Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionneuropeptide binding

MRGPRX3 GALR2 MRGPRX1

5.11e-0537393GO:0042923
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

MRGPRX3 GALR2 PTH1R MRGPRX1

1.29e-04133394GO:0008528
GeneOntologyMolecularFunctionneuropeptide receptor activity

MRGPRX3 GALR2 MRGPRX1

1.51e-0453393GO:0008188
GeneOntologyMolecularFunctionpeptide receptor activity

MRGPRX3 GALR2 PTH1R MRGPRX1

1.57e-04140394GO:0001653
GeneOntologyMolecularFunctionubiquitin protein ligase activity

ASB1 ZNRF4 RNF5 MDM2 RNF185

7.47e-04372395GO:0061630
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

MDM2 NR0B2

7.62e-0421392GO:0042975
GeneOntologyMolecularFunctionnuclear retinoid X receptor binding

NSD1 NR0B2

9.16e-0423392GO:0046965
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

ASB1 ZNRF4 RNF5 MDM2 RNF185

1.01e-03398395GO:0061659
GeneOntologyMolecularFunctionnuclear thyroid hormone receptor binding

NSD1 NR0B2

2.00e-0334392GO:0046966
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

ASB1 ZNRF4 RNF5 MDM2 RNF185

2.16e-03473395GO:0004842
GeneOntologyMolecularFunctionubiquitin-like protein conjugating enzyme binding

RNF5 RNF185

3.05e-0342392GO:0044390
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

ASB1 ZNRF4 RNF5 MDM2 RNF185

3.05e-03512395GO:0019787
GeneOntologyMolecularFunctionpeptide binding

MRGPRX3 GALR2 MRGPRX1 CD209

3.35e-03318394GO:0042277
GeneOntologyMolecularFunctionaminoacyltransferase activity

ASB1 ZNRF4 RNF5 MDM2 RNF185

3.59e-03532395GO:0016755
GeneOntologyMolecularFunctionacyltransferase activity

ASB1 ZNRF4 RNF5 MDM2 ZDHHC4 RNF185

3.66e-03775396GO:0016746
GeneOntologyMolecularFunctionpeptide hormone binding

GALR2 PTH1R

5.17e-0355392GO:0017046
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

NSD1 NR0B2

5.17e-0355392GO:0042974
GeneOntologyMolecularFunctionG protein-coupled receptor activity

MRGPRX3 ADGRA2 GALR2 GPR176 PTH1R MRGPRX1

6.92e-03884396GO:0004930
GeneOntologyBiologicalProcessresponse to chloroquine

MRGPRX3 TLR9 MRGPRX1

6.23e-085393GO:1902349
DomainLRRCT

LRIG1 LRRC24 SLIT1 GP9

6.21e-0732404PF01463
DomainCys-rich_flank_reg_C

LRIG1 LRRC24 ADGRA2 SLIT1 GP9

1.34e-0690405IPR000483
DomainLRRCT

LRIG1 LRRC24 ADGRA2 SLIT1 GP9

1.34e-0690405SM00082
DomainLRR_8

TLR9 LRIG1 LRRC24 ADGRA2 SLIT1 GP9

1.60e-06171406PF13855
DomainLeu-rich_rpt

TLR9 LRIG1 LRRC24 ADGRA2 SLIT1 GP9

2.24e-05271406IPR001611
DomainLeu-rich_rpt_typical-subtyp

TLR9 LRIG1 LRRC24 ADGRA2 SLIT1

3.63e-05177405IPR003591
DomainLRR_TYP

TLR9 LRIG1 LRRC24 ADGRA2 SLIT1

3.63e-05177405SM00369
DomainLRRNT

LRIG1 LRRC24 SLIT1 GP9

5.63e-0598404IPR000372
DomainLRRNT

LRIG1 LRRC24 SLIT1 GP9

5.63e-0598404SM00013
Domain-

TLR9 LRIG1 LRRC24 ADGRA2 SLIT1 GP9

5.77e-053214063.80.10.10
DomainL_dom-like

TLR9 LRIG1 LRRC24 ADGRA2 SLIT1 GP9

6.50e-05328406IPR032675
DomainLRR

TLR9 LRIG1 LRRC24 ADGRA2 SLIT1

6.65e-05201405PS51450
DomainLRR_1

TLR9 LRIG1 LRRC24 ADGRA2 SLIT1

9.97e-05219405PF00560
DomainLRRNT

LRIG1 SLIT1 GP9

1.98e-0453403PF01462
DomainMRGPCRFAMILY

MRGPRX3 MRGPRX1

2.43e-0411402IPR026234
DomainIG

ADAMTSL1 MYOM1 LRIG1 LRRC24 ADGRA2 ICAM3

2.54e-04421406SM00409
DomainIg_sub

ADAMTSL1 MYOM1 LRIG1 LRRC24 ADGRA2 ICAM3

2.54e-04421406IPR003599
DomainRING

NSD1 ZNRF4 RNF5 MDM2 RNF185

4.63e-04305405SM00184
DomainIG_LIKE

ADAMTSL1 MYOM1 LRIG1 LRRC24 ADGRA2 ICAM3

5.75e-04491406PS50835
DomainZnf_RING

NSD1 ZNRF4 RNF5 MDM2 RNF185

6.26e-04326405IPR001841
DomainIg-like_dom

ADAMTSL1 MYOM1 LRIG1 LRRC24 ADGRA2 ICAM3

6.53e-04503406IPR007110
DomainIg_I-set

ADAMTSL1 MYOM1 LRIG1 LRRC24

7.12e-04190404IPR013098
DomainI-set

ADAMTSL1 MYOM1 LRIG1 LRRC24

7.12e-04190404PF07679
DomainIGc2

ADAMTSL1 MYOM1 LRIG1 LRRC24

1.56e-03235404SM00408
DomainIg_sub2

ADAMTSL1 MYOM1 LRIG1 LRRC24

1.56e-03235404IPR003598
DomainHRM

ADGRA2 PTH1R

1.63e-0328402PF02793
DomainGPCR_2_secretin-like_CS

ADGRA2 PTH1R

2.40e-0334402IPR017983
Domain-

NSD1 ZNRF4 RNF5 MDM2 RNF185

2.58e-034494053.30.40.10
Domain-

ADAMTSL1 MYOM1 LRIG1 LRRC24 ADGRA2 ICAM3

2.68e-036634062.60.40.10
DomainZnf_RING/FYVE/PHD

NSD1 ZNRF4 RNF5 MDM2 RNF185

2.84e-03459405IPR013083
DomainG_PROTEIN_RECEP_F2_1

ADGRA2 PTH1R

3.31e-0340402PS00649
DomainG_PROTEIN_RECEP_F2_3

ADGRA2 PTH1R

3.31e-0340402PS50227
DomainGPCR_2_extracellular_dom

ADGRA2 PTH1R

3.31e-0340402IPR001879
DomainZF_RING_1

ZNRF4 RNF5 MDM2 RNF185

3.39e-03291404PS00518
DomainIg-like_fold

ADAMTSL1 MYOM1 LRIG1 LRRC24 ADGRA2 ICAM3

3.66e-03706406IPR013783
DomainZF_RING_2

ZNRF4 RNF5 MDM2 RNF185

3.69e-03298404PS50089
DomainG_PROTEIN_RECEP_F2_2

ADGRA2 PTH1R

5.13e-0350402PS00650
Domain7tm_2

ADGRA2 PTH1R

5.13e-0350402PF00002
DomainZnf_C3HC4_RING-type

ZNRF4 RNF5 RNF185

5.91e-03172403IPR018957
DomainGPCR_2-like

ADGRA2 PTH1R

7.32e-0360402IPR017981
DomainGPCR_2_secretin-like

ADGRA2 PTH1R

7.32e-0360402IPR000832
DomainG_PROTEIN_RECEP_F2_4

ADGRA2 PTH1R

7.56e-0361402PS50261
Domainzf-C3HC4

ZNRF4 RNF5 RNF185

1.20e-02223403PF00097
Pubmed

AM3 modulates dendritic cell pathogen recognition capabilities by targeting DC-SIGN.

CD209 ICAM3

1.29e-06240217452477
Pubmed

DC-SIGN binds ICAM-3 isolated from peripheral human leukocytes through Lewis x residues.

CD209 ICAM3

1.29e-06240217145745
Pubmed

The Nuclear Farnesoid X Receptor Reduces p53 Ubiquitination and Inhibits Cervical Cancer Cell Proliferation.

MDM2 NR0B2

1.29e-06240233889569
Pubmed

Functional evaluation of DC-SIGN monoclonal antibodies reveals DC-SIGN interactions with ICAM-3 do not promote human immunodeficiency virus type 1 transmission.

CD209 ICAM3

1.29e-06240212021323
Pubmed

Identification of different binding sites in the dendritic cell-specific receptor DC-SIGN for intercellular adhesion molecule 3 and HIV-1.

CD209 ICAM3

1.29e-06240211799126
Pubmed

Expression of the dendritic cell-associated C-type lectin DC-SIGN by inflammatory matrix metalloproteinase-producing macrophages in rheumatoid arthritis synovium and interaction with intercellular adhesion molecule 3-positive T cells.

CD209 ICAM3

1.29e-06240212571844
Pubmed

Retagging identifies dendritic cell-specific intercellular adhesion molecule-3 (ICAM3)-grabbing non-integrin (DC-SIGN) protein as a novel receptor for a major allergen from house dust mite.

CD209 ICAM3

1.29e-06240222205703
Pubmed

Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses.

CD209 ICAM3

1.29e-06240210721994
Pubmed

Cross-regulation of protein stability by p53 and nuclear receptor SHP.

MDM2 NR0B2

3.87e-06340222737255
Pubmed

DC-SIGN binds to HIV-1 glycoprotein 120 in a distinct but overlapping fashion compared with ICAM-2 and ICAM-3.

CD209 ICAM3

3.87e-06340214970226
Pubmed

Activation of mas-related G-protein-coupled receptors by the house dust mite cysteine protease Der p1 provides a new mechanism linking allergy and inflammation.

MRGPRX3 MRGPRX1

3.87e-06340228768771
Pubmed

The inhibition of high-voltage-activated calcium current by activation of MrgC11 involves phospholipase C-dependent mechanisms.

MRGPRX3 MRGPRX1

3.87e-06340226022362
Pubmed

Investigating the role of MRGPRC11 and capsaicin-sensitive afferent nerves in the anti-influenza effects exerted by SLIGRL-amide in murine airways.

MRGPRX3 MRGPRX1

3.87e-06340227215903
Pubmed

Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs.

MRGPRX3 MRGPRX1

3.87e-06340211850634
Pubmed

Lewis-antigen-containing ICAM-2/3 on Jurkat leukemia cells interact with DC-SIGN to regulate DC functions.

CD209 ICAM3

3.87e-06340229671117
Pubmed

bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells.

MRGPRX3 MRGPRX1

3.87e-06340210662793
Pubmed

A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection.

CD209 ICAM3

3.87e-06340211257134
Pubmed

DC-SIGN-ICAM-2 interaction mediates dendritic cell trafficking.

CD209 ICAM3

3.87e-06340211017109
Pubmed

An autoregulatory feedback loop between Mdm2 and SHP that fine tunes Mdm2 and SHP stability.

MDM2 NR0B2

3.87e-06340222575647
Pubmed

Agonists of the MAS-related gene (Mrgs) orphan receptors as novel mediators of mast cell-sensory nerve interactions.

MRGPRX3 MRGPRX1

3.87e-06340218250432
Pubmed

Mas-related G protein-coupled receptor C11 (Mrgprc11) induces visceral hypersensitivity in the mouse colon: A novel target in gut nociception?

MRGPRX3 MRGPRX1

3.87e-06340231119828
Pubmed

MrgprA3 shows sensitization to chloroquine in an acetone-ether-water mice model.

MRGPRX3 MRGPRX1

7.73e-06440229064954
Pubmed

Activation of MrgprA3 and MrgprC11 on Bladder-Innervating Afferents Induces Peripheral and Central Hypersensitivity to Bladder Distension.

MRGPRX3 MRGPRX1

7.73e-06440233727332
Pubmed

A fraction of mouse sperm chromatin is organized in nucleosomal hypersensitive domains enriched in retroposon DNA.

MRGPRX3 MRGPRX1

7.73e-06440210504302
Pubmed

A mechanically activated ion channel is functionally expressed in the MrgprB4 positive sensory neurons, which detect stroking of hairy skin in mice.

MRGPRX3 MRGPRX1

7.73e-06440228545921
Pubmed

Substance P activates Mas-related G protein-coupled receptors to induce itch.

MRGPRX3 MRGPRX1

7.73e-06440228219706
Pubmed

Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection.

MRGPRX3 MRGPRX1

7.73e-06440235882236
Pubmed

Molecular Signature of Pruriceptive MrgprA3+ Neurons.

MRGPRX3 MRGPRX1

7.73e-06440232234460
Pubmed

Overlap of direct and indirect alloreactive T-cell repertoires when MHC polymorphism is limited to the peptide binding groove.

MRGPRX3 MRGPRX1

7.73e-06440211821156
Pubmed

Cloning and functional expression of a novel Gi protein-coupled receptor for adenine from mouse brain.

MRGPRX3 MRGPRX1

7.73e-06440217975009
Pubmed

Human sensory neuron-specific Mas-related G protein-coupled receptors-X1 sensitize and directly activate transient receptor potential cation channel V1 via distinct signaling pathways.

MRGPRX3 MRGPRX1

7.73e-06440223074220
Pubmed

Characterization of new G protein-coupled adenine receptors in mouse and hamster.

MRGPRX3 MRGPRX1

7.73e-06440223608776
Pubmed

The distinct roles of two GPCRs, MrgprC11 and PAR2, in itch and hyperalgesia.

MRGPRX3 MRGPRX1

7.73e-06440221775281
Pubmed

Voltage-gated potassium channels involved in regulation of physiological function in MrgprA3-specific itch neurons.

MRGPRX3 MRGPRX1

7.73e-06440226874069
Pubmed

Tick peptides evoke itch by activating MrgprC11/MRGPRX1 to sensitize TRPV1 in pruriceptors.

MRGPRX3 MRGPRX1

7.73e-06440233358893
Pubmed

USP48 alleviates bone cancer pain and regulates MrgC stabilization in spinal cord neurons of male mice.

MRGPRX3 MRGPRX1

7.73e-06440236864656
Pubmed

Low maternal care enhances the skin barrier resistance of offspring in mice.

MRGPRX3 MRGPRX1

7.73e-06440231295326
Pubmed

Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo.

LRIG1 LRRC24 ADGRA2

8.23e-063440318848646
Pubmed

Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus.

MRGPRX3 MRGPRX1

1.29e-05540220004959
Pubmed

Activated apoptotic cells induce dendritic cell maturation via engagement of Toll-like receptor 4 (TLR4), dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin (DC-SIGN), and β2 integrins.

CD209 ICAM3

1.29e-05540222396536
Pubmed

Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch.

MRGPRX3 MRGPRX1

1.29e-05540217618277
Pubmed

Hippocampal short- and long-term plasticity are not modulated by astrocyte Ca2+ signaling.

MRGPRX3 MRGPRX1

1.29e-05540220203048
Pubmed

Regional Differences in Itch Transmission.

MRGPRX3 MRGPRX1

1.29e-05540238735364
Pubmed

MrgprB4 in trigeminal neurons expressing TRPA1 modulates unpleasant sensations.

MRGPRX3 MRGPRX1

1.29e-05540234116733
Pubmed

Mdm2 is a novel activator of ApoCIII promoter which is antagonized by p53 and SHP inhibition.

MDM2 NR0B2

1.29e-05540222197810
Pubmed

Astrocytes modulate neural network activity by Ca²+-dependent uptake of extracellular K+.

MRGPRX3 MRGPRX1

1.29e-05540222472648
Pubmed

Cross-sensitization of histamine-independent itch in mouse primary sensory neurons.

MRGPRX3 MRGPRX1

1.29e-05540223000623
Pubmed

A subpopulation of nociceptors specifically linked to itch.

MRGPRX3 MRGPRX1

1.93e-05640223263443
Pubmed

Visualizing the Itch-Sensing Skin Arbors.

MRGPRX3 MRGPRX1

1.93e-05640233091423
Pubmed

Genetic identification of C fibres that detect massage-like stroking of hairy skin in vivo.

MRGPRX3 MRGPRX1

1.93e-05640223364746
Pubmed

Identification of a bilirubin receptor that may mediate a component of cholestatic itch.

MRGPRX3 MRGPRX1

1.93e-05640230657454
Pubmed

Enhanced excitability of MRGPRA3- and MRGPRD-positive nociceptors in a model of inflammatory itch and pain.

MRGPRX3 MRGPRX1

1.93e-05640224549959
Pubmed

Redefining the concept of protease-activated receptors: cathepsin S evokes itch via activation of Mrgprs.

MRGPRX3 MRGPRX1

1.93e-05640226216096
Pubmed

MrgprC11+ sensory neurons mediate glabrous skin itch.

MRGPRX3 MRGPRX1

1.93e-05640233876765
Pubmed

Touch neurons underlying dopaminergic pleasurable touch and sexual receptivity.

MRGPRX3 MRGPRX1

2.70e-05740236693373
Pubmed

RNF185 is a novel E3 ligase of endoplasmic reticulum-associated degradation (ERAD) that targets cystic fibrosis transmembrane conductance regulator (CFTR).

RNF5 RNF185

3.60e-05840224019521
Pubmed

Comparative genomic analysis of eutherian Mas-related G protein-coupled receptor genes.

MRGPRX3 MRGPRX1

3.60e-05840224583173
Pubmed

Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family.

MRGPRX3 MRGPRX1

3.60e-05840212909716
Pubmed

Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway.

MRGPRX3 MRGPRX1

4.62e-05940212397184
Pubmed

Multiplexed peroxidase-based electron microscopy labeling enables simultaneous visualization of multiple cell types.

MRGPRX3 MRGPRX1

4.62e-05940230886406
Pubmed

Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens.

MRGPRX3 MRGPRX1

5.77e-051040233098765
Pubmed

A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons.

MRGPRX3 MRGPRX1

7.05e-051140211551509
Pubmed

An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates.

MRGPRX3 MRGPRX1

7.05e-051140221151121
Pubmed

Parallel ascending spinal pathways for affective touch and pain.

MRGPRX3 MRGPRX1

1.16e-041440233116307
Pubmed

A brain-to-spinal sensorimotor loop for repetitive self-grooming.

MRGPRX3 MRGPRX1

1.34e-041540234932943
Pubmed

DRG afferents that mediate physiologic and pathologic mechanosensation from the distal colon.

MRGPRX3 MRGPRX1

1.34e-041540237541195
Pubmed

Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin.

PDIA6 PTH1R CD209

1.54e-04904031602151
Pubmed

Calcium handling precedes cardiac differentiation to initiate the first heartbeat.

CACNA1H MYOM1

1.73e-041740227725084
Pubmed

Incoherent feed-forward regulatory loops control segregation of C-mechanoreceptors, nociceptors, and pruriceptors.

MRGPRX3 MRGPRX1

1.73e-041740225834056
Pubmed

p75 Is Required for the Establishment of Postnatal Sensory Neuron Diversity by Potentiating Ret Signaling.

MRGPRX3 MRGPRX1

1.95e-041840229045838
Pubmed

C-LTMRs mediate wet dog shakes via the spinoparabrachial pathway.

MRGPRX3 MRGPRX1

2.18e-041940238915692
Pubmed

Tlx3 and Runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors.

MRGPRX3 MRGPRX1

2.18e-041940222787056
Pubmed

Uncoupling of molecular maturation from peripheral target innervation in nociceptors expressing a chimeric TrkA/TrkC receptor.

MRGPRX3 MRGPRX1

2.18e-041940224516396
Pubmed

Meis1 Regulates Nociceptor Development and Behavioral Response to Tactile Stimuli.

MRGPRX3 MRGPRX1

2.42e-042040235875660
Pubmed

ZBTB20 regulates nociception and pain sensation by modulating TRP channel expression in nociceptive sensory neurons.

MRGPRX3 MRGPRX1

2.67e-042140225369838
Pubmed

Hierarchical Specification of Pruriceptors by Runt-Domain Transcription Factor Runx1.

MRGPRX3 MRGPRX1

2.67e-042140228476948
Pubmed

Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.

TLR9 CD209 ICAM3

2.94e-0411240320331378
Pubmed

Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation.

MRGPRX3 MRGPRX1

3.21e-042340220096094
Pubmed

Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain.

MRGPRX3 MRGPRX1

3.21e-042340216446141
Pubmed

A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system.

ZNRF4 RNF5 MDM2

3.43e-0411840319690564
Pubmed

A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons.

MRGPRX3 MRGPRX1

3.50e-042440217553423
Pubmed

TMUB1 is an endoplasmic reticulum-resident escortase that promotes the p97-mediated extraction of membrane proteins for degradation.

RNF5 RNF185

4.12e-042640235961308
Pubmed

Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.

CACNA1H MYOM1 LRIG1

5.66e-0414040326930384
Pubmed

Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-beta signaling.

MRGPRX3 MRGPRX1

5.87e-043140221300867
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

NRM LSS PDIA6 RNF5 LRIG1 RNF185

6.79e-0494240631073040
Pubmed

Identification of transcripts with enriched expression in the developing and adult pancreas.

PDIA6 MYOM1 ZDHHC4 NR0B2 SLIT1

7.16e-0462440518554416
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

LRIG1 LRRC24 ADGRA2

8.64e-0416240325826454
Pubmed

Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse.

PTH1R GOLGA8H

9.30e-043940221606205
Pubmed

HIV-host interactome revealed directly from infected cells.

PDIA6 ICAM3 SLIT1

1.03e-0317240327375898
Pubmed

Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex.

RNF5 RNF185

1.08e-034240232738194
Cytoband11p15.1

MRGPRX3 MRGPRX1

1.27e-036040211p15.1
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

ADAMTSL1 MYOM1 LRIG1 LRRC24

1.39e-04161304593
GeneFamilyG protein-coupled receptors, Class A orphans

MRGPRX3 GPR176 MRGPRX1

2.88e-0478303262
GeneFamilyADAM metallopeptidase domain containing|CD molecules

TLR9 CD209 ICAM3 GP9

3.89e-03394304471
GeneFamilyRing finger proteins

ZNRF4 RNF5 RNF185

1.04e-0227530358
ToppCellPericytes-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 CACNA1H ADAMTSL1 ADGRA2 PTH1R SLIT1

1.09e-08175406ddf721023a7afc8085c5de17aa254a6575444c0f
ToppCellPericytes-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

CACNA1H ADAMTSL1 MYOM1 ADGRA2 PTH1R SLIT1

1.38e-0818240646c213597445b1f4f09dc367f27702d24b201daf
ToppCellPericytes-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 CACNA1H ADGRA2 PTH1R SLIT1

6.18e-071834054617b18da8d699a44e4c47980197b1e7eb951470
ToppCellPericytes-HP_01|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 CACNA1H ADGRA2 PTH1R SLIT1

6.87e-0718740535f25780d113f60bf4c13749013c09612ee4ff41
ToppCellPericytes-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 CACNA1H ADGRA2 GPR176 SLIT1

7.06e-07188405f16ff998393bf1954bbf10caab15173bdb104ac1
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-A|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 CACNA1H MYOM1 ADGRA2 PTH1R

7.83e-07192405fee99ca7e658963acf968aa724ef8c96cfc00a5d
ToppCellPericytes|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 CACNA1H ADGRA2 PTH1R SLIT1

7.83e-07192405057ad22b878c0c5fb59ed1412ca13db945c57a5a
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tfh|GI_large-bowel / Manually curated celltypes from each tissue

CACNA1H ASB1 GALR2 SLIT1

1.37e-051634044104d3b9748b39cb0744c9be76db21bdda566a0d
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

COL4A2 ADAMTSL1 ADGRA2 PTH1R

1.69e-05172404c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 CACNA1H ADGRA2 PTH1R

1.89e-05177404a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 CACNA1H ADGRA2 PTH1R

1.89e-051774043645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCellCOPD-Stromal-SMC|World / Disease state, Lineage and Cell class

COL4A2 CACNA1H ADAMTSL1 PTH1R

1.98e-05179404b2709537ec1b46457ab85261f4cdd354e60a8b29
ToppCellRA-07._Pericyte|RA / Chamber and Cluster_Paper

CACNA1H ADGRA2 GPR176 PTH1R

2.07e-051814048dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCellRA-07._Pericyte|World / Chamber and Cluster_Paper

CACNA1H ADGRA2 GPR176 PTH1R

2.11e-051824042075efeae633550fb2eb026d0dfd741c8252482e
ToppCellPericytes-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 CACNA1H GPR176 SLIT1

2.16e-05183404d04deef7cd4e1738227a6593b84874ce0168c773
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 CACNA1H ADGRA2 PTH1R

2.30e-05186404888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCell10x5'v1-week_17-19-Lymphocytic_B-B_lineage-pre_pro_B_progenitor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PDIA6 XPNPEP2 MDM2 GPR176

2.40e-051884049858940c616e43441644c5a3bea8d832ee4daf79
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 CACNA1H ADGRA2 GPR176

2.55e-0519140404c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 CACNA1H ADGRA2 PTH1R

2.55e-05191404716dfa7fccbd62b5f574792e68a26dc6c45511dc
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 CACNA1H ADGRA2 PTH1R

2.55e-051914041626b23a57429f835fddc052e3c57f63a4e5b8bb
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 CACNA1H ADGRA2 PTH1R

2.60e-0519240409cb5b89a164ac7444774ccc8c90323c8ea2026b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 CACNA1H ADGRA2 PTH1R

2.66e-05193404dd4bac8a93a5b9dcf7301f1d7d6e3eb6670f5c68
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 CACNA1H ADGRA2 PTH1R

2.66e-051934042ddf9b2770a0be9689e01d1a3d19e4a6d42c7a50
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 CACNA1H ADGRA2 PTH1R

2.71e-051944043cffb5c58f6d5bd254f39ee9c41b7e1e4da0ff75
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|lung / Disease (COVID-19 only), tissue and cell type

COL4A2 CACNA1H ADAMTSL1 PTH1R

2.71e-051944045e1e0513a54ec4cf0b247ec85c9fbc68dfac1da3
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 CACNA1H ADGRA2 PTH1R

2.77e-05195404d760d1423f9a8a373fe7b250ea9b1d67a0c0059f
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A2 CACNA1H ADGRA2 PTH1R

2.82e-05196404c373465e34e2dd581247962d59e0477aae877079
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 CACNA1H ADGRA2 PTH1R

2.82e-051964047acd782a587b7d331517f60daa8b5c2177bedfc7
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 CACNA1H ADGRA2 PTH1R

2.82e-0519640473f029d2b276776d6c24356b14c6592c9cb74bd5
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A2 CACNA1H ADGRA2 PTH1R

2.82e-051964048b5337ccf74de90e8b89a02ac00671af1de2cfff
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 CACNA1H MYOM1 ADGRA2

2.88e-05197404bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 CACNA1H ADGRA2 PTH1R

2.88e-0519740401249bd485a3734de87ae6ed9c749597f39c6335
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 CACNA1H ADGRA2 PTH1R

2.88e-05197404983502a99e6d59bb36225b0246a9990604de1a01
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 CACNA1H ADAMTSL1 PTH1R

2.94e-05198404bd42c03e384e64f61b02618cf1a5440033bb04b2
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 CACNA1H MYOM1 ADGRA2

2.94e-051984047dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCellParenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 CACNA1H ADGRA2 PTH1R

3.00e-051994047c272a1aa7f3e931ad5d20809719d85b3bce4cb0
ToppCellParenchyma_COVID-19-Stromal-TX-Smooth_muscle-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

COL4A2 CACNA1H MYOM1 PTH1R

3.00e-05199404c8bc05dece8b8a87d4a7a3e8112b924e15217de1
ToppCellTracheal-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 CACNA1H ADGRA2 GPR176

3.00e-05199404cefc3b50f65e95da850e4720c7b44bf584073491
ToppCellBronchial-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 CACNA1H ADGRA2 PTH1R

3.00e-05199404929f809579368201331d9099d8904b6e3c41797b
ToppCellParenchymal-10x5prime-Stromal-Myofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 CACNA1H ADGRA2 PTH1R

3.00e-0519940420f760d92c351a1dac4cc0a424c443ea03a179fe
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 CACNA1H MYOM1 PTH1R

3.00e-05199404b1753474152b82a0b811b9878c890a359e14919a
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COL4A2 CACNA1H MYOM1 PTH1R

3.00e-0519940478b245d40c1e169ff2d26907b63d732e34529c5f
ToppCellBronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_systemic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 CACNA1H MYOM1 GPR176

3.00e-0519940478a9b26215874a46a910a4b93a51fcac1a597618
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

COL4A2 CACNA1H MYOM1 PTH1R

3.00e-051994048e1e95c3a4b856415af208be6ad977e575bac189
ToppCellBronchial-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 CACNA1H ADGRA2 PTH1R

3.00e-05199404854628ce91068093c14bd4d45ba38c41469f3549
ToppCellTracheal-10x5prime-Stromal-Pericyte-Muscle_pericyte_systemic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 CACNA1H ADGRA2 GPR176

3.00e-05199404aaa460c389cd6d38a13ba1a446f91a94f9573ad8
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COL4A2 CACNA1H ADGRA2 PTH1R

3.05e-0520040443b76e382b38b9856c07557a75e5b1ce0cee1d9e
ToppCellBronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 CACNA1H ADGRA2 PTH1R

3.05e-0520040412326cc6f0af24bacba9493dc79e7c7347db2f41
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

COL4A2 CACNA1H ADGRA2 PTH1R

3.05e-052004040c648941447c738caf62f2d71e296d6cca492c8b
ToppCellBronchial-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 CACNA1H ADGRA2 PTH1R

3.05e-05200404362706445edb33b313684efe50b1f44f5f816e67
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

COL4A2 CACNA1H ADGRA2 PTH1R

3.05e-0520040494f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCelldistal-mesenchymal-Pericyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A2 CACNA1H ADGRA2 PTH1R

3.05e-05200404867935701fac71a3fe01578362da0676f959736c
ToppCellParenchymal-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 CACNA1H ADGRA2 PTH1R

3.05e-05200404f9bc22ff17bb1c751e6b05bca3f403836f33459a
ToppCelldistal-mesenchymal-Pericyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL4A2 CACNA1H ADGRA2 PTH1R

3.05e-05200404fe31287cfb51d45643bdedbaa5efc03ed87263c6
ToppCellParenchymal-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 CACNA1H ADGRA2 PTH1R

3.05e-052004040a7640db28c708003d5da2d19eb651f6fedfd710
ToppCellParenchyma_COVID-19-Stromal-TX-Smooth_muscle-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

COL4A2 CACNA1H ADGRA2 PTH1R

3.05e-0520040478e9a40153d7ba5d9ea6393a37d26fc5c0220867
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COL4A2 CACNA1H ADGRA2 PTH1R

3.05e-05200404522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

COL4A2 CACNA1H ADGRA2 PTH1R

3.05e-05200404c46e06b4f22d3456e67bc62a9ac198e8041965ad
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NRM MYOM1 LRIG1

2.85e-041434035a279da1cd8e63db32f7c85a73b493c2121d0a96
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_bronchial_vessel-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZSCAN16 OVCH1 NR0B2

2.91e-04144403748f4efc59f7afbce6c497524f36d852b8b1d637
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NRM MYOM1 LRIG1

2.97e-04145403997bd540c43725a85ca97e4b79ebe0d336860287
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_bronchial_vessel|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZSCAN16 OVCH1 NR0B2

3.03e-04146403df865558d1843f3857ebd1529cebc540d3554c59
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

LRRC24 GPR176 PTH1R

3.41e-04152403621e9b33cd3bb1c7b7d0633069f286b203e3d9c0
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 CACNA1H PTH1R

3.82e-0415840384c0a215dabf697ada036c2b9592d0c61b5077de
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 ADGRA2 PTH1R

3.82e-0415840332c95c1bc9e50fccd6d06e828f29258fc5e568cb
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

ADAMTSL1 ADGRA2 PTH1R

3.96e-04160403fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_8|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SVOP GPR176 UNC5CL

4.03e-041614037e0b8119cea208c0b4a0dffdf94ff6137d0b4c90
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

COL4A2 CACNA1H GPR176

4.03e-0416140347b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_8|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SVOP GPR176 UNC5CL

4.11e-041624032fd6e8f48b48d509a7533cec2f79089513c34a2f
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1H GPR176 PTH1R

4.18e-0416340351dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCellBAL-Severe-cDC_8|Severe / Compartment, Disease Groups and Clusters

SVOP GPR176 UNC5CL

4.25e-04164403e8cbe7e01eca32886eb44e02d5333056b6bebc50
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NTN5 SVOP SLIT1

4.49e-041674033dfec2fcc36caa6e394efae5e540a6fa28759977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NTN5 SVOP SLIT1

4.49e-0416740395b3b5ba3414729f0460a26a0deca48de0cbe33e
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic|TCGA-Mesothelium / Sample_Type by Project: Shred V9

COL4A2 NRM ADGRA2

4.49e-041674039062577a4b7902c9a888d706589d1b05221c0fa8
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NTN5 SVOP SLIT1

4.49e-041674039480739587d51e67a281778b9bddd7b5ffc3ad92
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

XPNPEP2 ADGRA2 CD209

4.56e-04168403aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZSCAN16 LRRC24 GPR176

4.64e-04169403606aa4ff25380d9470ec116ca86cd20f8b19587a
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZSCAN16 LRRC24 GPR176

4.64e-04169403052aae2af5446a0de071d5dda5381b0b9a0ed54d
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRIG1 GPR176 PTH1R

4.72e-041704038465c3069bbc08705d070927e712b6bc85ac7c5b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 OVCH1 ADGRA2

4.72e-04170403876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 OVCH1 ADGRA2

4.72e-041704031f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL4A2 ADGRA2 PTH1R

4.81e-04171403a4a2c5dc995589fbe3d4ca6ee1df888807e4ae34
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

COL4A2 CACNA1H PTH1R

4.81e-04171403080003f698f867935c2bfc55d241d3650f45a0ab
ToppCellControl-Stromal-Pericyte|World / Disease state, Lineage and Cell class

COL4A2 CACNA1H PTH1R

4.89e-04172403813d4256b05b66ca11b08cc0026459d79f12c0eb
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL4A2 PTH1R ICAM3

4.89e-041724032b0333c21b7472194a7b9feb3de121da3340fc5b
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

COL4A2 ADAMTSL1 ADGRA2

4.89e-04172403c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCellAdult-Mesenchymal-pericyte_cell-D231|Adult / Lineage, Cell type, age group and donor

COL4A2 CACNA1H ADGRA2

4.89e-04172403858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A2 ADAMTSL1 MYOM1

4.97e-04173403cb6389536195443633adb06e5f1b7483530773d1
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MDM2 LRRC24 UNC5CL

4.97e-04173403b9dee61973559e8c2fef3f2dafd43475b386befb
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 CACNA1H PTH1R

4.97e-041734035416b092321c7d9b63f0418c60f2402a138355bf
ToppCellmetastatic_Lymph_Node-Endothelial_cells-Lymphatic_ECs|metastatic_Lymph_Node / Location, Cell class and cell subclass

COL4A2 ADGRA2 GPR176

5.06e-04174403d551bc29afef071adf4c9bb80345352ec33441d8
ToppCellControl-Stromal-Pericyte|Control / Disease state, Lineage and Cell class

COL4A2 CACNA1H PTH1R

5.06e-0417440391fc1f1c891f105a91968c22e2de5321c52b439a
ToppCelldroplet-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRM TLR9 UNC5CL

5.06e-04174403ce9bdd02dc8eb45ba9c1481619c0089b465e6442
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 ADAMTSL1 GPR176

5.14e-04175403f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma-4|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

XPNPEP2 MDM2 CD209

5.14e-0417540316849ea8f0985108baa2085f34c3de14a4f9f28b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 ADAMTSL1 GPR176

5.14e-04175403910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1H ADAMTSL1 SLIT1

5.14e-0417540390e29945aa861082c94bb4f331161adc3a6ef899
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASB1 NR0B2 SLIT1

5.23e-041764033766e0533b103ec92ac75eba3df02e287efc53fa
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

XPNPEP2 UNC5CL PTH1R

5.23e-041764031595dbeee336a81e581325d63208ec6262664ee9
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASB1 NR0B2 SLIT1

5.23e-04176403aa1bada2175d8370fc71939a607407155259d195
DrugThalidomide [50-35-1]; Up 200; 15.4uM; MCF7; HT_HG-U133A

CACNA1H ARSD MDM2 SHFL GPR176

2.26e-051954055990_UP
DrugPentetic acid [67-43-6]; Up 200; 10.2uM; HL60; HT_HG-U133A

ARSD ZNRF4 GALR2 PTH1R CD209

2.31e-051964053049_UP
DrugCefuroxime sodium salt [56238-63-2]; Up 200; 9uM; MCF7; HT_HG-U133A

NEU3 ASB1 ADGRA2 SHFL GPR176

2.43e-051984056088_UP
DrugPhentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A

NEU3 LSS ASB1 MDM2 NR0B2

2.55e-052004052323_UP
DrugTetracycline hydrochloride [64-75-5]; Up 200; 8.4uM; HL60; HG-U133A

XPNPEP2 ZNRF4 ADGRA2 SHFL PIEZO1

2.55e-052004051397_UP
DiseaseLipoidosis

LSS NR0B2

2.87e-0419392C0023794
Diseasepulmonary tuberculosis (is_implicated_in)

TLR9 CD209

1.42e-0342392DOID:2957 (is_implicated_in)
DiseaseHallux valgus

UNC5CL SLIT1

2.87e-0360392HP_0001822

Protein segments in the cluster

PeptideGeneStartEntry
NILWKPWLQPCCGHF

ARSD

566

P51689
FLTCDCHLRWLLPWA

ADGRA2

191

Q96PE1
VWCCGWLPCTPLRIA

ASB1

71

Q9Y576
DVSIPHCPAGWRSLW

COL4A2

1606

P08572
KAAVERLCHPCPWEW

CD209

246

Q9NNX6
RLCHPCPWEWTFFQG

CD209

251

Q9NNX6
WWPCRICSDPLINTH

NSD1

336

Q96L73
SFLCDCQLKWLPPWL

LRIG1

441

Q96JA1
PFDIILSTSPHCCWW

GPR176

96

Q14439
HLCSWGPRPANWQRC

ADAMTSL1

1706

Q8N6G6
WAPAHPSTLWCHCRQ

LSS

221

P48449
LTENPWRCDCALHWL

LRRC24

201

Q50LG9
EPWATWVPLLCFVLH

NRM

131

Q8IXM6
CLSILWPIWYHCRRP

MRGPRX3

121

Q96LB0
HWVLCEVLEPWCPAA

NR0B2

196

Q15466
PSVLWPRACWTLLVC

ICAM3

6

P32942
CLCWMPHHALILCVW

GALR2

246

O43603
PWHCDCSLTYLRLWL

GP9

86

P14770
CKAPERSCPHTWWVP

C5orf60

286

A6NFR6
NCCVPLLCWAWLPRR

GOLGA8H

616

P0CJ92
SWCLRLVCNPWFEHV

CACNA1H

91

O95180
YAPWCGHCQRLTPEW

PDIA6

51

Q15084
ILAPQLHCEWRLPSW

SVOP

106

Q8N4V2
YCWPCLHQWLETRPE

RNF5

46

Q99942
CESCRPSHRDWPWRP

NTN5

186

Q8WTR8
ACPHCWPWQVGLRFL

OVCH1

581

Q7RTY7
PSHCNRCWALRENWL

MDM2

316

Q00987
CLSVLWPIWYRCHRP

MRGPRX1

121

Q96LB2
PLEAACWSRPWILHC

NEU3

351

Q9UQ49
ACSSCDHVWWRRVPQ

SHFL

111

Q9NUL5
RPCLPEWDHILCWPL

PTH1R

106

Q03431
CFHLCLAWLPWRGRQ

TLR9

846

Q9NR96
AWCQRCPLVAWPPSA

ZDHHC4

296

Q9NPG8
WLWAQACCSHRRPVK

ZNRF4

276

Q8WWF5
LRWHCPRRLLGACWT

UNC5CL

31

Q8IV45
HLFCWPCLHQWLETR

RNF185

56

Q96GF1
QLWELCRQWLRPECH

ZSCAN16

61

Q9H4T2
LFLALCTWWACHFPI

PIEZO1

226

Q92508
MARAHWGCCPWLVLL

XPNPEP2

1

O43895
WLVLLCACAWGHTKP

XPNPEP2

11

O43895
NPLYCDCHLRWLSSW

SLIT1

866

O75093
WQRCPDDVSHRFWCP

ZMYND15

346

Q9H091
LHCSIAGWPEPRVTW

MYOM1

296

P52179