Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	mRNA (nucleoside-2'-O-)-methyltransferase activity	CMTR1 CMTR2	2.64e-05	2	103	2	GO:0004483
GeneOntologyMolecularFunction	purine ribonucleotide transmembrane transporter activity	SLC25A24 SLC35B2 SLC19A1	2.19e-04	23	103	3	GO:0005346
GeneOntologyMolecularFunction	transporter activity	SLC25A24 ATP6V1A ATP7A NOX5 SLC6A17 APOB SLC35B2 GRIN2A KCNB2 SLC30A5 SLC25A2 SLC19A1 SURF1 SCN2A SCN3A KCNN4 ANO3	3.06e-04	1289	103	17	GO:0005215
GeneOntologyMolecularFunction	adenine nucleotide transmembrane transporter activity	SLC25A24 SLC35B2 SLC19A1	3.18e-04	26	103	3	GO:0000295
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC25A24 ATP6V1A ATP7A NOX5 SLC6A17 SLC35B2 GRIN2A KCNB2 SLC30A5 SLC25A2 SLC19A1 SURF1 SCN2A SCN3A KCNN4 ANO3	3.46e-04	1180	103	16	GO:0022857
GeneOntologyMolecularFunction	purine nucleotide transmembrane transporter activity	SLC25A24 SLC35B2 SLC19A1	4.42e-04	29	103	3	GO:0015216
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC25A24 ATP6V1A ATP7A NOX5 GRIN2A KCNB2 SLC30A5 SURF1 SCN2A SCN3A KCNN4 ANO3	5.31e-04	758	103	12	GO:0015318
GeneOntologyMolecularFunction	mitogen-activated protein kinase p38 binding	DUSP10 PRKG1	5.44e-04	7	103	2	GO:0048273
GeneOntologyMolecularFunction	GTPase binding	ATP7A TBC1D30 IQGAP1 PTPRN RABGAP1L DIAPH1 DIAPH2 GOLGA4	5.55e-04	360	103	8	GO:0051020
GeneOntologyMolecularFunction	nucleotide transmembrane transporter activity	SLC25A24 SLC35B2 SLC19A1	6.50e-04	33	103	3	GO:0015215
GeneOntologyMolecularFunction	TPR domain binding	PDE2A HSP90AB1	7.23e-04	8	103	2	GO:0030911
GeneOntologyMolecularFunction	antiporter activity	SLC25A24 SLC35B2 SLC30A5 SLC25A2 SLC19A1	7.46e-04	138	103	5	GO:0015297
GeneOntologyMolecularFunction	mitogen-activated protein kinase binding	IQGAP1 DUSP10 PRKG1	7.74e-04	35	103	3	GO:0051019
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	ATP6V1A ATP7A NOX5 GRIN2A KCNB2 SLC30A5 SLC19A1 SURF1 SCN2A SCN3A KCNN4 ANO3	7.89e-04	793	103	12	GO:0015075
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC25A24 ATP6V1A ATP7A SLC6A17 SLC35B2 SLC30A5 SLC25A2 SLC19A1 SURF1	8.10e-04	477	103	9	GO:0022804
GeneOntologyMolecularFunction	cyclic nucleotide binding	PDE2A SLC19A1 PRKG1	1.06e-03	39	103	3	GO:0030551
GeneOntologyMolecularFunction	organophosphate ester transmembrane transporter activity	SLC25A24 SLC35B2 SLC19A1	1.06e-03	39	103	3	GO:0015605
GeneOntologyMolecularFunction	MAP kinase tyrosine phosphatase activity	DUSP8 DUSP10	1.15e-03	10	103	2	GO:0033550
GeneOntologyMolecularFunction	small GTPase binding	ATP7A TBC1D30 IQGAP1 RABGAP1L DIAPH1 DIAPH2 GOLGA4	1.38e-03	321	103	7	GO:0031267
GeneOntologyMolecularFunction	protein tyrosine/threonine phosphatase activity	DUSP8 DUSP10	1.41e-03	11	103	2	GO:0008330
GeneOntologyMolecularFunction	ATP-dependent protein binding	PLA2G6 HSP90AB1	1.41e-03	11	103	2	GO:0043008
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	ATP6V1A ATP7A NOX5 GRIN2A KCNB2 SLC30A5 SURF1 SCN2A SCN3A KCNN4	1.49e-03	627	103	10	GO:0022890
GeneOntologyMolecularFunction	MAP kinase tyrosine/serine/threonine phosphatase activity	DUSP8 DUSP10	1.98e-03	13	103	2	GO:0017017
GeneOntologyMolecularFunction	mRNA methyltransferase activity	CMTR1 CMTR2	1.98e-03	13	103	2	GO:0008174
GeneOntologyMolecularFunction	monoatomic cation channel activity	ATP6V1A NOX5 GRIN2A KCNB2 SCN2A SCN3A KCNN4	2.01e-03	343	103	7	GO:0005261
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	ATP6V1A ATP7A NOX5 GRIN2A KCNB2 SLC30A5 SURF1 SCN2A SCN3A KCNN4	2.27e-03	664	103	10	GO:0008324
GeneOntologyMolecularFunction	sodium ion binding	SCN2A SCN3A	2.30e-03	14	103	2	GO:0031402
GeneOntologyBiologicalProcess	axon midline choice point recognition	DIAPH1 DIAPH2 ROBO3	4.05e-06	7	102	3	GO:0016199
GeneOntologyBiologicalProcess	axon choice point recognition	DIAPH1 DIAPH2 ROBO3	9.65e-06	9	102	3	GO:0016198
MousePheno	abnormal mitotic spindle assembly checkpoint	KIF18A BUB1 WDR62	8.48e-06	8	76	3	MP:0009762
Domain	NPIP	NPIPA1 NPIPA7 NPIPA5 NPIPA3	8.05e-07	14	102	4	IPR009443
Domain	Kelch_1	KLHL10 KLHL9 MKLN1 KBTBD12 KLHL18	4.02e-05	70	102	5	PF01344
Domain	Kelch_1	KLHL10 KLHL9 MKLN1 KBTBD12 KLHL18	4.02e-05	70	102	5	IPR006652
Domain	BTB-kelch_protein	KLHL10 KLHL9 KBTBD12 KLHL18	8.78e-05	43	102	4	IPR017096
Domain	Drf_DAD	DIAPH1 DIAPH2	8.83e-05	3	102	2	PF06345
Domain	Drf_DAD	DIAPH1 DIAPH2	8.83e-05	3	102	2	IPR010465
Domain	Kelch	KLHL10 KLHL9 KBTBD12 KLHL18	2.84e-04	58	102	4	SM00612
Domain	FtsJ	CMTR1 CMTR2	2.92e-04	5	102	2	PF01728
Domain	rRNA_MeTrfase_FtsJ_dom	CMTR1 CMTR2	2.92e-04	5	102	2	IPR002877
Domain	Gal_Oxase/kelch_b-propeller	KLHL10 KLHL9 MKLN1 KLHL18	3.03e-04	59	102	4	IPR011043
Domain	BACK	KLHL10 KLHL9 KBTBD12 KLHL18	3.23e-04	60	102	4	SM00875
Domain	BACK	KLHL10 KLHL9 KBTBD12 KLHL18	3.45e-04	61	102	4	IPR011705
Domain	BACK	KLHL10 KLHL9 KBTBD12 KLHL18	3.45e-04	61	102	4	PF07707
Domain	-	KLHL10 KLHL9 KLHL18	4.21e-04	27	102	3	2.130.10.80
Domain	Na_trans_cytopl	SCN2A SCN3A	4.37e-04	6	102	2	PF11933
Domain	Na_trans_cytopl	SCN2A SCN3A	4.37e-04	6	102	2	IPR024583
Domain	DAD_dom	DIAPH1 DIAPH2	8.09e-04	8	102	2	IPR014767
Domain	DAD	DIAPH1 DIAPH2	8.09e-04	8	102	2	PS51231
Domain	Gal_Oxidase_b-propeller	KLHL10 KLHL9 KLHL18	8.37e-04	34	102	3	IPR015916
Domain	EF-hand-dom_pair	SLC25A24 CFAP251 MYL3 NOX5 ZZEF1 PLCD3 SCN3A	1.00e-03	287	102	7	IPR011992
Domain	Calx_beta	ADGRV1 FREM1	1.04e-03	9	102	2	IPR003644
Domain	Drf_GBD	DIAPH1 DIAPH2	1.04e-03	9	102	2	PF06371
Domain	Drf_FH3	DIAPH1 DIAPH2	1.04e-03	9	102	2	PF06367
Domain	FH3_dom	DIAPH1 DIAPH2	1.04e-03	9	102	2	IPR010472
Domain	GTPase-bd	DIAPH1 DIAPH2	1.04e-03	9	102	2	IPR010473
Domain	Drf_FH3	DIAPH1 DIAPH2	1.04e-03	9	102	2	SM01139
Domain	Calx-beta	ADGRV1 FREM1	1.04e-03	9	102	2	PF03160
Domain	Drf_GBD	DIAPH1 DIAPH2	1.04e-03	9	102	2	SM01140
Domain	Na_channel_asu	SCN2A SCN3A	1.29e-03	10	102	2	IPR001696
Domain	Na_trans_assoc	SCN2A SCN3A	1.29e-03	10	102	2	IPR010526
Domain	Na_trans_assoc	SCN2A SCN3A	1.29e-03	10	102	2	PF06512
Domain	MKP	DUSP8 DUSP10	1.29e-03	10	102	2	IPR008343
Domain	GBD/FH3_dom	DIAPH1 DIAPH2	1.57e-03	11	102	2	IPR014768
Domain	GBD_FH3	DIAPH1 DIAPH2	1.57e-03	11	102	2	PS51232
Domain	WW	CMTR1 IQGAP1 SETD2	2.15e-03	47	102	3	PF00397
Domain	-	ACOX2 IVD	2.22e-03	13	102	2	1.10.540.10
Domain	AcylCoA_DH/ox_N	ACOX2 IVD	2.22e-03	13	102	2	IPR013786
Domain	WW	CMTR1 IQGAP1 SETD2	2.29e-03	48	102	3	SM00456
Domain	ARM-type_fold	USP34 USP9X MROH5 APOB DIAPH1 DIAPH2 NIPBL	2.58e-03	339	102	7	IPR016024
Domain	WW_DOMAIN_1	CMTR1 IQGAP1 SETD2	2.72e-03	51	102	3	PS01159
Domain	WW_DOMAIN_2	CMTR1 IQGAP1 SETD2	2.72e-03	51	102	3	PS50020
Domain	WW_dom	CMTR1 IQGAP1 SETD2	2.88e-03	52	102	3	IPR001202
Domain	Acyl-CoA_Oxase/DH_cen-dom	ACOX2 IVD	2.96e-03	15	102	2	IPR006091
Domain	AcylCoA_DH/oxidase_NM_dom	ACOX2 IVD	2.96e-03	15	102	2	IPR009100
Domain	FH2	DIAPH1 DIAPH2	2.96e-03	15	102	2	PS51444
Domain	FH2_Formin	DIAPH1 DIAPH2	2.96e-03	15	102	2	IPR015425
Domain	FH2	DIAPH1 DIAPH2	2.96e-03	15	102	2	PF02181
Domain	Acyl-CoA_dh_M	ACOX2 IVD	2.96e-03	15	102	2	PF02770
Domain	FH2	DIAPH1 DIAPH2	2.96e-03	15	102	2	SM00498
Domain	BTB	KLHL10 KCNB2 KLHL9 KBTBD12 KLHL18	3.08e-03	180	102	5	SM00225
Domain	-	SLC25A24 CFAP251 MYL3 NOX5 ZZEF1 PLCD3	3.09e-03	261	102	6	1.10.238.10
Domain	AcylCo_DH/oxidase_C	ACOX2 IVD	3.37e-03	16	102	2	IPR009075
Domain	BTB/POZ_dom	KLHL10 KCNB2 KLHL9 KBTBD12 KLHL18	3.47e-03	185	102	5	IPR000210
Domain	SKP1/BTB/POZ	KLHL10 KCNB2 KLHL9 KBTBD12 KLHL18	3.80e-03	189	102	5	IPR011333
Pubmed	Novel retinal and cone photoreceptor transcripts revealed by human macular expression profiling.	NPIPA1 NPIPA5 NPIPA3	1.13e-07	4	107	3	18055785
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	USP34 CWF19L2 USP9X BCOR POLR3C SETD2 ZNF644 BUB1 DIAPH1 CDK11B PIP4K2C CDC23	2.81e-07	588	107	12	38580884
Pubmed	Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.	SCN2A SCN3A	9.38e-06	2	107	2	20346423
Pubmed	2'-O-ribose methylation of cap2 in human: function and evolution in a horizontally mobile family.	CMTR1 CMTR2	9.38e-06	2	107	2	21310715
Pubmed	The scaffold-protein IQGAP1 enhances and spatially restricts the actin-nucleating activity of Diaphanous-related formin 1 (DIAPH1).	IQGAP1 DIAPH1	9.38e-06	2	107	2	32005666
Pubmed	Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.	SCN2A SCN3A	9.38e-06	2	107	2	11245985
Pubmed	The core FH2 domain of diaphanous-related formins is an elongated actin binding protein that inhibits polymerization.	DIAPH1 DIAPH2	9.38e-06	2	107	2	14992721
Pubmed	Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.	SCN2A SCN3A	9.38e-06	2	107	2	23016767
Pubmed	Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.	SCN2A SCN3A	9.38e-06	2	107	2	27153334
Pubmed	Lysine metabolism is a novel metabolic tumor suppressor pathway in breast cancer.	MC4R PPARG	9.38e-06	2	107	2	37393340
Pubmed	mDia1/3 generate cortical F-actin meshwork in Sertoli cells that is continuous with contractile F-actin bundles and indispensable for spermatogenesis and male fertility.	DIAPH1 DIAPH2	9.38e-06	2	107	2	30256801
Pubmed	Positive selection of a gene family during the emergence of humans and African apes.	NPIPA1 NPIPA8	9.38e-06	2	107	2	11586358
Pubmed	Diaphanous 1 and 2 regulate smooth muscle cell differentiation by activating the myocardin-related transcription factors.	DIAPH1 DIAPH2	9.38e-06	2	107	2	17170370
Pubmed	Functional integrity of the contractile actin cortex is safeguarded by multiple Diaphanous-related formins.	DIAPH1 DIAPH2	9.38e-06	2	107	2	30808751
Pubmed	Structural analysis of human 2'-O-ribose methyltransferases involved in mRNA cap structure formation.	CMTR1 CMTR2	9.38e-06	2	107	2	24402442
Pubmed	Distinct functions of diaphanous-related formins regulate HIV-1 uncoating and transport.	DIAPH1 DIAPH2	9.38e-06	2	107	2	28760985
Pubmed	Deficiency of mDia, an actin nucleator, disrupts integrity of neuroepithelium and causes periventricular dysplasia.	DIAPH1 DIAPH2	9.38e-06	2	107	2	21980468
Pubmed	Hsp90 chaperones PPARγ and regulates differentiation and survival of 3T3-L1 adipocytes.	PPARG HSP90AB1	9.38e-06	2	107	2	24096869
Pubmed	CHARGE syndrome-associated CHD7 acts at ISL1-regulated enhancers to modulate second heart field gene expression.	SEMA3C FOXF1 TBX5	1.25e-05	15	107	3	37052590
Pubmed	Voltage-gated sodium channels in taste bud cells.	SCN2A SCN3A	2.81e-05	3	107	2	19284629
Pubmed	Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation.	IQGAP1 DIAPH1	2.81e-05	3	107	2	17620407
Pubmed	PBRM1, SETD2 and BAP1 - the trinity of 3p in clear cell renal cell carcinoma.	SETD2 PBRM1	2.81e-05	3	107	2	36253570
Pubmed	SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.	SCN2A SCN3A	2.81e-05	3	107	2	23859570
Pubmed	Expression and Mutation Patterns of PBRM1, BAP1 and SETD2 Mirror Specific Evolutionary Subtypes in Clear Cell Renal Cell Carcinoma.	SETD2 PBRM1	2.81e-05	3	107	2	30660076
Pubmed	mDia and ROCK Mediate Actin-Dependent Presynaptic Remodeling Regulating Synaptic Efficacy and Anxiety.	DIAPH1 DIAPH2	2.81e-05	3	107	2	27880913
Pubmed	Seeking genetic determinants of selected metabolic disorders in women aged 45-60.	MC4R PPARG	2.81e-05	3	107	2	32955223
Pubmed	Obesity and eating behaviour in children and adolescents: contribution of common gene polymorphisms.	MC4R PPARG	2.81e-05	3	107	2	22724641
Pubmed	Sodium channels SCN1A, SCN2A and SCN3A in familial autism.	SCN2A SCN3A	2.81e-05	3	107	2	12610651
Pubmed	Chlamydia pneumoniae induces macrophage-derived foam cell formation via PPAR alpha and PPAR gamma-dependent pathways.	APOB PPARG	2.81e-05	3	107	2	19114110
Pubmed	Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.	SCN2A SCN3A	2.81e-05	3	107	2	18784617
Pubmed	Relationships between FTO rs9939609, MC4R rs17782313, and PPARγ rs1801282 polymorphisms and the occurrence of selected metabolic and hormonal disorders in middle-aged and elderly men - a preliminary study.	MC4R PPARG	2.81e-05	3	107	2	27920511
Pubmed	Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.	SCN2A SCN3A	2.81e-05	3	107	2	17544618
Pubmed	Identification of functional voltage-gated Na(+) channels in cultured human pulmonary artery smooth muscle cells.	SCN2A SCN3A	2.81e-05	3	107	2	16052353
Pubmed	15-Deoxy-delta12,14-prostaglandin J2 regulates leukemia inhibitory factor signaling through JAK-STAT pathway in mouse embryonic stem cells.	PPARG JAK1	2.81e-05	3	107	2	16737695
Pubmed	A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway.	PPARG NR1I2	2.81e-05	3	107	2	16556603
Pubmed	Genomic aberrations frequently alter chromatin regulatory genes in chordoma.	SETD2 PBRM1	2.81e-05	3	107	2	27072194
Pubmed	Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.	SCN2A SCN3A	2.81e-05	3	107	2	14973256
Pubmed	Evidences on three relevant obesogenes: MC4R, FTO and PPARγ. Approaches for personalized nutrition.	MC4R PPARG	2.81e-05	3	107	2	21207518
Pubmed	Computational analysis of the mutations in BAP1, PBRM1 and SETD2 genes reveals the impaired molecular processes in renal cell carcinoma.	SETD2 PBRM1	2.81e-05	3	107	2	26452128
Pubmed	Essential roles of RNA cap-proximal ribose methylation in mammalian embryonic development and fertility.	CMTR1 CMTR2	2.81e-05	3	107	2	37436893
Pubmed	Essential and nonredundant roles for Diaphanous formins in cortical microtubule capture and directed cell migration.	DIAPH1 DIAPH2	2.81e-05	3	107	2	24403606
Pubmed	Tbx1 coordinates addition of posterior second heart field progenitor cells to the arterial and venous poles of the heart.	SEMA3C PPARG TBX5	3.11e-05	20	107	3	25190705
Pubmed	Tbx5 and Osr1 interact to regulate posterior second heart field cell cycle progression for cardiac septation.	MYL3 FOXF1 TBX5	3.62e-05	21	107	3	25986147
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	PDE2A USP9X GRIN2A BCOR IQGAP1 PBRM1 DIAPH1 DIAPH2 PIP4K2C NIPBL GOLGA4 HSP90AB1	4.22e-05	963	107	12	28671696
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	KIF18A DUSP10 NIPBL WDR62 CDC23 HSP90AB1	4.91e-05	210	107	6	16565220
Pubmed	Association between LEPR, FTO, MC4R, and PPARG-2 polymorphisms with obesity traits and metabolic phenotypes in school-aged children.	MC4R PPARG	5.60e-05	4	107	2	29679223
Pubmed	Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.	SCN2A SCN3A	5.60e-05	4	107	2	17537961
Pubmed	Expression and distribution of key enzymes of the cyclic GMP signaling in the human clitoris: relation to phosphodiesterase type 5 (PDE5).	PDE2A PRKG1	5.60e-05	4	107	2	21697861
Pubmed	Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms.	SETD2 SCN2A	5.60e-05	4	107	2	26637798
Pubmed	Pathogenicity of lupus anti-ribosomal P antibodies: role of cross-reacting neuronal surface P antigen in glutamatergic transmission and plasticity in a mouse model.	GRIN2A ZZEF1	5.60e-05	4	107	2	25709106
Pubmed	Obesity-related genetic polymorphisms and adiposity indices in a young Italian population.	MC4R PPARG	5.60e-05	4	107	2	28090739
Pubmed	Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.	SCN2A SCN3A	5.60e-05	4	107	2	35801810
Pubmed	Loss of a Rho-regulated actin nucleator, mDia2, impairs cytokinesis during mouse fetal erythropoiesis.	DIAPH1 DIAPH2	5.60e-05	4	107	2	24239357
Pubmed	Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.	SCN2A SCN3A	5.60e-05	4	107	2	35031483
Pubmed	Polymorphisms in NF-κB, PXR, LXR, PPARγ and risk of inflammatory bowel disease.	PPARG NR1I2	5.60e-05	4	107	2	21245992
Pubmed	Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.	SCN2A SCN3A	5.60e-05	4	107	2	29578003
Pubmed	EphA4-dependent axon retraction and midline localization of Ephrin-B3 are disrupted in the spinal cord of mice lacking mDia1 and mDia3 in combination.	DIAPH1 DIAPH2	5.60e-05	4	107	2	23890216
Pubmed	Rho activation of mDia formins is modulated by an interaction with inverted formin 2 (INF2).	DIAPH1 DIAPH2	5.60e-05	4	107	2	21278336
Pubmed	Aberrant promoter hypermethylation of PBRM1, BAP1, SETD2, KDM6A and other chromatin-modifying genes is absent or rare in clear cell RCC.	SETD2 PBRM1	5.60e-05	4	107	2	23644518
Pubmed	Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis.	PPARG NR1I2	5.60e-05	4	107	2	18242221
Pubmed	Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.	SCN2A SCN3A	5.60e-05	4	107	2	8974318
Pubmed	Dysregulation of TBX1 dosage in the anterior heart field results in congenital heart disease resembling the 22q11.2 duplication syndrome.	SEMA3C MYL3 TBX5	6.20e-05	25	107	3	29509905
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	USP34 PPP1R13L SETD2 KLHL9 CCDC47 GPATCH11 DIAPH1 CDK11B GOLGA4 WDR62	9.10e-05	733	107	10	34672954
Pubmed	Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.	SCN2A SCN3A	9.32e-05	5	107	2	1679748
Pubmed	A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.	SCN2A SCN3A	9.32e-05	5	107	2	8812438
Pubmed	Protein kinase G signaling disrupts Rac1-dependent focal adhesion assembly in liver specific pericytes.	IQGAP1 PRKG1	9.32e-05	5	107	2	21451103
Pubmed	[Genetic Predictors of Unfavorable Course in High Risk Patients With Ischemic Heart Disease. Data of Follow-up for Two Years.].	APOB PPARG	9.32e-05	5	107	2	15699916
Pubmed	Clinical exome sequencing in early-onset generalized dystonia and large-scale resequencing follow-up.	ADCY5 ANO3	9.32e-05	5	107	2	27666935
Pubmed	Small CTD phosphatases function in silencing neuronal gene expression.	GRIN2A SCN2A	9.32e-05	5	107	2	15681389
Pubmed	Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.	SCN2A SCN3A	9.32e-05	5	107	2	24337656
Pubmed	mDia1/3-dependent actin polymerization spatiotemporally controls LAT phosphorylation by Zap70 at the immune synapse.	DIAPH1 DIAPH2	9.32e-05	5	107	2	31911947
Pubmed	RhoD activated by fibroblast growth factor induces cytoneme-like cellular protrusions through mDia3C.	DIAPH1 DIAPH2	9.32e-05	5	107	2	23034183
Pubmed	Radiogenomics of clear cell renal cell carcinoma: associations between CT imaging features and mutations.	SETD2 PBRM1	9.32e-05	5	107	2	24029645
Pubmed	Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.	SCN2A SCN3A	9.32e-05	5	107	2	17724025
Pubmed	Neuronal surface P antigen (NSPA) modulates postsynaptic NMDAR stability through ubiquitination of tyrosine phosphatase PTPMEG.	GRIN2A ZZEF1	9.32e-05	5	107	2	33158444
Pubmed	Proliferative action of mast-cell tryptase is mediated by PAR2, COX2, prostaglandins, and PPARgamma : Possible relevance to human fibrotic disorders.	PPARG NR1I2	9.32e-05	5	107	2	12397176
Pubmed	Reduced dosage of β-catenin provides significant rescue of cardiac outflow tract anomalies in a Tbx1 conditional null mouse model of 22q11.2 deletion syndrome.	SEMA3C MYL3 TBX5	1.08e-04	30	107	3	28346476
Pubmed	EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration.	DIAPH1 DIAPH2	1.40e-04	6	107	2	15311282
Pubmed	A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.	SCN2A SCN3A	1.40e-04	6	107	2	23652591
Pubmed	Opposing actions of heat shock protein 90 and 70 regulate nicotinamide adenine dinucleotide phosphate oxidase stability and reactive oxygen species production.	NOX5 HSP90AB1	1.40e-04	6	107	2	23023377
Pubmed	Specificity of interactions between mDia isoforms and Rho proteins.	DIAPH1 DIAPH2	1.40e-04	6	107	2	18829452
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	BCOR IQGAP1 SETD2 ZNF644 CDK11B NIPBL GOLGA4 WDR62 CDC23 HSP90AB1	1.42e-04	774	107	10	15302935
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CMTR1 TBC1D30 ARHGAP23 LAPTM5 PLCD3 SETD2 DHTKD1 KLHL18	1.47e-04	493	107	8	15368895
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	USP9X PPP1R13L IQGAP1 PBRM1 CDK11B NIPBL CDC23 HSP90AB1	1.69e-04	503	107	8	16964243
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SEMA3C DENND4A ARHGAP23 ZZEF1 PLCD3 SLC30A5 BUB1 DIAPH2 CMTR2	1.86e-04	650	107	9	38777146
Pubmed	The genetics of obesity.	PPARG JAK1	1.95e-04	7	107	2	9229117
Pubmed	Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation.	MYL3 PBRM1 TBX5	2.04e-04	37	107	3	24335282
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	USP34 USP9X SETD2 ZNF644 MKLN1 CDC23	2.45e-04	282	107	6	23667531
Pubmed	Cooperative interaction of Nkx2.5 and Mef2c transcription factors during heart development.	MYL3 TBX5	2.59e-04	8	107	2	19035347
Pubmed	Update on the Kelch-like (KLHL) gene family.	KLHL10 KLHL9 KLHL18	2.77e-04	41	107	3	23676014
Pubmed	Genomic analysis of mouse retinal development.	CFAP251 DUSP8 SLC35B2 PLCD3 NRXN2 CCDC47 RABGAP1L PIP4K2C ROBO3 KLHL18 HSP90AB1	2.78e-04	1006	107	11	15226823
Pubmed	Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy.	SLC25A24 ATP6V1A DERA PIP4K2C DHTKD1 HSP90AB1	2.96e-04	292	107	6	35545034
Pubmed	International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.	SCN2A SCN3A	3.33e-04	9	107	2	16382098
Pubmed	Genome-wide association study identifies three susceptibility loci for laryngeal squamous cell carcinoma in the Chinese population.	GRIN2A TBX5	3.33e-04	9	107	2	25194280
Pubmed	New quantitative trait loci that contribute to cholesterol gallstone formation detected in an intercross of CAST/Ei and 129S1/SvImJ inbred mice.	PPARG NR1I2	3.33e-04	9	107	2	12837957
Pubmed	Cross-repression, a functional consequence of the physical interaction of non-liganded nuclear receptors and POU domain transcription factors.	PPARG NR1I2	3.33e-04	9	107	2	11891224
Pubmed	The heat shock protein 90-CDC37 chaperone complex is required for signaling by types I and II interferons.	JAK1 HSP90AB1	3.33e-04	9	107	2	16280321
Pubmed	Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.	SCN2A SCN3A	3.33e-04	9	107	2	15746173
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	KIF18A USP9X DUSP8 BCOR PPP1R13L PTPRN CCDC47 DUSP10 GOLGA4 TTC33 HSP90AB1	3.95e-04	1049	107	11	27880917
Pubmed	Analysis of cDNA sequences from mouse testis.	BUB1 GPATCH11	4.15e-04	10	107	2	8000140
Cytoband	16p13.11	NPIPA1 NPIPA5 NPIPA3	2.11e-05	23	107	3	16p13.11
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN2A SCN3A	5.38e-04	9	71	2	1203
GeneFamily	Kelch like\|BTB domain containing	KLHL10 KLHL9 KLHL18	5.97e-04	42	71	3	617
GeneFamily	MAP kinase phosphatases	DUSP8 DUSP10	8.17e-04	11	71	2	895
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	KLHL10 KLHL9 KBTBD12 KLHL18	1.91e-03	134	71	4	861
GeneFamily	G-patch domain containing\|Minor histocompatibility antigens	CMTR1 GPATCH11	3.34e-03	22	71	2	579
GeneFamily	Solute carriers	SLC25A24 SLC6A17 SLC35B2 SLC30A5 SLC25A2 SLC19A1	4.54e-03	395	71	6	752
ToppCell	Ionocyte-iono-1\|World / Class top	ATP6V1A DENND4A CMTR1 DUSP8 PPARG ADCY5 IQGAP1 DUSP10	7.97e-09	169	107	8	4b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCell	Ionocyte-iono-2\|World / Class top	ATP6V1A FAM184A ATP7A PPARG ADCY5 IQGAP1 SCN3A LIX1	9.58e-09	173	107	8	e5ec28ccc5e048fd98de4c876e5c53b866b66228
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ATP6V1A SEMA3C PPARG FREM1 SCN2A KBTBD12 PRKG1	3.91e-07	190	107	7	b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	IQGAP1 JAK1 SETD2 DIAPH1 NIPBL GOLGA4 HSP90AB1	5.53e-07	200	107	7	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SEMA3C KCNB2 ADCY5 PRKG1 ANO3 TBX5	2.85e-06	164	107	6	e3983f655cdba308fb192182829f17bef99ce0ba
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GRIN2A ADGRV1 DNAH12 PTPRN TTC29 SCN3A	2.96e-06	165	107	6	4b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3C ATP7A DUSP8 PPARG FOXF1 TBX5	3.06e-06	166	107	6	aa2df07eff323ded751ced8938af08223d7f2029
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3C ATP7A DUSP8 PPARG FOXF1 TBX5	3.06e-06	166	107	6	695298a94d62b8adab083900003ec636fbaae5d9
ToppCell	Ionocyte\|World / Class top	ATP6V1A ATP7A PPARG ADCY5 IQGAP1 LIX1	3.51e-06	170	107	6	d2e592f2a679e6a8d32f2b752d9a3c493e50ced4
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FAM184A ADGRV1 KCNB2 PTPRN SCN2A SCN3A	4.01e-06	174	107	6	a62531ebf16b32b249168dca11b870f63a8aa81c
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SEMA3C KCNB2 ADCY5 PRKG1 ANO3 TBX5	4.43e-06	177	107	6	b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ATP6V1A SEMA3C PPARG FREM1 KBTBD12 PRKG1	4.72e-06	179	107	6	e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A17 APOB ADGRV1 FREM1 SCN2A ANO3	5.53e-06	184	107	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	P07-Epithelial-airway_epithelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CFAP251 ACOX2 FHAD1 DNAH12 TTLL6 TTC29	5.53e-06	184	107	6	a5e7af3392e9d6ddad0397f1eeb6b91ed1107cc2
ToppCell	P07-Epithelial-airway_epithelial_cell-club_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CFAP251 ACOX2 FHAD1 DNAH12 TTLL6 TTC29	5.53e-06	184	107	6	ab469b9e06212462cbe2e4db8775c6778db855e6
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A17 APOB ADGRV1 FREM1 SCN2A ANO3	5.53e-06	184	107	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A17 APOB ADGRV1 FREM1 SCN2A ANO3	5.53e-06	184	107	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	USP34 DENND4A USP9X ZNF644 KLHL18 NIPBL	6.26e-06	188	107	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Striatum / BrainAtlas - Mouse McCarroll V32	PDE2A GRIN2A ADCY5 SCN2A SCN3A ANO3	6.26e-06	188	107	6	e34ea7014c5a059a7db38f78bd903cf02616ddd3
ToppCell	PND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 ACOX2 FHAD1 DNAH12 TTLL6 TTC29	6.45e-06	189	107	6	057d7a03fdbe779122b203619a6f947f49b84d28
ToppCell	PND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 ACOX2 FHAD1 DNAH12 TTLL6 TTC29	6.45e-06	189	107	6	9f57a131902d23494bf389baf6e6e2d99f88b2c8
ToppCell	PND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 ACOX2 FHAD1 DNAH12 TTLL6 TTC29	6.45e-06	189	107	6	e443b02502edaefa94567a9e8af5756e8e11ff30
ToppCell	15-Trachea-Epithelial-Neuroendocrine\|Trachea / Age, Tissue, Lineage and Cell class	SLC6A17 KCNB2 FREM1 PTPRN SCN2A SCN3A	6.85e-06	191	107	6	76311fa5f3ae9bb27cf04387a8c92300f2888c28
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3C PPARG FREM1 SCN2A DIAPH1 KBTBD12	7.06e-06	192	107	6	f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP23 GRIN2A ADCY5 NRXN2 SCN3A FOXF1	7.27e-06	193	107	6	2483bb7f398e4fa0ef09c8bd584ed25703853f03
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC6A17 GRIN2A KCNB2 SCN2A SCN3A ANO3	7.71e-06	195	107	6	ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCell	Macrophages-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	CWF19L2 SEMA3C GRIN2A PPARG LAPTM5 GPATCH11	7.71e-06	195	107	6	e48bf57e6da23fbb4637a02387155f825455c49f
ToppCell	Striatum-Neuronal-Excitatory\|Striatum / BrainAtlas - Mouse McCarroll V32	PDE2A GRIN2A ADCY5 SCN2A SCN3A ANO3	7.94e-06	196	107	6	67400193ba469cf4d939e94f5ed94995e384bc07
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP251 FHAD1 DNAH12 TTC29 BUB1 WDR62	8.41e-06	198	107	6	f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GRIN2A KCNB2 ADCY5 PRKG1 FOXF1 TBX5	8.41e-06	198	107	6	c12e7511628db819a52959bb68580e27c00c2e41
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SEMA3C ADCY5 DIAPH2 PRKG1 TBX5 HSP90AB1	8.91e-06	200	107	6	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3C APOB FREM1 SCN2A SCN3A	2.74e-05	146	107	5	e887e9de895fd453faa703997ef372cc6410fc49
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KCNB2 ADCY5 PRKG1 ANO3 TBX5	3.42e-05	153	107	5	1524557514668f515ac1bbe847611f564b265b42
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADGRV1 KCNB2 PTPRN TTLL6 SCN3A	3.64e-05	155	107	5	498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ATP6V1A SEMA3C SCN2A KBTBD12 PRKG1	4.24e-05	160	107	5	1e210e526ea4d84fc58a798a26c0929bcb69fd89
ToppCell	IPF-Epithelial-PNEC\|Epithelial / Disease state, Lineage and Cell class	SLC6A17 KCNB2 PTPRN SCN2A SCN3A	4.50e-05	162	107	5	865d0e215d54fb1412f00cf0649c71c2f1878e57
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATP6V1A FREM1 SCN2A SCN3A PRKG1	4.91e-05	165	107	5	9bd332e5ede759a00a47728ea5558c215efdd77a
ToppCell	367C-Fibroblasts-Fibroblast-F\|367C / Donor, Lineage, Cell class and subclass (all cells)	SEMA3C KCNB2 PLCD3 KBTBD12 NPIPA3	5.05e-05	166	107	5	2887f4f0c218cbcbcc82eef27aa4ee714b35cddb
ToppCell	367C-Fibroblasts-Fibroblast-F-\|367C / Donor, Lineage, Cell class and subclass (all cells)	SEMA3C KCNB2 PLCD3 KBTBD12 NPIPA3	5.05e-05	166	107	5	1cc291a04f4144abba4aca7badeb7776db05d903
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 ACOX2 FHAD1 DNAH12 TTLL6	5.35e-05	168	107	5	fa7c0303918cea04e3f4c4f3cb079be19004d214
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 ACOX2 FHAD1 DNAH12 TTLL6	5.35e-05	168	107	5	7edcab103c69e928d5c19a0d218ffb3ae32f9e70
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 FHAD1 DNAH12 PTPRN TTLL6	5.81e-05	171	107	5	4f2a83d8091f1fd29542d2e5add57fd482e921b5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ATP6V1A SEMA3C FREM1 KBTBD12 PRKG1	6.49e-05	175	107	5	77c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATP6V1A SEMA3C FREM1 KBTBD12 PRKG1	6.49e-05	175	107	5	98947a226b5a2ac7091ff9d34243ea7736add973
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP251 PLCD3 FHAD1 DNAH12 GPATCH11	6.66e-05	176	107	5	87de432c680b80555342afac864599bbc002c040
ToppCell	COVID-19-kidney-vSMC/Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC6A17 GRIN2A ADCY5 SCN3A PRKG1	7.22e-05	179	107	5	111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCell	ASK454-Epithelial-Ciliated\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	CFAP251 FHAD1 DNAH12 CYP4X1 ANO3	7.22e-05	179	107	5	f21919ef9d3d984e2925ef3d24f89e20fe265dcd
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NOX5 FHAD1 DNAH12 TTLL6 TTC29	7.22e-05	179	107	5	5e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF18A SCN2A SCN3A BUB1 WDR62	7.41e-05	180	107	5	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FREM1 SCN2A SCN3A PRKG1 TBX5	7.41e-05	180	107	5	788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCell	P03-Epithelial-airway_epithelial_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CFAP251 ACOX2 FHAD1 DNAH12 TTC29	7.61e-05	181	107	5	1ea21d860d4d7abab3e21e130a16d044006656ee
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC6A17 DNAH12 PTPRN TTC29 SCN3A	7.61e-05	181	107	5	2392af8c7f040c23a7d416c2e37419954970c8f4
ToppCell	P03-Epithelial-airway_epithelial_cell-club_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CFAP251 ACOX2 FHAD1 DNAH12 TTC29	7.61e-05	181	107	5	60a91587c59029a34e7bec1255083337fe21b72a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ATP6V1A SEMA3C PPARG FREM1 KBTBD12	7.61e-05	181	107	5	30729f0364f719c044712a51453e22dc2c1a232b
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DENND4A LAPTM5 SCN3A DUSP10 HSP90AB1	7.61e-05	181	107	5	d66838fca0429cad2079cd8d92a5cd33eb0d3522
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	SLC6A17 KCNB2 PTPRN SCN2A SCN3A	7.81e-05	182	107	5	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	cellseq-Epithelial-Epithelial_Neuro-Secretory-Ionocyte\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ATP6V1A SEMA3C ATP7A ADCY5 GPT2	7.81e-05	182	107	5	6e7dac78dc030f74e546b9f6db07556e9bb13ac2
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GRIN2A ADGRV1 KCNB2 ADCY5 LIX1	7.81e-05	182	107	5	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	cellseq-Epithelial-Epithelial_Neuro-Secretory-Ionocyte-Ionocyte\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ATP6V1A SEMA3C ATP7A ADCY5 GPT2	7.81e-05	182	107	5	cd972d30519db706477c6b0c901165b81b74abed
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SEMA3C DUSP8 KCNB2 ADCY5 FOXF1	8.01e-05	183	107	5	a1d4f25e13f5b9e92a9ca0a804a7bed5df8fb2fe
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IQGAP1 SETD2 DIAPH1 NIPBL GOLGA4	8.22e-05	184	107	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	E18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 ACOX2 FHAD1 DNAH12 TTC29	8.22e-05	184	107	5	797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCell	E18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 ACOX2 FHAD1 DNAH12 TTC29	8.22e-05	184	107	5	77d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCell	Ciliated_cells-A-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	CFAP251 FHAD1 DNAH12 TTLL6 TTC29	8.43e-05	185	107	5	d77ca57b02125a3a57a37f4aed20c89803b7d551
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATP6V1A FREM1 SCN2A SCN3A PRKG1	8.43e-05	185	107	5	3d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	OR5A2 ADGRV1 FAM186A SCN2A DIAPH2	8.65e-05	186	107	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SLC6A17 KCNB2 PTPRN SCN2A SCN3A	8.65e-05	186	107	5	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	367C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	APOB PLA2G6 NPIPA3 CMTR2	8.84e-05	97	107	4	a1279377bf0ee5662db8b9303f5f1fd418dee6df
ToppCell	367C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	APOB PLA2G6 NPIPA3 CMTR2	8.84e-05	97	107	4	12cbd03b33e76e5e471bbee2a9c11f27e8b21123
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC6A17 KCNB2 ADCY5 PTPRN SCN3A	9.09e-05	188	107	5	1f912ea015f50570e848259d948a0ba682d64bb4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA3C PPARG FREM1 DIAPH1 KBTBD12	9.09e-05	188	107	5	e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	USP34 KCNB2 SCN2A SCN3A CYP4X1	9.09e-05	188	107	5	b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SLC6A17 KCNB2 PTPRN SCN2A SCN3A	9.09e-05	188	107	5	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 ACOX2 FHAD1 DNAH12 TTLL6	9.32e-05	189	107	5	b55de812043b670cbde810d7d42f45909b6d66ef
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 FHAD1 DNAH12 TTLL6 TTC29	9.32e-05	189	107	5	02c6128a9ab5818e0881dcadafdad5f08b9a67cf
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 FHAD1 DNAH12 TTLL6 TTC29	9.32e-05	189	107	5	164ea92ff6a1aa2ead1c9b8f64f99a9d65437232
ToppCell	PND10-Epithelial-Epithelial_Airway\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 FHAD1 DNAH12 TTLL6 TTC29	9.32e-05	189	107	5	407d8a59969d83f014600aae1a55092283a13970
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATP6V1A SEMA3C ADCY5 FHAD1 DNAH12	9.32e-05	189	107	5	cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCell	facs-Skin-nan-18m-Mesenchymal-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM184A SLC6A17 NRXN2 PRKG1 TBX5	9.32e-05	189	107	5	29287525120be2953b76881ba3cfc4379c265e7a
ToppCell	facs-Skin-nan-18m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM184A SLC6A17 NRXN2 PRKG1 TBX5	9.32e-05	189	107	5	7150dad9a92a715487c2d8130fa01b752ea69663
ToppCell	facs-Skin-nan-18m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM184A SLC6A17 NRXN2 PRKG1 TBX5	9.32e-05	189	107	5	6e4c0effd5192fd00052abc048fdb87a74fb6554
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 FHAD1 DNAH12 TTLL6 TTC29	9.32e-05	189	107	5	a85099bd598a27ee64ee0664d051d89fa8d62fc9
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 ACOX2 FHAD1 DNAH12 TTLL6	9.32e-05	189	107	5	4e83e49d1265ffe507fdb72924c77c4d1c73f0bd
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC6A17 KCNB2 PTPRN SCN2A SCN3A	9.56e-05	190	107	5	40d8b3403f4e38436b961cd3a2e69826cbae3042
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC6A17 KCNB2 PTPRN SCN2A SCN3A	9.56e-05	190	107	5	f6cbf6d292f488ada5f7581e1dceba6198b933d1
ToppCell	Mesenchymal-airway_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	SEMA3C CYP27C1 ADCY5 FOXF1 TBX5	9.56e-05	190	107	5	645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC6A17 KCNB2 PTPRN SCN2A SCN3A	9.56e-05	190	107	5	a9a705455019e28d655636de73b07540798f82e6
ToppCell	PND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 ACOX2 FHAD1 DNAH12 TTLL6	9.56e-05	190	107	5	088e3f39a1e5e11354d6e7458e8e6a39f14936b3
ToppCell	PND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 ACOX2 FHAD1 DNAH12 TTLL6	9.56e-05	190	107	5	35248a8be476ea8d06d67c3d98a25be1f7c150b7
ToppCell	E18.5-Epithelial-Epithelial_Airway\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 FHAD1 DNAH12 TTLL6 TTC29	9.56e-05	190	107	5	5c012935ea5e35a2d0d08ea7dc04ffbe3c2a10ac
ToppCell	PND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 ACOX2 FHAD1 DNAH12 TTLL6	9.56e-05	190	107	5	5f5206f9e725070d865f4c891ff08bb750e58582
ToppCell	E18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 FHAD1 DNAH12 TTLL6 TTC29	9.80e-05	191	107	5	acd844b477a069b2dcf07b2998e1b5c87dc0eb94
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 FHAD1 DNAH12 TTLL6 TTC29	9.80e-05	191	107	5	bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 FHAD1 DNAH12 TTLL6 TTC29	9.80e-05	191	107	5	6880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCell	E18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 FHAD1 DNAH12 TTLL6 TTC29	9.80e-05	191	107	5	e8d56e9f43943e9cc4dce83f2c234f19c2dd487d
ToppCell	E18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 FHAD1 DNAH12 TTLL6 TTC29	9.80e-05	191	107	5	52e8d7dfaf1ebb6df8bf3a1f4546af59faa67657
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 FHAD1 DNAH12 TTLL6 TTC29	9.80e-05	191	107	5	1e21de183a9c09cfb6aad3f9b948087fb6bad061
ToppCell	PND07-Epithelial-Epithelial_Airway\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 FHAD1 DNAH12 TTLL6 TTC29	9.80e-05	191	107	5	b55500eb416f4f339031acad16b2737e5b891d8e
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP251 FHAD1 DNAH12 TTLL6 TTC29	9.80e-05	191	107	5	8688708c9183ebcb200596501dc30cc12073f151
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP34 APOB IQGAP1 DIAPH1 GOLGA4	9.80e-05	191	107	5	09db184cb90fe282a14474d7217068c58092c6f8
Drug	2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate	NR1I2 SCN2A SCN3A	4.81e-06	8	102	3	ctd:C489827
Drug	benzoxazinone analogue	APOB PPARG ACOX2	4.81e-06	8	102	3	CID000468715
Disease	autosomal dominant auditory neuropathy 1 (implicated_via_orthology)	DIAPH1 DIAPH2	3.54e-05	3	102	2	DOID:0060690 (implicated_via_orthology)
Disease	colorectal cancer (is_implicated_in)	GRIN2A BCOR JAK1 SETD2 BUB1	6.47e-05	121	102	5	DOID:9256 (is_implicated_in)
Disease	Intellectual Disability	SETD2 NRXN2 CCDC47 SURF1 SCN3A DIAPH1 GPT2 WDR62	1.65e-04	447	102	8	C3714756
Disease	proliferative diabetic retinopathy (is_implicated_in)	PPARG BCOR	1.76e-04	6	102	2	DOID:13207 (is_implicated_in)
Disease	Seizure, Febrile, Simple	SCN2A ANO3	2.46e-04	7	102	2	C0149886
Disease	Seizure, Febrile, Complex	SCN2A ANO3	2.46e-04	7	102	2	C0751057
Disease	pulse pressure measurement	USP34 CWF19L2 PPARG ADCY5 PLCD3 PBRM1 TTLL6 MKLN1 KCNN4 CDK11B ROBO3 CMTR2 GOLGA4 TBX5	3.10e-04	1392	102	14	EFO_0005763
Disease	Embryonal Rhabdomyosarcoma	BCOR SETD2	3.27e-04	8	102	2	C0206656
Disease	pancreatitis (biomarker_via_orthology)	DUSP10 HSP90AB1 HSP90AB3P	3.35e-04	39	102	3	DOID:4989 (biomarker_via_orthology)
Disease	body weight	MC4R ADGRV1 KCNB2 ZZEF1 ADCY5 SETD2 NR1I2 DNAH12 PTPRN RABGAP1L TTC29 PLA2G6 NIPBL	4.08e-04	1261	102	13	EFO_0004338
Disease	Febrile Convulsions	SCN2A ANO3	4.19e-04	9	102	2	C0009952
Disease	Generalized Epilepsy with Febrile Seizures Plus	ADGRV1 SCN2A	4.19e-04	9	102	2	C3502809
Disease	liver cancer (is_marker_for)	SETD2 GPT2	4.19e-04	9	102	2	DOID:3571 (is_marker_for)
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN2A SCN3A	5.23e-04	10	102	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN2A SCN3A	5.23e-04	10	102	2	DOID:0080422 (implicated_via_orthology)
Disease	polycystic ovary syndrome, type 2 diabetes mellitus	MC4R ADCY5	5.23e-04	10	102	2	EFO_0000660, MONDO_0005148
Disease	cholesteryl ester 20:3 measurement	FAM184A NPIPA1 APOB	6.58e-04	49	102	3	EFO_0010347
Disease	obsolete_red blood cell distribution width	SEMA3C CFAP251 ARHGAP23 APOB PPARG IQGAP1 DERA PBRM1 SLC19A1 RABGAP1L KCNN4 PLA2G6 HSP90AB1	7.56e-04	1347	102	13	EFO_0005192
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN2A SCN3A	7.64e-04	12	102	2	DOID:0060170 (implicated_via_orthology)
Disease	age at first birth measurement	KIF18A FREM1 SCN2A DIAPH1	8.13e-04	120	102	4	EFO_0009101
Disease	C-reactive protein measurement	USP34 CWF19L2 CFAP251 MC4R APOB KCNB2 ZZEF1 ADCY5 JAK1 NR1I2 ZNF644 PLA2G6	9.38e-04	1206	102	12	EFO_0004458
Disease	red blood cell density measurement	SEMA3C DENND4A MYL3 ADGRV1 PPARG PBRM1 SLC19A1 KCNN4 PLA2G6 TTC33	9.50e-04	880	102	10	EFO_0007978
Disease	MMR-related febrile seizures	SCN2A ANO3	1.21e-03	15	102	2	EFO_0006519
Disease	amenorrhea, response to antineoplastic agent	APOB DERA	1.21e-03	15	102	2	EFO_0010269, GO_0097327
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	JAK1 SETD2 SLC19A1	1.25e-03	61	102	3	C1961102
Disease	Barrett Epithelium	PPARG NR1I2	1.38e-03	16	102	2	C1258085
Disease	response to acetylsalicylate	SETD2 KLHL18	1.38e-03	16	102	2	GO_1903492
Disease	Barrett Esophagus	PPARG NR1I2	1.38e-03	16	102	2	C0004763
Disease	primary autosomal recessive microcephaly (is_implicated_in)	BUB1 WDR62	1.38e-03	16	102	2	DOID:0070296 (is_implicated_in)
Disease	body mass index, type 2 diabetes mellitus	PPARG ADCY5	1.38e-03	16	102	2	EFO_0004340, MONDO_0005148
Disease	body fat percentage, type 2 diabetes mellitus	PPARG ADCY5	1.56e-03	17	102	2	EFO_0007800, MONDO_0005148
Disease	physical activity measurement	CWF19L2 PDSS2 GRIN2A RABGAP1L SCN2A	1.64e-03	245	102	5	EFO_0008002
Disease	Febrile seizure (within the age range of 3 months to 6 years)	SCN2A ANO3	1.75e-03	18	102	2	HP_0002373
Disease	Congenital hernia of foramen of Morgagni	FREM1 FOXF1	1.95e-03	19	102	2	C0265699
Disease	Congenital hernia of foramen of Bochdalek	FREM1 FOXF1	1.95e-03	19	102	2	C0265700
Disease	intrahepatic cholangiocarcinoma (is_marker_for)	PBRM1 HSP90AB1	1.95e-03	19	102	2	DOID:4928 (is_marker_for)
Disease	Congenital diaphragmatic hernia	FREM1 FOXF1	2.38e-03	21	102	2	C0235833
Disease	bone density, lean body mass	MC4R HSP90AB3P	2.38e-03	21	102	2	EFO_0003923, EFO_0004995
Disease	epilepsy (implicated_via_orthology)	GRIN2A SCN2A SCN3A PRKG1	2.51e-03	163	102	4	DOID:1826 (implicated_via_orthology)
Disease	anxiety disorder (implicated_via_orthology)	SCN2A SCN3A	2.61e-03	22	102	2	DOID:2030 (implicated_via_orthology)
Disease	memory performance	DENND4A TBC1D30 PPARG PBRM1 DIAPH2 PRKG1	3.01e-03	409	102	6	EFO_0004874
Disease	congenital diaphragmatic hernia (biomarker_via_orthology)	ATP7A FREM1	3.11e-03	24	102	2	DOID:3827 (biomarker_via_orthology)
Disease	Dyslipidemias	APOB PPARG	3.11e-03	24	102	2	C0242339
Disease	Dyslipoproteinemias	APOB PPARG	3.11e-03	24	102	2	C0598784
Disease	reticulocyte count	USP34 KLHL10 DENND4A USP9X PPARG PTPRN SLC19A1 KCNN4 PLA2G6 HSP90AB1	3.34e-03	1045	102	10	EFO_0007986

Protein segments in the cluster

Peptide	Gene	Start	Entry
QAHQMAPDMFYCMKL	GPT2	456	Q8TD30
KMSMYEASAHVPLLM	ARSK	326	Q6UWY0
LHALSTGMKAMMSEF	ACOX2	386	Q99424
MGHEYMEMKNTSAAI	CDC23	371	Q9UJX2
EALELMFSMFKTSMY	CYP27C1	256	Q4G0S4
LKPSMQHMFMKFYSA	BUB1	841	O43683
SFAMRMLYMIEQVHD	BUB1	896	O43683
IAIAYIMKTMGMSSD	DUSP8	256	Q13202
IMKTMGMSSDDAYRF	DUSP8	261	Q13202
IVEKALYDYMGSEMM	ADAM18	191	Q9Y3Q7
ARYSMFAAKLLTHMM	ADGRV1	5931	Q8WXG9
MFTMFEHCSINLMYL	CMTR2	276	Q8IYT2
MNYVEHDLKSLMETM	CDK11B	516	P21127
MKLMDQMKYINEHSF	ADCY5	1156	O95622
YNKLRMMHSNMETLY	DIAPH1	1101	O60610
MMHSNMETLYKELGE	DIAPH1	1106	O60610
ESMMGFFHELLKMSA	DHTKD1	196	Q96HY7
LSTMHNNMMKLYENL	DIAPH2	961	O60879
VQNMAFQYGKHMAMS	PDSS2	276	Q86YH6
YSGRTIMKMTHSELM	BCOR	1561	Q6W2J9
GHSMDYSQEMHLKMS	FAM184A	31	Q8NB25
MNLHGLMDEYLEMVL	ANO3	746	Q9BYT9
GNGIMAMAMTHDAKY	CFAP251	346	Q8TBY9
GLMIYMMVMDHHFAT	ATP7A	666	Q04656
KFMGVQMETFMLHYQ	IQGAP1	1606	P46940
SHQKFYNMMTKTQMF	DENND4A	611	Q7Z401
GMAVLAISHYAMMKK	JAK1	191	P23458
AISHYAMMKKMQLPE	JAK1	196	P23458
GKLDMKEIHTYMEMF	NPIPA1	171	Q9UND3
ELHMYMTSALGKNDM	NOX5	671	Q96PH1
LRDNSTMGYMMAKKH	HSP90AB1	611	P08238
NMDISTGHMILAYME	PTPRN	686	Q16849
SHMMANKYQDIDSMV	PBRM1	711	Q86U86
EIMNMMGVYADRKHF	MAGEB18	221	Q96M61
NSMVDISKMHMILYD	KCNN4	366	O15554
TKMMDFETFLPMLQH	MYL3	106	P08590
VLFEYMMGRETKTMA	GOLGA4	2181	Q13439
DNSTMGYMMAKKHLE	HSP90AB3P	486	Q58FF7
GVMYLTMLHLYKCMD	KIF18A	131	Q8NI77
MMRTGLIKHTEYMEF	PRKG1	201	Q13976
AYLMKHTRMTMTDAY	DUSP10	421	Q9Y6W6
GMMDTKMVHFLTHYA	CCDC47	311	Q96A33
KMDSHLHMPMYFFLS	OR5A2	51	Q8NGI9
KFMLSGYNFSVMENM	PCDH1	611	Q08174
MMYHMKVSDDEYTKL	PDE2A	571	O00408
TNMSMKKQYHMVYEC	CWF19L2	756	Q2TBE0
MELLKTGMRLTYMHD	FREM1	1226	Q5H8C1
GFIHMKAVAGMKMSY	NIPBL	2351	Q6KC79
DGSMYMKIMLPNAMH	NRXN2	736	Q9P2S2
MDMIKMGVSHDTDFL	DNAH12	1176	Q6ZR08
HRAMMASASDYFKAM	KLHL9	66	Q9P2J3
PHMADMSTYMFKGII	NR1I2	241	O75469
GKLDMKEIHTYMEMF	NPIPA3	171	F8WFD2
HFQLMQGKMADMYTR	IVD	321	P26440
HYMLESNMGKTMLEF	LIX1	146	Q8N485
MHLLDMESMGKSYDG	RABGAP1L	346	Q5R372
DMMGSYAEMKFDHTN	APOB	1741	P04114
LMNIKNMSGHVSMKY	FHAD1	1256	B1AJZ9
SHMKLNMAEEEDYMS	GPATCH11	21	Q8N954
LALMHAEYFMNNVKM	KLHL10	231	Q6JEL2
PYFHAMFTNDMMECK	KLHL18	61	O94889
NFYRTGKLHMMEEMC	KCNB2	101	Q92953
AYIEVMAHSVKMMLD	CYP4X1	151	Q8N118
NMLKLGASVNMYMFH	GLB1L	291	Q6UWU2
FFTMLALMASLYVHM	MC4R	201	P32245
HMMLSRLDDYGKKVM	FAM186A	2191	A6NE01
NVYKASMIAMMAGSD	DERA	201	Q9Y315
DFLDMNFQSLAMKHM	PPP1R13L	11	Q8WUF5
MYNSVSQKLMAKMGF	CMTR1	86	Q8N1G2
EDSYMLVMRNMFSHR	PIP4K2C	196	Q8TBX8
VFSVCQKYMMDHMDA	KBTBD12	116	Q3ZCT8
QKYMMDHMDASNCLG	KBTBD12	121	Q3ZCT8
TLMLQEHRMFMGEAY	MROH5	71	Q6ZUA9
GKLDMKEIHTYMEMF	NPIPA7	171	E9PJI5
GKLDMKEIHTYMEMF	NPIPA8	171	P0DM63
LKPMYSMMNGLGFNH	FOXF1	151	Q12946
MGEVFDHMMKRMSYR	USP9X	1926	Q93008
KDIMGAFSHSEMQMI	SEMA3C	691	Q99985
DMELHRMSRMQSKEY	TBX5	241	Q99593
MEVPTYLNFKSMNHM	LAPTM5	156	Q13571
QMCMDSEKHMIYTFG	MKLN1	391	Q9UL63
GKLDMKEIHTYMEMF	NPIPA5	171	E9PKD4
DKSPFVIYDMNSLMM	PPARG	271	P37231
FDHSKELYMMPRTMV	SURF1	126	Q15526
VLNTLFMAMEHYPMT	SCN3A	771	Q9NY46
FMAMEHYPMTEQFSS	SCN3A	776	Q9NY46
LAILHSKSMAYMRGM	PLA2G6	526	O60733
TMYEMEMSGKIAKSH	SLC25A2	136	Q9BXI2
AKDMLYKMLSENFMS	POLR3C	391	Q9BUI4
ALFAYKMSSVQMMFG	SLC35B2	291	Q8TB61
KQHELMTLDGFMMYL	PLCD3	306	Q8N3E9
NMTDMVTHMPDRYKI	ARHGAP23	1071	Q9P227
LMMSHTLKSDAGMYV	ROBO3	221	Q96MS0
VAHMQLMELFYSVTM	SLC19A1	116	P41440
LNTLFMAMEHYPMTE	SCN2A	771	Q99250
NFMKYMMSEELVLGI	TTMP	176	Q5BVD1
KDMTMSFHYISMGDC	RAET1G	176	Q6H3X3
KTVGMLSNMIAFYDM	ATP6V1A	536	P38606
YHAAFNSMMMERMTT	TBC1D30	621	Q9Y2I9
MEMKSYQKINHFPGM	TTLL6	106	Q8N841
HQDKLMSMPVMTVDY	SETD2	756	Q9BYW2
NMKHIVSMGYQHDMV	WDR62	166	O43379
LMYQPQKMDLTMHSA	ZNF644	1216	Q9H582
ELMSMPLMDETKVHY	TTC29	386	Q8NA56
GFHDVLAMTKQMESM	SLC30A5	741	Q8TAD4
PAHMTYILDMFMQLE	ZZEF1	2646	O43149
ERNHMNMTYMAKSSV	ZNF818P	31	Q6ZRF7
HLTTKDYMEMYNVIM	SLC6A17	396	Q9H1V8
MTESFNTLHMMYHEA	USP34	2971	Q70CQ2
QVRMTQHLEGMKDMY	TRIM64C	216	A6NLI5
MMQVHGSKSDKMNIF	SLC25A24	221	Q6NUK1
HGIMMESFMRDDIIY	ZFP69	171	Q49AA0
YEMKSQVLMSLHEMF	TTC33	96	Q6PID6
IMDMVSDKGNLMYSD	GRIN2A	931	Q12879