Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF711 ZNF729 ZNF750 ZNF624 ZNF100 ZHX2 MGA ZNF569 ZNF614 ZNF329 ZNF551	9.29e-05	1412	41	11	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF711 ZNF729 ZNF750 ZNF624 ZNF100 MGA ZNF569 ZNF614 ZNF329 ZNF551	5.80e-04	1459	41	10	GO:0000977
Domain	Znf_C2H2	ZNF711 ZNF729 ZNF750 ZNF624 SORBS2 ZNF100 ZNF474 ZHX2 ZNF569 ZNF614 ZNF329 ZNF551	5.06e-08	805	39	12	IPR007087
Domain	ZINC_FINGER_C2H2_2	ZNF711 ZNF729 ZNF624 ZNF100 ZNF474 ZHX2 ZNF569 ZNF614 ZNF329 ZNF551	3.04e-06	775	39	10	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF711 ZNF729 ZNF624 ZNF100 ZNF474 ZHX2 ZNF569 ZNF614 ZNF329 ZNF551	3.11e-06	777	39	10	PS00028
Domain	Znf_C2H2-like	ZNF711 ZNF729 ZNF750 ZNF624 ZNF100 ZHX2 ZNF569 ZNF614 ZNF329 ZNF551	3.86e-06	796	39	10	IPR015880
Domain	ZnF_C2H2	ZNF711 ZNF729 ZNF750 ZNF624 ZNF100 ZHX2 ZNF569 ZNF614 ZNF329 ZNF551	4.41e-06	808	39	10	SM00355
Domain	zf-C2H2	ZNF711 ZNF729 ZNF624 ZNF100 ZHX2 ZNF569 ZNF614 ZNF329 ZNF551	9.87e-06	693	39	9	PF00096
Domain	zf-C2H2_6	ZNF729 ZNF624 ZNF100 ZNF569 ZNF329 ZNF551	4.40e-05	314	39	6	PF13912
Domain	-	ZNF711 ZNF729 ZNF624 ZNF100 ZNF569 ZNF614 ZNF329 ZNF551	6.63e-05	679	39	8	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZNF711 ZNF729 ZNF624 ZNF100 ZNF569 ZNF614 ZNF329 ZNF551	7.73e-05	694	39	8	IPR013087
Domain	KRAB	ZNF729 ZNF624 ZNF100 ZNF569 ZNF614 ZNF551	9.09e-05	358	39	6	PS50805
Domain	KRAB	ZNF729 ZNF624 ZNF100 ZNF569 ZNF614 ZNF551	9.09e-05	358	39	6	PF01352
Domain	KRAB	ZNF729 ZNF624 ZNF100 ZNF569 ZNF614 ZNF551	1.07e-04	369	39	6	SM00349
Domain	KRAB	ZNF729 ZNF624 ZNF100 ZNF569 ZNF614 ZNF551	1.09e-04	370	39	6	IPR001909
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF729 ZNF624 ZNF569	2.90e-05	49	42	3	9630514
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF624 ZNF100 ZNF569 ZNF614	6.80e-05	181	42	4	37372979
Pubmed	Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.	ZNF624 ZNF569	2.67e-04	20	42	2	2542606
Pubmed	Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.	ZNF624 ZNF569	2.67e-04	20	42	2	7479878
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	ZNF711 RSBN1 WDR36 MGA VIRMA ZNF329 ZNF551	5.44e-04	1203	42	7	29180619
Pubmed	A genome-wide association study of behavioral disinhibition.	GALNT10 ZHX2	6.06e-04	30	42	2	23942779
Pubmed	The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.	ZNF711 C5orf24 WDR36 MGA	8.26e-04	349	42	4	25665578
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	CASP8AP2 ZNF624 VIRMA	8.45e-04	153	42	3	10718198
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	ZNF711 RSBN1 C5orf24 WDR36 TIAL1 MGA	9.47e-04	954	42	6	36373674
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	RSBN1 WDR36 TIAL1 VIRMA	1.03e-03	370	42	4	22922362
Pubmed	Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.	HAUS6 MGA KMT5B	1.13e-03	169	42	3	31462741
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF711 ZNF729 ZNF624 ZNF100 ZNF474 ZHX2 ZNF569 ZNF614 ZNF329 ZNF551	2.73e-08	718	26	10	28
Disease	prostate carcinoma, breast carcinoma, ovarian carcinoma	TET2 CCDC88C	6.16e-04	27	40	2	EFO_0000305, EFO_0001075, EFO_0001663
Disease	renal agenesis, unilateral	TET2 C5orf24	3.12e-03	61	40	2	MONDO_0019636
Disease	hypertension, white matter hyperintensity measurement	CCDC88C ZNF474	3.22e-03	62	40	2	EFO_0000537, EFO_0005665
Disease	juvenile idiopathic arthritis	RSBN1 NPHP4	4.55e-03	74	40	2	EFO_0002609
Disease	Parkinson disease	C5orf24 TIAL1 FGD4	9.36e-03	321	40	3	MONDO_0005180

Protein segments in the cluster

Peptide	Gene	Start	Entry
SNLQTSTSFEPHFKK	FAM200B	41	P0CF97
HAFLQFHNSTPKEFK	CACNG3	286	O60359
FHNSTPKEFKESLHN	CACNG3	291	O60359
SHQPATHFKFEETKT	LINC00518	61	Q8N0U6
PHSKNEITFSHNSSK	CASP8AP2	391	Q9UKL3
KHFGSPQSSKHYQTV	KANSL1L	66	A0AUZ9
HLKTTAAHTQSFKQP	MGA	2366	Q8IWI9
PQHTKKFCFDAISHT	GALNT10	516	Q86SR1
RHFSKSDSFSHNNPV	KMT5B	111	Q4FZB7
QNSFKHPAGKTAASH	CCDC88C	1021	Q9P219
PHSFKLTQSKSVHSF	FGD4	706	Q96M96
PDTFFHNGKKSIAHN	GABRA5	131	P31644
GNFTFTHKKVKHENF	IL10RA	176	Q13651
SKINHEPTTFQKYHQ	LIPH	361	Q8WWY8
HETAHVPFKFQSFSA	NPHP4	1056	O75161
KFHKPLATFSFANHT	METTL21A	16	Q8WXB1
HTDGFQKPTHFIKSN	BCLAF3	596	A2AJT9
SSQQSKYSHTVNHKP	C5orf24	36	Q7Z6I8
NSSHHFVETFNIKPQ	HAUS6	146	Q7Z4H7
KPASHSKTDLFQFNA	CCDC168	3326	Q8NDH2
SKTIPAHFFQEKVSH	LGSN	101	Q5TDP6
NKSHIFTFTHNFSGP	ERMAP	376	Q96PL5
KTGTKFSNFIHEEHQ	RSBN1	351	Q5VWQ0
NPKDTAVSFLHFHND	SULT6B1	141	Q6IMI4
HVSNHFTTESNKIPF	TDRD6	686	O60522
ADHPFLFFIQHSKTN	SERPINB6	351	P35237
KSHSDNSPNAFKDAS	SORBS2	151	O94875
NPTAKAVSFHTKSAF	ZNF750	186	Q32MQ0
PSAKVFHTFSNSNRH	ZNF100	181	Q8IYN0
FNTHQRTHTGEKPFK	ZNF624	711	Q9P2J8
HSSSSKHIQAFFNAK	ZNF551	206	Q7Z340
PAANKTNYSHHSKSQ	MTFR2	251	Q6P444
SDHNSKFHPGEANFK	ZHX2	126	Q9Y6X8
NSSSHFVITPFKCNH	ZNF569	176	Q5MCW4
NKLQQTFHHSKEPTF	ZNF474	11	Q6S9Z5
TFHHSKEPTFLINQA	ZNF474	16	Q6S9Z5
LSKTHFPIVQNHDTF	ZNF614	116	Q8N883
FTTNKKVSFHNHLES	ZNF711	421	Q9Y462
LQFQKPSHQVHFSKT	TET2	651	Q6N021
PSSQKKDTSNHFHVF	TIAL1	86	Q01085
FLDTFKHPSAEQSSH	VIRMA	11	Q69YN4
ESVKSFNHFTSLGHQ	ZNF329	151	Q86UD4
FKGSSNFNAHKVIHT	ZNF729	301	A6NN14
SFSTVHEKFNKSLGH	WDR36	406	Q8NI36