Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCC3 ABCB5 ABCB1 ABCG4 ABCD3 ABCG8	3.14e-06	49	166	6	GO:0140359
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCC3 ATP7A ABCB5 ABCB1 ABCG4 ABCD3 ABCG8 ATP5F1B	3.59e-06	109	166	8	GO:0042626
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCC3 ATP7A ABCB5 ATP10B RUVBL2 DDX6 ABCB1 ABCG4 FBH1 ABCD3 ASCC3 DNAH5 ABCG8 RAD54L ATP5F1B	4.36e-06	441	166	15	GO:0016887
GeneOntologyMolecularFunction	ATP-dependent activity	DNHD1 ABCC3 ATP7A ABCB5 ATP10B RUVBL2 DDX6 ABCB1 ACSL1 ABCG4 FBH1 ABCD3 ASCC3 DNAH5 ABCG8 RAD54L ATP5F1B	1.49e-05	614	166	17	GO:0140657
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	ABCC3 ATP7A ABCB5 ATP10B ARL9 RUVBL2 DDX6 ABCB1 ABCG4 FBH1 ABCD3 GNAT3 ASCC3 DNM1 DNAH5 RAB13 ABCG8 RAD54L ATP5F1B	2.51e-05	775	166	19	GO:0017111
GeneOntologyMolecularFunction	lipid transporter activity	ABCC3 ESYT1 ATP10B ANO8 ABCB1 ABCG4 ABCD3 PLSCR3 ABCG8	3.96e-05	196	166	9	GO:0005319
GeneOntologyMolecularFunction	transporter activity	CACNA1C ABCC3 ATP7A TRPM7 ESYT1 ABCB5 ATP10B GRIK4 OCA2 SLC39A10 TMC3 SLC25A51 ANO8 ABCB1 SLC52A3 ABCG4 SLC7A1 SLC16A4 CLCNKA CLCNKB ABCD3 SLC25A52 PLSCR3 ABCG8 ATP5F1B	6.43e-05	1289	166	25	GO:0005215
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	GLUD1 GLUD2	6.87e-05	2	166	2	GO:0016639
GeneOntologyMolecularFunction	glutamate dehydrogenase [NAD(P)+] activity	GLUD1 GLUD2	6.87e-05	2	166	2	GO:0004353
GeneOntologyMolecularFunction	glutamate dehydrogenase (NAD+) activity	GLUD1 GLUD2	6.87e-05	2	166	2	GO:0004352
GeneOntologyMolecularFunction	glutamate dehydrogenase (NADP+) activity	GLUD1 GLUD2	6.87e-05	2	166	2	GO:0004354
GeneOntologyMolecularFunction	pyrophosphatase activity	ABCC3 ATP7A ABCB5 ATP10B ARL9 RUVBL2 DDX6 ABCB1 ABCG4 FBH1 ABCD3 GNAT3 ASCC3 DNM1 DNAH5 RAB13 ABCG8 RAD54L ATP5F1B	7.30e-05	839	166	19	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	ABCC3 ATP7A ABCB5 ATP10B ARL9 RUVBL2 DDX6 ABCB1 ABCG4 FBH1 ABCD3 GNAT3 ASCC3 DNM1 DNAH5 RAB13 ABCG8 RAD54L ATP5F1B	7.41e-05	840	166	19	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	ABCC3 ATP7A ABCB5 ATP10B ARL9 RUVBL2 DDX6 ABCB1 ABCG4 FBH1 ABCD3 GNAT3 ASCC3 DNM1 DNAH5 RAB13 ABCG8 RAD54L ATP5F1B	7.41e-05	840	166	19	GO:0016818
GeneOntologyMolecularFunction	semaphorin receptor activity	PLXNA3 PLXNA4 PLXNA1	1.17e-04	12	166	3	GO:0017154
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ABCC3 ATP7A ABCB5 ABCB1 ABCG4 ABCD3 ABCG8 ATP5F1B	1.24e-04	178	166	8	GO:0015399
GeneOntologyMolecularFunction	1-phosphatidylinositol-5-phosphate 4-kinase activity	PIP4K2B PIP4K2C	2.05e-04	3	166	2	GO:0016309
GeneOntologyMolecularFunction	ABC-type xenobiotic transporter activity	ABCC3 ABCB5 ABCB1	2.39e-04	15	166	3	GO:0008559
GeneOntologyMolecularFunction	transmembrane transporter activity	CACNA1C ABCC3 ATP7A TRPM7 ABCB5 GRIK4 OCA2 SLC39A10 TMC3 SLC25A51 ANO8 ABCB1 SLC52A3 ABCG4 SLC7A1 SLC16A4 CLCNKA CLCNKB ABCD3 SLC25A52 ABCG8 ATP5F1B	3.20e-04	1180	166	22	GO:0022857
GeneOntologyMolecularFunction	phospholipid transporter activity	ESYT1 ATP10B ANO8 ABCB1 PLSCR3	3.79e-04	74	166	5	GO:0005548
GeneOntologyMolecularFunction	NAD+ binding	GLUD1 GLUD2 HADHA	5.80e-04	20	166	3	GO:0070403
GeneOntologyMolecularFunction	ADP binding	RUVBL2 GLUD1 GLUD2 ATP5F1B	6.74e-04	48	166	4	GO:0043531
GeneOntologyMolecularFunction	NAD transmembrane transporter activity	SLC25A51 SLC25A52	6.76e-04	5	166	2	GO:0051724
GeneOntologyMolecularFunction	activin receptor activity, type I	ACVR1B TGFBR1	6.76e-04	5	166	2	GO:0016361
GeneOntologyMolecularFunction	DNA translocase activity	FBH1 RAD54L	6.76e-04	5	166	2	GO:0015616
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ATP10B ANO8 ABCB1 PLSCR3	8.49e-04	51	166	4	GO:0140303
GeneOntologyMolecularFunction	L-leucine binding	GLUD1 GLUD2	1.40e-03	7	166	2	GO:0070728
GeneOntologyMolecularFunction	ATPase-coupled lipid transmembrane transporter activity	ABCC3 ABCG4	2.38e-03	9	166	2	GO:0034040
GeneOntologyMolecularFunction	1-phosphatidylinositol-4-phosphate 5-kinase activity	PIP4K2B PIP4K2C	2.38e-03	9	166	2	GO:0016308
GeneOntologyMolecularFunction	activin receptor activity	ACVR1B TGFBR1	2.38e-03	9	166	2	GO:0017002
GeneOntologyCellularComponent	semaphorin receptor complex	PLXNA3 PLXNA4 PLXNA1	1.40e-04	13	169	3	GO:0002116
GeneOntologyCellularComponent	nuclear pore inner ring	NUP205 NUP155	1.94e-04	3	169	2	GO:0044611
Domain	ABC_transporter_CS	ABCC3 ABCB5 ABCB1 ABCG4 ABCD3 ABCG8	2.01e-06	42	169	6	IPR017871
Domain	ABC_tran	ABCC3 ABCB5 ABCB1 ABCG4 ABCD3 ABCG8	4.50e-06	48	169	6	PF00005
Domain	ABC_TRANSPORTER_2	ABCC3 ABCB5 ABCB1 ABCG4 ABCD3 ABCG8	4.50e-06	48	169	6	PS50893
Domain	ABC_TRANSPORTER_1	ABCC3 ABCB5 ABCB1 ABCG4 ABCD3 ABCG8	5.09e-06	49	169	6	PS00211
Domain	ABC_transporter-like	ABCC3 ABCB5 ABCB1 ABCG4 ABCD3 ABCG8	5.74e-06	50	169	6	IPR003439
Domain	AAA	ABCC3 ABCB5 RUVBL2 ABCB1 ABCG4 ABCD3 ASCC3 DNAH5 ATP5F1B	6.57e-06	144	169	9	SM00382
Domain	AAA+_ATPase	ABCC3 ABCB5 RUVBL2 ABCB1 ABCG4 ABCD3 ASCC3 DNAH5 ATP5F1B	6.57e-06	144	169	9	IPR003593
Domain	-	DNHD1 ABCC3 ABCB5 ARL9 RUVBL2 DDX6 ABCB1 ABCG4 NWD2 TRANK1 FBH1 ABCD3 GNAT3 ASCC3 DNM1 DNAH5 RAB13 ABCG8 RAD54L ATP5F1B	1.42e-05	746	169	20	3.40.50.300
Domain	Plexin_cytopl	PLXNA3 PLXNA4 PLXNA1	5.87e-05	9	169	3	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNA3 PLXNA4 PLXNA1	5.87e-05	9	169	3	IPR013548
Domain	Plexin	PLXNA3 PLXNA4 PLXNA1	5.87e-05	9	169	3	IPR031148
Domain	ELFV_dehydrog_N	GLUD1 GLUD2	8.14e-05	2	169	2	PF02812
Domain	Glu/Leu/Phe/Val_DH_C	GLUD1 GLUD2	8.14e-05	2	169	2	IPR006096
Domain	Glu/Leu/Phe/Val_DH_dimer_dom	GLUD1 GLUD2	8.14e-05	2	169	2	IPR006097
Domain	Glu/Leu/Phe/Val_DH	GLUD1 GLUD2	8.14e-05	2	169	2	IPR006095
Domain	ELFV_dehydrog	GLUD1 GLUD2	8.14e-05	2	169	2	PF00208
Domain	NAD_bind_Glu_DH	GLUD1 GLUD2	8.14e-05	2	169	2	IPR033922
Domain	GLFV_DEHYDROGENASE	GLUD1 GLUD2	8.14e-05	2	169	2	PS00074
Domain	DNA_helicase_UvrD/REP	TRANK1 FBH1	8.14e-05	2	169	2	IPR000212
Domain	ELFV_dehydrog	GLUD1 GLUD2	8.14e-05	2	169	2	SM00839
Domain	Glu/Leu/Phe/Val_DH_AS	GLUD1 GLUD2	8.14e-05	2	169	2	IPR033524
Domain	Cl_channel-K	CLCNKA CLCNKB	8.14e-05	2	169	2	IPR002250
Domain	P-loop_NTPase	DNHD1 ABCC3 ABCB5 ARL9 RUVBL2 DDX6 ABCB1 ABCG4 NWD2 TRANK1 FBH1 ABCD3 GNAT3 ASCC3 DNM1 DNAH5 RAB13 ABCG8 RAD54L ATP5F1B	8.56e-05	848	169	20	IPR027417
Domain	ABC_TM1F	ABCC3 ABCB5 ABCB1 ABCD3	1.12e-04	28	169	4	PS50929
Domain	ABC1_TM_dom	ABCC3 ABCB5 ABCB1 ABCD3	1.12e-04	28	169	4	IPR011527
Domain	Kinase-like_dom	PDGFRA TRPM7 NTRK3 WDR81 ACVR1B ERN2 MAST2 PRDM2 PTK6 TGFBR1 DST KNDC1 MASTL DNM1 RIOK2	1.25e-04	542	169	15	IPR011009
Domain	ABC2_membrane	ABCG4 ABCG8	8.00e-04	5	169	2	PF01061
Domain	ABC_2_trans	ABCG4 ABCG8	8.00e-04	5	169	2	IPR013525
Domain	ABC_membrane	ABCC3 ABCB5 ABCB1	1.28e-03	24	169	3	PF00664
Domain	GS_dom	ACVR1B TGFBR1	1.66e-03	7	169	2	IPR003605
Domain	PInositol-4-P-5-kinase	PIP4K2B PIP4K2C	1.66e-03	7	169	2	IPR023610
Domain	GS	ACVR1B TGFBR1	1.66e-03	7	169	2	PS51256
Domain	Glyco_hydro_22_lys	LYZL4 SPACA5	1.66e-03	7	169	2	IPR000974
Domain	TGF_beta_GS	ACVR1B TGFBR1	1.66e-03	7	169	2	PF08515
Domain	GS	ACVR1B TGFBR1	1.66e-03	7	169	2	SM00467
Domain	HECT	ITCH G2E3 HECTD1	1.81e-03	27	169	3	PF00632
Domain	HECTc	ITCH G2E3 HECTD1	1.81e-03	27	169	3	SM00119
Domain	HECT_dom	ITCH G2E3 HECTD1	1.81e-03	27	169	3	IPR000569
Domain	IPT	PLXNA3 PLXNA4 PLXNA1	1.81e-03	27	169	3	SM00429
Domain	HECT	ITCH G2E3 HECTD1	1.81e-03	27	169	3	PS50237
Domain	PIPKc	PIP4K2B PIP4K2C	2.20e-03	8	169	2	SM00330
Domain	-	PIP4K2B PIP4K2C	2.20e-03	8	169	2	3.30.800.10
Domain	PIP5K	PIP4K2B PIP4K2C	2.20e-03	8	169	2	PF01504
Domain	PIPK	PIP4K2B PIP4K2C	2.20e-03	8	169	2	PS51455
Domain	PInositol-4-P-5-kinase_N	PIP4K2B PIP4K2C	2.20e-03	8	169	2	IPR027484
Domain	PInositol-4-P-5-kinase_C	PIP4K2B PIP4K2C	2.20e-03	8	169	2	IPR027483
Domain	Glyco_hydro_22	LYZL4 SPACA5	2.20e-03	8	169	2	IPR001916
Domain	LACTALBUMIN_LYSOZYME_2	LYZL4 SPACA5	2.20e-03	8	169	2	PS51348
Domain	Lys	LYZL4 SPACA5	2.20e-03	8	169	2	PF00062
Domain	-	PIP4K2B PIP4K2C	2.20e-03	8	169	2	3.30.810.10
Domain	LACTALBUMIN_LYSOZYME_1	LYZL4 SPACA5	2.20e-03	8	169	2	PS00128
Domain	PInositol-4-P-5-kinase_core	PIP4K2B PIP4K2C	2.20e-03	8	169	2	IPR002498
Domain	LYZ1	LYZL4 SPACA5	2.20e-03	8	169	2	SM00263
Domain	Ig_E-set	PLXNA3 PRKAB2 PLXNA4 ASCC3 PLXNA1	2.56e-03	104	169	5	IPR014756
Domain	Semap_dom	PLXNA3 PLXNA4 PLXNA1	2.72e-03	31	169	3	IPR001627
Domain	SEMA	PLXNA3 PLXNA4 PLXNA1	2.72e-03	31	169	3	PS51004
Domain	TIG	PLXNA3 PLXNA4 PLXNA1	2.72e-03	31	169	3	PF01833
Domain	Sema	PLXNA3 PLXNA4 PLXNA1	2.72e-03	31	169	3	SM00630
Domain	Sema	PLXNA3 PLXNA4 PLXNA1	2.72e-03	31	169	3	PF01403
Domain	Cl-channel_core	CLCNKA CLCNKB	2.81e-03	9	169	2	IPR014743
Domain	-	CLCNKA CLCNKB	2.81e-03	9	169	2	1.10.3080.10
Domain	Voltage_CLC	CLCNKA CLCNKB	2.81e-03	9	169	2	PF00654
Domain	BEACH	WDR81 NBEA	2.81e-03	9	169	2	PS50197
Domain	Cl-channel_volt-gated	CLCNKA CLCNKB	2.81e-03	9	169	2	IPR001807
Domain	Beach	WDR81 NBEA	2.81e-03	9	169	2	PF02138
Domain	-	WDR81 NBEA	2.81e-03	9	169	2	1.10.1540.10
Domain	Beach	WDR81 NBEA	2.81e-03	9	169	2	SM01026
Domain	BEACH_dom	WDR81 NBEA	2.81e-03	9	169	2	IPR000409
Domain	IPT	PLXNA3 PLXNA4 PLXNA1	2.98e-03	32	169	3	IPR002909
Domain	Plexin_repeat	PLXNA3 PLXNA4 PLXNA1	2.98e-03	32	169	3	IPR002165
Domain	PSI	PLXNA3 PLXNA4 PLXNA1	2.98e-03	32	169	3	PF01437
Pathway	KEGG_ABC_TRANSPORTERS	ABCC3 ABCB5 ABCB1 ABCG4 ABCD3 ABCG8	2.10e-06	44	123	6	M11911
Pathway	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	PLXNA3 PLXNA4 PLXNA1	5.24e-05	9	123	3	MM15030
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	ABCC3 ATP7A TRPM7 ESYT1 ABCB5 ATP10B SLC39A10 ADCY3 ANO8 ABCB1 ABCG4 SLC7A1 CLCNKA CLCNKB LCN15 ABCD3 NCEH1 ABCG8	6.78e-05	736	123	18	M27287
Pathway	REACTOME_POSTMITOTIC_NUCLEAR_PORE_COMPLEX_NPC_REFORMATION	TNPO1 AHCTF1 NUP205 NUP155	8.29e-05	27	123	4	M29807
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	ABCC3 ABCB1 ABCD3 NR1H4	1.27e-04	30	123	4	MM15866
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	ABCC3 ABCB1 ABCD3 NR1H4	1.86e-04	33	123	4	MM1448
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	ABCC3 ABCB1 ABCD3 NR1H4	2.09e-04	34	123	4	M16393
Pathway	REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION	PLXNA3 PLXNA4 PLXNA1	2.20e-04	14	123	3	MM15029
Pathway	REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION	PLXNA3 PLXNA4 PLXNA1	2.20e-04	14	123	3	M7578
Pathway	REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT	ABCC3 ABCB5 ABCB1 ABCG4 ABCD3 ABCG8	2.26e-04	99	123	6	MM14986
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	ABCC3 ABCB1 ABCD3 NR1H4	2.34e-04	35	123	4	M39488
Pathway	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	PLXNA3 PLXNA4 PLXNA1	2.73e-04	15	123	3	MM15031
Pathway	REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT	ABCC3 ABCB5 ABCB1 ABCG4 ABCD3 ABCG8	2.80e-04	103	123	6	M758
Pathway	REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION	PLXNA3 PLXNA4 PLXNA1	3.34e-04	16	123	3	M16498
Pathway	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	PLXNA3 PLXNA4 PLXNA1	3.34e-04	16	123	3	M8245
Pathway	WP_DRUG_INDUCTION_OF_BILE_ACID_PATHWAY	ABCC3 ABCB1 NR1H4	4.03e-04	17	123	3	M39666
Pathway	REACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS	ABCG4 ABCD3 ABCG8	4.03e-04	17	123	3	MM14552
Pathway	REACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS	ABCG4 ABCD3 ABCG8	4.81e-04	18	123	3	M524
Pathway	REACTOME_NUCLEAR_ENVELOPE_NE_REASSEMBLY	TNPO1 AHCTF1 NUP205 NUP155 CCNB2	5.25e-04	76	123	5	M27215
Pathway	WP_CHOLESTASIS	ABCC3 ABCG8 NR1H4	5.67e-04	19	123	3	M45520
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	TNPO1 DNHD1 NRDC ESYT1 LRRC40 CMYA5 MAST2 AHSA1 RUVBL2 PRDM2 DDX6 NUP205 RBM25 NUP155 SQSTM1 EIF2B1 GLUD1 ABCD3 SCPEP1 HADHA TDRD6 RPA1 DNAH5 NIPBL PLXNA1 ATP5F1B	6.59e-09	1425	169	26	30948266
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	ITCH AIMP2 ESYT1 AHCTF1 LRRC40 RUVBL2 NKRF DDX6 NUP205 ACSL1 DST NUP155 MICAL2 SQSTM1 ABCD3 EXOC1 HADHA PIP4K2C ASCC3 RPA1 MGA RIOK2 NIPBL RAB13 ATP5F1B	1.04e-08	1353	169	25	29467282
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	TNPO1 AIMP2 COPZ1 ESYT1 LRRC40 AHSA1 RUVBL2 NKRF DDX6 NUP205 NUP155 ABCD3 HADHA ASCC3 RPA1 HECTD1 ATP5F1B	1.69e-08	638	169	17	33239621
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	DOCK11 TNPO2 LAMA1 LRRC40 NBEA ACVR1B QRICH2 PRDM2 NUP205 FANCA TMCO4 FRY DST ABCD3 PLXNA4 GNAT3 HADHA RPA1	2.33e-08	736	169	18	29676528
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	ITCH ATP7A TRPM7 PPFIBP1 ESYT1 GPAT3 WDR81 NBEA SLC39A10 HPS3 DST NUP155 USP32 ABCD3 PLXNA1	2.92e-08	504	169	15	34432599
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	TNPO1 KRT5 KRT84 LRRC40 RUVBL2 NKRF DDX6 ABCB1 NUP205 RBM25 DST NUP155 SQSTM1 GLUD1 ABCD3 HADHA ASCC3 RPA1 MGA NIPBL ATP5F1B	3.06e-08	1024	169	21	24711643
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	TNPO1 ATP7A PPFIBP1 ESYT1 AHCTF1 LRRC40 RUVBL2 DDX6 RBM25 DST NUP155 ABCD3 HADHA ASCC3 RPA1 USP6NL ATP5F1B	7.58e-08	708	169	17	39231216
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	TNPO1 SYNRG COPZ1 AHSA1 RUVBL2 DDX6 NUP205 RBM25 DST GLUD1 ABCD3 MGA RIOK2 HECTD1 ATP5F1B	8.46e-08	547	169	15	37267103
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	CUL4A AIMP2 ESYT1 AHCTF1 LRRC40 AHSA1 RUVBL2 NKRF DDX6 NUP205 LIG1 RBM25 GLUD1 ABCD3 PIP4K2B HADHA PIP4K2C ASCC3 RPA1 RIOK2 NIPBL RAB13 ATP5F1B	1.20e-07	1318	169	23	30463901
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	TNPO1 CUL4A ITCH AIMP2 COPZ1 AHSA1 RUVBL2 NKRF DDX6 RBM25 PPT1 MICAL2 SQSTM1 GLUD1 ABCD3 HADHA ASCC3 RPA1 MGA HECTD1 RAB13 ATP5F1B	1.92e-07	1247	169	22	27684187
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	TNPO1 KRT5 ITCH AIMP2 PPFIBP1 ESYT1 KRT84 AHCTF1 AHSA1 RUVBL2 NKRF DDX6 NUP205 RBM25 DST NUP155 SQSTM1 GLUD1 ABCD3 HADHA ASCC3 ATP5F1B	2.20e-07	1257	169	22	36526897
Pubmed	Defining the membrane proteome of NK cells.	KRT5 ITCH ATP7A AIMP2 ELMOD2 PDGFRA ESYT1 CCDC126 LRRC40 ADCY3 DDX6 NUP205 ACSL1 SLC7A1 NUP155 PPT1 ABCD3 NCEH1 EXOC1 ASCC3 ATP5F1B	2.74e-07	1168	169	21	19946888
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	KRT5 ATP7A COPZ1 TRPM7 PPFIBP1 ESYT1 NBEA ACVR1B SLC39A10 ARID3B PCF11 LIG1 DST NUP155 SQSTM1 ABCD3 MGA	2.81e-07	777	169	17	35844135
Pubmed	Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation.	PLXNA3 ITGA9 PLXNA4 PLXNA1	3.72e-07	13	169	4	22723296
Pubmed	Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.	PLXNA3 PLXNA4 PLXNA1	4.49e-07	4	169	3	11306810
Pubmed	PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.	PLXNA3 PLXNA4 PLXNA1	4.49e-07	4	169	3	25518740
Pubmed	Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.	CUL4A AIMP2 AHSA1 RUVBL2 SQSTM1 GLUD1 GLUD2 HADHA DNM1 ATP5F1B	5.61e-07	256	169	10	35777956
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	ISCA1 COPZ1 PDGFRA ADAMTS1 ESYT1 CNTNAP1 ADAMTS5 SLC39A10 ACSL1 LIG1 RBM25 NUP155 GLUD1 GLUD2 ABCD3 PIP4K2B SCPEP1 NCEH1 HADHA PIP4K2C USP6NL PLXNA1 ATP5F1B	6.40e-07	1451	169	23	30550785
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	TNPO1 CUL4A NRDC TNPO2 ESYT1 LRRC40 AHSA1 ARID3B ACSL1 NUP155 SQSTM1 ABCD3 EXOC1 HADHA	7.00e-07	560	169	14	35241646
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	ABCC3 ITCH LZTR1 TRPM7 PPFIBP1 SLC39A10 ABCB1 SLC7A1 MICAL2 USP32 PLSCR3 USP6NL RAB13 PLXNA1	8.45e-07	569	169	14	30639242
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	ATP7A COPZ1 ELMOD2 PPFIBP1 ESYT1 GPAT3 SLC39A10 NUP205 SLC7A1 BNIP3 NUP155 GLUD1 GLUD2 USP32 HADHA RAB13 PLXNA1 ATP5F1B	1.02e-06	952	169	18	38569033
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CUL4A SYNRG ITCH PDGFRA TRPM7 DOCK11 PPFIBP1 ESYT1 NTRK3 MAST2 DDX6 C2CD3 DST SQSTM1 HECTD1 RGL2 USP6NL	1.15e-06	861	169	17	36931259
Pubmed	Genetic susceptibility to distinct bladder cancer subphenotypes.	AIMP2 OCA2 FAS TTC6 ABCB1 FANCA TGFBR1 LIG1 HADHA ABCG8 NR1H4 RAD54L	1.17e-06	421	169	12	19692168
Pubmed	Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.	TNPO1 DST CCNB2 SQSTM1 GLUD1 PRKAB2 MASTL PIP4K2B HADHA PIP4K2C RIOK2 HECTD1	1.52e-06	432	169	12	23455922
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PLXNA3 CACNA1C KRT5 PCDHGA11 COL20A1 KRT84 ABCB5 ATP10B ABCB1 NUP205 PCF11 C2CD3 DST GLUD1 GLUD2 PLXNA4 PIP4K2B MYOM2 HADHA POTEJ NIPBL ATP5F1B	2.14e-06	1442	169	22	35575683
Pubmed	Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.	AIMP2 OCA2 FAS ABCB1 FANCA TGFBR1 LIG1 HADHA ABCG8 NR1H4 RAD54L	2.99e-06	382	169	11	19170196
Pubmed	Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.	LZTR1 PPFIBP1 ESYT1 SLC39A10 SLC7A1 NUP155 CCNB2 ABCD3 PLSCR3 USP6NL RAB13 PLXNA1	3.39e-06	467	169	12	30194290
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	AIMP2 ESYT1 FAS AHSA1 RUVBL2 NKRF DDX6 NUP205 ACSL1 NUP155 PPT1 SQSTM1 GLUD1 GLUD2 ABCD3 HADHA ASCC3 RPA1 HECTD1 ATP5F1B	3.47e-06	1257	169	20	37317656
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	TNPO1 ITCH ADAMTS1 ESYT1 AHCTF1 LRRC40 FAS NUP205 FANCA SLC7A1 NUP155 CCNB2 SQSTM1 ABCD3 HADHA ASCC3 HECTD1	3.84e-06	942	169	17	31073040
Pubmed	Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.	PLXNA3 PLXNA4 PLXNA1	3.89e-06	7	169	3	19063725
Pubmed	Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.	PLXNA3 PLXNA4 PLXNA1	3.89e-06	7	169	3	19655386
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ITCH ADAMTS1 TRPM7 PPFIBP1 TNPO2 CNTNAP1 NBEA CMYA5 FRY DST FBH1 PPT1 MICAL2 GLUD1 USP32 EXOC1 DNM1 HECTD1 NIPBL ATP5F1B	4.81e-06	1285	169	20	35914814
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TNPO1 P4HA2 NRDC KRT84 AHCTF1 G2E3 SLC39A10 ITGA9 SPPL2B ADCY3 PRDM2 TGFBR1 SLC7A1 CLCNKA SQSTM1 MASTL RPA1 MGA	6.19e-06	1084	169	18	11544199
Pubmed	The expression of plexins during mouse embryogenesis.	PLXNA3 PLXNA4 PLXNA1	6.20e-06	8	169	3	15661641
Pubmed	POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer.	POTEB2 POTEJ POTEB	6.20e-06	8	169	3	12475935
Pubmed	Integration of opposing semaphorin guidance cues in cortical axons.	PLXNA3 PLXNA4 PLXNA1	6.20e-06	8	169	3	22368082
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	PLXNA3 ABCC3 P4HA2 ESYT1 CNTNAP1 LAMA1 SLC39A10 FANCA TGFBR1 PPT1 MICAL2 SQSTM1 SCAPER SCPEP1 NCEH1 HECTD1 TMEM258 PLXNA1 ATP5F1B	6.71e-06	1201	169	19	35696571
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	TNPO1 P4HA2 COPZ1 ELMOD2 ESYT1 AHCTF1 CNTNAP1 GPAT3 SLC39A10 NUP205 SLC7A1 NUP155 MICAL2 SQSTM1 ABCD3 NCEH1 MGA USP6NL ATP5F1B	6.87e-06	1203	169	19	29180619
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	DNHD1 LAMA1 PRDM2 ABCD3 DNM1 RPA1 DNAH5 ATP5F1B	8.76e-06	208	169	8	33230847
Pubmed	The role of neuropilins in cell signalling.	PLXNA3 PLXNA4 PLXNA1	9.27e-06	9	169	3	19909241
Pubmed	Evolutionarily conserved regulators of tau identify targets for new therapies.	ITCH ATP7A ESYT1 SLC39A10 RUVBL2 TGFBR1 SLC7A1 NUP155 HADHA TMEM258 PLXNA1 ATP5F1B	9.28e-06	516	169	12	36610398
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ESYT1 ATP10B MAST2 DST NUP155 MICAL2	1.04e-05	101	169	6	9872452
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	DOCK11 ESYT1 NKRF DDX6 NUP205 PCF11 NUP155 BRD7 ABCD3 ASCC3 HECTD1	1.13e-05	440	169	11	34244565
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	SYNRG ATP7A AHCTF1 NBEA BNIP2 DST SQSTM1 USP32 USP6NL	1.17e-05	285	169	9	34369648
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	KRT5 ISCA1 TRPM7 ESYT1 AHCTF1 GPAT3 LRRC40 SLC25A51 NKRF BNIP3 DST NUP155 SQSTM1 GLUD1 BRD7 ABCD3 HADHA TRMT61B RPA1 RAB13 ATP5F1B	1.32e-05	1496	169	21	32877691
Pubmed	Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.	PLXNA3 PLXNA4 PLXNA1	1.32e-05	10	169	3	18804103
Pubmed	Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction.	KRT5 COL20A1 LAMA1 MYOM2	1.53e-05	31	169	4	22282597
Pubmed	PTEN identified as important risk factor of chronic obstructive pulmonary disease.	AIMP2 OCA2 FAS ABCB1 FANCA TGFBR1 LIG1 HADHA NR1H4 RAD54L	1.61e-05	374	169	10	19625176
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	ATP7A TRPM7 PPFIBP1 ESYT1 SLC39A10 ADCY3 DST PLSCR3 USP6NL RAB13	1.73e-05	377	169	10	38117590
Pubmed	Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs.	ACVR1B TGFBR1 BMP2	1.81e-05	11	169	3	7791754
Pubmed	Control of pelage hair follicle development and cycling by complex interactions between follistatin and activin.	KRT5 ACVR1B BMP2	1.81e-05	11	169	3	12514121
Pubmed	Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.	AIMP2 OCA2 ABCB1 FANCA TGFBR1 LIG1 HADHA ABCG8 NR1H4 RAD54L	1.89e-05	381	169	10	18676680
Pubmed	Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodies.	RUVBL2 SQSTM1 GLUD1 ABCD3 HADHA	1.93e-05	67	169	5	30669930
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	ESYT1 AHCTF1 NUP205 NUP155 ABCD3 HADHA ASCC3 RAB13	2.25e-05	237	169	8	29564676
Pubmed	Quantitative Assessment of the Association between ABC Polymorphisms and Osteosarcoma Response: a Meta-analysis.	ABCC3 ABCB1	2.35e-05	2	169	2	26107220
Pubmed	Glutamate Delta-1 Receptor Regulates Inhibitory Neurotransmission in the Nucleus Accumbens Core and Anxiety-Like Behaviors.	GLUD1 GLUD2	2.35e-05	2	169	2	34173171
Pubmed	Glutamate dehydrogenase is essential to sustain neuronal oxidative energy metabolism during stimulation.	GLUD1 GLUD2	2.35e-05	2	169	2	28621566
Pubmed	The ClC-K2 Chloride Channel Is Critical for Salt Handling in the Distal Nephron.	CLCNKA CLCNKB	2.35e-05	2	169	2	27335120
Pubmed	Effect of ABCB1 and ABCC3 polymorphisms on osteosarcoma survival after chemotherapy: a pharmacogenetic study.	ABCC3 ABCB1	2.35e-05	2	169	2	22016816
Pubmed	GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior.	GLUD1 GLUD2	2.35e-05	2	169	2	32078638
Pubmed	Assignment of the genes encoding the human chloride channels, CLCNKA and CLCNKB, to 1p36 and of CLCN3 to 4q32-q33 by in situ hybridization.	CLCNKA CLCNKB	2.35e-05	2	169	2	8812470
Pubmed	USP32 is an active, membrane-bound ubiquitin protease overexpressed in breast cancers.	USP6 USP32	2.35e-05	2	169	2	20549504
Pubmed	Development of mice with brain-specific deletion of floxed glud1 (glutamate dehydrogenase 1) using cre recombinase driven by the nestin promoter.	GLUD1 GLUD2	2.35e-05	2	169	2	23595828
Pubmed	Associations between CLCNKA_B tag SNPs with essential hypertension and interactions between genetic and environmental factors in an island population in China.	CLCNKA CLCNKB	2.35e-05	2	169	2	25919862
Pubmed	Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways.	GLUD1 GLUD2	2.35e-05	2	169	2	21621574
Pubmed	Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia.	GLUD1 GLUD2	2.35e-05	2	169	2	28911206
Pubmed	Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase.	GLUD1 GLUD2	2.35e-05	2	169	2	22875990
Pubmed	Blockade of ALK4/5 signaling suppresses cadmium- and erastin-induced cell death in renal proximal tubular epithelial cells via distinct signaling mechanisms.	ACVR1B TGFBR1	2.35e-05	2	169	2	30804470
Pubmed	Molecular basis of human glutamate dehydrogenase regulation under changing energy demands.	GLUD1 GLUD2	2.35e-05	2	169	2	15578726
Pubmed	P-glycoprotein is not involved in pathway of anti-Fas/Fas-induced apoptosis in KBv200 cells.	FAS ABCB1	2.35e-05	2	169	2	15962371
Pubmed	Important role of Ser443 in different thermal stability of human glutamate dehydrogenase isozymes.	GLUD1 GLUD2	2.35e-05	2	169	2	15044002
Pubmed	Induction of excitatory and inhibitory presynaptic differentiation by GluD1.	GLUD1 GLUD2	2.35e-05	2	169	2	22138648
Pubmed	Expanding Genotype-Phenotype Correlation of CLCNKA and CLCNKB Variants Linked to Hearing Loss.	CLCNKA CLCNKB	2.35e-05	2	169	2	38069401
Pubmed	Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia.	GLUD1 GLUD2	2.35e-05	2	169	2	34220417
Pubmed	Expression of human GLUD1 and GLUD2 glutamate dehydrogenases in steroid producing tissues.	GLUD1 GLUD2	2.35e-05	2	169	2	26241911
Pubmed	Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum.	GLUD1 GLUD2	2.35e-05	2	169	2	21446915
Pubmed	Intestinal Farnesoid X Receptor Controls Transintestinal Cholesterol Excretion in Mice.	ABCG8 NR1H4	2.35e-05	2	169	2	28065787
Pubmed	A regulatory calcium-binding site at the subunit interface of CLC-K kidney chloride channels.	CLCNKA CLCNKB	2.35e-05	2	169	2	20805576
Pubmed	Cleavage of TRPM7 releases the kinase domain from the ion channel and regulates its participation in Fas-induced apoptosis.	TRPM7 FAS	2.35e-05	2	169	2	22698280
Pubmed	GluD1 binds GABA and controls inhibitory plasticity.	GLUD1 GLUD2	2.35e-05	2	169	2	38060673
Pubmed	Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type mice.	GLUD1 GLUD2	2.35e-05	2	169	2	24593767
Pubmed	Potentiation of neuronal activity by tonic GluD1 current in brain slices.	GLUD1 GLUD2	2.35e-05	2	169	2	37154294
Pubmed	Tissue specific induction of p62/Sqstm1 by farnesoid X receptor.	SQSTM1 NR1H4	2.35e-05	2	169	2	22952826
Pubmed	Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission.	GLUD1 GLUD2	2.35e-05	2	169	2	22924626
Pubmed	Lack of Tgfbr1 and Acvr1b synergistically stimulates myofibre hypertrophy and accelerates muscle regeneration.	ACVR1B TGFBR1	2.35e-05	2	169	2	35323108
Pubmed	SLC25A51 is a mammalian mitochondrial NAD+ transporter.	SLC25A51 SLC25A52	2.35e-05	2	169	2	32906142
Pubmed	Nerve tissue-specific (GLUD2) and housekeeping (GLUD1) human glutamate dehydrogenases are regulated by distinct allosteric mechanisms: implications for biologic function.	GLUD1 GLUD2	2.35e-05	2	169	2	11032875
Pubmed	Salt wasting and deafness resulting from mutations in two chloride channels.	CLCNKA CLCNKB	2.35e-05	2	169	2	15044642
Pubmed	Localization of Human Glutamate Dehydrogenases Provides Insights into Their Metabolic Role and Their Involvement in Disease Processes.	GLUD1 GLUD2	2.35e-05	2	169	2	29943084
Pubmed	Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins.	TNPO1 TNPO2	2.35e-05	2	169	2	9298975
Pubmed	Two highly homologous members of the ClC chloride channel family in both rat and human kidney.	CLCNKA CLCNKB	2.35e-05	2	169	2	8041726
Pubmed	Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory.	GLUD1 GLUD2	2.35e-05	2	169	2	31898404
Pubmed	Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux.	GLUD1 GLUD2	2.35e-05	2	169	2	15378063
Pubmed	A cytoplasmic domain mutation in ClC-Kb affects long-distance communication across the membrane.	CLCNKA CLCNKB	2.35e-05	2	169	2	18648499
Pubmed	Widening Spectrum of Cellular and Subcellular Expression of Human GLUD1 and GLUD2 Glutamate Dehydrogenases Suggests Novel Functions.	GLUD1 GLUD2	2.35e-05	2	169	2	27422263
Pubmed	Using genomewide mutagenesis screens to identify the genes required for neural tube closure in the mouse.	TBC1D32 C2CD3	2.35e-05	2	169	2	15971254
Pubmed	Cloning, tissue distribution, and intrarenal localization of ClC chloride channels in human kidney.	CLCNKA CLCNKB	2.35e-05	2	169	2	8544406
Pubmed	Critical role of the cysteine 323 residue in the catalytic activity of human glutamate dehydrogenase isozymes.	GLUD1 GLUD2	2.35e-05	2	169	2	15750346
Pubmed	Molecular cloning, structure and expression analysis of a full-length mouse brain glutamate dehydrogenase cDNA.	GLUD1 GLUD2	2.35e-05	2	169	2	1711373
Pubmed	Modulation of MDR1 and MRP3 gene expression in lung cancer cells after paclitaxel and carboplatin exposure.	ABCC3 ABCB1	2.35e-05	2	169	2	23443122
Interaction	KCNA3 interactions	TNPO1 DNHD1 ATP7A PPFIBP1 ESYT1 AHCTF1 LAMA1 LRRC40 RUVBL2 PRDM2 DDX6 PTP4A3 RBM25 DST NUP155 ABCD3 HADHA ASCC3 DNM1 RPA1 DNAH5 USP6NL ATP5F1B	7.99e-07	871	166	23	int:KCNA3
Interaction	HRAS interactions	CUL4A ABCC3 LZTR1 ATP7A TRPM7 PPFIBP1 NTRK3 GPAT3 SLC39A10 SLC7A1 MICAL2 USP32 KNDC1 EXOC1 PLSCR3 HECTD1 RGL2 USP6NL RAB13 PLXNA1	2.31e-06	725	166	20	int:HRAS
Interaction	RHOB interactions	ITCH ATP7A TRPM7 DOCK11 PPFIBP1 ESYT1 NBEA ACVR1B SLC39A10 ADCY3 NUP205 TGFBR1 SLC7A1 NUP155 USP32 HADHA PLSCR3 PIP4K2C USP6NL RAB13 PLXNA1	5.88e-06	840	166	21	int:RHOB
Interaction	RNF149 interactions	ITCH ATP7A ESYT1 ACVR1B SLC39A10 RUVBL2 TGFBR1 SLC7A1 RBM25 BNIP3 NUP155 PLXNA4 HADHA TMEM258 PLXNA1 ATP5F1B	1.29e-05	549	166	16	int:RNF149
Interaction	SEMA5A interactions	PLXNA3 PLXNA4 PLXNA1	1.87e-05	7	166	3	int:SEMA5A
Interaction	RAB35 interactions	ATP7A TRPM7 PPFIBP1 ESYT1 GPAT3 SLC39A10 FAS ADCY3 SLC7A1 DST USP32 ABCD3 RPA1 USP6NL RAB13 PLXNA1	2.18e-05	573	166	16	int:RAB35
Interaction	LAMP1 interactions	CUL4A ATP7A TRPM7 PPFIBP1 ESYT1 NTRK3 GPAT3 NBEA SLC39A10 SPPL2B NUP205 TGFBR1 DST USP32 RPA1 USP6NL RAB13	2.44e-05	644	166	17	int:LAMP1
Interaction	CA14 interactions	TNPO1 TNPO2 SLC7A1 EIF2B1 EXOC1 RAB13	2.62e-05	71	166	6	int:CA14
Interaction	MAP1B interactions	TNPO1 CUL4A AIMP2 TNPO2 AHSA1 RUVBL2 PPT1 SQSTM1 GLUD1 GLUD2 HADHA DNM1 RPA1 HECTD1 ATP5F1B	4.13e-05	539	166	15	int:MAP1B
Interaction	RAB7A interactions	ITCH ATP7A TRPM7 PPFIBP1 ESYT1 GPAT3 WDR81 NBEA SLC39A10 HPS3 DST NUP155 SQSTM1 USP32 ABCD3 HADHA RPA1 RAB13 PLXNA1 ATP5F1B	4.29e-05	886	166	20	int:RAB7A
Interaction	KPNB1 interactions	TNPO1 CUL4A ITCH AIMP2 TNPO2 FAS AHSA1 RUVBL2 NUP205 NUP155 PPT1 SQSTM1 BRD7 HADHA RPA1	4.59e-05	544	166	15	int:KPNB1
Interaction	RNF123 interactions	DOCK11 TNPO2 LAMA1 LRRC40 NBEA ACVR1B FAS QRICH2 PRDM2 NUP205 FANCA TMCO4 FRY DST ABCD3 PLXNA4 GNAT3 HADHA RPA1	5.08e-05	824	166	19	int:RNF123
Interaction	ACSL3 interactions	DOCK11 ESYT1 NTRK3 FAS TIGD6 TBC1D32 NUP155 SQSTM1 BRD7 RPA1	5.74e-05	258	166	10	int:ACSL3
Interaction	DIRAS3 interactions	ATP7A TRPM7 PPFIBP1 NBEA SLC39A10 SLC7A1 DST HECTD1 USP6NL ATP5F1B	6.53e-05	262	166	10	int:DIRAS3
Interaction	NRAS interactions	ITCH LZTR1 ATP7A TRPM7 PPFIBP1 ESYT1 SLC39A10 SLC7A1 USP32 ABCD3 EXOC1 PLSCR3 RPA1 RGL2 USP6NL RAB13 PLXNA1	6.77e-05	699	166	17	int:NRAS
GeneFamily	Plexins	PLXNA3 PLXNA4 PLXNA1	2.51e-05	9	123	3	683
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEB2 POTEJ POTEB	8.36e-05	13	123	3	685
GeneFamily	DNA helicases	RUVBL2 FBH1 ASCC3	1.95e-04	17	123	3	1167
GeneFamily	Blood group antigens\|CD molecules\|ATP binding cassette subfamily G	ABCG4 ABCG8	4.53e-04	5	123	2	811
GeneFamily	Type 1 receptor serine/threonine kinases	ACVR1B TGFBR1	9.43e-04	7	123	2	345
GeneFamily	Nucleoporins	AHCTF1 NUP205 NUP155	1.32e-03	32	123	3	1051
GeneFamily	WD repeat domain containing\|BEACH domain containing	WDR81 NBEA	1.60e-03	9	123	2	1230
GeneFamily	Lysozymes, c-type	LYZL4 SPACA5	1.60e-03	9	123	2	1174
GeneFamily	Chloride voltage-gated channels	CLCNKA CLCNKB	1.99e-03	10	123	2	302
GeneFamily	ATP binding cassette subfamily B	ABCB5 ABCB1	2.43e-03	11	123	2	806
Coexpression	GSE17721_0.5H_VS_24H_PAM3CSK4_BMDC_DN	ABCC3 TNPO2 LRRC40 AHSA1 HPS3 ABCB1 GUCA1A HADHA HECTD1	6.09e-06	200	168	9	M4114
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_B\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	COPZ1 G2E3 CCNQ METTL21A ABCD3 SCPEP1 MYOM2 TMEM258	8.67e-07	195	170	8	6d6c1197d6fd56f628ec9d22723abcb9700306f7
ToppCell	COVID-19-kidney-vSMC/Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1C ADAMTS1 NTRK3 ADCY3 FRY PTP4A3 MYOM2	5.84e-06	179	170	7	111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	CACNA1C TRPM7 PPFIBP1 CMYA5 FRY NCEH1 MYOM2	7.25e-06	185	170	7	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	TRPM7 CMYA5 MAST2 FRY NCEH1 MYOM2 HADHA	8.33e-06	189	170	7	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS1 NTRK3 ADCY3 FRY PTP4A3 MICAL2 MYOM2	9.23e-06	192	170	7	bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS1 NTRK3 ADCY3 FRY PTP4A3 MICAL2 MYOM2	9.23e-06	192	170	7	b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell	droplet-Liver-nan-3m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MIER3 ITGA9 HPS3 FRY BNIP2 FBH1	9.44e-06	127	170	6	39fa20a55de3af1a62ab5dfa4877879db3935ac2
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PPFIBP1 SLC39A10 ABCB1 SLC52A3 SLC7A1 FRY RAB13	1.13e-05	198	170	7	0a4626b51ba8b52acbaf616f0ced850079cd7149
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PDGFRA ADAMTS1 ADAMTS5 CMYA5 ITGA9 DST PLXNA4	1.17e-05	199	170	7	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	P4HA2 TNPO2 TIGD6 ACSL1 SLC7A1 MASTL	2.34e-05	149	170	6	c773c2b9685ec44a35246180a93456c8765353f5
ToppCell	368C-Lymphocytic-NK_cells\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	P4HA2 ABCB1 BMP2 MYOM2 TNNC1 RAD54L	2.43e-05	150	170	6	17b3ac5ddc47b9cba0a27b268d63a6e491b2b111
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PDGFRA COL20A1 CMYA5 FAS ABCB1 SLC7A1	2.62e-05	152	170	6	6aad62b5b5ad2f78c6600f37960338d40628a439
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK3 ADCY3 FRY PTP4A3 MICAL2 MYOM2	4.90e-05	170	170	6	99dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK3 ADCY3 FRY PTP4A3 MICAL2 MYOM2	4.90e-05	170	170	6	3a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK3 ADCY3 FRY PTP4A3 MICAL2 MYOM2	4.90e-05	170	170	6	cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDGFRA G2E3 ADAMTS5 ITGA9 ADCY3 CCNB2	5.57e-05	174	170	6	7fb7bdf62563f2102fb38618b503eb2817b6594f
ToppCell	COVID-19-Heart-VSMC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1C ADAMTS1 NTRK3 ADCY3 FRY PTP4A3	5.75e-05	175	170	6	1125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPAT3 SPPL2B SLC52A3 TMCO4 SLC16A4 RAD54L	5.94e-05	176	170	6	3766e0533b103ec92ac75eba3df02e287efc53fa
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPAT3 SPPL2B SLC52A3 TMCO4 SLC16A4 RAD54L	5.94e-05	176	170	6	aa1bada2175d8370fc71939a607407155259d195
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NRDC ADAMTS1 GRIK4 TRANK1 MYOM2 ATP5F1B	6.13e-05	177	170	6	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NRDC ADAMTS1 GRIK4 TRANK1 MYOM2 ATP5F1B	6.13e-05	177	170	6	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDGFRA ADAMTS1 PPFIBP1 NBEA NWD2 RTL3	6.13e-05	177	170	6	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	NRDC ADAMTS1 GRIK4 TRANK1 MYOM2 ATP5F1B	6.13e-05	177	170	6	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	NRDC ADAMTS1 GRIK4 TRANK1 MYOM2 ATP5F1B	6.13e-05	177	170	6	936ab2b180a052387124f68d0c7f41c0b164e748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NRDC ADAMTS1 GRIK4 TRANK1 MYOM2 ATP5F1B	6.13e-05	177	170	6	d5aeda113afaa2425874394610344570c9078478
ToppCell	COVID-19-kidney-REN+Pericyte\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1C PDGFRA NTRK3 CNTNAP1 ADCY3 MICAL2	6.52e-05	179	170	6	342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCell	LV\|World / Chamber and Cluster_Paper	TRPM7 PPFIBP1 ITGA9 ABCB1 NCEH1 MYOM2	6.72e-05	180	170	6	5ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NBEA ITGA9 ERN2 TTC6 PLXNA4 DNAH5	6.72e-05	180	170	6	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	RV\|World / Chamber and Cluster_Paper	TRPM7 PPFIBP1 CMYA5 ITGA9 NCEH1 MYOM2	6.93e-05	181	170	6	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	CACNA1C ADAMTS1 NTRK3 FRY DST PLXNA4	8.30e-05	187	170	6	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	facs-Kidney-nan-3m-Epithelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT5 ACSL1 DST CLCNKA CLCNKB ATP5F1B	8.30e-05	187	170	6	208686e6ebc9f3a774bcbe89274457ac9449f90e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GIPC2 DOCK11 PPFIBP1 ABCB1 DNM1 NR1H4	8.30e-05	187	170	6	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C PDGFRA ADAMTS1 ADAMTS5 ITGA9 PLXNA4	8.30e-05	187	170	6	c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	TRPM7 PPFIBP1 CMYA5 NCEH1 MYOM2 HADHA	8.30e-05	187	170	6	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK3 ADCY3 FRY PTP4A3 MICAL2 MYOM2	8.80e-05	189	170	6	7fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCell	Mesenchymal-myofibroblast_cell\|World / Lineage, Cell type, age group and donor	CACNA1C PDGFRA ADAMTS1 ADAMTS5 ITGA9 PLXNA4	8.80e-05	189	170	6	44e37f88137bb249933eb615235b2cf2ae7f3925
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	CACNA1C TRPM7 PPFIBP1 CMYA5 NCEH1 MYOM2	8.80e-05	189	170	6	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NTRK3 ADCY3 FRY PTP4A3 MICAL2 MYOM2	8.80e-05	189	170	6	06b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 GIPC2 DOCK11 PPFIBP1 ABCB1 DNM1	8.80e-05	189	170	6	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	NBEA ITGA9 ERN2 TTC6 PLXNA4 DNAH5	9.06e-05	190	170	6	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	CACNA1C TRPM7 PPFIBP1 CMYA5 NCEH1 MYOM2	9.06e-05	190	170	6	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	CACNA1C TRPM7 PPFIBP1 CMYA5 DST MYOM2	9.06e-05	190	170	6	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	COVID-19-kidney-vSMC/Pericyte\|kidney / Disease (COVID-19 only), tissue and cell type	CACNA1C NTRK3 ADCY3 FRY PTP4A3 MYOM2	9.32e-05	191	170	6	fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C COL6A5 ADAMTS5 ITGA9 NWD2 PLXNA4	9.32e-05	191	170	6	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	HPS3 ARID3B TGFBR1 SLC7A1 NUP155 CCNB2	9.32e-05	191	170	6	39ef8e1d7cc3ebb11717e8a55501515e3b72b177
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	TRPM7 CMYA5 MAST2 FRY NCEH1 MYOM2	9.59e-05	192	170	6	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDGFRA GPAT3 ARL9 CMYA5 ITGA9 RTL3	9.87e-05	193	170	6	7cd9671e0ac64f7f3607f564485c63abbb7e7a63
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIBP1 SLC39A10 FAS SLC52A3 SLC7A1 SLC16A4	9.87e-05	193	170	6	e4b440d50ae7391b26924778be6d9d53e0692449
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIBP1 SLC39A10 FAS SLC52A3 SLC7A1 SLC16A4	9.87e-05	193	170	6	e523dc5751f6fdcd4fc1a62b1eecd43f6ae79da9
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	TNPO1 SYNRG G2E3 USP32 MGA HECTD1	9.87e-05	193	170	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIBP1 SLC39A10 FAS SLC52A3 SLC7A1 SLC16A4	9.87e-05	193	170	6	1772f2ac217727de63c4a9303881b3a19a6bb0f0
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	CACNA1C PDGFRA ADAMTS1 COL6A5 GRIK4 DST	1.04e-04	195	170	6	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	Monocytes-NUPR1+_Monocytes\|Monocytes / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	ABCC3 ESYT1 TGFBR1 NCEH1 DNM1 ATP5F1B	1.10e-04	197	170	6	8a058c9d9285acd7cf2fb8e34f7602a86b5d6c89
ToppCell	Bronchus_Control_(B.)\|World / Sample group, Lineage and Cell type	KRT5 NBEA ATP10B CMYA5 ERN2 PRDM2	1.10e-04	197	170	6	b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Basal_1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	KRT5 PTP4A3 DST CLCNKA CLCNKB RAB13	1.14e-04	198	170	6	f632342e1e8911dd82b5df171776a84c7dc3f931
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C ADAMTS1 NTRK3 ADCY3 FRY PTP4A3	1.14e-04	198	170	6	7dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCell	Parenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C ADAMTS1 ADAMTS5 ADCY3 LY9 NR1H4	1.14e-04	198	170	6	882710bd6215e299257dd3df234292db9a2823ba
ToppCell	metastatic_Brain-Endothelial_cells\|metastatic_Brain / Location, Cell class and cell subclass	ADAMTS1 PPFIBP1 ADAMTS5 ABCB1 FRY DCHS1	1.14e-04	198	170	6	97ef7946ef11ac93318c1dd46b548dc01e5a6aba
ToppCell	metastatic_Brain-Endothelial_cells-Tumor_ECs\|metastatic_Brain / Location, Cell class and cell subclass	ADAMTS1 PPFIBP1 ADAMTS5 ABCB1 FRY DCHS1	1.14e-04	198	170	6	5e274f29cc796dae7d64d6035e904816c25f9914
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PDGFRA ADAMTS1 ADAMTS5 ITGA9 DST PLXNA4	1.17e-04	199	170	6	e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PDGFRA ADAMTS1 LAMA1 COL6A5 DST PLXNA4	1.17e-04	199	170	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PDGFRA ADAMTS1 LAMA1 COL6A5 DST PLXNA4	1.20e-04	200	170	6	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	PDGFRA ADAMTS1 NBEA ADAMTS5 ITGA9 PLXNA4	1.20e-04	200	170	6	a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC3 GIPC2 PPFIBP1 ABCB1 SLC16A4 DNM1	1.20e-04	200	170	6	105564ee05bd11685b5747ee32d5350cf3c2e2e1
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	PDGFRA ADAMTS1 ADAMTS5 ITGA9 DST PLXNA4	1.20e-04	200	170	6	02cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	PDGFRA ADAMTS1 LAMA1 COL6A5 DST PLXNA4	1.20e-04	200	170	6	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ADAMTS1 NTRK3 ADAMTS5 ITGA9 DST PLXNA4	1.20e-04	200	170	6	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
Drug	2'(3')-O-(2,4,6-trinitrophenyl)-ADP	ABCB5 ABCB1 GLUD1 GLUD2	1.96e-07	8	168	4	CID000644359
Drug	erysolin	ABCB5 ABCB1 DNM1	1.57e-06	4	168	3	CID003080557
Drug	NSC695241	ABCC3 ABCB5 ABCB1	7.77e-06	6	168	3	CID000003584
Drug	Tetracycline	ABCC3 NRDC ABCB5 GPAT3 FAS ABCB1 ACSL1 CROT SQSTM1 GLUD1 PRKAB2 ABCD3 PIP4K2B HADHA ABCG8 TAT NR1H4	9.70e-06	668	168	17	ctd:D013752
Drug	AC1MRGT8	ABCC3 ATP7A ABCB5 MC2R OCA2 ABCB1	1.01e-05	67	168	6	CID003517815
Drug	DB02841	ABCB5 OCA2 ABCB1 ABCG4 ABCD3 PIP4K2B	1.11e-05	68	168	6	CID005288987
Drug	O746	ABCC3 ABCB5 ABCB1 CROT	1.26e-05	20	168	4	CID006327063
Drug	Fenofibrate	ABCC3 ITCH GPAT3 FAS ABCB1 ACSL1 SLC7A1 BNIP3 SQSTM1 PRKAB2 ABCD3 NCEH1 HADHA HECTD1 ABCG8 NR1H4	1.64e-05	624	168	16	ctd:D011345
Drug	AC1Q5X3R	ABCC3 ABCB5 ABCB1 USP6	1.89e-05	22	168	4	CID000108075
Drug	nicotine glucuronide	ABCC3 ABCB5 ABCB1	2.15e-05	8	168	3	CID003035848
Drug	AC1MQ2IK	ACSL1 GLUD1 GLUD2	2.15e-05	8	168	3	CID003394958
Drug	NHS-ASA	ABCB1 GLUD1 GLUD2	3.21e-05	9	168	3	CID003035647
Drug	yttrium	GPAT3 ABCB1 CROT DNAH5 NR1H4	3.68e-05	51	168	5	CID000023993
Drug	thioxanthene	ABCB5 ABCB1 TAT	4.56e-05	10	168	3	CID000067495
Drug	S884	CACNA1C GLUD1 GLUD2	4.56e-05	10	168	3	CID004685067
Drug	azoxystrobin	SYNRG MC2R HPS3 GLUD1 GLUD2 NCEH1	4.85e-05	88	168	6	CID003034285
Drug	Bezafibrate	FAS ABCB1 ACSL1 BMP2 CROT BNIP3 ABCD3 HADHA NR1H4	5.33e-05	229	168	9	ctd:D001629
Drug	phenyltriethoxysilane	GLUD1 GLUD2	5.41e-05	2	168	2	CID000013075
Drug	mesochlorin e6 monoethylenediamine	ABCB5 ABCB1	5.41e-05	2	168	2	CID005488855
Drug	taxuspine C	ABCB5 ABCB1	5.41e-05	2	168	2	CID005321745
Drug	G-3SH	GLUD1 GLUD2	5.41e-05	2	168	2	CID000174237
Drug	2,2-diphenyl-1,3-dioxolane	ABCB5 ABCB1	5.41e-05	2	168	2	CID000283230
Drug	iodoacetyldiethylstilbestrol	GLUD1 GLUD2	5.41e-05	2	168	2	CID006455327
Drug	Ro44-5912	ABCB5 ABCB1	5.41e-05	2	168	2	CID000197370
Drug	methylmercuric bromide	GLUD1 GLUD2	5.41e-05	2	168	2	CID000068175
Drug	5-methylisophthalate	GLUD1 GLUD2	5.41e-05	2	168	2	CID000068137
Drug	8-(3,3-dimethylallyl)chrysin	ABCB5 ABCB1	5.41e-05	2	168	2	CID005281903
Drug	AC1L8LCS	ABCB5 ABCB1	5.41e-05	2	168	2	CID000383419
Drug	sulfurmycin A	ABCB5 ABCB1	5.41e-05	2	168	2	CID000155836
Drug	DAPDOX	ABCB5 ABCB1	5.41e-05	2	168	2	CID000164413
Drug	AC1Q6JJG	ABCB5 ABCB1	5.41e-05	2	168	2	CID000164322
Drug	YM212	ABCB5 ABCB1	5.41e-05	2	168	2	CID000129980
Drug	Ro11-2933	ABCB5 ABCB1	5.41e-05	2	168	2	CID000115215
Drug	cnidiadin	ABCB5 ABCB1	5.41e-05	2	168	2	CID005315980
Drug	conferone	ABCB5 ABCB1	5.41e-05	2	168	2	CID001757335
Drug	x 1 s	GLUD1 GLUD2	5.41e-05	2	168	2	CID000409694
Drug	VX-710-3	ABCB5 ABCB1	5.41e-05	2	168	2	CID006450549
Drug	NAc-LLY-amide	ABCB5 ABCB1	5.41e-05	2	168	2	CID000443109
Drug	62820-12-6	ABCB5 ABCB1	5.41e-05	2	168	2	CID006449905
Drug	3 alpha,6 alpha-dihydroxy-5 beta-cholanoic acid	ABCC3 ABCB5 ABCB1 NR1H4	5.88e-05	29	168	4	CID000006747
Drug	NSC648766	ABCC3 ATP7A PDGFRA ABCB5 ABCB1 CCNB2	6.62e-05	93	168	6	CID000003199
Drug	17-AAG; Up 200; 1uM; HL60; HT_HG-U133A	P4HA2 ATP10B SPPL2B FAS AHSA1 FANCA MICAL2 TBX10	6.65e-05	183	168	8	6185_UP
Drug	Lithocholic Acid	ABCC3 FAS ABCB1 ACSL1 TGFBR1 CROT GNAT3 ABCG8 NR1H4	7.65e-05	240	168	9	ctd:D008095
Drug	nitroparacetamol	FAS GLUD1 GLUD2	8.27e-05	12	168	3	CID006918532
Drug	Deoxycholic Acid	ABCC3 ABCB1 CROT BNIP3 GUCA1A ABCG8 NR1H4	8.67e-05	141	168	7	ctd:D003840
Drug	chloroacetaldehyde	ABCC3 PPFIBP1 GPAT3 FAS POLR3F ACSL1 SLC7A1 BNIP3 SQSTM1 PRKAB2	9.89e-05	307	168	10	ctd:C004656
Drug	Harmine hydrochloride [343-27-1]; Up 200; 16uM; PC3; HT_HG-U133A	PLXNA3 ABCC3 ATP10B PRDM2 PCF11 BMP2 RBM25 MICAL2	1.00e-04	194	168	8	5855_UP
Drug	biochanin A	ABCB5 ABCB1 ARID3B SLC7A1 CCNB2 DNM1	1.05e-04	101	168	6	CID005280373
Drug	5-carboxyfluorescein diacetate	ABCC3 ABCB5 ABCB1	1.07e-04	13	168	3	CID000133314
Drug	THDCA	ABCB5 ABCB1 NR1H4	1.07e-04	13	168	3	CID000119046
Drug	phylloerythrin	ABCB1 GLUD1 GLUD2	1.07e-04	13	168	3	CID005480977
Drug	TNP-GTP	ABCB1 GLUD1 GLUD2	1.07e-04	13	168	3	CID000126171
Drug	Famprofazone [22881-35-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A	ACVR1B ERN2 MAST2 PTP4A3 MICAL2 SCAPER PIP4K2B TAT	1.07e-04	196	168	8	6029_DN
Drug	(+/-)-verapamil hydrochloride; Up 200; 10uM; MCF7; HG-U133A	PLXNA3 NTRK3 CNTNAP1 ATP10B ERN2 SCAPER NIPBL PLXNA1	1.15e-04	198	168	8	161_UP
Drug	estradiol, USP; Down 200; 0.01uM; MCF7; HG-U133A	SYNRG PPFIBP1 CNTNAP1 ERN2 MAST2 PRDM2 TGFBR1 RAD54L	1.15e-04	198	168	8	121_DN
Drug	Glafenine hydrochloride [65513-72-6]; Up 200; 9.8uM; MCF7; HT_HG-U133A	LZTR1 ERN2 MAST2 PRDM2 DDX6 SLC7A1 TRANK1 SCAPER	1.15e-04	198	168	8	7018_UP
Drug	Repaglinide [135062-02-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A	PPFIBP1 TNPO2 SPPL2B ERN2 ADCY3 PTK6 SQSTM1 PLSCR3	1.19e-04	199	168	8	3558_DN
Drug	Buspirone hydrochloride [33386-08-2]; Down 200; 9.4uM; HL60; HT_HG-U133A	SPPL2B ERN2 ADCY3 PRDM2 POLR3F PTP4A3 PIP4K2C LY9	1.23e-04	200	168	8	1282_DN
Drug	tetramethylrosamine	ABCC3 ABCB5 ABCB1	1.35e-04	14	168	3	CID000443313
Drug	2-chloroquinazoline	ABCB5 ABCB1	1.62e-04	3	168	2	CID000074054
Drug	fluoroanilinoazatoxin	ABCB5 ABCB1	1.62e-04	3	168	2	CID000378896
Drug	Dihydrocyclosporin C	ABCB5 ABCB1	1.62e-04	3	168	2	CID000196411
Drug	NSC82591	ABCB5 ABCB1	1.62e-04	3	168	2	CID000579054
Drug	CID5317124	ABCB5 ABCB1	1.62e-04	3	168	2	CID005317124
Drug	NSC688503	ABCB5 ABCB1	1.62e-04	3	168	2	CID000390744
Drug	Cp-100356	ABCB5 ABCB1	1.62e-04	3	168	2	CID000196918
Drug	BIBW22BS	ABCB5 ABCB1	1.62e-04	3	168	2	CID000132088
Drug	AC1NSGRQ	ABCB5 ABCB1	1.62e-04	3	168	2	CID005333904
Drug	taxinine	ABCB5 ABCB1	1.62e-04	3	168	2	CID005321702
Drug	Hapalosin	ABCB5 ABCB1	1.62e-04	3	168	2	CID000133055
Drug	haemanthidine	ABCB5 ABCB1	1.62e-04	3	168	2	CID000124066
Drug	taccalonolide A	ABCB5 ABCB1	1.62e-04	3	168	2	CID000441685
Drug	taccalonolide E	ABCB5 ABCB1	1.62e-04	3	168	2	CID005321583
Drug	lenthionine	GLUD1 GLUD2	1.62e-04	3	168	2	CID000067521
Drug	iodomycin	ABCB5 ABCB1	1.62e-04	3	168	2	CID000149155
Drug	mildiomycin	GLUD1 GLUD2	1.62e-04	3	168	2	CID000125665
Drug	R101933	ABCB5 ABCB1	1.62e-04	3	168	2	CID000219080
Drug	methylazatoxin	ABCB5 ABCB1	1.62e-04	3	168	2	CID000148162
Drug	dendroamide A	ABCB5 ABCB1	1.62e-04	3	168	2	CID000177307
Drug	methoxyethylmercury	GLUD1 GLUD2	1.62e-04	3	168	2	CID000115155
Drug	4-methylumbelliferyl laurate	GLUD1 GLUD2	1.62e-04	3	168	2	CID000600674
Drug	Wp159	ABCB5 ABCB1	1.62e-04	3	168	2	CID003060549
Drug	AC1L2Z11	ABCB5 ABCB1	1.62e-04	3	168	2	CID000080228
Drug	methylmercuric iodide	GLUD1 GLUD2	1.62e-04	3	168	2	CID000067347
Drug	NK-250	ABCB5 ABCB1	1.62e-04	3	168	2	CID000164220
Drug	5-N-acetylardeemin	ABCB5 ABCB1	1.62e-04	3	168	2	CID000127303
Drug	1-bromo-4-chlorobutane	ABCB5 ABCB1	1.62e-04	3	168	2	CID000081364
Drug	D-Val-Thz	ABCB5 ABCB1	1.62e-04	3	168	2	CID003082826
Drug	AC1L87CG	ABCB5 ABCB1	1.62e-04	3	168	2	CID000373763
Drug	PAK-104P	ABCC3 ABCB5 ABCB1	1.68e-04	15	168	3	CID000131368
Drug	Metformin	ABCC3 PPFIBP1 GPAT3 FAS ABCB1 POLR3F ACSL1 SLC7A1 BNIP3 SQSTM1 PRKAB2	1.97e-04	400	168	11	ctd:D008687
Drug	carvedilol	SYNRG ABCB5 FAS ADCY3 ABCB1 BMP2 NR1H4	1.98e-04	161	168	7	CID000002585
Drug	AC1L4BIC	ABCC3 ABCB5 ABCB1	2.06e-04	16	168	3	CID000153998
Drug	R-5	MC2R GLUD1 GLUD2	2.06e-04	16	168	3	CID011742733
Drug	AC1L1GHH	ABCC3 ABCB5 ABCB1 CCNB2 DNM1	2.20e-04	74	168	5	CID000003685
Drug	AC1L9A0M	PDGFRA LYZL4 ITGA9 DCHS1 SPACA5	2.20e-04	74	168	5	CID000440822
Drug	Cholic Acid	ABCC3 ABCB1 SQSTM1 ABCG8 NR1H4	2.34e-04	75	168	5	ctd:D019826
Drug	n-propionyl-CoA	NKRF ACSL1 CROT GLUD1 GLUD2 ABCD3 HADHA	2.39e-04	166	168	7	CID000001033
Drug	acridone	ABCB5 ABCB1 ACSL1	2.49e-04	17	168	3	CID000002015
Drug	Cholates	ABCC3 ABCG8 NR1H4	2.49e-04	17	168	3	ctd:D020355
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	ABCC3 ABCB1 HADHA ABCG8 NR1H4	2.97e-05	65	162	5	DOID:0080208 (biomarker_via_orthology)
Disease	Bartter disease type 4B	CLCNKA CLCNKB	3.00e-05	2	162	2	cv:C4310805
Disease	Bartter disease type 3 (implicated_via_orthology)	CLCNKA CLCNKB	3.00e-05	2	162	2	DOID:0110144 (implicated_via_orthology)
Disease	BARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS	CLCNKA CLCNKB	3.00e-05	2	162	2	613090
Disease	intellectual developmental disorder with hypotonia, impaired speech, and dysmorphic facies (implicated_via_orthology)	TNPO1 TNPO2	3.00e-05	2	162	2	DOID:0081262 (implicated_via_orthology)
Disease	BARTTER SYNDROME, TYPE 4B	CLCNKA CLCNKB	3.00e-05	2	162	2	C2751312
Disease	BARTTER SYNDROME, TYPE 4B, NEONATAL, WITH SENSORINEURAL DEAFNESS	CLCNKA CLCNKB	3.00e-05	2	162	2	C4310805
Disease	Bartter disease type 4b (is_implicated_in)	CLCNKA CLCNKB	3.00e-05	2	162	2	DOID:0110146 (is_implicated_in)
Disease	Bartter disease (implicated_via_orthology)	CLCNKA CLCNKB	3.00e-05	2	162	2	DOID:445 (implicated_via_orthology)
Disease	hepatic encephalopathy (biomarker_via_orthology)	ABCB1 GLUD1 GLUD2	7.04e-05	15	162	3	DOID:13413 (biomarker_via_orthology)
Disease	osteoarthritis (implicated_via_orthology)	ATP7A ADAMTS5 TGFBR1	7.04e-05	15	162	3	DOID:8398 (implicated_via_orthology)
Disease	phosphatidylcholine 38:6 measurement	ABCC3 AHCTF1 TMEM258	8.63e-05	16	162	3	EFO_0010388
Disease	EPIDERMOLYSIS BULLOSA SIMPLEX, AUTOSOMAL RECESSIVE (disorder)	KRT5 DST	8.95e-05	3	162	2	C1832926
Disease	fascioliasis (biomarker_via_orthology)	GLUD1 GLUD2	8.95e-05	3	162	2	DOID:885 (biomarker_via_orthology)
Disease	a disintegrin and metalloproteinase with thrombospondin motifs 5 measurement	ADAMTS1 ADAMTS5	8.95e-05	3	162	2	EFO_0008326
Disease	visual epilepsy (biomarker_via_orthology)	ADAMTS1 FAS ABCB1 GLUD1 GLUD2	1.41e-04	90	162	5	DOID:11832 (biomarker_via_orthology)
Disease	cholestasis (biomarker_via_orthology)	ABCC3 ABCB1 ABCG8 NR1H4	1.53e-04	49	162	4	DOID:13580 (biomarker_via_orthology)
Disease	Colorectal Neoplasms	ABCC3 TRPM7 ABCB5 LAMA1 ABCB1 TGFBR1 BMP2 ABCD3	1.55e-04	277	162	8	C0009404
Disease	brain ischemia (biomarker_via_orthology)	ADAMTS1 FAS ABCB1 GLUD1 GLUD2	2.54e-04	102	162	5	DOID:2316 (biomarker_via_orthology)
Disease	Epidermolysis Bullosa Simplex	KRT5 DST	2.96e-04	5	162	2	C0079298
Disease	pancreatic cancer (is_implicated_in)	PDGFRA ACVR1B ITGA9 FANCA RAD54L	3.92e-04	112	162	5	DOID:1793 (is_implicated_in)
Disease	childhood absence epilepsy (biomarker_via_orthology)	GLUD1 GLUD2	4.43e-04	6	162	2	DOID:1825 (biomarker_via_orthology)
Disease	Bartter syndrome	CLCNKA CLCNKB	4.43e-04	6	162	2	cv:C0004775
Disease	Adenine measurement	CACNA1C GIPC2	6.18e-04	7	162	2	EFO_0021573
Disease	epidermolysis bullosa simplex (is_implicated_in)	KRT5 DST	6.18e-04	7	162	2	DOID:4644 (is_implicated_in)
Disease	temporal lobe epilepsy (biomarker_via_orthology)	ABCB1 GLUD1 GLUD2	6.52e-04	31	162	3	DOID:3328 (biomarker_via_orthology)
Disease	Cholestasis of pregnancy	ABCG8 NR1H4	8.21e-04	8	162	2	C0268318
Disease	familial hyperlipidemia (is_implicated_in)	ABCB1 ABCG8	8.21e-04	8	162	2	DOID:1168 (is_implicated_in)
Disease	chemotherapy-induced alopecia, response to docetaxel trihydrate	ABCB1 SLC52A3	8.21e-04	8	162	2	EFO_0005400, GO_1902519
Disease	Todd Paralysis	ATP7A TRPM7	1.05e-03	9	162	2	C0234544
Disease	Paralysed	ATP7A TRPM7	1.05e-03	9	162	2	C0522224
Disease	Osteitis Deformans	NUP205 SQSTM1	1.05e-03	9	162	2	C0029401
Disease	retinal detachment (biomarker_via_orthology)	FAS BNIP3	1.05e-03	9	162	2	DOID:5327 (biomarker_via_orthology)
Disease	cystic fibrosis (implicated_via_orthology)	ABCB5 ABCB1	1.05e-03	9	162	2	DOID:1485 (implicated_via_orthology)
Disease	sporadic amyotrophic lateral sclerosis	ITGA9 METTL21A MYOM2 HADHA PLXNA1	1.08e-03	140	162	5	EFO_0001357
Disease	Liver Cirrhosis, Experimental	SYNRG PDGFRA CCDC126 NBEA FAS ABCB1 ACSL1 SLC7A1 FRY CROT CCNB2 ABCG8	1.22e-03	774	162	12	C0023893
Disease	nephrogenic diabetes insipidus (implicated_via_orthology)	CLCNKA CLCNKB	1.31e-03	10	162	2	DOID:12387 (implicated_via_orthology)
Disease	age of onset of depressive disorder, wellbeing measurement	CMYA5 PTPDC1	1.31e-03	10	162	2	EFO_0007869, OBA_2040166
Disease	3-phenylpropionate hydrocinnamate measurement	LAMA1 TTC6	1.31e-03	10	162	2	EFO_0021010
Disease	Bardet-Biedl syndrome (implicated_via_orthology)	TBC1D32 SCAPER	1.59e-03	11	162	2	DOID:1935 (implicated_via_orthology)
Disease	Colorectal Carcinoma	ABCC3 TRPM7 ABCB5 LAMA1 HPS3 ABCB1 TGFBR1 BMP2 LIG1 ABCD3 DCHS1	1.79e-03	702	162	11	C0009402
Disease	end stage renal disease (biomarker_via_orthology)	ABCC3 ABCB1 BNIP3	2.21e-03	47	162	3	DOID:783 (biomarker_via_orthology)
Disease	acute myeloid leukemia (is_marker_for)	ABCC3 FAS BRD7	2.49e-03	49	162	3	DOID:9119 (is_marker_for)
Disease	skin melanoma (is_implicated_in)	OCA2 FANCA	2.61e-03	14	162	2	DOID:8923 (is_implicated_in)
Disease	Hepatomegaly	ABCC3 ADAMTS5 NR1H4	3.28e-03	54	162	3	C0019209
Disease	cochlin measurement	COPZ1 G2E3	3.42e-03	16	162	2	EFO_0801481
Disease	Intrahepatic cholestasis of pregnancy	ABCB1 ABCG8	3.42e-03	16	162	2	EFO_0009048
Disease	ecosanoids measurement	ABCC3 TMEM258 ABCG8	3.46e-03	55	162	3	EFO_0020044
Disease	DNA methylation	DNHD1 MC2R OCA2 ACVR1B ACSL1 FRY MROH2B PLXNA4 DCHS1 USP6NL	3.48e-03	656	162	10	GO_0006306
Disease	Uremia	TGFBR1 BMP2	3.86e-03	17	162	2	C0041948
Disease	mean platelet volume	TNPO1 CUL4A NRDC COPZ1 DOCK11 PCDHGA11 FANCA ACSL1 FRY PTP4A3 TRANK1 ABCG8 ATP5F1B	4.25e-03	1020	162	13	EFO_0004584
Disease	alcoholic hepatitis (biomarker_via_orthology)	FAS NR1H4	4.33e-03	18	162	2	DOID:12351 (biomarker_via_orthology)
Disease	skin sensitivity to sun	OCA2 FANCA	4.82e-03	19	162	2	EFO_0004795
Disease	ovulation	FANCA ACSL1	4.82e-03	19	162	2	GO_0030728

Protein segments in the cluster

Peptide	Gene	Start	Entry
MLYKLVTEKGGLVEI	ARID3B	251	Q8IVW6
KSAELAAALLSIYME	ESYT1	791	Q9BSJ8
YEINLMEELTLKGVT	DDX6	296	P26196
VEDAKLYMDFLVLGI	ABCG4	611	Q9H172
DYMAVLIKDDGTLQL	CNTNAP1	1106	P78357
IVGINLTEMAYSLLK	ELMOD2	206	Q8IZ81
EKYMEEIVESTLSLL	TBC1D32	311	Q96NH3
PYVMADSLLDVLTKG	BRD7	456	Q9NPI1
VKLLREAMGIYISTL	AHSA1	141	O95433
LKIIVVMDAYGSELV	ACSL1	221	P33121
MGYSATKEILIVQIL	ADAMTS5	821	Q9UNA0
MAIGETLVLAPEYSK	ABCB5	966	Q2M3G0
RYTVTIEGMIKLALS	ACVR1B	296	P36896
EMAVKYISEVALALD	MASTL	131	Q96GX5
AGMSVDRYLAVVKLL	GPR25	131	O00155
EMYLSKGLLLIFVVD	ARL9	81	Q6T311
GDKILSVMELDSYPL	ABCG8	626	Q9H221
LYALSIKDSVMVLSA	PRKAB2	241	O43741
AIEKIDDVLELYMGI	GIPC2	246	Q8TF65
VELEGIIMSLESVLY	DNHD1	1336	Q96M86
LIAMSSIYLAGKVEE	CCNQ	71	Q8N1B3
LSAISMLYLDENEKV	BMP2	366	P12643
VVYTKGADSVIMDLL	ATP10B	786	O94823
YKSLQDIIAILGMDE	ATP5F1B	431	P06576
VMLALLVSVSAEGYK	ANO8	401	Q9HCE9
IYSILVALMAGKAEV	ATP7A	516	Q04656
VILGMKLTSDEKYLV	NWD2	1011	Q9ULI1
AMGIILVYDITDEKS	RAB13	81	P51153
MIKGAIEVLIREYSS	RBM25	206	P49756
IEYVGEQTALLIKMV	OCA2	701	Q04671
ELSSLYVGLKESMKD	QRICH2	1036	Q9H0J4
GKMLVLDYILAVTRS	RAD54L	496	Q92698
STLEQDIMYKGVVLR	ADAMTS1	786	Q9UHI8
NMELLVEDTLKIYGV	PCDHGA11	106	Q9Y5H2
TIMDYTRVLVLDKGV	ABCC3	1486	O15438
IGELKMTQEEYALLT	NR1H4	386	Q96RI1
ELMEQGLTYKVLTLV	NUP205	176	Q92621
LMAKALLLYGADIES	POTEB2	216	H3BUK9
LDKLYMVVGTLAAII	ABCB1	46	P08183
TSELDLEMEALKTVY	PDGFRA	211	P16234
ELYILKVMAVSGSKA	DCHS1	1066	Q96JQ0
QLTLLGTEMDYVEDK	ISCA1	91	Q9BUE6
SSIDKDVIVALMYTV	OR1J2	266	Q8NGS2
LMNAKLGLDIEIATY	KRT84	451	Q9NSB2
ITHDGMVYLADVLKS	LRRC34	306	Q8IZ02
ILAIVKAMTTLGIDY	GNAT3	81	A8MTJ3
MKASVVLSLLGYLVV	LYZL4	1	Q96KX0
LATLMVVTVDAKIYE	SPACA5	11	Q96QH8
DIGTSLIQDMKAYLE	LZTR1	646	Q8N653
LYKTLAESMGIEVKL	TAT	171	P17735
DSNLKYILVMDISPV	MGA	116	Q8IWI9
AVDMELYTGLQKLTI	NTRK3	96	Q16288
MELPDYVLLTATAKV	PPFIBP1	886	Q86W92
ILIEDETSIQKMYLG	DST	2831	Q03001
MYHALKEALSIIGDI	DNM1	731	Q05193
DTQLLMTLYVGKDET	ERN2	281	Q76MJ5
LMNTKLALDVEIATY	KRT5	456	P13647
LESHGLAYSIMIKDI	CPA5	96	Q8WXQ8
AAVGYIMEKADLVIV	EIF2B1	181	Q14232
VKAVLLGATFLIDYM	PLSCR3	266	Q9NRY6
MEYATGVLKQLLSDL	PLXNA1	1401	Q9UIW2
GSKMVSEIYLTRLLA	PLXNA1	1671	Q9UIW2
GSKMVSEIYLTRLLA	PLXNA3	1646	P51805
MTVLQSKLEYATDVL	PLXNA4	1391	Q9HCM2
MYAKRLESAGVEVTL	NCEH1	356	Q6PIU2
AKTDVTMLLYIADNL	NIPBL	2421	Q6KC79
MEALILEPSLYTVKA	COPZ1	1	P61923
KLVAAYILGLITMAI	MOSPD1	196	Q9UJG1
VLYIYKELEGALSTM	LCN15	121	Q6UWW0
DYGVASLTTILDMVK	PTPDC1	161	A2A3K4
YLVETSLRTGSEKIM	MIER3	221	Q7Z3K6
SQLDSELMDITKLYG	NUP155	1176	O75694
YIITELMAKGSLLEL	PTK6	261	Q13882
SIGHMTDLIYAEKEL	P4HA2	26	O15460
LMDSIVKNVGREYLT	PCF11	76	O94913
IVLSTYLEMGAVELR	METTL21A	51	Q8WXB1
YVLSLEIGKTLMEDV	PPT1	66	P50897
LLSSMDEKTLYLALG	ITGA9	636	Q13797
LEMYFSVDKEILGEI	ITCH	701	Q96J02
IYLMDTSGKVVTATL	RPA1	346	P27694
TTLSDKYMLVKDILG	G2E3	531	Q7L622
ATVESLEQYLLKMVA	HECTD1	1026	Q9ULT8
MTKSLENILTLAGEY	FBH1	931	Q8NFZ0
VSIYNGDMEKILLDA	BNIP3	36	Q12983
YLTDMAVLVLEVITK	C2CD3	106	Q4AC94
LEIILKMTAYGAFLH	CACNA1C	966	Q13936
EIIAKSMATYLLEEN	DOCK11	966	Q5JSL3
MAGYADLKRTIAVLL	CCDC126	76	Q96EE4
VGITALLLASKYEEM	CCNB2	211	O95067
SLGISEIYMKILVKT	GPAT3	31	Q53EU6
LVEKAYASIRGVAME	COL20A1	851	Q9P218
VSVDEVKALASLMTY	GLUD1	156	P00367
LKVSIENMGLYEDLS	FANCA	521	O15360
SLLGMLSDLQVYKDS	CUL4A	216	Q13619
GSETATDLMQKLYLL	COL6A5	2561	A8TX70
EIQSYSLIGEKLVME	CMYA5	2316	Q8N3K9
GLAMVEAISYVREKT	ADCY3	391	O60266
LMDNLFKYVIGTLEL	BNIP2	186	Q12982
IDFMEYVAALSLVLK	GUCA1A	71	P43080
VTIMVKSYLGRLDIT	LY9	96	Q9HBG7
LSKIGLMSLTTNLYE	MAST2	656	Q6P0Q8
DKGLVEKLTAYAMTI	HADHA	261	P40939
ALIMGEYIFALKDLT	KNDC1	916	Q76NI1
IELKLSSYEEMLQSV	EXOC1	231	Q9NV70
MYLLDGVTEAAKHSI	AHCTF1	761	Q8WYP5
LNMVTYLAELLEKGL	FRY	2221	Q5TBA9
TILLKAAELGMVSAY	GRIK4	226	Q16099
GLMVKTLDVDATYEI	LIG1	721	P18858
DLISYVVNMGLIDKL	SCAPER	1101	Q9BY12
GFAIMLVIALYEDKI	SLC39A10	811	Q9ULF5
VSVDEVKALASLMTY	GLUD2	156	P49448
LILENYGADIDMISK	DNAH5	591	Q8TE73
RAAILMKGTAAILEY	LRRC40	581	Q9H9A6
KGVIINDYIDTEMLL	MICAL2	311	O94851
SEELYTTIKIMASGI	PRDM2	1266	Q13029
LEKIQSSLLVYSMED	CROT	266	Q9UKG9
LKIMDYSLLLGIHDI	PIP4K2C	276	Q8TBX8
LTLKTTEMETIYDLG	RUVBL2	161	Q9Y230
MVEDLAASYIVLKLE	RTL3	1	Q8N8U3
YLGTFLKDLVMLDAA	RGL2	431	O15211
GIDEYLMKRVTQTLI	TIGD6	496	Q17RP2
SYVKVMLGVVLRDLS	SLC52A3	411	Q9NQ40
ETYVGQEMLKLSIID	TMC3	501	Q7Z5M5
DMKIGSEELVYITHI	TDRD6	981	O60522
KYLMELGNALETILS	TMCO4	316	Q5TGY1
TKEELYTVLAMIAVT	SYNRG	351	Q9UMZ2
GYVAVMSDLEVLIVK	HPS3	196	Q969F9
IDIGEMPSYDLVLSK	NKRF	11	O15226
LYSMSLLEDKGLAEV	SCPEP1	216	Q9HB40
KTTTLALMFGLYEDL	SLC25A51	91	Q9H1U9
LMAKALLLYGADIES	POTEB	216	A0A0A6YYL3
MSVLSDIEYILIKAS	LAMA1	1311	P25391
MLGVLASYSITVKEL	NBEA	181	Q8NFP9
LAQLKIMDYSLLVGI	PIP4K2B	271	P78356
LMAKALLLYGADIES	POTEJ	216	P0CG39
ETILNTLIYDGKVEM	POLR3F	236	Q9H1D9
TLIYDGKVEMTIIAA	POLR3F	241	Q9H1D9
KTTTLALMFGLYEDL	SLC25A52	91	Q3SY17
LTKTDVMVIYGAVAL	MROH2B	696	Q7Z745
MASLTVKAYLLGKED	SQSTM1	1	Q13501
ISEGTTLKDLIYDMT	TGFBR1	171	P36897
DVLSVADMYLLPGLK	ABTB1	351	Q969K4
KETGYLVLIAVMLVS	ABCD3	81	P28288
LAISDMLGSLYKILE	MC2R	66	Q01718
LYELKAAVDGLSKMI	AIMP2	66	Q13155
LYDMLASIKSGDELQ	ASCC3	251	Q8N3C0
LGLTVTLIKYQELME	CLEC17A	186	Q6ZS10
LKTMLAGVILEDYLD	CLCNKA	126	P51800
VKTMLAGVVLEDYLD	CLCNKB	126	P51801
KILGMDSLADYALLM	TBX10	101	O75333
EGERVLTAMSYTILK	USP6NL	291	Q92738
ALALIESGMKYEDAI	PTP4A3	116	O75365
LEDYVVLMKRGTAIT	TRMT61B	216	Q9BVS5
TIYQIAEMDKGLSEL	TTC6	11	Q86TZ1
AKTLGIDIMDASYLV	SLC16A4	326	O15374
DVDLSKYITTIAGVM	FAS	226	P25445
KDLVDLMSIGTLLAY	SLC7A1	406	P30825
ILVNGMKYSEIDIIL	TNPO2	301	O14787
IGIPVALLSYKDMLD	SPPL2B	136	Q8TCT7
KYQALMDGLSLESLL	NRDC	831	O43847
ASVYDEAMELIVKLA	RIOK2	206	Q9BVS4
VLVNGMKYSDIDIIL	TNPO1	311	Q92973
KATLYAVLVSALVLM	TRB	291	P0DTU4
YKELLISLVASLFMG	TMEM258	51	P61165
LKEIDYILSTDMYGL	TRANK1	2206	O15050
YIDLDELKIMLQATG	TNNC1	111	P63316
KALEVDSYKSLMILG	PNMA8C	16	A0A1B0GUJ8
KITLIDIGLVIEYLM	TRPM7	506	Q96QT4
YMDLEITVIKLDGTT	USP6	716	P35125
DSYMHLEITVIKLDG	USP32	916	Q8NFA0
KIIVYLSDTTLMDIL	WDR81	1351	Q562E7
SILEIAGKVYDDMIL	MYOM2	1211	P54296