Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	threonine-tRNA ligase activity	TARS3 TARS1	7.88e-05	3	103	2	GO:0004829
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	PCDHA9 DSC2 PCDHB2 PCDHA4 HMCN2 CNTN5 PVR ROBO1 IGSF9	3.79e-07	187	102	9	GO:0007156
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	PCDHA9 DSC2 PCDHB2 PCDHA4 CLDN11 HMCN2 CNTN5 PVR ROBO1 IGSF9 UNC5D	4.31e-07	313	102	11	GO:0098742
GeneOntologyBiologicalProcess	cell-cell adhesion	BOC NPHS1 PCDHA9 DSC2 LILRB2 PCDHB2 PCDHA4 SVEP1 ITPKB CLDN11 HMCN2 CNTN5 PVR ROBO1 IGSF9 UBASH3B UNC5D	2.02e-05	1077	102	17	GO:0098609
GeneOntologyBiologicalProcess	threonyl-tRNA aminoacylation	TARS3 TARS1	7.24e-05	3	102	2	GO:0006435
GeneOntologyBiologicalProcess	axonogenesis	BOC SZT2 PLXND1 TSKU HMCN2 SEMA5B CNTN5 ROBO1 IGSF9 UNC5D PLXNB1	1.13e-04	566	102	11	GO:0007409
GeneOntologyCellularComponent	nuclear membrane	NUP50 IL15RA RTEL1 SHISA5 DTL MAD2L1BP NAV3 ATP2A3	3.34e-04	349	103	8	GO:0031965
GeneOntologyCellularComponent	basement membrane	NPHS1 FREM2 HMCN2 NID1 USH2A	3.46e-04	122	103	5	GO:0005604
GeneOntologyCellularComponent	cerebellar granule cell to Purkinje cell synapse	GRM4 GRID2IP	4.97e-04	7	103	2	GO:0150048
Domain	Ig-like_fold	BOC NPHS1 IL10RB TSPOAP1 VASN LILRB2 PLXND1 MST1R HMCN2 CNTN5 PVR ALPK3 ROBO1 IGSF9 USH2A UNC5D PLXNB1	1.42e-07	706	98	17	IPR013783
Domain	FN3	BOC NPHS1 IL10RB TSPOAP1 VASN CNTN5 ROBO1 IGSF9 USH2A	5.57e-07	185	98	9	SM00060
Domain	FN3	BOC NPHS1 IL10RB TSPOAP1 VASN CNTN5 ROBO1 IGSF9 USH2A	1.03e-06	199	98	9	PS50853
Domain	FN3_dom	BOC NPHS1 IL10RB TSPOAP1 VASN CNTN5 ROBO1 IGSF9 USH2A	1.54e-06	209	98	9	IPR003961
Domain	-	BOC NPHS1 IL10RB TSPOAP1 VASN PLXND1 MST1R CNTN5 PVR ALPK3 ROBO1 IGSF9 USH2A UNC5D PLXNB1	1.82e-06	663	98	15	2.60.40.10
Domain	fn3	BOC NPHS1 TSPOAP1 VASN CNTN5 ROBO1 IGSF9 USH2A	2.19e-06	162	98	8	PF00041
Domain	Ig_I-set	BOC NPHS1 HMCN2 CNTN5 ALPK3 ROBO1 IGSF9 UNC5D	7.13e-06	190	98	8	IPR013098
Domain	I-set	BOC NPHS1 HMCN2 CNTN5 ALPK3 ROBO1 IGSF9 UNC5D	7.13e-06	190	98	8	PF07679
Domain	Sema	PLXND1 MST1R SEMA5B PLXNB1	2.01e-05	31	98	4	SM00630
Domain	Semap_dom	PLXND1 MST1R SEMA5B PLXNB1	2.01e-05	31	98	4	IPR001627
Domain	Sema	PLXND1 MST1R SEMA5B PLXNB1	2.01e-05	31	98	4	PF01403
Domain	SEMA	PLXND1 MST1R SEMA5B PLXNB1	2.01e-05	31	98	4	PS51004
Domain	PSI	PLXND1 MST1R SEMA5B PLXNB1	2.29e-05	32	98	4	PF01437
Domain	Plexin_repeat	PLXND1 MST1R SEMA5B PLXNB1	2.29e-05	32	98	4	IPR002165
Domain	IGc2	BOC NPHS1 HMCN2 CNTN5 ALPK3 ROBO1 IGSF9 UNC5D	3.31e-05	235	98	8	SM00408
Domain	Ig_sub2	BOC NPHS1 HMCN2 CNTN5 ALPK3 ROBO1 IGSF9 UNC5D	3.31e-05	235	98	8	IPR003598
Domain	IG	BOC NPHS1 LILRB2 HMCN2 CNTN5 PVR ALPK3 ROBO1 IGSF9 UNC5D	7.28e-05	421	98	10	SM00409
Domain	Ig_sub	BOC NPHS1 LILRB2 HMCN2 CNTN5 PVR ALPK3 ROBO1 IGSF9 UNC5D	7.28e-05	421	98	10	IPR003599
Domain	ThrRS_core	TARS3 TARS1	8.15e-05	3	98	2	IPR033728
Domain	Thr-tRNA-ligase_IIa	TARS3 TARS1	8.15e-05	3	98	2	IPR002320
Domain	PSI	PLXND1 MST1R SEMA5B PLXNB1	8.24e-05	44	98	4	IPR016201
Domain	PSI	PLXND1 MST1R SEMA5B PLXNB1	9.82e-05	46	98	4	SM00423
Domain	-	GTF2IRD2B GTF2IRD2	1.62e-04	4	98	2	3.90.1460.10
Domain	GFP	HMCN2 NID1	1.62e-04	4	98	2	IPR009017
Domain	G2F	HMCN2 NID1	1.62e-04	4	98	2	PF07474
Domain	GTF2I	GTF2IRD2B GTF2IRD2	1.62e-04	4	98	2	PS51139
Domain	GTF2I	GTF2IRD2B GTF2IRD2	1.62e-04	4	98	2	PF02946
Domain	GTF2I	GTF2IRD2B GTF2IRD2	1.62e-04	4	98	2	IPR004212
Domain	G2_nidogen/fibulin_G2F	HMCN2 NID1	1.62e-04	4	98	2	IPR006605
Domain	NIDOGEN_G2	HMCN2 NID1	1.62e-04	4	98	2	PS50993
Domain	IG_LIKE	BOC NPHS1 LILRB2 HMCN2 CNTN5 PVR ALPK3 ROBO1 IGSF9 UNC5D	2.55e-04	491	98	10	PS50835
Domain	Ig-like_dom	BOC NPHS1 LILRB2 HMCN2 CNTN5 PVR ALPK3 ROBO1 IGSF9 UNC5D	3.09e-04	503	98	10	IPR007110
Domain	CA	PCDHA9 DSC2 PCDHB2 PCDHA4 FREM2	3.49e-04	115	98	5	SM00112
Domain	-	DTL PLXND1 EDC4 ARHGEF17 SHKBP1 MST1R SEMA5B PLXNB1	3.67e-04	333	98	8	2.130.10.10
Domain	IPT	PLXND1 MST1R PLXNB1	3.74e-04	27	98	3	SM00429
Domain	WD40/YVTN_repeat-like_dom	DTL PLXND1 EDC4 ARHGEF17 SHKBP1 MST1R SEMA5B PLXNB1	3.82e-04	335	98	8	IPR015943
Domain	EGF_1	VASN SVEP1 HMCN2 NID1 NRG3 USH2A LTBP4	3.92e-04	255	98	7	PS00022
Domain	Cadherin	PCDHA9 DSC2 PCDHB2 PCDHA4 FREM2	3.93e-04	118	98	5	IPR002126
Domain	TGS	TARS3 TARS1	4.03e-04	6	98	2	IPR004095
Domain	TGS	TARS3 TARS1	4.03e-04	6	98	2	PF02824
Domain	TGS-like	TARS3 TARS1	5.63e-04	7	98	2	IPR012676
Domain	tRNA_SAD	TARS3 TARS1	5.63e-04	7	98	2	SM00863
Domain	tRNA_SAD	TARS3 TARS1	5.63e-04	7	98	2	IPR012947
Domain	tRNA_SAD	TARS3 TARS1	5.63e-04	7	98	2	PF07973
Domain	TIG	PLXND1 MST1R PLXNB1	5.66e-04	31	98	3	PF01833
Domain	IPT	PLXND1 MST1R PLXNB1	6.22e-04	32	98	3	IPR002909
Domain	Thr/Ala-tRNA-synth_IIc_edit	TARS3 TARS1	7.48e-04	8	98	2	IPR018163
Domain	Plexin_cytopl	PLXND1 PLXNB1	9.58e-04	9	98	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXND1 PLXNB1	9.58e-04	9	98	2	IPR013548
Domain	Plexin	PLXND1 PLXNB1	9.58e-04	9	98	2	IPR031148
Domain	HGTP_anticodon	TARS3 TARS1	9.58e-04	9	98	2	PF03129
Domain	EGF_CA	SVEP1 HMCN2 NID1 LTBP4	1.09e-03	86	98	4	PF07645
Domain	aa-tRNA-synt_IIb	TARS3 TARS1	1.45e-03	11	98	2	IPR002314
Domain	-	SVEP1 NID1	1.45e-03	11	98	2	2.40.155.10
Domain	GFP-like	SVEP1 NID1	1.45e-03	11	98	2	IPR023413
Domain	tRNA-synt_2b	TARS3 TARS1	1.45e-03	11	98	2	PF00587
Domain	-	TARS3 TARS1	1.45e-03	11	98	2	3.40.50.800
Domain	EGF_3	VASN SVEP1 HMCN2 NID1 NRG3 LTBP4	1.50e-03	235	98	6	PS50026
Domain	EGF_Ca-bd_CS	SVEP1 HMCN2 NID1 LTBP4	1.70e-03	97	98	4	IPR018097
Domain	EGF_CA	SVEP1 HMCN2 NID1 LTBP4	1.83e-03	99	98	4	PS01187
Domain	ASX_HYDROXYL	SVEP1 HMCN2 NID1 LTBP4	1.90e-03	100	98	4	PS00010
Domain	EGF-like_dom	VASN SVEP1 HMCN2 NID1 NRG3 LTBP4	2.00e-03	249	98	6	IPR000742
Domain	EGF-type_Asp/Asn_hydroxyl_site	SVEP1 HMCN2 NID1 LTBP4	2.35e-03	106	98	4	IPR000152
Domain	Beta-grasp_dom	TARS3 TARS1	2.38e-03	14	98	2	IPR012675
Domain	-	TARS3 TARS1	2.38e-03	14	98	2	3.10.20.30
Domain	Anticodon-bd	TARS3 TARS1	2.38e-03	14	98	2	IPR004154
Domain	EGF-like_CS	VASN SVEP1 HMCN2 NID1 NRG3 LTBP4	2.53e-03	261	98	6	IPR013032
Domain	Cadherin_CS	PCDHA9 DSC2 PCDHB2 PCDHA4	2.60e-03	109	98	4	IPR020894
Domain	EGF_2	VASN SVEP1 HMCN2 NID1 NRG3 LTBP4	2.73e-03	265	98	6	PS01186
Domain	CCP	IL15RA SVEP1 CSMD1	2.86e-03	54	98	3	SM00032
Domain	CADHERIN_1	PCDHA9 DSC2 PCDHB2 PCDHA4	2.97e-03	113	98	4	PS00232
Domain	Cadherin	PCDHA9 DSC2 PCDHB2 PCDHA4	2.97e-03	113	98	4	PF00028
Domain	CADHERIN_2	PCDHA9 DSC2 PCDHB2 PCDHA4	3.06e-03	114	98	4	PS50268
Domain	-	PCDHA9 DSC2 PCDHB2 PCDHA4	3.06e-03	114	98	4	2.60.40.60
Domain	SUSHI	IL15RA SVEP1 CSMD1	3.17e-03	56	98	3	PS50923
Domain	Cadherin-like	PCDHA9 DSC2 PCDHB2 PCDHA4	3.26e-03	116	98	4	IPR015919
Domain	ig	BOC NPHS1 CNTN5 PVR UNC5D	3.27e-03	190	98	5	PF00047
Domain	Immunoglobulin	BOC NPHS1 CNTN5 PVR UNC5D	3.27e-03	190	98	5	IPR013151
Domain	Sushi_SCR_CCP_dom	IL15RA SVEP1 CSMD1	3.34e-03	57	98	3	IPR000436
Domain	EGF_CA	SVEP1 HMCN2 NID1 LTBP4	3.90e-03	122	98	4	SM00179
Domain	aa-tRNA-synth_II	TARS3 TARS1	3.95e-03	18	98	2	IPR006195
Domain	AA_TRNA_LIGASE_II	TARS3 TARS1	3.95e-03	18	98	2	PS50862
Domain	EGF-like_Ca-bd_dom	SVEP1 HMCN2 NID1 LTBP4	4.14e-03	124	98	4	IPR001881
Domain	EGF	VASN SVEP1 NID1 NRG3	4.38e-03	126	98	4	PF00008
Domain	TSP_1	THSD7B SEMA5B UNC5D	4.43e-03	63	98	3	PF00090
Domain	TSP1	THSD7B SEMA5B UNC5D	4.84e-03	65	98	3	SM00209
Domain	TSP1_rpt	THSD7B SEMA5B UNC5D	4.84e-03	65	98	3	IPR000884
Domain	TSP1	THSD7B SEMA5B UNC5D	4.84e-03	65	98	3	PS50092
Domain	Cadherin_2	PCDHA9 PCDHB2 PCDHA4	4.84e-03	65	98	3	PF08266
Domain	Cadherin_N	PCDHA9 PCDHB2 PCDHA4	4.84e-03	65	98	3	IPR013164
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MTA2 SZT2 SHISA5 FBXL12 PLXND1 EDC4 RYR1 HIVEP3 MST1R SBF1 MTHFR SAC3D1 SIPA1L2 LTBP4 ATP2A3 AHNAK2	1.87e-07	1105	104	16	35748872
Pubmed	High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.	FAM120B DSC2 DTL ENKD1 SHKBP1 FREM2 PVR NID1	4.16e-06	307	104	8	37499664
Pubmed	Loss of threonyl-tRNA synthetase-like protein Tarsl2 has little impact on protein synthesis but affects mouse development.	TARS3 TARS1	8.86e-06	2	104	2	37059185
Pubmed	A threonyl-tRNA synthetase-like protein has tRNA aminoacylation and editing activities.	TARS3 TARS1	8.86e-06	2	104	2	29579307
Pubmed	Normal Weight Obese syndrome: role of single nucleotide polymorphism of IL-1 5Ralpha and MTHFR 677C-->T genes in the relationship between body composition and resting metabolic rate.	IL15RA MTHFR	8.86e-06	2	104	2	17121316
Pubmed	Mutation spectrum of genes associated with steroid-resistant nephrotic syndrome in Chinese children.	NPHS1 PLCE1	8.86e-06	2	104	2	28476686
Pubmed	Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	8.86e-06	2	104	2	15388857
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	GPHN DSC2 DTL ANKRD26 EDC4 ARHGEF17 ENKD1 ITPKB SHKBP1 SBF1 SIPA1L2 AHNAK2	1.06e-05	861	104	12	36931259
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	PLXND1 SEMA5B UNC5D PLXNB1	1.83e-05	52	104	4	26633812
Pubmed	Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.	GTF2IRD2B GTF2IRD2	2.65e-05	3	104	2	15100712
Pubmed	Targeted gene panel for genetic testing of south Indian children with steroid resistant nephrotic syndrome.	NPHS1 PLCE1	2.65e-05	3	104	2	30458709
Pubmed	PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.	PLXND1 SEMA5B PVR IGSF9 PLXNB1	2.79e-05	117	104	5	17145500
Pubmed	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	PIK3AP1 SBF1 PROX2 CSMD1 NRG3 USH2A	3.10e-05	199	104	6	23382691
Pubmed	Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population.	SHISA5 MST1R MTHFR PLXNB1	3.68e-05	62	104	4	19367581
Pubmed	Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.	BOC PLXND1 SEMA5B ROBO1 UNC5D	3.98e-05	126	104	5	16284245
Pubmed	TFII-I gene family during tooth development: candidate genes for tooth anomalies in Williams syndrome.	GTF2IRD2B GTF2IRD2	5.29e-05	4	104	2	17823943
Pubmed	Evolution of general transcription factors.	GTF2IRD2B GTF2IRD2	5.29e-05	4	104	2	23229069
Pubmed	GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members.	GTF2IRD2B GTF2IRD2	5.29e-05	4	104	2	22899722
Pubmed	Targeting skeletal endothelium to ameliorate bone loss.	HIVEP3 ROBO1	5.29e-05	4	104	2	29785024
Pubmed	Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions.	GTF2IRD2B GTF2IRD2	5.29e-05	4	104	2	21328569
Pubmed	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	NPHS1 IL10RB IL15RA RYR1 LTBP4	7.26e-05	143	104	5	20424473
Pubmed	Genetic link between renal birth defects and congenital heart disease.	PLXND1 FREM2 ROBO1	8.06e-05	28	104	3	27002738
Pubmed	Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.	SEMA5B ROBO1 PLXNB1	8.06e-05	28	104	3	18617019
Pubmed	Interplay between scatter factor receptors and B plexins controls invasive growth.	MST1R PLXNB1	8.80e-05	5	104	2	15184888
Pubmed	Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa.	FREM2 NID1	8.80e-05	5	104	2	17596926
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RTEL1 PPFIA4 ANKRD26 GALNT16 SCAF4 HIVEP3 ZNF526 RHOBTB1	1.21e-04	493	104	8	15368895
Pubmed	Genome-wide association study of lung function decline in adults with and without asthma.	SVEP1 KANK1 CSMD1	1.21e-04	32	104	3	22424883
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	DSC2 VASN PLXND1 FREM2 PVR PLXNB1	1.27e-04	257	104	6	16335952
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	MTA2 DSC2 ENKD1 ZNF526 HMCN2 MTHFR CSMD1 SIPA1L2 TOPORS LTBP4 AGBL1 UNC5D	1.29e-04	1116	104	12	31753913
Pubmed	Podocyte-Specific Deletion of Murine CXADR Does Not Impair Podocyte Development, Function or Stress Response.	NPHS1 NID1	1.32e-04	6	104	2	26076477
Pubmed	Genome-wide association study does not reveal major genetic determinants for anti-cytomegalovirus antibody response.	FREM2 AGBL1	1.32e-04	6	104	2	21993531
Pubmed	A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes.	NPHS1 NID1	1.84e-04	7	104	2	27430022
Pubmed	Analysis of polymorphism in renin angiotensin system and other related genes in South Indian chronic kidney disease patients.	NPHS1 MTHFR	1.84e-04	7	104	2	19520069
Pubmed	Tsukushi is essential for the development of the inner ear.	TSKU CLDN11	1.84e-04	7	104	2	32127020
Pubmed	Genotype-phenotype correlations in non-Finnish congenital nephrotic syndrome.	NPHS1 PLCE1	2.45e-04	8	104	2	20507940
Pubmed	RIPOR2-mediated autophagy dysfunction is critical for aminoglycoside-induced hearing loss.	GRXCR2 PINK1	2.45e-04	8	104	2	36113482
Pubmed	Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.	RYR1 ATP2A3	2.45e-04	8	104	2	19033399
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	MTA2 VASN HSPBP1 PLXND1 TSKU MST1R PVR GM2A ROBO1 NID1 ATP2A3 PLXNB1	2.53e-04	1201	104	12	35696571
Pubmed	Elongation factor 1 alpha1 and genes associated with Usher syndromes are downstream targets of GBX2.	ROBO1 USH2A	3.14e-04	9	104	2	23144817
Pubmed	A micropeptide encoded by a putative long noncoding RNA regulates muscle performance.	RYR1 ATP2A3	3.14e-04	9	104	2	25640239
Pubmed	Genetic Steroid-Resistant Nephrotic Syndrome Overview	NPHS1 PLCE1	3.14e-04	9	104	2	34436835
Pubmed	TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.	PLXND1 SEMA5B PLXNB1	3.83e-04	47	104	3	35462405
Pubmed	Activin A Determines Steroid Levels and Composition in the Fetal Testis.	CLDN11 PVR NID1	3.83e-04	47	104	3	32274496
Pubmed	Comparative mapping in the beige-satin region of mouse chromosome 13.	ITPKB NID1	3.92e-04	10	104	2	9027500
Pubmed	Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure.	NPHS1 NID1	3.92e-04	10	104	2	22840396
Pubmed	Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.	SEMA5B PLCE1	4.79e-04	11	104	2	21642993
Pubmed	SVEP1 is an endogenous ligand for the orphan receptor PEAR1.	SVEP1 NID1	4.79e-04	11	104	2	36792666
Pubmed	Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex.	PCDHA9 PCDHA4	4.79e-04	11	104	2	9655502
Pubmed	Proteins of the CNR family are multiple receptors for Reelin.	PCDHA9 PCDHA4	5.73e-04	12	104	2	10612399
Pubmed	Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.	PLXND1 PLXNB1	5.73e-04	12	104	2	21270798
Pubmed	Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.	PCDHA9 PCDHB2 PCDHA4	6.76e-04	57	104	3	32633719
Pubmed	Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.	PLXND1 PLXNB1	6.76e-04	13	104	2	10520995
Pubmed	The transcription factor Sry-related HMG box-4 (SOX4) is required for normal renal development in vivo.	NPHS1 NID1	6.76e-04	13	104	2	23559562
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	MTA2 GPHN NUP50 DTL FBXL12 HSPBP1 SHKBP1 SBF1 NID1 SIPA1L2	6.89e-04	974	104	10	28675297
Pubmed	CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.	PCDHA9 PCDHB2 PCDHA4	7.11e-04	58	104	3	30377227
Pubmed	VHL negatively regulates SARS coronavirus replication by modulating nsp16 ubiquitination and stability.	TARS3 UBASH3B	7.87e-04	14	104	2	25732088
Pubmed	The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier.	NPHS1 NID1	9.07e-04	15	104	2	28536193
Pubmed	Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.	PCDHA9 PCDHA4	9.07e-04	15	104	2	15640798
Pubmed	Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.	FREM2 NID1	1.03e-03	16	104	2	15878328
Pubmed	Tissue distribution and subcellular localization of the family of Kidney Ankyrin Repeat Domain (KANK) proteins.	KANK1 NID1	1.03e-03	16	104	2	33253712
Pubmed	Long-Range Guidance of Spinal Commissural Axons by Netrin1 and Sonic Hedgehog from Midline Floor Plate Cells.	BOC ROBO1	1.03e-03	16	104	2	30661738
Pubmed	Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.	PCDHA9 PCDHB2 PCDHA4	1.13e-03	68	104	3	11230163
Pubmed	Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.	PLXND1 PLXNB1	1.17e-03	17	104	2	11683995
Pubmed	Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.	PCDHA9 PCDHA4	1.17e-03	17	104	2	29911975
Pubmed	Semaphorin signaling facilitates cleft formation in the developing salivary gland.	PLXND1 PLXNB1	1.17e-03	17	104	2	17626059
Pubmed	Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus.	NPHS1 NID1	1.17e-03	17	104	2	18082680
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	GPHN ALPK3 IGSF9 SIPA1L2	1.18e-03	153	104	4	10718198
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MTA2 GPHN FAM120B PPFIA4 EDC4 ARHGEF17 ITPKB TARS3 SBF1 SIPA1L2 TARS1 DNPEP	1.18e-03	1431	104	12	37142655
Pubmed	CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.	PCDHA9 PCDHA4	1.31e-03	18	104	2	15570159
Pubmed	The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities.	MTA2 UBASH3B	1.31e-03	18	104	2	9790534
Pubmed	Genomic organization of the family of CNR cadherin genes in mice and humans.	PCDHA9 PCDHA4	1.31e-03	18	104	2	10662547
Pubmed	Development of a diagnostic genetic test for simplex and autosomal recessive retinitis pigmentosa.	USH2A CNGB1	1.31e-03	18	104	2	20591486
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	PCDHA9 PCDHB2 PCDHA4	1.33e-03	72	104	3	10380929
Pubmed	Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.	TSPOAP1 ZNF446 ENKD1 UBASH3B RNF111 DNPEP	1.35e-03	402	104	6	24722188
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	DSC2 SZT2 TSPOAP1 SVEP1 RYR1 FREM2 PVR	1.38e-03	552	104	7	10737800
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TSPOAP1 ARHGEF17 KANK1 NAV3 SIPA1L2 PLCE1	1.43e-03	407	104	6	12693553
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHA9 PCDHB2 PCDHA4	1.44e-03	74	104	3	10817752
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	BOC VASN CNTN5 IGSF9	1.45e-03	162	104	4	25826454
Pubmed	Transcriptional fates of human-specific segmental duplications in brain.	GTF2IRD2B GTF2IRD2	1.46e-03	19	104	2	30228200
Pubmed	Genome-wide association study of liver enzymes in korean children.	THSD7B ROBO1	1.46e-03	19	104	2	24124411
Pubmed	The DNA sequence and comparative analysis of human chromosome 5.	PCDHA9 PCDHA4 GRXCR2	1.50e-03	75	104	3	15372022
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHA9 PCDHB2 PCDHA4	1.62e-03	77	104	3	10835267
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	FREM2 HMCN2 NID1 LTBP4	1.62e-03	167	104	4	22159717
Pubmed	FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections.	ROBO1 UNC5D	1.62e-03	20	104	2	30392794
Pubmed	Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity.	PLXND1 SEMA5B	1.79e-03	21	104	2	36240771
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHA9 PCDHB2 PCDHA4	1.81e-03	80	104	3	10716726
Pubmed	Nonsyndromic Retinitis Pigmentosa Overview	TOPORS USH2A CNGB1	1.87e-03	81	104	3	20301590
Pubmed	Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli.	NPHS1 FREM2	2.15e-03	23	104	2	18787044
Pubmed	Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.	PCDHA9 PCDHA4	2.34e-03	24	104	2	24698270
Pubmed	Ubiquitin ligase MARCH5 localizes to peroxisomes to regulate pexophagy.	MTA2 CYB5R1	2.54e-03	25	104	2	34747980
Pubmed	Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition.	DSC2 GM2A	2.54e-03	25	104	2	17130451
Pubmed	Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.	PCDHA9 PCDHA4 THSD7B ITPKB	2.74e-03	193	104	4	22589738
Pubmed	Semaphorin heterodimerization in cis regulates membrane targeting and neocortical wiring.	PLXND1 ROBO1	2.75e-03	26	104	2	39152101
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	NPHS1 LILRB2 KLK14 TPRX2 HSPBP1 ZNF446 RYR1 SHKBP1 ZNF526 PVR LTBP4	8.52e-05	1192	104	11	chr19q13
GeneFamily	Fibronectin type III domain containing	BOC NPHS1 TSPOAP1 CNTN5 ROBO1 IGSF9 USH2A	3.72e-06	160	73	7	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	BOC HMCN2 CNTN5 ALPK3 ROBO1 IGSF9 UNC5D	3.88e-06	161	73	7	593
GeneFamily	Immunoglobulin like domain containing	BOC NPHS1 HMCN2 CNTN5 PVR ALPK3 IGSF9	1.27e-05	193	73	7	594
GeneFamily	Plexins	PLXND1 PLXNB1	5.68e-04	9	73	2	683
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	IL15RA SVEP1 CSMD1	1.58e-03	57	73	3	1179
GeneFamily	Clustered protocadherins	PCDHA9 PCDHB2 PCDHA4	2.21e-03	64	73	3	20
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BOC VASN SVEP1 TSKU CLDN11 NAV3 NID1 LTBP4	1.95e-08	199	102	8	f835e7ffe976843b0edbf695762d463da85793f3
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BOC VASN SVEP1 TSKU CLDN11 NAV3 NID1 LTBP4	1.95e-08	199	102	8	993fa050a095017135a6e723c77cd38b9d782e58
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	THSD7B RYR1 CNTN5 NAV3 CSMD1 USH2A AGBL1	8.40e-08	159	102	7	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 NAV3 ROBO1 CSMD1 USH2A UNC5D PLCE1	2.27e-07	184	102	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 NAV3 ROBO1 CSMD1 USH2A UNC5D PLCE1	2.27e-07	184	102	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 NAV3 ROBO1 CSMD1 USH2A UNC5D PLCE1	2.27e-07	184	102	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3AP1 EVC FREM2 KANK1 IGSF9 UBASH3B UNC5D	2.44e-07	186	102	7	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VASN GALNT16 KANK1 SEMA5B CSMD1 UNC5D PLCE1	2.72e-07	189	102	7	975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF17 GALNT16 KANK1 SEMA5B CSMD1 UNC5D PLCE1	2.82e-07	190	102	7	73d94fbae92029745989a8712eed8b99fd84c193
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DSC2 PPFIA4 THSD7B GALNT16 HMCN2 CSMD1 AGBL1	3.36e-07	195	102	7	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DSC2 PPFIA4 THSD7B GALNT16 HMCN2 CSMD1 AGBL1	3.36e-07	195	102	7	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte\|LPS_only / Treatment groups by lineage, cell group, cell type	VASN ARHGEF17 GALNT16 KANK1 NID1 CSMD1 PLCE1	3.99e-07	200	102	7	8c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCell	Posterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PCDHA4 HMCN2 PROX2 NID1 VWA3B ATP2A3	6.94e-07	135	102	6	e908aacb72a8c340f06cf5b4a6b70c2faac4d027
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EDC4 BFSP1 GTF2IRD2B VWA3B LTBP4 CNGB1	9.72e-07	143	102	6	8f897278f9ccc82ae35e4f30c5f930b2a3eb509d
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF17 GALNT16 SEMA5B CSMD1 UNC5D PLCE1	1.10e-06	146	102	6	2ac9b487a7991fdc15444aeb93533030e09825bb
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GALNT16 FREM2 KANK1 SEMA5B CSMD1 UNC5D	2.75e-06	171	102	6	4ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BOC EVC CNTN5 IGSF9 UBASH3B UNC5D	3.25e-06	176	102	6	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	THSD7B SVEP1 KANK1 HMCN2 ROBO1 PLCE1	3.46e-06	178	102	6	3c973aac16988e88f5677d3d695dd772ccfd6570
ToppCell	facs-Heart-RV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF17 FREM2 KANK1 SEMA5B PLXNB1 PLCE1	3.69e-06	180	102	6	0059e5acade6c895fd629767bea1c15f40b0d1b0
ToppCell	facs-Heart-RV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF17 FREM2 KANK1 SEMA5B PLXNB1 PLCE1	3.69e-06	180	102	6	dfb8412e1e06fa7349e66eea2ef27d9ea98b7893
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BOC PIK3AP1 EVC IGSF9 UBASH3B UNC5D	3.94e-06	182	102	6	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BOC DTL PLXND1 SEMA5B NAV3 SIPA1L2	4.19e-06	184	102	6	688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	THSD7B HMCN2 ALPK3 ROBO1 UNC5D PLCE1	4.19e-06	184	102	6	7d41784eac0935e77d6bc701f20c693adf998730
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 SEMA5B ROBO1 NRG3 SIPA1L2 PLCE1	4.33e-06	185	102	6	34fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 SEMA5B ROBO1 NRG3 SIPA1L2 PLCE1	4.33e-06	185	102	6	8816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GALNT16 KANK1 SEMA5B CSMD1 UNC5D PLCE1	4.46e-06	186	102	6	a95744b8649096bd7cfc3591a02841fa411085b3
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	THSD7B SVEP1 KANK1 ROBO1 UBASH3B PLCE1	4.74e-06	188	102	6	c66fccdfe68760b8c3efca77e3c25966dc9a8a5f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 SEMA5B ROBO1 NRG3 SIPA1L2 PLCE1	4.74e-06	188	102	6	b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BOC SVEP1 HMCN2 ROBO1 NID1 LTBP4	4.74e-06	188	102	6	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 SEMA5B ROBO1 NRG3 SIPA1L2 PLCE1	4.74e-06	188	102	6	874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BOC PIK3AP1 EVC KANK1 UBASH3B UNC5D	4.89e-06	189	102	6	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BOC VASN GALNT16 SVEP1 NID1 LTBP4	4.89e-06	189	102	6	d531399749409d614adca13d181830c6e3287508
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DSC2 EVC FREM2 CNTN5 IGSF9 UNC5D	5.04e-06	190	102	6	b855b8b7d3439023390ca44629c1a99f5d4c6801
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BOC THSD7B GALNT16 SVEP1 TSKU PLCE1	5.19e-06	191	102	6	b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCell	Basal_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	DSC2 TSKU IGSF9 LTBP4 PLXNB1 AHNAK2	5.19e-06	191	102	6	a98915bad9a4a61dd4cbca798914849b805f4a19
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SVEP1 NAV3 ROBO1 NID1 LTBP4	5.35e-06	192	102	6	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BOC SVEP1 NAV3 ROBO1 NID1 LTBP4	5.35e-06	192	102	6	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IL15RA SVEP1 HIVEP3 NAV3 ROBO1 NID1	5.51e-06	193	102	6	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DSC2 FREM2 SEMA5B CNTN5 IGSF9 UNC5D	5.68e-06	194	102	6	8ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BOC VASN SVEP1 NAV3 NID1 LTBP4	5.85e-06	195	102	6	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	Parenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	BOC PCDHA4 GALNT16 CLDN11 NAV3 LTBP4	6.20e-06	197	102	6	31c8d6e565bbdc37843ce871fe91845b0cc18a9f
ToppCell	Posterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-Kcnj8\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PCDHA4 HMCN2 PROX2 VWA3B ATP2A3	6.27e-06	113	102	5	0651fb7a7e1ea84b8365059e5ed85bf6c082da1a
ToppCell	Posterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-Kcnj8-MURAL_Mural.Acta2Rgs5.Kcnj8-Abcc9_(Mural.Acta2Rgs5.Kcnj8-Abcc9)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PCDHA4 HMCN2 PROX2 VWA3B ATP2A3	6.27e-06	113	102	5	0e153efddd061d7510dfc3859cc8b1a7984fa70e
ToppCell	COPD-Stromal-Fibroblast\|COPD / Disease state, Lineage and Cell class	BOC VASN SVEP1 NAV3 NID1 LTBP4	6.38e-06	198	102	6	7904af61473cb20064f7a3a1e1bfe8d5913cf317
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	BOC SVEP1 NAV3 ROBO1 NID1 LTBP4	6.57e-06	199	102	6	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BOC VASN SVEP1 TSKU NID1 LTBP4	6.57e-06	199	102	6	4e128c705ad36fd840582848f278770f356fcc8b
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BOC VASN SVEP1 NID1 LTBP4 AHNAK2	6.76e-06	200	102	6	933b5b400e48a511ba0a056be1d33d3610b5f10d
ToppCell	Biopsy_IPF-Mesenchymal-PLIN2+_Fibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	BOC VASN SVEP1 CLDN11 NID1 LTBP4	6.76e-06	200	102	6	2c5626ea8fb4b702d4560117e53edf6cfcf1971e
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VASN SVEP1 TSKU NID1 LTBP4 AHNAK2	6.76e-06	200	102	6	db6281b5d4032116310db379d9175d790994c99c
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BOC VASN SVEP1 NID1 LTBP4 AHNAK2	6.76e-06	200	102	6	cfea2f9d85646c9b722150551ff2e8fc4f6cc98a
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ARHGEF17 GALNT16 KANK1 SEMA5B CSMD1 PLCE1	6.76e-06	200	102	6	c06426f877919bdd267ea2fd7e7973c6619832ae
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VASN SVEP1 TSKU NID1 LTBP4 AHNAK2	6.76e-06	200	102	6	10f0c20ba7c71d9e2e177597f85b41cb40f0d878
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_adventitial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	BOC VASN GALNT16 SVEP1 NID1 LTBP4	6.76e-06	200	102	6	b04831708fa20471a127b87e8db3728b6e729ce8
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VASN SVEP1 TSKU NID1 LTBP4 AHNAK2	6.76e-06	200	102	6	a2bb67a06757f19be3f56f8cb5bb7e2affa5f4ed
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_only / Treatment groups by lineage, cell group, cell type	VASN ARHGEF17 GALNT16 KANK1 CSMD1 PLCE1	6.76e-06	200	102	6	7c62678cf408aaaf98d6df0fb27814d2007c4521
ToppCell	5'-Adult-LargeIntestine-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BOC VASN SVEP1 NID1 LTBP4 AHNAK2	6.76e-06	200	102	6	5a87bb8eb1c6bd2fbc357e1528e15ba1c0051438
ToppCell	Endothelial-Endothelial-H_(cycle)\|Endothelial / shred on cell class and cell subclass (v4)	PIK3AP1 DSC2 GALNT16 LHFPL7 SEPTIN12	1.66e-05	138	102	5	a1f41a5a9da40adcc343722baef78c603599c3f0
ToppCell	COVID-19-kidney-Technical/muscle_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	THSD7B RYR1 CNTN5 USH2A AGBL1	1.71e-05	139	102	5	64c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	THSD7B CNTN5 CSMD1 USH2A AGBL1	2.17e-05	146	102	5	c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 CSMD1 NRG3 SIPA1L2 PLCE1	2.40e-05	149	102	5	cc6224c6b79f43b97adc1ce48ca4906bff2ad318
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 CSMD1 NRG3 SIPA1L2 PLCE1	2.40e-05	149	102	5	24a7538b54b2a5291503c7493fefed4e45e8d710
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	THSD7B RYR1 CNTN5 USH2A AGBL1	2.47e-05	150	102	5	0205318a870e091add66ee4305747dda9f51510d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 ROBO1 NRG3 SIPA1L2 PLCE1	2.98e-05	156	102	5	dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 ROBO1 NRG3 SIPA1L2 PLCE1	2.98e-05	156	102	5	abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 PCDHB2 NRG3 SIPA1L2 PLCE1	3.17e-05	158	102	5	e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 PCDHB2 NRG3 SIPA1L2 PLCE1	3.17e-05	158	102	5	d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	BOC DTL PLXND1 IGSF9 UNC5D	3.17e-05	158	102	5	c8af8964a140acb2987e3b4906d72c546108d229
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GALNT16 CLDN11 KANK1 HMCN2 AHNAK2	3.37e-05	160	102	5	8624f101828efd32cdd38a65df8d94d690720a63
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GALNT16 CLDN11 KANK1 HMCN2 AHNAK2	3.37e-05	160	102	5	9de3dd6b9d4b51314d60b3b01f4132bcfa2dfc18
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RYR1 ALPK3 GM2A IGSF9 UBASH3B	3.47e-05	161	102	5	76c993a4533362db2250c88b3ee3ede55362d54e
ToppCell	droplet-Heart-nan-24m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXND1 KANK1 KANSL2 LTBP4 PINK1	3.47e-05	161	102	5	eb546d5065ac506405d240f9a1f55f2122d0c368
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPFIA4 ARHGEF17 MTHFR CSMD1 PLCE1	3.58e-05	162	102	5	c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPFIA4 ARHGEF17 MTHFR CSMD1 PLCE1	3.58e-05	162	102	5	f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPFIA4 ARHGEF17 MTHFR CSMD1 PLCE1	3.58e-05	162	102	5	5d902bb31e691aea9749617cc88303c2448f24b8
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	THSD7B RYR1 CNTN5 USH2A AGBL1	3.68e-05	163	102	5	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	BOC DTL PLXND1 PROX2 UNC5D	3.68e-05	163	102	5	1e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	BOC DTL PLXND1 PROX2 UNC5D	3.68e-05	163	102	5	431221a41d396b09170476179590eaf8a55266d8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PPFIA4 PLXND1 ARHGEF17 SEMA5B ROBO1	3.79e-05	164	102	5	b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCell	facs-Kidney-nan-24m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPHS1 PRAMEF12 SVEP1 ALPK3 ROBO1	3.90e-05	165	102	5	4cdd80580d5638fd649280ba3893251c2f898f3f
ToppCell	facs-Kidney-nan-24m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPHS1 PRAMEF12 SVEP1 ALPK3 ROBO1	3.90e-05	165	102	5	c746bb22ef52d7f7fa6ee9c37ae6bbe0ccce718e
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6\|TCGA-Liver / Sample_Type by Project: Shred V9	BOC GALNT16 SVEP1 ITPKB ATP2A3	4.37e-05	169	102	5	e992530776cab922d0360b275fb9cb8bd0017b06
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PLXND1 RYR1 GM2A NID1 CSMD1	4.37e-05	169	102	5	e3100eb587005e160bd0b7990fa57ec49765133d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPFIA4 ARHGEF17 CNTN5 ROBO1 CSMD1	4.50e-05	170	102	5	99dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPFIA4 ARHGEF17 CNTN5 ROBO1 CSMD1	4.50e-05	170	102	5	3a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPFIA4 ARHGEF17 CNTN5 ROBO1 CSMD1	4.50e-05	170	102	5	cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell	facs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPFIA4 RYR1 GM2A IGSF9 UBASH3B	5.02e-05	174	102	5	6688424fc4e40c3c4a89669a2bc79369a726f1e6
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FREM2 KANK1 LTBP4 AHNAK2 PLCE1	5.02e-05	174	102	5	a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BOC ARHGEF17 GALNT16 HMCN2 NID1	5.45e-05	177	102	5	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-Granular_Neuron_CB_Gabra6\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BOC DSC2 PCDHA4 ENKD1 IGSF9	5.45e-05	177	102	5	9b02fd91c110b405eba6cb74ceb90b1286535973
ToppCell	facs-Lung-EPCAM-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA4 RYR1 GM2A IGSF9 UBASH3B	5.60e-05	178	102	5	8c5e9fab7b55a654ccaabf2c4d02397399d94616
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MST1R FREM2 LTBP4 AHNAK2 PLCE1	5.60e-05	178	102	5	bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MST1R FREM2 LTBP4 AHNAK2 PLCE1	5.60e-05	178	102	5	c413861148129be1ee94f2ceb5999840217eebe5
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP3 UBASH3B NRG3 SIPA1L2 UNC5D	5.60e-05	178	102	5	a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PLXND1 RHOBTB1 CNTN5 CNGB1 UNC5D	5.60e-05	178	102	5	0e1bedf991189d0ef9b40dac9281bdf4739333a1
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCDHA9 VASN PCDHA4 ARHGEF17 NID1	5.75e-05	179	102	5	dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCell	facs-Marrow-B-cells-3m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLDN11 KANK1 SEMA5B NAV3 PLXNB1	5.90e-05	180	102	5	c54af6fb11484dacd3efa1f10a487376ff820a5e
ToppCell	facs-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VASN SVEP1 NAV3 GM2A AGBL1	5.90e-05	180	102	5	12537d8a569faa69f474284d2c201475722b8ca1
ToppCell	facs-Marrow-B-cells-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLDN11 KANK1 SEMA5B NAV3 PLXNB1	5.90e-05	180	102	5	07ac979b21be2425294d9818c48b5a1e6f014c19
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	THSD7B HMCN2 ALPK3 ROBO1 PLCE1	6.06e-05	181	102	5	af92b8b7f455210dab502ef6964f3a0162180759
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BOC PIK3AP1 EVC UBASH3B UNC5D	6.06e-05	181	102	5	6a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
Drug	Folic acid [59-30-3]; Up 200; 9uM; MCF7; HT_HG-U133A	MTA2 DSC2 ARHGEF17 GM2A LTBP4 ATP2A3 AHNAK2 DNPEP	2.87e-06	196	102	8	2783_UP
Drug	SR-95639A [115767-94-7]; Up 200; 10uM; MCF7; HT_HG-U133A	SZT2 RTEL1 ARHGEF17 ZNF446 MTHFR NID1 LTBP4 ATP2A3	3.10e-06	198	102	8	4977_UP
Drug	Karakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A	SZT2 RTEL1 HIVEP3 MTHFR PVR GM2A LTBP4	2.73e-05	194	102	7	4763_DN
Drug	Tropicamide [1508-75-4]; Down 200; 14uM; MCF7; HT_HG-U133A	MTA2 DSC2 ITPKB PVR GM2A ATP2A3 DNPEP	2.73e-05	194	102	7	3619_DN
Drug	Ceforanide [60925-61-3]; Up 200; 7.6uM; MCF7; HT_HG-U133A	MTA2 PCDHA9 SVEP1 RYR1 CLDN11 MTHFR GM2A	2.82e-05	195	102	7	3309_UP
Drug	D-cycloserine [68-41-7]; Up 200; 39.2uM; MCF7; HT_HG-U133A	PCDHA9 RTEL1 PLXND1 RYR1 ITPKB CNTN5 PVR	2.91e-05	196	102	7	6782_UP
Drug	chlorpromazine hydrochloride; Down 200; 1uM; MCF7; HT_HG-U133A	PCDHA9 RTEL1 ARHGEF17 SBF1 PVR LTBP4 ATP2A3	2.91e-05	196	102	7	5577_DN
Drug	Bergenin monohydrate [477-90-7]; Up 200; 11.6uM; MCF7; HT_HG-U133A	DSC2 RTEL1 RYR1 SBF1 PVR GM2A ATP2A3	3.01e-05	197	102	7	3467_UP
Drug	Piroxicam [36322-90-4]; Up 200; 12uM; MCF7; HT_HG-U133A	PCDHA9 SZT2 RTEL1 BFSP1 HIVEP3 PVR GM2A	3.21e-05	199	102	7	7445_UP
Drug	Eucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A	LILRB2 ARHGEF17 SVEP1 RYR1 MTHFR AHNAK2 PLCE1	3.32e-05	200	102	7	3935_UP
Disease	NEPHROTIC SYNDROME, TYPE 3	NPHS1 PLCE1	1.16e-05	2	101	2	C1853124
Disease	mean arterial pressure	SZT2 THSD7B SVEP1 HIVEP3 MTHFR PROX2 ROBO1 UBASH3B PLCE1	5.55e-05	499	101	9	EFO_0006340
Disease	amino acid metabolic disorder (implicated_via_orthology)	TARS3 TARS1	6.93e-05	4	101	2	DOID:9252 (implicated_via_orthology)
Disease	hypertension, pregnancy-induced	MTHFR PLCE1	1.15e-04	5	101	2	MONDO_0024664
Disease	metastasis measurement, disease progression measurement	PIK3AP1 CECR9 CNTN5	2.16e-04	34	101	3	EFO_0007675, EFO_0008336
Disease	glucagon-like peptide-1 measurement	CSMD1 AGBL1	5.13e-04	10	101	2	EFO_0008465
Disease	Osteosarcoma	GRM4 MST1R TOPORS	5.66e-04	47	101	3	C0029463
Disease	gastric adenocarcinoma (is_implicated_in)	RTEL1 PLCE1	6.25e-04	11	101	2	DOID:3717 (is_implicated_in)
Disease	Hyperhomocysteinemia	NPHS1 MTHFR	6.25e-04	11	101	2	C0598608
Disease	response to virus	FREM2 AGBL1	6.25e-04	11	101	2	GO_0009615
Disease	Disorder of eye	PDE6H FREM2 TOPORS USH2A CNGB1	8.27e-04	212	101	5	C0015397
Disease	FEV/FEC ratio	BOC BMF ARHGEF17 HIVEP3 FREM2 KANK1 CNTN5 GM2A UBASH3B CSMD1 LTBP4 ATP2A3	1.00e-03	1228	101	12	EFO_0004713
Disease	preeclampsia, hypertension, pregnancy-induced	MTHFR PLCE1	1.35e-03	16	101	2	EFO_0000668, MONDO_0024664
Disease	lymphocyte count	PIK3AP1 BMF PLXND1 SBK1 MST1R GTF2IRD2B KANSL2 CNTN5 PVR GTF2IRD2 UBASH3B PLCE1 DNPEP	1.47e-03	1464	101	13	EFO_0004587
Disease	graft-versus-host disease (is_implicated_in)	IL10RB MTHFR	1.53e-03	17	101	2	DOID:0081267 (is_implicated_in)
Disease	interstitial lung disease	THSD7B CSMD1 NRG3	1.59e-03	67	101	3	EFO_0004244
Disease	Retinitis pigmentosa	TOPORS USH2A CNGB1	2.12e-03	74	101	3	cv:C0035334
Disease	respiratory symptom measurement, COVID-19	FREM2 CSMD1 UNC5D	2.12e-03	74	101	3	EFO_0007939, MONDO_0100096
Disease	heart failure, diabetes mellitus, stroke, atrial fibrillation, mortality, coronary artery disease, cancer	ANKRD26 SEMA5B	2.12e-03	20	101	2	EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004352, MONDO_0004992
Disease	glomerular filtration rate, renal transplant outcome measurement, donor genotype effect measurement	BFSP1 CSMD1	2.56e-03	22	101	2	EFO_0005199, EFO_0005208, EFO_0007892
Disease	diet measurement, fasting blood insulin measurement	NRG3 AGBL1	2.56e-03	22	101	2	EFO_0004466, EFO_0008111
Disease	Renal glomerular disease	NPHS1 PLCE1	2.80e-03	23	101	2	C0268731
Disease	Glomerulopathy Assessment	NPHS1 PLCE1	2.80e-03	23	101	2	C4521256
Disease	gestational diabetes	IL15RA LTBP4	2.80e-03	23	101	2	EFO_0004593
Disease	diet measurement, HOMA-IR	NRG3 AGBL1	2.80e-03	23	101	2	EFO_0004501, EFO_0008111
Disease	osteonecrosis	EVC HIVEP3	3.31e-03	25	101	2	EFO_0004259

Protein segments in the cluster

Peptide	Gene	Start	Entry
MCEGPSRISGPIPPD	ENKD1	1	Q9H0I2
MPTLVVGTPPTCLGD	CCDC187	1	A0A096LP49
GVALVSDMCPDPGIP	CSMD1	341	Q96PZ7
MVRNDTPCGTTIGPI	DNPEP	416	Q9ULA0
RVGLCPRMDPVDGTQ	GRM4	431	Q14833
GCPLAGLSQEVPTMP	ALPK3	1056	Q96L96
LPLPLRPCGEGSEMV	DTL	636	Q9NZJ0
LTTRPVMEPPCVGNL	ANKRD26	1601	Q9UPS8
GPPQVDGTPTMSLER	PIK3AP1	761	Q6ZUJ8
DEGPECNPPIQTVRM	DSC2	466	Q02487
LTFVGCVGMLDPPRP	ATP2A3	591	Q93084
PPTTQPMLERKCGVQ	AGBL1	541	Q96MI9
LGGNPCPLVTITAMP	AGBL1	766	Q96MI9
GTAVMVTCPNRPLVP	CECR9	36	P0C854
SVREGQGVVLMCSPP	CNTN5	206	O94779
SPGSPVILQMCNPRE	GALNT16	496	Q8N428
LNVLIPPNMPCTRTG	NUP50	406	Q9UKX7
TLVPQGGPVLCRDEM	MTA2	251	O94776
MPTEGECAPGKPTLV	PCDHA9	726	Q9Y5H5
MEQLTTLPRPGDPGA	TSPOAP1	1	O95153
VPPCVSRSLEPMAGQ	EDC4	1051	Q6P2E9
NVTPLGMLSRPVCGI	GPHN	121	Q9NQX3
RCSVPEGPFPGQMVD	PCDHB2	726	Q9Y5E7
CVPGPQEGLRPMSDS	ARHGEF17	351	Q96PE2
IPSVGLEETCLQMPG	NRG3	601	P56975
CQVGRSEMGPELVSP	NPHS1	111	O60500
MGITCPIVPGIFPIQ	MTHFR	246	P42898
PRDCMVPVVFPGPVS	MAD2L1BP	51	Q15013
PATRGITCPPPMSVE	IL15RA	26	Q13261
GSGEVPRPQMCSPKL	GRXCR2	66	A6NFK2
PRTITPGMVCAGVPQ	KLK14	196	Q9P0G3
GELVTMVCPVRGSPP	HMCN2	3336	Q8NDA2
TLCGSSGPLPVPEMI	PPFIA4	576	O75335
PELGSGCPLRMVVQE	FREM2	701	Q5SZK8
GPVLDSRDCLPPVMP	PLXNB1	71	O43157
GCLMAPEVSTARPGP	PINK1	411	Q9BXM7
GPSRCPAMTVLPSEI	PLXND1	596	Q9Y4D7
MPEGALPAPVPVCVR	PLXND1	1036	Q9Y4D7
VEGTRTRPGMTPPCL	NID1	906	P14543
VTIGPRLFLPCPMDV	NAV3	2236	Q8IVL0
MRTIACGPPQLTVGL	KANK1	776	Q14678
PGPVMAPGESLTLQC	LILRB2	231	Q8N423
PSGPPMTAILERCSG	SBF1	541	O95248
IVRGMCLSPNPLVPG	PROX2	71	Q3B8N5
PRVCSGEGPPKTDLM	PCDHA4	756	Q9UN74
CPRPGGQQPLMVILD	PRAMEF12	136	O95522
SECPEMPLPLIPGER	GRID2IP	521	A4D2P6
GTVILGCVVEPPRMN	BOC	51	Q9BWV1
RPCAMVTPGAEEPSI	BFSP1	571	Q12934
TVLPCIRMGQEPGVA	CLDN11	101	O75508
GVMLPCGVTEEPQRL	BMF	81	Q96LC9
CPVDDTIIGPPGMQV	IL10RB	106	Q08334
SPEEFDPMTGRCVPP	LTBP4	1121	Q8N2S1
LDVVGDGMQCPPSPL	KANSL2	411	Q9H9L4
QTLPGMTGLPPEECD	EVC	541	P57679
ITFNPGCVVIDGMPP	GTF2IRD2	361	Q86UP8
ITFNPGCVVIDGMPP	GTF2IRD2B	361	Q6EKJ0
GLCPRRSSVPMPGVQ	LHFPL7	96	Q6ICI0
FGPIESINMIPPRGC	SCAF4	531	O95104
SPRSPLMPGCELPVG	SAC3D1	41	A6NKF1
MSVGCPEPEPPRSLT	SBK1	1	Q52WX2
GLPNSVEEMCPDIPV	RYR1	3231	P21817
LSPEPQPMGVRVICG	PIP4P1	161	Q86T03
DPEPRQEVPMCTGPE	FAM120B	406	Q96EK7
NTPVALPRCSEMVPG	FUT5	86	Q11128
CLRVLSQPMPPTAGE	HSPBP1	96	Q9NZL4
LTGEPVPMARCVSTG	PVR	156	P15151
TCTDLTGRPYPGMEP	RTEL1	1131	Q9NZ71
DMLIPTGEPCPEPLR	GM2A	116	P17900
SPRQVMVIPVGPTCE	TARS3	696	A2RTX5
LSPRQVMVVPVGPTC	TARS1	616	P26639
CMVLRLGFPIGTPAP	SZT2	661	Q5T011
CDGEPQGMLPPEVVI	USH2A	3016	O75445
PPCPRLNGVLMEVEE	NBPF10	3711	Q6P3W6
PLLPCGRVMEPPSTV	PLCE1	371	Q9P212
IPASPRCGSPTAMEI	ITPKB	261	P27987
SLCLQGPLVTPEMPS	FBXL12	256	Q9NXK8
GIDTAPCMPATILGP	SIPA1L2	1266	Q9P2F8
PSGQPEEPGMVRLVC	SHKBP1	186	Q8TBC3
TPPPGARGEVCMASR	SHISA5	21	Q8N114
PVIKIPECPSMGTNE	RHOBTB1	241	O94844
DDVLVLLCGPPPMVQ	CYB5R1	271	Q9UHQ9
CIPVRCGEPPSIMNG	SVEP1	2141	Q4LDE5
PVMSPLSPGERVQCP	AHNAK2	4891	Q8IVF2
PGMEGLGTDITVICP	PDE6H	51	Q13956
CMSPGPEPGEQILSV	CNGB1	1226	Q14028
PPVVPLVLGDMICAT	PRSS45P	161	Q7RTY3
VTETGPPAMPRLPSC	RNF111	466	Q6ZNA4
TPPCEMLGPVGIEAV	SEPTIN12	21	Q8IYM1
PCPLIPIGGIQMVQA	HIVEP3	2191	Q5T1R4
SVPMPVVGILGEPRC	PPP1R36	356	Q96LQ0
VAVGEPAVMECQPPR	ROBO1	181	Q9Y6N7
CLPPGARTAEGPIMV	SEMA5B	46	Q9P283
ETPLPIGMPGVIRCP	IGSF9	331	Q9P2J2
EVLLSPEVTCGPPDM	UNC5D	596	Q6UXZ4
PEVTCGPPDMIVTTP	UNC5D	601	Q6UXZ4
YSVCVMPLGPGRVPE	VASN	531	Q6EMK4
GPPCLPVMDPETTLE	ZNF446	6	Q9NWS9
GPTCTGPMREGPRAV	nan	41	Q5W150
MGSQPPLGSPLSREE	TOPORS	1	Q9NS56
PPEPQQTIMCTELGE	ZNF526	616	Q8TF50
GSDPGLMCPSLTPEL	PLEKHG7	576	Q6ZR37
GLGETTPLTIICQPM	UBASH3B	356	Q8TF42
ITPVGGAMPCPLLQV	VWA3B	1081	Q502W6
IMPTQGEGRPCPTEL	THSD7B	1276	Q9C0I4
RVDCSGLGPHIMPVP	TSKU	41	Q8WUA8
GDMVVCPLPPSLQLG	MST1R	911	Q04912
CPGPIPDPVLGRTLM	TPRX2	211	P0DV77
GTRPQGGEARCMIPP	nan	6	A6NHS1