Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium-dependent phospholipid binding	CPNE8 CPNE6 CPNE9 DYSF CPNE5	4.18e-06	60	80	5	GO:0005544
GeneOntologyMolecularFunction	[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity	HS3ST3B1 HS3ST3A1	1.59e-05	2	80	2	GO:0033872
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DYNC2H1 DNAH1 DNAH11	4.84e-05	18	80	3	GO:0008569
GeneOntologyMolecularFunction	phosphatidylinositol kinase activity	PIKFYVE PIK3C2B PIK3R1	1.51e-04	26	80	3	GO:0052742
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DYNC2H1 DNAH1 DNAH11	1.89e-04	28	80	3	GO:0051959
GeneOntologyMolecularFunction	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity	HS3ST3B1 HS3ST3A1	3.29e-04	7	80	2	GO:0008467
GeneOntologyMolecularFunction	dynein intermediate chain binding	DYNC2H1 DNAH1 DNAH11	4.36e-04	37	80	3	GO:0045505
GeneOntologyMolecularFunction	lipid kinase activity	PIKFYVE PIK3C2B PIK3R1	5.92e-04	41	80	3	GO:0001727
GeneOntologyMolecularFunction	calcium ion binding	TGM2 CPNE6 HMCN2 EFCAB6 CDH23 DYSF ZZEF1 FER1L5 FBN3 CEMIP2	7.98e-04	749	80	10	GO:0005509
GeneOntologyMolecularFunction	1-phosphatidylinositol-3-kinase activity	PIK3C2B PIK3R1	8.52e-04	11	80	2	GO:0016303
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYO9B DYNC2H1 DNAH1 DNAH11	1.30e-03	118	80	4	GO:0003774
GeneOntologyMolecularFunction	phospholipid binding	WDR45 CPNE8 CPNE6 CPNE9 PIK3C2B TLN1 DYSF CPNE5	1.57e-03	548	80	8	GO:0005543
GeneOntologyMolecularFunction	heparan sulfate sulfotransferase activity	HS3ST3B1 HS3ST3A1	1.61e-03	15	80	2	GO:0034483
GeneOntologyBiologicalProcess	monocyte activation involved in immune response	DYSF FER1L5	1.49e-05	2	80	2	GO:0002280
Domain	Copine	CPNE8 CPNE6 CPNE9 CPNE5	3.87e-08	9	80	4	PF07002
Domain	Copine	CPNE8 CPNE6 CPNE9 CPNE5	3.87e-08	9	80	4	IPR010734
Domain	C2	CPNE8 CPNE6 CPNE9 PIK3C2B DYSF CPNE5 FER1L5	1.48e-06	131	80	7	PF00168
Domain	C2	CPNE8 CPNE6 CPNE9 PIK3C2B DYSF CPNE5 FER1L5	1.99e-06	137	80	7	SM00239
Domain	C2	CPNE8 CPNE6 CPNE9 PIK3C2B DYSF CPNE5 FER1L5	2.53e-06	142	80	7	PS50004
Domain	-	CPNE8 CPNE6 CPNE9 PIK3C2B DYSF CPNE5 FER1L5	3.33e-06	148	80	7	2.60.40.150
Domain	C2_dom	CPNE8 CPNE6 CPNE9 PIK3C2B DYSF CPNE5 FER1L5	6.57e-06	164	80	7	IPR000008
Domain	-	TLN1 TLN2	1.81e-05	2	80	2	1.20.1420.10
Domain	Talin_middle	TLN1 TLN2	1.81e-05	2	80	2	PF09141
Domain	VBS	TLN1 TLN2	1.81e-05	2	80	2	PF08913
Domain	Vinculin-bd_dom	TLN1 TLN2	1.81e-05	2	80	2	IPR015009
Domain	Talin_cent	TLN1 TLN2	1.81e-05	2	80	2	IPR015224
Domain	Dynein_heavy_chain_D4_dom	DYNC2H1 DNAH1 DNAH11	2.66e-05	14	80	3	IPR024317
Domain	Dynein_HC_stalk	DYNC2H1 DNAH1 DNAH11	2.66e-05	14	80	3	IPR024743
Domain	Dynein_heavy_dom-2	DYNC2H1 DNAH1 DNAH11	2.66e-05	14	80	3	IPR013602
Domain	DHC_N2	DYNC2H1 DNAH1 DNAH11	2.66e-05	14	80	3	PF08393
Domain	MT	DYNC2H1 DNAH1 DNAH11	2.66e-05	14	80	3	PF12777
Domain	AAA_8	DYNC2H1 DNAH1 DNAH11	2.66e-05	14	80	3	PF12780
Domain	ATPase_dyneun-rel_AAA	DYNC2H1 DNAH1 DNAH11	2.66e-05	14	80	3	IPR011704
Domain	AAA_5	DYNC2H1 DNAH1 DNAH11	2.66e-05	14	80	3	PF07728
Domain	VWFA	CPNE8 CPNE6 CPNE9 HMCN2 CPNE5	2.68e-05	82	80	5	PS50234
Domain	VWA	CPNE8 CPNE6 CPNE9 HMCN2 CPNE5	3.01e-05	84	80	5	SM00327
Domain	DHC_fam	DYNC2H1 DNAH1 DNAH11	3.32e-05	15	80	3	IPR026983
Domain	Dynein_heavy_dom	DYNC2H1 DNAH1 DNAH11	3.32e-05	15	80	3	IPR004273
Domain	Dynein_heavy	DYNC2H1 DNAH1 DNAH11	3.32e-05	15	80	3	PF03028
Domain	FerA	DYSF FER1L5	5.42e-05	3	80	2	SM01200
Domain	Talin-1	TLN1 TLN2	5.42e-05	3	80	2	IPR015710
Domain	Ferlin_A-domain	DYSF FER1L5	5.42e-05	3	80	2	IPR012560
Domain	FerA	DYSF FER1L5	5.42e-05	3	80	2	PF08165
Domain	VWF_A	CPNE8 CPNE6 CPNE9 HMCN2 CPNE5	6.63e-05	99	80	5	IPR002035
Domain	I_LWEQ	TLN1 TLN2	1.08e-04	4	80	2	PF01608
Domain	ILWEQ_dom	TLN1 TLN2	1.08e-04	4	80	2	IPR002558
Domain	I_LWEQ	TLN1 TLN2	1.08e-04	4	80	2	PS50945
Domain	DysFC	DYSF FER1L5	1.08e-04	4	80	2	SM00694
Domain	DysFN	DYSF FER1L5	1.08e-04	4	80	2	SM00693
Domain	ILWEQ	TLN1 TLN2	1.08e-04	4	80	2	SM00307
Domain	FERM_f0	TLN1 TLN2	1.08e-04	4	80	2	IPR032425
Domain	FERM_f0	TLN1 TLN2	1.08e-04	4	80	2	PF16511
Domain	ILWEQ	TLN1 TLN2	1.08e-04	4	80	2	PD011820
Domain	Peroxin/Ferlin	DYSF FER1L5	1.08e-04	4	80	2	IPR006614
Domain	-	TLN1 TLN2	1.08e-04	4	80	2	1.20.1410.10
Domain	FerI	DYSF FER1L5	1.80e-04	5	80	2	SM01202
Domain	FerB	DYSF FER1L5	1.80e-04	5	80	2	SM01201
Domain	Ferlin_B-domain	DYSF FER1L5	1.80e-04	5	80	2	IPR012561
Domain	Ferlin_C	DYSF FER1L5	1.80e-04	5	80	2	PF16165
Domain	Ferlin_C	DYSF FER1L5	1.80e-04	5	80	2	IPR032362
Domain	GLYCOSYL_HYDROL_F31_2	MGAM MYORG	1.80e-04	5	80	2	PS00707
Domain	FerIin_dom	DYSF FER1L5	1.80e-04	5	80	2	IPR012968
Domain	FerI	DYSF FER1L5	1.80e-04	5	80	2	PF08151
Domain	FerB	DYSF FER1L5	1.80e-04	5	80	2	PF08150
Domain	Glyco_hydro_31	MGAM MYORG	3.75e-04	7	80	2	IPR000322
Domain	Vinculin/catenin	TLN1 TLN2	3.75e-04	7	80	2	IPR006077
Domain	Glyco_hydro_31	MGAM MYORG	3.75e-04	7	80	2	PF01055
Domain	GLYCOSYL_HYDROL_F31_1	MGAM MYORG	3.75e-04	7	80	2	PS00129
Domain	DHC_N1	DYNC2H1 DNAH11	4.99e-04	8	80	2	PF08385
Domain	Dynein_heavy_dom-1	DYNC2H1 DNAH11	4.99e-04	8	80	2	IPR013594
Domain	IRS_PTB	TLN1 TLN2	1.59e-03	14	80	2	IPR002404
Domain	IRS	TLN1 TLN2	1.59e-03	14	80	2	PF02174
Domain	P-loop_NTPase	SETX MYO9B DYNC2H1 MOV10L1 RNF213 HS3ST3B1 HS3ST3A1 SBNO2 DNAH1 DNAH11	3.27e-03	848	80	10	IPR027417
Domain	-	SETX DYNC2H1 MOV10L1 RNF213 HS3ST3B1 HS3ST3A1 SBNO2 DNAH1 DNAH11	4.54e-03	746	80	9	3.40.50.300
Pubmed	The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans.	CPNE8 CPNE6 CPNE9 CPNE5	3.41e-09	9	81	4	9430674
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	TGM2 SETX COQ8A POGK TONSL SLTM L2HGDH ZZEF1 CEMIP2 SBNO2 SEMA3E	3.31e-07	650	81	11	38777146
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PIKFYVE DNAJC14 TRIO PIK3C2B MYO9B TLN1 TLN2 HERC1 DYSF ZZEF1 MYRF MYORG SBNO2	1.59e-06	1105	81	13	35748872
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	TGM2 DYNC2H1 GLG1 TLN1 MOV10L1 PSMB1 TONSL SLTM ZZEF1 ENO1 DNAH1	2.72e-06	807	81	11	30575818
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	TGM2 CPNE8 CPNE6 CPNE9 ERP44 DERL1 MYO9B TLN1 PSMB1 RNF213 ENO1	4.16e-06	844	81	11	25963833
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DYNC2H1 DNAH1 DNAH11	4.35e-06	14	81	3	9373155
Pubmed	Both Talin-1 and Talin-2 correlate with malignancy potential of the human hepatocellular carcinoma MHCC-97 L cell.	TLN1 TLN2	5.36e-06	2	81	2	26822056
Pubmed	Extracellular rigidity sensing by talin isoform-specific mechanical linkages.	TLN1 TLN2	5.36e-06	2	81	2	26523364
Pubmed	Chromosomal mapping of two members of the human dynein gene family to chromosome regions 7p15 and 11q13 near the deafness loci DFNA 5 and DFNA 11.	DYNC2H1 DNAH11	5.36e-06	2	81	2	9325061
Pubmed	A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entry.	HS3ST3B1 HS3ST3A1	5.36e-06	2	81	2	10520990
Pubmed	Structural analysis of the sulfotransferase (3-o-sulfotransferase isoform 3) involved in the biosynthesis of an entry receptor for herpes simplex virus 1.	HS3ST3B1 HS3ST3A1	5.36e-06	2	81	2	15304505
Pubmed	Genetic variations in genes involved in heparan sulphate biosynthesis are associated with Plasmodium falciparum parasitaemia: a familial study in Burkina Faso.	HS3ST3B1 HS3ST3A1	5.36e-06	2	81	2	22475533
Pubmed	Mutations in DNAH1, which encodes an inner arm heavy chain dynein, lead to male infertility from multiple morphological abnormalities of the sperm flagella.	DNAH1 DNAH11	5.36e-06	2	81	2	24360805
Pubmed	New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2.	TLN1 TLN2	5.36e-06	2	81	2	22306379
Pubmed	High expression of CPNE5 and CPNE9 predicts positive prognosis in multiple myeloma.	CPNE9 CPNE5	5.36e-06	2	81	2	33780365
Pubmed	Regulation of the Na(+), glucose cotransporter by PIKfyve and the serum and glucocorticoid inducible kinase SGK1.	PIKFYVE SGK1	5.36e-06	2	81	2	17570343
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	PIKFYVE SETX PIK3C2B MYO9B DYNC2H1 TONSL NUP42 TOPORS CDC7	9.39e-06	588	81	9	38580884
Pubmed	Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions.	TLN1 TLN2	1.60e-05	3	81	2	12422220
Pubmed	Transglutaminase 2 up-regulation is associated with RANKL/OPG pathway in cultured HPDL cells and THP-1-differentiated macrophages.	TGM2 TNFSF11	1.60e-05	3	81	2	26133738
Pubmed	The SUMO Conjugation Complex Self-Assembles into Nuclear Bodies Independent of SIZ1 and COP1.	SETX TOPORS	1.60e-05	3	81	2	30389781
Pubmed	Mechanotransduction in talin through the interaction of the R8 domain with DLC1.	TLN1 TLN2	1.60e-05	3	81	2	30028837
Pubmed	Assignment of a locus for autosomal dominant idiopathic scoliosis (IS) to human chromosome 17p11.	HS3ST3B1 HS3ST3A1	1.60e-05	3	81	2	12384783
Pubmed	Vinculin and talin: focus on the myocardium.	TLN1 TLN2	1.60e-05	3	81	2	19952892
Pubmed	Talin depletion reveals independence of initial cell spreading from integrin activation and traction.	TLN1 TLN2	1.60e-05	3	81	2	19160486
Pubmed	Talin and vinculin are downregulated in atherosclerotic plaque; Tampere Vascular Study.	TLN1 TLN2	1.60e-05	3	81	2	27816808
Pubmed	PIKfyve-dependent regulation of the Cl- channel ClC-2.	PIKFYVE SGK1	1.60e-05	3	81	2	19232516
Pubmed	Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion.	TLN1 TLN2	1.60e-05	3	81	2	15494027
Pubmed	Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells.	TLN1 TLN2	1.60e-05	3	81	2	18792400
Pubmed	Vinculin controls talin engagement with the actomyosin machinery.	TLN1 TLN2	1.60e-05	3	81	2	26634421
Pubmed	Arginylation-dependent regulation of a proteolytic product of talin is essential for cell-cell adhesion.	TLN1 TLN2	1.60e-05	3	81	2	22665520
Pubmed	RNA-binding protein Musashi2 induced by RANKL is critical for osteoclast survival.	TNFSF11 MSI2	1.60e-05	3	81	2	27441652
Pubmed	Biochemical characterization of copine: a ubiquitous Ca2+-dependent, phospholipid-binding protein.	CPNE8 CPNE9	1.60e-05	3	81	2	11123945
Pubmed	An essential role for talin during alpha(M)beta(2)-mediated phagocytosis.	TLN1 TLN2	1.60e-05	3	81	2	17202407
Pubmed	Loss of mouse cardiomyocyte talin-1 and talin-2 leads to β-1 integrin reduction, costameric instability, and dilated cardiomyopathy.	TLN1 TLN2	1.60e-05	3	81	2	28698364
Pubmed	Insulin activates epithelial sodium channel (ENaC) via phosphoinositide 3-kinase in mammalian taste receptor cells.	SGK1 PIK3R1	1.60e-05	3	81	2	21106690
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZNF462 PIKFYVE ERP44 DYNC2H1 RNF213 UBR3 KAZN MYORG	2.00e-05	493	81	8	15368895
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	PIKFYVE WDR45 CPNE8 PARP16 PIK3R1 VPS13C NUP42 CEMIP2	2.34e-05	504	81	8	34432599
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	SERPINA3 TGM2 HSPA12A DYNC2H1 GLG1 VPS13C TLN1 PSMB1 DYSF CPNE5 CEMIP2	2.35e-05	1016	81	11	19056867
Pubmed	Molecular motors: the driving force behind mammalian left-right development.	DNAH1 DNAH11	3.20e-05	4	81	2	10652513
Pubmed	Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation.	TLN1 TLN2	3.20e-05	4	81	2	30242097
Pubmed	Biosynthesis of heparin/heparan sulfate. The D-glucosaminyl 3-O-sulfotransferase reaction: target and inhibitor saccharides.	HS3ST3B1 HS3ST3A1	3.20e-05	4	81	2	7744762
Pubmed	Structural diversity in integrin/talin interactions.	TLN1 TLN2	3.20e-05	4	81	2	21134644
Pubmed	Expression of heparan sulfate D-glucosaminyl 3-O-sulfotransferase isoforms reveals novel substrate specificities.	HS3ST3B1 HS3ST3A1	3.20e-05	4	81	2	9988768
Pubmed	Exome sequencing in seven families and gene-based association studies indicate genetic heterogeneity and suggest possible candidates for fibromuscular dysplasia.	DYNC2H1 RNF213	3.20e-05	4	81	2	26147384
Pubmed	Regulation of the Ca(2+) channel TRPV6 by the kinases SGK1, PKB/Akt, and PIKfyve.	PIKFYVE SGK1	3.20e-05	4	81	2	20041238
Pubmed	Mutations in dynein genes in patients affected by isolated non-syndromic asthenozoospermia.	DNAH1 DNAH11	3.20e-05	4	81	2	18492703
Pubmed	Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1-haploinsufficient osteoclast functions.	TNFSF11 PIK3R1	3.20e-05	4	81	2	17053831
Pubmed	Vinculin regulates assembly of talin: β3 integrin complexes.	TLN1 TLN2	3.20e-05	4	81	2	24446374
Pubmed	Endothelial cell talin1 is essential for embryonic angiogenesis.	TLN1 TLN2	3.20e-05	4	81	2	21081121
Pubmed	Intrasteric inhibition mediates the interaction of the I/LWEQ module proteins Talin1, Talin2, Hip1, and Hip12 with actin.	TLN1 TLN2	3.20e-05	4	81	2	15581353
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	SETX DERL1 PDHA1 RNF213 TOPORS SBNO2	3.49e-05	262	81	6	36880596
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	MGAM SERPINA3 TGM2 CPNE8 CPNE6 CPNE9 GLG1 TLN1 DYSF CPNE5 ENO1	3.76e-05	1070	81	11	23533145
Pubmed	POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.	ALKBH1 SETX DNAJC14 GLG1 HERC1 ENO1	4.76e-05	277	81	6	30745168
Pubmed	Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction.	TLN1 TLN2	5.33e-05	5	81	2	19805288
Pubmed	RANKL-induced down-regulation of CX3CR1 via PI3K/Akt signaling pathway suppresses Fractalkine/CX3CL1-induced cellular responses in RAW264.7 cells.	TNFSF11 PIK3R1	5.33e-05	5	81	2	17963723
Pubmed	Talin1 regulates integrin turnover to promote embryonic epithelial morphogenesis.	TLN1 TLN2	5.33e-05	5	81	2	21670148
Pubmed	Quantification of integrin receptor agonism by fluorescence lifetime imaging.	TLN1 TLN2	5.33e-05	5	81	2	18216331
Pubmed	Mutational analysis of genes with ureteric progenitor cell-specific expression in branching morphogenesis of the mouse kidney.	HS3ST3B1 HS3ST3A1	5.33e-05	5	81	2	32017326
Pubmed	The phosphatidylinositol 3' kinase pathway is required for the survival signal of leukocyte tyrosine kinase.	PIK3C2B PIK3R1	5.33e-05	5	81	2	9223670
Pubmed	The proto-oncogene product p120(cbl) links c-Src and phosphatidylinositol 3'-kinase to the integrin signaling pathway.	PIK3R1 ENO1	5.33e-05	5	81	2	9013636
Pubmed	Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin.	TLN1 TLN2	5.33e-05	5	81	2	26821125
Pubmed	Proteome analysis of the circadian clock protein PERIOD2.	CPNE8 CPNE9 TLN1 ENO1	7.10e-05	94	81	4	35122331
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	RNF220 RNF213 UBR3 HERC1	7.40e-05	95	81	4	29643511
Pubmed	Human ltk receptor tyrosine kinase binds to PLC-gamma 1, PI3-K, GAP and Raf-1 in vivo.	PIK3C2B PIK3R1	7.99e-05	6	81	2	8084603
Pubmed	Mice carrying a complete deletion of the talin2 coding sequence are viable and fertile.	TLN1 TLN2	7.99e-05	6	81	2	22925892
Pubmed	Defining the membrane proteome of NK cells.	DNAJC14 DERL1 MYO9B PARP16 GLG1 PIK3R1 RNF213 KRR1 LARP4 ENO1 LAX1	8.25e-05	1168	81	11	19946888
Pubmed	Talin regulates integrin β1-dependent and -independent cell functions in ureteric bud development.	TLN1 TLN2	1.12e-04	7	81	2	28993400
Pubmed	Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.	DNAH1 DNAH11	1.12e-04	7	81	2	9256245
Pubmed	Monitoring α-synuclein ubiquitination dynamics reveals key endosomal effectors mediating its trafficking and degradation.	VPS13C PSMB1	1.12e-04	7	81	2	37315142
Pubmed	Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload.	TLN1 TLN2	1.12e-04	7	81	2	23266827
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	RNF220 DERL1 PIK3C2B GLG1 RNF213 HERC1 TOPORS	1.33e-04	481	81	7	28190767
Pubmed	The small muscle-specific protein Csl modifies cell shape and promotes myocyte fusion in an insulin-like growth factor 1-dependent manner.	TLN1 TLN2	1.49e-04	8	81	2	11381084
Pubmed	Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling.	PIK3R1 LAX1	1.49e-04	8	81	2	12359715
Pubmed	β2 integrin adhesion complexes maintain the integrity of HIV-1 assembly compartments in primary macrophages.	TLN1 TLN2	1.49e-04	8	81	2	22017400
Pubmed	Arginylation-dependent neural crest cell migration is essential for mouse development.	TLN1 TLN2	1.49e-04	8	81	2	20300656
Pubmed	Microtubule-associated protein 6 mediates neuronal connectivity through Semaphorin 3E-dependent signalling for axonal growth.	PIK3R1 SEMA3E	1.49e-04	8	81	2	26037503
Pubmed	Comparative phenotypic analysis of the two major splice isoforms of phosphatidylinositol phosphate kinase type Iγ in vivo.	TLN1 TLN2	1.91e-04	9	81	2	22976293
Pubmed	Efficient conditional and promoter-specific in vivo expression of cDNAs of choice by taking advantage of recombinase-mediated cassette exchange using FlEx gene traps.	NUP42 MSI2	1.91e-04	9	81	2	20139417
Pubmed	Dual phosphorylation of phosphoinositide 3-kinase adaptor Grb2-associated binder 2 is responsible for superoxide formation synergistically stimulated by Fc gamma and formyl-methionyl-leucyl-phenylalanine receptors in differentiated THP-1 cells.	PIK3R1 ENO1	1.91e-04	9	81	2	14530346
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	HMCN2 CWC27 SLTM CDH23 TLN2 ENO1	2.02e-04	361	81	6	26167880
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	ERP44 ZKSCAN1 TRIO KRR1 ENO1 SEZ6 MSI2 DNAH11	2.05e-04	689	81	8	36543142
Pubmed	Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.	ZNF462 SETX DERL1 ZKSCAN1	2.14e-04	125	81	4	32891193
Pubmed	The HIV-1 nef protein interferes with phosphatidylinositol 3-kinase activation 1.	PIK3C2B PIK3R1	2.38e-04	10	81	2	8636073
Pubmed	Extracellular human immunodeficiency virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells.	PIK3C2B PIK3R1	2.38e-04	10	81	2	8798481
Pubmed	Strawberry notch homologue 2 regulates osteoclast fusion by enhancing the expression of DC-STAMP.	TNFSF11 SBNO2	2.38e-04	10	81	2	23980096
Pubmed	Expression of HIV-1 nef decreases basal phosphatidyl-inositol 3-kinase activity.	PIK3C2B PIK3R1	2.38e-04	10	81	2	9247029
Pubmed	Assembly of the cochlear gap junction macromolecular complex requires connexin 26.	TLN1 TLN2	2.38e-04	10	81	2	24590285
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SETX COQ8A VPS13C ZZEF1 CEMIP2 DMAP1 SEMA3E	2.38e-04	529	81	7	14621295
Pubmed	Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport.	SGK1 PSMB1 ENO1	2.62e-04	53	81	3	14499622
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	ERP44 TRIO COQ8A PDHA1 PIK3R1 TLN1 PSMB1 KAZN NUP42	2.81e-04	916	81	9	32203420
Pubmed	HIV-1 gp120-induced TNF-{alpha} production by primary human macrophages is mediated by phosphatidylinositol-3 (PI-3) kinase and mitogen-activated protein (MAP) kinase pathways.	PIK3C2B PIK3R1	2.91e-04	11	81	2	16081599
Pubmed	HIV-1 Tat induces tyrosine phosphorylation of p125FAK and its association with phosphoinositide 3-kinase in PC12 cells.	PIK3C2B PIK3R1	2.91e-04	11	81	2	9708406
Pubmed	HIV-Nef enhances interleukin-2 production and phosphatidylinositol 3-kinase activity in a human T cell line.	PIK3C2B PIK3R1	2.91e-04	11	81	2	10985305
Pubmed	Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells.	PIK3C2B PIK3R1	2.91e-04	11	81	2	12584329
Pubmed	Ligands of CD4 inhibit the association of phospholipase Cgamma1 with phosphoinositide 3 kinase in T cells: regulation of this association by the phosphoinositide 3 kinase activity.	PIK3C2B PIK3R1	2.91e-04	11	81	2	9808187
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	TGM2 ALKBH1 SETX PDHA1 MYO9B TLN1 PSMB1 SLTM KRR1 LARP4 ENO1	2.96e-04	1353	81	11	29467282
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	HSPA12A SETX PARP16 RNF213 NUP42	3.03e-04	250	81	5	33536335
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	PIKFYVE TGM2 ERP44 TRIO VPS13C RNF213 LARP4 CEMIP2	3.11e-04	733	81	8	34672954
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	SETX TNFSF11 VPS13C TLN1 RNF213 KAZN ZZEF1 FBN3	3.20e-04	736	81	8	29676528
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	TGM2 CPNE8 SETX COQ8A PDHA1 TLN1 KRR1 LARP4 ENO1 TAF1D MSI2	3.31e-04	1371	81	11	36244648
Cytoband	Ensembl 112 genes in cytogenetic band chr15q22	PARP16 VPS13C SLTM TLN2 HERC1	3.92e-06	132	81	5	chr15q22
GeneFamily	Copines	CPNE8 CPNE6 CPNE9 CPNE5	1.36e-08	9	60	4	829
GeneFamily	Ferlin family	DYSF FER1L5	1.61e-04	6	60	2	828
GeneFamily	UPF1 like RNA helicases	SETX MOV10L1	5.84e-04	11	60	2	1169
GeneFamily	Dyneins, axonemal	DNAH1 DNAH11	1.43e-03	17	60	2	536
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM EFCAB6 MROH2A TLN2 ST18 DNAH1 DNAH11	4.21e-08	184	80	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM EFCAB6 MROH2A TLN2 ST18 DNAH1 DNAH11	4.21e-08	184	80	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM EFCAB6 MROH2A TLN2 ST18 DNAH1 DNAH11	4.21e-08	184	80	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPA12A SGK1 CPNE5 MYRF SEMA3E DNAH11	1.18e-06	189	80	6	98f517af255ef234eefc3ed7e6c1d63331ab8af0
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPA12A SGK1 CPNE5 MYRF SEMA3E DNAH11	1.18e-06	189	80	6	f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCell	droplet-Kidney-nan-3m-Lymphocytic-CD45____T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPNE6 TNFSF11 PLCXD2 MROH2A CYP4F22	1.35e-05	169	80	5	3c4c3279cd72f39b5e7ff77741950ed3873c0317
ToppCell	droplet-Kidney-nan-3m-Lymphocytic-T_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPNE6 TNFSF11 PLCXD2 MROH2A CYP4F22	1.35e-05	169	80	5	d6437afa298c280d202ba686338c6d8a37bd7ab7
ToppCell	TCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma-Usual_Type-4\|TCGA-Adrenal / Sample_Type by Project: Shred V9	SERPINA3 HOXC13 ST3GAL5 MYO9B KAZN	1.55e-05	174	80	5	15e2b9f46404ff9575e149024b24cb17b50b02b5
ToppCell	RSV-Healthy-1\|Healthy / Virus stimulation, Condition and Cluster	MYO9B RNF213 TLN2 CPNE5 CEMIP2	1.60e-05	175	80	5	ff3a27f512a3a710ebc863b7b75cce8167d5440b
ToppCell	RSV-Healthy-1\|RSV / Virus stimulation, Condition and Cluster	MYO9B RNF213 TLN2 CPNE5 CEMIP2	1.60e-05	175	80	5	ca52b99b03535a5b3a2751d6981708dc5b255b91
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EFCAB6 LINGO3 CPNE5 LAX1 DNAH11	1.69e-05	177	80	5	86c41d262142eeaa95ea7fa6668169eb1bb2953f
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Ly6g5b+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF462 TNFSF11 PIK3R1 HS3ST3B1 LAX1	1.83e-05	180	80	5	5c649e2b3f5a53c0040b69df6e289fb3427ef2db
ToppCell	droplet-Lung-nan-3m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPNE8 HSPA12A SGK1 CPNE5 SEMA3E	1.98e-05	183	80	5	ec3c05b9ce1e0fbb720e0dea41f1e28fd3fd878f
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-immature_innate_lymphoid_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZNF462 TNFSF11 PIK3R1 HS3ST3B1 LAX1	2.03e-05	184	80	5	3d8008f8d2e39c0d7a3cabc45620027491da03cf
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZNF462 TNFSF11 PIK3R1 HS3ST3B1 LAX1	2.03e-05	184	80	5	eeed75984ff111c0d1750df2f978163a42f20207
ToppCell	droplet-Lung-nan-3m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPNE8 HSPA12A SGK1 CPNE5 SEMA3E	2.03e-05	184	80	5	3261d767d5e3d9e9fbac22ad73ca14e44beed89c
ToppCell	Control-B_intermediate-6\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PIKFYVE ST3GAL5 TLN1 RNF213 CPNE5	2.31e-05	189	80	5	11cb9a16f1de8f60af2073ed7ea6d4f41c02f299
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TGM2 PIK3C2B DYSF HS3ST3A1 CEMIP2	2.37e-05	190	80	5	656483751e4bf137e4e4bfb2a03a478a8f7fcb63
ToppCell	control-Lymphoid-CTL\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SETX PIK3R1 RNF213 MSI2 CDC7	2.55e-05	193	80	5	89d407a88b5956559a589425b89b3eb8dc78e1dd
ToppCell	VE-mDC1-\|VE / Condition, Cell_class and T cell subcluster	ZNF462 P2RY6 SGK1 DYSF ST18	2.55e-05	193	80	5	5df6033bc0e4f96a20d526486a8e89c990e21831
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TGM2 CPNE8 PIK3C2B DYSF CEMIP2	2.55e-05	193	80	5	ad2df9b77999780860141be6ec366afc0172a331
ToppCell	VE-mDC1\|VE / Condition, Cell_class and T cell subcluster	ZNF462 P2RY6 SGK1 DYSF ST18	2.55e-05	193	80	5	12b2708db9db8b88365b8ebeb4908f28c50081bb
ToppCell	RA\|World / Chamber and Cluster_Paper	TGM2 CPNE8 KAZN CEMIP2 MSI2	2.62e-05	194	80	5	08f0afbb68a63150fbe107a5337299081c3f69e4
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	PIK3R1 VPS13C RNF213 CEMIP2 TAF1D	2.82e-05	197	80	5	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	PIK3R1 VPS13C RNF213 CEMIP2 TAF1D	2.89e-05	198	80	5	44417089b62056269cac38d3134ff209c05b7007
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PIK3R1 VPS13C RNF213 CEMIP2 TAF1D	2.89e-05	198	80	5	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	Sigmoid-(5)_Dendritic_cell-(51)_cDC1\|Sigmoid / shred on region, Cell_type, and subtype	TGM2 P2RY6 LINGO3 DYSF ST18	3.03e-05	200	80	5	4ce0a2238c90622e41fd86ac4b7d82adf4af2c3b
ToppCell	Sigmoid-Dendritic_cell-cDC1\|Sigmoid / Region, Cell class and subclass	TGM2 P2RY6 LINGO3 DYSF ST18	3.03e-05	200	80	5	3523ec986e8c9e176e08836c974b1de8b56d8b16
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ZNF462 P2RY6 DYSF ST18	1.35e-04	145	80	4	f6ba6cf0c8d0ee87a7904485b27eb9261fcb6edd
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	POGK PIK3R1 L2HGDH ENO1	1.35e-04	145	80	4	23a1ee986774725a9f5a9154fbbd023031fb0452
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	POGK PLCXD2 LAX1 CDC7	1.50e-04	149	80	4	65778f19599b4955c0a16f0121237656449431fb
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-8\|TCGA-Bladder / Sample_Type by Project: Shred V9	PIK3C2B POGK CYP4F22 MSI2	1.54e-04	150	80	4	1aa9320d97ff10994ea024751790524fe133aba9
ToppCell	Adult-Immune-mast_cell-D231\|Adult / Lineage, Cell type, age group and donor	SGK1 MOV10L1 CYP4F22 LAX1	1.84e-04	157	80	4	4c63bb91f8708644e6ce2500072a4eeb8e1079dd
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	POGK PLCXD2 PIK3R1 LAX1	1.97e-04	160	80	4	6b0faaa371650563f585722f5b2fb319e124ec38
ToppCell	CD8+_Memory_T_cell-RSV-1\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	TLN2 CPNE5 ENO1 CEMIP2	2.02e-04	161	80	4	f6d04f67da3557e80f13ef27bfabb94dcd80db2f
ToppCell	CD8+_Memory_T_cell-FLU-1\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	CPNE5 ENO1 MYRF CEMIP2	2.07e-04	162	80	4	76f39935763848ea6e7917b2f9f1432c543063d9
ToppCell	Healthy_Control-Lymphoid-Plasma\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	PARP16 CPNE5 LAX1 MSI2	2.12e-04	163	80	4	2913ccdd4613472cd82077d4993e1d9f8b223398
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POGK PLCXD2 PIK3R1 LAX1	2.12e-04	163	80	4	a0315855c354e830e109d41bd6e3396488aa8de9
ToppCell	Healthy_Control-Lymphoid-Plasma-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	PARP16 CPNE5 LAX1 MSI2	2.12e-04	163	80	4	b589ff57d58dcb215ee3b5a10d81f43e5752a196
ToppCell	droplet-Lung-LUNG-1m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	POGK PLCXD2 PIK3R1 LAX1	2.17e-04	164	80	4	a59078c8f88e416e940c9b15151ce7de1bbe987e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TGM2 CYP4F22 HS3ST3B1 CDC7	2.32e-04	167	80	4	b4ef07117d14da3d5fbced949e4dfcb01c392295
ToppCell	droplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	POGK PLCXD2 PIK3R1 LAX1	2.32e-04	167	80	4	895844a45721988788d01120eb880603ba3ca139
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TGM2 CYP4F22 HS3ST3B1 CDC7	2.32e-04	167	80	4	94fc7df7ca55cd722a8dbd153201a29891217473
ToppCell	droplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	POGK PLCXD2 PIK3R1 LAX1	2.32e-04	167	80	4	cde82e3dacf347226a78873b166608b7851b34d4
ToppCell	droplet-Lung-1m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	POGK PLCXD2 PIK3R1 LAX1	2.32e-04	167	80	4	6f54a699d9266c5f09ed890a11b403a6c8476fc1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TGM2 CYP4F22 HS3ST3B1 CDC7	2.32e-04	167	80	4	eff3723fe60755272eca237459165e436e919ece
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM RNF220 PLCXD2 ST18	2.38e-04	168	80	4	f3164a85e5630ee8a745c6dba298e1f94ba4d5b8
ToppCell	5'-Adult-LymphNode-Hematopoietic-Plasma_cells-IgG_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNF213 CPNE5 LAX1 SBNO2	2.38e-04	168	80	4	f5a18123f84c62211d9279e9c41e90122e4c4895
ToppCell	BAL-Control-cDC_6\|Control / Compartment, Disease Groups and Clusters	ZKSCAN1 TLN2 LINGO3 SEZ6	2.38e-04	168	80	4	65ec473cff748b334c0a66e33bc34a8465fe7631
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RNF220 PLCXD2 HS3ST3B1 SEMA3E	2.43e-04	169	80	4	1c9e54e7b14eb99996590fb93b257cf881a9f184
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	P2RY6 TOPORS SEZ6 DNAH11	2.43e-04	169	80	4	29db25e7c5f31d98a08a35d7ec5ade203242bc50
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EFCAB6 DYNC2H1 DNAH1 DNAH11	2.43e-04	169	80	4	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related-Oligodendrocyte/OPC\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	P2RY6 TOPORS SEZ6 DNAH11	2.43e-04	169	80	4	b1611e61f635f8f9b87250e026ad30999cbee041
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-Myeloid-cDC1\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST3GAL5 P2RY6 DYSF ST18	2.43e-04	169	80	4	da3485d77bb7876fad4f166f6099e681b27457ae
ToppCell	Bronchial_Brush-Immune-B_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	PIKFYVE CPNE5 LAX1 MSI2	2.49e-04	170	80	4	53e9372cb06a2dc5c8ecb3f9af42f3c23da96431
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPNE8 HSPA12A P2RY6 SGK1	2.54e-04	171	80	4	a474aaed3ca4cacb0ab565c35f25d92a10f531b7
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TGM2 COQ8A CPNE5 SEZ6	2.72e-04	174	80	4	3c47d069bd836599a8d40eae485c23d4d3487517
ToppCell	5'-Adult-LymphNode-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RNF213 CPNE5 LAX1 SBNO2	2.78e-04	175	80	4	6a093c74a6f3daeff07759d6eec542fc5c709149
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_GGH\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HS3ST3B1 HS3ST3A1 FBN3 SEZ6	2.84e-04	176	80	4	23f930dac5247ea6d4124da33933d61ad6e089af
ToppCell	facs-Aorta\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGM2 MROH2A DYSF DNAH11	2.84e-04	176	80	4	0b3491451be02c18a16cdb875645be47eb867a7f
ToppCell	facs-GAT-Fat-24m-Lymphocytic-B_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COQ8A PIK3C2B CDH23 LAX1	2.90e-04	177	80	4	f4afe10522eed77318954210224496f09d372532
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_GGH\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HS3ST3B1 HS3ST3A1 FBN3 SEZ6	2.90e-04	177	80	4	d7976eac7e27044f6a859cc0c3398d08576e8c01
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MGAM SERPINA3 TGM2 P2RY6	2.90e-04	177	80	4	709235694cc711b9b79690e23c94577b2ae06811
ToppCell	356C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MGAM SERPINA3 TGM2 P2RY6	2.90e-04	177	80	4	7f9c2a45a994b32f15e5693f7cb873716a4eb568
ToppCell	droplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PARP16 TONSL CPNE5 DNAH11	2.96e-04	178	80	4	de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_2\|356C / Donor, Lineage, Cell class and subclass (all cells)	EEF1AKMT3 TONSL LAX1 CDC7	2.96e-04	178	80	4	8b939659f713eea50a1a6e28b571f680ca0b4c12
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPA12A TNFSF11 CPNE5 SEMA3E	2.96e-04	178	80	4	ef490b45901b2e6dedb519540fa3ae4e4db3a9ba
ToppCell	FF-Differ-KC\|World / shred by cell class for mouse tongue	HOXC13 HS3ST3B1 SEMA3E DNAH11	3.03e-04	179	80	4	1526a130565a97c291a25a7a988089bffc1515c1
ToppCell	normal_Lymph_Node-Myeloid_cells-CD141+_DCs\|normal_Lymph_Node / Location, Cell class and cell subclass	ZNF462 P2RY6 DYSF ST18	3.03e-04	179	80	4	ec995ccd6e1dbd06287ad836c232d9aed1cf94a8
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPA12A LINGO3 CPNE5 SEZ6	3.03e-04	179	80	4	a3922476f33d2e4137a12dbda21a1703dff79684
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLCXD2 MYRF FBN3 MYORG	3.03e-04	179	80	4	d5e3e7f1cd8f683f39a7416f12af7e766dcbead8
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TGM2 HMCN2 MOV10L1 MYORG	3.03e-04	179	80	4	8c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HS3ST3B1 HS3ST3A1 FBN3 SEZ6	3.09e-04	180	80	4	c6030e725e3d86d5d74a1676330c77ffeceb324f
ToppCell	Control-Myeloid-Dendritic_cells\|Control / group, cell type (main and fine annotations)	MGAM MYO9B SGK1 ST18	3.09e-04	180	80	4	25ad95c3c30e3b82abe93bd77ba003f5c2241f7c
ToppCell	COPD-Lymphoid-T_Regulatory\|World / Disease state, Lineage and Cell class	HS3ST3B1 LAX1 CEMIP2 MSI2	3.09e-04	180	80	4	51a12fbad5fa7bb12e6d616a02ff9b5141e2b063
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGM2 CPNE8 MROH2A CEMIP2	3.16e-04	181	80	4	cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-DC-cDC2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TGM2 HMCN2 SGK1 ST18	3.22e-04	182	80	4	1d37c486173cc4629842893ddd5033987c04086f
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-DC-cDC2-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TGM2 HMCN2 SGK1 ST18	3.22e-04	182	80	4	aef67bdc6937b315522d39959e26c9b0acf7ab52
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-DC\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TGM2 HMCN2 SGK1 ST18	3.22e-04	182	80	4	087c9f88daf08f5d688b728c2386f91f210d2255
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TGM2 CPNE8 PIK3C2B DYSF	3.29e-04	183	80	4	bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell	Mild/Remission-B_intermediate-10\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PIKFYVE MYO9B TLN1 CEMIP2	3.29e-04	183	80	4	278064c9f0582463b83bf156d34e77f60187613b
ToppCell	343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	DERL1 LAX1 SBNO2 SEZ6	3.36e-04	184	80	4	2c2125b8030af83f7a6d59a7102d4de8e0ac1988
ToppCell	Control-CD8+_T_activated\|Control / Disease group and Cell class	CPNE8 ERP44 DERL1 NUP42	3.36e-04	184	80	4	b86cc48b744b3206880ec1373fe6068e14bf9680
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TGM2 HMCN2 SEMA3E DNAH11	3.36e-04	184	80	4	590fb32bb1f348ea5fa2aece30ebe1e212512991
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TGM2 HS3ST3B1 HS3ST3A1 SEMA3E	3.43e-04	185	80	4	7dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCell	normal-na-Lymphocytic_NK-NK_dim-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	PIK3R1 TLN1 RNF213 CEMIP2	3.43e-04	185	80	4	b1a8a8c4d0fc7605eabc17dcb6bd9e8ab4fd578c
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TGM2 HS3ST3B1 HS3ST3A1 SEMA3E	3.57e-04	187	80	4	5258674d0346e5c51a4b965efcdc1790c970845d
ToppCell	AT1_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	PLCXD2 MROH2A MYRF FBN3	3.57e-04	187	80	4	f1dda349335e08dbfc8395d373924037f5ad2fd6
ToppCell	P03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TGM2 CPNE8 P2RY6 CEMIP2	3.64e-04	188	80	4	5eb107122064f0a99dfd445cc87d3766f7257216
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	VPS13C RNF213 HERC1 CEMIP2	3.64e-04	188	80	4	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CPNE8 PIK3C2B DYSF CPNE5	3.64e-04	188	80	4	b66f1f08827dd6c48583d871f9f33ea41e48bfb2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF462 TRIO KAZN DNAH11	3.64e-04	188	80	4	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF462 TGM2 SGK1 SEMA3E	3.72e-04	189	80	4	d00410010283dc6191ce9857d6c7952678fed588
ToppCell	renal_cortex_nuclei-Adult_normal_reference\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM CPNE6 GLG1 ST18	3.72e-04	189	80	4	a48df46274d51e84ffb40264646de7346104efb9
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RNF220 ST3GAL5 FBN3 SEMA3E	3.79e-04	190	80	4	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPNE8 ZKSCAN1 VPS13C LARP4	3.79e-04	190	80	4	36e83995021ba16690f84e2077a9e8baec547d05
ToppCell	P07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TGM2 CPNE8 P2RY6 CEMIP2	3.79e-04	190	80	4	e1b721bb74561fe51c53328a0394c9954e489049
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PIK3R1 RNF213 LAX1 CEMIP2	3.79e-04	190	80	4	d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCell	facs-Marrow-KLS-18m-Hematologic-MPP_Fraction_A_+_HSC\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGM2 CPNE8 COQ8A MSI2	3.79e-04	190	80	4	96a9756cad5468a12591021e6d661ed269b5b3d9
ToppCell	facs-Trachea-24m-Hematologic-lymphocytic\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNFSF11 PLCXD2 ENO1 LAX1	3.79e-04	190	80	4	10f7d33fd1ff096f8fe5b7b11a58819d6cc14fbc
Drug	retinoic acid; Up 200; 1uM; MCF7; HT_HG-U133A_EA	SERPINA3 TGM2 HOXC13 ZKSCAN1 ST3GAL5 DYNC2H1 KAZN	2.50e-06	170	81	7	849_UP
Drug	Flavoxate hydrochloride [3717-88-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A	TRIO PDHA1 SGK1 PIK3R1 NUP42 SBNO2 TAF1D	5.21e-06	190	81	7	7405_DN
Drug	Cimetidine [51481-61-9]; Up 200; 15.8uM; HL60; HG-U133A	MGAM DERL1 ZKSCAN1 PIK3C2B MYO9B PARP16 SGK1	7.06e-06	199	81	7	1964_UP
Drug	rapamycin; Down 200; 0.1uM; ssMCF7; HG-U133A	TRIO PIK3C2B MYO9B SGK1 GLG1 TLN2 SBNO2	7.06e-06	199	81	7	402_DN
Drug	halenaquinone	PIKFYVE PIK3C2B PIK3R1	1.53e-05	14	81	3	CID000370346
Drug	4-hydroxyisoleucine	PIKFYVE PIK3C2B PIK3R1	1.91e-05	15	81	3	CID000354197
Drug	monomethyl phthalate	PIKFYVE MGAM PIK3C2B PLCXD2 PIK3R1 ENO1	1.92e-05	155	81	6	CID000020392
Drug	MolPort-016-580-972	PIKFYVE TNFSF11 PIK3R1 TONSL	3.27e-05	51	81	4	CID009938589
Drug	diethylmagnesium	MGAM ENO1	3.74e-05	3	81	2	CID000011183
Drug	phenylphosphanide	MGAM ENO1	3.74e-05	3	81	2	CID011106096
Drug	Progesterone [57-83-0]; Down 200; 12.8uM; HL60; HT_HG-U133A	ERP44 MYO9B DYNC2H1 PARP16 GLG1 KAZN	5.35e-05	186	81	6	2426_DN
Drug	Azacyclonol [115-46-8]; Down 200; 15uM; PC3; HG-U133A	DERL1 PDHA1 NUP42 KRR1 LARP4 ENO1	6.39e-05	192	81	6	1937_DN
Drug	Mexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; PC3; HT_HG-U133A	TRIO TLN1 TLN2 KAZN MYRF SBNO2	6.57e-05	193	81	6	4338_DN
Drug	Etofylline [519-37-9]; Down 200; 17.8uM; HL60; HG-U133A	DERL1 PIK3C2B KRR1 TOPORS LARP4 CDC7	6.76e-05	194	81	6	1409_DN
Drug	Indapamide [26807-65-8]; Down 200; 10.6uM; PC3; HT_HG-U133A	TRIO P2RY6 TLN1 KAZN MYRF SBNO2	6.76e-05	194	81	6	4335_DN
Drug	Nilutamide [63612-50-0]; Down 200; 12.6uM; PC3; HT_HG-U133A	TRIO TLN1 PSMB1 TLN2 ZZEF1 SBNO2	6.76e-05	194	81	6	6763_DN
Drug	WY-14643; Up 200; 100uM; MCF7; HG-U133A	TRIO PIK3C2B MYO9B TLN2 NUP42 SBNO2	6.96e-05	195	81	6	368_UP
Drug	Chlorthalidone [77-36-1]; Down 200; 11.8uM; PC3; HT_HG-U133A	TGM2 ZKSCAN1 ST3GAL5 MYO9B TLN2 KAZN	6.96e-05	195	81	6	7152_DN
Drug	1,1-dimethylbiguanide hydrochloride; Down 200; 0.1uM; MCF7; HG-U133A	HSPA12A GLG1 VPS13C LARP4 DYSF CEMIP2	7.36e-05	197	81	6	3_DN
Drug	[2-(oxidoamino)-2-oxoethyl]phosphonic acid	MGAM ENO1	7.47e-05	4	81	2	CID011969443
Drug	platensimycin	PIKFYVE COQ8A PIK3C2B PIK3R1	7.55e-05	63	81	4	CID006857724
Drug	Rilmenidine hemifumarate [54187-04-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A	ZKSCAN1 TRIO GLG1 TLN2 TOPORS LAX1	7.57e-05	198	81	6	5532_DN
Drug	Isoxsuprine hydrochloride [579-56-6]; Up 200; 11.8uM; HL60; HG-U133A	MGAM EEF1AKMT3 MYO9B PARP16 GLG1 SBNO2	7.57e-05	198	81	6	1985_UP
Drug	Mefenamic acid [61-68-7]; Up 200; 16.6uM; HL60; HT_HG-U133A	P2RY6 PIK3R1 L2HGDH KAZN CEMIP2 SBNO2	7.78e-05	199	81	6	1863_UP
Drug	Metixene hydrochloride [1553-34-0]; Down 200; 11.6uM; PC3; HT_HG-U133A	ST3GAL5 P2RY6 PIK3R1 TLN2 LAX1 SBNO2	7.78e-05	199	81	6	6672_DN
Drug	Amrinone [60719-84-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A	ERP44 TRIO MYO9B TLN1 DYSF SBNO2	7.78e-05	199	81	6	6826_DN
Drug	rapamycin; Up 200; 0.1uM; MCF7; HG-U133A	HOXC13 TRIO COQ8A PIK3C2B GLG1 KRR1	7.78e-05	199	81	6	326_UP
Drug	Aztreonam [78110-38-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A	ERP44 TRIO ST3GAL5 DYNC2H1 HS3ST3A1 LAX1	7.78e-05	199	81	6	5535_DN
Drug	oxamic acid sodium salt; Down 200; 10000uM; MCF7; HG-U133A	TGM2 MYO9B TLN2 NUP42 LARP4 DYSF	7.78e-05	199	81	6	439_DN
Disease	anterior thigh muscle fat infiltration measurement	HMCN2 PIK3R1 DYSF	5.55e-05	28	78	3	EFO_0020936
Disease	posterior thigh muscle fat infiltration measurement	HMCN2 PIK3R1 DYSF	1.09e-04	35	78	3	EFO_0020934
Disease	Degenerative polyarthritis	TGM2 PDHA1 PSMB1 ENO1	1.10e-04	93	78	4	C0029408
Disease	Osteoarthrosis Deformans	TGM2 PDHA1 PSMB1 ENO1	1.10e-04	93	78	4	C0086743
Disease	heart rate variability measurement	RNF220 CPNE8 CPNE5	1.29e-04	37	78	3	EFO_0008003
Disease	limb-girdle muscular dystrophy (implicated_via_orthology)	DYSF FER1L5	1.44e-04	7	78	2	DOID:11724 (implicated_via_orthology)
Disease	alpha-1-antichymotrypsin complex measurement	PIKFYVE SERPINA3	1.44e-04	7	78	2	EFO_0008018
Disease	Ciliopathies	DYNC2H1 CDH23 TOPORS DNAH11	2.11e-04	110	78	4	C4277690
Disease	refractive error	ZNF462 ZZEF1 ST18 MYRF FBN3 MSI2	2.29e-04	326	78	6	MONDO_0004892
Disease	heart rate response to recovery post exercise	RNF220 CPNE8 CPNE5	4.69e-04	57	78	3	EFO_0009185
Disease	Osteoporosis, Age-Related	TNFSF11 TLN1 ENO1	5.73e-04	61	78	3	C0001787
Disease	Post-Traumatic Osteoporosis	TNFSF11 TLN1 ENO1	5.73e-04	61	78	3	C0751406
Disease	Osteoporosis, Senile	TNFSF11 TLN1 ENO1	5.73e-04	61	78	3	C0029459
Disease	Osteoporosis	TNFSF11 TLN1 ENO1	6.30e-04	63	78	3	C0029456
Disease	resting heart rate	RNF220 CPNE8 CPNE5 MYRF	6.66e-04	149	78	4	EFO_0004351
Disease	freckles	HSPA12A MSI2	1.27e-03	20	78	2	EFO_0003963
Disease	brain infarction, neuritic plaque measurement, Lewy body dementia, cerebral amyloid angiopathy, neurofibrillary tangles measurement	SGK1 KAZN	1.54e-03	22	78	2	EFO_0004277, EFO_0006790, EFO_0006792, EFO_0006797, EFO_0006798
Disease	Bronchiectasis	PIK3R1 DNAH11	1.54e-03	22	78	2	C0006267
Disease	Dystonia	WDR45 L2HGDH MYORG	1.55e-03	86	78	3	C0013421
Disease	chronic widespread pain	KAZN LARP4	1.68e-03	23	78	2	EFO_0010099
Disease	disease free survival, response to mepolizumab	TGM2 HS3ST3A1	1.83e-03	24	78	2	EFO_0000409, EFO_0008459

Protein segments in the cluster

Peptide	Gene	Start	Entry
GSFLSKDFDARKAYP	DENND10P1	141	Q6NSW5
ESIYGAPFKDEFHSR	CWC27	76	Q6UX04
DAKRLYGSEAFATDF	SERPINA3	156	P01011
TEPGEDAFRKLFRFY	ALKBH1	16	Q13686
VFKPSLDREAGDGFY	DNAH11	956	Q96DT5
FPREVGLFADSYSEK	EEF1AKMT3	16	Q96AZ1
GFASRDFLSGRPFYK	FBN3	971	Q75N90
SYFFSDDPDRFSLDK	CDH23	496	Q9H251
YDSDKRFPAFGFGAR	CPNE6	351	O95741
QTSPDSLRDYFSKFG	MSI2	31	Q96DH6
YDDEESLKFPSDFSR	DNAJC14	171	Q6Y2X3
FSSKDPDFHDDYGSL	KAZN	731	Q674X7
VGAEPHFFDRSYDKG	HS3ST3B1	166	Q9Y662
FEDDRYFLGFLSNSK	MOV10L1	1116	Q9BXT6
LAFKREGYRPFDFSA	L2HGDH	331	Q9H9P8
PGSFIYVFSDARAKD	HMCN2	131	Q8NDA2
RDFTYDSVDFKGFPE	MGAM	421	O43451
FSEDRPFAVGYFDGK	HERC1	3591	Q15751
LETGAFDGRPADYLF	DERL1	86	Q9BUN8
PSLFLGDAYAARDKS	DUSP13	51	Q9UII6
KRTFLASGDYADFQP	LAX1	336	Q8IWV1
EYSFRKVDGPAAAAG	LINGO3	566	P0C6S8
EESSFATLFPKYREA	KRR1	56	Q13601
VGAEPHFFDRSYDKG	HS3ST3A1	181	Q9Y663
TPERKFHSFGYAARD	HSPA12A	106	O43301
FPGYDLSADDIAGKF	POGK	176	Q9P215
RDGKYGFSDPLTFSS	PIK3R1	386	P27986
GSRDQEKPYFSSFDS	NUP42	71	O15504
KFSPRYEFGSLREED	PIK3C2B	801	O00750
FDPANAKFYETKGER	PARP16	131	Q8N5Y8
KSGAAFYATEDDRFI	PIKFYVE	1861	Q9Y2I7
KRSAFPRFYFLSDDE	DNAH1	1321	Q9P2D7
EKRSAFPRFYFIGDD	DYNC2H1	1421	Q8NCM8
VAASEFFRSGKYDLD	ENO1	246	P06733
FFRSGKYDLDFKSPD	ENO1	251	P06733
YAAKVAPADGFSDLA	GLG1	1121	Q92896
PYSAFFKTDADRDGI	EFCAB6	746	Q5THR3
RAAEEGKDYPFARFN	DMAP1	116	Q9NPF5
SLLSGRYPFYKASDD	CDC7	406	O00311
DFAPSAAATSDFYKR	COLCA2	131	A8K830
GKSDPFLVFYRSNED	CPNE9	166	Q8IYJ1
DKLEYFEERPFAAAS	COQ8A	326	Q8NI60
GLPFGSYTFEKDFSR	CEMIP2	251	Q9UHN6
PGDDLSSRAKEFAFY	HOXC13	161	P31276
FLSAFGDVSKPERYS	ERP44	191	Q9BS26
EKPEARASKDYSGFR	LARP4	666	Q71RC2
PDDFSAGARGYLKTS	DYSF	326	O75923
SFDPVGSYQRDSFKA	PSMB1	151	P20618
GKSDPFLVFYRSNED	CPNE8	176	Q86YQ8
ASAAIAPKDDLFYGF	CYP4F22	121	Q6NT55
KSDPFLVFYRSNEDG	CPNE5	196	Q9HCH3
LEAFAAAYKGTRPFA	P2RY6	276	Q15077
SFDSPSLEKGFLYRA	MROH2A	676	A6NES4
YDFDLFSPDDKIGTT	FER1L5	1556	A0AVI2
FDSRRYKFLDDDGSI	TAF1D	191	Q9H5J8
VKEAAEAFLGFSYAP	SGK1	411	O00141
REDPSFERYPKNFSD	SLTM	811	Q9NWH9
GLSVTFDGKREDYFP	SETD3	66	Q86TU7
DFLKRYASNTPSGEF	SETX	16	Q7Z333
DSEAESKYDPPFGFR	ST3GAL5	151	Q9UNP4
EDAFAKSLALTGPYD	SBNO2	1051	Q9Y2G9
YSFPDNPRKLFEFDT	WDR45	126	Q9Y484
PHLRFSDADGKEYDF	RNF220	151	Q5VTB9
PFDYASFDAQVFGKR	ST18	501	O60284
EGDLSTKYDAPFVFA	TGM2	381	P21980
GYASLLFKLDPSVDF	RNF213	1471	Q63HN8
AAASTDYYKRGDFIP	PDHA1	236	P08559
RYFDLRVSSKPGDAD	PLCXD2	111	Q0VAA5
ASPKSFTLDFGDYQD	TLN1	361	Q9Y490
FSKAGDFPRAAEAYQ	TONSL	321	Q96HA7
DGFYNSRSLDVAKAP	SEZ6	901	Q53EL9
ASTFDYSLKDRAPFT	VPS13C	2411	Q709C8
PDQDATYFGAFKVRD	TNFSF11	301	O14788
DDFKEYVLRPSYNGS	TOPORS	156	Q9NS56
DYSKTPGSPDNDFLF	UBR3	1436	Q6ZT12
TFRSLCTYFSDKDPG	ZZEF1	896	O43149
ASDYGLFLSDEDPRK	TLN2	46	Q9Y4G6
KYADGAFADFKQERP	ZNF462	1936	Q96JM2
YGTTKDYPDDAIRFA	SEMA3E	391	O15041
EYSPASLDAFGAFLK	ZKSCAN1	546	P17029
RLDFSFPDDYFKGVS	TRIO	3006	O75962
LDEFTRGYTKNDFEP	MYO9B	1596	Q13459
KFDAGEVSYLPRDFS	MYORG	461	Q6NSJ0
RYKPEFAASAGIEAT	MYRF	616	Q9Y2G1