Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	neuromuscular junction	STXBP5L PCLO CD2AP EPHA7	1.61e-04	112	51	4	GO:0031594
Domain	ZnF_C3H1	ZC3H14 ZC3H18	7.04e-03	48	49	2	SM00356
Domain	WD40_repeat_dom	STXBP5L UBR4 EML1 SON	7.57e-03	297	49	4	IPR017986
Domain	BTB_2	KCNB1 KCTD17	8.53e-03	53	49	2	PF02214
Domain	T1-type_BTB	KCNB1 KCTD17	8.53e-03	53	49	2	IPR003131
Domain	Znf_CCCH	ZC3H14 ZC3H18	1.02e-02	58	49	2	IPR000571
Domain	ZF_C3H1	ZC3H14 ZC3H18	1.02e-02	58	49	2	PS50103
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	ZC3H14 NCOA6 ZNF609 MAP7D3 PNN CD2AP MDC1 HMGXB4 SAFB2 SLX4IP CHD4 ZC3H18 TOR1AIP1 SON	8.34e-11	954	52	14	36373674
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ZC3H14 NCOA6 ZNF609 MAP7D3 PNN MDC1 HMGXB4 SAFB2 CHD4 ZC3H18 NKTR TOR1AIP1 DMAP1 SON	4.28e-09	1294	52	14	30804502
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	NCOA6 ZNF609 MDC1 UBR4 AKAP13 MDM4 ZMYM5 SON FOXI1	1.43e-08	430	52	9	35044719
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MYCN NCOA6 ABLIM1 BRAF PNN MDC1 SAFB2 CHD4 ZC3H18 SON	1.91e-07	774	52	10	15302935
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	PNN MDC1 UBR4 HMGXB4 AKAP13 ZC3H18 SON	1.10e-06	361	52	7	26167880
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	JPH1 ABLIM1 KCNB1 PCLO SAFB2 FGA	1.27e-06	231	52	6	16452087
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	ZC3H14 NCOA6 ABLIM1 MAP7D3 PNN CD2AP MDC1 DMAP1	1.50e-06	549	52	8	38280479
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	ZC3H14 UBR4 SAFB2 CHD4 SON	1.52e-06	130	52	5	35545047
Pubmed	HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.	PNN MDC1 CHD4 ZC3H18 SON	2.88e-06	148	52	5	32538781
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	NCOA6 ZNF609 PNN MDC1 CHD4 DMAP1	2.99e-06	268	52	6	33640491
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	ZC3H14 PNN MDC1 SAFB2 CHD4 ZC3H18 TOR1AIP1 DMAP1 SON	4.16e-06	847	52	9	35850772
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	MYCN TCF12 MAP7D3 UBR4 HMGXB4 CHD4 MDM4 DMAP1 FOXI1	4.57e-06	857	52	9	25609649
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	PNN MDC1 SAFB2 FGA SLX4IP CHD4 TMEM43 SON	5.32e-06	652	52	8	31180492
Pubmed	Genomic differences between retinoma and retinoblastoma.	MYCN MDM4	6.57e-06	3	52	2	18785023
Pubmed	Human transcription factor protein interaction networks.	NCOA6 ZNF609 TCF12 PNN MDC1 UBR4 HMGXB4 SLX4IP ZC3H18 DMAP1 FOXI1	6.94e-06	1429	52	11	35140242
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ZC3H14 ABLIM1 ANK2 MAP7D3 PNN SAFB2 CHD4 TOR1AIP1 SON	9.13e-06	934	52	9	33916271
Pubmed	Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer.	ZC3H14 PNN SAFB2 ZC3H18 NKTR	9.25e-06	188	52	5	29721183
Pubmed	ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.	PNN SAFB2 CHD4 ZC3H18 NKTR SON	9.83e-06	330	52	6	33301849
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	CACNG3 ABLIM1 ANK2 KCNB1 STXBP5L PCLO	1.31e-05	347	52	6	17114649
Pubmed	The chromatin remodeler Mi-2beta is required for CD4 expression and T cell development.	TCF12 CHD4	1.31e-05	4	52	2	15189737
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	ZC3H14 PNN MDC1 EML1 SON EPHA7	1.56e-05	358	52	6	32460013
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	ZC3H14 MAP7D3 PNN ASPM SAFB2 OGDHL CHD4 SON	1.60e-05	759	52	8	35915203
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	MAP7D3 PNN AKAP13 ZC3H18 TOR1AIP1 SON	1.63e-05	361	52	6	30344098
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	ZC3H14 PNN MDC1 UBR4 SAFB2 CHD4 ZC3H18 DMAP1 SON	1.75e-05	1014	52	9	32416067
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	NCOA6 PNN FAM186A MDC1 ASPM	2.65e-05	234	52	5	36243803
Pubmed	Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins.	MYCN TCF12	3.28e-05	6	52	2	1922066
Pubmed	Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.	PNN ZC3H18 DMAP1	3.47e-05	42	52	3	35705031
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	JPH1 ZNF609 TCF12 HMGXB4 ASPM CHD4 ZC3H18 DMAP1 SON	3.71e-05	1116	52	9	31753913
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	ABLIM1 BRAF PNN AKAP13 SON	4.00e-05	255	52	5	15324660
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ANK2 PNN FAM186A PCLO UBR4 ASPM SAFB2 OGDHL CHD4 TMEM43	4.69e-05	1442	52	10	35575683
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ZC3H14 PNN MDC1 UBR4 CHD4 ZC3H18 SON	5.12e-05	653	52	7	22586326
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	ABLIM1 ZNF609 TCF12 CD2AP SLX4IP ZMYM5	5.19e-05	444	52	6	34795231
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	JPH1 ZC3H14 ABLIM1 PNN CD2AP AKAP13 NKTR TOR1AIP1	6.06e-05	916	52	8	32203420
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	MYCN ABLIM1 CD2AP UBR4 TTC14 AKAP13 NKTR	7.17e-05	689	52	7	36543142
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	MDC1 HMGXB4 CHD4 DMAP1	7.66e-05	150	52	4	28242625
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	JPH1 ABLIM1 MAP7D3 PNN MDC1 SAFB2 CHD4 SON	7.75e-05	949	52	8	36574265
Pubmed	Switching of α-Catenin From Epithelial to Neuronal Type During Lens Epithelial Cell Differentiation.	ANK2 ARVCF	7.84e-05	9	52	2	28692740
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ABLIM1 ANK2 KCNB1 ARVCF UBR4 SAFB2 CHD4 EML1	8.58e-05	963	52	8	28671696
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	ZC3H14 PNN SAFB2 SLBP ZC3H18 NKTR SON	8.87e-05	713	52	7	29802200
Pubmed	Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.	MDC1 CHD4 CDC14B DMAP1	9.14e-05	157	52	4	30686591
Pubmed	High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.	FREM2 MAP7D3 PNN SLBP ZC3H18	9.60e-05	307	52	5	37499664
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	JPH1 ABLIM1 TCF12 ANK2 CHD4 SON	9.64e-05	497	52	6	23414517
Pubmed	Identification of a Nuclear Exosome Decay Pathway for Processed Transcripts.	ZC3H14 ZC3H18	9.79e-05	10	52	2	27871484
Pubmed	Human RNPS1 and its associated factors: a versatile alternative pre-mRNA splicing regulator in vivo.	PNN NKTR	1.20e-04	11	52	2	14729963
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	ZC3H14 MDC1 SAFB2 CHD4 EML1 DMAP1 UQCRFS1P1	1.25e-04	754	52	7	35906200
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	ZC3H14 ABLIM1 PNN MDC1 SAFB2 CHD4 TOR1AIP1 SON	1.31e-04	1024	52	8	24711643
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	ZC3H14 PNN TMEM43 TOR1AIP1 SON	1.38e-04	332	52	5	25693804
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	MDC1 UBR4 HMGXB4 SAFB2 CHD4	1.38e-04	332	52	5	32786267
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	PNN MDC1 HMGXB4 CHD4 ZC3H18 DMAP1	1.41e-04	533	52	6	30554943
Pubmed	CHD4-regulated plasmin activation impacts lymphovenous hemostasis and hepatic vascular integrity.	FGA CHD4	1.43e-04	12	52	2	27140400
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	NCOA6 MDC1 UBR4 SAFB2 ZC3H18	1.57e-04	341	52	5	32971831
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PNN ARVCF MDC1 UBR4 ASPM SAFB2 AKAP13 CHD4 SON	1.62e-04	1353	52	9	29467282
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	PNN HMGXB4 SAFB2 CHD4 ZC3H18 TMEM43 DMAP1 SON	1.91e-04	1082	52	8	38697112
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	MYCN ABLIM1 ZNF609 TCF12 HMGXB4 DCUN1D4 ZMYM5	1.92e-04	808	52	7	20412781
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	ASPM SAFB2 OGDHL CDC14B EPHA7	2.09e-04	363	52	5	14691545
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	PNN CHD4 TOR1AIP1 DMAP1	2.10e-04	195	52	4	19454010
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	CACNG3 ABLIM1 ANK2 KCNB1 STXBP5L PCLO UBR4 TMEM43	2.70e-04	1139	52	8	36417873
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NCOA6 ABLIM1 MAP7D3 BRAF CD2AP AKAP13 MDM4	2.82e-04	861	52	7	36931259
Pubmed	Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.	PNN SAFB2 CHD4 SON	3.05e-04	215	52	4	30462309
Pubmed	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.	ZC3H14 CD2AP HMGXB4 DCUN1D4	3.05e-04	215	52	4	35973513
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ABLIM1 ZNF609 STXBP5L CD2AP TTC14 SLX4IP AKAP13 MDM4 CDC14B	3.29e-04	1489	52	9	28611215
Pubmed	Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.	ANK2 KCNB1	3.30e-04	18	52	2	37321992
Pubmed	LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis.	TCF12 CHD4	3.30e-04	18	52	2	19497860
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	TCF12 MAP7D3 CHD4 DMAP1 SON	3.70e-04	411	52	5	35182466
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZNF609 CD2AP UBR4 CHD4 ZMYM5	4.00e-04	418	52	5	34709266
Pubmed	Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner.	ABLIM1 ANK2 PCLO OGDHL	4.13e-04	233	52	4	29518331
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	ZNF609 PNN UBR4 CHD4 ZC3H18 UQCRFS1P1	4.61e-04	665	52	6	30457570
Pubmed	Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.	ANK2 PNN CHD4	4.74e-04	101	52	3	26949739
Pubmed	Proximity interactions among centrosome components identify regulators of centriole duplication.	ABLIM1 MAP7D3 NKTR	4.74e-04	101	52	3	24613305
Pubmed	Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.	ZNF609 PNN SAFB2 ZC3H18	4.91e-04	244	52	4	29884807
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	ZC3H14 NCOA6 ABLIM1 ZNF609 BRAF PNN ARVCF CHD4	4.94e-04	1247	52	8	27684187
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	PNN CHD4 ZC3H18	5.02e-04	103	52	3	32744500
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	ABLIM1 ARVCF SAFB2 DMAP1	5.07e-04	246	52	4	15345747
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	ZC3H14 ABLIM1 MAP7D3 PNN MDC1 SAFB2 ZC3H18 TMEM43	5.21e-04	1257	52	8	36526897
Pubmed	Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.	MDC1 SLX4IP CHD4	5.46e-04	106	52	3	19394292
Pubmed	SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.	PNN CHD4 NKTR SON	6.14e-04	259	52	4	30404004
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	JPH1 ABLIM1 ANK2 MAP7D3 CD2AP ZC3H18	6.40e-04	708	52	6	39231216
Pubmed	Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation.	TCF12 ANK2	6.43e-04	25	52	2	32266943
Pubmed	Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit.	MYCN KCTD17	6.43e-04	25	52	2	28923932
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	ZC3H14 MDC1 TTC14 SAFB2 CHD4 DMAP1 SON	6.46e-04	989	52	7	36424410
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	ABLIM1 MAP7D3 PNN TOR1AIP1	6.51e-04	263	52	4	34702444
Pubmed	Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.	ZC3H14 PNN SON	6.74e-04	114	52	3	31553912
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	NCOA6 ABLIM1 ZNF609 HMGXB4 ASPM	6.93e-04	472	52	5	38943005
Pubmed	Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation.	MDC1 CHD4 TOR1AIP1 KCTD17	7.08e-04	269	52	4	30442662
Pubmed	Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.	CHD4 ZC3H18 DMAP1	7.09e-04	116	52	3	21549307
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	ZC3H14 ZNF609 MAP7D3 CD2AP AKAP13 SON	7.19e-04	724	52	6	36232890
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	ZC3H14 PNN CHD4 NKTR SON	7.27e-04	477	52	5	31300519
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	ZNF609 UBR4 ASPM SLBP ZC3H18 NKTR KCTD17 DMAP1	7.43e-04	1327	52	8	32694731
Pubmed	Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.	NCOA6 CD2AP HMGXB4	7.64e-04	119	52	3	23508102
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	JPH1 ABLIM1 ZNF609 MDC1 AKAP13 TOR1AIP1	7.67e-04	733	52	6	34672954
Pubmed	A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells.	CD2AP MDC1 TOR1AIP1	8.02e-04	121	52	3	22412018
Pubmed	The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation.	BRAF STXBP5L	8.08e-04	28	52	2	24448406
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	NCOA6 MDC1 SAFB2 ZC3H18	8.55e-04	283	52	4	30585729
Pubmed	Murine chromosomal location of eight members of the hepatocyte nuclear factor 3/fork head winged helix family of transcription factors.	MYCN FOXI1	8.67e-04	29	52	2	7789972
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	ABLIM1 ZNF609 TCF12 ZC3H18 TMEM43 TOR1AIP1	8.87e-04	754	52	6	33060197
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	ABLIM1 PNN CD2AP UBR4 CHD4 ZC3H18 TOR1AIP1 SON	9.01e-04	1367	52	8	32687490
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	BRAF PNN AKAP13 DMAP1 SON	9.21e-04	503	52	5	16964243
Pubmed	The functional interactome landscape of the human histone deacetylase family.	ZNF609 PNN CHD4 SON	9.24e-04	289	52	4	23752268
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	MDC1 ASPM CHD4 DMAP1 SON	9.46e-04	506	52	5	30890647
Pubmed	Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.	MYCN FREM2 FOXI1	9.86e-04	130	52	3	28705898
Interaction	SMC5 interactions	ZC3H14 NCOA6 ZNF609 MAP7D3 PNN CD2AP MDC1 HMGXB4 SAFB2 SLX4IP CHD4 ZC3H18 TOR1AIP1 SON	1.51e-07	1000	52	14	int:SMC5
Interaction	SNIP1 interactions	MYCN ZC3H14 PNN TTC14 CHD4 ZC3H18 NKTR ZMYM5 SON	1.07e-06	417	52	9	int:SNIP1
Interaction	NKAP interactions	MYCN ZC3H14 PNN TTC14 ZC3H18 NKTR	1.12e-06	132	52	6	int:NKAP
Interaction	ZC3H11A interactions	MYCN ZC3H14 PNN SAFB2 ZC3H18 NKTR UQCRFS1P1	1.27e-06	215	52	7	int:ZC3H11A
Interaction	CSNK2A1 interactions	MYCN PNN CD2AP MDC1 OGDHL SLBP CHD4 ZC3H18 NKTR CDC14B TOR1AIP1 DMAP1	4.31e-06	956	52	12	int:CSNK2A1
Interaction	SNRNP40 interactions	MYCN ZNF609 TCF12 PNN MDC1 TTC14 SLBP ZC3H18 NKTR SON	4.43e-06	637	52	10	int:SNRNP40
Interaction	MKI67 interactions	MYCN ZC3H14 NCOA6 PNN MDC1 ASPM AKAP13 CHD4 DMAP1 SON	5.15e-06	648	52	10	int:MKI67
Interaction	MEN1 interactions	ZC3H14 NCOA6 ZNF609 PNN MDC1 UBR4 SAFB2 CHD4 ZC3H18 TOR1AIP1 DMAP1 SON	9.13e-06	1029	52	12	int:MEN1
Interaction	DHX8 interactions	ZC3H14 PNN TTC14 CHD4 ZC3H18 NKTR SON	9.55e-06	292	52	7	int:DHX8
Interaction	TERF2IP interactions	ZC3H14 NCOA6 ZNF609 MDC1 HMGXB4 SLX4IP ZC3H18 TOR1AIP1 DMAP1	1.05e-05	552	52	9	int:TERF2IP
Interaction	SRSF4 interactions	MYCN ZC3H14 PNN UBR4 ZC3H18 NKTR SON	1.14e-05	300	52	7	int:SRSF4
Interaction	SAP18 interactions	MYCN ZC3H14 PNN CHD4 ZC3H18 NKTR SON	1.27e-05	305	52	7	int:SAP18
Interaction	ZNF543 interactions	JPH1 ZC3H18 NKTR	2.09e-05	21	52	3	int:ZNF543
Interaction	CCDC85A interactions	JPH1 MAP7D3 ARVCF MDC1	2.37e-05	65	52	4	int:CCDC85A
Interaction	MYCN interactions	MYCN ZC3H14 ZNF609 TCF12 PNN HMGXB4 SAFB2 SLBP AKAP13 CHD4 ZC3H18 UQCRFS1P1 SON	3.34e-05	1373	52	13	int:MYCN
Interaction	DOT1L interactions	MYCN ZC3H14 PNN MDC1 SAFB2 CHD4 ZC3H18 TOR1AIP1 DMAP1 SON	3.44e-05	807	52	10	int:DOT1L
Interaction	BRD3 interactions	JPH1 PNN MDC1 HMGXB4 CHD4 CDC14B DMAP1 SON	3.59e-05	494	52	8	int:BRD3
Interaction	SRSF6 interactions	MYCN ZC3H14 PNN SLBP CHD4 ZC3H18 NKTR SON	4.08e-05	503	52	8	int:SRSF6
Interaction	SNRPB interactions	MYCN ZC3H14 PNN MDC1 SAFB2 ZC3H18 NKTR SON	4.96e-05	517	52	8	int:SNRPB
Interaction	CPSF6 interactions	MYCN ZC3H14 PNN MDC1 SAFB2 ZC3H18 NKTR SON	5.59e-05	526	52	8	int:CPSF6
Interaction	RBM39 interactions	MYCN ZC3H14 NCOA6 PNN MDC1 TTC14 SAFB2 CHD4 ZC3H18 NKTR SON	5.73e-05	1042	52	11	int:RBM39
Interaction	NKAPD1 interactions	MYCN ZC3H14 PNN HMGXB4 NKTR	5.87e-05	161	52	5	int:NKAPD1
Interaction	CCDC9 interactions	MYCN ZC3H14 PNN MDC1	7.83e-05	88	52	4	int:CCDC9
Interaction	IFI16 interactions	ZC3H14 PNN MDC1 ASPM SAFB2 CHD4 TMEM43 TOR1AIP1 SON	7.85e-05	714	52	9	int:IFI16
Interaction	SRPK2 interactions	MYCN PNN MDC1 UBR4 HMGXB4 AKAP13 ZC3H18 NKTR SON	8.11e-05	717	52	9	int:SRPK2
Interaction	NKTR interactions	PNN ZC3H18 NKTR SON	8.55e-05	90	52	4	int:NKTR
Interaction	CRNKL1 interactions	MYCN ANK2 PNN CHD4 ZC3H18	9.19e-05	177	52	5	int:CRNKL1
Interaction	HMGA1 interactions	MYCN PCLO MDC1 SAFB2 CHD4 ZC3H18 CDC14B	9.53e-05	419	52	7	int:HMGA1
Interaction	HNRNPUL2 interactions	MYCN ZC3H14 MDC1 SAFB2 CHD4 ZC3H18	1.00e-04	291	52	6	int:HNRNPUL2
Interaction	PPP1CC interactions	MAP7D3 PNN SAFB2 AKAP13 CHD4 ZC3H18 MDM4 TOR1AIP1 SON	1.01e-04	738	52	9	int:PPP1CC
Interaction	SRSF7 interactions	MYCN ZC3H14 PNN CHD4 ZC3H18 NKTR SON	1.04e-04	425	52	7	int:SRSF7
Interaction	SFSWAP interactions	MYCN PNN CHD4 ZC3H18	1.10e-04	96	52	4	int:SFSWAP
Interaction	ELAVL2 interactions	MYCN ZC3H14 PNN SAFB2 ZC3H18	1.22e-04	188	52	5	int:ELAVL2
Interaction	PNN interactions	MYCN ZC3H14 PNN CHD4 ZC3H18 NKTR	1.23e-04	302	52	6	int:PNN
Interaction	C2orf49 interactions	MYCN PNN MDC1	1.28e-04	38	52	3	int:C2orf49
Interaction	SNRPC interactions	MYCN ZC3H14 PNN SAFB2 ZC3H18 NKTR SON	1.29e-04	440	52	7	int:SNRPC
Interaction	THRAP3 interactions	MYCN ZC3H14 PNN PCLO MDC1 CHD4 ZC3H18	1.35e-04	443	52	7	int:THRAP3
Interaction	CSHL1 interactions	MYCN UBR4	1.36e-04	7	52	2	int:CSHL1
Interaction	CLK2 interactions	ZC3H14 PNN ZC3H18 NKTR SON	1.45e-04	195	52	5	int:CLK2
Interaction	ZBTB2 interactions	PNN MDC1 SAFB2 CHD4 ZC3H18 NKTR SON	1.48e-04	450	52	7	int:ZBTB2
Interaction	PRPF19 interactions	MYCN PNN UBR4 CHD4 ZC3H18 NKTR SON	1.48e-04	450	52	7	int:PRPF19
Interaction	BACC1 interactions	MYCN CD2AP HMGXB4 CHD4	1.50e-04	104	52	4	int:BACC1
Interaction	SRSF11 interactions	MYCN ZC3H14 PNN ZC3H18 SON	1.75e-04	203	52	5	int:SRSF11
Interaction	SNRNP70 interactions	MYCN ZC3H14 PNN SAFB2 SLBP CHD4 ZC3H18 NKTR CDC14B SON	1.79e-04	984	52	10	int:SNRNP70
Interaction	DELE1 interactions	MYCN BRAF	1.81e-04	8	52	2	int:DELE1
Interaction	PSIP1 interactions	MYCN CD2AP CHD4 ZC3H18 SON	1.83e-04	205	52	5	int:PSIP1
Interaction	NUP43 interactions	NCOA6 ZNF609 PNN MDC1 TTC14 ZC3H18 NKTR SON	1.85e-04	625	52	8	int:NUP43
Interaction	NUMA1 interactions	MYCN NCOA6 PNN MDC1 ASPM CHD4 ZC3H18	1.91e-04	469	52	7	int:NUMA1
Interaction	ZNF207 interactions	MYCN ZC3H14 MDC1 ZC3H18	1.92e-04	111	52	4	int:ZNF207
Interaction	SF3A1 interactions	MYCN ZC3H14 PNN MDC1 CHD4 ZC3H18 SON	1.96e-04	471	52	7	int:SF3A1
Interaction	DDX23 interactions	MYCN PNN TTC14 SAFB2 CHD4 ZC3H18 NKTR	2.20e-04	480	52	7	int:DDX23
Interaction	SNRPA interactions	MYCN ZC3H14 PNN SAFB2 ZC3H18 NKTR SON	2.26e-04	482	52	7	int:SNRPA
Interaction	SUZ12 interactions	MYCN ZC3H14 ABLIM1 HMGXB4 SAFB2 CHD4 ZC3H18 SON	2.26e-04	644	52	8	int:SUZ12
Interaction	BUD31 interactions	MYCN ZC3H18 DCUN1D4 SON	2.28e-04	116	52	4	int:BUD31
Interaction	IK interactions	MYCN TTC14 SAFB2 CHD4 ZC3H18	2.28e-04	215	52	5	int:IK
Interaction	RBBP6 interactions	MYCN PNN CHD4 ZC3H18 SON	2.33e-04	216	52	5	int:RBBP6
Interaction	HMGB1 interactions	MYCN ZC3H14 PNN SAFB2 ZC3H18 NKTR CDC14B	2.38e-04	486	52	7	int:HMGB1
Interaction	RBM17 interactions	MYCN MDC1 CHD4 ZC3H18 SON	2.43e-04	218	52	5	int:RBM17
Interaction	CAMKV interactions	JPH1 ZC3H14 PNN ZC3H18	2.43e-04	118	52	4	int:CAMKV
Interaction	CALM3 interactions	MAP7D3 PNN UBR4 ASPM DMAP1 EPHA7	2.45e-04	343	52	6	int:CALM3
Interaction	SRRM1 interactions	MYCN ZC3H14 PNN AKAP13 CHD4 ZC3H18	2.65e-04	348	52	6	int:SRRM1
Interaction	SRSF9 interactions	MYCN MDC1 CHD4 ZC3H18 CDC14B	2.76e-04	224	52	5	int:SRSF9
Interaction	CUL7 interactions	MYCN ZC3H14 PNN MDC1 SAFB2 CHD4 ZC3H18 SON EPHA7	2.79e-04	845	52	9	int:CUL7
Interaction	EIF4A3 interactions	MYCN ZC3H14 PNN MDC1 CHD4 ZC3H18 SON	2.79e-04	499	52	7	int:EIF4A3
Interaction	FOXK2 interactions	MYCN UBR4 HMGXB4 CHD4 DMAP1	2.81e-04	225	52	5	int:FOXK2
Interaction	YWHAG interactions	MYCN NCOA6 ABLIM1 MAP7D3 BRAF PNN CD2AP AKAP13 NKTR MDM4 SON	2.82e-04	1248	52	11	int:YWHAG
Interaction	PAGR1 interactions	NCOA6 SLX4IP FOXI1	3.09e-04	51	52	3	int:PAGR1
Interaction	CD2BP2 interactions	PNN AKNA CHD4 ZC3H18 NKTR	3.24e-04	232	52	5	int:CD2BP2
Interaction	RNF2 interactions	MYCN ZC3H14 NCOA6 PCLO CHD4 MDM4 DMAP1 SON FOXI1	3.34e-04	866	52	9	int:RNF2
Interaction	SSRP1 interactions	MYCN ZC3H14 PNN HMGXB4 SAFB2 CHD4 ZC3H18 SON	3.43e-04	685	52	8	int:SSRP1
Interaction	ZCCHC10 interactions	JPH1 HMGXB4 ASPM NKTR SON	3.50e-04	236	52	5	int:ZCCHC10
Interaction	SFN interactions	NCOA6 ABLIM1 MAP7D3 BRAF CD2AP AKAP13 ZC3H18 MDM4	3.67e-04	692	52	8	int:SFN
Interaction	HNRNPAB interactions	MYCN PNN PCLO MDC1 CHD4 ZC3H18	3.72e-04	371	52	6	int:HNRNPAB
Interaction	PPP1CA interactions	MYCN BRAF MDC1 ASPM ZC3H18 MDM4 TOR1AIP1 SON	3.82e-04	696	52	8	int:PPP1CA
Interaction	TOP1 interactions	MYCN ZC3H14 NCOA6 PNN SAFB2 CHD4 ZC3H18 SON	3.82e-04	696	52	8	int:TOP1
Interaction	SH3BP1 interactions	ZC3H14 CD2AP FGA	3.87e-04	55	52	3	int:SH3BP1
Interaction	LUC7L interactions	MYCN ZC3H14 PNN ZC3H18 NKTR	3.93e-04	242	52	5	int:LUC7L
Interaction	TPRX2 interactions	NCOA6 ZNF609 DMAP1	4.08e-04	56	52	3	int:TPRX2
Interaction	SAFB interactions	MYCN SAFB2 CHD4 ZC3H18 SON	4.08e-04	244	52	5	int:SAFB
Interaction	YAP1 interactions	ZC3H14 NCOA6 ABLIM1 MAP7D3 PNN CD2AP MDC1 CHD4 DMAP1 FOXI1	4.22e-04	1095	52	10	int:YAP1
Interaction	YWHAH interactions	ZC3H14 NCOA6 ABLIM1 MAP7D3 BRAF PNN CD2AP AKAP13 NKTR MDM4	4.44e-04	1102	52	10	int:YWHAH
Interaction	SNRPF interactions	MYCN ZC3H14 PNN CHD4 ZC3H18 NKTR	4.53e-04	385	52	6	int:SNRPF
Interaction	MAD2L1 interactions	PNN MDC1 CHD4 TOR1AIP1 DMAP1	4.73e-04	252	52	5	int:MAD2L1
Interaction	CWC22 interactions	MYCN PNN CHD4 ZC3H18	4.79e-04	141	52	4	int:CWC22
Interaction	SUDS3 interactions	ZNF609 MDC1 HMGXB4 CHD4	4.79e-04	141	52	4	int:SUDS3
Interaction	HNRNPM interactions	MYCN ERICH3 MAP7D3 PNN CHD4 ZC3H18 TOR1AIP1 SON	4.91e-04	723	52	8	int:HNRNPM
Interaction	PABPC5 interactions	ZC3H14 PNN SAFB2 ZC3H18	4.92e-04	142	52	4	int:PABPC5
Interaction	PES1 interactions	MYCN PNN CHD4 ZC3H18 CDC14B	5.26e-04	258	52	5	int:PES1
Interaction	DYNLL2 interactions	MYCN NCOA6 ZNF609 CHD4 ZC3H18	5.74e-04	263	52	5	int:DYNLL2
Interaction	PML interactions	ABLIM1 ZNF609 TCF12 CD2AP MDC1 HMGXB4 SLX4IP CHD4 ZMYM5	5.75e-04	933	52	9	int:PML
Interaction	ISG20L2 interactions	MYCN ZC3H18 EML1	5.77e-04	63	52	3	int:ISG20L2
Interaction	TAF15 interactions	MYCN ZNF609 PNN SAFB2 CHD4 ZC3H18	6.15e-04	408	52	6	int:TAF15
Interaction	NCBP3 interactions	MYCN ZC3H14 PNN CHD4	7.01e-04	156	52	4	int:NCBP3
Interaction	EP300 interactions	MYCN NCOA6 TCF12 MDC1 SAFB2 OGDHL SLBP CHD4 MDM4 SON FOXI1	7.52e-04	1401	52	11	int:EP300
Interaction	RNPS1 interactions	MYCN ZC3H14 PNN ZC3H18 NKTR SON	7.61e-04	425	52	6	int:RNPS1
Interaction	ZNF816 interactions	ZC3H18 NKTR	7.66e-04	16	52	2	int:ZNF816
Interaction	SUMO2 interactions	MDC1 UBR4 HMGXB4 SAFB2 SLX4IP CHD4 ZMYM5	7.66e-04	591	52	7	int:SUMO2
Interaction	WBP11 interactions	MYCN UBR4 CHD4 ZC3H18	7.70e-04	160	52	4	int:WBP11
Interaction	BRD2 interactions	PNN MDC1 HMGXB4 CHD4 CDC14B DMAP1	7.99e-04	429	52	6	int:BRD2
Interaction	NAA40 interactions	ZC3H14 ABLIM1 ANK2 MAP7D3 PNN SAFB2 CHD4 TOR1AIP1 SON	8.06e-04	978	52	9	int:NAA40
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	JPH1 NCOA6 PNN SWT1 STXBP5L PCLO ASPM SAFB2 NKTR TMEM43 ZMYM5	4.29e-06	831	52	11	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000	JPH1 MYCN FREM2 MAP7D3 PNN ARVCF PCLO MDC1 ASPM SLX4IP	1.27e-04	994	52	10	Facebase_RNAseq_e8.5_Floor Plate_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	NCOA6 TCF12 ANK2 PNN ARVCF SWT1 MDC1 TTC14 ASPM CHD4 DCUN1D4 ZMYM5	1.66e-04	1459	52	12	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	NCOA6 TCF12 ANK2 PNN SWT1 MDC1 TTC14 ASPM CHD4 DCUN1D4 ZMYM5	1.91e-04	1257	52	11	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500	JPH1 MYCN FREM2 MAP7D3 ARVCF PCLO MDC1	1.94e-04	495	52	7	Facebase_RNAseq_e8.5_Floor Plate_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500	FREM2 MAP7D3 PNN ARVCF STXBP5L PCLO ASPM	2.01e-04	498	52	7	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BRAF PNN TTC14 AKNA NKTR MDM4	1.19e-07	199	52	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	PNN TTC14 AKNA NKTR MDM4	7.99e-07	147	52	5	94998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 KCNB1 PCLO AKAP13 SON	2.68e-06	188	52	5	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 PCLO UBR4 NKTR SON	3.04e-06	193	52	5	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 PCLO UBR4 NKTR SON	3.04e-06	193	52	5	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FREM2 ERICH3 ANK2 STXBP5L PCLO	3.12e-06	194	52	5	b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon\|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.	MYCN PNN PCLO HMGXB4 EML1	3.12e-06	194	52	5	4903a0d6e36599bcb83b179462e5b949df9eb685
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNB1 PCLO CHD4 NKTR SON	3.20e-06	195	52	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	(1)_T_cells-(1)_T_CD4_naive\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ABLIM1 PNN TTC14 NKTR MDM4	3.20e-06	195	52	5	d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNB1 PCLO CHD4 NKTR SON	3.20e-06	195	52	5	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	BRAF PNN AKAP13 CHD4 SON	3.62e-06	200	52	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PNN AKAP13 NKTR MDM4 SON	3.62e-06	200	52	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	IPF-Epithelial-Ionocyte\|IPF / Disease state, Lineage and Cell class	ANK2 PCLO OGDHL FOXI1	3.65e-05	160	52	4	d65d19f4fae60836bfd4303a1bb7de34e9d83e35
ToppCell	IPF-Epithelial-Ionocyte\|World / Disease state, Lineage and Cell class	ANK2 PCLO OGDHL FOXI1	3.74e-05	161	52	4	f1cd5c938cdc08ad8995371b72493850a6cf277a
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNN PCLO TTC14 SON	4.21e-05	166	52	4	66026988509e39e41274fa0de738383219e8ff30
ToppCell	3'_v3\|World / Manually curated celltypes from each tissue	PNN AKAP13 NKTR MDM4	5.53e-05	178	52	4	42502f14d9c756df8104900ac6484477b885d3d9
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERICH3 ARVCF STXBP5L PCLO	5.65e-05	179	52	4	f2e8fc975c30992611630197b79daaeef7c4211d
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	TCF12 TTC14 NKTR EML1	5.90e-05	181	52	4	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 STXBP5L PCLO EPHA7	6.29e-05	184	52	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 STXBP5L PCLO EPHA7	6.29e-05	184	52	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 STXBP5L PCLO EPHA7	6.29e-05	184	52	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ANK2 STXBP5L PCLO OGDHL	6.29e-05	184	52	4	9e5f98f9113e5e38bdadba6d9d2c346177fb35fe
ToppCell	Mild_COVID-19-Epithelial-AT1/AT2\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	FREM2 ANK2 OGDHL FOXI1	6.42e-05	185	52	4	c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	AKNA AKAP13 NKTR MDM4	6.69e-05	187	52	4	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ERICH3 ANK2 STXBP5L PCLO	6.83e-05	188	52	4	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	JPH1 ABLIM1 ANK2 AKAP13	6.98e-05	189	52	4	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	JPH1 ABLIM1 ANK2 AKAP13	7.12e-05	190	52	4	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ERICH3 ANK2 STXBP5L PCLO	7.12e-05	190	52	4	5f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	PNN ASPM NKTR SON	7.41e-05	192	52	4	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	droplet-Pancreas-Endocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBR4 TTC14 NKTR SON	7.41e-05	192	52	4	0dfd1e9896c34aee0f842f8de5d0e3af62a15f68
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ZNF609 TCF12 BRAF AKAP13	7.56e-05	193	52	4	779276e775cb2492e8dd36436295a536084a6415
ToppCell	remission\|World / disease stage, cell group and cell class	ABLIM1 TTC14 AKNA NKTR	7.56e-05	193	52	4	86cfd0c230ba96a43d343216935952fff6a5254e
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYCN ANK2 ARVCF PCLO	7.56e-05	193	52	4	a189d46c39067b717509cd144e0225cc93d7731d
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 UBR4 NKTR SON	7.72e-05	194	52	4	0b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PNN AKNA NKTR SON	8.03e-05	196	52	4	a9157809122e6fc5783a291522f103bef30943e4
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	BRAF PNN NKTR MDM4	8.19e-05	197	52	4	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	PNN ASPM SAFB2 NKTR	8.19e-05	197	52	4	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	moderate-Lymphoid-CTL\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PNN AKNA NKTR SON	8.35e-05	198	52	4	0a868098b1ee4b28b2149ed766acb09e9c0ce14c
ToppCell	PBMC_fresh-frozen\|World / Compartment, severity and other cell annotations on 10x 3' data (130k)	PNN AKAP13 NKTR SON	8.35e-05	198	52	4	dcc223a0396b8b673e4ed8c6733ec6cd74e9a03a
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	BRAF PNN NKTR MDM4	8.35e-05	198	52	4	44417089b62056269cac38d3134ff209c05b7007
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BRAF PNN NKTR MDM4	8.35e-05	198	52	4	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	ABLIM1 ANK2 PCLO EPHA7	8.51e-05	199	52	4	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	ABLIM1 ANK2 PCLO EPHA7	8.51e-05	199	52	4	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell	mLN-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	PNN CD86 AKAP13 SON	8.68e-05	200	52	4	e3c15e0e1c2602b0cc9ab8cc50c978d265350c94
ToppCell	COVID-19-COVID-19_Mild\|COVID-19 / Disease, condition lineage and cell class	PNN AKNA NKTR MDM4	8.68e-05	200	52	4	62c25042086f1afd1102e0720e933c2e476468fd
Drug	Etifenin [63245-28-3]; Down 200; 12.4uM; PC3; HT_HG-U133A	ABLIM1 PCLO HMGXB4 AKAP13 NKTR CDC14B SON	1.58e-07	178	52	7	3998_DN
Drug	Neostigmine bromide [114-80-7]; Down 200; 13.2uM; PC3; HT_HG-U133A	ABLIM1 ZNF609 PCLO HMGXB4 NKTR CDC14B SON	2.29e-07	188	52	7	6735_DN
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	ZC3H14 MAP7D3 PNN HMGXB4 CHD4 NKTR DCUN1D4	2.93e-07	195	52	7	1080_DN
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	ZNF609 MAP7D3 CHD4 NKTR DCUN1D4 SON	4.48e-06	189	52	6	1045_DN
Drug	Isoammodendrine	PNN AKAP13	5.12e-06	2	52	2	CID000108191
Drug	ICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A_EA	HMGXB4 AKAP13 CHD4 NKTR SON	5.19e-05	177	52	5	985_DN
Drug	Captopril [62571-86-2]; Down 200; 17.2uM; PC3; HT_HG-U133A	HMGXB4 CHD4 NKTR CDC14B SON	5.47e-05	179	52	5	4585_DN
Drug	AG-012559 [369370-06-9]; Up 200; 10uM; PC3; HT_HG-U133A	ABLIM1 ZNF609 PNN AKAP13 EML1	7.82e-05	193	52	5	6920_UP
Drug	Serotonin hydrochloride [153-98-0]; Up 200; 18.8uM; MCF7; HT_HG-U133A	ZNF609 KCNB1 AKAP13 MDM4 CDC14B	7.82e-05	193	52	5	5268_UP
Drug	Tadjakonine [11087-94-8]; Up 200; 7.4uM; PC3; HT_HG-U133A	OGDHL NKTR EML1 DCUN1D4 TOR1AIP1	8.01e-05	194	52	5	4599_UP
Drug	Medrysone [2668-66-8]; Down 200; 11.6uM; PC3; HT_HG-U133A	ZNF609 SAFB2 OGDHL TOR1AIP1 KCTD17	8.21e-05	195	52	5	3705_DN
Drug	Aminopurine, 6-benzyl [1214-39-7]; Down 200; 17.8uM; MCF7; HT_HG-U133A	ZNF609 PCLO SAFB2 MDM4 CDC14B	8.21e-05	195	52	5	4748_DN
Drug	Diethylstilbestrol [56-53-1]; Down 200; 15uM; PC3; HT_HG-U133A	ZNF609 MAP7D3 STXBP5L MDM4 KCTD17	8.21e-05	195	52	5	3812_DN
Drug	Finasteride [98319-26-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A	ARVCF PCLO NKTR MDM4 KCTD17	8.41e-05	196	52	5	4766_DN
Drug	Ajmalicine hydrochloride [4373-34-6]; Down 200; 10.2uM; MCF7; HT_HG-U133A	ABLIM1 ZNF609 MAP7D3 CHD4 MDM4	8.82e-05	198	52	5	2898_DN
Drug	Hexamethonium dibromide dihydrate [55-97-0]; Down 200; 10uM; MCF7; HT_HG-U133A	ARVCF AKAP13 EML1 CDC14B ZMYM5	8.82e-05	198	52	5	1482_DN
Drug	Clofilium tosylate [92953-10-1]; Up 200; 7.8uM; PC3; HT_HG-U133A	ZNF609 ARVCF STXBP5L SAFB2 EPHA7	8.82e-05	198	52	5	4492_UP
Drug	Diflunisal [22494-42-4]; Up 200; 16uM; PC3; HT_HG-U133A	KCNB1 ARVCF CDC14B ZMYM5 KCTD17	9.03e-05	199	52	5	4210_UP
Drug	Apomorphine hydrochloride hemihydrate [41372-20-7]; Down 200; 6.4uM; MCF7; HT_HG-U133A	ZNF609 AKAP13 DCUN1D4 ZMYM5 SON	9.03e-05	199	52	5	5283_DN
Drug	Benoxinate hydrochloride [5987-82-6]; Down 200; 11.6uM; MCF7; HT_HG-U133A	MAP7D3 ARVCF SAFB2 EML1 CDC14B	9.25e-05	200	52	5	1476_DN
Disease	intellectual disability (implicated_via_orthology)	ZC3H14 ANK2 UBR4	2.67e-04	75	49	3	DOID:1059 (implicated_via_orthology)
Disease	Adenoid Cystic Carcinoma	MYCN ASPM SON	6.21e-04	100	49	3	C0010606
Disease	acute lymphoblastic leukemia (is_marker_for)	CD86 FGA	1.46e-03	34	49	2	DOID:9952 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
ETVPKVTSRSRSKTS	ERICH3	176	Q5RHP9
STRIKTEEEAFSSKR	DCUN1D4	91	Q92564
RKSSSSSEDRNRMKT	BRAF	426	P15056
TSEDGTTRRTETKVT	ARVCF	111	O00192
SEKSKVTSSERTSAR	ABLIM1	16	O14639
ITKRTTRSASRKSSV	CDC14B	471	O60729
TRSASRKSSVKSLSI	CDC14B	476	O60729
STEKTAETETSRSRE	AKAP13	561	Q12802
RTKSTSDNETSRKNE	CACNG3	41	O60359
KEGSVKLRTRTSSSE	CD2AP	221	Q9Y5K6
RSDEAQRVFKSSKTS	CD86	306	P42081
STTASVARKRKSDGS	ASPM	566	Q8IZT6
VLVTSESRKVSSSSE	ANK2	2651	Q01484
SERRMVKKSRTTSSS	MDC1	176	Q14676
LKQSAEESSTSRKRT	MDM4	136	O15151
DLSKSSSVTVRSRKT	FREM2	2036	Q5SZK8
SESKSSISSKRSSVR	JPH1	226	Q9HDC5
SKSRTTDTFRSEQKL	PCLO	111	Q9Y6V0
RRRTKKSVDTSVQTD	PCLO	3461	Q9Y6V0
KNSRSDRKRSISESS	PNN	681	Q9H307
ESRSAVSSRTKTSKL	OGDHL	96	Q9ULD0
QKDIKVSSRGRTSST	TCF12	546	Q99081
EATTVKRKASSSEGS	HMGXB4	471	Q9UGU5
RERTYSTVKTKSTSA	EPHA7	486	Q15375
GLSSESSRKTKSTEE	KCTD17	201	Q8N5Z5
SSTKDITSAVQSKRR	NCOA6	2046	Q14686
TKRTLSETSSSKSFE	KCNB1	491	Q14721
RRESASSSSSVKKAK	DMAP1	451	Q9NPF5
SGAEKATTRRKASST	AKNA	1291	Q7Z591
KEKVTSGSTTTTRRS	FGA	446	P02671
TTRRSCSKTVTKTVI	FGA	456	P02671
KTRKADETNTTSRSS	MAP7D3	841	Q8IWC1
TKSNIKRTSSSERVS	EML1	126	O00423
RKRKSDVSSSTASLA	FOXI1	216	Q12951
KSLSRVAKETSESTR	FAM186A	641	A6NE01
VSDGSTSRSSRSRKK	CHD4	331	Q14839
SSTSTRREHVKVKTS	TMEM43	6	Q9BTV4
RERKSSSGSSDSKES	SLBP	106	Q14493
ESSKSSTRRMKSSCD	NKTR	466	P30414
SRSPSRSRSKSETKS	NKTR	1311	P30414
SSSSIRSVSSEKRKL	SWT1	41	Q5T5J6
SRSSSISSIDKDSKE	STXBP5L	816	Q9Y2K9
KSSVTSKSQTRRDTV	SLX4IP	176	Q5VYV7
SKSQTRRDTVETSSD	SLX4IP	181	Q5VYV7
TKEQSDVTTSERTRS	C12orf60	161	Q5U649
SVTTVKARSRDSDES	TOR1AIP1	231	Q5JTV8
TVEKRRSSSNTKAVT	MYCN	281	P04198
PSRVSTDTRTSKASK	SRRM5	91	B3KS81
TDTRTSKASKASDVR	SRRM5	96	B3KS81
NSSSEDSKGSKRVRT	ZNF609	451	O15014
KRRKSTSSSSVSSAD	TTC14	471	Q96N46
KTTSRSKERSSKSQD	SAFB2	586	Q14151
STSSLSRSKTKTGVR	ZMYM5	156	Q9UJ78
LDSTKSSRESTEARK	UQCRFS1P1	106	P0C7P4
KRKTATITTRTSSQV	UBR4	2271	Q5T4S7
KRDSRVSTSSQESKT	ZC3H14	126	Q6PJT7
SSEHKSRKRTSESRS	SON	1831	P18583
STKSGKASTLSRREE	ZC3H18	916	Q86VM9