Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprocollagen glucosyltransferase activity

PLOD3 PLOD2

5.23e-053842GO:0033823
GeneOntologyMolecularFunctionprocollagen-lysine 5-dioxygenase activity

PLOD3 PLOD2

5.23e-053842GO:0008475
GeneOntologyMolecularFunctionGABA-gated chloride ion channel activity

GABRQ GABRA3 GABRA5

5.60e-0518843GO:0022851
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH3 DNAH7 DYNC1H1

5.60e-0518843GO:0008569
GeneOntologyMolecularFunctionGABA-A receptor activity

GABRQ GABRA3 GABRA5

6.63e-0519843GO:0004890
GeneOntologyMolecularFunctionpeptidyl-lysine 5-dioxygenase activity

PLOD3 PLOD2

1.04e-044842GO:0070815
GeneOntologyMolecularFunctionGABA receptor activity

GABRQ GABRA3 GABRA5

1.04e-0422843GO:0016917
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH3 MYO1F MYO1B DNAH7 DYNC1H1

1.41e-04118845GO:0003774
GeneOntologyMolecularFunction2'-5'-oligoadenylate synthetase activity

OASL OAS3

1.73e-045842GO:0001730
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH3 DNAH7 DYNC1H1

2.18e-0428843GO:0051959
GeneOntologyMolecularFunctionserine-type peptidase activity

DPP4 DPP9 CORIN MMP9 PRSS58 F7

2.40e-04207846GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

DPP4 DPP9 CORIN MMP9 PRSS58 F7

2.72e-04212846GO:0017171
GeneOntologyMolecularFunctionsteroid hormone binding

ATP1A1 ATP1A3

3.62e-047842GO:1990239
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH3 DNAH7 DYNC1H1

5.03e-0437843GO:0045505
GeneOntologyMolecularFunctionP-type sodium transporter activity

ATP1A1 ATP1A3

7.70e-0410842GO:0008554
GeneOntologyMolecularFunctionP-type sodium:potassium-exchanging transporter activity

ATP1A1 ATP1A3

7.70e-0410842GO:0005391
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

ABCC3 GABRQ GABRA3 XPR1 GABRA5

7.77e-04171845GO:0015103
GeneOntologyMolecularFunctionbenzodiazepine receptor activity

GABRA3 GABRA5

9.38e-0411842GO:0008503
GeneOntologyMolecularFunctionP-type potassium transmembrane transporter activity

ATP1A1 ATP1A3

9.38e-0411842GO:0008556
GeneOntologyMolecularFunctionATP-dependent activity

ABCC3 DNAH3 MYO1F MYO1B CHD4 ATP1A1 ATP1A3 DNAH7 DYNC1H1

1.10e-03614849GO:0140657
GeneOntologyMolecularFunctiondipeptidyl-peptidase activity

DPP4 DPP9

1.12e-0312842GO:0008239
GeneOntologyMolecularFunctionligand-gated monoatomic anion channel activity

GABRQ GABRA3 GABRA5

1.22e-0350843GO:0099095
GeneOntologyMolecularFunctionserine-type endopeptidase activity

DPP4 CORIN MMP9 PRSS58 F7

1.24e-03190845GO:0004252
GeneOntologyMolecularFunctionpeptidase activity

USP34 DPP4 DPP9 OTUD4 CORIN ERVK-10 MMP9 PRSS58 F7

1.70e-03654849GO:0008233
GeneOntologyMolecularFunctionendopeptidase activity

USP34 DPP4 CORIN ERVK-10 MMP9 PRSS58 F7

2.23e-03430847GO:0004175
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCC3 DNAH3 CHD4 ATP1A1 ATP1A3 DNAH7 DYNC1H1

2.57e-03441847GO:0016887
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GABRQ GABRA3 GABRA5

2.60e-0365843GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GABRQ GABRA3 GABRA5

2.60e-0365843GO:0022824
GeneOntologyMolecularFunctionL-ascorbic acid binding

PLOD3 PLOD2

3.16e-0320842GO:0031418
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH3 DNAH7 DYNC1H1

3.21e-0370843GO:0003777
GeneOntologyMolecularFunctionglucosyltransferase activity

PLOD3 PLOD2

3.82e-0322842GO:0046527
GeneOntologyMolecularFunctionankyrin binding

SPTBN4 ATP1A1

4.18e-0323842GO:0030506
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GABRQ GABRA3 GABRA5

4.20e-0377843GO:0005230
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GABRA3 GABRA5

4.54e-0324842GO:0099507
GeneOntologyBiologicalProcessgamma-aminobutyric acid signaling pathway

GABRQ ATP1A3 GABRA3 GABRA5

1.22e-0535844GO:0007214
GeneOntologyBiologicalProcesshydroxylysine biosynthetic process

PLOD3 PLOD2

1.64e-052842GO:0046947
GeneOntologyBiologicalProcesshydroxylysine metabolic process

PLOD3 PLOD2

1.64e-052842GO:0046946
GeneOntologyBiologicalProcessregulation of leukocyte migration

SELE DPP4 MYO1F C5 PTAFR MMP9 F7

1.09e-04267847GO:0002685
GeneOntologyBiologicalProcessviral process

CDK9 DPP4 LRSAM1 OASL OAS3 ERVK-10 HYAL2 XPR1 NEDD4

1.13e-04464849GO:0016032
GeneOntologyCellularComponentmicrovillus

MYO1F MYO1B CUBN CNP HYAL2 NEDD4

1.03e-05123846GO:0005902
GeneOntologyCellularComponentGABA-A receptor complex

GABRQ GABRA3 GABRA5

5.79e-0519843GO:1902711
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

STIM1 SPTBN4 DNAH3 DCDC2C DPP9 AVIL MYO1F MYO1B TUBGCP2 DNAH7 KRT36 DYNC1H1 CNP

5.83e-058998413GO:0099513
GeneOntologyCellularComponentGABA receptor complex

GABRQ GABRA3 GABRA5

7.90e-0521843GO:1902710
GeneOntologyCellularComponentphotoreceptor inner segment membrane

ATP1A1 ATP1A3

9.52e-054842GO:0060342
GeneOntologyCellularComponentcell cortex

SELE STIM1 SPTBN4 MYO1F MKLN1 DYNC1H1 SLC38A8 NEDD4

1.23e-04371848GO:0005938
GeneOntologyCellularComponentactin-based cell projection

MYO1F MYO1B CUBN DYNC1H1 CNP HYAL2 NEDD4

1.29e-04278847GO:0098858
GeneOntologyCellularComponentcell surface

SELE SEMA6C DPP4 DUOX1 ANOS1 TJP1 CD226 CORIN ROS1 CUBN ATP1A3 MDGA1 HYAL2

4.68e-0411118413GO:0009986
GeneOntologyCellularComponentintercellular canaliculus

DPP4 TJP1

5.64e-049842GO:0046581
GeneOntologyCellularComponentmembrane raft

SELE STIM1 DPP4 CD226 ATP1A1 MDGA1 HYAL2

6.36e-04362847GO:0045121
GeneOntologyCellularComponentmembrane microdomain

SELE STIM1 DPP4 CD226 ATP1A1 MDGA1 HYAL2

6.57e-04364847GO:0098857
GeneOntologyCellularComponentneuronal cell body membrane

TACR3 ATP1A3 GABRA5

6.88e-0443843GO:0032809
GeneOntologyCellularComponentinner dynein arm

DNAH3 DNAH7

7.03e-0410842GO:0036156
GeneOntologyCellularComponentsupramolecular fiber

STIM1 SPTBN4 DNAH3 DCDC2C DPP9 AVIL MYO1F MYO1B TUBGCP2 DNAH7 KRT36 DYNC1H1 CNP

8.16e-0411798413GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

STIM1 SPTBN4 DNAH3 DCDC2C DPP9 AVIL MYO1F MYO1B TUBGCP2 DNAH7 KRT36 DYNC1H1 CNP

8.69e-0411878413GO:0099081
GeneOntologyCellularComponentcell body membrane

TACR3 ATP1A3 GABRA5

8.93e-0447843GO:0044298
GeneOntologyCellularComponentcell leading edge

DPP4 DUOX1 DPP9 AVIL MKLN1 TACR3 GABRA3 GABRA5

8.99e-04500848GO:0031252
GeneOntologyCellularComponentsodium:potassium-exchanging ATPase complex

ATP1A1 ATP1A3

1.03e-0312842GO:0005890
GeneOntologyCellularComponenttrans-Golgi network membrane

NDST1 CLVS2 AP1M1 MYO1B

1.08e-03112844GO:0032588
GeneOntologyCellularComponentdynein complex

DNAH3 DNAH7 DYNC1H1

1.34e-0354843GO:0030286
GeneOntologyCellularComponentmicrotubule

STIM1 DNAH3 DCDC2C DPP9 TUBGCP2 DNAH7 DYNC1H1 CNP

1.35e-03533848GO:0005874
GeneOntologyCellularComponentdendrite membrane

TACR3 GABRA3 GABRA5

1.49e-0356843GO:0032590
GeneOntologyCellularComponentchloride channel complex

GABRQ GABRA3 GABRA5

1.57e-0357843GO:0034707
GeneOntologyCellularComponentPML body

CDK9 SPTBN4 MAGEA8 MAGEA11

1.63e-03125844GO:0016605
GeneOntologyCellularComponentrough endoplasmic reticulum

PLOD3 SEC63 PLOD2

2.19e-0364843GO:0005791
GeneOntologyCellularComponentintercalated disc

SPTBN4 TJP1 ATP1A1

2.60e-0368843GO:0014704
GeneOntologyCellularComponent9+2 motile cilium

DNAH3 DCDC2C TACR3 ATP1A1 DNAH7

2.73e-03238845GO:0097729
GeneOntologyCellularComponentactin filament

SPTBN4 AVIL MYO1F MYO1B

2.86e-03146844GO:0005884
GeneOntologyCellularComponentaxon

STIM1 SPTBN4 AVIL ADGRL1 DIXDC1 ATP1A1 ATP1A3 MDGA1 DYNC1H1 SLC38A8

2.99e-038918410GO:0030424
GeneOntologyCellularComponentGABA-ergic synapse

MKLN1 MDGA1 GABRA3 GABRA5

4.33e-03164844GO:0098982
GeneOntologyCellularComponentneuron projection membrane

TACR3 GABRA3 GABRA5

4.41e-0382843GO:0032589
GeneOntologyCellularComponentaxonemal dynein complex

DNAH3 DNAH7

4.51e-0325842GO:0005858
GeneOntologyCellularComponentapicolateral plasma membrane

TJP1 NEDD4

5.64e-0328842GO:0016327
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH7 DYNC1H1

2.97e-0514833IPR024317
DomainDynein_HC_stalk

DNAH3 DNAH7 DYNC1H1

2.97e-0514833IPR024743
DomainDynein_heavy_dom-2

DNAH3 DNAH7 DYNC1H1

2.97e-0514833IPR013602
DomainDHC_N2

DNAH3 DNAH7 DYNC1H1

2.97e-0514833PF08393
DomainMT

DNAH3 DNAH7 DYNC1H1

2.97e-0514833PF12777
DomainAAA_8

DNAH3 DNAH7 DYNC1H1

2.97e-0514833PF12780
DomainDHC_fam

DNAH3 DNAH7 DYNC1H1

3.70e-0515833IPR026983
DomainDynein_heavy_dom

DNAH3 DNAH7 DYNC1H1

3.70e-0515833IPR004273
DomainDynein_heavy

DNAH3 DNAH7 DYNC1H1

3.70e-0515833PF03028
DomainLYS_HYDROXYLASE

PLOD3 PLOD2

5.84e-053832PS01325
DomainProcol_lys_dOase

PLOD3 PLOD2

5.84e-053832IPR001006
DomainOAS1_C

OASL OAS3

1.16e-044832PF10421
Domain-

OASL OAS3

1.16e-0448321.10.1410.20
Domain25A_SYNTH_1

OASL OAS3

1.16e-044832PS00832
Domain25A_SYNTH_2

OASL OAS3

1.16e-044832PS00833
Domain2-5-oligoadenylate_synth_CS

OASL OAS3

1.16e-044832IPR006117
Domain25A_SYNTH_3

OASL OAS3

1.16e-044832PS50152
Domain2-5-oligoAdlate_synth_1_dom2/C

OASL OAS3

1.16e-044832IPR018952
Domain2-5A_synthase

OASL OAS3

1.16e-044832IPR026774
DomainGABAA/Glycine_rcpt

GABRQ GABRA3 GABRA5

1.41e-0423833IPR006028
Domain2-5-oligoadenylate_synth_N

OASL OAS3

1.93e-045832IPR006116
Domain-

DPP4 DPP9

2.89e-0468322.140.10.30
DomainDPPIV_N

DPP4 DPP9

2.89e-046832PF00930
DomainP-type_ATPase_IIC

ATP1A1 ATP1A3

2.89e-046832IPR005775
DomainGABAAa_rcpt

GABRA3 GABRA5

2.89e-046832IPR001390
DomainPeptidase_S9B_N

DPP4 DPP9

2.89e-046832IPR002469
DomainMyosin_TH1

MYO1F MYO1B

4.04e-047832PF06017
DomainMyosin_TH1

MYO1F MYO1B

4.04e-047832IPR010926
DomainTH1

MYO1F MYO1B

4.04e-047832PS51757
DomainPeptidase_S9

DPP4 DPP9

1.05e-0311832PF00326
DomainPeptidase_S9

DPP4 DPP9

1.05e-0311832IPR001375
DomainNeurotransmitter_ion_chnl_CS

GABRQ GABRA3 GABRA5

1.05e-0345833IPR018000
DomainNeur_chan_memb

GABRQ GABRA3 GABRA5

1.12e-0346833PF02932
DomainNeur_chan_LBD

GABRQ GABRA3 GABRA5

1.19e-0347833PF02931
DomainNEUROTR_ION_CHANNEL

GABRQ GABRA3 GABRA5

1.19e-0347833PS00236
DomainNeurotrans-gated_channel_TM

GABRQ GABRA3 GABRA5

1.19e-0347833IPR006029
Domain-

GABRQ GABRA3 GABRA5

1.19e-03478332.70.170.10
DomainNeur_channel

GABRQ GABRA3 GABRA5

1.19e-0347833IPR006201
DomainNeur_chan_lig-bd

GABRQ GABRA3 GABRA5

1.19e-0347833IPR006202
DomainATPase_dyneun-rel_AAA

DNAH3 DYNC1H1

1.72e-0314832IPR011704
DomainAAA_5

DNAH3 DYNC1H1

1.72e-0314832PF07728
Domain-

ATP1A1 ATP1A3

2.25e-03168321.20.1110.10
DomainP4Hc

PLOD3 PLOD2

2.25e-0316832SM00702
DomainPro_4_hyd_alph

PLOD3 PLOD2

2.25e-0316832IPR006620
DomainATPase_P-typ_TM_dom

ATP1A1 ATP1A3

2.25e-0316832IPR023298
DomainATPase_P-typ_cation-transptr_C

ATP1A1 ATP1A3

2.54e-0317832IPR006068
DomainCation_ATPase_C

ATP1A1 ATP1A3

2.54e-0317832PF00689
DomainCation_ATPase_N

ATP1A1 ATP1A3

2.85e-0318832PF00690
DomainCation_ATPase_N

ATP1A1 ATP1A3

2.85e-0318832SM00831
DomainATPase_P-typ_cation-transptr_N

ATP1A1 ATP1A3

3.18e-0319832IPR004014
Domain2OG-FeII_Oxy

PLOD3 PLOD2

3.18e-0319832PF03171
DomainMAGE_N

MAGEA8 MAGEA11

3.52e-0320832SM01392
DomainFE2OG_OXY

PLOD3 PLOD2

3.88e-0321832PS51471
DomainAAA+_ATPase

ABCC3 DNAH3 DNAH7 DYNC1H1

3.89e-03144834IPR003593
DomainAAA

ABCC3 DNAH3 DNAH7 DYNC1H1

3.89e-03144834SM00382
DomainMAGE_N

MAGEA8 MAGEA11

4.25e-0322832PF12440
DomainMAGE_N

MAGEA8 MAGEA11

4.25e-0322832IPR021072
DomainP-loop_NTPase

ABCC3 NDST1 DNAH3 TJP1 MYO1F MYO1B CHD4 DNAH7 DYNC1H1 CNP

4.28e-038488310IPR027417
Pubmed

Ectopic myelinating oligodendrocytes in the dorsal spinal cord as a consequence of altered semaphorin 6D signaling inhibit synapse formation.

SEMA6C AVIL CNP

2.80e-07685321831918
Pubmed

The NuRD chromatin-remodeling enzyme CHD4 promotes embryonic vascular integrity by transcriptionally regulating extracellular matrix proteolysis.

TJP1 CHD4 MMP9

2.29e-061185324348274
Pubmed

Retinal pigment epithelial integrity is compromised in the developing albino mouse retina.

TJP1 ATP1A1 ATP1A3

3.05e-061285327097562
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH3 DNAH7 DYNC1H1

5.03e-06148539373155
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

DPP4 TJP1 OTUD4 OAS3 MYO1B ROS1 CHD4 C5 ATP1A1 SEC63 PLOD2 DYNC1H1 CNP MTFMT

5.68e-061371851436244648
Pubmed

Regulated inositol-requiring protein 1-dependent decay as a mechanism of corin RNA and protein deficiency in advanced human systolic heart failure.

ERN1 CORIN

5.90e-06285225516437
Pubmed

GABA-A receptor beta3 and alpha5 subunit gene cluster on chromosome 15q11-q13 and bipolar disorder: a genetic association study.

GABRA3 GABRA5

5.90e-06285211378843
Pubmed

Functional epistatic interaction between rs6046G>A in F7 and rs5355C>T in SELE modifies systolic blood pressure levels.

SELE F7

5.90e-06285222815813
Pubmed

Serum E-selectin and erythrocyte membrane Na+K+ ATPase levels in patients with rheumatoid arthritis.

SELE ATP1A1

5.90e-06285215515123
Pubmed

All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides.

ATP1A1 ATP1A3

5.90e-06285211546672
Pubmed

Properties and expression of Na+/K+-ATPase α-subunit isoforms in the brain of the swamp eel, Monopterus albus, which has unusually high brain ammonia tolerance.

ATP1A1 ATP1A3

5.90e-06285224391932
Pubmed

The ER stress sensor IRE1 interacts with STIM1 to promote store-operated calcium entry, T cell activation, and muscular differentiation.

STIM1 ERN1

5.90e-06285238060449
Pubmed

Na+/K+ ATPase α1 and α3 isoforms are differentially expressed in α- and γ-motoneurons.

ATP1A1 ATP1A3

5.90e-06285223761886
Pubmed

The family of human Na+,K+-ATPase genes. A partial nucleotide sequence related to the alpha-subunit.

ATP1A1 ATP1A3

5.90e-0628523030810
Pubmed

Analysis of the effects of rare variants on splicing identifies alterations in GABAA receptor genes in autism spectrum disorder individuals.

GABRQ GABRA3

5.90e-06285223169495
Pubmed

Role of a propeller loop in the quaternary structure and enzymatic activity of prolyl dipeptidases DPP-IV and DPP9.

DPP4 DPP9

5.90e-06285222001206
Pubmed

Cubilin Single Nucleotide Polymorphism Variants are Associated with Macroangiopathy While a Matrix Metalloproteinase-9 Single Nucleotide Polymorphism Flip-Flop may Indicate Susceptibility of Diabetic Nephropathy in Type-2 Diabetic Patients.

CUBN MMP9

5.90e-06285230557881
Pubmed

Immunohistochemical analyses of alpha1 and alpha3 Na+/K+-ATPase subunit expression in medulloblastomas.

ATP1A1 ATP1A3

5.90e-06285221498719
Pubmed

Plasma levels of DPP4 activity and sDPP4 are dissociated from inflammation in mice and humans.

GIPR DPP4

5.90e-06285232724076
Pubmed

Complete genomic structure of mouse lysyl hydroxylase 2 and lysyl hydroxylase 3/collagen glucosyltransferase.

PLOD3 PLOD2

5.90e-06285211334715
Pubmed

Pathogenic mechanisms in varicose vein disease: the role of hypoxia and inflammation.

SELE EPAS1

5.90e-06285220632821
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

USP34 DPP4 UTP15 LMBR1 DIXDC1 ATP1A1 DNAH7 GABRA3

9.05e-0642085828065597
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

CDK9 PLOD3 UTP15 TJP1 OASL AP1M1 OAS3 MYO1B TUBGCP2 SEC63 DYNC1H1 CNP CEP55

1.11e-051257851336526897
Pubmed

Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.

GABRQ GABRA3 GABRA5

1.12e-051885319078961
Pubmed

Loss of Rab6a in the small intestine causes lipid accumulation and epithelial cell death from lactation.

DPP4 TJP1 ATP1A1

1.12e-051885332496646
Pubmed

Anterograde trafficking signals in GABAA subunits are required for functional expression.

GABRQ GABRA3

1.77e-05385231610743
Pubmed

Three differentially expressed Na,K-ATPase alpha subunit isoforms: structural and functional implications.

ATP1A1 ATP1A3

1.77e-0538522822726
Pubmed

Interplay between the Chd4/NuRD Complex and the Transcription Factor Znf219 Controls Cardiac Cell Identity.

CORIN CHD4

1.77e-05385236076959
Pubmed

Isoforms of dipeptidyl aminopeptidase IV from Pseudomonas sp. WO24: role of the signal sequence and overexpression in Escherichia coli.

DPP4 DPP9

1.77e-05385215866709
Pubmed

The effect of CD26-deficiency on dipeptidyl peptidase 8 and 9 expression profiles in a mouse model of Crohn's disease.

DPP4 DPP9

1.77e-05385229693275
Pubmed

Identification of a VxP Targeting Signal in the Flagellar Na+ /K+ -ATPase.

ATP1A1 ATP1A3

1.77e-05385226373354
Pubmed

GABRA3 promotes lymphatic metastasis in lung adenocarcinoma by mediating upregulation of matrix metalloproteinases.

MMP9 GABRA3

1.77e-05385227081042
Pubmed

Differential expression of Na+/K+-ATPase alpha-subunits in mouse hippocampal interneurones and pyramidal cells.

ATP1A1 ATP1A3

1.77e-05385217947306
Pubmed

Characterization of cDNAs for mouse lysyl hydroxylase 1, 2 and 3, their phylogenetic analysis and tissue-specific expression in the mouse.

PLOD3 PLOD2

1.77e-05385210429951
Pubmed

Identification of amino acids important for the catalytic activity of the collagen glucosyltransferase associated with the multifunctional lysyl hydroxylase 3 (LH3).

PLOD3 PLOD2

1.77e-05385211896059
Pubmed

Characterization of three fragments that constitute the monomers of the human lysyl hydroxylase isoenzymes 1-3. The 30-kDa N-terminal fragment is not required for lysyl hydroxylase activity.

PLOD3 PLOD2

1.77e-05385211956192
Pubmed

Knockout of sodium pump α3 subunit gene (Atp1a3-/-) results in perinatal seizure and defective respiratory rhythm generation.

ATP1A1 ATP1A3

1.77e-05385228465228
Pubmed

Lysyl hydroxylase 3 is a multifunctional protein possessing collagen glucosyltransferase activity.

PLOD3 PLOD2

1.77e-05385210934207
Pubmed

Primary structure, tissue distribution, and chromosomal localization of a novel isoform of lysyl hydroxylase (lysyl hydroxylase 3).

PLOD3 PLOD2

1.77e-0538529582318
Pubmed

Na,K-ATPase and the role of alpha isoforms in behavior.

ATP1A1 ATP1A3

1.77e-05385218044013
Pubmed

Glycoprotein nonmetastatic melanoma protein B extracellular fragment shows neuroprotective effects and activates the PI3K/Akt and MEK/ERK pathways via the Na+/K+-ATPase.

ATP1A1 ATP1A3

1.77e-05385226988030
Pubmed

The lysyl hydroxylase isoforms are widely expressed during mouse embryogenesis, but obtain tissue- and cell-specific patterns in the adult.

PLOD3 PLOD2

1.77e-05385216996725
Pubmed

An αII Spectrin-Based Cytoskeleton Protects Large-Diameter Myelinated Axons from Degeneration.

AVIL CNP

1.77e-05385229038243
Pubmed

Extraenzymatic functions of the dipeptidyl peptidase IV-related proteins DP8 and DP9 in cell adhesion, migration and apoptosis.

DPP4 DPP9

1.77e-05385216704418
Pubmed

The genes encoding mouse lysyl hydroxylase isoforms map to chromosomes 4,5, and 9.

PLOD3 PLOD2

1.77e-05385211130984
Pubmed

Na+/K+-ATPase α isoform deficiency results in distinct spreading depolarization phenotypes.

ATP1A1 ATP1A3

1.77e-05385230819023
Pubmed

Glycoprotein nonmetastatic melanoma protein B (GPNMB) promotes the progression of brain glioblastoma via Na+/K+-ATPase.

ATP1A1 ATP1A3

1.77e-05385227836549
Pubmed

Association between sodium- and potassium-activated adenosine triphosphatase alpha isoforms and bipolar disorders.

ATP1A1 ATP1A3

1.77e-05385219058785
Pubmed

Procollagen-lysine, 2-oxoglutarate 5-dioxygenases 1, 2, and 3 are potential prognostic indicators in patients with clear cell renal cell carcinoma.

PLOD3 PLOD2

1.77e-05385231446433
Pubmed

Developmental cell-specific regulation of Na(+)-K(+)-ATPase alpha 1-, alpha 2-, and alpha 3-isoform gene expression.

ATP1A1 ATP1A3

1.77e-0538528203495
Pubmed

Cyclin-dependent kinase 9 is required for tumor necrosis factor-alpha-stimulated matrix metalloproteinase-9 expression in human lung adenocarcinoma cells.

CDK9 MMP9

1.77e-05385215528190
Pubmed

HIV-1 Tat-induced cerebrovascular toxicity is enhanced in mice with amyloid deposits.

TJP1 MMP9

1.77e-05385221764480
Pubmed

Glial βII Spectrin Contributes to Paranode Formation and Maintenance.

AVIL CNP

1.77e-05385229853631
Pubmed

Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis.

DPP4 DPP9

1.77e-05385223608773
Pubmed

Recruitment of Matrix Metalloproteinase-9 (MMP-9) to the Fibroblast Cell Surface by Lysyl Hydroxylase 3 (LH3) Triggers Transforming Growth Factor-β (TGF-β) Activation and Fibroblast Differentiation.

PLOD3 MMP9

1.77e-05385225825495
Pubmed

Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model.

ATP1A1 ATP1A3

1.77e-05385226911348
Pubmed

The complement component C5a is present in human coronary lesions in vivo and induces the expression of MMP-1 and MMP-9 in human macrophages in vitro.

C5 MMP9

1.77e-05385220813982
Pubmed

Cardiac glycosides induced toxicity in human cells expressing α1-, α2-, or α3-isoforms of Na-K-ATPase.

ATP1A1 ATP1A3

1.77e-05385225994790
Pubmed

Nodal β spectrins are required to maintain Na+ channel clustering and axon integrity.

SPTBN4 AVIL

1.77e-05385232052742
Pubmed

Early growth response 1 (Egr-1) directly regulates GABAA receptor α2, α4, and θ subunits in the hippocampus.

GABRQ GABRA3 GABRA5

1.82e-052185325708312
Pubmed

Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.

TJP1 MYO1B ATP1A1 ATP1A3 DYNC1H1

2.85e-0514485535681168
Pubmed

Increased susceptibility to cortical spreading depression in the mouse model of familial hemiplegic migraine type 2.

ATP1A1 ATP1A3

3.53e-05485221731499
Pubmed

The Na,K-ATPase alpha 2 isoform is expressed in neurons, and its absence disrupts neuronal activity in newborn mice.

ATP1A1 ATP1A3

3.53e-05485212458206
Pubmed

Gene structure of the murine 2'-5'-oligoadenylate synthetase family.

OASL OAS3

3.53e-05485212222967
Pubmed

Angiopoietin-2 facilitates vascular endothelial growth factor-induced angiogenesis in the mature mouse brain.

TJP1 MMP9

3.53e-05485215947259
Pubmed

Expression of dipeptidyl peptidase-IV activity and/or structure homologs in human meningiomas.

DPP4 DPP9

3.53e-05485220043068
Pubmed

Glycosylation catalyzed by lysyl hydroxylase 3 is essential for basement membranes.

PLOD3 PLOD2

3.53e-05485216467571
Pubmed

Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia.

ATP1A1 ATP1A3

3.53e-05485221849490
Pubmed

Sec63 and Xbp1 regulate IRE1α activity and polycystic disease severity.

ERN1 SEC63

3.53e-05485225844898
Pubmed

Axon Initial Segments Are Required for Efficient Motor Neuron Axon Regeneration and Functional Recovery of Synapses.

SPTBN4 AVIL

3.53e-05485236096668
Pubmed

Variability in the 2'-5'-oligoadenylate synthetase gene cluster is associated with human predisposition to tick-borne encephalitis virus-induced disease.

OASL OAS3

3.53e-05485221050126
Pubmed

Quantitative evaluation of the expression of MAGE genes in tumors by limiting dilution of cDNA libraries.

MAGEA8 MAGEA11

3.53e-05485210521804
Pubmed

Positive Regulation of Transcription by Human ZMYND8 through Its Association with P-TEFb Complex.

CDK9 CHD4

3.53e-05485230134174
Pubmed

Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABAA receptor subtype.

GABRA3 GABRA5

3.53e-05485225865415
Pubmed

Muscle Na+-K+-ATPase activity and isoform adaptations to intense interval exercise and training in well-trained athletes.

ATP1A1 ATP1A3

3.53e-05485217446412
Pubmed

Impact of epsilon and theta subunits on pharmacological properties of alpha3beta1 GABAA receptors expressed in Xenopus oocytes.

GABRQ GABRA3

3.53e-05485216412217
Pubmed

Na,K-ATPase expression in the mouse cochlea is not dependent on the mineralocorticoid receptor.

ATP1A1 ATP1A3

3.53e-05485211591489
Pubmed

PLODs are overexpressed in ovarian cancer and are associated with gap junctions via connexin 43.

PLOD3 PLOD2

3.53e-05485233483598
Pubmed

Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity.

LRSAM1 LRRC2

3.53e-05485220616063
Pubmed

Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase alpha1beta1, alpha2beta1 and alpha3beta1.

ATP1A1 ATP1A3

3.53e-05485219751721
Pubmed

Agrin regulation of alpha3 sodium-potassium ATPase activity modulates cardiac myocyte contraction.

ATP1A1 ATP1A3

3.53e-05485219376779
Pubmed

Altered GABA(A) receptor subunit expression and pharmacology in human Angelman syndrome cortex.

GABRA3 GABRA5

3.53e-05485220692323
Pubmed

The Sec61 translocon limits IRE1α signaling during the unfolded protein response.

ERN1 SEC63

3.53e-05485228504640
Pubmed

Deficiency in Na,K-ATPase alpha isoform genes alters spatial learning, motor activity, and anxiety in mice.

ATP1A1 ATP1A3

3.53e-05485217234593
Pubmed

Family of Na+,K+-ATPase genes. Intra-individual tissue-specific restriction fragment length polymorphism.

ATP1A1 ATP1A3

3.53e-0548522887455
Pubmed

Roles and functions of HIV-1 Tat protein in the CNS: an overview.

CDK9 TJP1 MMP9

3.95e-052785324359561
Pubmed

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.

TJP1 OTUD4 ADGRL1 TUBGCP2 PLOD2 CNP XPR1

4.04e-0537885734315543
Pubmed

Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.

GABRQ TACR3 GABRA3 GABRA5

4.79e-058185422723691
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

STIM1 USP34 PLOD3 DPP9 TJP1 DHRS7 OAS3 CHD4 ACAD10 ATP1A1 SEC63 PLOD2 NEDD4

4.95e-051451851330550785
Pubmed

Nsp2 has the potential to be a drug target revealed by global identification of SARS-CoV-2 Nsp2-interacting proteins.

CDK9 DPH1 KLHL42 PLOD2

5.52e-058485434159380
Pubmed

The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities.

OASL OAS3

5.87e-05585221142819
Pubmed

Multiple genes encode the human Na+,K+-ATPase catalytic subunit.

ATP1A1 ATP1A3

5.87e-0558523035563
Pubmed

Mechanism of blood-retinal barrier breakdown induced by HIV-1 (Review).

TJP1 MMP9

5.87e-05585224660027
Pubmed

The clathrin adaptor complex AP-1 binds HIV-1 and MLV Gag and facilitates their budding.

AP1M1 NEDD4

5.87e-05585217538020
Pubmed

Itch suppression in mice and dogs by modulation of spinal α2 and α3GABAA receptors.

GABRA3 GABRA5

5.87e-05585230104684
Pubmed

Genetic risk for restenosis after coronary stenting.

ROS1 MMP9

5.87e-05585217275003
Pubmed

Genomic structure of the mouse 2',5'-oligoadenylate synthetase gene family.

OASL OAS3

5.87e-05585212396720
Pubmed

Matrix metalloproteinase-2 and -9 secreted by leukemic cells increase the permeability of blood-brain barrier by disrupting tight junction proteins.

TJP1 MMP9

5.87e-05585221857898
Pubmed

Expression and prognostic assessment of dipeptidyl peptidase IV and related enzymes in B-cell chronic lymphocytic leukemia.

DPP4 DPP9

5.87e-05585220534982
Pubmed

CHD4 Promotes Breast Cancer Progression as a Coactivator of Hypoxia-Inducible Factors.

CHD4 EPAS1

5.87e-05585232699137
CytobandXq28

MAGEA8 MAGEA11 GABRQ GABRA3

3.32e-04176854Xq28
Cytoband12q24.2

OASL OAS3

4.00e-041685212q24.2
CytobandEnsembl 112 genes in cytogenetic band chrXq28

MAGEA8 MAGEA11 GABRQ GABRA3

6.80e-04213854chrXq28
Cytoband3q24

PLOD2 HPS3

1.52e-03318523q24
GeneFamilyGamma-aminobutyric acid type A receptor subunits

GABRQ GABRA3 GABRA5

3.75e-0519633563
GeneFamilyATPase Na+/K+ transporting subunits

ATP1A1 ATP1A3

2.48e-0476321208
GeneFamilyCD molecules|DASH family

DPP4 DPP9

2.48e-0476321205
GeneFamilyMyosins, class I

MYO1F MYO1B

3.30e-0486321097
GeneFamilyDyneins, axonemal

DNAH3 DNAH7

1.57e-0317632536
CoexpressionGSE37534_GW1929_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_UP

ABCC3 MAGEA8 OASL OAS3 CHD4 GPA33 CNP

3.50e-06198847M8985
CoexpressionCROMER_TUMORIGENESIS_UP

PLOD3 OASL MYO1B MMP9

3.65e-0558844M178
CoexpressionNABA_MATRISOME_PRIMARY_METASTATIC_COLORECTAL_TUMOR

PLOD3 COL22A1 MMP9 PLOD2

3.91e-0559844M47989
CoexpressionGSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_DN

STIM1 ABCC3 DPP4 PLOD2 GPA33 PEX26

4.17e-05197846M3472
CoexpressionMCBRYAN_PUBERTAL_BREAST_6_7WK_UP

ABCC3 NDST1 LRATD1 CHD4 ATP1A3 EPAS1

4.41e-05199846MM991
CoexpressionMCBRYAN_PUBERTAL_BREAST_6_7WK_UP

ABCC3 NDST1 LRATD1 CHD4 ATP1A3 EPAS1

4.41e-05199846M2155
CoexpressionGSE17721_CPG_VS_GARDIQUIMOD_6H_BMDC_DN

USP34 MYO1F KLHL42 LMBR1 CEP55 XPR1

4.54e-05200846M3891
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma-osteoclast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

GIPR DPP4 MYO1B DIXDC1 MMP9 HYAL2

1.52e-06188846762b52f21d2bc5409f86746a904c4358490be9c0
ToppCellNS-critical-d_0-4-Lymphoid-NK|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DPP9 MYO1B DIXDC1 DYNC1H1 HYAL2 MTFMT

1.77e-061938461b29525c5936d1b779253b8c20f059fa091c6127
ToppCellASK440-Epithelial-Type_2|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

DPP4 DUOX1 GKN2 MYO1B ROS1 ATP1A1

1.94e-06196846754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCellP03-Hematopoietic-Immune-immune_cell_unspecified|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD226 MYO1F PTAFR ATP1A3 GPR132

9.31e-0614984543d756f81d532b5c7f2306e6af9d072d496cbc8e
ToppCellP03-Hematopoietic-Immune|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD226 MYO1F PTAFR ATP1A3 GPR132

9.31e-061498451c5a2572741c47246d455c865e8e1677c9f49598
ToppCellfacs-Aorta-Heart-18m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLVS2 MYO1F ATP1A3 F7 GPR132

1.16e-051568455b56217336771baf57d791efcb4e206c6aea83b1
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

GIPR NDST1 UTP15 OAS3 DNAH7

1.16e-05156845abea3c183d32062b009a79a2bdf861021989c7ef
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

GIPR NDST1 OAS3 DNAH7 NEDD4

1.53e-05165845436ce4bc75e1ba4351c439ccad19f84ad5bcb92f
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

GIPR NDST1 OAS3 DNAH7 NEDD4

1.53e-05165845242bdb7654f415391fb8e9bdc06412c7eee9c97e
ToppCelldroplet-Bladder-BLADDER-1m-Hematologic-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP4 CD226 ATP1A3 GPR132 CEP55

1.57e-051668458e5a262dc4f04c5fc75b9a7a907832a0d7877df0
ToppCelldroplet-Bladder-nan-3m-Hematologic-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP4 CD226 MYO1F ATP1A3 GPR132

1.57e-05166845e01c720de6d4ca144c55378e023e718a64bf32f6
ToppCellfacs-Trachea-nan-24m-Myeloid-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1F PTAFR ATP1A3 MMP9 GPR132

1.71e-0516984587e95804b3b19c245cea6293d72b64351293b0e8
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1F ATP1A3 PLOD2 F7 GPR132

1.92e-051738457456a417c5c1d4ba25f9489065aae322421308a6
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1F ATP1A3 PLOD2 F7 GPR132

1.92e-0517384535586a9e5f15b41609b6224e33eb3aa3cb7e03b7
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Hematologic|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1F ATP1A3 PLOD2 F7 GPR132

1.92e-05173845cd635751f999e12b14c0accfa1c4c1fd3c1d4540
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPP4 ROS1 BEND4 MDGA1 GABRA5

1.97e-051748457d4b860e05b5931f6f9d757a68f75ff35597a47a
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPP4 ROS1 BEND4 MDGA1 GABRA5

2.08e-05176845ed421d8525108d2f585265d2cf777f07b29f44f0
ToppCell15-Airway-Immune-Hematopoietic,_Natural_Killer_Cell|Airway / Age, Tissue, Lineage and Cell class

CD226 MYO1F OASL MMP9 GPA33

2.20e-051788450003c3f2561b7a1fd86772bcba59883ba1f17cd2
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SELE TJP1 CUBN EPAS1 HYAL2

2.57e-05184845087666ba949b129c53d7ace40f9e543e3875a7de
ToppCellmetastatic_Brain-Endothelial_cells-Stalk-like_ECs|metastatic_Brain / Location, Cell class and cell subclass

DOCK1 DIXDC1 CUBN EPAS1 HYAL2

2.64e-05185845ad52970e88e8947ef256095bd4b40229b912d58a
ToppCellIPF-Epithelial-ATII|IPF / Disease state, Lineage and Cell class

DPP4 DUOX1 GKN2 MYO1B ROS1

2.64e-05185845563b4e6d92bb5d77a3829556116a8e99aebac615
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma-osteoclast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GIPR DPP4 MYO1B DIXDC1 MMP9

2.64e-051858455ed49b6d8214c6119355a6d3ee4e25d40bcc0c53
ToppCellIPF-Epithelial-ATII|World / Disease state, Lineage and Cell class

DPP4 DUOX1 GKN2 MYO1B ROS1

2.71e-051868456a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCell10x5'v1-week_12-13-Myeloid_macrophage-stroma-osteoclast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

DPP4 MYO1B DIXDC1 MMP9 XPR1

2.71e-05186845c9dfcf7bba7e5ef97ad5d9b7084fba932c91ab68
ToppCellHippocampus-Neuronal|Hippocampus / BrainAtlas - Mouse McCarroll V32

SPTBN4 USP34 CLVS2 ADGRL1 ATP1A3

3.32e-051948458aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 ABCC3 DPP4 PTAFR GPR132

3.40e-05195845938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)|356C / Donor, Lineage, Cell class and subclass (all cells)

NDST1 ANOS1 TJP1 MYO1B MDGA1

3.40e-0519584507a3ef6b0f1201fe2bcb9ea426b8f7a69beb4904
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-Trm_Th1/Th17|lymph-node_spleen / Manually curated celltypes from each tissue

DPP4 ERN1 CD226 OASL EPAS1

3.40e-05195845c60982804a74dbe6607c021799ca74af2204aba8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 ABCC3 DPP4 PTAFR GPR132

3.40e-05195845d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)-|356C / Donor, Lineage, Cell class and subclass (all cells)

NDST1 ANOS1 TJP1 MYO1B MDGA1

3.40e-05195845b65511770ed67f7447847e2187555b362988af45
ToppCellChildren_(3_yrs)-Endothelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

DCDC2C LRATD1 EPAS1 HYAL2 NEDD4

3.40e-05195845094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCellASK454-Endothelial-Endothelium|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

SELE DOCK1 LRATD1 EPAS1 HYAL2

3.48e-051968452b777a2026b56839112fd179f2db482c49f4594a
ToppCellcellseq-Epithelial-Epithelial_Alveolar|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DUOX1 GKN2 MYO1B ROS1 ATP1A1

3.48e-05196845a7cbe66ebd8931ef2b8ff26a42afce0ad1c48f17
ToppCellCOPD-Lymphoid-T|Lymphoid / Disease state, Lineage and Cell class

DPP4 ERN1 CD226 MYO1B GPR132

3.48e-05196845c9bdd505c3ab380ed7b272aa518df31a0a706a06
ToppCellASK440-Epithelial-Type_2|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

DPP4 DUOX1 GKN2 ROS1 ATP1A1

3.57e-0519784508d5bbeb77a4152af1c783bc958afcae24667767
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SELE TJP1 PTAFR EPAS1 HYAL2

3.57e-051978457a1a3839b2c965136663241b0d4e96c64cfb656a
ToppCellnormal_Lung-Endothelial_cells-Stalk-like_ECs|normal_Lung / Location, Cell class and cell subclass

SELE TJP1 DIXDC1 EPAS1 HYAL2

3.65e-051988452a251d13c2488d15ca9b11e643c1d17d428b6ef0
ToppCellAT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

DUOX1 SLC44A1 GKN2 ROS1 ATP1A1

3.65e-05198845893036558a9ad86b57f9e735df35812e9d18739e
ToppCellILEUM-non-inflamed-(7)_ACKR1+_endothelial_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SELE TJP1 DIXDC1 EPAS1 HYAL2

3.65e-05198845f8a6a75c9f2fbe32a22b14b6a029411c73c09f68
ToppCellBiopsy_Other_PF-Epithelial-AT2|Biopsy_Other_PF / Sample group, Lineage and Cell type

DPP4 DUOX1 GKN2 MYO1B ROS1

3.74e-051998459a65acfe9bf500db72142469cf17bf0973540001
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-CD4_TRM/EMRA|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DPP4 CD226 MYO1F OASL ATP1A3

3.74e-051998455a29db2610ba06a2248325a16cad755d20debf2c
ToppCellBiopsy_IPF-Epithelial-Transitional_AT2|Biopsy_IPF / Sample group, Lineage and Cell type

DPP4 ANOS1 GKN2 MYO1B ROS1

3.74e-0519984583ff8b7e472d1212324c05cc719b746d19e5e23b
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPP4 DUOX1 ROS1 C5 ATP1A1

3.74e-051998452dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TJP1 EPAS1 DYNC1H1 HYAL2 NEDD4

3.83e-0520084572ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TJP1 OAS3 EPAS1 HYAL2 NEDD4

3.83e-05200845bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DUOX1 TJP1 LRATD1 ATP1A1 EPAS1

3.83e-0520084597f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TJP1 EPAS1 DYNC1H1 HYAL2 NEDD4

3.83e-052008455c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

TJP1 OAS3 EPAS1 DYNC1H1 NEDD4

3.83e-0520084589821a264e872ed53e08e9d3609d5cc5c314503e
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DPP4 DUOX1 GKN2 ROS1 ATP1A1

3.83e-05200845acc771a902cf2f060c3eb9aedb72a256f5778a6c
ToppCellParenchyma_COVID-19-Epithelial-TX-AT2-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

DPP4 DUOX1 GKN2 ROS1 ATP1A1

3.83e-05200845ceb613ac6cdf0e3e6bb3f04d89034e18a524cefb
ToppCellControl_saline-Endothelial-Endothelial-Activated_Alv_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

TJP1 OAS3 EPAS1 DYNC1H1 NEDD4

3.83e-05200845be55cef682ba87250dad97689332c8820b3a7420
ToppCellControl_saline-Endothelial-Endothelial-Alv_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

ABCC3 TJP1 EPAS1 HYAL2 NEDD4

3.83e-05200845abf4ba5fcb54cdeada0da1a8b956a30aa47679e4
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

TJP1 OAS3 EPAS1 HYAL2 NEDD4

3.83e-052008453585484c7e24e941708bee471ca607d8ccee74e6
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DUOX1 TJP1 LRATD1 ATP1A1 EPAS1

3.83e-05200845ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DPP4 DUOX1 GKN2 ROS1 ATP1A1

3.83e-05200845eb44d1f80ecaac3a022cd04ab16dc36151e45488
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Interneuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

STIM1 DNAH3 BEND4 CUBN

8.13e-05121844b2d571f571133c281d72584fe925cebbd2317829
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPTBN4 MYO1F ATP1A3 MMP9

1.59e-041448441efa434e577d1f87e02df01667782f414d63bd60
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPTBN4 MYO1F ATP1A3 MMP9

1.59e-04144844c0c5f254a960ba5e5f1354599d54e77360e6c2ac
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO1F OAS3 ATP1A3 MMP9

1.63e-04145844ab0e254a8d01021619853a6c175f620ccef217d8
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYO1F OAS3 ATP1A3 MMP9

1.63e-041458442beb4ea3838796c580076ab7769de877a3a0552c
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Sema3c_(Deep_layer_pyramidal_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

DUOX1 PADI6 SLC38A8

1.71e-04578438b0990dad1dac9ab898db47a10e652c753012f4b
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Sema3c_(Deep_layer_pyramidal_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

DUOX1 PADI6 SLC38A8

1.71e-0457843a31e226e26fd621df88a855ca899eea046fe0b71
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P1|Thalamus / BrainAtlas - Mouse McCarroll V32

SLC44A1 CORIN GSTO2 CNP

1.72e-04147844a21b63d0d3aec9ffadf3fac833a0a24da58a95bf
ToppCellfacs-Skin-nan-18m-Myeloid-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1F OAS3 MMP9 F7

1.81e-0414984423a1b95c12f2e3708dc003e13fab423e89821f11
ToppCellfacs-Skin-nan-18m-Myeloid-macrophage|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1F OAS3 MMP9 F7

1.81e-04149844c53a3226adc8fd0eaaa842b6a96442287580cbe0
ToppCellfacs-Skin-nan-18m-Myeloid|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1F OAS3 MMP9 F7

1.81e-04149844bb18a18b891af85849b9658d774053f839c9a8e1
ToppCellfacs-Brain_Myeloid-Cerebellum_-18m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP4 BEND4 MMP9 GPR132

1.91e-041518443105b8c0c401faa92e1ab8223d435b21ed45c5b7
ToppCellmild_COVID-19_(asymptomatic)-MAIT|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

SPTBN4 SEMA6C DPP4 ERN1

2.01e-0415384426852f3d8f80e102e24bcb90e24aac26fdc9a32c
ToppCellCV-Healthy-3|Healthy / Virus stimulation, Condition and Cluster

MKLN1 KLHL42 ACAD10 EPAS1

2.06e-0415484426bf81a86700db7e65c2384ffe94ed4253ea4047
ToppCellAT1-AT2_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

SEMA6C ANOS1 CORIN C5

2.11e-04155844010e45ef4b505bf419ea41e4d1619521d1c78319
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT2_Precursor|E16.5-samps / Age Group, Lineage, Cell class and subclass

GIPR DPP4 GKN2 ROS1

2.11e-041558449cad73d0b8ead289e1073d1a2e00bbeb1228308c
ToppCellfacs-Lung-EPCAM-24m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUOX1 ATP1A3 MMP9 GPA33

2.22e-04157844d2cb261a9ee2c90e2e0fc656bd6413fbccb465fc
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DUOX1 ATP1A3 MMP9 GPA33

2.22e-04157844350069e4d2dbddc82e813e2a2cc43032daa23605
ToppCellsevere_COVID-19-MAIT|severe_COVID-19 / disease group, cell group and cell class (v2)

SPTBN4 DPP4 ERN1 F7

2.22e-04157844175f637e9707836bd63b5c2ccc9d4eb601c05b9e
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLVS2 LRSAM1 OAS3 ATP1A3

2.27e-04158844b0508a600994090c6aafd8d779437190a33ad821
ToppCellfacs-Heart-RV-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1F OAS3 ATP1A3 MMP9

2.27e-041588442a222301474c4dfd9a776e197c10f4c1cacceb62
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

ABCC3 DNAH3 CORIN ROS1

2.27e-04158844ab05f6d7968ccd6d3826cd71b763dbedc83822c3
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AVIL LRATD1 MMP9 HPS3

2.27e-041588446d2709b387945c015faa223c20d22b52a4082140
ToppCellfacs-Lung-EPCAM-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLVS2 LRSAM1 OAS3 ATP1A3

2.27e-04158844a816cc095452308d06f87b77467e2a8c6361fd2a
ToppCellfacs-Heart-RV-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1F OAS3 ATP1A3 MMP9

2.27e-04158844ff9878fd768f22bf2ee4805bac2ba01cb3cb804a
ToppCelldroplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPTBN4 ABCC3 PTAFR MMP9

2.27e-041588449a6d9b541446a6aa9f8ed040b330dbb5c6447076
ToppCelldroplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPTBN4 ABCC3 PTAFR MMP9

2.27e-041588442438713d2a7e32c647ab3384237ed614f4ec8fec
ToppCellfacs-Lung-nan-3m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1F OASL ATP1A3 MMP9

2.33e-04159844836c4b5f9a714ffb5a449087ebefdbb37dd3a2a9
ToppCell18-Airway-Epithelial-Bud_tip_progenitor|Airway / Age, Tissue, Lineage and Cell class

DPP4 ROS1 TACR3 C5

2.33e-04159844e715cadff8e7d5ebe4c2198dbdfd3ca41ecb8a6a
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

ERN1 GKN2 C5 GSTO2

2.33e-04159844af137688e06a97ff97bb7def54f0dd164d155b11
ToppCellfacs-Lung-nan-3m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1F OASL ATP1A3 MMP9

2.33e-04159844a6742ba2216427409173aec4e05a537d7fde226c
ToppCellfacs-MAT-Fat-18m-Myeloid-myeloid_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1F PTAFR ATP1A3 MMP9

2.38e-04160844bd5fa7959bfe81011b8d798535b73ea1eee008b3
ToppCellCV-Healthy-3|CV / Virus stimulation, Condition and Cluster

MKLN1 ACAD10 GPR132 EPAS1

2.44e-04161844fd4a79385ea967b9900dc76a3add813b894a3a28
ToppCellfacs-MAT-Fat-24m-Myeloid-myeloid_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 MYO1F ATP1A3 MMP9

2.44e-0416184465888250b8c1da6a8f9b5376e086a3769a1cbbd8
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 AVIL MYO1B GPA33

2.50e-041628443dc39db0d5f6f3d7bcc312a6bce7aaeb914138d1
ToppCellfacs-Thymus-Epithelium-3m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 AVIL MYO1B GPA33

2.50e-041628440a7138266054ea5954649c8b61ef93905d56b068
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 AVIL MYO1B GPA33

2.50e-0416284425323785dd33337bcefd05958a4a1a208a9ceb04
ToppCellfacs-MAT-Fat-3m-Myeloid-myeloid_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1F PTAFR ATP1A3 MMP9

2.56e-041638445fc836444bc156c8248abee001b0ecbe43f980c9
ToppCelldroplet-Fat-Mat-18m-Myeloid-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1F OAS3 ATP1A3 MMP9

2.62e-04164844a27b9b3380f29bb17c9f787423f2591f2b9cf33e
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GIPR ABCC3 GSTO2 INO80D

2.62e-04164844d6f71d804bb65301c02ea4e6673e20688b5fcd5b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DPP4 ERN1 CD226 HYAL2

2.62e-041648448f3255d7f67890389a768453492243ea982eb38a
ToppCelldroplet-Lung-nan-18m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLOD3 MYO1F ATP1A3 GPR132

2.68e-04165844e32697321cef424c2ad4e11ee9da3e510d5ce505
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPP4 ROS1 MDGA1 GABRA5

2.68e-04165844fee7f2f8d0e25c0d067adc73f8913721bd709a3e
ToppCelldroplet-Lung-nan-18m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLOD3 MYO1F ATP1A3 GPR132

2.68e-041658440fbdd043e11aa8dbff4cd3a4da1b2feb49878a09
ToppCellfacs-MAT-Fat-18m-Myeloid|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1F PTAFR ATP1A3 MMP9

2.74e-041668449116be2805c34881debb999d8417e43832fcf2f2
DrugAGEPC

SELE MKLN1 GABRQ PTAFR MMP9 DYNC1H1 PEX26 GABRA3 GABRA5

7.31e-06356859CID000461545
DrugTrimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; PC3; HT_HG-U133A

DPP4 OASL TSSK2 ADGRL1 LRRC2 ATP1A3 DNAH7

8.81e-061968574100_DN
DrugCefotiam hydrochloride; Down 200; 7.2uM; MCF7; HT_HG-U133A

USP34 MYO1F OTUD4 ADGRL1 OAS3 TUBGCP2 MMP9

9.11e-061978573319_DN
DrugC5-substituted pyrrolidine 31

DPP4 DPP9

1.38e-052852CID010339570
Drugneostigmine

GABRQ ATP1A1 ATP1A3 GABRA3 GABRA5

1.87e-0587855CID000004456
Drugzileuton

SELE TJP1 PTAFR MMP9

2.85e-0547854ctd:C063449
Drugdihydroxyaflavinine

GABRQ GABRA3 GABRA5

3.29e-0517853CID000156857
DrugLosartan

NDST1 TJP1 ATP1A1 CUBN ATP1A3 MMP9

3.60e-05165856ctd:D019808
Drugcoproporphyrin I

DPP4 DPP9 F7

3.93e-0518853CID000068271
DrugSureCN3749646

DPP4 DPP9

4.12e-053852CID011530920
DrugSureCN3745540

DPP4 DPP9

4.12e-053852CID011974437
DrugSureCN3749947

DPP4 DPP9

4.12e-053852CID011974435
DrugABT-279

DPP4 DPP9

4.12e-053852CID016049769
DrugCyanopyrrolidine 39

DPP4 DPP9

4.12e-053852CID011117606
DrugCyanopyrrolidine 38

DPP4 DPP9

4.12e-053852CID010932707
DrugSureCN3748611

DPP4 DPP9

4.12e-053852CID011974325
DrugDiprolyl-alanine

DPP4 DPP9

4.12e-053852CID000193559
Drugsulfobromophthalein

ABCC3 DPP4 DPP9 GSTO2 F7

4.23e-05103855CID000005345
Drugtriazolam

GABRQ PTAFR GABRA3 GABRA5

4.96e-0554854CID000005556
Drugprostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A

OASL ADGRL1 CHD4 C5 EPAS1 PEX26

6.42e-051838566547_UP
DrugMonobenzone [103-16-2]; Down 200; 20uM; MCF7; HT_HG-U133A

STIM1 USP34 SLC44A1 OTUD4 TUBGCP2 PEX26

7.02e-051868563391_DN
Drugetizolam

GABRQ PTAFR GABRA5

7.35e-0522853CID000003307
Drugphenobarbital quinidine

ABCC3 GABRQ GABRA3

7.35e-0522853ctd:C033457
DrugAC1L19X5

ACAD10 ATP1A1 ATP1A3

7.35e-0522853CID000000741
Drugparthenolide

SELE ABCC3 C5 MMP9

7.52e-0560854ctd:C002669
Drug5 beta-pregnanediol

ABCC3 GABRQ GABRA3 GABRA5

7.52e-0560854CID000012547
Drugglycylproline 4-nitroanilide

DPP4 DPP9

8.22e-054852ctd:C042892
DrugFlumazenil

GABRA3 GABRA5

8.22e-054852DB01205
Drugetizolam

GABRA3 GABRA5

8.22e-054852ctd:C044610
DrugApApA(Sp)A

OASL OAS3

8.22e-054852CID000501019
DrugApA(Sp)A

OASL OAS3

8.22e-054852CID000501015
DrugApA(Sp)ApA

OASL OAS3

8.22e-054852CID000501017
DrugA(Sp)ApA

OASL OAS3

8.22e-054852CID000501013
Drugadenosine N'-oxide

OASL OAS3

8.22e-054852CID000459896
Drugpoly(I,8-azidoI).poly(C

OASL OAS3

8.22e-054852CID003081572
Drug15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A

DNAH3 OASL MKLN1 OTUD4 C5 EPAS1

8.37e-051928567526_UP
DrugBB-882

SELE PTAFR PRSS58

8.43e-0523853CID000060856
DrugSparteine (-) [90-39-1]; Down 200; 17uM; MCF7; HT_HG-U133A

OASL ADGRL1 OAS3 DIXDC1 INO80D PEX26

8.86e-051948564391_DN
DrugEthambutol dihydrochloride [1070-11-7]; Down 200; 14.4uM; PC3; HT_HG-U133A

DOCK1 ABCC3 TSSK2 ADGRL1 EPAS1 PEX26

8.86e-051948564001_DN
DrugRamipril [87333-19-5]; Up 200; 9.6uM; PC3; HT_HG-U133A

CDK9 OASL TSSK2 ACAD10 DNAH7 EPAS1

9.11e-051958567144_UP
DrugEtofenamate [30544-47-9]; Down 200; 10.8uM; HL60; HT_HG-U133A

DNAH3 ACAD10 TUBGCP2 PLOD2 EPAS1 PEX26

9.37e-051968562907_DN
DrugMidecamycin [35457-80-8]; Up 200; 5uM; MCF7; HT_HG-U133A

SLC44A1 ERN1 OASL ADGRL1 OAS3 INO80D

9.37e-051968565345_UP
DrugDelcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A

DOCK1 DNAH3 SLC44A1 OTUD4 DIXDC1 INO80D

9.37e-051968563613_DN
Drugmethohexital

GABRQ GABRA3 GABRA5

9.60e-0524853CID000009034
DrugMetformin hydrochloride [1115-70-4]; Down 200; 24.2uM; PC3; HT_HG-U133A

DOCK1 ABCC3 DPP4 MYO1B CHD4 ACAD10

9.91e-051988561816_DN
DrugFamotidine [76824-35-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A

DPP4 ERN1 MYO1F ATP1A3 INO80D GABRA5

9.91e-051988561529_UP
DrugHippeastrine hydrobromide [22352-41-6]; Up 200; 10uM; PC3; HT_HG-U133A

DPH1 DPP4 SLC44A1 OASL ADGRL1 EPAS1

9.91e-051988567381_UP
DrugBergenin monohydrate [477-90-7]; Down 200; 11.6uM; PC3; HT_HG-U133A

DPP4 DNAH3 MKLN1 OAS3 C5 TUBGCP2

1.02e-041998565870_DN
Drugprochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A

USP34 ABCC3 OASL ADGRL1 MYO1B PEX26

1.02e-041998565575_DN
DrugClebopride maleate [84370-95-6]; Down 200; 8.2uM; PC3; HT_HG-U133A

STIM1 DPH1 ABCC3 MYO1B ACAD10 C5

1.02e-041998566311_DN
DrugEszopiclone

GABRA3 GABRA5

1.37e-045852DB00402
Drugprodipine

DPP4 DPP9

1.37e-045852CID000065775
Drug22,23-dihydrobufalin

ATP1A1 ATP1A3

1.37e-045852CID000195392
DrugZopiclone

GABRA3 GABRA5

1.37e-045852DB01198
Drugthevetin A

ATP1A1 ATP1A3

1.37e-045852CID000441873
Drugarginyl(PMC)-pyrrolidine-2-nitrile

DPP4 DPP9

1.37e-045852CID000487437
Drugdehydro-histidinohydroxymerodesmosine

PLOD3 PLOD2

1.37e-045852CID003037599
Drug3-acetylstrophanthin

ATP1A1 ATP1A3

1.37e-045852CID003082282
Drugalanylproline-4-nitroanilide

DPP4 DPP9

1.37e-045852ctd:C083013
DrugBAPN

PLOD3 COL22A1 MMP9 PLOD2

1.45e-0471854CID000001647
DrugTexas Red

ABCC3 ADGRL1 CNP

1.54e-0428853CID000452705
Drugstilbene oxide

ABCC3 GSTO2 GPR132 DYNC1H1

1.71e-0474854CID000028649
DrugNSC9567

SELE TACR3 ATP1A1 ATP1A3 GSTO2

1.87e-04141855CID000003001
Drug3-isothujone

GABRQ GABRA3 GABRA5

1.90e-0430853CID000011027
Drugcathepsin C substrate

DPP4 DPP9

2.05e-046852CID003508173
DrugMeprobamate

GABRA3 GABRA5

2.05e-046852DB00371
DrugFlunitrazepam

GABRA3 GABRA5

2.05e-046852DB01544
Drugpyridinium formate

PLOD3 PLOD2

2.05e-046852CID013326228
DrugII 19

DPP4 DPP9

2.05e-046852CID000040321
DrugProtease Inhibitors

DPP9 MMP9

2.05e-046852ctd:D011480
DrugNVP-DPP728

DPP4 DPP9

2.05e-046852CID009796290
DrugMK-251

DPP4 DPP9

2.05e-046852CID000176160
DrugMX220

OASL OAS3

2.05e-046852CID000514000
DrugETH157

ATP1A1 ATP1A3

2.05e-046852CID000563154
DrugCGS 8216

GABRQ GABRA3 GABRA5

2.53e-0433853CID000104916
DrugAC1L2FYN

GABRQ GABRA3 GABRA5

2.53e-0433853CID000071333
Drugclonazepam

GABRQ ATP1A3 GABRA3 GABRA5

2.53e-0482854CID000002802
DrugQuazepam

GABRA3 GABRA5

2.86e-047852DB01589
DrugEpostatin

DPP4 DPP9

2.86e-047852CID006449105
Drugo-Py

DPP4 DPP9

2.86e-047852CID009942336
Drugdihydrodigitoxigenin

ATP1A1 ATP1A3

2.86e-047852CID000107549
Drugflurazepam

GABRQ GABRA3 GABRA5

3.01e-0435853CID000003393
Drugsodium; lithium

SELE ATP1A1 ATP1A3

3.28e-0436853CID012725854
DrugAC1LCF1F

ABCC3 DPP4 DPP9 ADGRL1 F7

3.45e-04161855CID000627275
Drugsecobarbital

GABRQ GABRA3 GABRA5

3.56e-0437853CID000005193
DrugAdinazolam

GABRA3 GABRA5

3.80e-048852DB00546
DrugCID6451162

DPP4 DPP9

3.80e-048852CID006451162
DrugHHMD

PLOD3 PLOD2

3.80e-048852CID000171068
DrugFludiazepam

GABRA3 GABRA5

3.80e-048852DB01567
DrugClotiazepam

GABRA3 GABRA5

3.80e-048852DB01559
DrugCinolazepam

GABRA3 GABRA5

3.80e-048852DB01594
DrugPrazepam

GABRA3 GABRA5

3.80e-048852DB01588
DrugEstazolam

GABRA3 GABRA5

3.80e-048852DB01215
DrugV-V2

OASL OAS3

3.80e-048852CID000198267
DrugHalazepam

GABRA3 GABRA5

3.80e-048852DB00801
Drugcoumalic acid

PLOD3 PLOD2

3.80e-048852CID000068141
Drughydroxyallysine

PLOD3 PLOD2

3.80e-048852CID000153008
DrugP32/98

DPP4 DPP9

3.80e-048852CID006918464
Drugimidazolelactate

DPP4 DPP9

3.80e-048852CID000000793
DrugDMCM

GABRQ GABRA3 GABRA5

3.85e-0438853CID000104999
Diseasenewborn respiratory distress syndrome (implicated_via_orthology)

NDST1 EPAS1

2.23e-053812DOID:12716 (implicated_via_orthology)
Diseasehyperglycemia (biomarker_via_orthology)

GIPR MMP9 EPAS1

2.56e-0521813DOID:4195 (biomarker_via_orthology)
DiseaseBipolar Disorder

DIXDC1 ATP1A1 ATP1A3 MMP9 MDGA1 GABRA3 GABRA5 NEDD4

5.04e-05477818C0005586
Diseasebipolar disorder (is_implicated_in)

ATP1A3 GABRA3 GABRA5

6.92e-0529813DOID:3312 (is_implicated_in)
Diseasefamilial hemiplegic migraine (implicated_via_orthology)

ATP1A1 ATP1A3

1.55e-047812DOID:0060178 (implicated_via_orthology)
Diseaseneutropenia (implicated_via_orthology)

C5 PTAFR

1.55e-047812DOID:1227 (implicated_via_orthology)
Diseasebilirubin metabolic disorder (biomarker_via_orthology)

ABCC3 F7

1.55e-047812DOID:2741 (biomarker_via_orthology)
Diseasecoronary artery disease (is_implicated_in)

SELE CUBN MMP9 F7

1.69e-04100814DOID:3393 (is_implicated_in)
DiseaseBone neoplasms

MMP9 PLOD2

2.06e-048812C0005967
DiseaseMalignant Bone Neoplasm

MMP9 PLOD2

2.06e-048812C0279530
Diseaseintracranial aneurysm (is_implicated_in)

COL22A1 MMP9

4.83e-0412812DOID:10941 (is_implicated_in)
Diseasedodecanedioate measurement

MDGA1 XPR1

4.83e-0412812EFO_0021054
Diseasenervous system disease (implicated_via_orthology)

ATP1A1 ATP1A3

4.83e-0412812DOID:863 (implicated_via_orthology)
DiseaseMalformations of Cortical Development

NDST1 DYNC1H1

6.63e-0414812C1955869
DiseaseCortical Dysplasia

NDST1 DYNC1H1

6.63e-0414812C0431380
DiseaseSclerocystic Ovaries

SPTBN4 LRATD1 PTAFR CEP55

6.76e-04144814C1136382
DiseasePolycystic Ovary Syndrome

SPTBN4 LRATD1 PTAFR CEP55

6.76e-04144814C0032460
DiseaseSchizophrenia

CLVS2 GABRQ DIXDC1 CHD4 TACR3 MMP9 MDGA1 CNP GABRA5

7.03e-04883819C0036341
Diseasebrain edema (biomarker_via_orthology)

C5 MMP9

7.64e-0415812DOID:4724 (biomarker_via_orthology)
DiseaseKeloid

HYAL2 NEDD4

9.85e-0417812EFO_0004212
Diseasemultiple sclerosis (is_implicated_in)

MMP9 CNP GABRA3

1.08e-0373813DOID:2377 (is_implicated_in)
DiseaseDiGeorge syndrome (implicated_via_orthology)

DOCK1 NDST1

1.23e-0319812DOID:11198 (implicated_via_orthology)
DiseaseCOVID-19, osteoarthritis

DPP9 LRRC2

1.37e-0320812MONDO_0005178, MONDO_0100096
Diseaseurticaria

STIM1 LRRC2

1.37e-0320812EFO_0005531
Diseasehypothyroidism (biomarker_via_orthology)

PLOD3 PLOD2 F7

1.41e-0380813DOID:1459 (biomarker_via_orthology)
Diseasepulmonary hypertension (biomarker_via_orthology)

MMP9 EPAS1 HYAL2

1.41e-0380813DOID:6432 (biomarker_via_orthology)
Diseasekidney disease (biomarker_via_orthology)

ABCC3 MMP9

1.51e-0321812DOID:557 (biomarker_via_orthology)
Diseasealcohol use disorder (implicated_via_orthology)

GIPR ATP1A1 ATP1A3 GSTO2

2.07e-03195814DOID:1574 (implicated_via_orthology)
DiseaseMyocardial Infarction

ATP1A1 MMP9 F7

2.30e-0395813C0027051
Diseaseadult respiratory distress syndrome (is_marker_for)

C5 MMP9

2.32e-0326812DOID:11394 (is_marker_for)
DiseaseKallmann Syndrome

ANOS1 TACR3

2.32e-0326812C0162809
Diseaseacute kidney failure (implicated_via_orthology)

PTAFR EPAS1

2.50e-0327812DOID:3021 (implicated_via_orthology)
DiseaseCerebral Hemorrhage

MMP9 F7

2.69e-0328812C2937358
Diseaseobesity (is_marker_for)

GIPR MMP9 F7

2.74e-03101813DOID:9970 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
YVWLETQGTVIYNPR

EPAS1

316

Q99814
RIENLELVPVEYQWY

AVIL

401

O75366
PRDNQLYVWNNYFVV

ADGRL1

376

O94910
IENPYWSVRALVQQY

DIXDC1

191

Q155Q3
QLLNNYPVYITSKQW

BEND4

386

Q6ZU67
LPWVRYITQNGDYQL

AP1M1

406

Q9BXS5
NQQWLVYDQQREVYV

CEP55

181

Q53EZ4
DYIPRQVRTWVKQYR

ACAD10

416

Q6JQN1
VIPWVIVRYLYENTQ

GIPR

271

P48546
ISEQPFLLVTYLWQY

DHRS7

286

Q9Y394
SNYNFEIPKTIWRIQ

DPH1

56

Q9BZG8
LNPAVYRNVEYEIWL

OTUD4

251

Q01804
LWVYVYVDPNNVLDA

ABCC3

551

O15438
KRVIATYQNIAVYEW

DUOX1

281

Q9NRD9
YSYVLQWTQREPDAV

MDGA1

656

Q8NFP4
KRVGVWNVPYISQAY

PLOD3

451

O60568
QVGYEDQWLQLLRTY

PLOD3

616

O60568
SIEPVIYVVQRRWNY

ANOS1

211

P23352
ITYWIQNYSEDLPRA

MMP9

121

P14780
YAQQVQAPVELYSDW

PADI6

461

Q6TGC4
LVPYVVNVSWATQYC

HYAL2

351

Q12891
QEWVQENYLEYRQAP

MAGEA8

251

P43361
QNWVQEKYLVYRQVP

MAGEA11

361

P43364
YIYLVIQWRFVNRIQ

NEDD4

1151

P46934
PQYSWKRYNILNQEQ

GPA33

171

Q99795
ETRQENYWLIQYQRL

LRSAM1

541

Q6UWE0
VQREVNSYLVQVYWP

GABRQ

261

Q9UN88
NSYLVQVYWPTVLTT

GABRQ

266

Q9UN88
EILLSFPQNYYIQWL

LMBR1

86

Q8WVP7
SYGQQWTYEQRKIVE

ATP1A1

901

P05023
EVLSWVLQYYQVPEK

PEX26

101

Q7Z412
VVNINLRNKPEWYYT

GSTO2

51

Q9H4Y5
VYPVHVQLYEAWKQV

NDST1

436

P52848
WYISNTLIQIIPTYI

LRRC2

126

Q9BYS8
SPSYYWIGIRKVNNV

SELE

66

P16581
WYRYRPLVAELVVQN

LRATD1

181

Q96KN4
YVWNNDIYVKIEPNL

DPP4

166

P27487
NLVYWATYVNRESAI

GABRA3

471

P34903
NLVYWATYLNREPVI

GABRA5

441

P31644
KYWDQRYTIVQQQIP

TUBGCP2

426

Q9BSJ2
GYAPYVNRIVQQWNL

PLOD2

171

O00469
WYQQYVKARSPRANL

OASL

216

Q15646
NNYPNNWECIYRITV

CUBN

1066

O60494
ENKTQPQVAYQYWPL

ERVK-10

201

P87889
IPPLNNLQWYIYEKQ

GKN2

91

Q86XP6
VIYYQVKQPRWFETV

DOCK1

481

Q14185
LRYYWVAKDVQVQII

DNAH3

1371

Q8TD57
VLWIQNYASPVVAFY

ERN1

216

O75460
NYASPVVAFYVWQRE

ERN1

221

O75460
YWKSPRVPSEVQQRY

DCDC2C

216

A8MYV0
NVQPYVVYEEVTNVW

DPP9

406

Q86TI2
YVNPVIKWLSEEQRY

C5

1266

P01031
RSWLINYIQEILRNY

DNAH7

2226

Q8WXX0
VKQYAVQSQLPVYEW

MTFMT

96

Q96DP5
YQYQVVLVEPKTAWR

CNP

141

P09543
SNVSYFVEWIKRQIY

CORIN

1021

Q9Y5Q5
YIWQVIDQYSIPQVS

COL22A1

311

Q8NFW1
SYGQQWTYEQRKVVE

ATP1A3

891

P13637
PYQVAWSIRETLRYQ

INO80D

341

Q53TQ3
NTYITWIDKYQAQLV

DYNC1H1

1736

Q14204
YQQDYTVWVLPLIIV

SLC44A1

561

Q8WWI5
YTYPQGTWQKVIQVV

CD226

111

Q15762
QPNRYTNRVVTLWYR

CDK9

181

P50750
YARWQDIQNDPRYAI

CHD4

1746

Q14839
LESRIQEWYEFQIPY

KRT36

121

O76013
LVTQYRQLCIYWTIN

OAS3

1001

Q9Y6K5
YTGTLPLWVIYIRNQ

GPR132

91

Q9UNW8
QDTLYWNNYKTPVQI

UTP15

21

Q8TED0
KIFYYIPWIENVIQN

PRSS58

226

Q8IYP2
WNLYIVNTISPVQLY

HPS3

486

Q969F9
YISQQEYKPRWSQII

MKLN1

241

Q9UL63
FLITLPLWIVYYQNQ

PTAFR

66

P25105
VYTRVSQYIEWLQKL

F7

436

P08709
ITVQYYLWPQGLVRE

SLC38A8

191

A6NNN8
LTAIYQQLNRWKYIQ

TACR3

321

P29371
EVVQWLITYVELPQY

STIM1

136

Q13586
VNQPWYIHALYTVIR

CLVS2

201

Q5SYC1
ITPEWRKQYIQYEAF

XPR1

11

Q9UBH6
TYYLWPRDQNAEQIR

SEC63

31

Q9UGP8
CYNYIRVLVPWDSQT

SEMA6C

121

Q9H3T2
VALEQQYWLYQLSRQ

SPTBN4

1721

Q9H254
QYWLYQLSRQVSELE

SPTBN4

1726

Q9H254
YWAGKTYVIQRQSVL

ROS1

761

P08922
NAVDRLNYAQWYPIV

TJP1

711

Q07157
YILQRIWEVIEYNPS

USP34

2626

Q70CQ2
VLQSIPYQPKVYDIW

TSSK2

186

Q96PF2
YNTVTRQWLYLKENT

KLHL42

421

Q9P2K6
QIVIAAWYRRYAQQK

MYO1B

731

O43795
YVQEGIRWTPIQYFN

MYO1F

426

O00160