Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone binding

ING5 HINFP ING2

2.59e-04265103GO:0042393
GeneOntologyMolecularFunctionmethylated histone binding

ING5 ING2

8.07e-0486102GO:0035064
GeneOntologyMolecularFunctionmethylation-dependent protein binding

ING5 ING2

8.44e-0488102GO:0140034
GeneOntologyMolecularFunctionintegrin binding

ITGA11 CASR

3.28e-03175102GO:0005178
GeneOntologyMolecularFunctionmodification-dependent protein binding

ING5 ING2

4.51e-03206102GO:0140030
GeneOntologyMolecularFunctionchromatin binding

ING5 HINFP ING2

4.98e-03739103GO:0003682
HumanPhenoParathyroid adenoma

PRDM10 CASR

2.77e-051632HP:0002897
HumanPhenoNeoplasm of the parathyroid gland

PRDM10 CASR

3.95e-051932HP:0100733
HumanPhenoAbnormal parathyroid morphology

PRDM10 CASR

5.84e-052332HP:0011766
DomainING_N_histone_binding

ING5 ING2

2.06e-06592IPR024610
DomainING_fam

ING5 ING2

2.06e-06592IPR028651
DomainING

ING5 ING2

2.06e-06592SM01408
DomainING

ING5 ING2

2.06e-06592PF12998
DomainZinc_finger_PHD-type_CS

ING5 ING2

4.23e-046592IPR019786
DomainPHD

ING5 ING2

5.62e-047592PF00628
DomainZnf_PHD-finger

ING5 ING2

6.24e-047992IPR019787
DomainPHD

ING5 ING2

7.91e-048992SM00249
DomainZnf_PHD

ING5 ING2

8.27e-049192IPR001965
DomainZF_PHD_2

ING5 ING2

9.00e-049592PS50016
DomainZF_PHD_1

ING5 ING2

9.19e-049692PS01359
DomainZnf_FYVE_PHD

ING5 ING2

2.14e-0314792IPR011011
Domain-

ING5 ING2

1.86e-02449923.30.40.10
DomainZnf_RING/FYVE/PHD

ING5 ING2

1.94e-0245992IPR013083
Domain-

PRDM10 HINFP

4.01e-02679923.30.160.60
Domainzf-C2H2

PRDM10 HINFP

4.16e-0269392PF00096
DomainZnf_C2H2/integrase_DNA-bd

PRDM10 HINFP

4.17e-0269492IPR013087
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION

ING5 ING2

4.07e-052952MM15340
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION

ING5 ING2

4.36e-053052M27637
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY

ING5 ING2

1.21e-0315752MM15226
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY

ING5 ING2

1.25e-0316052M27498
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53

ING5 ING2

4.44e-0330452MM14960
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_TP53

ING5 ING2

6.18e-0336052M27267
Pubmed

ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression.

ING5 ING2

1.56e-06710216728974
Pubmed

ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

ING5 ING2

6.37e-054210216387653
CytobandEnsembl 112 genes in cytogenetic band chr11q24

PRDM10 CCDC15

7.58e-04191102chr11q24
GeneFamilyPHD finger proteins

ING5 ING2

3.63e-04906288
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

PRDM10 HINFP

2.12e-027186228
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ING5 PRDM10 ING2

5.50e-06163103a24db9d266a40f3bffe4f18d277bc269791b4560
ToppCellParenchymal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_endoneurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PRDM10 CASR

4.56e-04145102e808502fa52baf1c400f3c9b918a167127e78af9
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA11 CASR

5.55e-041601026215ac6123a295f3c2f033786602a57b2e2e1177
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ING2 ZAN

5.90e-041651020edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ING2 ZAN

5.90e-04165102fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRDM10 CCDC15

6.26e-041701023ad9f950b87ee98f025ab9b4a8ed551e6a9b4764
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC15 DISP2

6.33e-04171102b0373ed8283ee1792b6a490bff93906546978593
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC15 DISP2

6.33e-04171102b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCelldroplet-Liver-LIVER-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC15 DISP2

6.71e-041761024880fa20b50eb10358e08567e08559ef2954f237
ToppCelldroplet-Liver-LIVER-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC15 DISP2

6.71e-04176102fcdddd949ca05b3ecde240db9e38296a6eab2d6a
ToppCelldroplet-Liver-LIVER-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC15 DISP2

6.71e-041761024d2fb51e71bed0d72f3d7f89d395744860885a5f
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ING5 ITGA11

6.86e-04178102cb9a446c145b1435cfe12a1d4568aed0924a6a20
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRDM10 HINFP

7.09e-04181102709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA11 CASR

7.48e-04186102360c3e9e5c3a943e68e6939b4a47821bfc75b553
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA11 CASR

8.14e-04194102735eee6ef25589f935fa922788ebbdbfef61249e
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA11 CASR

8.30e-041961021f47916c2663bd88c1e7c19c6a7688f4c7173ad2
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA11 CASR

8.30e-041961021bcae4e0a244af822e2b12b2026a2771316f107d
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CCDC15 CASR

8.39e-041971021ffbbe44db0fd3ebd91ad16ab0b91153de5d7c6d
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ITGA11 DISP2

8.39e-0419710231c8d6e565bbdc37843ce871fe91845b0cc18a9f
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA11 CASR

8.39e-04197102467e7cbf511d3bcc701923603032aaf0bba2736d
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA11 CASR

8.47e-04198102447d7182edb2cd8a72ebd3c0d16bc6e4ddcaaa5c
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

VPS13C PRDM10

8.56e-04199102174f6013af6eafa577f84205a62927f2b367fda3
DiseaseUterine leiomyoma

ING5 ITGA11

4.17e-0491102HP_0000131
Diseaseuterine fibroid

ING5 ITGA11

1.97e-03199102EFO_0000731
Diseasecardiac troponin T measurement

ING2 CASR

2.37e-03219102EFO_0005043
Diseasediverticular disease

ING5 DISP2

2.75e-03236102EFO_0009959
Diseasemean platelet volume

ING5 CASR ZAN

4.12e-031020103EFO_0004584
DiseaseS-6-hydroxywarfarin measurement

VPS13C ING2

6.53e-03368102EFO_0803326
Diseaseglucose measurement

VPS13C ZAN

6.95e-03380102EFO_0004468
DiseaseIGF-1 measurement

VPS13C ITGA11

1.12e-02488102EFO_0004627
Diseaseserum IgG glycosylation measurement

VPS13C ITGA11

1.28e-02523102EFO_0005193
Diseasecalcium measurement

HINFP CASR

1.82e-02628102EFO_0004838

Protein segments in the cluster

PeptideGeneStartEntry
ACNKCPDDFWSNENH

CASR

581

P41180
DLCCGHSDFPWAPQF

DISP2

856

A7MBM2
PFWNGCNEDEHCVPD

ITGA11

776

Q9UKX5
RPFDPHDLWCEECNN

PRDM10

166

Q9NQV6
IGCDNEQCPIEWFHF

ING2

226

Q9H160
GCDNPDCPIEWFHFA

ING5

201

Q8WYH8
CLWEHCENSFDNPEW

HINFP

131

Q9BQA5
DFWDAHPDTCANNCI

CCDC15

891

Q0P6D6
CVDWQCPFEDFVFPP

VPS13C

3666

Q709C8
PQCDFEDNAHPFCDW

ZAN

371

Q9Y493