Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of synapse-associated extracellular matrix	LAMB1 LAMB2	6.84e-05	3	96	2	GO:0150043
GeneOntologyBiologicalProcess	basement membrane assembly	LAMB1 LAMB2 LAMB3	1.78e-05	12	91	3	GO:0070831
GeneOntologyBiologicalProcess	extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration	SRGAP2C SRGAP2	1.93e-05	2	91	2	GO:0021816
GeneOntologyBiologicalProcess	cerebral cortex radially oriented cell migration	SRGAP2C LAMB1 SRGAP2 LHX6	3.49e-05	42	91	4	GO:0021799
GeneOntologyBiologicalProcess	forebrain development	SRGAP2C LAMB1 MECOM SEMA5A IKZF1 SRGAP2 LHX6 FYN ALK NOTCH3	5.91e-05	489	91	10	GO:0030900
GeneOntologyBiologicalProcess	cerebral cortex cell migration	SRGAP2C LAMB1 SRGAP2 LHX6	1.09e-04	56	91	4	GO:0021795
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	RFPL4B USP17L4 KLHDC1 UBE2O USP17L2 USP17L1 LMO7 ZMIZ2 MKRN1 USP17L3 GAN PRKN FYN BIRC6	1.30e-04	1009	91	14	GO:0070647
GeneOntologyCellularComponent	laminin complex	LAMB1 LAMB2 LAMB3	1.03e-05	10	94	3	GO:0043256
Domain	Laminin_EGF	NTNG1 LAMB1 LAMB2 LAMB3 PEAR1	8.36e-07	35	94	5	PF00053
Domain	EGF_Lam	NTNG1 LAMB1 LAMB2 LAMB3 PEAR1	8.36e-07	35	94	5	SM00180
Domain	Laminin_N	NTNG1 LAMB1 LAMB2 LAMB3	1.05e-06	16	94	4	IPR008211
Domain	LAMININ_NTER	NTNG1 LAMB1 LAMB2 LAMB3	1.05e-06	16	94	4	PS51117
Domain	Laminin_N	NTNG1 LAMB1 LAMB2 LAMB3	1.05e-06	16	94	4	PF00055
Domain	LamNT	NTNG1 LAMB1 LAMB2 LAMB3	1.05e-06	16	94	4	SM00136
Domain	Laminin_EGF	NTNG1 LAMB1 LAMB2 LAMB3 PEAR1	1.28e-06	38	94	5	IPR002049
Domain	EGF_LAM_2	NTNG1 LAMB1 LAMB2 LAMB3	1.49e-05	30	94	4	PS50027
Domain	EGF_LAM_1	NTNG1 LAMB1 LAMB2 LAMB3	1.49e-05	30	94	4	PS01248
Domain	DH-domain	RASGRF1 RASGRF2 MCF2L2 ALS2CL TIAM2	2.91e-05	71	94	5	IPR000219
Domain	-	RASGRF1 RASGRF2 MCF2L2 ALS2CL TIAM2	2.91e-05	71	94	5	1.20.900.10
Domain	EGF-like_CS	MALRD1 NTNG1 LAMB1 LAMB2 LAMB3 NOTCH3 PEAR1 SORL1	5.16e-05	261	94	8	IPR013032
Domain	EGF_2	MALRD1 NTNG1 LAMB1 LAMB2 LAMB3 NOTCH3 PEAR1 SORL1	5.74e-05	265	94	8	PS01186
Domain	srGAP2	SRGAP2C SRGAP2	7.49e-05	3	94	2	IPR030252
Domain	LAMININ_IVB	LAMB1 LAMB2	7.49e-05	3	94	2	PS51116
Domain	Laminin_IV_B	LAMB1 LAMB2	7.49e-05	3	94	2	IPR013015
Domain	Galactose-bd-like	CEP104 NTNG1 LAMB1 LAMB2 LAMB3	1.12e-04	94	94	5	IPR008979
Domain	EGF	MALRD1 NTNG1 LAMB1 LAMB2 NOTCH3 PEAR1 SORL1	1.85e-04	235	94	7	SM00181
Domain	EGF-like_dom	MALRD1 NTNG1 LAMB1 LAMB2 NOTCH3 PEAR1 SORL1	2.63e-04	249	94	7	IPR000742
Domain	DH_1	RASGRF1 RASGRF2 MCF2L2 TIAM2	2.86e-04	63	94	4	PS00741
Domain	EGF_1	MALRD1 NTNG1 LAMB1 LAMB2 LAMB3 NOTCH3 PEAR1	3.04e-04	255	94	7	PS00022
Domain	RhoGEF	RASGRF1 RASGRF2 MCF2L2 TIAM2	3.83e-04	68	94	4	SM00325
Domain	RhoGEF	RASGRF1 RASGRF2 MCF2L2 TIAM2	4.28e-04	70	94	4	PF00621
Domain	DH_2	RASGRF1 RASGRF2 MCF2L2 TIAM2	4.28e-04	70	94	4	PS50010
Domain	UCH	USP17L4 USP17L2 USP17L1 USP17L3	4.52e-04	71	94	4	PF00443
Domain	USP_2	USP17L4 USP17L2 USP17L1 USP17L3	4.52e-04	71	94	4	PS00973
Domain	USP_3	USP17L4 USP17L2 USP17L1 USP17L3	4.76e-04	72	94	4	PS50235
Domain	USP_dom	USP17L4 USP17L2 USP17L1 USP17L3	4.76e-04	72	94	4	IPR028889
Domain	Peptidase_C19_UCH	USP17L4 USP17L2 USP17L1 USP17L3	4.76e-04	72	94	4	IPR001394
Domain	Tyr_kinase_rcpt_2_CS	INSRR ALK	1.34e-03	11	94	2	IPR002011
Domain	RECEPTOR_TYR_KIN_II	INSRR ALK	1.60e-03	12	94	2	PS00239
Domain	-	MALRD1 ALK SORL1	1.60e-03	46	94	3	4.10.400.10
Domain	LDLRA_1	MALRD1 ALK SORL1	1.81e-03	48	94	3	PS01209
Domain	LDLRA_2	MALRD1 ALK SORL1	1.92e-03	49	94	3	PS50068
Domain	LDrepeatLR_classA_rpt	MALRD1 ALK SORL1	1.92e-03	49	94	3	IPR002172
Domain	LDLa	MALRD1 ALK SORL1	1.92e-03	49	94	3	SM00192
Domain	Ras_G-nucl-exch_fac_CS	RASGRF1 RASGRF2	2.19e-03	14	94	2	IPR019804
Domain	PH	RASGRF1 RASGRF2 CADPS DGKK MCF2L2 TIAM2	2.81e-03	278	94	6	SM00233
Domain	PH_DOMAIN	RASGRF1 RASGRF2 CADPS DGKK MCF2L2 TIAM2	2.86e-03	279	94	6	PS50003
Domain	HABP4_PAI-RBP1	USP17L2 USP17L3	2.87e-03	16	94	2	PF04774
Domain	HABP4_PAIRBP1-bd	USP17L2 USP17L3	2.87e-03	16	94	2	IPR006861
Domain	PH_domain	RASGRF1 RASGRF2 CADPS DGKK MCF2L2 TIAM2	2.91e-03	280	94	6	IPR001849
Domain	-	RASGRF1 RASGRF2 CADPS DGKK MCF2L2 SPRED1 TIAM2	3.59e-03	391	94	7	2.30.29.30
Domain	MAM	MALRD1 ALK	3.64e-03	18	94	2	PF00629
Domain	MAM_dom	MALRD1 ALK	3.64e-03	18	94	2	IPR000998
Domain	MAM_2	MALRD1 ALK	3.64e-03	18	94	2	PS50060
Domain	RasGEFN	RASGRF1 RASGRF2	4.49e-03	20	94	2	SM00229
Domain	USP_CS	USP17L2 USP17L1 USP17L3	4.49e-03	66	94	3	IPR018200
Domain	RasGEF_N	RASGRF1 RASGRF2	4.95e-03	21	94	2	PF00618
Domain	USP_1	USP17L4 USP17L2 USP17L3	5.30e-03	70	94	3	PS00972
Domain	FCH	SRGAP2C SRGAP2	5.42e-03	22	94	2	PF00611
Domain	Ras-like_Gua-exchang_fac_N	RASGRF1 RASGRF2	5.42e-03	22	94	2	IPR000651
Domain	RASGEF_NTER	RASGRF1 RASGRF2	5.42e-03	22	94	2	PS50212
Domain	FCH	SRGAP2C SRGAP2	5.42e-03	22	94	2	SM00055
Domain	ZINC_FINGER_C2H2_2	ZNF462 KLF8 ZNF142 ZNF789 ZNF165 MECOM PLAGL2 IKZF1 ZNF593 ZBTB1	5.57e-03	775	94	10	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF462 KLF8 ZNF142 ZNF789 ZNF165 MECOM PLAGL2 IKZF1 ZNF593 ZBTB1	5.67e-03	777	94	10	PS00028
Domain	PH_dom-like	RASGRF1 RASGRF2 CADPS DGKK MCF2L2 SPRED1 TIAM2	5.71e-03	426	94	7	IPR011993
Domain	FCH_dom	SRGAP2C SRGAP2	5.92e-03	23	94	2	IPR001060
Domain	PH	RASGRF1 RASGRF2 CADPS DGKK TIAM2	6.02e-03	229	94	5	PF00169
Domain	Znf_C2H2-like	ZNF462 KLF8 ZNF142 ZNF789 ZNF165 MECOM PLAGL2 IKZF1 ZNF593 ZBTB1	6.69e-03	796	94	10	IPR015880
Domain	EGF_3	MALRD1 NTNG1 NOTCH3 PEAR1 SORL1	6.70e-03	235	94	5	PS50026
Domain	F_BAR	SRGAP2C SRGAP2	6.97e-03	25	94	2	IPR031160
Domain	F_BAR	SRGAP2C SRGAP2	6.97e-03	25	94	2	PS51741
Domain	-	ZNF462 KLF8 ZNF142 ZNF789 ZNF165 MECOM PLAGL2 IKZF1 ZBTB1	7.17e-03	679	94	9	3.30.160.60
Domain	Znf_C2H2	ZNF462 KLF8 ZNF142 ZNF789 ZNF165 MECOM PLAGL2 IKZF1 ZNF593 ZBTB1	7.22e-03	805	94	10	IPR007087
Pathway	REACTOME_MAPK_FAMILY_SIGNALING_CASCADES	USP17L4 VWF USP17L2 USP17L1 RASGRF1 RASGRF2 MARK3 USP17L3 SPRED1 FYN	2.70e-06	318	68	10	MM15278
Pathway	PID_INTEGRIN4_PATHWAY	LAMB1 LAMB2 LAMB3	1.72e-05	11	68	3	M158
Pathway	REACTOME_RAS_PROCESSING	USP17L4 USP17L2 USP17L1 USP17L3	6.36e-05	45	68	4	MM15671
Pathway	WP_ALPHA_6_BETA_4_INTEGRIN_SIGNALING_PATHWAY	LAMB1 LAMB2 LAMB3 FYN	2.85e-04	66	68	4	MM15925
Pathway	WP_FOCAL_ADHESION	VWF RASGRF1 LAMB1 LAMB2 LAMB3 FYN	3.88e-04	199	68	6	M39402
Pathway	KEGG_FOCAL_ADHESION	VWF RASGRF1 LAMB1 LAMB2 LAMB3 FYN	3.88e-04	199	68	6	M7253
Pathway	REACTOME_MET_ACTIVATES_PTK2_SIGNALING	LAMB1 LAMB2 LAMB3	3.97e-04	30	68	3	M27772
Pathway	REACTOME_LAMININ_INTERACTIONS	LAMB1 LAMB2 LAMB3	3.97e-04	30	68	3	M27216
Pubmed	High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency.	USP17L4 USP17L2 USP17L1 USP17L3	1.13e-08	10	96	4	24207026
Pubmed	Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells.	USP17L4 USP17L2 USP17L1 USP17L3	2.65e-08	12	96	4	24695638
Pubmed	ES cell neural differentiation reveals a substantial number of novel ESTs.	USP17L4 USP17L2 USP17L1 USP17L3	5.34e-08	14	96	4	11793228
Pubmed	CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.	USP17L4 USP17L2 USP17L1 USP17L3	2.05e-07	19	96	4	28067227
Pubmed	DUB-1, a deubiquitinating enzyme with growth-suppressing activity.	USP17L4 USP17L2 USP17L1 USP17L3	3.15e-07	21	96	4	8622927
Pubmed	DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes.	USP17L4 USP17L2 USP17L1 USP17L3	3.15e-07	21	96	4	14583620
Pubmed	DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes.	USP17L4 USP17L2 USP17L1 USP17L3	3.15e-07	21	96	4	11468161
Pubmed	The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.	USP17L4 USP17L2 USP17L1 USP17L3	3.15e-07	21	96	4	8756639
Pubmed	Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines.	USP17L4 USP17L2 USP17L1 USP17L3	3.15e-07	21	96	4	12447969
Pubmed	DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway.	USP17L4 USP17L2 USP17L1 USP17L3	3.15e-07	21	96	4	18980247
Pubmed	JAK2 is required for induction of the murine DUB-1 gene.	USP17L4 USP17L2 USP17L1 USP17L3	3.84e-07	22	96	4	9154835
Pubmed	DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes.	USP17L4 USP17L2 USP17L1 USP17L3	5.55e-07	24	96	4	8995226
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	ZNF462 LMO7 ZMIZ2 MKRN1 PLAGL2 IKZF1 ZFAND5 ZNF593 BIRC6 ZBTB1 TOP3A CTDSP2	6.15e-07	709	96	12	22988430
Pubmed	Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production.	USP17L4 USP17L2 USP17L1 USP17L3	6.59e-07	25	96	4	21115691
Pubmed	Laminins promote the locomotion of skeletal myoblasts via the alpha 7 integrin receptor.	LAMB1 LAMB2 LAMB3	7.08e-07	7	96	3	9004048
Pubmed	Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice.	USP17L4 USP17L2 USP17L1 USP17L3	7.78e-07	26	96	4	35816173
Pubmed	Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion.	USP17L4 USP17L2 USP17L1 USP17L3	1.23e-06	29	96	4	32527007
Pubmed	Cdc25A and Dub3 in a high-stakes balancing act.	USP17L4 USP17L2 USP17L1 USP17L3	2.10e-06	33	96	4	20228807
Pubmed	The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.	USP17L4 USP17L2 USP17L1 USP17L3	2.37e-06	34	96	4	20403174
Pubmed	DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.	USP17L4 USP17L2 USP17L1 USP17L3	2.37e-06	34	96	4	14699124
Pubmed	The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence.	USP17L4 USP17L2 USP17L1 USP17L3	2.37e-06	34	96	4	15780755
Pubmed	USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.	USP17L4 USP17L2 USP17L1 USP17L3	2.37e-06	34	96	4	19188362
Pubmed	Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene.	USP17L4 USP17L2 USP17L1 USP17L3	2.37e-06	34	96	4	11941478
Pubmed	Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability.	USP17L4 USP17L2 USP17L1 USP17L3	2.37e-06	34	96	4	17109758
Pubmed	The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.	USP17L4 USP17L2 USP17L1 USP17L3	2.37e-06	34	96	4	20388806
Pubmed	Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme.	USP17L4 USP17L2 USP17L1 USP17L3	2.37e-06	34	96	4	20715989
Pubmed	Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation.	USP17L4 USP17L2 USP17L1 USP17L3	2.37e-06	34	96	4	9806828
Pubmed	The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling.	USP17L4 USP17L2 USP17L1 USP17L3	2.37e-06	34	96	4	20368735
Pubmed	The RS447 human megasatellite tandem repetitive sequence encodes a novel deubiquitinating enzyme with a functional promoter.	USP17L4 USP17L2 USP17L1 USP17L3	2.37e-06	34	96	4	10936051
Pubmed	The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.	USP17L4 USP17L2 USP17L1 USP17L3	2.37e-06	34	96	4	21448158
Pubmed	Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.	LAMB1 LAMB2 LAMB3	2.41e-06	10	96	3	9034910
Pubmed	Cytokine-regulated protein degradation by the ubiquitination system.	USP17L4 USP17L2 USP17L1 USP17L3	2.67e-06	35	96	4	16611142
Pubmed	Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity.	USP17L4 USP17L2 USP17L1 USP17L3	2.67e-06	35	96	4	21239494
Pubmed	The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.	USP17L4 USP17L2 USP17L1 USP17L3	3.00e-06	36	96	4	20147298
Pubmed	Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin.	PODXL LAMB1 LAMB2	3.31e-06	11	96	3	11435469
Pubmed	Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.	LAMB1 LAMB2 LAMB3	3.31e-06	11	96	3	23472759
Pubmed	Regional differences in the expression of laminin isoforms during mouse neural tube development.	LAMB1 LAMB2 LAMB3	3.31e-06	11	96	3	21524702
Pubmed	Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.	USP17L4 USP17L2 USP17L1 USP17L3	3.36e-06	37	96	4	20228808
Pubmed	Muscle progenitor cells failing to respond to positional cues adopt non-myogenic fates in myf-5 null mice.	LAMB1 LAMB2 LAMB3	4.40e-06	12	96	3	8918877
Pubmed	Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.	LAMB1 LAMB2 LAMB3	4.40e-06	12	96	3	9396756
Pubmed	RASGRF2 controls nuclear migration in postnatal retinal cone photoreceptors.	RASGRF1 RASGRF2	7.54e-06	2	96	2	26743081
Pubmed	Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation and long-term depression.	RASGRF1 RASGRF2	7.54e-06	2	96	2	16467520
Pubmed	Deletions of IKZF1 and SPRED1 are associated with poor prognosis in a population-based series of pediatric B-cell precursor acute lymphoblastic leukemia diagnosed between 1992 and 2011.	SPRED1 IKZF1	7.54e-06	2	96	2	23823658
Pubmed	SRGAP2 and Its Human-Specific Paralog Co-Regulate the Development of Excitatory and Inhibitory Synapses.	SRGAP2C SRGAP2	7.54e-06	2	96	2	27373832
Pubmed	The environment versus genetics in controlling the contribution of MAP kinases to synaptic plasticity.	RASGRF1 RASGRF2	7.54e-06	2	96	2	17141611
Pubmed	The C-terminal region of laminin beta chains modulates the integrin binding affinities of laminins.	LAMB1 LAMB2	7.54e-06	2	96	2	19147489
Pubmed	Endothelial von Willebrand factor release due to eNOS deficiency predisposes to thrombotic microangiopathy in mouse aging kidney.	VWF NOS3	7.54e-06	2	96	2	20363914
Pubmed	Transgenerational rescue of a genetic defect in long-term potentiation and memory formation by juvenile enrichment.	RASGRF1 RASGRF2	7.54e-06	2	96	2	19193896
Pubmed	Activation of H-Ras in the endoplasmic reticulum by the RasGRF family guanine nucleotide exchange factors.	RASGRF1 RASGRF2	7.54e-06	2	96	2	14749369
Pubmed	Forced expression of laminin beta1 in podocytes prevents nephrotic syndrome in mice lacking laminin beta2, a model for Pierson syndrome.	LAMB1 LAMB2	7.54e-06	2	96	2	21876163
Pubmed	A murine CDC25/ras-GRF-related protein implicated in Ras regulation.	RASGRF1 RASGRF2	7.54e-06	2	96	2	8293576
Pubmed	Ras-GRF2 regulates nestin-positive stem cell density and onset of differentiation during adult neurogenesis in the mouse dentate gyrus.	RASGRF1 RASGRF2	7.54e-06	2	96	2	28966131
Pubmed	The Inhibition of RasGRF2, But Not RasGRF1, Alters Cocaine Reward in Mice.	RASGRF1 RASGRF2	7.54e-06	2	96	2	31182637
Pubmed	Switch in Laminin β2 to Laminin β1 Isoforms During Aging Controls Endothelial Cell Functions-Brief Report.	LAMB1 LAMB2	7.54e-06	2	96	2	29599141
Pubmed	Basement membrane composition in the early mouse embryo day 7.	LAMB1 LAMB2 LAMB3	9.05e-06	15	96	3	15895400
Pubmed	Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.	LAMB1 LAMB2 LAMB3	1.11e-05	16	96	3	17601529
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	USP17L4 USP17L2 USP17L1 USP17L3	1.14e-05	50	96	4	31806660
Pubmed	TGF-beta-1 up-regulates extra-cellular matrix production in mouse hepatoblasts.	LAMB1 LAMB2 LAMB3	1.61e-05	18	96	3	23041440
Pubmed	Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.	LAMB1 LAMB2 LAMB3	1.61e-05	18	96	3	11311202
Pubmed	Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.	LAMB1 LAMB2 LAMB3	2.25e-05	20	96	3	22911573
Pubmed	Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation.	SRGAP2C SRGAP2	2.26e-05	3	96	2	22559944
Pubmed	RasGRF suppresses Cdc42-mediated tumour cell movement, cytoskeletal dynamics and transformation.	RASGRF1 RASGRF2	2.26e-05	3	96	2	21685891
Pubmed	Increased renal oxidative stress in salt-sensitive human GRK4γ486V transgenic mice.	GRK4 NOS3	2.26e-05	3	96	2	28189851
Pubmed	Identification of mutations in the gene encoding lamins A/C in autosomal dominant limb girdle muscular dystrophy with atrioventricular conduction disturbances (LGMD1B).	LAMB1 LAMB2	2.26e-05	3	96	2	10814726
Pubmed	Comparative study on the histomorphology and molecular biology of radial artery conduits in patients with diabetes mellitus who underwent coronary bypass surgery.	VWF NOS3	2.26e-05	3	96	2	22972845
Pubmed	Targeted disruption of Ras-Grf2 shows its dispensability for mouse growth and development.	RASGRF1 RASGRF2	2.26e-05	3	96	2	11909944
Pubmed	CAPS1 deficiency perturbs dense-core vesicle trafficking and Golgi structure and reduces presynaptic release probability in the mouse brain.	CADPS PTF1A	2.26e-05	3	96	2	24174665
Pubmed	Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB.	RASGRF1 RASGRF2	2.26e-05	3	96	2	15029245
Pubmed	Sequencing of laminin B chain cDNAs reveals C-terminal regions of coiled-coil alpha-helix.	LAMB1 LAMB2	2.26e-05	3	96	2	6209134
Pubmed	A strategy for cloning the hereditary hemochromatosis gene.	ZNF165 CTDSP2	2.26e-05	3	96	2	8673473
Pubmed	Neither replication nor simulation supports a role for the axon guidance pathway in the genetics of Parkinson's disease.	NTNG1 SEMA5A FYN	3.02e-05	22	96	3	18628988
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	SUPT20H LMO7 CTR9 DHX40 MECOM ZNF593 TOP3A STAT2 SORL1	3.73e-05	588	96	9	38580884
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ZNF462 LMO7 CADPS SMG5 BIRC6 UNC80	3.91e-05	225	96	6	12168954
Pubmed	Evolution of human-specific neural SRGAP2 genes by incomplete segmental duplication.	SRGAP2C SRGAP2	4.51e-05	4	96	2	22559943
Pubmed	Structural and spatial determinants regulating TC21 activation by RasGRF family nucleotide exchange factors.	RASGRF1 RASGRF2	4.51e-05	4	96	2	19692568
Pubmed	Developmental expression of nicein adhesion protein (laminin-5) subunits suggests multiple morphogenic roles.	LAMB2 LAMB3	4.51e-05	4	96	2	8081888
Pubmed	Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits.	LAMB1 LAMB2	4.51e-05	4	96	2	2099832
Pubmed	Role of mesenchymal nidogen for epithelial morphogenesis in vitro.	LAMB1 LAMB2	4.51e-05	4	96	2	7925005
Pubmed	RasGRF Couples Nox4-Dependent Endoplasmic Reticulum Signaling to Ras.	RASGRF1 RASGRF2	4.51e-05	4	96	2	27856453
Pubmed	Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL.	IKZF1 NOTCH3	4.51e-05	4	96	2	20829372
Pubmed	Ras-guanine-nucleotide-releasing factors 1 and 2 interact with PLCγ at focal adhesions to enable IL-1-induced Ca(2+) signalling, ERK activation and MMP-3 expression.	RASGRF1 RASGRF2	4.51e-05	4	96	2	23145787
Pubmed	ZnT-3, a putative transporter of zinc into synaptic vesicles.	SLC30A3 NOS3	4.51e-05	4	96	2	8962159
Pubmed	Laminins 411 and 421 differentially promote tumor cell migration via α6β1 integrin and MCAM (CD146).	LAMB1 LAMB2	4.51e-05	4	96	2	24951930
Pubmed	Regulation and Function of Laminin A5 during Mouse and Human Decidualization.	LAMB1 LAMB2	4.51e-05	4	96	2	35008625
Pubmed	Changes in laminin isoforms associated with brain tumor invasion and angiogenesis.	LAMB1 LAMB2	4.51e-05	4	96	2	16146715
Pubmed	Laminin chain assembly. Specific sequences at the C terminus of the long arm are required for the formation of specific double- and triple-stranded coiled-coil structures.	LAMB1 LAMB2	4.51e-05	4	96	2	8034675
Pubmed	Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.	LAMB1 LAMB2 LAMB3	5.06e-05	26	96	3	24742657
Pubmed	Dlx5 and Dlx6 regulate the development of parvalbumin-expressing cortical interneurons.	IKZF1 LHX6 TIAM2	6.35e-05	28	96	3	20392955
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	INHBE VWF LAMB1 LAMB2 LAMB3	6.83e-05	153	96	5	25037231
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	LAMB1 LAMB2 LAMB3	7.07e-05	29	96	3	22613833
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	ZNF462 VWF RASGRF2 MKRN1 SPRED1 BIRC6 MED13 NOTCH3	7.26e-05	497	96	8	23414517
Pubmed	Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway.	VWF FYN	7.50e-05	5	96	2	18550847
Pubmed	Association of the ACE, GSTM1, IL-6, NOS3, and CYP1A1 polymorphisms with susceptibility of mycoplasma pneumoniae pneumonia in Chinese children.	CYP1A1 NOS3	7.50e-05	5	96	2	28403117
Pubmed	Posttranslational modifications and beta/gamma chain associations of human laminin alpha1 and laminin alpha5 chains: purification of laminin-3 from placenta.	LAMB1 LAMB2	7.50e-05	5	96	2	10964500
Pubmed	Laminin-10 is crucial for hair morphogenesis.	LAMB1 LAMB2	7.50e-05	5	96	2	12743034
Pubmed	Human and mouse proteases: a comparative genomic approach.	USP17L4 USP17L2 USP17L1 USP17L3	7.71e-05	81	96	4	12838346
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	GRK4 INSRR GAN PRKN FYN ALK STAT2	7.98e-05	372	96	7	22939624
Pubmed	Functional analysis of secreted and transmembrane proteins critical to mouse development.	LAMB1 BIRC6 NOTCH3	8.66e-05	31	96	3	11431694
Pubmed	Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TMEM104 ZSWIM4 ALS2CL PEAR1	9.30e-05	85	96	4	15449545
Pubmed	Cross-linking of laminin-nidogen complexes by tissue transglutaminase. A novel mechanism for basement membrane stabilization.	LAMB1 LAMB2	1.12e-04	6	96	2	1678389
Interaction	ZKSCAN1 interactions	RFPL4B KLF8 UBE2O PGBD1 PRKN TNFRSF19	5.24e-07	66	91	6	int:ZKSCAN1
GeneFamily	Laminin subunits	LAMB1 LAMB2 LAMB3	1.24e-05	12	71	3	626
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASGRF1 RASGRF2 MCF2L2 TIAM2	1.31e-04	66	71	4	722
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF462 KLF8 ZNF142 ZNF789 ZNF165 MECOM PLAGL2 IKZF1 ZBTB1	1.92e-03	718	71	9	28
Coexpression	GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN	USP17L4 USP17L2 USP17L1 INSRR USP17L3 PLAGL2	3.61e-06	112	96	6	MM1095
Coexpression	LAKE_ADULT_KIDNEY_C2_PODOCYTES	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	1.33e-05	212	96	7	M39221
Coexpression	NABA_BASEMENT_MEMBRANES	NTNG1 LAMB1 LAMB2 LAMB3	1.40e-05	40	96	4	M5887
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	8.05e-08	168	96	7	fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	8.05e-08	168	96	7	315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	8.05e-08	168	96	7	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	facs-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1A1 KLF8 VWF PGBD1 LAMB2 ZSWIM4 LHX6	8.73e-08	170	96	7	8e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCell	facs-Lung-nan-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1A1 KLF8 VWF PGBD1 LAMB2 ZSWIM4 LHX6	8.73e-08	170	96	7	67d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	9.45e-08	172	96	7	6c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	9.45e-08	172	96	7	381ae1c3c07d0a424f43455ec571653b192a946a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	1.02e-07	174	96	7	dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	1.15e-07	177	96	7	4d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	1.19e-07	178	96	7	edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	1.24e-07	179	96	7	7394e77e665bf16d3733df91bb12907be460ab44
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	1.34e-07	181	96	7	5bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	1.34e-07	181	96	7	8e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCell	COVID-19-kidney-Podocyte\|kidney / Disease (COVID-19 only), tissue and cell type	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	1.44e-07	183	96	7	fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	1.44e-07	183	96	7	3c516fe5083f02bad1f464ed284010b4131a833c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	1.44e-07	183	96	7	612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	1.44e-07	183	96	7	848fc6dd129150897ee339343e83c645b6e779eb
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	1.44e-07	183	96	7	eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	1.44e-07	183	96	7	9c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	1.44e-07	183	96	7	7c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	1.50e-07	184	96	7	7294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	1.55e-07	185	96	7	9197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	1.55e-07	185	96	7	ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL FYN	1.55e-07	185	96	7	b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF RASGRF2 PODXL HRCT1 MECOM LHX6 NOS3	1.80e-07	189	96	7	8ced0381ea042ba47680a02b617a2368fa2c54c8
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF RASGRF2 PODXL HRCT1 MECOM LHX6 NOS3	1.80e-07	189	96	7	403a82bb416aed13b9d31411ad17bdc4ce2a95fb
ToppCell	facs-MAT-Fat-24m-Endothelial-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1A1 VWF RASGRF2 LMO7 PODXL HRCT1 NOS3	2.07e-07	193	96	7	ba9a47e2dc01efa6d2a99b1631d4951fac2648d4
ToppCell	facs-MAT-Fat-24m-Endothelial-endothelial_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1A1 VWF RASGRF2 LMO7 PODXL HRCT1 NOS3	2.07e-07	193	96	7	724bb613fa434add5b1c5586b629328f819fbdfe
ToppCell	facs-MAT-Fat-24m-Endothelial\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1A1 VWF RASGRF2 LMO7 PODXL HRCT1 NOS3	2.07e-07	193	96	7	737e540c72a3cfe8dbd4c0f139f7d729a166793a
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INHBE VWF PODXL LAMB2 MECOM NOS3	1.22e-06	158	96	6	ba9998cbf786c515d30fe42de02c7a246db1b6f9
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INHBE VWF PODXL LAMB2 MECOM NOS3	1.22e-06	158	96	6	a2efcc184ef13d81373e3690253ba35f6be09c5f
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INHBE VWF PODXL LAMB2 MECOM NOS3	1.22e-06	158	96	6	e52eff2bd1e7e0ce9c278ed5109802865e0fe69c
ToppCell	COVID-19-kidney-Podocyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL	2.20e-06	175	96	6	a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL	2.59e-06	180	96	6	d685fa2b013bc085dbef7c40956ed3043f83e483
ToppCell	COVID-19-Heart-EC_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	VWF RASGRF2 PODXL MECOM LHX6 NOS3	2.85e-06	183	96	6	ff95382cfed592190d0636d2b750328471f82e0d
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	CYP1A1 VWF RASGRF2 PODXL MECOM NOS3	2.95e-06	184	96	6	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF RASGRF2 LMO7 LAMB2 MECOM NOS3	3.13e-06	186	96	6	9c7924875f70420720149287c500b4dfa8d24673
ToppCell	droplet-Lung-LUNG-1m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF RASGRF2 LMO7 DGKK MECOM NOS3	3.13e-06	186	96	6	1e67bfb248366d7395efdd2d5e70a97bdb2e68af
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF RASGRF2 DGKK LAMB2 MECOM NOS3	3.13e-06	186	96	6	ffbc78058be8f0dc2e0335cc4c3195a636d17721
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF RASGRF2 DGKK LAMB2 MECOM NOS3	3.13e-06	186	96	6	ed924852cd7132c8f6703522037dc22bd2c83193
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL	3.23e-06	187	96	6	24c2a3962da364e46e98abeab5f8234376fa26bb
ToppCell	Endothelial-A-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	VWF RASGRF2 PODXL HRCT1 LHX6 NOS3	3.23e-06	187	96	6	febe0b99a6a815ce687160a0e7af55228b1d5beb
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF RASGRF2 PODXL HRCT1 MECOM NOS3	3.33e-06	188	96	6	05de6677f9bb4b00fed47f4b72f4a2cd507cb0f2
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL	3.33e-06	188	96	6	9db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL	3.33e-06	188	96	6	047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCell	COVID-19-Heart-EC_3\|Heart / Disease (COVID-19 only), tissue and cell type	VWF RASGRF2 PODXL MECOM LHX6 NOS3	3.54e-06	190	96	6	78e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Artery\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF PODXL MECOM TNFRSF19 NOS3 TIAM2	3.65e-06	191	96	6	4b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF RASGRF2 PODXL MECOM LHX6 NOS3	3.76e-06	192	96	6	945153c41dde6e90d103206955e1707b54eb0665
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF RASGRF2 PODXL MECOM LHX6 NOS3	3.76e-06	192	96	6	6ab50579c63f31ca2cd41063a99b129f11c07510
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A SRGAP2 ALS2CL	3.88e-06	193	96	6	3eaa0461618582a1754400624350d269d24e750a
ToppCell	facs-MAT-Fat-3m-Endothelial\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1A1 VWF PODXL MECOM LHX6 NOS3	3.88e-06	193	96	6	b32533afeff1905e188becaa09079e9699722e4b
ToppCell	facs-MAT-Fat-3m-Endothelial-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1A1 VWF PODXL MECOM LHX6 NOS3	3.88e-06	193	96	6	2ff573ba2c74583ed1cb071a3bbc01bb71117e5f
ToppCell	facs-MAT-Fat-3m-Endothelial-endothelial_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1A1 VWF PODXL MECOM LHX6 NOS3	3.88e-06	193	96	6	e164f6403a8b541ced08a6feec915d2e855036ea
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	VWF RASGRF2 PODXL FYN NOS3 DUSP11	4.11e-06	195	96	6	6bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCell	LA-09._Endothelium_I\|World / Chamber and Cluster_Paper	VWF RASGRF2 PODXL MECOM LHX6 NOS3	4.11e-06	195	96	6	fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VWF PODXL LAMB1 MECOM LHX6 NOS3	4.11e-06	195	96	6	4658fb197657d7692ee344ae76b11b0210c418ba
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF RASGRF2 PODXL MECOM LHX6 NOS3	4.11e-06	195	96	6	4db30b3bc65c25626f828cd4f867f20c71809898
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF PODXL MECOM LHX6 SLC30A3 NOS3	4.24e-06	196	96	6	9b53e3fdb23dbdfc2e7ce012c6b2ce50700c95d5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	VWF RASGRF2 PODXL LHX6 FYN NOS3	4.24e-06	196	96	6	ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VWF PODXL HRCT1 MECOM LHX6 PEAR1	4.36e-06	197	96	6	9e948b2e0f7e426f1e6f95bbbf4282fbddc2b99d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	VWF RASGRF2 PODXL LHX6 FYN NOS3	4.36e-06	197	96	6	412cb5f37df57121ddd1492021445479c7cbccbf
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VWF PODXL LAMB1 MECOM NOS3 PEAR1	4.49e-06	198	96	6	72e8b9cccb7b0a2ea9d415218fff4fa2f09728f4
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VWF PODXL LAMB1 MECOM NOS3 PEAR1	4.49e-06	198	96	6	e1fa02184ce93c4f8aa5cf04b70949cd4c425ff0
ToppCell	moderate-Epithelial-Secretory\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	LMO7 PODXL MECOM GAN ANKRD36C TSPAN3	4.49e-06	198	96	6	7d96d7105a849c7280ce87bd76ce130ac47384fd
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VWF PODXL LAMB1 MECOM NOS3 PEAR1	4.62e-06	199	96	6	9c40b3ee39860e9d8edafd007daec11abdd95435
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VWF PODXL LAMB1 MECOM NOS3 PEAR1	4.62e-06	199	96	6	72b34bce8157abe389e95cd3ed8ba578dce0cbf6
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VWF PODXL LAMB1 MECOM NOS3 PEAR1	4.62e-06	199	96	6	0602e2b2aa56d106da63bd342a38bef437b4d496
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VWF PODXL LAMB1 MECOM NOS3 PEAR1	4.62e-06	199	96	6	463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Artery\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	CYP1A1 VWF RASGRF2 PODXL MECOM NOS3	4.76e-06	200	96	6	34b279804475ea58fbb052b96f44128c082627a9
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Artery\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CYP1A1 VWF RASGRF2 PODXL MECOM NOS3	4.76e-06	200	96	6	8552cc7a439449b30b59760c3e8667217b9852b5
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Artery-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYP1A1 VWF RASGRF2 PODXL MECOM NOS3	4.76e-06	200	96	6	45c08f1befe78553bbadcc2fcffb6138306638f3
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Interneuron\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	GAN IKZF1 LHX6 NOS3 UNC80	6.51e-06	121	96	5	b2d571f571133c281d72584fe925cebbd2317829
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Interneuron\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	KLHDC1 PIK3C2G LHX6 ALK TOP3A	7.93e-06	126	96	5	ec445ec097c9c45cd47b8cfa8c140df5b298695e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SRGAP2 ALS2CL	2.16e-05	155	96	5	90e629681a72baacc7981b82883866a487638dbc
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SRGAP2 ALS2CL	2.16e-05	155	96	5	e7f49e2fdaf184fa6b4e685518004e7deff1316d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SRGAP2 ALS2CL	2.16e-05	155	96	5	5a872ca70ae8c30b57f45a6772d7bf565e0c2663
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_STALK\|Thalamus / BrainAtlas - Mouse McCarroll V32	VWF PODXL MECOM NOS3 IL27RA	2.16e-05	155	96	5	fe6c4aba0e98cda84bf178aeac2e9fa834477f22
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	VWF RASGRF2 PODXL PGBD1 LHX6	2.75e-05	163	96	5	977a970b1296234c22178420294cea73506ee02f
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	VWF RASGRF2 HRCT1 PGBD1 LHX6	2.75e-05	163	96	5	ba7d02db0f0e2f9916ec8db52c067c87b6917c23
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D122\|Adult / Lineage, Cell type, age group and donor	VWF RASGRF2 PODXL NOS3 PEAR1	3.18e-05	168	96	5	8c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A ALS2CL	3.36e-05	170	96	5	60bbd738c12e64e483485586c30057304884f5a6
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF RASGRF2 MECOM LHX6 NOS3	3.76e-05	174	96	5	fa6eb451555766398996bbe8f555a3f4c0f3c108
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF RASGRF2 MECOM LHX6 NOS3	3.76e-05	174	96	5	1f5b0fa58b2a7335667357af7e50e5242cd13d7d
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF RASGRF2 MECOM LHX6 NOS3	3.76e-05	174	96	5	ac3aee6ed49d1c421f33509e3ffc5cb17750a473
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NTNG1 ANKRD62 LAMB1 SLC30A3 ALS2CL	4.19e-05	178	96	5	674ee5095b98929c29e4f6bd56029a336cc4a38c
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF RASGRF2 LMO7 MECOM NOS3	4.30e-05	179	96	5	a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCell	facs-Heart-RV-24m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1A1 RASGRF2 PODXL HRCT1 NOS3	4.30e-05	179	96	5	6aa211670e5d6e013d0980967aa0a4f8f2905efe
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A ALS2CL	4.30e-05	179	96	5	c1c0b7186a0eab8c76404b95f1cf8d64b1b45cb1
ToppCell	facs-Heart-RV-24m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1A1 RASGRF2 PODXL HRCT1 NOS3	4.30e-05	179	96	5	cf4d3828a3ce97932c68d06f5c65a070fc6d832c
ToppCell	AT1_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	LMO7 HRCT1 LAMB2 SEMA5A ALS2CL	4.30e-05	179	96	5	1603117b52623663458a977c94bf7f9f6c1114b8
ToppCell	facs-Heart-RV-24m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP1A1 RASGRF2 PODXL HRCT1 NOS3	4.30e-05	179	96	5	f9bc76ff25f88ee44c72499a0df9dc16f519c4cb
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	VWF RASGRF2 PODXL MECOM NOS3	4.30e-05	179	96	5	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NTNG1 ANKRD62 LAMB1 SLC30A3 ALS2CL	4.41e-05	180	96	5	fd8c2059fcb382ffbfe19e598e37a49e1d5637b5
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_RORB_CARTPT\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PIK3C2G PODXL NTNG1 LAMB1 GPRC6A	4.41e-05	180	96	5	5e78b29fa1cbdcf502fee3577e5b45766b90d1dc
ToppCell	AT1_cells-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	LMO7 LAMB2 LAMB3 SEMA5A ALS2CL	4.41e-05	180	96	5	2d52cb5f77dde0e3dccac1333d4ec67ec680fcb2
ToppCell	facs-Lung-18m-Mesenchymal-myofibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HRCT1 LAMB1 TNFRSF19 GPRC6A NOTCH3	4.53e-05	181	96	5	dff264815a3569f5666d0bbc3867c0496cd78774
ToppCell	COVID-19-Heart-EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	VWF RASGRF2 MECOM SEMA5A NOTCH3	4.65e-05	182	96	5	e67f3234165199085c793915ebb1f9bbd845e933
ToppCell	droplet-Liver-Npc-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PODXL MECOM FYN NOS3 PEAR1	4.65e-05	182	96	5	dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C PODXL NTNG1 SEMA5A ALS2CL	4.65e-05	182	96	5	cde8fa4f42d25545abaa9ee885b4b1e24a5a8e08
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF RASGRF2 LAMB2 MECOM NOS3	4.65e-05	182	96	5	c7f2d24697affa530b748ab32b1d40bdc1bdc20a
Disease	primary ovarian insufficiency (implicated_via_orthology)	USP17L4 USP17L2 USP17L1 USP17L3	1.42e-05	46	94	4	DOID:5426 (implicated_via_orthology)
Disease	congenital heart disease (implicated_via_orthology)	USP17L4 USP17L2 USP17L1 USP17L3	7.12e-05	69	94	4	DOID:1682 (implicated_via_orthology)
Disease	platelet component distribution width	CYP1A1 UBE2O VWF SUPT20H MARK3 MECOM IKZF1 NOS3 CTDSP2 PEAR1	1.48e-04	755	94	10	EFO_0007984
Disease	Malignant neoplasm of breast	CYP1A1 INHBE VWF GFRAL RASGRF2 MCF2L2 MECOM ALS2CL ALK NOS3 NOTCH3 SORL1	1.56e-04	1074	94	12	C0006142
Disease	androsterone sulfate measurement	ZNF789 BIRC6 ALK	1.59e-04	33	94	3	EFO_0021117
Disease	Behcet's disease (is_implicated_in)	CYP1A1 VWF NOS3	2.07e-04	36	94	3	DOID:13241 (is_implicated_in)
Disease	Autistic behavior	ZNF462 MED13	2.78e-04	8	94	2	C0856975
Disease	end stage renal disease (is_implicated_in)	CYP1A1 VWF NOS3	3.06e-04	41	94	3	DOID:783 (is_implicated_in)
Disease	Cancer of Nasopharynx	MECOM TNFRSF19	3.56e-04	9	94	2	C0238301
Disease	Nasopharyngeal Neoplasms	MECOM TNFRSF19	3.56e-04	9	94	2	C0027439
Disease	diffuse scleroderma	ZNF789 DDX6	3.56e-04	9	94	2	EFO_0000404
Disease	coffee consumption measurement, insomnia	SUPT20H PODXL	4.44e-04	10	94	2	EFO_0004698, EFO_0006781
Disease	Intellectual Disability	ZNF462 KLF8 ZNF142 PEX11B FHIP2A MED13 DDX6	5.76e-04	447	94	7	C3714756
Disease	acute lymphoblastic leukemia (is_implicated_in)	CYP1A1 IKZF1 NOS3	7.28e-04	55	94	3	DOID:9952 (is_implicated_in)
Disease	Global developmental delay	ZNF462 ZNF142 FHIP2A DDX6	8.79e-04	133	94	4	C0557874
Disease	Impaired cognition	NOTCH3 SORL1	8.91e-04	14	94	2	C0338656
Disease	essential hypertension (is_implicated_in)	GRK4 NOS3	1.49e-03	18	94	2	DOID:10825 (is_implicated_in)
Disease	age at onset, Parkinson disease	KLHDC1 PRKN	1.49e-03	18	94	2	EFO_0004847, MONDO_0005180
Disease	Paroxysmal atrial fibrillation	ZNF462 VWF NOS3 SORL1	1.58e-03	156	94	4	C0235480
Disease	familial atrial fibrillation	ZNF462 VWF NOS3 SORL1	1.58e-03	156	94	4	C3468561
Disease	Persistent atrial fibrillation	ZNF462 VWF NOS3 SORL1	1.58e-03	156	94	4	C2585653
Disease	Alcoholic Intoxication, Chronic	VWF RASGRF2 SEMA5A FYN ALK	1.69e-03	268	94	5	C0001973
Disease	Atrial Fibrillation	ZNF462 VWF NOS3 SORL1	1.74e-03	160	94	4	C0004238
Disease	response to peginterferon alfa-2a	VWF PRKN	2.87e-03	25	94	2	EFO_0010103
Disease	epiandrosterone sulfate measurement	ZNF789 ALK	2.87e-03	25	94	2	EFO_0021120

Protein segments in the cluster

Peptide	Gene	Start	Entry
RAIDYVQRQLHCCGI	TSPAN3	136	O60637
RCAEYTFQAEGRLCQ	ALS2CL	341	Q60I27
VFHDFRNGLCRNLVC	DDX6	376	P26196
QEDIQCRYNLACHRL	BIRC6	1921	Q9NR09
YRCRLAAALCDHDQR	ANKRD62	656	A6NC57
SYRCRLNAARCDHDQ	ANKRD36B	1041	Q8N2N9
RRCSVAGFDYCHEEN	ATP10D	451	Q9P241
REHFNLNVAEQLCCY	ABHD16B	296	Q9H3Z7
NVICAICFGRRYDHN	CYP1A1	196	P04798
HFQDFVELCCRAYNI	PIK3C2G	1091	O75747
IRFAGCYDQHNLVAC	MECOM	151	Q03112
SYRCRLNAALCDHDQ	ANKRD36C	1466	Q5JPF3
VLDEYCARNGVRGCH	CADPS	711	Q9ULU8
VAALYGCCHQRLSQR	PODXL	476	O00592
HESCGSYQRLQDFRC	DGKK	416	Q5KSL6
RYENITFNCCNHCRG	BLZF1	381	Q9H2G9
CLFHGRQDCDVERNR	HRCT1	31	Q6UXD1
LCCRRDHYVDFQELG	INHBE	246	P58166
DCAYFGVCQRQLDHN	MCF2L2	731	Q86YR7
QRLQCCHGFYESRGF	PEAR1	86	Q5VY43
CLYDNFDCHAGGRER	NOTCH3	1451	Q9UM47
VLICQFHYRRCQEAA	IL27RA	161	Q6UWB1
RRIHQCDFAGCSKVY	KLF8	271	O95600
IRNHQLYCNDCYLRF	LMO7	1661	Q8WWI1
HCFQGVYARQCDRCL	LAMB1	841	P07942
TRGLNCEQCQDFYRD	LAMB2	316	P55268
RARGNAYHLACFACF	LHX6	146	Q9UPM6
CFDCIQRYILENHDF	RFPL4B	31	Q6ZWI9
HLCNYACRRRDALTG	IKZF1	176	Q13422
FGCRCSQLDHLYRDE	NOS3	1046	P29474
QLHEYCYRDGACLLL	PTF1A	56	Q7RTS3
ALGYAIRDLCQARDC	GPRC6A	421	Q5T6X5
HCLNYERCDFEDGLC	MALRD1	66	Q5VYJ5
EVFAHRCLLACRCNF	BTBD19	41	C9JJ37
DFLLQVHDRLDRYCC	GASK1A	426	Q9UFP1
DEHYLDNLCIFCGER	CEP104	746	O60308
RCRGHCLERQNYIED	DUSP11	231	O75319
YLREQCLRDANGCKH	GFRAL	26	Q6UXV0
SCQNDELCRRHYRTF	GFRAL	226	Q6UXV0
RLFRESCVFHQGCYV	CTDSP2	186	O14595
QLVQHYSERAAGLCC	FYN	226	P06241
AENCIGIRDFALHYC	GAN	131	Q9H2C0
YDQNHLLGRACFCLL	CTR9	126	Q6PD62
NNCDYEQRERFLLFC	MARK3	686	P27448
EDPRACVACRHLYFQ	INSRR	241	P14616
GYGCRRHSELQDCFD	KLHDC1	141	Q8N7A1
EGKNCERCQLHYFRN	LAMB3	351	Q13751
RDAHRQFRDYCAICL	FHIP2A	596	Q5W0V3
FYAAELCCGLEDLQR	GRK4	291	P32298
HEVLRRCLCAGYFKN	DHX40	616	Q8IX18
RLCRAAQYACSLLGH	PEX11B	16	O96011
DHFYCDRGQLLKLSC	OR9A2	171	Q8NGT5
ERRFGILSNCNHTYC	MKRN1	296	Q9UHC7
CELCRLGYFRNASAQ	NTNG1	396	Q9Y2I2
ACDCLLQEHFYLRRR	MRPS30	146	Q9NP92
YFQFRCENGHCIPNR	SORL1	1371	Q92673
TQLGRCDRFEFECHQ	SORL1	1466	Q92673
QGRYREFCQCDFDIA	HARS2	166	P49590
FHFLDQLNYECGRCS	STAT2	61	P52630
LDCFHLYCVTRLNDR	PRKN	261	O60260
CHRCLVYLGDLSRYQ	SMG5	171	Q9UPR3
QEALFCLHDERDCLY	NKPD1	376	Q17RQ9
ADICRCLHNYNGVLE	RASGRF2	1081	O14827
VCSGLQAQILHCYRD	CHCHD6	196	Q9BRQ6
IDQCCDLGYHASLNR	SRGAP2C	276	P0DJJ0
RDCCNDCYLALEHGR	MED13	1226	Q9UHV7
EICRLRFRHFCYQEA	PGBD1	41	Q96JS3
VADICRCLHNYNAVL	RASGRF1	1116	Q13972
CQYCAQRFGRKDHLT	PLAGL2	221	Q9UPG8
GQNREERYCNEHLLC	SEMA5A	636	Q13591
FYGRNCEHDVRKENC	TDGF1	101	P13385
RDIACGCQYLEENHF	ALK	1231	Q9UM73
LNGENAYHCGLCLQR	USP17L3	246	A6NCW0
LFLECARFVHRCNRG	UNC80	1221	Q8N2C7
FDCRCGNLFCGLHRY	ZFAND5	166	O76080
LNGENAYHCGLCLQR	USP17L4	246	A6NCW7
FSGICQYLLARDCQD	VWF	406	P04275
RDCNGHLLNCYGRNE	TIAM2	131	Q8IVF5
ERSRCVYCQERFNHE	SPRED1	331	Q7Z699
IDQCCDLGYHASLNR	SRGAP2	276	O75044
FHCGCVIAEIRDYRQ	SUPT20H	136	Q8NEM7
LVYHCRRDTQLAFGC	TMEM104	441	Q8NE00
CFDHAQRQLGERCLY	UBE2O	341	Q9C0C9
LNGENAYHCGLCLQR	USP17L1	246	Q7RTZ2
IYDNQGIELHCIRRC	WDR46	261	O15213
QRLYEFIVRHFLACC	TOP3A	431	Q13472
CFDLESYLQLNCERG	ZMIZ2	621	Q8NF64
HARRQLYAACAVCFV	SLC30A3	71	Q99726
NLCGKGFYQRCHLRE	ZBTB1	581	Q9Y2K1
HRCLACARYFIDSTN	ZNF593	61	O00488
YGEDAQCVTCRLHRF	TNFRSF19	66	Q9NS68
ELCRQLFRQFCYQDS	ZNF165	46	P49910
LNFDHSDLIYRCRFC	ZNF462	916	Q96JM2
REFHCALCDYRTFSN	ZNF142	571	P52746
FYGRNCEHDVRKENC	TDGF1P3	101	P51864
YRAACFCHRNLIEIG	GTF2H3	251	Q13889
AEHCINIYQRRCEAF	TKTL1	166	P51854
LNGENAYHCGLCLQR	USP17L2	246	Q6R6M4
DCGKCFRQLAYLVEH	ZNF789	261	Q5FWF6
GCDNRDLFYCAHVVA	ZSWIM4	156	Q9H7M6