell343B-Fibroblasts-Fibroblast-D-|343B / Donor, Lineage, Cell class and subclass (all cells)

ISLR WASF1 EGR4

3.59e-041633838d2b2119c6b3d5b677da6f377fd85146590e1246
ToppCell343B-Fibroblasts-Fibroblast-D|343B / Donor, Lineage, Cell class and subclass (all cells)

ISLR WASF1 EGR4

3.59e-04163383acfb2ece6202479e615d54fd3ecb8b4a571b5a18
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KCNK6 STIL CIITA

3.65e-0416438343045879505774ac0d9b7f760557955564f06d00
ToppCellnormal_Lymph_Node-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

KCNK6 CIITA SH3RF2

3.78e-041663836210a136efb99d70c2026b6454363f1bd2723558
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE10A CIITA SH3RF2

3.92e-04168383b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AHR COPG2 CIITA

3.92e-04168383d60f7cd8269f373827f49c7785002cb38e4570a9
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ISLR EFEMP1 PLSCR1

3.92e-041683839930bd63b60c03f0152838a79eef77da1c2dd8e5
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE10A CIITA SH3RF2

3.92e-04168383b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCellP28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GPC1 NAT10 TMEM139

3.92e-041683838c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCellAT1-AT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

EFEMP1 SH3RF2 TMEM139

3.99e-04169383815474855a70498a74e52f6583113c63b7267a0c
ToppCell10x5'v1-week_17-19-Myeloid_DC-DC-DC1|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

AHR KCNK6 SH3RF2

3.99e-04169383488ba50631a64cb9e0d69219491c66ac824c9e7d
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AHR COPG2 CIITA

3.99e-04169383ccd98f9005aa0a88bd49f153be4e7200cc3dd0ac
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCYL2 GPC1 PXYLP1

4.13e-04171383913bae728b5e653771a27c79a309eb023699f1d0
ToppCellCOVID-19_Convalescent-cDC-|COVID-19_Convalescent / Disease condition and Cell class

KCNK6 CIITA SH3RF2

4.13e-04171383fb5fae8b3adafcbb7c5618d887966b418355ed4d
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCYL2 GPC1 PXYLP1

4.13e-04171383f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCellCOVID-19_Convalescent-cDC|COVID-19_Convalescent / Disease condition and Cell class

KCNK6 CIITA SH3RF2

4.13e-041713839ccaa9f1629818b0f63a5d930ee78c01e04cd98d
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

EFEMP1 SH3RF2 TMEM139

4.20e-041723830be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGRA1 CCDC24 TMEM139

4.20e-0417238373e9b29b1c6b8b016b495a0d20336d0c0761e5e2
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

COPG2 KCNK6 STIL

4.27e-0417338320889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell10x5'-Lung-Myeloid_Dendritic-Cycling_Dendritic|Lung / Manually curated celltypes from each tissue

STIL WASF1 SH3RF2

4.27e-0417338362e0c18cfed9645e34a9d7029c94a8554f773714
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

COPG2 KCNK6 STIL

4.27e-0417338346e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-mature_enterocytic-Paneth|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC24 LGR5 HPN

4.34e-04174383b4483d7d9f22f09ed7fa0b72305434a47ccaade0
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ISLR EFEMP1 PLSCR1

4.34e-041743832891ab2fd05eb4bbd239d1a2865f21ef7f2df39e
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ISLR EFEMP1 PLSCR1

4.34e-04174383eade55f86ef1f7a5355ad65cec3aa6bfc5d3c62d
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LGR5 SH3RF2 HPN

4.41e-041753836759d200a133034756de9cdf2d5daceca927aac9
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-cDC2-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AHR CIITA PLSCR1

4.49e-04176383a31d7532f8c055d4e62bbaa78d819f2495bfee00
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-DC2|lymph-node_spleen / Manually curated celltypes from each tissue

KCNK6 CIITA PLSCR1

4.49e-0417638372a3bbab0540ae3e3c94b9573cdb9298a024dbc4
ToppCellBAL-Severe-cDC_3|Severe / Compartment, Disease Groups and Clusters

AHR ANKRD31 CIITA

4.56e-04177383939487a05311b66edfc3f44a7955fbf25266d6bf
ToppCellEndothelial-Endothelial-C|Endothelial / shred on cell class and cell subclass (v4)

EFEMP1 PLSCR1 SMAD7

4.56e-04177383b5b9278dfd76b1aacd88e5fe86e91a2c9b565f87
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STIL LGR5 HPN

4.72e-041793836405010e8136a4d9bab356f628e36e3194911112
ToppCellmild_COVID-19_(asymptomatic)-cDC|World / disease group, cell group and cell class (v2)

KCNK6 CIITA PLSCR1

4.79e-0418038368d1c867734fb2977b01ac686b20bf602f9a6b72
ToppCellFLU-Healthy-0|FLU / Virus stimulation, Condition and Cluster

FUZ CYFIP1 TMEM139

5.03e-04183383058604ddb06b3bef131183d86b83b422dae8f6cb
ToppCellIPF-Epithelial-ATI|World / Disease state, Lineage and Cell class

EFEMP1 SH3RF2 TMEM139

5.03e-0418338331fef35ecf30162662f24d335d8f0cceacc07039
ToppCellCOVID-19-APC-like-Dendritic_cells|COVID-19 / group, cell type (main and fine annotations)

AHR KCNK6 CIITA

5.03e-04183383703364836b42aa6ac6c68b42b700ac23c4a1afc7
ToppCellDendritic_Cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

KCNK6 CIITA PLSCR1

5.03e-04183383dd09e39e8ca282ff0f470e0652d519e190badd0b
ToppCellIPF-Lymphoid-ILC_B|Lymphoid / Disease state, Lineage and Cell class

AHR ADGRA1 HPN

5.03e-041833839b507547e6adf78e46e7f542cd9958224ec5826a
ToppCellCOVID-19-APC-like|COVID-19 / group, cell type (main and fine annotations)

AHR KCNK6 CIITA

5.03e-04183383b8f5afaf9ff1b2b1bc60be58654d1b23859dafa9
ToppCellFLU-Healthy-0|Healthy / Virus stimulation, Condition and Cluster

FUZ CYFIP1 TMEM139

5.03e-041833837a6f18246c39864479e114f698581f667fa9c600
ToppCellIPF-Epithelial-ATI|IPF / Disease state, Lineage and Cell class

EFEMP1 SH3RF2 TMEM139

5.03e-04183383c0a3541c45bd0c587603521f392f42dd86c3c35b
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KCNK6 CIITA SH3RF2

5.11e-04184383315bb14e848d8e8e4533122047df6f9b89b89d99
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

GPC1 PXYLP1 WASF1

5.11e-04184383ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCellFrontal_cortex-Neuronal-Excitatory|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ATF6 R3HDM2 EGR4

5.11e-041843836e17c8151d6dc543de16d804db956c63c3fda414
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT1-AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EFEMP1 SH3RF2 HPN

5.19e-041853833bef59cc0aa939d2a7e52f0f6c61bc00528fe50b
ToppCellControl-Epithelial-ATI|World / Disease state, Lineage and Cell class

EFEMP1 SH3RF2 TMEM139

5.19e-041853830563d5042bb96ecce8446fbf26d05ef7a45e23c5
ToppCelldroplet-Fat-Scat-21m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ISLR EFEMP1 WASF1

5.19e-0418538301bbe1e09f9ccae837a03ea2cdd168fa10800942
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

R3HDM2 LGR5 HPN

5.19e-041853831d874608aa2062024323512f68889219471b2f00
ToppCelldroplet-Marrow-nan-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC1 PXYLP1 PLSCR1

5.19e-041853833dcafbd02b65a2befbb6e6288cb2591e721cddb6
ToppCelldroplet-Marrow-BM-30m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC1 PXYLP1 PLSCR1

5.19e-041853834157cc14b06bb99ee67ac1526622cf546e727efc
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-C|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

EFEMP1 EGR4 SH3RF2

5.27e-04186383c30fd15f6b4b6edfbdf18a019aaad7fed3cf91fe
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

R3HDM2 SPIDR LGR5

5.27e-04186383de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

R3HDM2 SPIDR LGR5

5.27e-041863830b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCelldroplet-Marrow-nan-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC1 PXYLP1 PLSCR1

5.27e-04186383332931f92352b464c7f23aeebf313cf7db6d499c
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ISLR EFEMP1 PDE10A

5.36e-04187383f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ISLR EFEMP1 PDE10A

5.36e-0418738302e7246ef5ad41773d14426254e139b156d45c1d
ToppCelldroplet-Marrow-BM-1m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC1 PXYLP1 PLSCR1

5.36e-041873836be99f71532b7d679d1287ea1bb08245d9538db7
DiseaseCongenital nystagmus

AHR ATF6

1.53e-062372C0700501
DiseaseNEURAL TUBE DEFECTS, SUSCEPTIBILITY TO

FUZ SCRIB

4.26e-058372C3891448
Diseasebitter non-alcoholic beverage consumption measurement

AHR N4BP2

7.41e-0432372EFO_0010093
Diseasebitter beverage consumption measurement

AHR N4BP2

1.28e-0342372EFO_0010089
Diseaseresponse to fenofibrate

PPARGC1B PDE10A

1.80e-0350372GO_1901557
Diseasesquamous cell carcinoma

AHR PPARGC1B

3.21e-0367372EFO_0000707
DiseaseColorectal Neoplasms

EFEMP1 LGR5 SMAD7

5.02e-03277373C0009404
Diseasemonocyte count

AHR ATF6 R3HDM2 SPIDR CIITA WASF2

5.60e-031320376EFO_0005091
Diseasenevus count, cutaneous melanoma

AHR PPARGC1B

5.84e-0391372EFO_0000389, EFO_0004632
Diseasehippocampal volume

TRAF3IP2 EFEMP1 SMAD7

6.09e-03297373EFO_0005035

Protein segments in the cluster

PeptideGeneStartEntry
LPQTVVCYNPDQIPP

AHR

196

P35869
VCYNPDQIPPENSPL

AHR

201

P35869
TLPCLPLPALFNQEP

CIITA

181

P33076
APLCLDTDQPPYPRQ

ADGRA1

116

Q86SQ6
YIPPPPCQPLINTTE

ATF6

461

P18850
GQPLQYNLSICPPLL

R3HDM2

811

Q9Y2K5
TELILLPPPCPASFN

KCNK6

266

Q9Y257
LPEPNSVPQQYQPCL

ANKRD31

1786

Q8N7Z5
QPCIEPPPSSLLYQP

CYFIP1

26

Q7L576
AASCPQPPTFLLPLL

GPC1

531

P35052
PLPCSAPSVQLSYQP

ISLR

226

O14498
PPLNCPPGLEYLSQI

PLSCR1

91

O15162
PCYTTLTQILPPTEP

PDE10A

726

Q9Y233
PSQCLYEPQLSPPDV

EGR4

271

Q05215
LFCLLPPVPPTQNAL

NAT10

556

Q9H0A0
PLPLTEYIQPVCLPA

HPN

266

P05981
VPLNCPSPVPPLYLD

MTMR4

996

Q9NYA4
QNYTLPCLSPDAQPP

IL31

66

Q6EBC2
VLSCIPAPSLPYNQP

COPG2

686

Q9UBF2
QLSEPCLYPEPLPAL

KPRP

426

Q5T749
PLQCCLPAPPLEPYL

CCDC24

256

Q8N4L8
LCLLCGPSPPLSQLY

FUZ

246

Q9BT04
GPSPPLSQLYPQLLE

FUZ

251

Q9BT04
LPACLNPLLYILFNP

LGR5

811

O75473
PRNPCQDPYILTPEN

EFEMP1

361

Q12805
TYCLPQRKLPPQTPE

PPARGC1B

296

Q86YN6
NLPSLCLPNPEYLAP

SCYL2

221

Q6P3W7
SPLNSLPLYPNHPLC

PXYLP1

146

Q8TE99
LTCYLLPQQPPPSLE

SCRIB

411

Q14160
PLTSVCYPQDLPRPL

TRAF3IP2

226

O43734
ELQIPTPPLPSYCST

STIL

586

Q15468
PAQPPSSYSLPLLLC

SMAD7

146

O15105
LPPPALCYILTAHPN

SPIDR

596

Q14159
TCDTPPPLNNLTPYR

WASF2

126

Q9Y6W5
LQPRPASPCPQVYLE

PRR29

71

P0C7W0
PQPPPLCRALYNFDL

SH3RF2

186

Q8TEC5
DVCEQPPPLNILTPY

WASF1

126

Q92558
SQCRPQELDQPPPYS

TMEM139

101

Q8IV31
PNNPAEYCSTIPPLQ

ZFYVE9

776

O95405
VSYCPVLAPLPLLLP

N4BP2

341

Q86UW6