Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transcription coactivator binding	GATA2 GATA3 GATA1	1.36e-04	54	37	3	GO:0001223
GeneOntologyBiologicalProcess	eosinophil fate commitment	GATA2 GATA1	3.13e-06	2	37	2	GO:0035854
GeneOntologyBiologicalProcess	regulation of primitive erythrocyte differentiation	GATA2 GATA1	9.38e-06	3	37	2	GO:0010725
GeneOntologyBiologicalProcess	embryonic hemopoiesis	GATA2 GATA3 GATA1	2.54e-05	32	37	3	GO:0035162
GeneOntologyBiologicalProcess	positive regulation of thyroid hormone generation	GATA3 CTNS	3.12e-05	5	37	2	GO:2000611
GeneOntologyBiologicalProcess	regulation of thyroid hormone generation	GATA3 CTNS	6.54e-05	7	37	2	GO:2000609
GeneOntologyBiologicalProcess	eosinophil differentiation	GATA2 GATA1	6.54e-05	7	37	2	GO:0030222
GeneOntologyBiologicalProcess	primitive erythrocyte differentiation	GATA2 GATA1	8.71e-05	8	37	2	GO:0060319
GeneOntologyBiologicalProcess	primitive hemopoiesis	GATA2 GATA1	2.04e-04	12	37	2	GO:0060215
Domain	TF_GATA-2/3	GATA2 GATA3 GATA1	6.58e-09	3	36	3	IPR016374
Domain	ZnF_GATA	GATA2 GATA3 GATA1	1.43e-06	12	36	3	SM00401
Domain	Znf_GATA	GATA2 GATA3 GATA1	2.95e-06	15	36	3	IPR000679
Domain	GATA	GATA2 GATA3 GATA1	2.95e-06	15	36	3	PF00320
Domain	GATA_ZN_FINGER_1	GATA2 GATA3 GATA1	3.62e-06	16	36	3	PS00344
Domain	GATA_ZN_FINGER_2	GATA2 GATA3 GATA1	3.62e-06	16	36	3	PS50114
Domain	-	GATA2 GATA3 GATA1	1.79e-04	57	36	3	3.30.50.10
Domain	Znf_NHR/GATA	GATA2 GATA3 GATA1	1.89e-04	58	36	3	IPR013088
Pubmed	GATA suppresses erythropoietin gene expression through GATA site in mouse erythropoietin gene promoter.	GATA2 GATA3 GATA1	1.11e-09	3	37	3	12041667
Pubmed	Dynamic regulation of Gata factor levels is more important than their identity.	GATA2 GATA3 GATA1	1.11e-09	3	37	3	17327407
Pubmed	GATA-1, -2 and -3 genes expression in bone marrow microenviroment with chronic aplastic anemia.	GATA2 GATA3 GATA1	1.11e-09	3	37	3	17654061
Pubmed	GATA-binding transcription factors in mast cells regulate the promoter of the mast cell carboxypeptidase A gene.	GATA2 GATA3 GATA1	1.11e-08	5	37	3	1744088
Pubmed	Normal reproductive and macrophage function in Pem homeobox gene-deficient mice.	GATA2 GATA3 GATA1	1.11e-08	5	37	3	9769172
Pubmed	Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells.	GATA2 GATA3 GATA1	2.21e-08	6	37	3	10364157
Pubmed	Direct protein interactions are responsible for Ikaros-GATA and Ikaros-Cdk9 cooperativeness in hematopoietic cells.	GATA2 GATA3 GATA1	2.21e-08	6	37	3	23732910
Pubmed	Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factors.	GATA2 GATA3 GATA1	3.87e-08	7	37	3	11724781
Pubmed	GATA factors and androgen receptor collaborate to transcriptionally activate the Rhox5 homeobox gene in Sertoli cells.	GATA2 GATA3 GATA1	3.87e-08	7	37	3	18212046
Pubmed	Gata6 restricts Isl1 to the posterior of nascent hindlimb buds through Isl1 cis-regulatory modules.	GATA2 GATA3 GATA1	6.18e-08	8	37	3	29197504
Pubmed	Gata6 is an important regulator of mouse pancreas development.	GATA2 GATA3 GATA1	6.15e-07	16	37	3	16887115
Pubmed	Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins.	GATA2 GATA3 GATA1	6.15e-07	16	37	3	10208738
Pubmed	Geminin deletion increases the number of fetal hematopoietic stem cells by affecting the expression of key transcription factors.	GATA2 GATA3 GATA1	8.94e-07	18	37	3	25516969
Pubmed	Prethymic T-cell development defined by the expression of paired immunoglobulin-like receptors.	GATA2 GATA3 GATA1	1.06e-06	19	37	3	16292344
Pubmed	Essential and instructive roles of GATA factors in eosinophil development.	GATA2 GATA1	1.10e-06	2	37	2	12045236
Pubmed	GATA-2 reinforces megakaryocyte development in the absence of GATA-1.	GATA2 GATA1	1.10e-06	2	37	2	19620289
Pubmed	GATA2-dependent and region-specific regulation of Gata2 transcription in the mouse midbrain.	GATA2 GATA3	1.10e-06	2	37	2	19371385
Pubmed	Overexpression of human GATA-1 and GATA-2 interferes with spine formation and produces depressive behavior in rats.	GATA2 GATA1	1.10e-06	2	37	2	25340772
Pubmed	Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis.	GATA2 GATA1	1.10e-06	2	37	2	26766440
Pubmed	Roles of hematopoietic transcription factors GATA-1 and GATA-2 in the development of red blood cell lineage.	GATA2 GATA1	1.10e-06	2	37	2	12432220
Pubmed	Context-dependent GATA factor function: combinatorial requirements for transcriptional control in hematopoietic and endothelial cells.	GATA2 GATA1	1.10e-06	2	37	2	17347142
Pubmed	GATA factor activity is required for the trophoblast-specific transcriptional regulation of the mouse placental lactogen I gene.	GATA2 GATA3	1.10e-06	2	37	2	7720565
Pubmed	Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy.	GATA2 GATA1	1.10e-06	2	37	2	19941826
Pubmed	Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease.	GATA2 GATA3	1.10e-06	2	37	2	15328158
Pubmed	[Expression of GATA-1 and GATA-2 in the bone marrow of patients with Monge's disease].	GATA2 GATA1	1.10e-06	2	37	2	18078130
Pubmed	The GATA transcriptional program dictates cell fate equilibrium to establish the maternal-fetal exchange interface and fetal development.	GATA2 GATA3	1.10e-06	2	37	2	38346193
Pubmed	GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene.	GATA2 GATA3	1.10e-06	2	37	2	16055713
Pubmed	Functional overlap of GATA-1 and GATA-2 in primitive hematopoietic development.	GATA2 GATA1	1.10e-06	2	37	2	14504093
Pubmed	Differential GATA factor stabilities: implications for chromatin occupancy by structurally similar transcription factors.	GATA2 GATA1	1.10e-06	2	37	2	18154321
Pubmed	Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis.	GATA2 GATA1	1.10e-06	2	37	2	22383799
Pubmed	GATA-1 and GATA-2 gene expression is related to the severity of dysplasia in myelodysplastic syndrome.	GATA2 GATA1	1.10e-06	2	37	2	12145700
Pubmed	Knock-in mutation of transcription factor GATA-3 into the GATA-1 locus: partial rescue of GATA-1 loss of function in erythroid cells.	GATA3 GATA1	1.10e-06	2	37	2	9576834
Pubmed	GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling.	GATA2 GATA1	1.10e-06	2	37	2	12857954
Pubmed	Decreased mRNA expression of GATA1 and GATA2 is associated with tumor aggressiveness and poor outcome in clear cell renal cell carcinoma.	GATA2 GATA1	1.10e-06	2	37	2	25230694
Pubmed	GATA factor switching from GATA2 to GATA1 contributes to erythroid differentiation.	GATA2 GATA1	1.10e-06	2	37	2	23911012
Pubmed	GATA factor mutations in hematologic disease.	GATA2 GATA1	1.10e-06	2	37	2	28179280
Pubmed	Progenitor stage-specific activity of a cis-acting double GATA motif for Gata1 gene expression.	GATA2 GATA1	1.10e-06	2	37	2	25535330
Pubmed	The essential role of GATA transcription factors in adult murine prostate.	GATA2 GATA3	1.10e-06	2	37	2	27374105
Pubmed	Selection of peptides with affinity for the N-terminal domain of GATA-1: Identification of a potential interacting protein.	GATA3 GATA1	1.10e-06	2	37	2	12767938
Pubmed	GATA3 is downregulated during hair cell differentiation in the mouse cochlea.	GATA2 GATA3	1.10e-06	2	37	2	10447238
Pubmed	Context-dependent function of regulatory elements and a switch in chromatin occupancy between GATA3 and GATA2 regulate Gata2 transcription during trophoblast differentiation.	GATA2 GATA3	1.10e-06	2	37	2	19106099
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TAOK2 ZNF512B PLCB1 FNDC3A DLG5 ZNF646 EFR3A	1.26e-06	529	37	7	14621295
Pubmed	Jak2 is essential for signaling through a variety of cytokine receptors.	GATA2 GATA3 GATA1	1.45e-06	21	37	3	9590173
Pubmed	Human transcription factor protein interaction networks.	GATA2 GATA3 ZNF512B ZFHX3 CAD HERC1 CLPX POM121C PABPC3 GATA1	1.68e-06	1429	37	10	35140242
Pubmed	GATA6 is a crucial regulator of Shh in the limb bud.	GATA2 GATA3 GATA1	2.83e-06	26	37	3	24415953
Pubmed	Repression via the GATA box is essential for tissue-specific erythropoietin gene expression.	GATA2 GATA3	3.30e-06	3	37	2	18202227
Pubmed	GATA transcription factors are involved in IgE-dependent mast cell degranulation by enhancing the expression of phospholipase C-γ1.	GATA2 GATA1	3.30e-06	3	37	2	22390417
Pubmed	Molecular cloning and characterization of the GATA1 cofactor human FOG1 and assessment of its binding to GATA1 proteins carrying D218 substitutions.	GATA2 GATA1	3.30e-06	3	37	2	12483298
Pubmed	An intron GATA-binding site regulates chromatin accessibility and is essential for IL-4 gene expression in mast cells.	GATA2 GATA1	3.30e-06	3	37	2	15739164
Pubmed	Antagonism of FOG-1 and GATA factors in fate choice for the mast cell lineage.	GATA2 GATA1	3.30e-06	3	37	2	18299398
Pubmed	Chromatin occupancy and epigenetic analysis reveal new insights into the function of the GATA1 N terminus in erythropoiesis.	GATA2 GATA1	3.30e-06	3	37	2	31409672
Pubmed	Molecular hallmarks of endogenous chromatin complexes containing master regulators of hematopoiesis.	GATA2 GATA1	3.30e-06	3	37	2	18779319
Pubmed	GATA transcription factors inhibit cytokine-dependent growth and survival of a hematopoietic cell line through the inhibition of STAT3 activity.	GATA2 GATA1	3.30e-06	3	37	2	15673499
Pubmed	GATA factors are essential for transcription of the survival gene E4bp4 and the viability response of interleukin-3 in Ba/F3 hematopoietic cells.	GATA2 GATA1	3.30e-06	3	37	2	12023274
Pubmed	The upregulation of Gata transcription factors family and FOG-1 in expanded and differentiated cord blood-derived CD34+ hematopoietic stem cells to megakaryocyte lineage during co-culture with cord blood mesenchymal stem cells.	GATA2 GATA1	3.30e-06	3	37	2	35690555
Pubmed	Exchange of GATA factors mediates transitions in looped chromatin organization at a developmentally regulated gene locus.	GATA2 GATA1	3.30e-06	3	37	2	18243117
Pubmed	HBV suppresses expression of MICA/B on hepatoma cells through up-regulation of transcription factors GATA2 and GATA3 to escape from NK cell surveillance.	GATA2 GATA3	3.30e-06	3	37	2	27528231
Pubmed	Regulation of endogenous retrovirus-derived regulatory elements by GATA2/3 and MSX2 in human trophoblast stem cells.	GATA2 GATA3	3.30e-06	3	37	2	36806146
Pubmed	Genetic redundancy of GATA factors in the extraembryonic trophoblast lineage ensures the progression of preimplantation and postimplantation mammalian development.	GATA2 GATA3	3.30e-06	3	37	2	28232602
Pubmed	GATA-1 and GATA-2 binding to 3' enhancer of WT1 gene is essential for its transcription in acute leukemia and solid tumor cell lines.	GATA2 GATA1	3.30e-06	3	37	2	19212333
Pubmed	GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis.	GATA2 GATA1	3.30e-06	3	37	2	12077323
Pubmed	Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA-1 and GATA-2.	GATA2 GATA1	3.30e-06	3	37	2	15215894
Pubmed	Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate.	GATA2 GATA1	3.30e-06	3	37	2	19491391
Pubmed	Regulation of GATA factor expression is distinct between erythroid and mast cell lineages.	GATA2 GATA1	3.30e-06	3	37	2	22988301
Pubmed	c-Jun is required for the specification of joint cell fates.	GATA2 GATA3 GATA1	4.88e-06	31	37	3	23475960
Pubmed	Transcription factor GATA1 is dispensable for mast cell differentiation in adult mice.	GATA2 GATA1	6.60e-06	4	37	2	24615013
Pubmed	The murine placenta contains hematopoietic stem cells within the vascular labyrinth region.	GATA2 GATA3	6.60e-06	4	37	2	15737933
Pubmed	Interaction between GATA and the C/EBP family of transcription factors is critical in GATA-mediated suppression of adipocyte differentiation.	GATA2 GATA3	6.60e-06	4	37	2	15632071
Pubmed	SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis.	GATA2 GATA1	6.60e-06	4	37	2	20457756
Pubmed	GATA-2 and GATA-3 regulate trophoblast-specific gene expression in vivo.	GATA2 GATA3	6.60e-06	4	37	2	9043071
Pubmed	Clinical significance of Gata-1, Gata-2, EKLF, and c-MPL expression in acute myeloid leukemia.	GATA2 GATA1	6.60e-06	4	37	2	19097174
Pubmed	Multiple, distant Gata2 enhancers specify temporally and tissue-specific patterning in the developing urogenital system.	GATA2 GATA3	6.60e-06	4	37	2	15542836
Pubmed	Notch1-mediated signaling induces MHC class II expression through activation of class II transactivator promoter III in mast cells.	GATA2 GATA1	6.60e-06	4	37	2	21321116
Pubmed	Histone modifications silence the GATA transcription factor genes in ovarian cancer.	GATA2 GATA1	6.60e-06	4	37	2	16607277
Pubmed	The transcription factor GATA3 is a downstream effector of Hoxb1 specification in rhombomere 4.	GATA2 GATA3	6.60e-06	4	37	2	10556076
Pubmed	Significance of NF-kappaB/GATA axis in tumor necrosis factor-alpha-induced expression of 6-sulfated cell recognition glycans in human T-lymphocytes.	GATA2 GATA3	6.60e-06	4	37	2	18849568
Pubmed	Critical Roles for PU.1, GATA1, and GATA2 in the expression of human FcεRI on mast cells: PU.1 and GATA1 transactivate FCER1A, and GATA2 transactivates FCER1A and MS4A2.	GATA2 GATA1	6.60e-06	4	37	2	24639354
Pubmed	Loss of LKLF function results in embryonic lethality in mice.	GATA3 GATA1	6.60e-06	4	37	2	9859212
Pubmed	Cooperative action of multiple cis-acting elements is required for N-myc expression in branchial arches: specific contribution of GATA3.	GATA3 GATA1	6.60e-06	4	37	2	20855530
Pubmed	GATA2 functions in adrenal chromaffin cells.	GATA2 GATA3	6.60e-06	4	37	2	32562431
Pubmed	A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis.	GATA2 GATA3 GATA1	9.11e-06	38	37	3	38346162
Pubmed	An intricate regulatory circuit between FLI1 and GATA1/GATA2/LDB1/ERG dictates erythroid vs. megakaryocytic differentiation.	GATA2 GATA1	1.10e-05	5	37	2	38695236
Pubmed	GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis.	GATA2 GATA3	1.10e-05	5	37	2	20705609
Pubmed	Noncoding variants alter GATA2 expression in rhombomere 4 motor neurons and cause dominant hereditary congenital facial paresis.	GATA2 GATA3	1.10e-05	5	37	2	37386251
Pubmed	UG4 enhancer-driven GATA-2 and bone morphogenetic protein 4 complementation remedies the CAKUT phenotype in Gata2 hypomorphic mutant mice.	GATA2 GATA3	1.10e-05	5	37	2	22493062
Pubmed	Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1.	GATA2 GATA1	1.10e-05	5	37	2	7568177
Pubmed	Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development.	GATA2 GATA1	1.10e-05	5	37	2	17962413
Pubmed	Mast cell IL-4 expression is regulated by Ikaros and influences encephalitogenic Th1 responses in EAE.	GATA2 GATA1	1.10e-05	5	37	2	16628252
Pubmed	Interaction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signaling.	GATA2 GATA3	1.10e-05	5	37	2	15016828
Pubmed	Spatiotemporal Role of Transforming Growth Factor Beta 2 in Developing and Mature Mouse Hindbrain Serotonergic Neurons.	GATA2 GATA3	1.65e-05	6	37	2	31619968
Pubmed	Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators.	GATA2 GATA1	1.65e-05	6	37	2	21571218
Pubmed	Gfi-1B promoter remains associated with active chromatin marks throughout erythroid differentiation of human primary progenitor cells.	GATA2 GATA1	1.65e-05	6	37	2	19522008
Pubmed	Initiation of murine embryonic erythropoiesis: a spatial analysis.	GATA2 GATA1	1.65e-05	6	37	2	9028937
Pubmed	Coexpression of SCL and GATA3 in the V2 interneurons of the developing mouse spinal cord.	GATA2 GATA3	1.65e-05	6	37	2	12112475
Pubmed	Gata2 specifies serotonergic neurons downstream of sonic hedgehog.	GATA2 GATA3	1.65e-05	6	37	2	14973276
Pubmed	Abundant expression of transcription factor GATA-2 in proliferating but not in differentiated mast cells in tissues of mice: demonstration by in situ hybridization.	GATA2 GATA1	1.65e-05	6	37	2	8562971
Pubmed	Partially overlapping expression of Gata2 and Gata3 during inner ear development.	GATA2 GATA3	2.30e-05	7	37	2	15499560
Pubmed	Sox7-sustained expression alters the balance between proliferation and differentiation of hematopoietic progenitors at the onset of blood specification.	GATA2 GATA1	3.07e-05	8	37	2	19801444
Pubmed	Etv2/ER71 induces vascular mesoderm from Flk1+PDGFRα+ primitive mesoderm.	GATA2 GATA1	3.07e-05	8	37	2	21911838
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	TAOK2 GATA3 ZFHX3 CAD PLK1 ZNF646	3.23e-05	583	37	6	29844126
Interaction	ZFPM2 interactions	GATA2 GATA3 GATA1	1.81e-05	28	37	3	int:ZFPM2
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	GATA2 GATA3 GATA1	8.10e-07	15	23	3	82
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_100	GATA2 GATA3 ZFHX3 MUC4	2.08e-05	99	35	4	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_100
ToppCell	367C-Lymphocytic-ILC-ILC-3\|367C / Donor, Lineage, Cell class and subclass (all cells)	GATA3 MTBP PPIP5K1 PABPC3	7.78e-06	153	37	4	9d64aadbb4bb28469af1d728457b431e21577429
ToppCell	facs-Spleen-nan-18m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA3 ZFHX3 TMPRSS6 MYO1F	8.62e-06	157	37	4	a84377028c661f8f3ecae0f6082abdd859faf0c8
ToppCell	wk_15-18-Hematologic-Meg-ery-Platelet\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	GATA2 CTNS HERC1 GATA1	9.28e-06	160	37	4	768f3cefc3ad4cda229e598cce8bde574cf64bb2
ToppCell	facs-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l26\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GATA2 TMEM8B CIAO3 GATA1	1.05e-05	165	37	4	23955e3373660f827518e723ac62fba99753f375
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ALPK3 PLCB1 ATP1B2 TMPRSS6	1.44e-05	179	37	4	7ae67e1c09a4ce9b3bcec4c48ee9cf2b1cb4e339
ToppCell	droplet-Spleen-nan-21m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP1B2 PLK1 TMPRSS6 GATA1	1.64e-05	185	37	4	239cc5184825b3cc98638d4aec0a1de8e508d76c
ToppCell	facs-Marrow-KLS-24m-Hematologic-MPP_Fraction_A_+_HSC\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA2 ATP1B2 TMPRSS6 GATA1	1.68e-05	186	37	4	f14722ecc832794dc267bf3f9b8a13274c3addc1
ToppCell	droplet-Spleen-nan-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP1B2 PLK1 TMPRSS6 GATA1	1.71e-05	187	37	4	c81d11d9fdc22dc39222f62c2888025c2e8c3e65
ToppCell	droplet-Spleen-SPLEEN-30m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP1B2 PLK1 TMPRSS6 GATA1	1.71e-05	187	37	4	dceca7ae3dae96078cccc17a0d8a61b06fa6dffb
ToppCell	droplet-Spleen-nan-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP1B2 PLK1 TMPRSS6 GATA1	1.82e-05	190	37	4	a273fc119baebc11020009c923beafeebb6428c9
Drug	D and C Red No. 9	GATA2 CTNS GATA1	7.91e-07	12	36	3	CID009570201
Drug	15d-PGJ2; Down 200; 10uM; MCF7; HT_HG-U133A	TAOK2 GATA2 GATA3 ZNF512B CTNS	1.09e-05	187	36	5	6948_DN
Drug	gentamicin	TAOK2 PLCB1 FNDC3A CTNS CSAD	1.43e-05	198	36	5	CID000003467
Disease	myelodysplastic syndrome (is_marker_for)	GATA2 PLCB1 GATA1	1.87e-06	20	36	3	DOID:0050908 (is_marker_for)
Disease	Hematopoetic Myelodysplasia	GATA2 PLCB1 GATA1	5.96e-06	29	36	3	C2713368
Disease	mucinous adenocarcinoma (is_marker_for)	ZFHX3 MUC4	1.44e-05	5	36	2	DOID:3030 (is_marker_for)
Disease	acute myeloid leukemia (is_marker_for)	GATA2 PLCB1 GATA1	2.96e-05	49	36	3	DOID:9119 (is_marker_for)
Disease	MYELODYSPLASTIC SYNDROME	GATA2 PLCB1 GATA1	7.57e-05	67	36	3	C3463824
Disease	depressive disorder (is_implicated_in)	GATA2 GATA1	1.95e-04	17	36	2	DOID:1596 (is_implicated_in)
Disease	sexual dimorphism measurement	TAOK2 ALPK3 ZFHX3 HERC1 ATP1B2 CIAO3 MYO1F	3.28e-04	1106	36	7	EFO_0021796
Disease	myelodysplastic syndrome (is_implicated_in)	GATA2 PLCB1	6.16e-04	30	36	2	DOID:0050908 (is_implicated_in)
Disease	clear cell renal cell carcinoma (is_marker_for)	GATA2 GATA1	7.46e-04	33	36	2	DOID:4467 (is_marker_for)
Disease	hepatocellular carcinoma (implicated_via_orthology)	BECN2 CAD	1.64e-03	49	36	2	DOID:684 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
NHYKRIYNNIPANLR	CLPX	196	O76031
RYCGLPKYEITHQGN	ALPK3	321	Q96L96
QLINCPDYKLRPYQH	ANO9	311	A1A5B4
NGQQLYRHIYLGCKE	EFR3A	526	Q14156
DKPYLCALYQQRRPH	MUC4	4656	Q99102
IQAQKNDVCRPGRYY	ATP1B2	121	P14415
RYQPGKHLSEVYRCV	HERC1	1286	Q15751
YHRLNPDYERLKIQC	DLG5	181	Q8TDM6
YKYAAGVRNPQQHRN	PABPC3	506	Q9H361
RRRYPIHQTQYSCPG	POM121C	206	A8CG34
QFQRYRLIPCGNHSY	BECN2	306	A8MW95
ACGLYYKLHQVNRPL	GATA1	281	P15976
NACGLYYKLHNVNRP	GATA2	371	P23769
CGLYYKLHNINRPLT	GATA3	341	P23771
YRGPCHTYKVQRLNE	FNDC3A	1001	Q9Y2H6
NLARYQRYPDCKQRG	CSAD	161	Q9Y600
ELPRVTRCHNYKINY	GCNA	626	Q96QF7
IQHFCLYRKRPGYDQ	CTNS	351	O60931
CLRLGKVPHRYQSGY	METTL8	11	Q9H825
HGGIINTLQKYYCRV	DEFB103A	21	P81534
YYLLLQGNGNRRCKA	MTBP	401	Q96DY7
TIPGYAIYKLIRNHC	SLC6A19	596	Q695T7
YRQILKHPCNLSYQL	PUS7L	641	Q9H0K6
QKLRHPNTIQYRGCY	TAOK2	81	Q9UL54
LVQRLKRGRCPYHYV	CIAO3	376	Q9H6Q4
CYAYGKLLQRINHGR	ZNF793	166	Q6ZN11
RCYPNLAAYRNHLRN	ZNF646	1086	O15015
GPYGQCKLLRTHNYL	TMEM8B	191	A6NDV4
RPYKCHQYGKVFIQS	ZNF705G	226	A8MUZ8
YHYICLRNERNQPLT	PLCB1	771	Q9NQ66
TYKMRYGNRGHNQPC	CAD	266	P27708
YQYHQRRCGKPPCEV	ZNF512B	611	Q96KM6
VNKLHPLCYLRYSRG	PPIP5K1	811	Q6PFW1
YALRRQKYDLPCTQG	TMPRSS6	386	Q8IU80
LPVSDRHVYKYRCNQ	ZFHX3	1391	Q15911
YLRQIVLGCQYLHRN	PLK1	156	P53350
THGPRCRALYQYVGQ	MYO1F	1041	O00160