Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF13B MYH1 MYH2 APPBP2 MYH8 DNAI1 KIF15 KIF13A	1.22e-05	118	181	8	GO:0003774
GeneOntologyCellularComponent	microtubule associated complex	KIF13B APPBP2 KLC4 ACTR1B DNAI1 HAUS4 KIF15 RP1 KIF13A	1.16e-05	161	181	9	GO:0005875
GeneOntologyCellularComponent	presynaptic active zone	CACNA2D1 CACNA2D2 NTRK2 RIMS3 NAPB KCNMA1 CTNNA2 CD200	3.22e-05	141	181	8	GO:0048786
GeneOntologyCellularComponent	synaptic membrane	CACNA2D1 CACNA2D2 NTRK2 RIMS3 OPRL1 ARRB2 AP2B1 NAPB PTPRO KCNMA1 LRP1 ANP32E PRKCG LRRC7 CTNNA2 MUSK	5.01e-05	583	181	16	GO:0097060
GeneOntologyCellularComponent	muscle myosin complex	MYH1 MYH2 MYH8	3.29e-04	16	181	3	GO:0005859
Domain	-	APPBP2 CLTCL1 SGTA MAU2 UNC45A KLC4 TTC1 TRRAP TTC19 NAPB LONRF2 KDM6A CRTAP	1.04e-07	207	179	13	1.25.40.10
Domain	TPR-like_helical_dom	APPBP2 CLTCL1 SGTA MAU2 UNC45A KLC4 TTC1 TRRAP TTC19 NAPB LONRF2 KDM6A CRTAP	4.06e-07	233	179	13	IPR011990
Domain	TPR	APPBP2 SGTA MAU2 UNC45A KLC4 TTC1 TTC19 LONRF2 KDM6A	4.26e-06	129	179	9	SM00028
Domain	TPR_repeat	APPBP2 SGTA MAU2 UNC45A KLC4 TTC1 TTC19 LONRF2 KDM6A	5.48e-06	133	179	9	IPR019734
Domain	Groucho_enhance	TLE2 TLE3 TLE4	8.54e-06	5	179	3	IPR009146
Domain	TLE_N	TLE2 TLE3 TLE4	8.54e-06	5	179	3	PF03920
Domain	Groucho/TLE_N	TLE2 TLE3 TLE4	8.54e-06	5	179	3	IPR005617
Domain	TPR_10	APPBP2 KLC4 TTC19	1.70e-05	6	179	3	PF13374
Domain	TPR_REGION	APPBP2 SGTA MAU2 UNC45A KLC4 TTC1 TTC19 LONRF2 KDM6A	3.10e-05	165	179	9	PS50293
Domain	TPR	APPBP2 SGTA MAU2 UNC45A KLC4 TTC1 TTC19 LONRF2 KDM6A	3.10e-05	165	179	9	PS50005
Domain	-	COP1 WDR27 BIRC6 DNAI1 TLE2 TLE3 TLE4 MIOS LRBA PLXNA1 PLXNA2 FBXW7	9.19e-05	333	179	12	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	COP1 WDR27 BIRC6 DNAI1 TLE2 TLE3 TLE4 MIOS LRBA PLXNA1 PLXNA2 FBXW7	9.73e-05	335	179	12	IPR015943
Domain	TPR-contain_dom	APPBP2 SGTA UNC45A KLC4 TTC1 TTC19 LONRF2 KDM6A	1.01e-04	150	179	8	IPR013026
Domain	ARM-type_fold	CLTCL1 TNPO2 RANBP6 PPP6R1 UNC45A TRRAP HEATR6 AP2B1 EIF4G2 INTS4 ATM LRBA	1.09e-04	339	179	12	IPR016024
Domain	TPR_1	SGTA UNC45A KLC4 TTC1 LONRF2 KDM6A	2.28e-04	90	179	6	IPR001440
Domain	TPR_1	SGTA UNC45A KLC4 TTC1 LONRF2 KDM6A	2.28e-04	90	179	6	PF00515
Domain	Myosin_N	MYH1 MYH2 MYH8	3.62e-04	15	179	3	PF02736
Domain	Myosin_N	MYH1 MYH2 MYH8	3.62e-04	15	179	3	IPR004009
Domain	Kinesin-like_KIF1-typ	KIF13B KIF13A	5.41e-04	4	179	2	IPR022140
Domain	VDCC_a2/dsu	CACNA2D1 CACNA2D2	5.41e-04	4	179	2	IPR013680
Domain	KIF1B	KIF13B KIF13A	5.41e-04	4	179	2	PF12423
Domain	VGCC_alpha2	CACNA2D1 CACNA2D2	5.41e-04	4	179	2	PF08473
Domain	Myosin_tail_1	MYH1 MYH2 MYH8	6.35e-04	18	179	3	PF01576
Domain	Myosin_tail	MYH1 MYH2 MYH8	6.35e-04	18	179	3	IPR002928
Domain	LRR	LRRC58 LGR5 TLR4 NXF5 PPP1R37 ANP32E LRRC7 LRRD1	7.28e-04	201	179	8	PS51450
Domain	Myosin-like_IQ_dom	MYH1 MYH2 MYH8	7.49e-04	19	179	3	IPR027401
Domain	-	MYH1 MYH2 MYH8	7.49e-04	19	179	3	4.10.270.10
Domain	VWA_N	CACNA2D1 CACNA2D2	8.96e-04	5	179	2	IPR013608
Domain	VWA_N	CACNA2D1 CACNA2D2	8.96e-04	5	179	2	PF08399
Domain	WD40	COP1 WDR27 DNAI1 TLE2 TLE3 TLE4 MIOS LRBA FBXW7	1.15e-03	268	179	9	SM00320
Domain	Leu-rich_rpt	NTRK2 LRRC58 LGR5 TLR4 NXF5 PPP1R37 ANP32E LRRC7 LRRD1	1.24e-03	271	179	9	IPR001611
Domain	WD40_repeat	COP1 WDR27 DNAI1 TLE2 TLE3 TLE4 MIOS LRBA FBXW7	1.27e-03	272	179	9	IPR001680
Domain	Kinesin_assoc	KIF13B KIF13A	1.34e-03	6	179	2	PF16183
Domain	Kinesin-like	KIF13B KIF13A	1.34e-03	6	179	2	IPR022164
Domain	FAT	TRRAP ATM	1.34e-03	6	179	2	PS51189
Domain	FATC	TRRAP ATM	1.34e-03	6	179	2	PS51190
Domain	Kinesin_assoc	KIF13B KIF13A	1.34e-03	6	179	2	IPR032405
Domain	FAT	TRRAP ATM	1.34e-03	6	179	2	PF02259
Domain	PIK-rel_kinase_FAT	TRRAP ATM	1.34e-03	6	179	2	IPR003151
Domain	FATC_dom	TRRAP ATM	1.34e-03	6	179	2	IPR003152
Domain	DUF3694	KIF13B KIF13A	1.34e-03	6	179	2	PF12473
Domain	PIK_FAT	TRRAP ATM	1.34e-03	6	179	2	IPR014009
Domain	FATC	TRRAP ATM	1.34e-03	6	179	2	SM01343
Domain	-	TNPO2 RANBP6 UNC45A TRRAP HEATR6 AP2B1 INTS4 LRBA	1.38e-03	222	179	8	1.25.10.10
Domain	EGF_CA	THBS2 HMCN2 LRP1 UMOD LTBP1	1.42e-03	86	179	5	PF07645
Domain	WD_REPEATS_1	COP1 WDR27 DNAI1 TLE2 TLE3 TLE4 MIOS LRBA FBXW7	1.48e-03	278	179	9	PS00678
Domain	WD_REPEATS_2	COP1 WDR27 DNAI1 TLE2 TLE3 TLE4 MIOS LRBA FBXW7	1.52e-03	279	179	9	PS50082
Domain	WD_REPEATS_REGION	COP1 WDR27 DNAI1 TLE2 TLE3 TLE4 MIOS LRBA FBXW7	1.52e-03	279	179	9	PS50294
Domain	TPR_8	SGTA UNC45A TTC1 KDM6A	1.66e-03	53	179	4	PF13181
Domain	WD40_repeat_dom	COP1 WDR27 DNAI1 TLE2 TLE3 TLE4 MIOS LRBA FBXW7	2.32e-03	297	179	9	IPR017986
Domain	BIR	BIRC3 BIRC6	2.46e-03	8	179	2	PF00653
Domain	BIR_REPEAT_2	BIRC3 BIRC6	2.46e-03	8	179	2	PS50143
Domain	BIR	BIRC3 BIRC6	2.46e-03	8	179	2	SM00238
Domain	-	BIRC3 BIRC6	2.46e-03	8	179	2	1.10.1170.10
Domain	BIR_rpt	BIRC3 BIRC6	2.46e-03	8	179	2	IPR001370
Domain	BIR_REPEAT_1	BIRC3 BIRC6	2.46e-03	8	179	2	PS01282
Pathway	REACTOME_SIGNALING_BY_WNT	SMURF1 LGR5 TRRAP ARRB2 AP2B1 TLE2 TLE3 TLE4 PRKCG ZRANB1	7.32e-05	239	130	10	MM14756
Pathway	REACTOME_REPRESSION_OF_WNT_TARGET_GENES	TLE2 TLE3 TLE4	8.77e-05	10	130	3	MM15156
Pathway	REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX	TRRAP TLE2 TLE3 TLE4	8.82e-05	26	130	4	MM14793
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	USP53 FUT10 CACNA2D2 RTEL1 SGTA AFF3 SREBF2 SMURF1 WDR27 INTS3 TRRAP TTC19 OPRL1 CUL5 BMPR2 ARRB2 GALNT11 TLE3 EXOC6B KCNMA1 LRP1 ANKIB1 LRRC7 ASPSCR1 GNAS LRBA MCF2L KDM6A ZRANB1 CLBA1 INVS	6.69e-11	1489	184	31	28611215
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	PPP6R1 UNC45A BIRC6 ARRB2 KIF15 N4BP2 TLE3 TLE4 LRP1 ANKRD28 CRYBG3 LRBA L3MBTL3 NPAT	5.85e-08	418	184	14	34709266
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	APPBP2 RIMS3 SMURF1 PPP6R1 TLE3 TLE4 MCM3AP ACIN1 LRRC7 MCF2L SIPA1L2 SLC9A6 PLXNA2	3.03e-07	407	184	13	12693553
Pubmed	The inhibition of differentiation caused by TGFbeta in fetal myoblasts is dependent upon selective expression of PKCtheta: a possible molecular basis for myoblast diversification during limb histogenesis.	MYH1 MYH2 MYH8 PRKCG	5.22e-07	13	184	4	8948582
Pubmed	Evaluation of embryonic and perinatal myosin gene mutations and the etiology of congenital idiopathic clubfoot.	MYH1 MYH2 MYH8	5.80e-07	4	184	3	20357587
Pubmed	TLE expression correlates with mouse embryonic segmentation, neurogenesis, and epithelial determination.	TLE2 TLE3 TLE4	5.80e-07	4	184	3	8645603
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	USP53 KIF13B GRK7 ARHGEF5 UNC45A KLC4 FSIP2 VPS13D BMPR2 MTUS1 N4BP2 PRKCG AKAP11 CRYBG3 GNAS SIPA1L2 KIF13A MUSK	8.49e-07	861	184	18	36931259
Pubmed	Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein.	TLE2 TLE3 TLE4	1.45e-06	5	184	3	8365415
Pubmed	Myosin heavy chain isoforms of the murine masseter muscle during pre- and post-natal development.	MYH1 MYH2 MYH8	1.45e-06	5	184	3	12919077
Pubmed	Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins.	TLE2 TLE3 TLE4	1.45e-06	5	184	3	1303260
Pubmed	Developmental pattern of mouse skeletal myosin heavy chain gene transcripts in vivo and in vitro.	MYH1 MYH2 MYH8	1.45e-06	5	184	3	3829126
Pubmed	The novel function of HINFP as a co-activator in sterol-regulated transcription of PCSK9 in HepG2 cells.	SREBF2 TRRAP NPAT	1.45e-06	5	184	3	22288532
Pubmed	Sequential accumulation of mRNAs encoding different myosin heavy chain isoforms during skeletal muscle development in vivo detected with a recombinant plasmid identified as coding for an adult fast myosin heavy chain from mouse skeletal muscle.	MYH1 MYH2 MYH8	1.45e-06	5	184	3	6196357
Pubmed	Distinct myogenic programs of embryonic and fetal mouse muscle cells: expression of the perinatal myosin heavy chain isoform in vitro.	MYH1 MYH2 MYH8	2.88e-06	6	184	3	1728586
Pubmed	Protein characterization and targeted disruption of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex.	TLE2 TLE3 TLE4	2.88e-06	6	184	3	8573724
Pubmed	Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved.	MYH1 MYH2 MYH8	2.88e-06	6	184	3	10077619
Pubmed	Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development.	MYH1 MYH2 MYH8	2.88e-06	6	184	3	10588881
Pubmed	A Gro/TLE-NuRD corepressor complex facilitates Tbx20-dependent transcriptional repression.	TLE2 TLE3 TLE4	5.02e-06	7	184	3	24024827
Pubmed	A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes.	MYH1 MYH2 MYH8	5.02e-06	7	184	3	35210422
Pubmed	Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.	MYH1 MYH2 MYH8	5.02e-06	7	184	3	16819597
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	USP53 KIF13B MYH2 SGTA PPP6R1 UNC45A TRRAP CUL5 AP2B1 ALDH16A1 EIF4G2 LRP1 MIOS ANKRD28 USP4 LONRF2 ZRANB1 CRTAP	7.28e-06	1005	184	18	19615732
Pubmed	Nolz1 promotes striatal neurogenesis through the regulation of retinoic acid signaling.	TLE2 TLE3 TLE4	8.00e-06	8	184	3	20735826
Pubmed	The Groucho-related gene family regulates the gonadotropin-releasing hormone gene through interaction with the homeodomain proteins MSX1 and OCT1.	TLE2 TLE3 TLE4	8.00e-06	8	184	3	16002402
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	OLAH MYH1 APPBP2 TNPO2 ZBTB41 PPP6R1 BIRC6 AFAP1L2 GALNT11 ALDH16A1 MCM3AP ANP32E LRRC7 ATM LONRF2	9.77e-06	736	184	15	29676528
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	TMEM67 DNAI1 BMPR2 AP2B1 LRP1 LTBP1	1.60e-05	100	184	6	25807483
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	PPP6R1 KANK2 VPS13D MTUS1 ANKRD28 AKAP11 CRYBG3 SIPA1L2	1.68e-05	209	184	8	36779422
Pubmed	Acceleration of somitic myogenesis in embryos of myogenin promoter-MRF4 transgenic mice.	MYH1 MYH2 MYH8	1.70e-05	10	184	3	8950513
Pubmed	Spatial distribution of the full-length members of the Grg family during embryonic neurogenesis reveals a "Grg-mediated repression map" in the mouse telencephalon.	TLE2 TLE3 TLE4	1.70e-05	10	184	3	30571765
Pubmed	Functional proteomics mapping of a human signaling pathway.	SMURF1 RANBP6 UNC45A CUL5 ARRB2 MCM3AP EIF4G2 LRP1 PPP1R37 ANKRD28 KIF13A KDM6A INVS	1.77e-05	591	184	13	15231748
Pubmed	Modulation of contractile protein gene expression in fetal murine crural muscles: emergence of muscle diversity.	MYH1 MYH2 MYH8	2.33e-05	11	184	3	8136524
Pubmed	Coexpression of Cux-1 and Notch signaling pathway components during kidney development.	TLE2 TLE3 TLE4	2.33e-05	11	184	3	15499562
Pubmed	Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development.	MYH1 MYH2 MYH8 FGF6	2.75e-05	33	184	4	32094117
Pubmed	Toll-like receptor 4 (TLR4) is essential for Hsp70-like protein 1 (HSP70L1) to activate dendritic cells and induce Th1 response.	TLR4 HSPA14	2.78e-05	2	184	2	21730052
Pubmed	Myosin heavy chains IIa and IId are functionally distinct in the mouse.	MYH1 MYH2	2.78e-05	2	184	2	9585413
Pubmed	BK Potassium Channels Suppress Cavα2δ Subunit Function to Reduce Inflammatory and Neuropathic Pain.	CACNA2D1 KCNMA1	2.78e-05	2	184	2	29466724
Pubmed	Myosin heavy chain composition of the human genioglossus muscle.	MYH1 MYH2	2.78e-05	2	184	2	22337492
Pubmed	The stem cell-expressed receptor Lgr5 possesses canonical and functionally active molecular determinants critical to β-arrestin-2 recruitment.	LGR5 ARRB2	2.78e-05	2	184	2	24386388
Pubmed	KIF13B enhances the endocytosis of LRP1 by recruiting LRP1 to caveolae.	KIF13B LRP1	2.78e-05	2	184	2	24469637
Pubmed	Dysregulated Smooth Muscle Cell BMPR2-ARRB2 Axis Causes Pulmonary Hypertension.	BMPR2 ARRB2	2.78e-05	2	184	2	36744494
Pubmed	Tamm-Horsfall protein protects the kidney from ischemic injury by decreasing inflammation and altering TLR4 expression.	TLR4 UMOD	2.78e-05	2	184	2	18495803
Pubmed	β-arrestin 2 attenuates lipopolysaccharide-induced liver injury via inhibition of TLR4/NF-κB signaling pathway-mediated inflammation in mice.	ARRB2 TLR4	2.78e-05	2	184	2	29375207
Pubmed	TLE3 and TLE4-coordinated colonic macrophage-CD4+ T cell crosstalk maintains intestinal immune homeostasis.	TLE3 TLE4	2.78e-05	2	184	2	36801171
Pubmed	Phosphorylation of human Rad9 is required for genotoxin-activated checkpoint signaling.	ATM RAD9A	2.78e-05	2	184	2	12709442
Pubmed	ATM mutation rather than BIRC3 deletion and/or mutation predicts reduced survival in 11q-deleted chronic lymphocytic leukemia: data from the UK LRF CLL4 trial.	BIRC3 ATM	2.78e-05	2	184	2	24584352
Pubmed	Plexin/neuropilin complexes mediate repulsion by the axonal guidance signal semaphorin 3A.	PLXNA1 PLXNA2	2.78e-05	2	184	2	10781943
Pubmed	Mutations revealed by sequencing the 5' half of the gene for ataxia telangiectasia.	ATM NPAT	2.78e-05	2	184	2	8789452
Pubmed	The COP II adaptor protein TMED7 is required to initiate and mediate the delivery of TLR4 to the plasma membrane.	TMED7 TLR4	2.78e-05	2	184	2	25074978
Pubmed	Gro/TLE enables embryonic stem cell differentiation by repressing pluripotent gene expression.	TLE3 TLE4	2.78e-05	2	184	2	25446531
Pubmed	Analysis of mouse conceptuses with uniparental duplication/deficiency for distal chromosome 12: comparison with chromosome 12 uniparental disomy and implications for genomic imprinting.	MYH1 MYH2	2.78e-05	2	184	2	16575183
Pubmed	Ataxia-telangiectasia locus: sequence analysis of 184 kb of human genomic DNA containing the entire ATM gene.	ATM NPAT	2.78e-05	2	184	2	9199932
Pubmed	Combined haploinsufficiency for ATM and RAD9 as a factor in cell transformation, apoptosis, and DNA lesion repair dynamics.	ATM RAD9A	2.78e-05	2	184	2	15705893
Pubmed	Small ubiquitin-like modifier modification of arrestin-3 regulates receptor trafficking.	ARRB2 AP2B1	2.78e-05	2	184	2	21118812
Pubmed	Different pathways regulate expression of the skeletal myosin heavy chain genes.	MYH1 MYH2	2.78e-05	2	184	2	11551968
Pubmed	Platelet TLR4-ERK5 Axis Facilitates NET-Mediated Capturing of Circulating Tumor Cells and Distant Metastasis after Surgical Stress.	PADI4 TLR4	2.78e-05	2	184	2	33687949
Pubmed	Differential roles of arrestin-2 interaction with clathrin and adaptor protein 2 in G protein-coupled receptor trafficking.	ARRB2 AP2B1	2.78e-05	2	184	2	12070169
Pubmed	PTPRO Promotes Oxidized Low-Density Lipoprotein Induced Oxidative Stress and Cell Apoptosis through Toll-Like Receptor 4/Nuclear Factor κB Pathway.	PTPRO TLR4	2.78e-05	2	184	2	28578349
Pubmed	Type IIx myosin heavy chain transcripts are expressed in type IIb fibers of human skeletal muscle.	MYH1 MYH2	2.78e-05	2	184	2	7545970
Pubmed	Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle.	SELENOP LRP1	2.78e-05	2	184	2	28263310
Pubmed	Sterol regulatory element-binding protein-2 negatively regulates low density lipoprotein receptor-related protein transcription.	SREBF2 LRP1	2.78e-05	2	184	2	16697011
Pubmed	ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation.	ATM RAD9A	2.78e-05	2	184	2	11278446
Pubmed	Rab40c regulates focal adhesions and PP6 activity by controlling ANKRD28 ubiquitylation.	PPP6R1 CUL5 ANKRD28	3.09e-05	12	184	3	35512830
Pubmed	All Tcf HMG box transcription factors interact with Groucho-related co-repressors.	TLE2 TLE3 TLE4	3.09e-05	12	184	3	11266540
Pubmed	Contractile protein gene expression in primary myotubes of embryonic mouse hindlimb muscles.	MYH1 MYH2 MYH8	4.01e-05	13	184	3	8404542
Pubmed	Neurog2 simultaneously activates and represses alternative gene expression programs in the developing neocortex.	TLE2 TLE3 TLE4	4.01e-05	13	184	3	22735158
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	INTS3 TRRAP BIRC6 HAUS4 N4BP2 SAP30BP INTS4 ACIN1 ANKRD28 L3MBTL3 KDM6A	4.47e-05	469	184	11	27634302
Pubmed	Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet.	TLE2 TLE3 TLE4	5.08e-05	14	184	3	17202186
Pubmed	Defective excitation-contraction coupling is partially responsible for impaired contractility in hindlimb muscles of Stac3 knockout mice.	MYH1 MYH2 MYH8	5.08e-05	14	184	3	27184118
Pubmed	Temporal regulation of the Mediator complex during muscle proliferation, differentiation, regeneration, aging, and disease.	MYH1 MYH2 MYH8 MED10	5.40e-05	39	184	4	38690566
Pubmed	Exome sequencing supports a de novo mutational paradigm for schizophrenia.	TRRAP UGT1A3 SLC26A7 SAP30BP	5.97e-05	40	184	4	21822266
Pubmed	Developmental restriction of Mash-2 expression in trophoblast correlates with potential activation of the notch-2 pathway.	TLE2 TLE3 TLE4	6.33e-05	15	184	3	9291577
Pubmed	TLR2, TLR4 and CD86 gene polymorphisms in recurrent aphthous stomatitis.	CD86 TLR4	8.32e-05	3	184	2	25482673
Pubmed	Molecular determinants of force production in human skeletal muscle fibers: effects of myosin isoform expression and cross-sectional area.	MYH1 MYH2	8.32e-05	3	184	2	25567808
Pubmed	Epithelial expression and chromosomal location of human TLE genes: implications for notch signaling and neoplasia.	TLE2 TLE3	8.32e-05	3	184	2	8808280
Pubmed	A novel regulatory mechanism of the bone morphogenetic protein (BMP) signaling pathway involving the carboxyl-terminal tail domain of BMP type II receptor.	SMURF1 BMPR2	8.32e-05	3	184	2	17576816
Pubmed	TLR4-mediated expulsion of bacteria from infected bladder epithelial cells.	TLR4 RAB27B	8.32e-05	3	184	2	19706440
Pubmed	The expression of myosin heavy chain (MHC) genes in human skeletal muscle is related to metabolic characteristics involved in the pathogenesis of type 2 diabetes.	MYH1 MYH2	8.32e-05	3	184	2	21470888
Pubmed	The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis.	ARRB2 AP2B1	8.32e-05	3	184	2	10097102
Pubmed	Beta-arrestins regulate a Ral-GDS Ral effector pathway that mediates cytoskeletal reorganization.	RALGDS ARRB2	8.32e-05	3	184	2	12105416
Pubmed	Pro-osteogenic phenotype of human aortic valve interstitial cells is associated with higher levels of Toll-like receptors 2 and 4 and enhanced expression of bone morphogenetic protein 2.	BMPR2 TLR4	8.32e-05	3	184	2	19195606
Pubmed	Repulsive and attractive semaphorins cooperate to direct the navigation of cardiac neural crest cells.	PLXNA1 PLXNA2	8.32e-05	3	184	2	18625214
Pubmed	Erythroid differentiation regulator-1 induced by microbiota in early life drives intestinal stem cell proliferation and regeneration.	LGR5 TLR4	8.32e-05	3	184	2	31980634
Pubmed	Differential expression of plexin-A subfamily members in the mouse nervous system.	PLXNA1 PLXNA2	8.32e-05	3	184	2	11241833
Pubmed	Presynaptic α2δ subunits are key organizers of glutamatergic synapses.	CACNA2D1 CACNA2D2	8.32e-05	3	184	2	33782113
Pubmed	β-arrestin 2 regulates Toll-like receptor 4-mediated apoptotic signalling through glycogen synthase kinase-3β.	ARRB2 TLR4	8.32e-05	3	184	2	20497256
Pubmed	Smurf1 aggravates non-alcoholic fatty liver disease by stabilizing SREBP-1c in an E3 activity-independent manner.	SMURF1 FBXW7	8.32e-05	3	184	2	32301540
Pubmed	Analysis of 11q22-q23 deletion target genes in B-cell chronic lymphocytic leukaemia: evidence for a pathogenic role of NPAT, CUL5, and PPP2R1B.	CUL5 NPAT	8.32e-05	3	184	2	17449237
Pubmed	Interaction of PTPRO and TLR4 signaling in hepatocellular carcinoma.	PTPRO TLR4	8.32e-05	3	184	2	25034527
Pubmed	Selective role of sterol regulatory element binding protein isoforms in aggregated LDL-induced vascular low density lipoprotein receptor-related protein-1 expression.	SREBF2 LRP1	8.32e-05	3	184	2	20980003
Pubmed	Structural Basis for Plexin Activation and Regulation.	PLXNA1 PLXNA2	8.32e-05	3	184	2	27397516
Pubmed	Transition of myosin heavy chain isoforms in human laryngeal abductors following denervation.	MYH1 MYH2	8.32e-05	3	184	2	26059207
Pubmed	Increased sensitivity to kindling in mice lacking TSP1.	CACNA2D2 THBS2	8.32e-05	3	184	2	26241338
Pubmed	Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis.	CLTCL1 AP2B1	8.32e-05	3	184	2	19509056
Pubmed	DNMT1 and DNMT3B regulate tumorigenicity of human prostate cancer cells by controlling RAD9 expression through targeted methylation.	RAD9A DNMT3B	8.32e-05	3	184	2	32780107
Pubmed	CD86 stimulation on a B cell activates the phosphatidylinositol 3-kinase/Akt and phospholipase C gamma 2/protein kinase C alpha beta signaling pathways.	CD86 TLR4	8.32e-05	3	184	2	16709832
Pubmed	Fyn-dependent phosphorylation of PlexinA1 and PlexinA2 at conserved tyrosines is essential for zebrafish eye development.	PLXNA1 PLXNA2	8.32e-05	3	184	2	29091353
Pubmed	Plexins promote Hedgehog signaling through their cytoplasmic GAP activity.	PLXNA1 PLXNA2	8.32e-05	3	184	2	36169302
Pubmed	CD44 and TLR4 mediate hyaluronic acid regulation of Lgr5+ stem cell proliferation, crypt fission, and intestinal growth in postnatal and adult mice.	LGR5 TLR4	8.32e-05	3	184	2	26505972
Pubmed	Genetic variants of NPAT-ATM and AURKA are associated with an early adverse reaction in the gastrointestinal tract of patients with cervical cancer treated with pelvic radiation therapy.	ATM NPAT	8.32e-05	3	184	2	21050672
Pubmed	Sepsis induces an increase in thick ascending limb Cox-2 that is TLR4 dependent.	TLR4 UMOD	8.32e-05	3	184	2	17634395
Pubmed	Tle corepressors are differentially partitioned to instruct CD8+ T cell lineage choice and identity.	TLE3 TLE4	8.32e-05	3	184	2	30045946
Interaction	KRT8 interactions	USP53 MYH1 KRT32 PPP6R1 KLC4 BIRC6 HAUS4 KIF15 N4BP2 ANKRD28 AKAP11 USP4 FGD5 CRYBG3 SIPA1L2 ZRANB1	2.49e-06	441	181	16	int:KRT8
GeneFamily	Myosin heavy chains	MYH1 MYH2 MYH8	1.35e-04	15	124	3	1098
GeneFamily	WD repeat domain containing	COP1 WDR27 DNAI1 TLE2 TLE3 TLE4 LRBA FBXW7	4.52e-04	262	124	8	362
GeneFamily	Protein phosphatase 6 regulatory subunits	PPP6R1 ANKRD28	6.87e-04	6	124	2	699
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	SGTA KLC4 TTC1 TTC19 KDM6A	1.18e-03	115	124	5	769
GeneFamily	Ring finger proteins\|Baculoviral IAP repeat containing\|Caspase recruitment domain containing	BIRC3 BIRC6	1.27e-03	8	124	2	419
GeneFamily	Plexins	PLXNA1 PLXNA2	1.63e-03	9	124	2	683
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	AXL NTRK2 MUSK	2.59e-03	40	124	3	321
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTRK2 AFF3 EDNRB BMPR2 TLE4 FGD5 SIPA1L2 KIF13A CD200	1.11e-07	193	183	9	a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AXL KANK2 EDNRB ANOS1 RERGL NT5DC2 LTBP1 ATP1B2	4.28e-07	165	183	8	9de841c1c95967c562720feba930246debc626fd
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AXL KANK2 EDNRB ANOS1 RERGL NT5DC2 LTBP1 ATP1B2	4.28e-07	165	183	8	a612a7d3a5415ecacc3df8fbff0ce498f982aad0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AXL KANK2 EDNRB ANOS1 RERGL NT5DC2 LTBP1 ATP1B2	4.28e-07	165	183	8	cdc94a640ec01c6892521bcd6f0ee0a66ff23866
ToppCell	renal_medulla_nuclei-Adult_normal_reference\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	USP53 PDK4 SREBF2 MTUS1 EXOC6B LTBP1 LRBA PLXNA2	1.24e-06	190	183	8	f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell	facs-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENOP LRRC58 EDNRB BMPR2 HOXD8 EIF4G2 FGD5 PLXNA2	1.51e-06	195	183	8	7f9b7f15006610ad591063d90e90367bd6083c7f
ToppCell	10x5'v1-week_12-13-Myeloid_macrophage-stroma-stromal_macrophage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SELENOP PDK4 AXL FCGBP MTUS1 PTPRO KCNMA1 SIPA1L2	1.63e-06	197	183	8	075044c17f1c52008cd3c292c15cbf485b50411e
ToppCell	VE-mono1-\|VE / Condition, Cell_class and T cell subcluster	SELENOP AXL FCGBP BST1 CD86 TLR4 KCNMA1 LRP1	1.69e-06	198	183	8	2959d6e4992c36040ec9637f5a2daed02b35cf30
ToppCell	VE-mono1\|VE / Condition, Cell_class and T cell subcluster	SELENOP AXL FCGBP BST1 CD86 TLR4 KCNMA1 LRP1	1.69e-06	198	183	8	c742871b8ec4720b1848991551c7c1f4000ebd85
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	SELENOP DDAH1 NTRK2 RFX4 EDNRB ANOS1 LTBP1 ATP1B2	1.82e-06	200	183	8	792fef1f3e47ce5c131fedfad55075fc254aeead
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AXL NTRK2 THBS2 SLC26A7 LTBP1 LRRD1 PLXNA1	6.01e-06	167	183	7	fe3338f99f94c0dac37e3d649dfdce82e4a56022
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|Monocyte / Donor, Lineage, Cell class and subclass (all cells)	CACNA2D2 GRK7 TNPO2 MCM3AP MIPEP PLA2G1B FGD5	6.75e-06	170	183	7	4a19c7e3bb0f9c2601a10debe7000066789b4150
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B RALGDS MUC5B FCGBP BST1 ANKRD28 MCF2L	8.16e-06	175	183	7	31f0fb2e47e357dbf9c15436b7df85b3c370ded7
ToppCell	facs-Aorta\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH8 EDNRB HOXB8 HOXD8 FGD5 LY6E CD200	8.47e-06	176	183	7	0b3491451be02c18a16cdb875645be47eb867a7f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SELENOP LRRC58 EDNRB THBS2 LRP1 LTBP1 ATP1B2	9.80e-06	180	183	7	ea7a1ccf0dd3bb5af5df87501f873e7339a824b3
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA2D1 NTRK2 RERGL LTBP1 TDP1 ATP1B2 LRRD1	9.80e-06	180	183	7	79c5725f02e038d0187f4a1e1591f2492538aa57
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Alv_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTRK2 AFF3 EDNRB BMPR2 TLE4 FGD5 SIPA1L2	9.80e-06	180	183	7	544fb373a3346186ec60afe2cfcf141bb04a1eed
ToppCell	Bronchial_Biopsy-Mesenchymal-Smooth_muscle\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	NTRK2 KANK2 EDNRB THBS2 RERGL LTBP1 ATP1B2	9.80e-06	180	183	7	7085a851807e6a833965e1366946db0bbc5174e2
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2\|TCGA-Skin / Sample_Type by Project: Shred V9	C5orf22 BMPR2 HEATR6 AP2B1 ANKRD28 LRBA MGAT5B	1.02e-05	181	183	7	9d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HENMT1 FCGBP N4BP2 KCNMA1 LY6E MCF2L RAB27B	1.09e-05	183	183	7	5a936fb07074cec753bf19e3e3e52499605ea22c
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HENMT1 FCGBP N4BP2 KCNMA1 LY6E MCF2L RAB27B	1.09e-05	183	183	7	07c18ccc45ddc9c22e482bd9ffb87f46ebcfe473
ToppCell	BAL-Severe-Myeloid-Macrophage\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELENOP PDK4 TDRD1 HOXB8 KCNMA1 FGD5 CRTAP	1.17e-05	185	183	7	ae966929fb5bbb08ffcbac76cb21941638727f55
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SELENOP PDK4 TDRD1 HOXB8 KCNMA1 FGD5 CRTAP	1.17e-05	185	183	7	3beebaa92275086b1fae5f8c0c3d54016c5ba2aa
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELENOP PDK4 TDRD1 HOXB8 KCNMA1 FGD5 CRTAP	1.17e-05	185	183	7	42939b294ea3e871274d8b73124c850dc1904fd2
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELENOP PDK4 TDRD1 HOXB8 KCNMA1 FGD5 CRTAP	1.17e-05	185	183	7	7a3612520ae4f0cd61480eadba31eecce001419d
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SELENOP PDK4 TDRD1 HOXB8 KCNMA1 FGD5 CRTAP	1.17e-05	185	183	7	ceff11cfa679147ccfd0a0f8079e697a6bea34d9
ToppCell	BAL-Severe-Myeloid-Macrophage\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SELENOP PDK4 TDRD1 HOXB8 KCNMA1 FGD5 CRTAP	1.17e-05	185	183	7	9aea5ed8f9cee5ee933891203aac7adb85d68201
ToppCell	Severe_COVID-19-Myeloid-transitional_Macro\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	SELENOP PDK4 TDRD1 HOXB8 KCNMA1 FGD5 CRTAP	1.17e-05	185	183	7	f7ef0d7740b4cfedc38846e802898c402dc411fd
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-1\|TCGA-Breast / Sample_Type by Project: Shred V9	CACNA2D2 AFF3 AP2B1 TLE3 TMEM145 LRBA LONRF2	1.26e-05	187	183	7	a716b64ca03d9b61da765bf87f065ac9393303f1
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CES1 EDNRB THBS2 ANOS1 KCNMA1 LRRC7 LTBP1	1.30e-05	188	183	7	74f7d216209cabdc96b2d46685b0ae017fdcc8fc
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	USP53 PDK4 AXL ARRB2 FCGBP CD86 LY6E	1.30e-05	188	183	7	3f47395db7e6159fc95810545bad4b6e028464c5
ToppCell	Control-Endothelial-Endothelial-Alv_Gen_Intermediate\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTRK2 AFF3 EDNRB TLE4 FGD5 MCF2L SIPA1L2	1.35e-05	189	183	7	5d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTRK2 AFF3 EDNRB BMPR2 TLE4 FGD5 KIF13A	1.39e-05	190	183	7	474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTRK2 AFF3 EDNRB TLE4 FGD5 MCF2L SIPA1L2	1.39e-05	190	183	7	a3c6eec6df052105ab78b7e3c78f94218d5912eb
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-RGCs_early_2\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	SELENOP IRX5 NTRK2 PERP RFX4 EDNRB FZD10	1.44e-05	191	183	7	06107849463a1ccb78a5ccd3ae31619ef6bedda3
ToppCell	renal_papilla_nuclei-Adult_normal_reference\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA2D1 AFF3 SREBF2 EDNRB FCGBP LTBP1 LRBA	1.49e-05	192	183	7	6c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTRK2 AFF3 EDNRB TLE4 FGD5 MCF2L SIPA1L2	1.49e-05	192	183	7	c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCell	LPS-IL1RA+antiTNF-Endothelial\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTRK2 AFF3 EDNRB TLE4 FGD5 MCF2L SIPA1L2	1.49e-05	192	183	7	04f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AFF3 EDNRB TLE4 FGD5 MCF2L SIPA1L2 KIF13A	1.54e-05	193	183	7	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AFF3 EDNRB TLE4 FGD5 MCF2L SIPA1L2 KIF13A	1.54e-05	193	183	7	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DDAH1 NTRK2 EDNRB BMPR2 FGD5 LY6E CD200	1.54e-05	193	183	7	097a244cf37ce6c1ace9bae56beb7de59442cd6b
ToppCell	LPS-IL1RA-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTRK2 AFF3 EDNRB BMPR2 FGD5 MCF2L SIPA1L2	1.59e-05	194	183	7	43f92b0533e26633dc94cce554045d641ef8fd76
ToppCell	PND07-Endothelial-Endothelial_blood-vessel\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DDAH1 NTRK2 EDNRB BMPR2 FGD5 LY6E CD200	1.59e-05	194	183	7	12496bc964d1c572241410524a89ca1a9fdb7e34
ToppCell	LPS-IL1RA-Endothelial-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NTRK2 AFF3 EDNRB BMPR2 FGD5 MCF2L SIPA1L2	1.59e-05	194	183	7	1d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCell	Non-neuronal-Non-dividing\|World / Primary Cells by Cluster	SELENOP DDAH1 AXL EDNRB ANOS1 LTBP1 ATP1B2	1.59e-05	194	183	7	0add09d97192b34bd506209ab5f1a77182f498fc
ToppCell	Bronchial_Biopsy-Immune-Luminal_Macrophages\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	CES1 PDK4 ANOS1 PTPRO BST1 KCNMA1 LRP1	1.65e-05	195	183	7	6800c17026ec6c56132bf4664b8fcd74d7836579
ToppCell	droplet-Mammary_Gland-nan-18m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RALGDS PDK4 DNAI1 FCGBP LY6E RAB27B CD200	1.65e-05	195	183	7	c771ac1db8bd5f3a80bd3484094a58c28983f97b
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B CACNA2D1 ACSL3 THBS2 BMPR2 KCNMA1 LRP1	1.65e-05	195	183	7	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	3'_v3-Lung\|World / Manually curated celltypes from each tissue	PDK4 AXL ANOS1 TLR4 KCNMA1 LRP1 FGD5	1.70e-05	196	183	7	a04f8384b734ce67ec402e64bd891a6274f04744
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AXL AFF3 THBS2 HMCN2 KCNMA1 LRRC7 LTBP1	1.70e-05	196	183	7	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	droplet-Mammary_Gland-nan-18m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RALGDS PDK4 PERP DNAI1 FCGBP RAB27B CD200	1.70e-05	196	183	7	00f9171da4c791619e8c4c8c3c7da578c96a30ed
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AXL AFF3 THBS2 HMCN2 KCNMA1 LRRC7 LTBP1	1.70e-05	196	183	7	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENOP AXL NTRK2 BIRC3 THBS2 KCNMA1 LRP1	1.70e-05	196	183	7	61bee32ca299219f31a30b57124e44e85b798e9f
ToppCell	COPD-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	PDK4 NTRK2 AFF3 ACSL3 BMPR2 MCF2L SIPA1L2	1.76e-05	197	183	7	30dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell	Mesenchymal_cells-Arteriolar_fibro.\|Mesenchymal_cells / Lineage and Cell class	AXL NTRK2 AFF3 THBS2 HMCN2 LRP1 LY6E	1.76e-05	197	183	7	cb321836980e7b4efbb9284c6af7ccd34079d2be
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Macroglial-Astroglia\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	DDAH1 NTRK2 RFX4 EDNRB ANOS1 CTNNA2 ATP1B2	1.82e-05	198	183	7	715ecad21f572b195ff3b78216b1a7b32bbb4ace
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	DDX60 BIRC3 TTC19 TLE4 EIF4G2 ATM LY6E	1.82e-05	198	183	7	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	COVID-19_Mild-Classical_Monocyte\|COVID-19_Mild / Disease condition and Cell class	PADI4 CES1 BST1 TLE3 TLR4 LRP1 KIF13A	1.82e-05	198	183	7	30ada3de865b6fb2b14196a1cbfd4740c6a57ce3
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Macroglial\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	DDAH1 NTRK2 RFX4 EDNRB ANOS1 CTNNA2 ATP1B2	1.82e-05	198	183	7	9d03768f8b6c74e060c5f045508538f9b331f469
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PDK4 RIMS3 EDNRB RERGL KCNMA1 LTBP1 ATP1B2	1.82e-05	198	183	7	1e1ea54f0c234f3b6d29064c4881d8a0c0949a75
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	AFF3 BIRC6 EXOC6B KCNMA1 LRBA KDM6A FBXW7	1.88e-05	199	183	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Type_2_alveolar\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	SELENOP DDAH1 CACNA2D2 PERP MTUS1 PLA2G1B RAB27B	1.88e-05	199	183	7	e28ace2ca680c6154398e17110aa1838dd7a5548
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	SELENOP DDAH1 CACNA2D2 PERP MTUS1 PLA2G1B RAB27B	1.88e-05	199	183	7	e459d5aa63c83f960562be33cea8182b0556eabf
ToppCell	BAL-Severe-cDC_0\|Severe / Compartment, Disease Groups and Clusters	SELENOP PDK4 ANOS1 BST1 TLR4 LRP1 CRTAP	1.88e-05	199	183	7	d39be8b173156bf87baddd3caed4b35597c53ea1
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Macroglial-Astrocyte\|10w / Sample Type, Dataset, Time_group, and Cell type.	SELENOP DDAH1 NTRK2 RFX4 EDNRB FZD10 ATP1B2	1.94e-05	200	183	7	75f5ea38fbd341b80a8058077a04447f0e0eea28
ToppCell	COVID-mono1-\|COVID / Condition, Cell_class and T cell subcluster	SELENOP AXL FCGBP MTUS1 CD86 TLR4 LRP1	1.94e-05	200	183	7	445a1aab962673dcc926c33ce9bed5ede9c41c57
ToppCell	Parenchymal-10x3prime_v2-Stromal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	USP53 CES1 PDK4 AXL KANK2 LRP1 LTBP1	1.94e-05	200	183	7	f6be0f24e607abb9007823a54fb0b24d04990a89
ToppCell	Bronchial-10x5prime-Stromal-Pericyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	RIMS3 KANK2 EDNRB C9orf153 AFAP1L2 NT5DC2 ATP1B2	1.94e-05	200	183	7	362706445edb33b313684efe50b1f44f5f816e67
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Macroglial-Astrocyte\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	DDAH1 NTRK2 RFX4 EDNRB AFAP1L2 LTBP1 ATP1B2	1.94e-05	200	183	7	4fe3b2d80c567c18621bff3341f9a73578c81621
ToppCell	COVID-mono1\|COVID / Condition, Cell_class and T cell subcluster	SELENOP AXL FCGBP MTUS1 CD86 TLR4 LRP1	1.94e-05	200	183	7	bd002c54305c746c07b7418a2084195e9c852ec5
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon-Radial_glial\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	SELENOP DDAH1 EDNRB KIF15 ANP32E LTBP1 ATP1B2	1.94e-05	200	183	7	49197316231e45f8c9f007f55b036600f7195922
ToppCell	severe-HLA-DR-_S100A+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PADI4 CES1 BST1 TLE3 TLR4 LRP1 ANKRD28	1.94e-05	200	183	7	db7046741706376682d164c385c4701aebefc2e6
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon-Radial_glial-RG\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	SELENOP DDAH1 EDNRB KIF15 ANP32E LTBP1 ATP1B2	1.94e-05	200	183	7	dea7928d6ceb7a347f56c6d0c9c7a56b7a2c0a80
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	DDAH1 NTRK2 RFX4 EDNRB ANOS1 LTBP1 ATP1B2	1.94e-05	200	183	7	ed4a41cb6782541d8fc928aaa12cf03bc1c630a2
ToppCell	control-HLA-DR-_S100A+_Monocyte\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PADI4 CES1 BST1 TLR4 LRP1 KIF13A CRTAP	1.94e-05	200	183	7	9e3e13a68bc1110fa000ec2d80f4c654ddbce17e
ToppCell	COVID-19_Convalescent-PLT_3\|World / Disease Group and Platelet Clusters	LRRC58 KANK2 AP2B1 TLR4 LTBP1 ATM	2.20e-05	137	183	6	bb54bb81b450462ad521b57e1a07a80ce1678e67
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Cortical_neuron\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	CACNA2D1 AFF3 PTPRO NEUROD6 PLXNA2 CD200	3.41e-05	148	183	6	a1269312903fc27830c1835dabf660c659a711be
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CLTCL1 LGR5 TLE2 LRRC7 HSPA14 CD200	5.26e-05	160	183	6	5cd4fbbd2ce671a8377416eff94041a111375dee
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MYH2 MED10 DDAH1 TLE4 PRKCG NEUROD6	5.64e-05	162	183	6	4d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AXL PERP BST1 CIDEC TLR4 LRP1	5.64e-05	162	183	6	d712bc31840ad1523e3dbf884acbb428a8995001
ToppCell	E12.5-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SELENOP DNAI1 HOXD8 BTNL2 FGD5 GNAS	5.84e-05	163	183	6	c21114826bee1b05b411984326fef6b6e0d05316
ToppCell	E12.5-Endothelial-lymphatic_endothelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SELENOP DNAI1 HOXD8 BTNL2 FGD5 GNAS	5.84e-05	163	183	6	5d49414432db259a19df50d7944581d00b69f537
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	USP53 PDK4 NTRK2 VPS13D UMOD RP1	5.84e-05	163	183	6	cab65dabeea58141c649e4fec5e0123beb3de1b3
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SELENOP EDNRB THBS2 LRP1 LTBP1 ATP1B2	6.04e-05	164	183	6	01a7c335897128d3478b8b9b44fb461cab493084
ToppCell	droplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RALGDS SELENOP AXL RIMS3 CD86 BTNL2	6.24e-05	165	183	6	6dda1c7fd812792bd2e4fb1a7ccb82a3552b0a3b
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AXL NTRK2 THBS2 SLC26A7 LTBP1 LRRD1	6.24e-05	165	183	6	4e13fccd32029e2879e85f8966e582a46c09e4aa
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CACNA2D2 GRK7 TNPO2 MCM3AP MIPEP PLA2G1B	6.68e-05	167	183	6	dbd2b9f2f4ba7be5fdf8318094e6b078cb1d1c43
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RFX4 SLC26A7 UMOD PRDM14 MUSK	6.68e-05	103	183	5	3f4e4600c8a9af3534479ca19905c3d31c4c55bb
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL RIMS3 CD86 BTNL2 TLR4 PLXNA1	6.90e-05	168	183	6	4ae9e9d93bcd6f4d5815e57fd5afa7a3398a0ec1
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL RIMS3 CD86 BTNL2 TLR4 PLXNA1	6.90e-05	168	183	6	04e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AXL RIMS3 CD86 BTNL2 TLR4 PLXNA1	7.13e-05	169	183	6	454b92b9b67299a64278c010db033ca5b9d217a0
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	ARHGEF5 NTRK2 NPIPA1 MUC5B MTUS1 CD200	7.13e-05	169	183	6	625788d86f0ceebcf2653a251db1f1a9f9746d29
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Efna5_(Deep_layer_pyramidal_cells)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MYH1 MYH2 FTHL17 UMOD	7.15e-05	54	183	4	13431c23a110070a11de41773233a8d6583d902c
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Efna5_(Deep_layer_pyramidal_cells)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MYH1 MYH2 FTHL17 UMOD	7.15e-05	54	183	4	cd64ee5c47df5dba0cea954cb115a8de0efb55d1
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDAH1 NTRK2 WDR27 LRRC9 DNAI1 ATP1B2	7.86e-05	172	183	6	e15ab284df6dd241d4481f98864b18c39d757b8c
ToppCell	Control-MAIT\|Control / Disease group and Cell class	NTRK2 CCNT2 TLE2 ALDH16A1 TLR4 L3MBTL3	7.86e-05	172	183	6	552bc62e8e8bb0ac1cd0452f4410a3af087787eb
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AFF3 THBS2 LRP1 LRRC7 LTBP1 MUSK	8.64e-05	175	183	6	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRSS1 CACNA2D2 PERP LGR5 FCGBP NOTUM	8.64e-05	175	183	6	bffa623511ceb0b9bf76d87f9a10cfadfe0e940f
ToppCell	Thalamus-Neuronal-Excitatory\|Thalamus / BrainAtlas - Mouse McCarroll V32	RIMS3 ACTR1B NAPB KCNMA1 LRRC7 FBXW7	8.92e-05	176	183	6	d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_activate-7\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ARHGEF5 SMURF1 KIF15 NT5DC2 ALDH16A1 CD200	8.92e-05	176	183	6	dde46f06f6fc3f7ba83be91a0ee6231790955e3e
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH1 MYH2 MYH8	2.47e-05	10	177	3	DOID:0111269 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH1 MYH2 MYH8	2.47e-05	10	177	3	DOID:0111602 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH1 MYH2 MYH8	2.47e-05	10	177	3	DOID:0111596 (implicated_via_orthology)
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH1 MYH2 MYH8	2.47e-05	10	177	3	DOID:0110454 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH1 MYH2 MYH8	2.47e-05	10	177	3	DOID:0080719 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH1 MYH2 MYH8	2.47e-05	10	177	3	DOID:3429 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH1 MYH2 MYH8	2.47e-05	10	177	3	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH1 MYH2 MYH8	2.47e-05	10	177	3	DOID:0080326 (implicated_via_orthology)
Disease	distal myopathy (implicated_via_orthology)	MYH1 MYH2 MYH8	4.49e-05	12	177	3	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH1 MYH2 MYH8	4.49e-05	12	177	3	DOID:2106 (implicated_via_orthology)
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH1 MYH2 MYH8	5.81e-05	13	177	3	DOID:397 (implicated_via_orthology)
Disease	distal arthrogryposis (implicated_via_orthology)	MYH1 MYH2 MYH8	9.16e-05	15	177	3	DOID:0050646 (implicated_via_orthology)
Disease	lysophosphatidylcholine 22:6 measurement	CACNA2D1 SIPA1L2 MUSK	1.62e-04	18	177	3	EFO_0010365
Disease	Glioma	RTEL1 NTRK2 ATM ATP1B2 FBXW7	1.82e-04	87	177	5	C0017638
Disease	anorectal malformation	RTEL1 MUC5B THBS2	1.92e-04	19	177	3	MONDO_0019938
Disease	palmitoleoyl-protein carboxylesterase NOTUM measurement	NOTUM ASPSCR1	2.13e-04	4	177	2	EFO_0802842
Disease	Uveal Melanoma	CACNA2D1 AP2B1 TDP1 RAB27B	2.91e-04	53	177	4	EFO_1000616
Disease	Schizophrenia	NTRK2 RIMS3 SREBF2 TRRAP UGT1A3 SLC26A7 TLR4 SAP30BP LRP1 PLA2G1B ATM CTNNA2 GNAS PLXNA2 DNMT3B	2.99e-04	883	177	15	C0036341
Disease	Diffuse interstitial pulmonary fibrosis	RTEL1 MUC5B	5.28e-04	6	177	2	cv:C0085786
Disease	lung small cell carcinoma (is_implicated_in)	ATM KDM6A DNMT3B	6.23e-04	28	177	3	DOID:5409 (is_implicated_in)
Disease	lung adenocarcinoma	RTEL1 MTUS1 TLE3 BTNL2 ATM MUSK	6.58e-04	174	177	6	EFO_0000571
Disease	Malignant Glioma	RTEL1 NTRK2 ATP1B2 FBXW7	8.43e-04	70	177	4	C0555198
Disease	mixed gliomas	RTEL1 NTRK2 ATP1B2 FBXW7	8.43e-04	70	177	4	C0259783
Disease	cardiomyopathy (implicated_via_orthology)	MYH1 MYH2 MYH8 LRP1	8.89e-04	71	177	4	DOID:0050700 (implicated_via_orthology)
Disease	female breast cancer (is_implicated_in)	RTEL1 ATM	9.78e-04	8	177	2	DOID:0050671 (is_implicated_in)
Disease	Colorectal Carcinoma	RALGDS PRSS1 SELENOP LGR5 MCM3AP TLR4 LRP1 ACIN1 GNAS LONRF2 KDM6A FBXW7	1.14e-03	702	177	12	C0009402
Disease	alcohol use disorder (implicated_via_orthology)	GRK7 SREBF2 OPRL1 KCNMA1 PRKCG KDM6A	1.19e-03	195	177	6	DOID:1574 (implicated_via_orthology)
Disease	Nephronophthisis	TMEM67 INVS	1.25e-03	9	177	2	cv:C0687120
Disease	Mammary Carcinoma, Human	SREBF2 EDNRB CUL5 BMPR2 TLE3 FGD5 ATM L3MBTL3 DNMT3B FBXW7	1.33e-03	525	177	10	C4704874
Disease	Mammary Neoplasms, Human	SREBF2 EDNRB CUL5 BMPR2 TLE3 FGD5 ATM L3MBTL3 DNMT3B FBXW7	1.33e-03	525	177	10	C1257931
Disease	Mammary Neoplasms	SREBF2 EDNRB CUL5 BMPR2 TLE3 FGD5 ATM L3MBTL3 DNMT3B FBXW7	1.37e-03	527	177	10	C1458155
Disease	otitis media (is_marker_for)	MUC5B TLR4	1.56e-03	10	177	2	DOID:10754 (is_marker_for)
Disease	Breast Carcinoma	SREBF2 EDNRB CUL5 BMPR2 TLE3 FGD5 ATM L3MBTL3 DNMT3B FBXW7	1.60e-03	538	177	10	C0678222
Disease	Inherited neuropathies	PRKCG ATM TDP1	1.78e-03	40	177	3	C0598589
Disease	Pulmonary Hypertension	EDNRB BMPR2 KCNMA1	1.78e-03	40	177	3	C0020542
Disease	alanine measurement	CLTCL1 PDK4 ACSL3 MIPEP	1.81e-03	86	177	4	EFO_0009765
Disease	Cystic Kidney Diseases	TMEM67 UMOD	1.90e-03	11	177	2	C1691228
Disease	cholelithiasis	UGT1A3 LRBA MUSK VPS37D	1.97e-03	88	177	4	EFO_0004799
Disease	Multiple Myeloma	BIRC3 CD86 KDM6A	2.05e-03	42	177	3	C0026764
Disease	Malignant neoplasm of breast	MYH1 SREBF2 EDNRB CUL5 BMPR2 N4BP2 TLE3 LRRC7 FGD5 ATM LRBA L3MBTL3 HSPA14 DNMT3B FBXW7	2.14e-03	1074	177	15	C0006142
Disease	gallbladder carcinoma (is_marker_for)	BIRC3 MTUS1	2.27e-03	12	177	2	DOID:4948 (is_marker_for)
Disease	Gastric Adenocarcinoma	AXL TRRAP ATM	2.50e-03	45	177	3	C0278701
Disease	phosphatidylcholine 40:7 measurement	NPIPA1 MUSK	2.67e-03	13	177	2	EFO_0021477
Disease	autoimmune thrombocytopenic purpura (is_marker_for)	CD86 DNMT3B	2.67e-03	13	177	2	DOID:8924 (is_marker_for)
Disease	Nephronophthisis	TMEM67 INVS	2.67e-03	13	177	2	C0687120
Disease	amino acid measurement	CACNA2D1 SELENOP MED10 CLTCL1 SMURF1 CCNT2 RERGL KCNMA1 LTBP1 LRBA PLXNA2	2.73e-03	678	177	11	EFO_0005134
Disease	myopathy (implicated_via_orthology)	MYH1 MYH2 MYH8	3.01e-03	48	177	3	DOID:423 (implicated_via_orthology)
Disease	Carcinomatosis	SELENOP PADI4 TLE4 TLR4 DNMT3B	3.09e-03	163	177	5	C0205699
Disease	Carcinoma, Spindle-Cell	SELENOP PADI4 TLE4 TLR4 DNMT3B	3.09e-03	163	177	5	C0205697
Disease	Undifferentiated carcinoma	SELENOP PADI4 TLE4 TLR4 DNMT3B	3.09e-03	163	177	5	C0205698
Disease	Anaplastic carcinoma	SELENOP PADI4 TLE4 TLR4 DNMT3B	3.09e-03	163	177	5	C0205696
Disease	epilepsy (implicated_via_orthology)	CACNA2D2 NUS1 KCNMA1 LRP1 ATP1B2	3.09e-03	163	177	5	DOID:1826 (implicated_via_orthology)
Disease	Hamman-Rich syndrome	RTEL1 MUC5B	3.11e-03	14	177	2	C0085786
Disease	Carcinoma	SELENOP PADI4 TLE4 TLR4 DNMT3B	3.17e-03	164	177	5	C0007097
Disease	Medulloblastoma	ATM L3MBTL3 KDM6A	3.38e-03	50	177	3	C0025149
Disease	omega-6:omega-3 polyunsaturated fatty acid ratio	MAU2 MUSK VPS37D	3.38e-03	50	177	3	EFO_0010732
Disease	Neoplasm of uncertain or unknown behavior of bladder	ATM KDM6A	3.57e-03	15	177	2	C0496930
Disease	autoimmune thrombocytopenic purpura (is_implicated_in)	CD86 DNMT3B	3.57e-03	15	177	2	DOID:8924 (is_implicated_in)
Disease	Benign neoplasm of bladder	ATM KDM6A	3.57e-03	15	177	2	C0154017
Disease	Carcinoma in situ of bladder	ATM KDM6A	3.57e-03	15	177	2	C0154091
Disease	colorectal cancer	SLC6A18 CACNA2D1 RTEL1 RANBP6 UNC45A HDDC3 ACTR1B LRP1 GNAS LRBA	3.66e-03	604	177	10	MONDO_0005575
Disease	level of triacylglycerol (56:6) in blood serum	MAU2 MUSK	4.06e-03	16	177	2	OBA_2020007
Disease	Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	BIRC3 ATM	4.06e-03	16	177	2	C0334634
Disease	migraine without aura, susceptibility to, 4	LRP1 FGF6	4.06e-03	16	177	2	MONDO_0011847
Disease	clonal hematopoiesis mutation measurement	COP1 SAP30BP MIPEP	4.43e-03	55	177	3	EFO_0020949
Disease	idiopathic pulmonary fibrosis	RTEL1 MUC5B KIF15	4.90e-03	57	177	3	EFO_0000768
Disease	non-alcoholic fatty liver disease	MAU2 BTNL2 KCNMA1 L3MBTL3 VPS37D	4.92e-03	182	177	5	EFO_0003095
Disease	bipolar disorder, sex interaction measurement	TLE4 SIPA1L2	5.14e-03	18	177	2	EFO_0008343, MONDO_0004985
Disease	sinusitis (is_marker_for)	MUC5B TLR4	5.14e-03	18	177	2	DOID:0050127 (is_marker_for)
Disease	Carcinoma of bladder	ATM KDM6A	5.14e-03	18	177	2	C0699885
Disease	Withdrawal Symptoms	SMURF1 OPRL1 GNAS	5.14e-03	58	177	3	C0087169
Disease	urate measurement, spine bone mineral density	CACNA2D1 UGT1A3 LTBP1	5.14e-03	58	177	3	EFO_0004531, EFO_0007701
Disease	Drug Withdrawal Symptoms	SMURF1 OPRL1 GNAS	5.14e-03	58	177	3	C0086189
Disease	Substance Withdrawal Syndrome	SMURF1 OPRL1 GNAS	5.14e-03	58	177	3	C0038587
Disease	Cocaine-Related Disorders	CES1 NTRK2 SMURF1 LRRC7	5.48e-03	117	177	4	C0236736
Disease	Insulin Resistance	SELENOP SREBF2 GNAS	5.65e-03	60	177	3	C0021655
Disease	Insulin Sensitivity	SELENOP SREBF2 GNAS	5.65e-03	60	177	3	C0920563
Disease	Usual Interstitial Pneumonia	RTEL1 MUC5B	5.72e-03	19	177	2	C4721509
Disease	Hamman-Rich Disease	RTEL1 MUC5B	5.72e-03	19	177	2	C4721508
Disease	Intellectual Disability	RALGDS AFF3 TRRAP NXF5 ACIN1 PRKCG CTNNA2 GNAS	5.76e-03	447	177	8	C3714756
Disease	Hypertensive disease	SLC6A18 CACNA2D1 TLR4 UMOD GNAS	5.89e-03	190	177	5	C0020538

Protein segments in the cluster

Peptide	Gene	Start	Entry
AELQASLSKYCDQLP	TDRD1	521	Q9BXT4
CANRKPLSQEFEAYI	UGT1A3	281	P35503
QSNPKFLCADYAEQD	ACIN1	1076	Q9UKV3
PNATPEDKQLAALCY	AFF3	1051	P51826
LAPLCNGLINSYEDK	COP1	116	Q8NHY2
ENIPLKLSEDCLYLN	CES1	106	P23141
CAEYRALLSPEQRNK	BST1	51	Q10588
NPCEYDLKFQRSVLD	ASPSCR1	46	Q9BZE9
PLLDTKCDAYLQQTQ	CCNT2	116	O60583
FILDCLSNYNPKDDR	AP2B1	221	P63010
NPNLYNDGKVCLSIL	BIRC6	4656	Q9NR09
RESYVNLCSNPEDKL	CUL5	181	Q93034
NLCSNPEDKLQIYRD	CUL5	186	Q93034
LLSNSELAETCQPYK	CXorf66	256	Q5JRM2
IAPREYCKDLNASDN	CACNA2D2	686	Q9NY47
NCQAELSPAASKYED	CRYBG3	906	Q68DQ2
CNDLSNVNPARKGLY	DNMT3B	651	Q9UBC3
PARLSCLSKNLNYDT	ALDH16A1	491	Q8IZ83
EDIQLTCYLSPKANA	BTNL2	261	Q9UIR0
PSQVRQKYDTNCDAA	FTHL17	6	Q9BXU8
EECPAASLLQKYTNN	BCORP1	81	Q8N888
QCLRAYKPRENDELA	ARHGEF5	1516	Q12774
ECKFRETLLPNNYNA	FGF6	156	P10767
ACYLSINPQKDEALE	ACTR1B	221	P42025
NCQKPDIAEKYLSAS	AFAP1L2	291	Q8N4X5
KCLEYLLRNDANPGI	ANKRD28	486	O15084
KCPFIENQLQDTSRY	BIRC3	231	Q13489
CQIYENNPQLKESLD	ANKIB1	21	Q9P2G1
KNQTCERTLDPYRNE	AKAP11	1436	Q9UKA4
KLTLYNQNDPNRCEL	EDNRB	346	P24530
QQANKAALYGELCAL	APPBP2	201	Q92624
EVLAEKCPNLTYLNL	ANP32E	81	Q9BTT0
DLAINKYEAICNQPV	DNAI1	611	Q9UI46
TNYDKNRLCPSLIQE	DUS3L	116	Q96G46
LKIQAYFNETADLPC	CD86	26	P42081
STAQYKCPVAQLEQD	ARRB2	246	P32121
KLPTSEALLDYQCQI	CCDC83	21	Q8IWF9
ALLELDPKYANQTCG	MUC5B	191	Q9HC84
AYCENPDIVLIGNKA	RAB27B	121	O00194
YQAATPGQDLLRCKI	RAD9A	61	Q99638
YLDFCEKNDTQPVNA	RFX4	86	Q33E94
ANDALNAYVCKGLPQ	INTS3	71	Q68E01
PAQAQKCYRDLALVS	INTS3	101	Q68E01
IDLCKATSPADALQY	INTS4	41	Q96HW7
RSQSQLDLCKDSPYE	IRX5	461	P78411
SADDNLKTPAECLLY	NPIPA1	281	Q9UND3
ANCPYSEINLNKDRI	L3MBTL3	581	Q96JM7
CLKDLCLNDPQYTTN	LRRC9	191	Q6ZRR7
FCTSYQNDDPLNALK	NPAT	386	Q14207
YKDACTVDPVTNQNL	PDK4	141	Q16654
YLLEKGADLNAQTCN	ANKRD53	196	Q8N9V6
PNVARTKNNLASCYL	KLC4	376	Q9NSK0
LASPRSCYKLFQEQQ	PADI4	491	Q9UM07
QNSVILEKLQPDCDY	ANOS1	356	P23352
NLEYNQLTTFPKALC	LRRD1	286	A4D1F6
ACLILANKYCADPDA	KCNMA1	486	Q12791
LLESKACLQDSYDNL	KIF15	856	Q9NS87
QQEAELVQYPDCKSS	HOXD8	151	P13378
KPNDNLNCAGYCDAL	MTUS1	141	Q9ULD2
FNCQALRKLSIPDND	LRRC7	66	Q96NW7
QRALLGYADNQCKLE	GLOD4	186	Q9HC38
RKNPALCFLYDQSNS	ERVFC1-1	116	P60608
DVNECLQLPKACAYQ	HMCN2	4756	Q8NDA2
VEGYLLQPDNRSCKA	LRP1	176	Q07954
PYNDSIQAQKNDVCR	ATP1B2	116	P14415
ADKLYNLRDLNRCTP	HDDC3	121	Q8N4P3
YRSLLENEDCKLPCN	KRT32	396	Q14532
AIQCKNIPDYLNDRT	MCM3AP	436	O60318
NQPQDAIKCYLNATR	KDM6A	366	O15550
EESYINFLAINQKCP	DDX55	376	Q8NHQ9
KNLEIPQDCTYADQK	DDX60	1216	Q8IY21
IPELENCKQNDSIFY	FSIP2	2286	Q5CZC0
QECYLQKEPLLFSCA	MGAT5B	751	Q3V5L5
QSLNSADLLKALCYP	MYH8	391	P13535
NIQAHLYKCPALRES	PLXNA1	801	Q9UIW2
EYKTLILNCVNPDNE	PLXNA2	1496	O75051
YNLNDASLCDNVLAP	LTBP1	1351	Q14766
QCALCPLKDSDDYAQ	LTBP1	1561	Q14766
LCNNKLYQLDGLSDI	NXF5	166	Q9H1B4
QSLNSADLLKALCYP	MYH2	391	Q9UKX2
CCLPNYEDDLLGNAK	PERP	171	Q96FX8
YLNDSLNKCSNGRLP	FGD5	26	Q6ZNL6
LVVLKACDYSDPNQI	GALNT11	506	Q8NCW6
QQELLGLDCSKYSPE	NUS1	156	Q96E22
KCLANLVSNAPYDRL	HEATR6	541	Q6AI08
LSLCYFNPKNSDEQK	LRBA	871	P50851
YNVPVADADNCSLLQ	PRKCG	286	P05129
CSLLQKFEACNYPLE	PRKCG	296	P05129
QNLNSADLLKALCYP	MYH1	391	P12882
KEFLYCLALNPECNS	LONRF2	286	Q1L5Z9
YCSDPNLVLDLKNLI	EXOC6B	391	Q9Y2D4
NPQLYTKECLERALA	MED10	76	Q9BTT4
SADDNLKTPAECLLY	NPIPA3	281	F8WFD2
LYAQLCLRLAEDAPN	EIF4G2	131	P78344
QLCKEQYADPFALAQ	INSM2	266	Q96T92
GNLPSLNYLVLCDNK	LRRC58	186	Q96CX6
AADLPLNRCKNRYTN	PTPRO	956	Q16827
EQLYTPASLKCSLQN	CD200	41	P41217
SCLQYLDARNTPLLD	PPP1R37	191	O75864
DPDLVQYADCKLAAA	HOXB8	101	P17481
SLYPCSAQQLNEDLR	NOTUM	76	Q6P988
SLDCRKLPNKNDPNY	FZD10	131	Q9ULW2
KPLSNVCSLYRRDQD	ATM	971	Q13315
LLAYPKLNRLCANEE	HENMT1	346	Q5T8I9
CPDSACKQDLLAYLQ	CTNNA2	766	P26232
IAPRDYCNDLKISDN	CACNA2D1	661	P54289
LCGNYNQDPADDLKA	FCGBP	3411	Q9Y6R7
YKLNDLKNAAPCAVS	CRTAP	306	O75718
PCAVSYLLFDQNDKV	CRTAP	316	O75718
DSYGECLRNKDLPQQ	FUT10	241	Q6P4F1
DCLADVDTKPAYQNL	BOD1	71	Q96IK1
PYKLCNNQEENDAVS	C5orf22	161	Q49AR2
CSLPELYACIENFNK	C9orf153	21	Q5TBE3
LEPKDLLQAAQTCRY	FBXW7	296	Q969H0
DCSPNKNRYLNVVLN	REXO1L1P	331	Q8IX06
ASQNQERLCAFKDPY	BMPR2	26	Q13873
KQADYVPSDQDLLRC	GNAS	186	P63092
KLLQSACNNYSIAPD	RALGDS	606	Q12967
SNLYCLKPTICSDQD	LY6E	31	Q16553
YLLASQPVDKCQSQD	MCF2L	476	O15068
SACLALEKYLDNPNA	KANK2	596	Q63ZY3
RNPLCNLLSFTYKLD	CENPO	211	Q9BU64
PCNLSKEDLLQNPYF	HAUS4	26	Q9H6D7
IANTAYLQARKPSDC	GRK7	11	Q8WTQ7
RNENIFNCLYKNPEA	OLAH	11	Q9NV23
LYCQENSVDAAKPLL	MAU2	116	Q9Y6X3
DDIAANCIYLNIPNK	DDAH1	216	O94760
YNLLEDLPSFSVCQK	LGR5	361	O75473
SDPQAQKYIAESKCL	HSPA14	76	Q0VDF9
SCNNGYLDAIKLLLD	INVS	496	Q9Y283
EELTQPLELKCNYFN	RP1	1806	P56715
PEKCDNNQYFDISAL	TMEM67	46	Q5HYA8
NSCLNPILYAFLDEN	OPRL1	311	P41146
KCYLVNLNADPALNE	KIF13A	446	Q9H1H9
DKCFLVNLNADPALN	KIF13B	446	Q9NQT8
CSQLLAALTAYKQDD	RTEL1	1076	Q9NZ71
QLNLEIYDPCSQTQK	RERGL	51	Q9H628
CLTSPQAYENQEQLK	SLC9A6	571	Q92581
SYVNCARFPKEQNLV	PRDM14	326	Q9GZV8
KAIELNPANAVYFCN	SGTA	116	O43765
KTCDPLYQQALLFDE	RIMS3	216	Q9UJD0
KSNDLVLSCPYFRNE	SIPA1L2	401	Q9P2F8
DRNAAICFSKAPYNK	PLA2G1B	121	P04054
NETINYEDPCAKRLA	RANBP6	1056	O60518
QASUYLCILQASKLE	SELENOP	56	P49908
TGYQRLDLCKLNPSD	SMURF1	111	Q9HCE7
ASYNSPRNDCQKDAV	SLC6A18	276	Q96N87
LKNLPLVDNICAYAN	ACSL3	601	O95573
DLYKLNPQDFIGCLN	CIDEC	146	Q96AQ7
KIYIDSNNSPECFLR	CLTCL1	881	P53675
EPILSYENILKCAFQ	CLBA1	141	Q96F83
TQDLYCLNESSKNIP	NTRK2	171	Q16620
LLQAANTTDDYRKCP	USP53	211	Q70EK8
DACARYLLFSKQPSQ	TTC19	241	Q6DKK2
QAKPYENISLCQAKL	TDP1	241	Q9NUW8
YLLELKLCENSDPTN	USP4	136	Q13107
DLNIKINFACSYPLD	UMOD	416	P07911
KPLYELGQNDACLSL	MIOS	176	Q9NXC5
FLYPNAGQLKCLEEL	MIPEP	271	Q99797
KSPVSQLDCLNRDNY	TLE4	521	Q04727
ELLPQLCNLLNSEDY	TNPO2	126	O14787
YLNDDRQKQPSFCDL	ZBTB41	76	Q5SVQ8
AKESLYCAQRNPADP	SREBF2	781	Q12772
LPDNAKQCFYEDIAQ	TMED7	41	Q9Y3B3
NRLKQPADCLDGLYA	AXL	766	P30530
AYKKADPQEAINCLN	NAPB	91	Q9H115
ACLASNYALAKENLA	VPS37D	56	Q86XT2
EVCSLLNPAAIYANN	NT5DC2	46	Q9H857
NRNNYASVECGAKIL	SUCO	306	Q9UBS9
NPSIYEKLIQFCAID	SAP30BP	161	Q9UHR5
SPISQLDCLNRDNYI	TLE3	521	Q04726
DENPNANLLEICYKD	PPP6R1	601	Q9UPN7
YRNLASVADQLCKPN	ZNF333	236	Q96JL9
SVADQLCKPNALSYL	ZNF333	241	Q96JL9
LDAPVLSQAKCEASY	PRSS1	161	P07477
CQLLFNPRQADYDKD	THBS2	756	P35442
NKVNPLLICSASLDY	WDR27	81	A2RRH5
ASQSCPNEKCYLILD	SLC26A7	561	Q8TE54
NDCSKAIQLNPSYIR	TTC1	176	Q99614
KTPVAQLDCLNRDNY	TLE2	491	Q04725
NRDNYIRSCKLLPDG	TLE2	501	Q04725
DTFPYKCLNSLQVLD	TLR4	536	O00206
NALAACNYLPQSREK	TRRAP	1371	Q9Y4A5
ACLDKAVEYGLIQPN	UNC45A	926	Q9H3U1
PCEEYNDRNKLNTRT	ZRANB1	136	Q9UGI0
AKCCQNILLYFDDPS	TMEM145	66	Q8NBT3
ARDKPYNCQISHLLE	ZNF662	411	Q6ZS27
LLFCYADKEQPNLCT	VPS13D	3321	Q5THJ4
ACARLPHLDYNKENL	MUSK	446	O15146
CFIKDNTLALESNYP	N4BP2	226	Q86UW6
NDALDNLRKVVPCYS	NEUROD6	111	Q96NK8