Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainCytoplasmic_FMR1-int

CYFIP1 CYFIP2

1.55e-052742IPR008081
DomainFragX_IP

CYFIP1 CYFIP2

1.55e-052742PF05994
DomainFascin

FSCN3 FSCN1

4.63e-053742PF06268
DomainFascin

FSCN3 FSCN1

4.63e-053742IPR010431
DomainFascin_metazoans

FSCN3 FSCN1

4.63e-053742IPR024703
DomainFascin-domain

FSCN3 FSCN1

4.63e-053742IPR022768
DomainDUF1394

CYFIP1 CYFIP2

9.24e-054742PF07159
DomainActin_cross-linking

FSCN3 FSCN1

9.24e-054742IPR008999
DomainDUF1394

CYFIP1 CYFIP2

9.24e-054742IPR009828
DomainKelch-typ_b-propeller

KLHL35 KLHL14 LCMT2

1.35e-0355743IPR015915
DomainBTB

RHOBTB2 KLHL35 SPOP KLHL14

1.82e-03131744PF00651
DomainBTB

RHOBTB2 KLHL35 SPOP KLHL14

3.75e-03160744PS50097
DomainBTB

RHOBTB2 KLHL35 SPOP KLHL14

5.68e-03180744SM00225
DomainBTB/POZ_dom

RHOBTB2 KLHL35 SPOP KLHL14

6.25e-03185744IPR000210
DomainFN3

PAPPA2 ASTN1 OSMR CDON

6.25e-03185744SM00060
DomainSKP1/BTB/POZ

RHOBTB2 KLHL35 SPOP KLHL14

6.74e-03189744IPR011333
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

EEF1G CYFIP1 ACACA POLR1C BAZ1B PLCG1 MTREX FSCN1 AP3B1 BIRC6

3.11e-06704761029955894
Pubmed

Different dysregulations of CYFIP1 and CYFIP2 in distinct types of dementia.

CYFIP1 CYFIP2

4.71e-06276238128786
Pubmed

Cytoplasmic FMRP interacting protein 1/2 (CYFIP1/2) expression analysis in autism.

CYFIP1 CYFIP2

4.71e-06276229752658
Pubmed

C57BL/6N mutation in cytoplasmic FMRP interacting protein 2 regulates cocaine response.

CYFIP1 CYFIP2

4.71e-06276224357318
Pubmed

Testis fascin (FSCN3): a novel paralog of the actin-bundling protein fascin expressed specifically in the elongate spermatid head.

FSCN3 FSCN1

4.71e-06276211925108
Pubmed

Cytoplasmic FMR1 interacting protein (CYFIP) family members and their function in neural development and disorders.

CYFIP1 CYFIP2

4.71e-06276234327661
Pubmed

Protein interactome and cell-type expression analyses reveal that cytoplasmic FMR1-interacting protein 1 (CYFIP1), but not CYFIP2, associates with astrocytic focal adhesion.

CYFIP1 CYFIP2

4.71e-06276235567753
Pubmed

Cyfip1 Haploinsufficiency Increases Compulsive-Like Behavior and Modulates Palatable Food Intake in Mice: Dependence on Cyfip2 Genetic Background, Parent-of Origin, and Sex.

CYFIP1 CYFIP2

4.71e-06276231324746
Pubmed

Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.

CYFIP1 ASPH BAZ1B FSCN1 AP3B1 HERC5

1.11e-0522876630471916
Pubmed

Expression of vascular endothelial growth factor, CD10, and factor 8 in phyllodes tumor: A 5-year study of 38 cases.

F8 VEGFA

1.41e-05376233342805
Pubmed

Oxidative stress mediates the disruption of airway epithelial tight junctions through a TRPM2-PLCγ1-PKCα signaling pathway.

TRPM2 PLCG1

1.41e-05376223629676
Pubmed

Fascin1 is dispensable for mouse development but is favorable for neonatal survival.

FSCN3 FSCN1

1.41e-05376219343791
Pubmed

Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination.

ZAP70 OTUD7B

1.41e-05376226903241
Pubmed

Human EP3(I) prostanoid receptor induces VEGF and VEGF receptor-1 mRNA expression.

PTGER3 VEGFA

1.41e-05376218996083
Pubmed

Localization of phospholipase C-gamma 1 to mouse chromosome 2.

PLCG1 PCK1

1.41e-0537621358284
Pubmed

Characterization of human retinal fascin gene (FSCN2) at 17q25: close physical linkage of fascin and cytoplasmic actin genes.

FSCN3 FSCN1

1.41e-05376210783262
Pubmed

Immunoreactivity for GABA, GAD65, GAD67 and Bestrophin-1 in the meninges and the choroid plexus: implications for non-neuronal sources for GABA in the developing mouse brain.

BEST1 RDH10

2.82e-05476223437266
Pubmed

Rab25 augments cancer cell invasiveness through a β1 integrin/EGFR/VEGF-A/Snail signaling axis and expression of fascin.

FSCN1 VEGFA

2.82e-05476229371698
Pubmed

Tyrosine phosphorylation and recruitment of ZAP-70 to the CD3-TCR complex are defective after CD2 stimulation.

PLCG1 ZAP70

2.82e-0547628906806
Pubmed

Retrolinkin recruits the WAVE1 protein complex to facilitate BDNF-induced TrkB endocytosis and dendrite outgrowth.

CYFIP1 CYFIP2

2.82e-05476227605705
Pubmed

Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN.

CYFIP1 CYFIP2

2.82e-05476220228810
Pubmed

Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability.

ACACA PCK1

2.82e-05476238447582
Pubmed

Interchangeable functions of Arabidopsis PIROGI and the human WAVE complex subunit SRA1 during leaf epidermal development.

CYFIP1 CYFIP2

2.82e-05476215294869
Pubmed

RIM1/2 in retinal ganglion cells are required for the refinement of ipsilateral axons and eye-specific segregation.

RIMS1 AP3B1

4.69e-05576228607399
Pubmed

GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development.

PLCG1 ZAP70

4.69e-05576223460737
Pubmed

Ligation of the T-cell antigen receptor (TCR) induces association of hSos1, ZAP-70, phospholipase C-gamma 1, and other phosphoproteins with Grb2 and the zeta-chain of the TCR.

PLCG1 ZAP70

4.69e-0557627629168
Pubmed

Differential expression and molecular associations of Syk in systemic lupus erythematosus T cells.

PLCG1 ZAP70

4.69e-05576219018007
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

EEF1G CYFIP1 ACACA TM9SF2 MYO1D BAZ1B PLCG1 MTREX MED23 AP3B1 PDXK CYFIP2

5.85e-051425761230948266
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

EEF1G ABCB7 CYFIP1 GLE1 ASPH SLC35E1 BAZ1B ACVR1 GOLGA5 MED23 CYFIP2

5.92e-051203761129180619
Pubmed

A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P.

CYFIP1 CYFIP2

7.03e-05676211438699
Pubmed

Recruitment and activation of PLCgamma1 in T cells: a new insight into old domains.

PLCG1 ZAP70

7.03e-05676216467851
Pubmed

VE-cadherin facilitates BMP-induced endothelial cell permeability and signaling.

ACVR1 VEGFA

7.03e-05676226598555
Pubmed

Differential cell-type-expression of CYFIP1 and CYFIP2 in the adult mouse hippocampus.

CYFIP1 CYFIP2

7.03e-05676231853374
Pubmed

High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.

EEF1G CYFIP1 MYO1D ASPH POLR1C MTREX AP3B1

7.60e-0546976737314180
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ABCB7 PTPMT1 SLC25A40 ASPH POLR1C BAZ1B GOLGA5 FSCN1 AP3B1 TTK LCMT2 HERC5

8.78e-051487761233957083
Pubmed

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b.

PLCG1 ZAP70

9.83e-05776210646608
Pubmed

4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.

PTPMT1 HERC5

9.83e-05776236575176
Pubmed

Smaller Body Size, Early Postnatal Lethality, and Cortical Extracellular Matrix-Related Gene Expression Changes of Cyfip2-Null Embryonic Mice.

CYFIP1 CYFIP2

9.83e-05776230687000
Pubmed

Adipocyte STAT5 deficiency promotes adiposity and impairs lipid mobilisation in mice.

ACACA PCK1

9.83e-05776227858140
Pubmed

Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells.

PLCG1 ZAP70

9.83e-05776212084069
Pubmed

Sequential phosphorylation of SLP-76 at tyrosine 173 is required for activation of T and mast cells.

PLCG1 ZAP70

9.83e-05776221725281
Pubmed

Regulation of NK cell-mediated cytotoxicity by the adaptor protein 3BP2.

PLCG1 ZAP70

1.31e-04876211390470
Pubmed

Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells.

PLCG1 ZAP70

1.31e-04876211368773
Pubmed

An airway-to-brain sensory pathway mediates influenza-induced sickness.

PIEZO2 PTGER3

1.31e-04876236890237
Pubmed

Adaptor function for the Syk kinases-interacting protein 3BP2 in IL-2 gene activation.

PLCG1 ZAP70

1.31e-0487629846481
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

EEF1G CYFIP1 SETD1B ACACA ASPH POLR1C BAZ1B PLCG1 MTREX FSCN1 BIRC6

1.67e-041353761129467282
Pubmed

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation.

PLCG1 ZAP70

1.68e-0497629489702
Pubmed

EphB6-null mutation results in compromised T cell function.

PLCG1 ZAP70

1.68e-04976215599401
Pubmed

Human immunodeficiency virus type 1 envelope gp120-induced partial T-cell receptor signaling creates an F-actin-depleted zone in the virological synapse.

PLCG1 ZAP70

1.68e-04976219710135
Pubmed

Neurodevelopmental disorder-associated CYFIP2 regulates membraneless organelles and eIF2α phosphorylation via protein interactors and actin cytoskeleton.

CYFIP1 CYFIP2

1.68e-04976238981622
Pubmed

Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub.

PLCG1 ZAP70

1.68e-04976224584089
Pubmed

Stromal-cell-derived factor-1/CXCL12-induced chemotaxis of a T cell line involves intracellular signaling through Cbl and Cbl-b and their regulation by Src kinases and CD45.

PLCG1 ZAP70

2.10e-041076216503409
Pubmed

Abi1 is essential for the formation and activation of a WAVE2 signalling complex.

CYFIP1 CYFIP2

2.10e-041076215048123
Pubmed

A phenotype-driven ENU mutagenesis screen identifies novel alleles with functional roles in early mouse craniofacial development.

RDH10 MED23

2.10e-041076221305688
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

GLE1 ASPH POLR1C BAZ1B MTREX MED23 BIRC6 HERC5

2.53e-0475976835915203
Pubmed

Lipopenia and skin barrier abnormalities in DGAT2-deficient mice.

ACACA PCK1

2.56e-041176214668353
Pubmed

Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation.

DOK4 PLCG1

2.56e-041176211470823
Pubmed

Transcriptome analysis of human gastric cancer.

PTPMT1 CORO2A GLE1 BTD ASPH POLR1C ZNF264 PCK1

2.84e-0477276816341674
Pubmed

Partial functional redundancy between Hoxa5 and Hoxb5 paralog genes during lung morphogenesis.

HOXA5 VEGFA

3.07e-041276223585229
Pubmed

A pathway sensor for genome-wide screens of intracellular proteolytic cleavage.

ASPH CYFIP2

3.07e-041276218387192
Pubmed

Deficiency of the neurodevelopmental disorder-associated gene Cyfip2 alters the retinal ganglion cell properties and visual acuity.

CYFIP1 CYFIP2

3.62e-041376234508581
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

EEF1G CYFIP1 SLC25A40 ASPH POLR1C SLC35E1 BAZ1B MTREX MED23 AP3B1 CYFIP2

3.96e-041497761131527615
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

EEF1G ABCB7 CYFIP1 PTPMT1 ACACA POLR1C SLC35E1 GNB4 BIRC6 PDXK

4.02e-041257761037317656
Pubmed

Loss of the placental iron exporter ferroportin 1 causes embryonic demise in late-gestation mouse pregnancy.

ERVW-1 SLC40A1

4.22e-041476236398730
Pubmed

Thirteen genes (Cebpb, E2f1, Tcf4, Cyp24, Pck1, Acra4, Edn3, Kcnb1, Mc3r, Ntsr, Cd40, Plcg1 and Rcad) that probably lie in the distal imprinting region of mouse chromosome 2 are not monoallelically expressed.

PLCG1 PCK1

4.22e-04147627781998
Pubmed

Placental vasculogenesis is regulated by keratin-mediated hyperoxia in murine decidual tissues.

ERVW-1 VEGFA

4.22e-041476221435445
Pubmed

Genetic interaction mapping in mammalian cells using CRISPR interference.

SETD1B MRGBP MED23

4.74e-046976328481362
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

EEF1G ABCB7 CYFIP1 ACACA TM9SF2 ASPH GNB4 BIRC6 TTK PDXK

5.13e-041297761033545068
Pubmed

Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis.

BAZ1B GNB4 MTREX

5.37e-047276333106477
Pubmed

Intestinal SURF4 is essential for apolipoprotein transport and lipoprotein secretion.

ACACA PCK1

5.54e-041676238042368
Pubmed

A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta.

ERVW-1 VEGFA

5.54e-041676223610556
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

EEF1G ACACA POLR1C BAZ1B PLCG1 MTREX AP3B1

5.68e-0465376733742100
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ACACA MYO1D BAZ1B MTREX FSCN1 BIRC6 HERC5

5.68e-0465376722586326
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

EEF1G ABCB7 CYFIP1 ACACA MYO1D BAZ1B

6.76e-0448476631995728
Pubmed

In mouse brain profilin I and profilin II associate with regulators of the endocytic pathway and actin assembly.

CYFIP1 CYFIP2

7.05e-04187629463375
Pubmed

Transcription factor TLX1 controls retinoic acid signaling to ensure spleen development.

RDH10 VEGFA

7.05e-041876227214556
Pubmed

Morphogenetic competence of HNF4 alpha-deficient mouse hepatic cells.

OSMR PCK1

7.05e-041876218617288
Pubmed

14-3-3-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking.

EEF1G ACACA MTREX OPLAH

7.53e-0418676414744259
Pubmed

Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

POLR1C ZNF264 PLCG1 GOLGA5 ZAP70

7.63e-0432776515592455
Pubmed

Genome-wide association study of circulating estradiol, testosterone, and sex hormone-binding globulin in postmenopausal women.

BEST1 CYP4B1

7.87e-041976222675492
Pubmed

Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?

ACACA DDC PCK1 VEGFA

8.47e-0419276420602615
Pubmed

Tagging genes with cassette-exchange sites.

BAZ1B MED23 FSCN1 AP3B1 BIRC6

8.50e-0433576515741177
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

EEF1G CYFIP1 MYO1D MRGBP TTK CYFIP2

8.52e-0450676630890647
Pubmed

A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes.

ACACA BIRC6 OTUD7B

9.63e-048876327182664
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

EEF1G CYFIP1 PTPMT1 ACACA ASPH POLR1C MTREX FSCN1 AP3B1 BIRC6

1.00e-031415761028515276
Pubmed

A quantitative protein interaction network for the ErbB receptors using protein microarrays.

DOK4 PLCG1 ZAP70

1.03e-039076316273093
Pubmed

NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons.

CYFIP1 CYFIP2

1.06e-032276221946561
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PITPNM2 EEF1G CYFIP1 MYO1D CORO2A RIMS1 FSCN1 AP3B1 PDXK CYFIP2

1.09e-031431761037142655
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

HOXA5 EEF1G ABCB7 CORO2A ASPH POLR1C SLC35E1 MTREX PDXK HERC5

1.14e-031440761030833792
Pubmed

Dual Shp2 and Pten Deficiencies Promote Non-alcoholic Steatohepatitis and Genesis of Liver Tumor-Initiating Cells.

ACACA PCK1

1.16e-032376227974211
Pubmed

A UBE2O-AMPKα2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy.

ACACA VEGFA

1.16e-032376228162974
Pubmed

Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development.

ACVR1 VEGFA

1.16e-032376225759071
Pubmed

CRISPR/Cas9-mediated Genomic Editing of Cluap1/IFT38 Reveals a New Role in Actin Arrangement.

ACACA ASPH SLC35E1 FSCN1

1.24e-0321376429615496
Pubmed

Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism.

ACACA PCK1

1.26e-032476225505152
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

EEF1G OSMR CYFIP2 HERC5

1.26e-0321476422199357
Pubmed

Decidualisation and placentation defects are a major cause of age-related reproductive decline.

ERVW-1 PTGER3

1.37e-032576228874785
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

ABCB7 CYFIP1 ASPH MTREX MED23 AP3B1

1.43e-0356076635241646
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PITPNM2 BEST1 ACACA TRPM2 ASPH RDH10 KATNIP RIMS1 PLCG1 PDXK

1.46e-031489761028611215
Pubmed

Placentation defects are highly prevalent in embryonic lethal mouse mutants.

MED23 CYFIP2 OTUD7B

1.52e-0310376329539633
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

EEF1G ACACA GOLGA5 AP3B1 BIRC6 CDON OTUD7B

1.56e-0377776735844135
GeneFamilyFascins

FSCN3 FSCN1

2.52e-0535323
GeneFamilyBasic leucine zipper proteins|BTB domain containing

RHOBTB2 KLHL35 SPOP KLHL14

6.38e-04134534861
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000

PAPPA2 ZNF23 ASPH RDH10 BAZ1B ASTN1 ACVR1 FSCN1 PTGER3 BIRC6 DDC VEGFA

1.56e-058187112gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
ToppCellfacs-Lung-nan-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 TM9SF2 CYP4B1 PLCG1 MTREX F8

1.04e-061957667f9b7f15006610ad591063d90e90367bd6083c7f
ToppCellAT1-AT2_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

CYP4B1 MAB21L4 RHOBTB2 ERVW-1 VEGFA

1.24e-05175765bdd85ba280648a0283c1984662a34c7b840f64dd
ToppCellRA-11._Adipocyte|RA / Chamber and Cluster_Paper

ACACA ASPH PTGER3 PCK1 PDXK

1.42e-05180765d48a3d27357f7d184132a6805950f93080146b59
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ACACA MYO1D ASPH POLR1C OSMR

1.46e-05181765576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCellLA-11._Adipocyte|World / Chamber and Cluster_Paper

ACACA ASPH PTGER3 PCK1 PDXK

1.54e-05183765b177be283e1553fb1f69a346f1ba79ad00297fa2
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

ACACA ASPH PTGER3 PCK1 PDXK

1.54e-051837653f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO1D CYP4B1 MAB21L4 OTUD7B VEGFA

1.62e-051857651c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellE17.5-Endothelial-unknown_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PIEZO2 DOK4 CYP4B1 GNB4 FSCN1

1.71e-05187765da885c26ccc5189b1ff1f607552e00a5c0e49e7e
ToppCellE17.5-Endothelial-unknown_endothelial_cell-endothelial_unknown_1|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PIEZO2 DOK4 CYP4B1 GNB4 FSCN1

1.71e-051877651f358d02ec69d44dea2e2831af9473ed05dcf8cc
ToppCellRA-11._Adipocyte|World / Chamber and Cluster_Paper

ACACA ASPH PTGER3 PCK1 PDXK

1.75e-051887654dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYFIP1 TM9SF2 ASPH MTREX FSCN1

1.80e-051897656dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYFIP1 TM9SF2 ASPH MTREX FSCN1

1.80e-051897653ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYFIP1 TM9SF2 ASPH MTREX FSCN1

1.80e-05189765875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCellfacs-Brain_Myeloid-Striatum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYFIP1 TM9SF2 ASPH MTREX FSCN1

1.80e-0518976597ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ASTN1 PTGER3 SLC40A1 PCK1 CDON

2.04e-05194765421344cc4b601d9745fa72d0af3124dab11d1d27
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4B1 OSMR MTREX FSCN1 F8

2.20e-05197765deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4B1 OSMR MTREX FSCN1 F8

2.20e-05197765a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4B1 OSMR MTREX FSCN1 F8

2.25e-05198765f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MYO1D DOK4 CYP4B1 MAB21L4 VEGFA

2.30e-05199765d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_1-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CYP4B1 MAB21L4 RHOBTB2 ERVW-1 VEGFA

2.30e-05199765c1daa481f88d5281b6b5ea8ec8bb70cc0907d613
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CYP4B1 MAB21L4 RHOBTB2 SLC40A1 VEGFA

2.36e-05200765cbe3e107ac16c17687d73ebb04c39d51aba1fa98
ToppCellHippocampus-Macroglia-OLIGODENDROCYTE-O2-Trf|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYO1D FAM186A DDC OTUD7B

7.71e-05132764dc6edfa821a1cdc645668b0af5ba5ff80dee10bd
ToppCellHippocampus-Macroglia-OLIGODENDROCYTE-O2|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYO1D FAM186A DDC OTUD7B

7.71e-0513276460ced08bda5efc95a6f116cd0c6d1a779d99ed38
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CORO2A DDC KLRC1 ZAP70

1.02e-04142764efe2418436ad1320b8e8fce38619ac65516ef077
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOK4 RDH10 F8 KLRC1

1.26e-041507646785b695a01de47a47f5c94fdc432428ef80bada
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOK4 RDH10 F8 KLRC1

1.26e-04150764ddfb7dd696f06e834c45d6c3f9b1138bc17d62b3
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF23 PTGER3 CYFIP2 OPLAH

1.36e-041537640307f10e772021ae68a42690634df458672a6df9
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4B1 KLRC1 ZAP70 CDON

1.43e-04155764c58a5fb8d853f12204e961d633e83452eb12a659
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4B1 KLRC1 ZAP70 CDON

1.43e-041557649cb8c42c2e451b2d4dcd7154a4b1bfd21bbb7ea8
ToppCellfacs-SCAT-Fat-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL35 KLRC1 ZAP70 CYFIP2

1.51e-04157764ad8c6eb34f5288288c4066119c17325afefbaafc
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CYFIP1 GNB4 PTGER3 HERC5

1.54e-04158764216b3f482daa2d0d7fcaf5a8559e3ccbdb8e110d
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CORO2A KLRC1 ZAP70 CYFIP2

1.54e-041587648844fba9c1e41f062edf3110d025f33b86afb951
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CYFIP1 GNB4 PTGER3 HERC5

1.54e-041587649712bb8b1bacb8a38c99a22bc2babec5d5160e2a
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CORO2A KLRC1 ZAP70 CYFIP2

1.54e-04158764c56607cba9a3719ac6d573d970686053e1676985
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

BTD PLCG1 SLC40A1 ZAP70

1.58e-04159764b1d5ebd0c186b6d0279dab20d8f3b4a915acdc1f
ToppCellfacs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-natural_killer|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CORO2A KLRC1 ZAP70 CYFIP2

1.62e-04160764e4516b093003275084fc327d1597394a436754eb
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BAZ1B KATNIP KLRC1 ZAP70

1.62e-041607646b0faaa371650563f585722f5b2fb319e124ec38
ToppCellfacs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CORO2A KLRC1 ZAP70 CYFIP2

1.62e-041607640a507e3d59d7f744d0201a531ea84fa97a68aedb
ToppCellfacs-Lung-18m-Hematologic-Lymphocytic_NK_ILC|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CORO2A KLRC1 ZAP70 CYFIP2

1.70e-0416276404ccd3d216f8f41afd3434a61264f03d6324db35
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BTD ACVR1 KLRC1 ZAP70

1.74e-0416376413f76f2979558f5cd27fbfd1659b413b3cac18f5
ToppCellHealthy_Control-Lymphoid-T-innate_T|Healthy_Control / Condition, Lineage, Cell class and cell subclass

PITPNM2 KLRC1 ZAP70 OTUD7B

1.82e-041657641ade67229b50fe20eb392262a3e1ee4306b73290
ToppCellBronchial_Biopsy-Immune-T_and_NK|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

PIEZO2 PLCG1 PTGER3 TTK

1.95e-04168764435b2f238fbb3f50427e8cdecf2220615015153c
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CORO2A KLRC1 ZAP70 CYFIP2

2.00e-041697648028622ff362d70d1002e65a74ade46ea7f1f13f
ToppCelldroplet-Fat-Scat-21m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXA5 PITPNM2 CYP4B1 PCK1

2.18e-04173764f13124b4cf2ac1dc2895f90f5487d6ac681b0ba4
ToppCellEndothelial-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

PIEZO2 PLCG1 KLHL14 FSCN1

2.18e-04173764a81992965137195d20fc498f750975303961a828
ToppCelldroplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Epithelial-Enterocyte|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGQ CORO2A CYP4B1 VEGFA

2.33e-04176764ce950805aaa3d39630376028ecd7da584fdb4394
ToppCellfacs-Aorta|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXA5 CYP4B1 F8 PCK1

2.33e-041767640b3491451be02c18a16cdb875645be47eb867a7f
ToppCelldroplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGQ CORO2A CYP4B1 VEGFA

2.33e-041767645b65693833e02c08530488cbe37883e7c75f312e
ToppCellRV-11._Adipocyte|World / Chamber and Cluster_Paper

ASPH PTGER3 PCK1 PDXK

2.38e-04177764f0edf04930692418953e4f00a917257804ec0ffd
ToppCellfacs-Heart-RA-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CORO2A KLRC1 ZAP70 CYFIP2

2.38e-0417776431201a72b7c1bdb0eff892b7072a35c80fd34727
ToppCellfacs-Heart-RA-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CORO2A KLRC1 ZAP70 CYFIP2

2.38e-0417776489d0131320cd96af8b0ee54f0f4d4771d17ef44e
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

PIEZO2 KLHL14 FSCN1 F8

2.43e-04178764c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 KLHL14 FSCN1 F8

2.43e-04178764ad3de3e03a401dac64431a541899445262246347
ToppCellfacs-Heart-RA-3m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CORO2A KLHL14 KLRC1 ZAP70

2.43e-04178764ba6ded4455233635a11afcf6f522c786bd81b5e0
ToppCell10x5'v1-week_17-19-Lymphocytic_NK-T_NK-ILC_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

HOXA5 DOK4 KLRC1 ZAP70

2.49e-04179764d18a520568cf4b031972d3dd7d4d4bd073ac1fea
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4B1 GNB4 OSMR F8

2.59e-041817644df7972f88117108698efd06b124b232f8588981
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO1D CYP4B1 MAB21L4 VEGFA

2.59e-04181764b45b11428d13950369347e051d4d517efb2bd4fd
ToppCelldroplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGQ CORO2A CYP4B1 VEGFA

2.59e-04181764a52e367f0909689174b3534f0cd51f36abe1b49f
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4B1 GNB4 OSMR F8

2.59e-04181764cbb530566893281289026bfd93adf721decd4ca3
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 KLHL14 FSCN1 F8

2.65e-0418276453c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 KLHL14 FSCN1 F8

2.70e-041837644d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

MYO1D CYP4B1 RHOBTB2 VEGFA

2.70e-04183764942530449e9c6583705eeb8f6f12621daea57252
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO1D CYP4B1 OTUD7B VEGFA

2.76e-0418476457c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellfacs-Brain_Myeloid-Cortex|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FSCN1 PTGER3 SLC40A1 PCK1

2.76e-0418476417f63dd671f9ff3dd2860d8de41b05c35c095950
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO1D CYP4B1 OTUD7B VEGFA

2.76e-04184764d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCelltumor_Lung-Fibroblasts-Mesothelial_cells|tumor_Lung / Location, Cell class and cell subclass

PIEZO2 PTGER3 PCK1 CDON

2.76e-04184764b0a251030d127858e68cf164be158f209a4d720f
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ASPH CYFIP2 CDON VEGFA

2.82e-041857640d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellCOVID-CD4-CD8_1|COVID / Condition, Cell_class and T cell subcluster

PIGQ CORO2A RDH10 MRGBP

2.82e-04185764c634bb04a081ae3214b68f6e4a147db5b2b916ed
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 KLHL14 FSCN1 F8

2.88e-0418676440070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXA5 CYP4B1 GNB4 F8

2.88e-0418676437860daeecd6d412bd3797f30496a56da667fbd1
ToppCellP07-Endothelial-capillary_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PIEZO2 DOK4 CYP4B1 FSCN1

2.88e-0418676472aab20b848dd9e1101a4bc2466e08aed5f8bbb6
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXA5 CYP4B1 GNB4 F8

2.88e-0418676460830822d3de3147816693404fd03392e04c2b8e
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXA5 CYP4B1 GNB4 F8

2.88e-04186764baebeffdd426ce767190ddefc857cc78e6a58d36
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ABCB7 BAZ1B MED23 VEGFA

2.94e-04187764689b3cc76f1e04bd35a7d3ce19e9f08744a7835b
ToppCellE17.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PIEZO2 DOK4 CYP4B1 FSCN1

2.94e-04187764e9aa0a5a0f8e2593de63e83b56b53ae33e60af49
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ABCB7 BAZ1B MED23 VEGFA

2.94e-041877644527d6426f2c4397e47f12439a13a8c14fd2aab2
ToppCellE17.5-Endothelial-capillary_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PIEZO2 DOK4 CYP4B1 FSCN1

2.94e-0418776461b8a53f29bb8b33c69f680b8359a1143a23999d
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR20 ASTN1 GNB4 PTGER3

2.94e-04187764dba4924d914a7dcd4901142684ba920c2404860b
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR20 ASTN1 GNB4 PTGER3

2.94e-041877649688141beef4f62613d7a810c5872ccb9afc1a71
ToppCellASK454-Epithelial-Type_1|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

MYO1D CYP4B1 MAB21L4 VEGFA

3.00e-0418876413f8ce8f24ac7d7ed87f4ae3b8f4096de29383c2
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PIEZO2 KLHL14 FSCN1 F8

3.00e-041887642db80767903703e7e0a1a37c598f7877a909ee94
ToppCellASK454-Endothelial-Lymphatic|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq

BEST1 PIEZO2 PLCG1 HERC5

3.06e-04189764316c857dec9383823e09f966bca62d52d933b141
ToppCellEC-Sinusoidal_ECs|World / Lineage and Cell class

DOK4 CYP4B1 FSCN1 F8

3.06e-041897649a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP4B1 MAB21L4 ERVW-1 VEGFA

3.12e-041907648ceb327dc995f4b83b05d5d6630e1294f0cb49bd
ToppCellE17.5-Endothelial|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PIEZO2 DOK4 CYP4B1 FSCN1

3.12e-041907644fb76195ec9d6e0260a628eef6c2b3705acce787
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP4B1 MAB21L4 SLC40A1 VEGFA

3.18e-04191764a15e34ad7dbf3f2f13d5e23ce3ffb6d08fd1f9f0
ToppCellwk_15-18-Mesenchymal-Mesothelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CYP4B1 RDH10 PCK1 CDON

3.18e-04191764b5374674312ff5803a1d369f5533027532344679
ToppCellILEUM-non-inflamed-(6)_ILC3|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

HOXA5 PTGER3 KLRC1 VEGFA

3.18e-041917646eaf72b41084404bee0db04e4605db745a74995f
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EEF1G KLRC1 ZAP70 HERC5

3.18e-0419176429ce21c6e810edd51f13e0fb1083cd44bd57b1d4
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIEZO2 DOK4 CYP4B1 FSCN1

3.24e-04192764e4dd24aefdf13cd4206714f02fde2288f3173ffc
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIEZO2 DOK4 CYP4B1 FSCN1

3.24e-041927641a3f24607cb49aa610c183f4c2b7d735f484a3a4
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

ACACA MYO1D RHOBTB2 OSMR

3.24e-04192764efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP4B1 OSMR FSCN1 F8

3.24e-041927645890076929598e88fe9d59a4e4e858b446746ce9
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTGER3 PDXK CYFIP2 VEGFA

3.24e-04192764ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 TM9SF2 MTREX F8

3.24e-041927641ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIEZO2 DOK4 CYP4B1 FSCN1

3.24e-04192764c8dcd75d695d09adff083af8d5a64cf15fe027d4
ToppCellE18.5-Endothelial-Endothelial_blood-vessel|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIEZO2 DOK4 CYP4B1 FSCN1

3.24e-04192764a502e95f78f96ed060654a769c6a0cc5dc5fcfd9
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIEZO2 DOK4 CYP4B1 FSCN1

3.24e-041927643c8603f977de34ee0d2bb50635f6722112a6a4db
ToppCellE18.5-Endothelial|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIEZO2 DOK4 CYP4B1 FSCN1

3.24e-04192764cb55d30880237ab8dccf7f7bd31eb7dc5aba0583
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BEST1 RDH10 OSMR VEGFA

3.31e-04193764a313541cedfcff8fb311b9bc60157359aa103830
Drugnovobiocin sodium, USP; Up 200; 100uM; SKMEL5; HG-U133A

SETD1B SLC25A40 TRPM2 SLC35E1 SPOP GOLGA5 LCMT2

4.07e-06198757632_UP
Drugprochlorperazine dimaleate salt; Up 200; 10uM; MCF7; HT_HG-U133A

PAPPA2 ASPH BAZ1B OSMR FSCN1 VEGFA

2.79e-051797561640_UP
DrugDeptropine citrate [2169-75-7]; Down 200; 7.6uM; HL60; HT_HG-U133A

FBXO38 SLC25A40 GLE1 ASPH AP3B1 VEGFA

3.90e-051907563144_DN
Drugbutein; Up 200; 10uM; MCF7; HG-U133A

ZNF23 KLHL35 RIMS1 PTGER3 PDXK VEGFA

4.38e-05194756607_UP
Drugchlorpromazine hydrochloride; Up 200; 1uM; PC3; HT_HG-U133A

FSCN3 BAZ1B RIMS1 PLCG1 PTGER3 PCK1

4.38e-051947564441_UP
DrugSTOCK1N-35874; Up 200; 14uM; PC3; HT_HG-U133A

FBXO38 GLE1 RHOBTB2 ASPH SLC35E1 VEGFA

4.50e-051957566583_UP
DrugFlunarizine dihydrochloride [30484-77-6]; Up 200; 8.4uM; MCF7; HT_HG-U133A

PIGQ SETD1B DOK4 TRPM2 BAZ1B VEGFA

4.77e-051977567412_UP
DrugDemecarium bromide [56-94-0]; Up 200; 5.6uM; HL60; HG-U133A

PAPPA2 BTD FSCN3 TRPM2 ASPH SLC35E1

4.77e-051977561781_UP
DrugDyclonine hydrochloride [536-43-6]; Up 200; 12.2uM; PC3; HT_HG-U133A

SLC25A40 BTD ASPH BAZ1B AP3B1 PTGER3

4.90e-051987567261_UP
DrugMephenesin [59-47-2]; Down 200; 22uM; PC3; HT_HG-U133A

PAPPA2 DOK4 CORO2A BTD PLCG1 OSMR

4.90e-051987563675_DN
DrugBisoprolol fumarate; Down 200; 9uM; MCF7; HT_HG-U133A

ZNF23 GLE1 ASPH BAZ1B FSCN1 CYFIP2

4.90e-051987565348_DN
Drugrotenone; Down 200; 1uM; MCF7; HT_HG-U133A

PIGQ FBXO38 CYP4B1 BTD RHOBTB2 FSCN1

4.90e-051987565915_DN
DrugTrimethylcolchicinic acid [3482-37-9]; Down 200; 11.6uM; MCF7; HT_HG-U133A

FBXO38 MYO1D CORO2A RHOBTB2 ASPH PLCG1

5.04e-051997562802_DN
DrugAntazoline hydrochloride [2508-72-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A

SETD1B ASPH BAZ1B FSCN1 CDON VEGFA

5.04e-051997566775_UP
Drug2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A

PAPPA2 DOK4 TRPM2 ASPH PDXK CDON

5.04e-051997565219_UP
Diseasechromosome 15q11.2 deletion syndrome (implicated_via_orthology)

CYFIP1 CYFIP2

1.86e-053742DOID:0060393 (implicated_via_orthology)
Diseasecolon cancer (biomarker_via_orthology)

PLCG1 PTGER3 VEGFA

1.30e-0439743DOID:219 (biomarker_via_orthology)
DiseaseConnective Tissue Diseases

PIEZO2 ACVR1

4.75e-0413742C0009782
Diseaseschizophrenia (implicated_via_orthology)

ASTN1 TAAR1 RIMS1

6.75e-0468743DOID:5419 (implicated_via_orthology)
DiseaseBMI-adjusted waist-hip ratio, physical activity measurement

EEF1G BAZ1B VEGFA

7.04e-0469743EFO_0007788, EFO_0008002
DiseaseHemangiosarcoma

PLCG1 VEGFA

9.25e-0418742C0018923
DiseaseBipolar Disorder

TRPM2 RIMS1 PLCG1 ERVW-1 DDC VEGFA

1.27e-03477746C0005586
Diseaseportal hypertension (biomarker_via_orthology)

DDC VEGFA

1.39e-0322742DOID:10762 (biomarker_via_orthology)
Diseaseamyotrophic lateral sclerosis (is_marker_for)

MTREX VEGFA

2.41e-0329742DOID:332 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
HTYILPWESELKLMH

BIRC6

1881

Q9NR09
PAWYEKLVLEMVHHN

BAZ1B

81

Q9UIG0
LWPDMPHHTSLVVYH

GPR20

266

Q99678
STQLWLITHYHEMGS

ACVR1

276

Q04771
LHWLSYMPKSVHSSV

ACACA

1896

Q13085
SSYSGWVVEHVLPHM

GLE1

46

Q53GS7
TNIHTTLKDHMDPYW

BEST1

561

O76090
KYSIMHPGTHVWPHT

ASPH

666

Q12797
EKIIMPGVTHWHSPY

DDC

61

P20711
HYMALPEQSWHSQLL

ATG2A

1076

Q2TAZ0
YPVLQHWKVRSVMYH

ASTN1

811

O14525
VMAVAQLYWHISPKS

AP3B1

316

O00203
SSHHPWVTMNGLAFK

KLRC1

181

P26715
QWTVHNLPYHQELKM

OSMR

51

Q99650
GKYLAHWLSMAQHPA

PCK1

491

P35558
IAVIWKDSHLHIPMY

OR5H8

46

P0DN80
KLHLLHSYMNVKWIP

OTUD7B

421

Q6GQQ9
HSYMNVKWIPLSSDA

OTUD7B

426

Q6GQQ9
AHVMEVYSWKLVHPT

CYFIP1

406

Q7L576
MAVQVPLWHHYLQAI

MAB21L4

11

Q08AI8
TTLIWLSSHLHTPMY

OR8G1

46

Q15617
WVMIVLLTYTPEMHH

GOLGA5

711

Q8TBA6
TVSMIKLWNYAKTPH

KATNIP

1496

O60303
ALAIRAPHWYASHMK

PTGER3

156

P43115
IYPWMRKLHISHDNI

HOXA5

176

P20719
LQTIMSFTPHNWASH

MED23

716

Q9ULK4
IWDSYTTNKMHAIPL

GNB4

81

Q9HAV0
TKTYFWKVQHHMAPT

F8

1831

P00451
KVYHVGMHIPSWFRS

PITPNM2

61

Q9BZ72
HVMEVYSWKLVHPTD

CYFIP2

406

Q96F07
VGMAWLVSHVHSLLY

OR1K1

146

Q8NGR3
KMPLLQSSSHWNIYS

RIMS1

1051

Q86UR5
NSSHPTIVMFWKAFH

HERC5

931

Q9UII4
TMVAAYLIQVHKWSP

PTPMT1

141

Q8WUK0
LVESIWTYMPHVHIL

FBXO38

151

Q6PIJ6
PSLQAWSPEVHLYHM

PAPPA2

926

Q9BXP8
TWKILTIMPYNSAHH

KLHL14

351

Q9P2G3
KWSVHIAMHPQVNIY

FSCN1

131

Q16658
KQWHMIGHLQPETSY

CDON

886

Q4KMG0
MSWHPQYRSSKFRHV

CORO2A

1

Q92828
TSHVLSAYHMWTPRP

FSCN3

126

Q9NQT6
WYHDMENPKSHLIIA

BTD

321

P43251
SMHIYALHRNSAVWP

CYP4B1

406

P13584
STWVFPTLGIMHHNK

EEF1G

111

P26641
SYPIAEKTSMHSLWA

FAM186A

2301

A6NE01
WISPANSHCIKMLVY

GPR139

326

Q6DWJ6
PTTMLPRSAYWHHIT

DOK4

261

Q8TEW6
WGSLTHHINNMKPSF

MT-ND4

416

P03905
HANTHYWTGKMINPS

ERVW-1

81

Q9UQF0
KTLSYLHWIFQISHM

TMEM217B

116

A0A494BZU4
QLWTYESHKISMPLH

SLC25A40

266

Q8TBP6
SLAVVLMHSYTWAQH

OPLAH

186

O14841
QVPSKVIWDHLSTMY

MRGBP

71

Q9NV56
HIHLWISYIHLMSPF

PIGQ

351

Q9BRB3
NPNSLHHVKTMWYPE

RHOBTB2

111

Q9BYZ6
HKHELLTMYHGWVLT

SLC40A1

116

Q9NP59
NHHWRSYKLMIDPAL

SETD1B

26

Q9UPS6
HNLYGWSQMKPTHDA

SI

1456

P14410
HKVYTRHMTWIPLGN

POLR1C

166

O15160
SYAHTVKATMPIWVV

SLC35E1

136

Q96K37
HAHFWTTKAFLPTML

RDH10

171

Q8IZV5
LFAAMLLAWTHKHPN

PDXK

236

O00764
HGLLANPHSIYSEMW

ABCB7

691

O75027
KLIATTAHERMPWYH

ZAP70

151

P43403
SFKPHLMDVVYTWAT

MTREX

961

P42285
SGWKSMVVSHPHLVA

SPOP

336

O43791
SSVIYHLMTQHWGLD

TRPM2

151

O94759
SWYHHANPILLLVMY

PIEZO2

331

Q9H5I5
TMNNPLSHYWISSSH

PLCG1

321

P19174
FKQLHTPTNWLIHSM

TAAR1

51

Q96RJ0
SYLMWHQQTHTGEKP

ZNF264

356

O43296
RWDYILESMPHTHIQ

TM9SF2

286

Q99805
SYWKNMLEAVHTIHQ

TTK

626

P33981
HQTVHTWKKPYMCSV

ZNF23

606

P17027
TTYVPWPLMLHNHTS

LCMT2

631

O60294
LYLHHAKWSQAAPMA

VEGFA

16

P15692
SYLMWHQQTHTGEKP

ZNF805

356

Q5CZA5
MFSSHLHTWIKVASL

KLHL35

366

Q6PF15
LHRYKMISEFTWPNH

MYO1D

636

O94832